Welcome to FlyGATE
FlyGATE is a knowledge database dedicated to the transposable element (TEs) sequences of the Drosophila melanogaster genome.
TEs are moderately DNA repeated sequences that have the intrinsic ability to move along chromosomes. TEs constitute a large fraction of most genomes and are known to have played a major role in evolutionary processes, as they constitute a source of genetic innovation. Knowledge of the distribution of TE insertions along the chromosomes and of the characteristics of their sequences is a prerequisite to understand their origin, dynamics, and phylogeny, their precise influence on genomes, the way they are regulated, and the forces that are acting to control them within genomes, populations, and species.
FlyGATE centralizes the information concerning TEs and their interactions with genes within the Drosophila melanogaster genome to make the analysis of TE sequences easier. FlyGATE relies on GATE (Genome Analysis for Transposable Elements) an object-oriented data model that represents the structural, dynamic, and evolutionary aspects of TEs in relation to host genes in eukaryotes. This ontology describes major concepts such as TE classification, genomic elements (genes and other DNA sequences) and their features, maps (physical and cytogenetical), and localization of the genomic elements on the maps.