Toggle navigation
TopoIBase
Data
Taxonomy and VLD families
Downloads
My selection
Upload to selection
Selection 1
Selection 2
Selection 3
Tools
Blast
MUSCLE
VLD
About
How to use
Acknowledgements and references
Contact
Tests
Search more
Download
fasta
tsv
Download
Blast
Muscle
VLD
Add to selection
Selection 1
Selection 2
Selection 3
All selections
Family 2
Informations
Name
2
# topoisomerases
68
Sub-families
No subfamilies.
Topoisomerases
Select all
Name
Family
Sequence
(12) DNA topoisomerase 3 [Bacillus anthracis str. CDC 684]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(22) DNA topoisomerase 3 [Clostridium ljungdahlii DSM 13528]
2
MGKILVLAEKPSVGREIARVLKCRKKGNGWLEGEKYIVTWALGHLVTLADPEAYDDKYKTWKLEDLPMLPKYLKLVVIKQTGKQFNAVKEQLNRKDVTEIVIATDAGREGELVARWIIEKARVNKPIKRLWISSQTDKAINEGFRNLKPSSQYDNLYRAAQCRAEADWIVGLNVTRALTCKHNAQLSAGRVQTPTLAMIVHREEEIKNFKPKDYYSIIGNANGYTLQWQNGNGHFNTFDENFANKVVSKVNGQNGKILDVIKSDKKKYAPALYDLTELQRDANRLFGYSAKQTLSIMQRLYENYKFLTYPRTDSRYISADIVPTLPERLKAISVGNYSKFAMEIMRGKIRAHKGFVDDSKVSDHHAIIPTEEKVILSKLSNEERKVYDLVVKRFLSVMLPPFEYVQTTVKAEINGENFAASGKVIKSKGWKAVYDKNEDFDDNDGLHENQLKEQVLPNLNRGDSIKLTAVKMHKGQTKPPARFNEGTLLSAMENPQKYINMNKEYAKTLGETGGLGTVATRADIIEKLFNTFYIEKKGKEIIPTSKGKQVVELVPEDLKSPLLTAKWETDLNLISKGKLNDKSFIGNMRNYSVKLVEDVKGSHDKFRHDNLSGAKCPECGKYMLEVNGKHGRMLVCQDRACGHRENLAKLTNARCPECHKKLELRGHGDGQVYVCINNNCNFREKASSFNKRFDNKQGKNSKRDVANYMKKMKKESEVPMNSALADALAKLKLK
(62) DNA topoisomerase 3 [Bacillus licheniformis DSM 13 = ATCC 14580]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFQAVKSQLIRKDVKDIVIATDAGREGELVARWIIEKAKVTKPLKRLWISSVTDKAIKDGFKNLKNGKDFENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREEDIKNFKPVPYFGLRAAVDGMTLTWQDKKTSQTRTFNASVTSQLAGALQGKPAVIVDLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSNDIVPTLKDRLEGMQVKPYAQHVARILKRGVKANKSFVNDAKVSDHHAIIPTEEPLALGALSEKERKLYDLIAKRFLAVLMPPFEYEETKVFAEIGGETFTAKGKTVQSQGWKAVYDFADEDDDEEEKDQTLPKLAKGDTLSVRSLTETKGETKPPARFNEGTLLSAMENPAAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNTFLIEKKGKDIYITSKGKQLLELVPSDLKSPALTAEWEQKLSGIAKGKLKSSAFIKEMKEYAKQTIREIKSSNQKFKHDNITGTHCPDCGKLMLKVNGKRGTMLVCQDRECGHRKTVAKQTNARCPVCHKRMELRGHGEGQTFACVCGHREKLSVFEKRRAKDKNSKASKRDVHSYMKKQNKDEPINNALAEQLKKLKLDQ
(63) DNA topoisomerase 3 [Bacillus licheniformis DSM 13 = ATCC 14580]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFQAVKSQLIRKDVKDIVIATDAGREGELVARWIIEKAKVTKPLKRLWISSVTDKAIKDGFKNLKNGKDFENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREEDIKNFKPVPYFGLRAAVDGMTLTWQDKKTSQTRTFNASVTSQLAGALQGKPAVIVDLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSNDIVPTLKDRLEGMQVKPYAQHVARILKRGVKANKSFVNDAKVSDHHAIIPTEEPLALGALSEKERKLYDLIAKRFLAVLMPPFEYEETKVFAEIGGETFTAKGKTVQSQGWKAVYDFADEDDDEEEKDQTLPKLAKGDTLSVRSLTETKGETKPPARFNEGTLLSAMENPAAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNTFLIEKKGKDIYITSKGKQLLELVPSDLKSPALTAEWEQKLSGIAKGKLKSSAFIKEMKEYAKQTIREIKSSNQKFKHDNITGTHCPDCGKLMLKVNGKRGTMLVCQDRECGHRKTVAKQTNARCPVCHKRMELRGHGEGQTFACVCGHREKLSVFEKRRAKDKNSKASKRDVHSYMKKQNKDEPINNALAEQLKKLKLDQ
(116) DNA topoisomerase 3 [butyrate-producing bacterium SM4/1]
2
MKSLVIAEKPSVGKDIARVLGCRKSADGCLEGDKYIVTWAFGHLVELAAPEEYDKKYKDWNMADLPMMPEPFKLEVIGKTAKQFGVVKRQLFRNDVKDIVIATDAGREGELVARFILMKAGCRKPLKRLWISSVTDRAIKEGFSRLRDGREYNHLRDAAMCRAEADWLVGLNATRALTCKYNAQLSCGRVQTPTLAIIAKREEEIRNFRPKAYWGLTARTSKPALTLTWQDKKSGGMRSFDRDRMEGLQKSLRDQQVWITKVKKTPKKTMAPLLYDLTELQRDANKRFGYSAKETLNIMQRLYENHKVLTYPRTDSRYLSSDVADTIHDRLAACGTGPYRKLAGKLSKNVWTKKASFINDGKVTDHHAIIPTEQFVQLQNMTSEERKIYDLVVRRFLAVLYPAAEYDETVITAEIGGEIFTARGKVMRTPGWREVYESADESGLSGTGGYLDEEDGDEDGEGPQNERVKAQTLPDLREGDVIGPAGISLTEGKTKPPAPFNEATLLSAMENPVRYMESGDRAMAKTLGETGGLGTVATRADIIEKLFSGFMLEKKGKDICLTSKAKQLLRLVPEDLRKPELTAQWEMRLSKIAKGEMKRDAFMEDIRTYTKDIVEEIKGGEGTFRHDNLTNTKCPRCGKRMLSVKGKNSQMLVCQDRECGYRETISRTSNARCPKCHKKMELRGKGENQMFSCVCGYKEKLSNFKERRQREGAGVTKRDVARYLNQQKKEEKMVNNPFADALKKMQEQDV
(190) DNA topoisomerase 3 [Desulfotomaculum ruminis DSM 2154]
2
MNKTLVLAEKPSVARDLARVLNCGKKGNGYFEGDQYIVTWALGHLVTLADPEAYDQKYHSWRLEDLPILPSYLKLVVIKQSSRQFYTVTAQMNRKDVAEIVIATDAGREGELVARWIIEKAQVKKAIKRLWISSVTDKAIRDGFRSLKKGQAYEHLYASAVARAEADWLVGINATRALTCKHNAQLSCGRVQTPTLAIIAKREEEIKNFKPKNFYGITAVSNGLKLTWQDSRSKDTKTFDADYCDKILLAIKNKPAEIIEVEKAHKKSFPPQLYDLTELQRDANRLFGYSAKETLSHMQRLYEHHKVLTYPRTDSRYLSTDMVETLKDRVEACRDNPYTKMAFKILKNPIQISKSFVDNSKVSDHHAIIPTEQPLCLSALNDKERKIYDLVVRRFLAVLYPPFEYEQTTLKAKIGQELFIAKGKRVLAQGWKEVYDNQFEDEDQPEGLAEQRLPGINKGDRLKISSISQTKGETKPPEPFNEGSLLSAMENPTKYMANQDKELIKTIGKTGGLGTVATRADIIEKLFNSFLIEKKGKHIFITSKGRQLLELVPGDLKAPDLTAEWEQKLEAIAKGVLNKNHFIDEMKQYAKLLVHEVKNSENKFRHDNLTGNKCPQCGKRMLEVNGKKGKMLVCQDRECGYRKGLSKITNARCPNCHKRMELHGEGEGQIFVCPCGYREKLTAFNERRGKEKTGSLSKKELSQYLQNQKKDEKDGLMNTALADALAKLKQP
(195) DNA topoisomerase 3 [Clostridium botulinum A str. ATCC 19397]
2
MGKVLVLAEKPSVGRDLAKVLKCNKKGNGYLEGNKYIVTWALGHLITLSDPESYDEKYKKWSMDTLPMLPKRMKTTVIKKTSKHFSEVRKVMIRKDVEELVIATDAGREGELVARWIIDKVGFKKPIKRLWISSQTDKAILDGFRNLKPGKNYENLYHSAVCRSEADWIVGLNVTRALTCRYNAQLSAGRVQTPTLAMIVQREEEIKNFKPRDYYSIEGKTKGFTMHWESAKGRFNTFDEDLAKKVVSKVTGKEGKIIEVTESDKKKYAPALYDLTELQRDANRIFGYSAKQTLSIMQRLYENHKILTYPRTDSRYISKDVVGTLKDRLKAISISNYSKFTNEILKGNIKAHKGFVDDSKVSDHHAIIPTEEKPKLGNLSGEERNIYDLVIKRFLSVMLPPFEYIQTTIKSEVIGEKFVARGKVIKSKGWKAVYDREEFDDKNNNSDSDDIKDQTLPKVNKGDGIKFSNFKINKGQTKPPARFNEGTLLSAMENPQRYINLDKESSKTLGETGGLGTVATRADIIEKLYNTFYIEKRGKEIVPTSKGKQVIDLVPKDLKSPLLTAKWERELDSISKGNLRGQIFINKMRDYSTKLVEDVKNSKDKYVHDNLTGKKCPQCGKYMLEVKGKNGVINVCQDRECGYRENVSRFTNVRCPECHVKLELRGEGQGQIYVCTRCSFREKLSSFNKKYRNNQEKLNKRDVTKYMKKMQKENDEPINSALAEALSKLKL
(216) DNA topoisomerase [Bacillus megaterium WSH-002]
2
MKSLVLAEKPSVARDLARVLGSTQTKKGYIEGPKYVVTWALGHLVELQTPEDYDNQYKTWRLEDLPIMPEKMKLKVIRKVSSQFRTVSDLAKRKDIGELIIATDAGREGELVARWIMEKVRWNKPFKRLWISSQTDKAIRDGFKQLKPGKEFNRLYDSAVCRSEADWLIGLNVTRALTTKYEEPLSAGRVQTPTLAMIIEREQVINTFKPSEYWTLTAQFSSFEAAWQKGNEKRIFDEKRAKELHSKLSGEAVVNTIKRKMHKEAQPLPYDLNELQRDANKRFNFSAKKTLNVLQKLYEQHKLVTYPRTDSRYLTTDMVSTMKERLESISAVYKEEVRPILRNAQLPKRVVNNEKVSDHHAIIVTDQPVFLQDLSADERKLYDLIAKRFISLFYPAYEYEVVKAELEVNGEQLVASGKQVVNAGFKKVSGGESEATVKLPDMKEGSKLSIQDVTMKSAFTEPPQRYTEADLLGQMEKHNLGTPATRADIIEKLLQNESIDRQNNRLHATKKGKQLIDLVADELKSPELTAKWERELEAIAKGKGNAKEFLTNIREQTEKLVKQVKTSNQTYKPHNLTGSKCPECGTFLKEKKTKQGRVLVCSSLECSYRRAKDPKLSNRRCPQCHKRMEIHSGKAGTYFQCRSCQVVEKAEDKKKKISKREERKLLNKYNDDGAFGSSLGDALKQALQDKKD
(250) DNA topoisomerase 3 [Clostridium sp. BNL1100]
2
MGFTLVIAEKPSVARDLAKVLNCGQNANGYIMGKKYIVTWALGHLVTLADPEAYGNKYKTWNLEDLPMLPNKMELVVIKQTAKQYGVVRGLLNRADVDELVIATDSGREGELVARWIIMKAGFKKPIKRLWISSQTDKAIKEGFAKLRPSKEYDNLYYSAQSRAEADWLVGLNVTRALTCKYNAQLSAGRVQTPTLAMIVEREEEIRKFRPKDYWTISAQFNGFSVQWQDGRTNQTRTFNKEEADGIVAKITGQIGEVVEVKKETKKELPPLAYDLTELQRDANKKFSYSAKQTLNIMQRLYESHKLVTYPRTDSRYITDDIVPTLNERLKSIAVGPYAKLVQGVMRNKISVTKRFVDNSKVTDHHAIIPTEQFVDLSSLNSEERNIYDLIVKRFIAVLSQPFEYEQTTVKLNVAGESFYAKGKIVRSSGWKTVYDGFGKLDEDSDEDDNDQSLPDIQKGHKAKVVAPKAINGKTKPPARYTEATLLSAMEHPGKFVDNKALKEALESTSGLGTPATRADIIEKLFNTFYIERRGKEIYPTSKGTQLISLVPADLKSPELTAKWEQQLSLISKGKANSNAFVGEMKNYAKKLVGAVIASSEQFKHDNVTREKCPECGKYLLEVNGKKGKMHVCPDRECGYRKSVTVISNARCPECHKKMEIRGEGENKSFYCSCGYREKLDAFKKRKGEQVDKKDVARFMRQQDKDESINSALADALAKWKK
(268) DNA topoisomerase 3 [Clostridium cf. saccharolyticum K10]
2
MKSLVIAEKPSVGKDIARVLGCRKSADGCLEGDKYIVTWAFGHLVELAAPEEYDKKYKDWNMADLPMMPEPFKLEVIGKTAKQFGVVKRQLFRNDVKDIVIATDAGREGELVARFILMKAGCRKPLKRLWISSVTDRAIKEGFSRLRDGREYNHLRDAAMCRAEADWLVGLNATRALTCKYNAQLSCGRVQTPTLAIIAKREEEIRNFRPKAYWGLTARTSKPALTLTWQDKKSGGMRSFDRDRMEGLQKSLRDQQVRITKVKKTPKKTMAPLLYDLTELQRDANKRFGYSAKETLNIMQRLYENHKVLTYPRTDSRYLSSDVADTIHDRLAACGTGPYRKLAGKLSKNVWTKKASFINDGKVTDHHAIIPTEQFVQLQNMTSEERKIYDLVVRRFLAVLYPAAEYDETVITAEIGGEIFTARGKVMRTPGWREVYESADESGLSGTGGYLDEEDGDEDGEGPQNEERVKAQTLPDLREGDVTGPAGISLTEGKTKPPAPFNEAALLSAMENPVRYMESGDRAMAKTLGETGGLGTVATRADIIEKLFSGFMLEKKGKDICLTSKAKQLLRLVPEDLRKPELTAQWEMRLSKIAEGEMKRDAFMEDIRTYTKDIVEEIKGGEGTFRHDNLTNTKCPRCGKRMLSVKGKNSQMLVCQDRECGYRETISRTSNARCPKCHKKMELRGKGENQMFSCVCGYKEKLSNFKERRQREGAGVTKRDVARYLNQQKKEEKMVNNPFADALKKMQEQDV
(277) DNA topoisomerase 3 [Listeria welshimeri serovar 6b str. SLCC5334]
2
MTKTLVLAEKPSVGKDIGRVLGAKQGKNGYLEGGKYVVTWALGHLVTLADPERYDSKYKNWNMEDLPMLPEKMKLEPIKQTRKQYETVKKLMNRTDITTIVIATDAGREGELVARWIIDYAKIKKPLKRLWISSVTDKAIREGFEHLKPGKAYENLYHSAVARSEADWVVGINATRALTTKYNAQLSCGRVQTPTLAMIQHREEEIRNFQPREYYRITAQTEQECFTWNIGQTFDKALAEKLVKSLQGENAVITDVSMKEKKTFSPGLYDLTELQRDANNRYDFSAKETLNIMQTLYERHKVLTYPRTDSRFISTDIVPTLKERLTACGVGENAKAARQISGKPIKANKSFVDNSKVSDHHAIIPTEQPVSLGDLSDKERKIYDLVVKRFLAVLSDPYIYEETSVKAKIGQEDFTLKGKVIKSLGWKSIYGEAREPDQLTKMKKGDTIPVKRVNLETGKTKPPARFNEATLLSAMENPSKYMETTNKALAKTLGETGGLGTVATRADIIEKLFNSFSLEKQGKDIQITSKGRQLLELVPEDLKSPELTARWEQKLSKIAKGELDYRKFTAEMRDYAKKAVTEIKQNDKKFRHDNITSQKCPDCGKPMLKVKGKRGTMLVCQDRECGHRESVSRTTNARCPNCHKRMEMRGEGDKQIFVCVCGHREKLTAFQQRRDKEKNKNVSKTDVAKFMKKQNKQDEEPFNNPMAEALAKLKLDK
(285) DNA topoisomerase 3 [Ruminococcus sp. SR1/5]
2
MKSLVIAEKPSVARDIARVLHCSQKGNGTLEGKAYVVTWALGHLVTLADPEEYDKKYTKWELSTLPMMPEKMKLVVIRQTSKQYNAVKTQLYRKDIGEIIIATDAGREGELVARWILAKADCHKPIKRLWISSVTDKAIRDGFAHLKNGHDYDDLYRAAQARAEADWLVGMNGTRALTCKYNAQLSCGRVQTPTLAMIARREQEIREFKPEDYYGIILQAGNVRWTWRDGKSGSLRTFKKERAQEIQTKAGKSSLTITKVSRKPKKTYAPGLYDLTTLQREANQKYGFSAKETLNIMQRLYENHKVLTYPRTDSRYIGKDVVPTIKERLQACGTGPYRKLAGALVNKPIQTSAGFVDDKKVSDHHAIIPTEQFVQLDHMTNEERKIYDMVVRRFLSVLYPPAVYELVSMEGTAAGETFAASGRIVKSAGWREVYEGGWQDEDEEESGDKLKDQKLPELTEGQILTVEGAALTAGKTKPPARFTEATLLGAMENPVHFMESHDKKAAKTLGETGGLGTVATRADIIEKLFNSFMMEKRGNEIYITSKAKQLLELVPEELKKPELTADWEMKLSDIANGKLRQDKFLTGIRKYACEIVDEIKGGQGTFRHDNMTNKKCPNCGKHLLAVNGKNAKMLVCEDRECGYRETVSRTTNARCPKCHKRMEMLLKGKEETFVCQCGYKEKLSSFQARRAKEGAGVNKRDVQRYLKKQQKEANEPVNNAFAQALSGIKLD
(292) DNA topoisomerase 3 [Coprococcus catus GD/7]
2
MKTLVIAEKPSVGRDIARVLQCTRNSQGALEGEKYIVTWALGHLVTLADPEGYDAKYKSWRGEDLPMMPQHFKLVVIKQTHRQFQIVKNQLLRKDVGTIVIATDAGREGELVARWILKIAGNKKPVKRLWISSVTDKAIREGFKNLKDGRAYLNLYAAAEARAEADWLVGMNGTRALTCRYNAQLSCGRVQTPTLALIASREQEIKSFVPKKYYTLTTVSHGMTWNWQDGKSGSNRSFDRGRIQSIAEKAEKDEMVITDVQRTVKKSYSPGLYDLTELQRDANKRFGYSAKETLNIMQRLYENHKVLTYPRTDSRYIGKDVAETLKERLQACAVGPYRKVAGKLLLQPIRMDKRFVDDSKVSDHHAIIPTEQFVQLDHMSSEERKIYDLVVRRFLAVLYPPCEYEQIKLTGSCAGEKWTAGSRMMKEAGWQQAYESEWEEEDDDSLMTVTSMPKLEKGRKDTVMRPKVSEGQTKPPAYYNEGTLLTAMEKGNLGTVATRADIIDKLFNSFLMEKKDKDIRVTSKGRQLLGLVPEDLKKPELTADWEKKLLAISEGRLKKDVFISEIRGYTEEIVKEIAGGEGQFRHENLTNHLCPNCGKRMLSVQGKNSKMLVCQDRSCGYRESIARKTNARCPKCHKKMEMYGKGDAQTFVCTCGYKEKLSAFQNRRKKEGAGVSKRDVQQYMKRQQKEANEPINNAFAAAFAKLNLETKEGE
(297) DNA topoisomerase 3 [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305]
2
MKSLIIAEKPSVGRDIANTLNINEKRNGYFENNKYIVTWALGHLVTNATPEQYDASYKEWKLNDLPIIPNKMKTIVISKTRKQFSTVQSLINNNKVKDIIIATDAGREGELVARLILDKAHNKKPTKRLWISSVTNKAIKEGFNKLQDGRKFNNLYHAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVQMRQNEINHFKPQTYYTMKLNAAGLTFHCTKPQSHPDKTVLESIKKAIDGQSGHIASISKTHKKAYPQQLYNLTDLQQDAYKRFHLGPKETLNTLQTLYERHKLVTYPRTDSNYLTDDMVDTLKDRLKAIMATSLKDMAKAQMSQTFSSKQRFVNNNKVSDHHAIIPTEVRPDINQLSQRESKIYMMIAQRYLENLMPPHEYEAIAIELKVGQHTFTFKDKVTTKLGFKAIYENKESINTQIDQLQKGTKLNVTKILIEEHETTAPPYFNEGSLLKAMESPQKFFDLSDKKHDKTLKDTGGIGTVATRADIIEKLFNMNAIEARDGKIKVTSKGKQILELAPQKLTSPLLTAEWEEKLLLIEQGKYNASQFISEMKAFTNQVVNEIKESEQNYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPQCKTKKNVQRKTNARCPNCHKKMTLFGRGKDAVYRCVCGHTETQAQMDKRHKNKKSDKVNKKDLKKYMNNDEGIENNPFQDALKGLKF
(311) DNA topoisomerase 3 [Bacillus clausii KSM-K16]
2
MKKKAVLAEKPSVARDIARVLGCNQKGNGYLEGNGYIITWALGHLVTHADPEHYGKQYKTWKLEELPMLPKRLELVVIKQTAKQFHAVKHVLNRQDVGEVVIATDAGREGELVARWILEKAHVKKPVKRLWISSVTDKAIKDGFKQLKDGKRYETLYAAAAARAEADWYVGINGTRALTTKHNAQLSCGRVQTPTLAILADREEAIRKFVPKPYHTISVETKDGVTFRWADRRSKEERIFDDKRAKTLQEKLQQSAIVIDSVNAKTKRTPPPPLYDLTELQREANKRFGYSAKETLAALQRLYEQHKAVTYPRTDSRYLSSDLVETLKERLHAVDVQPFRKMVANAKKQGLANAKRQMVNDAKVSDHHALIPTEQPQSASAMSDKEAKLYHLIVRRFLANFFPPSESELTSVEATANGELLRAKGERLVSAGWRGQETGEEDEALARLLPAMSKGDKKAVKWVGMTQGKTSPPPRFNEGTLLAAMEKPAQHMEAKDETIKKTLAQAGGIGTVATRADIIEKLFSSFYIEKKGKDLYITSKGKQLLELVPAELKSPALTAEWEQRLEKIVQGKEQKQMFIAEMKEYAKAVVAQVKADTATFRHDNKTGEKCPECGKFLLEVNGKKGKMRVCQDRECGYRKNIAMTTNARCPKCKKKLELRGEGEGQVFACVCGHREKKAQFEQRRKQNKHKNVSKREVQSYMKKQNKQDQFANSALADQLAKLGLKGDDS
(329) Topoisomerase IA [Ruminococcus bromii L2-63]
2
MAFRLVIAEKPSVAQTIAAALGIKGKQDGYIEGGGYLISWCVGHLVQLAEAAAYGEQYKKMEF
(350) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(351) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(352) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(354) DNA topoisomerase 3 [Alkaliphilus metalliredigens QYMF]
2
MKKKLVLAEKPSVGRDLARVLNCNQKGNGYLEGKEYIVTWALGHLVTLADPETYSQKYKSWKLEDLPMLPDEMKLVVIQKTGKQFNAVKSQMVRKDVGEIIIATDAGREGELVARWIIEKVGVKKTIKRLWISSVTDKAIKDGFNKLKNGREYDNLYASAVARSEADWIVGLNATRALTTKYNSQLSCGRVQTPTLTIIAKREEEIQRFQPKTFYGAQVVAGDLKLTWQDQQTNSMRVFDETKIDQVIQSIQNQEVKVVDISKRHKKSYAPRLYDLTELQRDANKIFGYSAKETLSIMQKLYETHKALTYPRTDSRYITADIVGTLKDRLQACGVGPYKAFAAKVMQSSIKANKSFVDDAQVSDHHAIIPTEQSIYLGALSDQERKIYDLVVKRFLAVLYPPFEYEERTINAKLGKEHFIAKGKMVIHQGWKAIYGHQTEVSEDEDIADQILPNLNRGDTLKVNAISKTTGKTKPPALFTEGTLLTAMENPSKFMSNEDKTLIKTIGETGGLGTVATRADIIEKLFSSFSIEKRGKDIHITSKGKQLLQLVPEDLKSPGLTAEWEQNLSAIAKGKLNKNTFVNRMKEYTKTIVKEIKNSEAAFRHDNLTANKCPDCGKYMLEVNGKKGKMLVCQDRECGHRKIVAQKSNARCPDCKKKLELRGEGEAQIFVCSCGHREKLSTFKERRKKDQDKASKGEVNQYLKQQKKEEPINTALADALAKLKLD
(400) DNA topoisomerase 3 [Oceanobacillus iheyensis HTE831]
2
MSKTVVLAEKPSVGRDIAKVLGCHKKGNGFLEGSKYIVTWALGHLVTLADPDMYDSKYKTWRMEDLPMLPDHLKLVVMKKTGKQFQSVKTQLNRQDVVEIVIATDAGREGELVARWIIEKARVKKPIKRLWISSVTEKAIKDGFKQLKPGKNYWNLYQSAVARSEADWYVGLNATRALTTKHNAQLSSGRVQTPTLEMVSLREQEIKNFQPKKFYQLEAKTTKGHRFLWKNDENQNRIFSKNEAIKLEEKLSNKQATVVHVDKKLKKKHAQGLYDLTDLQRDANRIFQFSGKQTLSVMQKLYEQHKLVTYPRTDSRHLSTDIVSTLKDRVKACGVDEYAKIANTILNKELRLNKSVVDNAKVTDHHAIIPTEVPVVWTALDDKEKKIYHLIVQRFLAALSDPMEYEQTTITIDIAGEQFIANGKVTKRLGWKEIYKHNDEEDEIQPLNVTKGSKLTLKVELKEGETKPPERFTEGTILQAMENPTRYMGTNKKELVDTIKETGGIGTVATRADIIEKLFMNSYIELKGRNIYLTQTGRQLLDLAPEELRSPLLTAEWEQKLSLIAEGKLKKDQFIKEIKSYTKEAVTEIKQSSETFKHDNMTGTKCPKCGKLMLEIKNKHGKKLVCQDRSCGGKKNIAKFTNARCPNCHKRLELRGEGEGQIFTCKCGHREKLSTFQARKEKEKKQRVSKKDVKKYLNKQDEGFKNNALADALAKLKNDE
(405) DNA topoisomerase 3 [Clostridium tetani E88]
2
MGKTLVLAEKPSVGREIARVLKCNKNSRSYIESNKYVVTWALGHLVTLADPEVYDNKYKKWEMETLPMLPKYMKLCVIGKTSKQFNEVKKLMNRNDIDEIVIATDAGREGELVARWIIEKARVNKPIKRLWISSQTDKAIIDGFNNLKPGKDYENLYKSAVCRSEADWLVGLNVTRALTCKYNAQLSAGRVQTPTLALIVEREEEIKNFKPRDYYNIVAKTKGIQFNWQDKKGQMATFNEDFANNILAKVSGEIGNVTEVIEKDKKQYAPALYDLTELQRDANRIFGYSAKETLSIMQRLYENHKVLTYPRTDSRYISKDIVATIPQRLKSISIGIYSKFAEEILRGKIVAHKGFVDDSKVSDHHAIIPTEERVKLSNLSGDERKIYDLVIKRFLSVMLPPFEYIQTTIKVEVNGEVFIAKGKNIKHNGWKAVYNKEDLNEDNNDGDGLKEQVLPQIIKGDAIKFNLVNINKGQTKPPARFNEGTLLSAMENPQKYIKLNKEYAKTLGETGGLGTVATRADIIEKLYNSFYIEKKGKEIIPTSKGKQIIDLVPQDLKSPILTAEWEKKLELISKGKISGKEFINNMRNYSTKLVQDVKNSNEKYIHNNLTGTKCPNCEKYMLEVNGKRGKILVCQDRECGYRENISRFTNVRCPECHKKLELRGEGEGQIYVCSKCTFREKLSSFNKRFKEKGNNADKREVSRYMKKMKEQDKEPMNSALADALAKLNLK
(410) DNA topoisomerase 3 [Clostridium saccharolyticum WM1]
2
MKSLIIAEKPSVARDIARVLHCTKNHDGVIEGEAYVVTWGLGHLVTLADPEDYDPKYKEWKMEDLPMMPDQFRLEVIKQTGKQYRVVKAQIHRSDVGEIIIATDAGREGELVARLILEKAGNKKPIKRLWISSVTDKAIKEGFAKIKNGHEYDNLYDAAMCRAEADWLVGINATRALTCKYNASLSCGRVQTPTLAIIARREEEIKNFVPKPYYGISAKCADPALSFTWRDEKSKSFRSFDRDRVEALFNHRKAIGEGVITEVKSVPKKTEPPQLYDLTELQREANRRFNYSAKETLNIMQRLYENHKVLTYPRTDSRYLSSDIVPSIKERLEACGVGPYRKLAGRLANQKIKTAPSFVNDKKVTDHHAIIPTEQFVQLDHMTIEERKIYDLVVRRFLAVLYPPFEYEQTEITLDLGGETLAARGKTVKAQGWKEVYENQDEEEEEQELKEQNLPVMKKGDMINGLTVTMTEGKTKPPAPFQESTLLSAMENPVSYMETKDKDMAKTLGETGGLGTVATRADIIEKLFSGFLLEKRGKDIFLTSKARQLLTLVPEDLKKPELTAEWEMKLSEIAGGKLKRAAFMKDIRQYSGELIRQIKTGEGSFHHDNLTSHKCPVCGKRMLAVKGKNNEMLVCQDRECGHREVVSRTSNARCPVCHKKLELKGKGDSQIFVCKCGYKEKLSSFKERRAKEGAGVSKRDVAKYMSEQKKEGNQPMNSAFADAFAKLNLGDNGK
(415) DNA topoisomerase 3 [Ruminococcus obeum A2-162]
2
MKSLVIAEKPSVARDIARVLHCNQKGNGILEGKEYVVTWALGHLVTLADPEEYDKKYVKWDMETLPMMPEKMKLVVIRQTSKQYQAVKDQLFRKDIGDIIIATDAGREGELVARWILDKSGCRKPIRRLWISSVTDKAIRDGFHNLKGGREYDNLYRAAVARAEADWLVGINGTRALTCRHNAQLSCGRVQTPTLAIIARREEEIRKFQPEEYYGVTLQAGGIQWTWKDTRSGSYRTFQKDRAEDIRKNISDGVLEITSVAKKPKKTYAPGLYDLTTLQREANQKYGFSAKETLNIMQRLYENHKVLTYPRTDSRYIGKDVVPTIKERLKACGTGPYRKLAGVLISKPIQTNGGFVDDKKVSDHHAIIPTEQFVQLDHMTNEERKIYDMVVRRFLSVLYPAFEYEQTSLEAKAAGQTFAANGKTVIRAGWKAVYEEGMQEEDTEDNALKDQKLPVFRQGEKIHIDSVRLTNGKTKPPAHFTEATLLAAMENPVKYMSTKDSQAAKTLGETGGLGTVATRADIIEKLFHTFLMEKRGNEIYLTSKAKQLLELVPEDLKKPELTADWEKKLSDISKGKLKQKVFLDGIREYTEEIVGEIKTGTGTFRHDNLTNKICPNCGKRLLAVNGKNSKMLVCQDRECGYRETISRTTNARCPKCHKRMEMLVKGKEETFVCACGYKEKLSSFQARRAKEGAGVNKRDVQKYLKKQQKEAAEPVNNAFAQALAGIKLD
(428) DNA topoisomerase 3 [Bacillus mycoides DSM 2048]
2
MFLNMAKSIVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKQWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIIATDAGREGELVARWIIDKVKMQKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKHFKAQTYYGIEAQTAERLKLTWQDTKGNSRSFNKEKTDAIVNKISKQNATVVDIDKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPVKSNKSFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFIARGKTILHAGWKEVYANRFEDDDASDDVKEQILPRIEKGDTLNIKLIVQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLLEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVAEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGSKADKRDVQKYMKQQNKEEEPLNNPFAEALKKLKFD
(463) DNA topoisomerase 3 [Listeria ivanovii subsp. ivanovii PAM 55]
2
MTKTLVLAEKPSVGKDIGRVLGAKQGKNGYLEGGKYVVTWALGHLVTLADPERYDPKYKNWNMEDLPMLPEKMKLEPIKQTRKQYETVKKLMNRTDITTIVIATDAGREGELVARWIIDYAKIKKPLKRLWISSVTDKAIREGFEHLKPGKAYENLYHSAVARSEADWVVGINATRALTTKYNAQLSCGRVQTPTLAMIQHREEEIRNFKPREYYGITALTEQECFTWNNGQTFDKALAEKLVKSLQGETAVITDVSMKEKKTFSPGLYDLTELQRDANNRYDFSAKETLNIMQTLYERHKILTYPRTDSRFISTDIVPTLKERLQACGVGENAKAARQISSKPIKANKSFVDNSKVSDHHAIIPTEQSVSLGDLSDKERKIYDLVVKRFLAVLSDPYTYEETSVKAKIGQEDFTVKGKVVKSLGWKSIYGETREPDQLTKMKKGDKIPVKRVNLETGKTKPPARFNEATLLSAMENPAKYMETSSKALAKTLGDTGGLGTVATRADIIEKLFNSFSLEKQGKEIQITSKGRQLLELVPEDLKSPELTARWEQKLSKIAKGELDYRKFTAEMRDYAKKAVLEIKQNDKKFRHDNITSQKCPDCGKPMLKVKGKRGTMLVCQDRECGHRESLSRTTNARCPNCHKRMEMRGEGDKQLFVCVCGYREKLSAFQERRDKQKNKNVSKTDVAKFMKKQNKQEDEPFNNPMAEALAKLKLDK
(482) DNA topoisomerase [Paenibacillus mucilaginosus KNP414]
2
MTNELQDVNNAKEAGTIHFCPERSTIRMKSLVLAEKPSVAKEIARVLGCQQKHKHYMEGPQYVVTWALGHLVTLAEPEEYDPKYKTWNLEDLPLLPSKMKLKVIRETTPQFKAISQLAQRGDLKELIIATDAGREGELVARWIMELVRWRKPYKRLWISSQTDKAIRDGFAQLKPGPAYDPLYRSAVCRAEADWLIGLNITRALTCKHNAQLAAGRVQTPTLAAMMDREAQIRSFQAKDFWMLRAQLGSFQALWRSQAHPDGRLFDKAAADTLLERLKTARSAKVSALKVSEKSEPHPLAYDLTELQRDANKRLGFTAKQTSNVLQRLYEQHKLVTYPRTDSRYLSSDMVSTLPDRLKALLGTPYGASAKGLLARPLPVTKRIVDDSKVSDHHAIIPTDERPQLQLLGADERRLYDLIVRRFLSLFFPAFRYDETAVTLDIAGESFHAKGRIVKDQGWKAVYDGSSAPSEADDDDAPEEEPSSLQSLPALQLGTELKDLRLSQQKGTTKPPGRYTEAGLLSVMEKQGLGTPATRADIIEKLLSTDTIERRMNTLQPTGKGVQLMELVVPELRSSELTASWERELERIAKGQGDPDAFMAGIRKQTEAIVRDVKNSSAEYKPHNLTHSKCPDCGSPLQDIKGKRGRMLVCSSRECNYKRAAEAQLSNKRCPQCRKKMEIHTGKAGKYAQCRPCNVIEMLNDTGGAGGRGKAGKRQQSQLAEQYSDNAKLPSALEE
(577) DNA topoisomerase 3 [Bacillus weihenstephanensis KBAB4]
2
MAKSIVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKQWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIIATDAGREGELVARWIIDKVKMQKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKHFKAQTYYGIEAQTAERLKLTWQDTKGNSRSFNKEKTDAIVNKISKQNATVVDIDKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPVKSNKSFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFIARGKTILHAGWKEVYENRFEDDDASDDVKEQILPRIEKGDTLNIKLIVQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLLEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVAEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGSKADKRDVQKYMKQQNKEEEPLNNPFAEALKKLKFD
(595) DNA topoisomerase 3 [Listeria seeligeri serovar 1/2b str. SLCC3954]
2
MTKTLVLAEKPSVGKDIGRVLGAKQGKNGYLEGGKYVVTWALGHLVTLADPERYDPKYKNWNMEDLPMLPEKMKLEPIKQTRKQYETVKKLMNRTDITTIVIATDAGREGELVARWIIDYAKIKKPLKRLWISSVTDKAIREGFEHLKPGKAYENLYHSAVARSEADWVVGINATRALTTKYNAQLSCGRVQTPTLAMIQYREEEIRNFKPREYYGIKALTDQECFTWNIGQTFDKALAEKIVNSLKGETAVITDVSMKEKKTFSPGLYDLTELQRDANNRYDFSAKETLNIMQTLYERHKILTYPRTDSRFISTDIVPTLKERLQACGVGENAKAARQISSKPIKANKSFVDNGKVSDHHAIIPTEQSVSLGDLSDKERKVYDLVVKRFLAVLSEPYIYEETSVKAKIGQEDFTLKGKVVKSLGWKSIFGEAREPDQLTKMKKGDKLPVKQINLETGKTKPPARFNEATLLSAMENPSKYMETSNKALAKTLGDTGGLGTVATRADIIEKLFNSYSLEKQGKDIQITSKGRQLLELVPEDLKSPELTARWEQKLSKIAKGELDYRKFTAEMRDYAKKAVSEIKQNDKKFRHDNITSQKCPDCGKPMLKVKGKRGTMLVCQDRECGHRESLSRTTNARCPNCHKRMEMRGEGDKQLFVCVCGYREKLSAFQERRDKQKNKNVSKTDVAKFMKKQNKQEEEPFNNPMAEALAKLKLDK
(598) DNA topoisomerase [Paenibacillus sp. JDR-2]
2
MKSLVLAEKPSVAKEIARVLGCSSKNKSYMEGPDYVVTWALGHLVTLAEPEDYDPKYKTWNLEDLPLLPGKMNLKVMRETSHQYKAVAQLCKRPDIGELIIATDAGREGELVARWIMELVHWRKPFKRLWISSQTDKAIKDGFKALKPGQQYNNLYASAVCRAEADWLIGLNVTRALTVKYNAQLAAGRVQTPTLGALIDREKEINQFQSQPYWTVSAELGAFQALWRQNDNHDGRVWDRSEAEAVIARLQGKSAKVDKLRTTQKSEPHPQAFDLTELQREANKRLGFSAKMTSNVLQKLYEQHKLVTYPRTDSRYLSSDIVPTLKGRLESVAVGPYAPLARKLLRGQLTVTKRFVDDSKVSDHHAIIPTDEYVNLSALSNDERKLYDLIVRRFIALFYPPYTYDETSVVLTVGQDKLYAKGKVQKDIGWKELYGGSDARFTADEDDEEENGRGEDKSTPEQLLPELVQGQAVQVKQSRLKELRTLPPARYTEASLLSKMEKHGLGTPATRADIIEKLLSTDTIERTQNRLVPTSKGKQLIELVVDELRSPELTAKWERELELIAHGQGDAKRFMAGIREQANKWVTAVKNETKEYKPHNLTHSRCPECGKLLMEVKGKRGKSLVCSDRECSYRRQAEPALSNKRCPQCHKKMEIHNGKAGKYAQCRPCNVIEMLGDKQGGRVNKHQQKKMIEQYSDNVSLSNSLADALKAAMNKQDND
(613) DNA topoisomerase 3 [Clostridium novyi NT]
2
MGKILILAEKPSVGRDIARVLNCKKGGNGFLEGDKYIVTWALGHLVTLADPEAYDNKYKSWNIEDLPMIPKHLKLVVIKKSGKQFNTVKAQMNRKDVGEIVIATDAGREGELVARWIIEKAHIKKPIKRLWISSVTDKAIKDGFKNLKDGREYNNLYKSAIARAEADWLVGINATRALTCKYNAQLSCGRVQTPTIAMIAQREEEIKNFKPKTYYGIEAKSDKLKLVWQDSRSNDIKTFNKDKCENIIKNIKNKDAKVVEVNKVKKKKFSPQLYDLTELQRDANKIFNFSAKETLSIMQRLYENHKVLTYPRTDSRYLTEDVVDTIKDRLKACGVGVYGKYANKLLKGTIKGNKSFVDNTKVSDHHAIIPTEQKFALASLSDNERKIYDLVVKRFFAVLYPPFEYEKTTIKAKIGEENFIAKGKVVLANGWKEVYSNDFEDDMEDELKEQILPSINKGDSIKINSISKTTGETKPPKPFNEATLLSAMENPVKYMSGESKELKKTIGETGGIGTVATRADIIEKLFNTFLIEKRGKDIFITSKGKQLLDLVPEELKSPALTAEWEQKLTAISKGKLNKDKFLSEIKDYSKDTVNEIKNSKEKFKHDNMTRVKCPECGKYMLEVNGKKGKILVCQDRECGYRKGISRISNARCPECHKKLELRGEGEGQIFVCKCGYREKLSAFKERKKKDSGKVSKREVNKYLRQQQKENDEPFNNPFAEAFKKLGLK
(714) DNA topoisomerase 3 [Alkaliphilus oremlandii OhILAs]
2
MYHHRIERIVNMNKKLVLAEKPSVGRDLARVLNCNKKGNGYLEGQEYIVTWALGHLVTLADPENYSDRYKSWKIEDLPILPSDLKLVVIKKTGKQFQTIKEQMHRKDVNEIIIATDAGREGELVARWIIEKAKVQKPIQRLWISSVTDNAIKDGFKKLKNGKDYEKLYQSAVARAEVDWIVGINATRALTCKYNAQLSCGRVQTPTLAIIAQREAEIQNFKSRTFYGMEAMSPHLKLTWQDRKTKDIRSFEKEKITSILNAIKNKDGYVMDVEKKYKKSYAPKLYDLTELQRDANRIFGYSAKETLGIMQQLYENYKILTYPRTDSRYITSDIVPTLKDRIKACGVGPYKLAANKVLQGSIKGNSSFVDDGKVSDHHAIIPTEQFVQLSSLSDKERKVYDLVVKRFLAVLYPPFEYEETFIRAKIGEEVFIAKGKNVIHQGWKEVYGNMDEDESGNEDISEQLLPRVNKGDVLKISSITQTTGQTKPPAPFNEGTLLSAMENPVKYMKDAHKDLIKTIGETGGLGTVATRADIIEKLFSTFLIEKRGNDIWITSKGKQLLELVPEDLKSPALTADWEQKLGAISKGDLHRDHFVKEMKAYTKTVVDEIKNSDETFKHDNLTRNKCPECGKYMLEVKGKRGKMLVCQSRECGYRKGVTQNTNARCPNCHKKLELRGEGEGQIFVCSCGHREKLATFKERKKQEGSKVSKKEVVKYMNQQKKENDGFANTALADALSKLKF
(748) DNA topoisomerase 3 [Clostridium cellulolyticum H10]
2
MGFTLILAEKPSVARDLAKVLNCGQNANGYIMGKKYIVTWALGHLVTLADPEAYGNKYKTWNLEDLPMLPNKMELVVIKQTAKQYGVVRGLLNRADVDELVIATDSGREGELVARWIIMKAGFKKPIKRLWISSQTDKAIKEGFAKLRPSKEYDNLYYSAQSRAEADWLIGLNVTRALTCKYNAQLSAGRVQTPTLAMIVEREEEIRKFRPKDYWTISAQFNGFTVQWQDSRNNQTRTFNKEEADGIVAKITGQMGEVVEVKKETKKELPPLAYDLTELQRDANKKFSYSAKQTLNIMQRLYESHKLVTYPRTDSRYITDDIVPTLNERLKSIAVGPYAKLVQGVMRNKPSVTKRFVDNSKVTDHHAIIPTEQFVDLFSLNSEERNIYDLIVKRFIAVLSKPFEYEQTTVKLDIAGESFYAKGKIVKSSGWKTVYDGFGKLDEDDEDDNDQSLPDIQKGHKAKVVGPKSINGKTKPPARYTEATLLSAMEHPGKFVDNKALKEALESTSGLGTPATRADIIEKLFNTFYIERKGKEIYPTSKGTQLISLVPTDLKSPELTAKWEQQLTLISKGKVNSNVFVNDMKKYARKLVGAVIASSEQFKHDNVTREKCPECGKYLLEVNGKKGKMHICPDRECGYRKSVTVISNARCPECHKKMEIRGEGENKSFYCSCGYREKLDAFKKRKGQQVDKREVAKFMRQQEKDENINSALADALAKWKNN
(754) DNA topoisomerase 3 [Staphylococcus lugdunensis HKU09-01]
2
MKGLIMKSLILAEKPSVARDIADALHITHKKNGYIENEKYIVTWALGHLVTNAQPEHYDKRYQTWNLNDLPIIPKHMKTIVIGKTSKQFKTVKSLLLNKQVNNVIIATDAGREGELVARLILDKVGNKKPIQRLWISSVTKKAIQQGFKNLQDGRKYNHLYQAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVYERQKEIKQFKPEDYYTLHIKVAGYEFDLDSQQRFKQREDLEHIVKAIAQNNIQVTTVETKRKKSYPQALFNLTDLQQEAYRRFKMGPKETLNTLQNLYERHKLVTYPRTDSNFLTSDMVETFSERLQALLATDYKVAVKNLMKKSFNTKLNIINDKKVSDHHAIIPTEIRPDLNQLTAREQKIYMLVAERFIASLMEPYQYEMTTVKLEVAQHQFKMKENIPLQLGYKALFDTTQTEVKKQPFRQGQQYPISQTNIKKHQTTPPDYFNEGTLLKAMESPQQVIHIQDKKYAQMLKQTGGIGTVATRADIIEKLFNINAIESTDGKIKVTSKGQQILDLAPEALTSPLLTAEWEEKLTRIEKGKYNQRKFIQEMQDFTTKIVHDIKNSVQTYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKMTLFGKGKEATYRCICGYTETQRHMDERMKHKNNNKISKKEMKKYMSSDEKLENNPFKDALKNLKL
(756) DNA topoisomerase 3 [Clostridium cellulovorans 743B]
2
MSKTVVLAEKPSVGREIARVLKCTKSGNGYIEGPKYIVTWALGHLVTLADPEVYDDKYKSWRLEDLPMLPKPLKLVTIKQSGKQFNAVKEQLNRKDVDEIVIATDAGREGELVARWIIEKARVKKPMKRLWISSQTDKAILDGFRNLKPSAQYENLYRAAQCRAEADWVVGLNVTRALTCKYNAQLTAGRVQSATLAMIVSREEEIRTFVPKDYFVINAKAKGFNLQYRDKNNNSNIFEVDKVNKVLSAVRGKEANIVEVTESYKKQYSPALYDLTELQRDANRIYGYSAKQTLSIMQRLYENYKVLTYPRTDSRYLSTDIVATLPDRLRAIAVGSYSAVANEILKGKITGHKGFVDNSKVSDHHAIIPTEEKGKLALLSSEERHIYDLVVKRFLAVMLPPYEYLQTTIKADINGETFVAKGNVIKAKGWKKVYDKEATLAEDEDDKDSQTLPVVKKGDKLNVMSIDSEKHKTKPPARFNEGTLLSAMEKPQKYVSLDKVHAKTLGETGGIGTVATRADIIEKLFNMFYIEKNGKDIIPTSKGKQVIDLVPSELKSPLLTAEWELELERISKGQKDSRGFIEAMRKYAAELVDDVKGSSDKFKHDNLTGKKCPDCGKYMLEVKGKQGRMLVCQDRECGHRENLARITNARCPECKKKLELRGQGEGKIYVCPGSNCNFREKASQFEKRFDSKSDKLNKREVAKIMNKLNQEKEDPMDSPFADLMNMFKDKK
(758) DNA topoisomerase 3 [Listeria monocytogenes M7]
2
MTKTLVLAEKPSVGKDIGRVLGAKQGKNGYLEGGKYVVTWALGHLVTLADPERYDSKYKNWNMEDLPMLPEKMKLEPIKQTRKQYETVKKLMNRTDITTIVIATDAGREGELVARWIIDYAKIKKPLKRLWISSVTDKAIREGFEHLKPGKAYENLYYSAVARSEADWVVGINATRALTTKYNAQLSCGRVQTPTLAMIQYREEEIRNFKPREYYGITALTEQESFTWNNGQTFDKALAEKLVKSLQGENAVITDVSMKEKKNFSPGLYDLTELQRDANNRYDFSAKETLNIMQTLYERHKVLTYPRTDSRFISTDIVPTLKERLAACGVGENAKAARQISGKPIKANKSFVDNSKVSDHHAIIPTEQPVSLGDLSDKERKIYDLVVKRFLAVLSDPYIYEETSVKAKIGQEEFTLKGKVVKSLGWKSIYGESREPDQLTKMKKGDTIPVKRINLETGKTKPPARFNEATLLSAMENPSKYMETTSKALAKTLGETGGLGTVATRADIIEKLFNSFSLEKQGKDIQITSKGRQLLELVPEDLKSPELTARWEQKLSKIAKGELDYRKFTAEMRDYAKKAVTEIKQNDKKFRHDNITSQKCPDCGKPMLKVKGKRGTMLVCQDRECGHRESVSRTTNARCPNCHKRMEMRGEGDKQIFVCVCGHREKLSAFQQRRDKQKNKNVSKTDVAKFMKKQNKQEDEPFNNPMAEALAKLKLDK
(812) DNA topoisomerase 3 [Staphylococcus epidermidis RP62A]
2
MKSLILAEKPSVGRDIANALNLQQKSNGYIEGKQYIVTWALGHLVTNATPEQYNPSYKEWNLEDLPIIPKKMKTVVISKTNRQFKIVKSLILDKNVKEIIIATDAGREGELVARLILDKVGNKKPIKRLWISSVTKKAIQEGFKQLKNGNAYQNLYEAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQIVKSRQDEINYFKPEKYYTLSINVDGYDLNLKQQKRYKDKKELELIEHKIKHQEGKILEVKGKNKKSYAQPLFNLTDLQQEAYKHYKMGPKETLNTLQHLYERHKLVTYPRTDSNYLTDDMVDTIQERLRAILATDYKSHVRDLISESFSSKMHIFNNQKVSDHHAIIPTEVRPSIEQLSQREFKIYMLIAERFLENLMNPYLYEVLTIHAQLKDYNFVLKEIIPKQLGYKALKDQTSSHTLTHSFKEGQLFKVHRIEIHEHETKAPEYFNEGSLLKAMENPQNHIDLNDKKYAKTLKHSGGIGTVATRADIIEKLFNMNALESRDGKIKVTSKGKQILELSPSELTSPILTAQWEEKLMLIEKGKYNSQKFIQEMKNFTFKVVNKIKSSEQKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPKCKTKKNIQRKTNARCPYCKKKMTLFGKGKEAVYRCVCGHTETQSQMDKRMRDKTNGKVSRKEMKKYINKKEEIDNNPFKDALKNLKL
(828) DNA topoisomerase 3 [Bacillus cereus ATCC 10987]
2
MSKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGRAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVMEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSKFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(878) DNA topoisomerase 3 [Clostridium kluyveri DSM 555]
2
MSKILVLAEKPSVGRDLAKVLHCNKKNLGYIEGDKYVVTWALGHLVTLADPEDYDERYKSWVLEDLPMLPDKLKLVVIKQSGKQFNIVKSQMNRKDIGEIIIATDSGREGELVARWIIEKARVKKTVKRLWISSQTDKAIKEGFANLKNSSKYDNLYKAARCRAEADWVVGLNITRALTCKYNAQLTAGRVQSATLAMIVNREEEIKNFKAKDYFVINAKTKEFTLMWRDKNNNSNIYEENRVNKILAITKGKAANIIDVRESYKKQYAPALYDLTELQRDANRIFGYSAKHTLSIMQRLYENYKILTYPRTDSRYISTDIVDTLKERLKAISVGSYKIYASELLKTRINAHKGFVDNSKVSDHHAIIPTEEVLTLSLLSSEEKNIYDLVVKRFLAVMLPPFEYVQTSIITDINGENFIARGKVVKSKGWKKVYDIGNQVIEDDENENQILPELKKGDSIDIISIESRRLKTKPPARFNEGTLLSAMEKPQKYISIDKLYAKTLGETGGIGTVATRADIIEKLFNMFYVEKNGKDIIPTSKGKQLIELVPEDLKSPLLTAQWEMDLELISKGKKDPEVFIRKMREYAGTLVEDVKESSNKFKHDNITGKKCPVCGKYMLEVKGKQGRMLVCQDRECGHRENLARLTNARCPECHKKLELKGEGEKRIYVCSHCSFREKFSSFNKRFKENEGKLNKKEVSKYMKKMNGENKANINSSLAEALANIKFK
(921) DNA topoisomerase 3 [Tepidanaerobacter acetatoxydans Re1]
2
MSKTLVLAEKPSVARDIARVMNCGKNGNGYLEGQKYIITWALGHLVTLAEPEAYGNRYKSWRMEDLPILPKDLKLEIIKQSRRQFNIVKEQMNRNDVNSIVIATDAGREGELVARWIIKMANVKKPIKRLWISSVTDKAIRDGFNNLKDGKQYENLYASAVARAEADWLVGINATRALTCKHNAQLSCGRVQTPTLAMIAKREEEIQNFKPRDFYGITATVGNLKLVWQDSQTRDIRTFDKGKIDRILASLRGKNAEVIDVTKTLKKSFAPQLYDLTQLQRDANKIFGFSAKETLSIMQRLYENHKLLTYPRTDSRFITTDIVATLEDRVKACGVGPYRTAAFKIKRPIKGNKSFVDNGKVTDHHAIIPTEQPAFLDSLSENERKIYDLVVKRFLAAMYPPFEYEQTTIKAKIGTEIFIAKGKTVIALGWKEVYEGFDDESSEDENLNDGIFEQILPTMSKGDILKITSIFQTQGRTRPPAPLNEGTLLAAMENPVKYMPKDNKDLIKVIGETGGIGTVATRADIIEKLFNSFLIEKRGKDIFITSKGRQLLDLVPEELKSPALTAQWEQKLSAIAQGALKKDTFVNDMKNYAKRAVQDIKNSEDKFRHDNLTRSKCPQCGKYMLEVNGKKGKMLICQDRECGYREKLSKVTNARCPNCHKRLELHGEGEGQIFICNCGYREKLSAFNERKASEGNNKVSKRDVAKYLQKQKKDEDKPINTELADALAKLKL
(922) DNA topoisomerase 3 [Tepidanaerobacter acetatoxydans Re1]
2
MSKTLVLAEKPSVARDIARVMNCGKNGNGYLEGQKYIITWALGHLVTLAEPEAYGNRYKSWRMEDLPILPKDLKLEIIKQSRRQFNIVKEQMNRNDVNSIVIATDAGREGELVARWIIKMANVKKPIKRLWISSVTDKAIRDGFNNLKDGKQYENLYASAVARAEADWLVGINATRALTCKHNAQLSCGRVQTPTLAMIAKREEEIQNFKPRDFYGITATVGNLKLVWQDSQTRDIRTFDKGKIDRILASLRGKNAEVIDVTKTLKKSFAPQLYDLTQLQRDANKIFGFSAKETLSIMQRLYENHKLLTYPRTDSRFITTDIVATLEDRVKACGVGPYRTAAFKIKRPIKGNKSFVDNGKVTDHHAIIPTEQPAFLDSLSENERKIYDLVVKRFLAAMYPPFEYEQTTIKAKIGTEIFIAKGKTVIALGWKEVYEGFDDESSEDENLNDGIFEQILPTMSKGDILKITSIFQTQGRTRPPAPLNEGTLLAAMENPVKYMPKDNKDLIKVIGETGGIGTVATRADIIEKLFNSFLIEKRGKDIFITSKGRQLLDLVPEELKSPALTAQWEQKLSAIAQGALKKDTFVNDMKNYAKRAVQDIKNSEDKFRHDNLTRSKCPQCGKYMLEVNGKKGKMLICQDRECGYREKLSKVTNARCPNCHKRLELHGEGEGQIFICNCGYREKLSAFNERKASEGNNKVSKRDVAKYLQKQKKDEDKPINTELADALAKLKL
(931) DNA topoisomerase 3 [Bacillus pseudofirmus OF4]
2
MKKSVVLAEKPSVARDLARVLKCEKKGNGYFEGSKYIVTWALGHLVTLADPESYGDTYKSWKLEDLPMLPSKLNLVVIKKTSKQFHAVKAQLNRGDVEQVIIATDAGREGELVARWILAKAHCHKPVKRLWISSVTDKAIQEGFSQLKDGKRYEPLYDAAVARSEADWYVGLNGTRALTTKYNAQLSCGRVQTPTLAMIAKREADIQAFKPKSFDQLFITVKDSLRFQWYQKESGERRIFDDQHAKNLKEKLEGEKLTVKAVKKQKKKTLAPKLYDLTELQREANQKFGFSAKETLSTLQKLYEHHKAVTYPRTDSRYLSSDLVETLDDRLKACDVQPYRKFVSDIRKRPLKANTHFVDDRKVTDHHAIIPTEQAPAPSALSEREYKLYQLIVRRFLAVLYPAYEYEQTKIEAEACGEQFEAKGDQVLKLGWKVVYDTKEESEGLPVVKEAEEFTIKNCTLTKGETKPPARFNEGTLLSVMERPQAFMENKTEEIAETLGKTGGIGTVATRADIIEKLFQSFLIEKRGKDLFITSKGKQLLDLVPEDLRTPALTAEWEQKLEAIANGKLTKQAFISDMKQYAKSIVGSIKASDKTFRHDNITGSKCPECGKLMLEVNGKRGKMRVCQDRECGYKKNIAKVTNARCPKCKKKLELRGEGEGQTFACVCGHREKLSVFNERKKKNKHKQVSKREVSNYMKKQNKDEDFGNTALADALAKLKLDK
(976) DNA topoisomerase 3 [Staphylococcus haemolyticus JCSC1435]
2
MKSLILAEKPSVARDIAEAMNIKGKRNGYIENEKYVVTWALGHLVTNAQPEHYDKAYKEWKLEDLPIIPKRMQTVVIGKTSKQFKTVKSLILDKKVKEVIIATDAGREGELVARLILDKVHNKKPIKRLWISSVTKKAIQEGFKKLKDGREFQHLYEAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNARQQEINHFKAKKYYTLSTEIGGLTFQLSTNKQHMTMEDATQIANEIKHVEGNVDSVEKKVKKSHPKPLYNLTDLQQEAYQRYKMGPKETLNTIQNLYERHKVLTYPRTDSNYLTDDMVDTIKERLYALLATDYKSQVKSLLGQSYSSKMRIFKNHKVSDHHAIIPTEVRPDMQSLSNRESKIYMMVAERFLESLMAPHEYEAVRVNVTVGQHIFAFNEKVTRQLGYKALKMNNDNVVKKVAFQKGEKYHLQSLKVNEHETTPPDYFNEGSLLKAMENPQNYIQLKEKKHANTLRQTGGIGTVATRADIIEKLFNLNAIESRDGKIKVTSKGKQILDLAPQELTSPLLTAEWEEKLLLIEKGRYNSRHFIDEMKAFTQSIVNTIKNSEQKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPTCKTKKNVQRKTNARCPNCKKKMTLFGRGKDAVYRCVCGHTETQEQMDKRFKNKSSGKVSKKEMKKYMNNEDSLENNPFKDALKNLKL
(1090) DNA topoisomerase 3 [Bacillus thuringiensis serovar konkukian str. 97-27]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(1129) DNA topoisomerase 3 [Desulfosporosinus orientis DSM 765]
2
MGKTLVLTEKPSVGREVARILHCNQKGKGCFIGPNYVVVWALGHLVTLADPELYDEKYKDWKMEDLPMLPDKMELVVMKETAKQFGVVKNLMRSQEFSDLIIATDAGREGELVARWIIKKAGWKKPLKRLWISSLTERAIKEGFQHLKPGKEYEALYAAAECRAEADWLVGLNVTRALTCKYNAQLSAGRVQTPTLAMIVEREQEIKNFVPKDYWTINLRARGFNLRWQDSNGQTRIFAKEKAEALAAKLKGHSGEVVEVKRDAKKELPPLAYDLTELQRDANRKYGFSAKTTSSVMQQLYENHKLVTYPRTDSRYISEDMVSTLPERLKSIALGPYVNLARGILRNKPIVTKRFVDGSKVSDHHAIIPTEQPPALSRLNSEELKIYDLIVKRFLAVLSAPFEYEQTLVKVAVQKEVFTAKGKIVKKLGWRSVYEGQGTWDDDSDDGEKEAEQTLPEISRGEILSNLSVDLASGKTKPPSRHTEATLLSAMEHPGKLIGDQKLREAMEQSHGLGTPATRAEIIEKLYNSFYMSRQGKEIVPTSKGIQLIGLVPAELKSPVLTAKWEQQLTEISKGKVNSQAFLKGIRGYTIQLVSTVSGSTQTFKHDNLTRNKCPECGKYLLQVKDKKGEMLVCQDRECGYRKRLTQISNARCPECHKKLELKGDGENKFFSCVCGYREKLSVFTKRREAEKGKMNKKDVSRYLHNQKDDGPINTALADALAKFKKQQ
(1155) DNA topoisomerase 3 [Bacillus atrophaeus 1942]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKAQLTRKDVSGIVIATDAGREGELVARWIIEKAHVNKPIKRLWISSVTDKAIKDGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYFGIRAAVEGMTLTWQDKKTKQSRTFDQAVTSRLLDKLEGKSATIADLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFISNDIVPTLKDRLEGMEVKPYALYVTKILKRGVKAHKGFVNDAKVSDHHAIIPTEEPLIPSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVIADIGGETFTAKGKTVQSQGWKAVYDAYDEEDDQDEDRDQTLPALQKGDSLPVRALKETSGQTKPPARFNEGTLLSAMENPSAFMRGDEKNLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKDKDIFITSKGKQLLQLVPEDLKSPALTGEWEQKLSAIAAGKLKSSVFIKEMKAYANETVKDIKNSSQTFRHDNVTGTACPECGKMMLKVNGKRGTMLVCQDRECGSRKTIARKTNARCPNCHKKLELRGQGEGQIFACVCGHREKLSVFEKRKSKEKTGRASKRDVSSYLKQQNKDEPINNALAEQLKKLGLDK
(1172) DNA topoisomerase [Bacillus coagulans 36D1]
2
MKSLVLAEKPSVGRELARVLGCTENKKRYIEGPRYIVTWALGHLIELKMPEDYHPKYKEWRMEDLPILPDKMEIKTIRQTYPQYKAIEQLGKRSDIKDCIIATDAGREGELVARWILEKMHWRKPVKRLWISSQTDKAIKDGFKQLKPAKQYDNLYHSAVCRSEADWLIGLNVSRALTVKYNDPLSAGRVQTPTLAMVLEREREIQSFVPKKYWTIEALAGKLEVSYDHHGEKRIFDEQKANAIHAALSGQTAVVTEVIRKQKQEQQPLPYDLTELQRDANHRFGFTAKKTLNVLQNLYEQHKLVTYPRTDSKYLTKDMENMMYDRLLAVKDAYKEEVQPILSRKGKILAKRVINDAKVTDHHAIIPTDERPALSDLSADERKIYDLIVKRFLALFYPVYEYETVQFKLQAGGKTMTGRTMAVKNAGFTAVLHHEQERENTALLSIKEGKKFKLEQIRLSQHLTEAPKRYSEADILSRMEKYGLGTPATRADIIERLVSSETISRESGRLVPTPKGKQLIDLVNDELKSPELTAKWEEQLEAIARGKGNPKQFLETIRRETVRLVREIRTSDKKYRAHNLTGTKCPECGSLMKEVNGKDGKKLVCSNRECRFTKRKSPKLSNRRCPTCHKKMEIHHGKSGVYFQCRHCNIVQKADEKKKTLSKHEEKKLLQKYTKKEESFGNSLADALKAALEKE
(1294) DNA topoisomerase 3 [Clostridium beijerinckii NCIMB 8052]
2
MSKTLVLAEKPSVGRDLAKVLKCNQNKGSYIEGSKYIVTWAMGHLVGLMDPEGYDNKYKEWKMETLPMLPKHMKLTVLKKTGRQYNEVKKQLLRNDVSDIVIATDAGREGELVARWILEKSGVKKPLKRLWISSQTEKAILDGFRNLKPGAAYENLYKAAVCRAEADWLVGLNVTRALTCKYNAQLSAGRVQSPTLSMIVLREDEIRNFKPKTYYTLEGKTRGFNLAWVNKDNNSRIFDEEFANKVASKLKNSEGKIVNINEANKKKFSPALYDLTELQRDANKIWGYSAKQTLNIMQRLYENYKILTYPRTDSRYITTDIVATIPDRLKAISIGEYRIVAEELLKGKIIGNKSFVDNSKVSDHHAIIPTEQKPNLALLSSEERKIYDLVVKRFLSVMLPPFEYIQTTIEAEVQGEKLVAKGKVIKAKGWKKLYDRLEEDSDEEEIKEQVLPTVSIGNSIRVESVNIKKGETKPPARFTEATLLSAMESPHKYINVSKEAAKTLGETGGLGTVATRADIIEKLFNSFVIEKKGKEIIPTSKGKQLMELVPKDLKSPLLTAKWESQLDEISKGKRDDHSFIKEMKNYSVALVEDVKGTNNKFVHDNKTGKKCPNCGKYLLEVKGKNGVMNVCQDRECGYRESVARVTNARCPECKKKLELRGNGEGAIYVCPGSNCNFREKASQFKKRFEKNGKIDKREVNNYMKKMKKEAEEFDDNPFAALLGDIKFDK
(1311) DNA topoisomerase 3 [Syntrophobotulus glycolicus DSM 8271]
2
MGKSLVIAEKPSVGREIAKMLSCHKKDQGYFTGPKYLVTWALGHLVTLADPEKYDQRYKTWKMDDLPMLPEQMELVVIKETSKQFSVIKNLMKMPDLDELIIATDAGREGELVARWIIKKAGWRKPIKRLWISSQTERAIKEGFAALKPAKEYDHLYASAECRAQADWLIGLNVTRALTCKFSAQLSAGRVQTPTLAMVVEREKQIKSFVPKEFWTIQAFTKGFSMTWHDKTNGQSRIFDQSKADQMIKKISGHDAEITEIKKESKKELPPLAYDLTELQRDANRKYGFSAKTTSSVMQQLYEYHKIVTYPRTDSRYITEDIVSTLPERLNSIAVGPYAQFAAKILKNKITTTKRFVDQSKVSDHHAIIPTEQPVHLQKLSNEEYKIYDLIVKRFLAVLSKPFEYEQTTVKADIRGELFEVKGKIVKQNGWKEVYQGTGNWEEEQEDEEREQTLPDLHKGERIPILEVKTKAGKTKPPARYTEATLLTAMEHPGKNIENEKLREAVKQTGGLGTPATRAEIIEKLFSSFYLERNGKEIFPTSKGLQLIELVPVDLKSAELTAKWEQQLSEISKGKVKSTEFLNGIRSYARQLVSTVSENNQVFRHDNLTRNKCPECGKFLLQVKGKKGELLICQDRECGYRKGLSVSSNARCPNCHKKMDLKGEGENRIFTCTCGYREKLASFTQRKSENPGKVNKKDVQKYLNKQEDNGMINDALAQALAKLKK
(1347) DNA topoisomerase 3 [Macrococcus caseolyticus JCSC5402]
2
MKSVVLAEKPSVARDIARVLKCNQKKNGYMENDKYIVTWALGHLVTNADPEQYDAKYKQWDLNMLPIIPERMKTVVIGKTRKQFNTVKAQIERQDVNEIIIATDAGREGELVARLIIEKCKGNKPMKRLWISSVTDKAILDGFKHLKPAQAYQGLYEAAMARSEADWIVGINATRALTTKYDAQLSTGRVQTPTLQMVKIRQDAVQKFQPKTYYSIELVSGSDKFKWQSGSQIFDESKVDGLLKDIQGKQAVVQDVVSKEKKRYPGKLYDLTSLQQDAYKRFKYSAKETLNAMQSLYETHKYVTYPRTDSNYLTTDMESSLKERVASLGATPYKDQVVKLLKTHIKGGSHFINNAKVSDHHAIVPTEIRANLEALGAREKNIYLLIAERFLSNLMEPHIYNEETITVQIGKEIFTLKTETTVKAGFKALYEQSSIERHKVYHKGEVLSSVSLKKTTGETQPPAYLNEGTLLKAMENPASIFNIDKESTTTLKSAGGIGTVATRADIIEKLYNLNAIENNNGNIKVTNKGRQLLELAPDALKSPELTADWEHKLTRIEKNKYGRKQFMREMIDFTKEIIDEIKSSDEKFKHDNLTSTECPTCGKFMLEKKTRNGKMLVCQDPTCGTKKNVQRKTNVRCPECKKKLTLHGKGPKAMYSCVCGFRETQEQMDKRFNSKKTGKVSKKEINKYMKKEEPINNPFADALKNLNL
(1359) DNA topoisomerase 3 [Staphylococcus aureus subsp. aureus T0131]
2
MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSLTVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYKDQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
(1429) DNA topoisomerase 3 [Bacillus subtilis subsp. spizizenii TU-B-10]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDQYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKSQLTRKDVNQIVIATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGIRAAVDGMTLTWQDKKSKQTRTFNQDVTSRLLKDLEGKQAVIAELKKTAKKSFAPALYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSSDIVPTLKDRLEGMEVKPYAQYVSQIKKRGIKSHKGYVNDAKVSDHHAIIPTEEPLVLSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVIAEIGGETFTAKGKTVQSQGWKAVYDMADEDDEQEDDRDQTLPALQKGDALTVRMLTETNGQTKPPARFNEGTLLSAMENPSAFMQGEEKGLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKDKDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSAIAAGKLKSSVFIKDMKAYANQTVKEIKNSSQTFRHDNVTGTACPECGKMMLKVNGKRGTMLVCQDRECGSRKTIARKTNARCPNCHKKMELRGQGEGQTFACVCGHREKLSVFEKRKNKDKGRASKRDVSSYMKKQNNKEEPINNALAEQLKKLGLDK
(1431) DNA topoisomerase 3 [Bacillus amyloliquefaciens LL3]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKAQLIRKDVSEIVIATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGLRAAADQMTLTWQDKKTKQTRTFDQTVTGRLAKDLQGKPAVISELKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSADIVPTLKDRLNGMEVKPYAQYVNQILKRGVKAHKGFVNDAKVSDHHAIIPTEEPLILSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVTADIGGETFTAKGKTVQSPGWKAVYDMYEDDDDHEEDKDQTLPALQQGQRLSVSSLKETSGQTKPPARFNEGTLLSVMENPSAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKEKDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSSIAAGKLKSAVFIKDMKSYAGKTVKEIKNSSQTFRHDNISGTACPDCGKMMLKVNGKRGTMLVCQDRECGSRKTVARKTNARCPNCHKKMELRGQGEGQTFACVCGHREKLSVFEKRKAKDKSGRASKRDINSYMKKQNNDEPMNNALAEQLKKLGLDK
(1529) DNA topoisomerase 3 [Staphylococcus carnosus subsp. carnosus TM300]
2
MKSLILAEKPSVARDIANALNVTQQRNGYFENNQYIVTWALGHLVTNATPEQYDKKFKTWDLAELPIIPDHMKTVVIPKTKKQFNTVKSLMLKENVKEIIIATDAGREGELVARLILDKVHNKKPIKRLWISSITAKAIRNGFKQLKDGKAYLSLYRAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVQMRQDEIKNFRPTEYYTLEAKIAGQSFKLASQHRIKDKQKLEKLVQRLKGKQAEVVDIQSKHKKQYPAKLYSLTDLQQDAYQRYHMGAKETLNTLQNLYERHKLATYPRTDSNYLTDDMVDTFKERLQALLATEYKAQVRPLVNQKFSAKMNIINNQKVSDHHAIIPTEIRPDMNVLSQREQKLYLMIAERFIENLLPPYEYDAVKVVCKIDGESFEFQDKVTVQPGFKALKSETTPSQMPTFDKDKSYTVQGFNIQAHETTPPAYFNEGTLLKAMENPQKFFDLKDSKHSQTLKQTGGIGTVATRAGIIDKLFNMNAIEARSGQIRVTSKGRQILDLAPQELTSPLLTAEWEEKLTQIEKGKYDSCAFMKEMKNFTKDIVNEIKNSEQKYKHDNLTSTECPTCGKFMIRVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCHKKMTLFGKGKQATYRCVCGHSETQEQMDRRHKNKGKSKVSKREMKKYMGKEELDNNPFQDALKNLKL
(1581) DNA topoisomerase 3 [Solibacillus silvestris StLB046]
2
MFTMVKSLVLAEKPSVARDIANVLKCHKKGNGFLEGDKYIVTWALGHLVTLADPESYDEKYKKWDLADLPMLPERLKLTTIKQTSKQYNAVKSQLTRNDVNEIIIATDAGREGELVARWIIERAKVNKPVKRLWISSVTDKAIKEGFANLKPGKAYENLYYAAVARSEADWYIGLNASRALSTKFNAQLNTGRVQTPVVAMVAAREDEIKNFKPQTYYGIEAQTKELKLTWQDQNGNARSFDKEKIDKIVHTLDKQNAKVIDIERKPKKTFSPGLYDLTELQRDANKLFGYSAKETLNIMQKLYESHKVLTYPRTDSRYLSSDIVSTLPERLKACSVGEYRTLANKVLTKPIKASKSFVDDSKVSDHHAIIPTEEYVNFANFNDKERKIYDLVVKRFLAVLFPAHEYEQLTVQAEIGKEKFIARGKTVISAGWKEVYSNRFDDEETSEDVKEQLLPRLEKGQVLNVTLLAQTSGQTKPPARFTEATILTAMENPAKYMNTQNKALADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPNELKSPETTAQWEQKLEQIAKGKLKKDVFINEMKQHTKAIVADIKNSDKKFKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRVTNARCPQCKKKLELHGQGEGQIFVCKCGYREKLSAFEARRKKEGGGKVDKRSVQKYLKQQEKEVEPINNAFADLLKGMKFDE
(1582) DNA topoisomerase 3 [Bacillus pumilus SAFR-032]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGFLEGDQYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVMKKTGKQFQAVKAQLARKDVKDIVIATDAGREGELVARWILEKAHVKKPLKRLWISSVTDKAIQEGFKRLKDGKEYDNLYRSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTIAMIFKREEDIQQFQPKPFYGLTAQVDGLTLTWQDAKTKQNRTFQENVIKERLAACKGKPAVVDALKKTAKKAFAPGLYDLTELQRDAHKRYGFSAKETLSTLQRLYEQHKLVTYPRTDSRFISADIVPTLKDRLKGMNVRPYAQHVNRILQSGVKAHKGFVNDAKVSDHHAIIPTEEELYPGVLSDKERKLYDLIAKRFLAVLMNPFEYEETTVITKIGSETFTAKGKTVQAAGWKAVYDDSYEEEESAEADQHLPLLSEGQSLDVRQLKETRGETKPPARFNEATLLSAMENPAAFMQNEEKDLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKGKDIFITSKGKQLLSLVPEDLKSPALTAEWEQKLSKIAKGQLKASQFMSEMKSYAKQAVSEIKQTNQTFKHDNVTGTHCPDCGKLMLKVNGKHGTMLVCQDRECGHRKNVAKKTNARCPNCHKKLELRGEGDGKIFACVCGHREKLSVFEKRKSQSNQKKASKHDVSKYMKKQKKVEEPINNALAEQLKKLKLDQ
(1608) DNA topoisomerase 3 [Bacillus pseudomycoides DSM 12442]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGNKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLIRKDVTEIIVATDAGREGELVARWIIDKVKINKPIKRLWISSVTDKAIKDGFANLKPGKAYENLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAIIAGREDEIKNFKAQTYYGIEAQTTDKLKLTWQDGKGNGRSFDKAKIDTIVKKLDKQNATVTEIEKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKILNKPIKSTKAFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFVARGKTILHSGWKEVYENRFEDDDAVEDLKEQILPRIEKGDTLSVKLIAQTSGQTKPPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTAEWEQKLEAIAKGKLKKEIFISEMKNYTKEIVAEIKSSDKKYKHENISTKTCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGDGQIFACKCGYREKLSTFQERRKKESGNKADKRYVQKYMKQQQKEEEEPLNNALAEALKKLKFE
(1618) DNA topoisomerase 3 [Clostridium acetobutylicum ATCC 824]
2
MGKILVLAEKPSVARDLAKVLKANINKKTHLEGNKYVVIWALGHLVSLADPESYGEKYKKWSMDTLPMLPKNMKLSVLKNTSKHFYDIKKVMERKDLDELVIATDAGREGELVARWIIEMAKWKKPIKRLWISSQTDRAVRDGFAHLRDGRDYENLYKSAKCRSEADWFVGLNVTRALTCKYNAQLSAGRVQTPTLYMIVSREEEIRKFKPKDYYTIEGKVKSFSMNWHDKSGDFKIFNKERAEKIEALVKGSKGKIVDVSESKKKKYSPALYDLTELQRDANRFFGFSAKETLSIMQRLYENHKLLTYPRTDSRYIPHDVVATLPDRLRAISIGKYSKFAAEILRSKINVHKGFVDDSKVTDHYAIIPTEERPALGALSNEEFKIYDLVVKRFLSIMLPPFEYIQTTVKAEVAGEIFIAKGKVVKSKGWKEVYDKTEDFEEKSELKDQMLPEMNKGEDITFSTVSIKKGQTKPPSRFTEATLLSAMENPQRYVSMDKISAKTLGETGGLGTVATRADIIEKLYKTFYIEKKGNEIVPTSKGKQLVNLVPSDLKSPLLTAKWEGQLDAISKGKLNGVSFVNEIKGYASKLVDDVKGSKDTFKYDNLTGTKCPECGKYMLQVNGKKGRMLVCQDRECGHRENLAMFTNVRCPECHKKLELRGEGEGRIYVCPNCSFREKYSSFQKRFKGNNNKVNKREVSNYMKKMKKEAEAPINNAFADLMSMFKDKN
(1622) DNA topoisomerase 3 [Brevibacillus brevis NBRC 100599]
2
MSKTVVLAEKPSVGRDIAKVLQCHKKGNGFFEGDKYIVTWALGHLVTLADPEAYGQQFGSWRIEDLPIMPSPLRLVVIKESNRQFQVVKQQLRRNDVGQIVIATDAGREGELVARWILELVHVNKPIKRLWISSVTDKAIREGFRNLKDGKNYENLFASAAARAEADWLVGINATRALTCKHNAQLSCGRVQTPTLAIVATREEEIRRFTPKPFYGLSAVAQGPIQLQWQDQQTKDFKTFSKEKADQLIAALKQEKNAEVIEITRAHKKTYAPQLYDLTELQRDANRMFGYSPKQTLSIMQGLYEHHKAVTYPRTDSRYLSADIVETLPDRIKAVQMKPYAPLAARILRAPIKANKSFVDDSKVSDHHAIIPTEQAVFLGDLSDKERKIFDLIVKRFLAVLLPAFEYEQTTIQAKIGNETFLAKGKTVLSQGWREAYDHDVEEDDAKDGVKEQILPSLAKGDRLQIQSISQTKGETKPPEPFTEASLLSAMENPAKYMANESKDLIKTIGETGGLGTVATRADVIEKLFNSFLLEKRGKHIFVTAKAKQLLELVPDEMQSPTLTAQWEQKLGAIAKGSLNKRAFIEEMKTYAKEVVQQIKNSDQTFRHDNLTRSRCPECNKFLLEVNGKRGKMQVCQDRECGYRKSIAKQTNARCPKCHKRLELRGEGEGQTFVCGCGHKEKLKTFQERRDKEKGSKVSKKEVSKYLKGQDKEPDEGINSALKDALSKLKFD
(1648) DNA topoisomerase 3 [Eubacterium limosum KIST612]
2
MSQNKTLVLAEKPSVGKDIARVLKCKNGQNGYLENDRYIVTWALGHLVSLADPEAYGEKYQNWNMESLPMLPEHMKLTVLKGSGKQYKIVSSLLGRSEVKDIVIATDAGREGELVARWILDKAHCHKPIRRLWISSVTDKAISEGFKNLKPGTEFNNLYRAAQCRAEGDWLVGLNITRALTVKYNAQLSAGRVQSATLNMIVEREEAIKNFKPKPYYNILAKTPQFTLTWQGQHGKNINSKETAEKILQKMKGKSAVIKDISKKPKKSTSPGLYDLTELQRDANRLFGMSPKETLNIMQRLYESHKILTYPRTDSKYLTQDIVPTLSERLKTISIGPYKAAVSEILKLGIHTNKSFVDDRKVSDHHAIIPTEQRVILANLSTDERKIYDLVIKRFLSVFLPPYEYLQTTVTADIAGEALTAKGREIITLGYKKVYENQSEEDDDEDNEDQQLPSLKKGNALAVSQISLKELETKPPARFTEATLLSAMENPQKVVKVDAKAAKTLGETGGIGTVATRADIIEKLYKMFVIEKKGNSLYPTSKGKQLIDLVPADLKSPLMTAKWERQLELISKGKSDPEAFIADIKTYTTELVNDVKNSNEKFVHDNKSGQKCPECGKNLLEVKGKYGMMLVCQDRTCGYRENVSKNTNVRCPECHVKLEIRGKGDGALYFCKRCGFREKVSSFNKKHFDGNRKNSKREAQNYMRKMKKENQEAVNNPFAEALAKLKESE
(1667) DNA topoisomerase 3 [Desulfitobacterium hafniense DCB-2]
2
MGKSLVLTEKPSVGRDIAKLLGCNQKGNGCFIGSRYIVTWALGHLVTLADPEAYGEKYKQWRLEDLPMLPKDMELVVIKETSKQYAAVKQLLRQPDVEELIIATDAGREGELVARWIIGKAGWKKPIKRLWISSQTDKAIREGFNNLKPGKAYESLYAAAECRAQADWYVGLNVTRALTCKYNAQLSAGRVQTPTLALVVEREKEIQNFVPKGYWTINARVQGFSLSWQDKGNGQNRMFDQRKAEQLVQKLRGHKGQVAEIKKEAKREQPPQAYDLTELQRDANRKYGFSAKQTSSIMQQLYEQHKLVTYPRTDSRYLSEDIVPTLPERLKTIAVGPYSELARRVLRTKITPTKRLVDNSKVTDHHAIIPTEQTVFLNKLSPEEAKIYDLIVRRFIAVLSPAFEYEQTTVKVEIQGELFTAKGKIVKQKGWRSVYEGREAADEEADHEEQEQNLPDLQPKQTLEVLDLKLLPGKTKPPKRYTEATLLSAMEHPGQRVNDEALRETLEKTSGLGTPATRADIIEKLFSSFYMERNGKEIVPTSKGIQLIGLVPSELKSPELTAKWEQQLSEISKGREDRQRFIQGIKSYATQLVSEVSGSGRTYRHDNMTRAKCPECGKFLLQVKGKRGEMLVCQDRECGYRQGLSVQSNARCPQCHKKMKLQGEGEHKIFTCACGYREKLSAFNKRREQEGSKGSYNKREVNHYLQKQEKDAPLNTALADALAKLNLPK
(1707) DNA topoisomerase 3 [Desulfotomaculum reducens MI-1]
2
MHKSLVLAEKPSVARDIARVLNCYKKGNGYLEGDKYIVTWALGHLVTLADPEVYDEKYKSWRLEDLPMLPSPLKLVVIRQSSKQFQIVREQMNRKDLREIIIATDAGREGELVARWIIEKARVVKPLKRLWISSVTDKAIQDGFKKLRDGKEYQNLYAAAVARAEADWFVGINASRALTCKFNAQLSCGRVQTPTLAIIAKREEEIRNFRPKTFYGITVVTDQLKLTWQDRQSKDIKTFHKEHCDQVLSLLNQKTAEVIEVEKTAKKSYSPQLYDLTELQRDANKFFGYSARETLSIMQRLYEHYKVLTYPRTDSRYLSSDMVDTLAERLKACSDQPYTKLAYKILKNPIKPSKSFVDDNKVSDHHAIIPTEQPVTVSTFSDKERKIYDLVVRRFLAVLYPPFAYEQTTIKAKMGEELFIARGKVVIAQGWKEVYQHDLEEEEPKDSLSEQTLPVIKRGDCLKVRSLTQTKGETKPPEPFTEGTLLSAMENPAKYMSQDNKELIKTLDKTGGLGTVATRADIIEKLFNSFLIEKKGKHIAITSKGKQLLELVPEGLRSPALTARWEKELEFIAKGILNKSQFINEIKKYATTVVHEIKESENRFRHDNLTGTKCPECGKRMLEVNGKKGKMLVCQDRECGYRKGLSKVTNARCPECHKRLELHGEGEGQIFVCKCGYREKLTTFHERRKNEKGSNISKKDVNKYLRNQETKDDFLNNPLAEALAKLKLKS
(1746) DNA topoisomerase 3 [Desulfotomaculum acetoxidans DSM 771]
2
MKSLVLAEKPSVAREIARILNCTIKGKGYLEGNKYIVTWALGHLVTLAEPEDYDEKYKTWRTEDLPMLPAEMKTVVIKKTGPQFHIVSKLMKRPDVRELIIATDAGREGELVARWIMKQARCQKPFKRLWISSLTDEAIREGFTRLRPGTEYNNLYDSAICRAEADWLIGLNVTRALTVKYNAQLSAGRVQTPTLAMLVSREKEIKRFVPTDFWTVKANLGKFQAEWRDKSGKHNRFSDCLQAETIVNKVKEKSGEVIDLITQEKSEQPPLAYDLTELQRDANKKFGYTAQKTLAGLQMLYERHKLVTYPRTDSRYLTSDMVPTLMPRLKAVSGGYFAELVKPLTAKPLPINKRLVDNSKVTDHHAIIPTTERANLAALTAEEKNIYDLIVRRFIAVFYPAYSYKQTTVIVLIAGEHFHASGKVVTNPGWKAVYNNESREKDTGYDDTPEQNLPPLKKGDKVKVLSCKSVKGQTKPPARYTEASLLSAMEHPGKFIEDEILKESVKESGLGTPATRAEIIEKIISSNYVERRGKELIPTAKGIQLVELVPPELKQADLTAKWEQQLHDIAMGKSKRTKFISGIREHAEKIVTTVLNSSSTFKPDNVTGNKCPKCRKFLLSVKTKRGSNLVCPDRSCGHRQVEKETSNRPCPQCKKRRMEIREGKGGKIIVCTHCRYQEKYVLQPKREAKVNIKAYSDSAPLVTNLSILANFKFNGAKEKSD
(1772) DNA topoisomerase 3 [Clostridium lentocellum DSM 5427]
2
MGKILVFAEKPSVGKDIARVLKCTQKQNGFFEGPKYVVTWAMGHLVGLSDPEAYGNQYKTWSMETLPMLPERMKLTVLKGTGKQFQIVKSLMLRKDIDEIIIATDAGREGELVARWTIDKVGVKKPIKRLWISSVTDKAISEGFKNLKPGKDYENLYKAAVCRAEGDWLVGLNVTRALTCKFNAQLSAGRVQSATLAMIVAREEAIKNFQPKPYFTLSAKCKGIQLAYKGKKGDRFFDEKQIVTLIGKLEGSKAQVTEYKETSKKQYAPALYDLTELQRDANKRFGFSPKETLSVMQRLYENYKVLTYPRTDSRFLSEDIVPTLKERINAIAIGPYKVGAREVLKNGIKSSKHFVDNSKVSDHHAIIPTEESPDLSKLNSDERKIYDLVVKRFLSVLLPPMAYNEGVLEVSSEGECFVAKGKKVIEPGWKMLYEIEADEDEDEVVQSLPEVKKGETVVLEQFFKTKQMTKAPSRFTEATLLSAMEKPHQYVEVDQKAAKTLGETGGIGTVATRADIIEKLYNMFYIEKSGKEIVPTSKGKQLIELVPVDLKSPLLTAEWEMALEQISKGKQDPKAFMKKIRVYSEELVQSVKGSGEKYIHDNLTGKRCPECNKLMLEVKGKHGKLYVCQDRNCGYRENISRFTQTRCPNCHKKLELRGEGEGQIYVCTTCTFREKLSVFNKKYRSESKKVDKKSVQKYLKEQTKKEEGNFAFAEAFAKLNK
(1791) DNA topoisomerase 3 [Staphylococcus pseudintermedius HKU10-03]
2
MSKALILAEKPSVGRDIANALNVGSRKEGYFENHQYIVTWALGHLVTNATPEQYDKKYQQWVLEDLPIIPKQMKSVVISKTRKQFNTIQNLMKRSDVKELIIATDAGREGELVARLIIEKAHVKKPIKRLWISSVTPKAIKEGFKKLKDGRAYQHLYEAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVAMRQEQIKNFKPQQYYTLEAEVNGVTMTYQHDGRVYQKEKLETIVNTLQNKQAQVNSVHEKEKKVYPQPLFNLTDLQQAAYQKYHLGAKQTLNTLQQLYERHKLVTYPRTDSNYLTTDMVDTLKERVQATMGTDLMPYAREILKQPFAKKLSFVNNQKVSDHHAIIPTEVRANVASLSPNEQKIYTMIAQRYLEVLMPPYRYRAQHVEVNIGKHVFTYQSQVPIELGFKKLQQDRAQTERAVSFKQGETFDVGRLHIVAHETTPPAYFNEGTLLKAMERPDKFFDLKDKKSAQTLKSTGGIGTVATRADIIDKLFNVNAIESHDGKIKVTSKGKQILDLAPPALTSPRLTAEWEDKLMKIEKGQYKAHQFMQEMKQFTHEIIHTIKSSEQKYKHDNLTSAQCPTCGKFMLRVNTKNGSMLVCQDPSCKTKKDVKTKTNARCPQCKKRLTKFGTGKKATYRCVCGYTETQEHMDQRFKNKGKDKVSKREMKKYMKEDELENNPFKDALKGLNL
(1822) DNA topoisomerase 3 [Bacillus cellulosilyticus DSM 2522]
2
MKKSVVIAEKPSVARDIARVLKCNKKGNGFIEGDKYIITWALGHLVTLADPEAYDQKYKSWKIEDLPMIPNHLKLVVIKKTSKQFHAVKSQLHRSDVGDIIIATDAGREGELVARWIIEKAKISKPTKRLWISSVTDKAIKEGFQQLKNAKAYENLYESAVARSEADWYIGLNATRALTCKYNAQLSSGRVQTPTLAIISQREEEIRSFRPKAFYGITAKTEENLSLSWQDKRSKDFRSFSKDNITNILSNIKGNNATVVEVSKKNKKNFAPQLYDLTELQRDANKAFHYSAKETLSIMQRLYEQHKVLTYPRTDSRYISDDIVDTLKDRVIACGKSYSEYSKLANKIVQKPLQANKSFVDNTKVSDHHAIIPTEEVANIAMFSDKERKIYDLVVKRFLAVLSPPFEYEQTTIVAEIASETFIARGKKVNSLGWKEVYGNVIEDEESDDVKEQVIPQIVKGDTLTITKVSQTEGETKPPARFNEATLLSAMENPAKYIVGETKELAKTLEKTGGLGTVATRADIIEKLFNSFLIEKKEKDIHLTSKGKQLLDLVPSDLKSPALTGEWEQKLEAIAKGNLKKNDFINDMKEYAKTVVHEIKNSDKKFKHNNMTGTKCPECGKNMLEVNSKKGKMHICQDRECGHRKNISKVTNARCPKCKKKLELRGQGEGQVFACKCGHKEKLATFNERKKKEKNTKLSKREVNNFMKKQNKQQDDEPFNPALADALAKLKLK
(1855) DNA topoisomerase 3 [Lysinibacillus sphaericus C3-41]
2
MLYMAKSLVLAEKPSVARDIANVLKCHKKGNGYIEGDKYIVTWALGHLVTLADPESYDEKYKKWNLEDLPMLPERLKLTTIKQTSKQYNAVKSQLTRNDVNEIIIATDAGREGELVARWIIDRAKVNKPIKRLWISSVTDKAIKDGFANLKPGKNYDNLYQAAVARSEADWYLGLNSSRALSTKFNAQLNTGRVQTPVVAMVAAREDEIKNFKAQTFYGIEAQTKELKLTWQDASGNSRSFSKEKVDAIVNSLDKQDAKVIEIERKPKKSFSPGLYDLTELQRDANKIFGYSAKETLNIMQKLYESHKVLTYPRTDSRYLSSDIVSTLPERLKACGIGEYRTLANKVLSKPIKANKSFVDDSKVSDHHAIIPTEEYVNFANFTDKERKIYDLVVKRFLAVLFPAYEYEQLTVQGQIGNEKFIARGKTVISAGWKEVYSNRFDDEESSEDVKEQLLPRLEKGQVLKVNLITQTSGQTKPPARFTEATLLSAMENPTKYMNTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPNELKSPETTAEWEQKLELIAKGKLKKETFINEMKQHTKEIVADIKNSDKRFKHDNISTKTCPDCGKPMLEVNGKKGKILVCQDRECGHRKNVSRVTNARCPQCKKKLELRGEGDGQIFVCKCGYREKLSAFEARRKKEGGGKVDKRSVQKYMKQQEKEAEPLNNAFADLLKGFNVDK
(1879) DNA topoisomerase 3 [Peptoclostridium difficile 630]
2
MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGHLVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVIATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSAIARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLELIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPALYDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIKAVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYNLVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESIPNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSFLMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKDYSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTISQVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYLKNQNKNQETFNNPFAEALAKLKNK
Taxa distribution
Family tree
2