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Family 4
Informations
Name
4
# topoisomerases
64
Sub-families
No subfamilies.
Topoisomerases
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Name
Family
Sequence
(40) DNA topoisomerase [Serratia sp. AS12]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
(50) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILPGEKTESLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVVATLQKDGIGFRVKWLPAPDDCDEEKRCIKEDIAHSVVQCCQEAQNAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHPFDMTKLTADELKVYQLIRQYYLAQFLPAQETDVTDVTFTIGGQVFQATGRVSVVTGWKALFADEKQAQDQDGNTALPVLKKAETCPVIRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(53) DNA topoisomerase [Acidovorax sp. JS42]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYRGPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDASTDDAGRCLQQPVAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRAQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETIARSQVLPALREGLACQVAEAEVKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCKGTLPVETGTSKRGASRPRKSGRKGS
(56) DNA topoisomerase [Pseudomonas brassicacearum subsp. brassicacearum NFM421]
4
MRLFLCEKPSQGKDIARVLGALRRGNGCYNGPGISVTWCIGHLVEAAPPEAYDERFKRWSLDQLPIVPTNWRVDVKADTAAQYKVVKQLLAKTTELVIATDADREGEMIAREILELCHYQGSIRRLWLSALNEASIRKALTGLRPADETERLYHSALARSRADWLVGMNMSRLFTLLAQRSGHHGVLSVGRVQTPTLRLVVDRDREIERFVPMHYWGIDVHLSYQEQLFLAQWVAPDCATDDAGRCIRQAMAQQALQSVRQAQRAQVLDMQMDRIREAPPLPFDLGTLQEVCSRRFGLGVQQTLEIAQSLYETHKATTYPRSDSGYLPESMWDEASTVLDALIISDPSVEALVQSVNRQQRSRAWNDSKVSAHHGIIPTLEPFQIEALSEKERAVYELIRAHYLAQFLPHHEYDRSCALFTCGGHTLRAHGKQIVASGWHRALAPDSTTSDDDSAQRNQILPPLSTGSDCNVSQVELRTLKTQAPKALTQGELIKAMKGVAKLVTDPRLKRTLKETTGIGTEATRANIISGLLNRGYLYMKGRSVRASDAAFTLIDAVPAAIADPATTAIWEQAFDMIENGQMTLDCFIAKQTAWITQLVEHYRTTTLLIHTPGGPNCPLCGASMRQRQGKHGSFWSCSRYPECKGALPVVTKTTLAPRRRKPRHSKPKGY
(59) DNA topoisomerase [Azotobacter vinelandii DJ]
4
MATMRLFLCEKPSQAKDIAKVLQATRRGDGCWLGPDLAVTWCIGHLLETAPPDAYDARYKRWDLSDLPIVPEHWKMLVKPKTASQYKVIKRLLGECRELIIATDADREGEMIARELVEHCRYRGPIRRLWLSALDDASIRKALAALKPGTETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLSVGRVQTPTLRLVVDRDRSIADFVPVPWWAIEVQLLAEGTPFTAQWRAPEDACDDQGRCLKQELAQQAAQDMRHAGSARLVALKTERIREMPPLPFDLGTLQEICSKKLGLGAQETLDIAQALYETHKVITYPRSDCGYLPQSQHGEAPAILAALERTDPALAGLMHHIDPRRRSRAWNDARVGAHHGIIPTAAAQSLDRLVGKQCAVYTLIRARYLAQFLPNHEYDRTQADFDCAGHALRAVGKRIVEPGWRRALPEALTPAKGRETPPSQELPALREGQDCAVAEVTLKDLWTQPPKPYTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQALIERGYLLKQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMSLEAFVAKQSAWMSKLIERCAGLRLTISGPAAPVGRGAGPWKKKRKAGKPGAGGRRRARPAAPP
(76) DNA topoisomerase [Alicycliphilus denitrificans BC]
4
MRVFLCEKPSQGKDIARVLGAGQRSNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPIVPERWRVEPKVATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAADVLLSHAGQSFTASWIPPEGSTDAAGRCLQQPVAQQAVDRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSRQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATEPSLRPLLGQLDRNQRSRAWNDGKVTAHHGIIPTLEPAKLLAMSEKELAVYQLIRGRYLAQFLPHHEFDRTVTQLACGGQSLVAVGKQIAVIGWRQVLATPEPDAADGEEAQRSQVLPPLASGSRCGVEQVELKALRTLPPKPYTQGELVKVMKGVAKLVDDPRLKQKLKETTGIGTEATRASTIKGLLDRGYLLKKGRAIRASDAAFTLIDAVPAAIADPGMTAIWEQALDMIEAGQMTLDTFIAKQSTWVAQLVQQHRGATLSIALPPSPPCPQCGAPMRQRTGKSGAFWSCSRYPDCKGTLPVESSASKRGAPRKRRTVPKAS
(88) DNA topoisomerase [Delftia acidovorans SPH-1]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTITWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLSTEGQAFSAQWVAPDGCTDDAGRCLQQPVAQQAALQIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQLGLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEFSCGQQMLVATGKQVVVKGWRLVLAEPQADEDGDDAARSQVLPPLRGGLACQVAEVEIKALKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQLIAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESGTPKRGASRSRSSGRKGA
(148) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(149) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(150) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(204) DNA topoisomerase [Methylibium petroleiphilum PM1]
4
MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSDETLPLYFSALARSRADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQSFVASWTPPQGSADDADRCLQQPVAQQAAEFLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLNSLVKTDPSLRPLIERLDRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKALKTLPPKPYTQGELIKAMKTVAKLVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMTLDTFIEKQSVWVGQLVQQYRGATLSLKLPPAPACPQCAAPMQQRTGKSGAFWSCSRYPDCKGTLPIESPTGRRSAPRKRRAASKAS
(205) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(275) DNA topoisomerase [Pseudomonas putida S16]
4
MRLYICEKPSQARDIARVLQAHRRGDGYLQGIGVTVTWCVGHLLETAPPETYSDQFKRWSLEHLPIIPQHWQLVVKPKVAAQLKAISRLLQACAEVVIATDADREGEMIAREILERCQYQGPILRLWLSALDDASIRRALTALRPGEQTLPLYHCALARSRADWLVGINLSRLFTLLGRRAGFDGTLPVGRVQTPTLRLVVERDRAIASFVARPFWTVDVVLHADGAEFEARWQPPAAHCDDAGHCVDQAAAEQVARRLAAARSVQVERVDVERVTEGPPLPFDLGTLQEVCSAKLGLGAQETLSVAQALYETHKATTYPRSDCGYLPESMLDEVPRVLKALAAADPALAQRFKEFDPTRRSRAWNSSKVTAHHGIIPTPVVIPLDQLSERERAVYTLIRARYLAQFLPHHEYLKTQVQLRSQADQVLARGKQIQVRGWKAVIDETDASEPTEQTQRLPTLQDGASVAAHDATINTQRTQPPKPYTEGTLVKAMKTIANQVADMRLKQTLKDSIGIGTEATRAAIIQGLIDHGYLTKKKRSLAASAAAHTLIEAVPREVADPVMTALWEQALARIETGQLSVEAFLAKQSAWLTQVVRSQASLNLQLPRSKGPACPVCRSPMRQRKGRTGNFWSCVRYPDCKGTKPVKASAAPAKPKRS
(288) DNA topoisomerase [Gallibacterium anatis UMN179]
4
MKLILCEKPSQGRDIGKFIGATKRGEGYLSSPDQQTFVTWGIGHLVEQAEPQDYDESYKKWIFDNLPIIPDKWIMKVKKETAKQYKIVMGLIKKANHIVIATDPDREGEVIARELLDMANYKGKVQRLWLSALDDGSIRKALANLKSDAETKPLYAAGLARGRADWLVGMNLTRLFTLIAQKQGYQGVMSVGRVQSPTLAIVVQRDREIENFVSKPFYRLKVNLDGFCAYWQPTESVCDDEGRCIDYSVITQVQRQLSKTLKIDNIETKRKKEMPPLAFDLGTLQQTCSRLFGMGAAQVLKIAQSLYETHKATTYPRTDCGYLPESMIDEIPLVLKAVSESDPQVRNIVAKLDISLRSRVWNDSKITAHHGIIPTTQKVDLSKMSDDELKVYQLVRKHYFAQFLPLYEEDNTSVLLSGNEQTFVSKGKQVIKIGWKSLFQQDRNEDDEEQSLPSLRQGQSCNVVDSEVLTLKTTPPKHYTEGTLIAAMKNAARFVTDARLKQRLRETEGLGTEATRAEVIETLFKRGYLEKKRKEIVATSAGRSLIDGLPDIIKDPGMTALWEQALNDIASGKMLLQDFMAKQNQFISHVVKSMIGSGSVAIQVKAEKICPKCGAAMRRRKGKNGDFWGCSNYPTCTAIENIGSRKRVGKSR
(315) DNA topoisomerase [Pseudomonas fulva 12-X]
4
MRLFLCEKPSQAKDIASVLGATRRGDGCWLGNGVTVTWCIGHLLETAPPDAYDARYKRWVLDDLPIVPQQWKMRVKANTAAQFKAIKRLLGEASELVIATDADREGEMIARELLEHCRYRGPIQRLWLSALDDASIRKALAALKPGASTYNLYQSALGRSRADWLIGMNMSRLFTLLGRKSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVTLDGNGIPFTAVWRAPQDDCDEQGRCLKQEVAQRAAEAMQGAEHAVLEKLKTERMREAPPLLFDLGTLQQVCSKKLGLGAQETLDIAQKLYETDKLITYPRSDCGYLPLSQHAEAPAILAALGQADPTLREVLAHTQTQRRSRAWNDAKVSAHHGIIPTLAAGGLTRLSGRPRAVYELIRARYLAQFLPNHEYDRTQADFDCAGHDLRAVGKQIVEPGWKRALPEALAPSKGREAPAPQALPALHEGQTCAVREVTLKDQFTQPPKPFTEGDLIQAMKNVARLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLTKQGKTLAATSAAFGLIDAVPRAIADPGTTAIWEQALDMVQSGEMPLDEFVAKQSAWMARQIERCRGLQLTISGPPPGGRPAWKGKRKGASRKKAASAKRAGASAAGGRSK
(422) DNA topoisomerase [Pseudomonas syringae pv. syringae B728a]
4
MRLYLCEKPSQGKDIAAVLGAKTRGDGCIKGNGVAVTWGIGHLLETAPPDAYGEHLKNWSLDTLPILPAEWKVLVKPKTASQFKIVKQLLKQATELVIATDADREGEMIARELIEYCGYRGPIQRLWLSALNEASIRQALNTVKQGSETYPLYLSALARSRADWLIGMNFSRLFTLLGRQAGYTGVLSVGRVQTPTLRLVVDRDRDISNFIPKPFWSVEVQLWTAGQSFLAKWVADEYLVDEEGRCLDQAAAAAALAALKSSQAASTVSVDTKRGKDPAPLPFDLSTLQEVCSAKFGMGVQETLDVAQSLYETHKATTYPRTDCGYLPESMFDEVPMVLDALNRTDPSIGKTLQLIDPEQRSRAWNDKKITGPHHGIIPTLEPANLSAMSEKERKVYELIRAHFLAQFLPTHEYDRTVATFECNAVLLQAVGKRIVIPGWKVLFSASSEEEANDSGGRSQILPVLQIGTRCDVQDLHLKSLKTEPPKAYTEGTLIKAMKTIAKLVKDPRLAQKLKETTGIGTEATRAGTIQGLIDRGSLIKKGSALRATEAAFSLIDAVPPAVADPGTTAIWEQALTMIEQGTLTLDDFIARQSSWITRLVEQYKGTTLSIKVPEGPKCPLCSAKTSQRKGSSGVFWACSRYPECKGTVNIGTGKKKSPGKSAKPRAATVKSS
(474) DNA topoisomerase [Pseudomonas putida S16]
4
MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWNLADLPIIPEKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYRGPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRGIADFVPVPFWAIDVQLEHAGFGFNAQWRAPDDACDDQGRCLNQALAQQAAVDIGNAGTARAVKVTTERVREAAPLPFDLGTLQELCSKKFGLGAQETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRSDASLAPLQPYLEPQRRSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADFDCAGHALRAVGKQIVEPGWRRALPEALTPAKGREAPPAQVLPALREGQDCTVQGLQLKDLWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMTLEEFVARQSAWMGKLVERCSGMRMTISGPAAGAAPPWKKKRRGGGKGKAAAGKPRQPRKKATT
(517) DNA topoisomerase [Erwinia sp. Ejp617]
4
MRLFICEKPSQGRDLAAVLGATQRGDGFLAGSGITVTWAVGHLLETAPPEAYGQQYGKPWTLAALPIIPSPWQVVVKKETQHQFKIIERLLRQVDEVIIATDADREGEVIARELLDYCRWEGPVQRLWLSSLDELSIRAALQNLRPGGETLGMYHAGLGRARADWLTGMNLSRLYTLRAAEAGFDGVVSVGRVQSPTLALVVRRDREIAAFVPKPYWQVKAQLSAGGITFPAQWVPAKVYTDEEKRCIHQNIAQQVVQICRQSGEATVTECETKREKASPPLAFSLGTLQQAASRLWDMSPQQVLDTAQSLYEKHKATSYPRTDCGYLPESMREEIPALLDAIGRTDPECLPLLSQLDASLVSRIWNDKKITAHHGIIPTRNAFQLSALSETERQVYMLIRRNYLAQFLPLHESDITRLAFDIGGQLFRTTGRTEVVKGWKVLFGKAEEEGSAADDEAVVALPPLKKDDRCGVTGAEVVQLMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRRFIVRKSSKLLATDLGSDVIDSLPPQLTEPGMTALWEQALDEVAAGRMSLSDFLQRQTGWTRNLVSQGAQQQVSIRIPPTPPCPLCGGKTRLRKGQKGDFWSCQRYPDCKGVINIGSGKRKSPRKAKSPKPNKN
(551) DNA topoisomerase [Pectobacterium wasabiae WPP163]
4
MRLFICEKPSQARDIAAVLGATKRGQGFLSAPGITITWARGHLLETASPEVYGTQFEKPWRIDVLPVLPPVWQMVVKSESSDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYCGWRGPVFRLWLSALDESSIRAALAAIKPGSETKPLYYAGLGRSRADWLIGMNLTRLYTVKARDKGYDGLLSVGRVQTPVLAMVVNREREIATFVPKPYWQVWVALQSNGVRFSAQWVPAKMYVDEEKRCIHQDIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRLWDMSPQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQALISQLDTRFVSRIWDDKKMTAHHGIIPTRHVCDMSKMSDQEKQVYVLIRRHYLAQFFPLHEVDFTRLSLNIGGQLFQTTGRVVVVPGWKRLFSQDDGEHKEAAADEKDQSLPMLVKGDNCGVAGSEVKALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLLARNFISIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGRMTLDSFMSRQTQWICQLVSLGTQQDVVVRVPPTPACPLCGSKTRLRKGAKGAFYGCEKYPDCKGMINVPGQSKNAASKTRKKKQN
(556) DNA topoisomerase [Pectobacterium wasabiae WPP163]
4
MCEKPSQGKDIGRVLGATQRGNGCLAGSGITVTWCIGHLVEAAPPETYGEQYKRWSIEQLPIIPERWRVEVKSKTASQFNVVKNLLSKATELVIATDADREGELIAREIIELCGYHGPIQRLWLSALNDASIRKALAALRPSGETLPMYFSALARSRADWLIGMNLSRLFTVMGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTVETVLSSAGQSFTAGWLAPDTATDDAGRCLQEPIARQAAERMRIAGSAQVTSVETERLREGPPLPFDLGTLQEICSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPVVLDSLLKTDPGLRPIVDQLDRNQRSRAWNDSKVTAHHGIIPTLEPANLTAMSDKEQAVYKLIRAHYLAQFLPQHEFDRTTACLSCTGETLQAVGKQIVVIGWRQVLTEPRPDEDGETTLRSQVLPALHEGLSCQITGIDCKALKTSPPRPYTQGELVKAMKGVAKLVSDPRLKQKLKDTTGIGTEATRANIIKGLLDRGYLLKKSRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWITQLVQQYRGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDSGKHKRAMPRKRSRSSREP
(562) DNA topoisomerase [Nitrosomonas eutropha C91]
4
MRLFLCEKPSQGKDIGKVLGATQRDNGCLKGPGVIVTWCIGHLVEAAPPEAYDANLKHWSIEQLPIIPERWRIEVKPKTAAQFKVVKQLLAQATELVIATDADREGEMIAREIVELCGYRGPIQRLWLSALNDASIRKALAALKPSSETLPMYHSALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLKLVVDRDREINQFVSIPFWAIDVALSATGQSFIAQWLAPEACTDEAGRCLQESVAQQAAQQLRANGTAQVASVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMQADVPAVLDSLLRTDPALRPVMEQLDRRQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTIARLSCAGQHLQAVGKQIVIPGWRLVLVEQQAEDADDEAAPRSQVLPALNQGLSCQMNTVDLKALKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDTVGIGTEATRANIINGLLTRGYLIKKGRAIRASEAAGTLIDTVPAAIADPGTTAVWEQALDMIEAGELTHDVFTGKQSAWISQIIAQYQGTAMTIKVPQGPACPQCGSATRQRTGKNGPFWSCSRYPECKGTVPVDSATPKRSAPRKRRSASKTS
(574) DNA topoisomerase [Acidovorax sp. JS42]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYRGPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDASTDDAGRCLQQPVAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRAQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVETGTSKRGASRPRKSGRKGS
(614) DNA topoisomerase [Haemophilus somnus 129PT]
4
MKLFLCEKPSQGRDIAKVLGATQKGEGYLSTADGTIVVTWARGHLVEHFSPEQYDPALKAWRLDTLPIIPSQWQVSPKPDAKKEYKTVMTLLKKARTVVISTDIDREGETIARELLDLAGYRGHIQRLWITALDEISVRKALSRLKTNEETLPLYYAGLARSRADWLIGMNFSRMFTLLAQQQGYQGPPLSVGRVQSPTLALVVNRDKEIAHFVPTYHYALMVQVCGTNAQSFEASLLVPEQYCDEEGRCLEIKVLQQAEQQIRQAGQVCVQNVETKREKESPPLLFALSDLQAECNRLYDLGTQQVLDIAQSLYEKHKATTYPRTDCGYLPEAQLLEVPQVINSLMQSDAKLQPLRVQLNLSQKSRAWNDKKITAHHGIIPTTQPVDIAKMNENEFKVYDLIRRRYLAQFLPHFEVDKTRVRLSCGEHQCIAKGQVIVSAGWKALFRASKEEQGEKQGLPILNSGQMLKVMNTEIKSLKTTPPAHYTEGTLLTAMVNVARFVTDERLKKQLRETEGLGTEATRASIMKTLYDRGYIKKKGKSIVATDAGVMLIDNLPTVLKDPGLTALWEQALNQIAENQMSLQEFMQKQEQFVLHLIQTCGHQGIKMGNIDIKKCPQCGKPLRKMKGKNGDFLGCTGYPKCKYIESGAKRKTSAGKVTPINLSQQFANLRQAVK
(642) DNA topoisomerase [Pseudoxanthomonas spadix BD-a59]
4
MRVVLCEKPSQGKDIARVLGATQRGNGCYTGSGLGVTWGIGHLIETAPPEAYGEQYKRWALEPLPIIPQHWQVVVKAKTATQFKVVKQLLAQATDLVIATDADREGEMIARELIDYCGYRGPIQRLWLSALNDASIRKALGALKPSGETLPLYYSALARSRADWLIGMNLSRLFTVLGRQAGYSGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTIEVLLAHAGQSFVANWTPPAGCTDDAGRCLQQPVAQQADERMRAAVSAQVVSVETERMREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQSLYETHKATTYPRSDSGYLPENMLAEVPTVLDSLVKTDPSLRPLVAKLDPHQRSRAWNDAKVTAHHGIIPTLEPANLSALNDKELAVYRLIRAHYLAQFLPHHEFDRTVAQFACAGQSLTVVGKQIVVTGWRQVLAAPAPDEPDEDAQRSQVLPALHAGLSCPIGAVDLKALKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIINGLLGRGYLLKKGRAIRASDAAFTLIDAVPPAIADPGTTAVWEQALDMIEARQMTLDAFIAKQSAWVAQLVQQYRTATLSIQLPPAPACPQCGSPMRQRTGKSGAFWSCSRYPDCKGTMAIESATGGKRSAPRKRRTAPKAS
(654) DNA topoisomerase [Magnetococcus marinus MC-1]
4
MILYLCEKPSQGRDIGRVLGATSRHEGYVAGAGVCVTWCIGHLMEMVAPDGYRPEWKSWRLDTLPIIPQQWQLELTARGRKQFKVIQGLLKGVTEVVLATDADREGETIGREVLERCQYRGKISRLWLSALDDASIRKALGNLLPGEQTEPLYQAGLGRSRADWMVGMNLTRAYTLLGRQGGYAGVLSVGRVQTPTLKLVVDRDRLIENFKPVDYFEIFALHRVHSGTFIAKWVPPPKPCDAEGHCLDRTLAETVIHKVQGHSGTITKAETKRVKEPPPLPLELSTLQQEASRRWGMGAKQTLEIAQSLYEKHKAVTYPRTDCRYLPSNQFKEAPAVLQGLTTNDASLTPLVEGADAQLRSKAWNDKKITAHHAIIPTAAKINIDALSREEALLYDLIRRHYLAQFYPPFEYDRTVIDTQVAMETFHATGRVELIPGWKRVLAANQEKKEGDEDEQTLPVVRSGEAATIEGAELKQKQTKPPNRYTEGTLIQAMKSVGKLVEDARLRKILRETSGIGTEATRAAILETLIKRNLLAKQGKKSLVSMPAGRLLVDALPHSVTDPATTAVWEQTLDDIAHGGGSLETFLAKSELWLNKLIHNVHQRQQLGLNPFRGLPPSTSHTDPAQPTPRRQRRSKAEVTPTPNAAPLCPQCGGPMLQRKSPQGAFWSCAEQATCTGTRPGSPLAAHSPLMQPNPERGPLCPKCQQAPLVQRTAYRGKNSGQPFWGCQRYPQCRYTQASQTTES
(655) DNA topoisomerase [Pseudomonas syringae pv. syringae B728a]
4
MRLFLCEKPSQAKDIAAALGATRRGDGCWVGANATVTWCIGHLLETAPPDAYDARYKRWVLEDLPIVPEKWKMLVKPRTASQFKAVKRLLGEATELVIATDADREGEMIARELIEHCRYRGPIQRLWLSALDDASIRKALAALKPGADTFSLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPAPYWAIDVRLLHDNQAFIAQWRAPSDACDDQDRCLNQALAQQAAQAMRAAASARLVKLRTERIREAAPLPFDLGTLQEICSKKLGLGAQETLDIAQSLYETHKVITYPRSDCGYLPNSQHGEAAGIIAALCKADPALANLSPHLDPQRRSRAWNDSKVTAHHGIIPTAAVRGVERLSGKPRAVYTLIRARYLAQFLPNHEYDRTQADFDCAGHALRAVGKQIVEPGWKRAMPEALAPAKGREAPAPQPLPALFQGCECAVAEVILKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLTKQGKSLCAAPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQAAWMSKQVSRCVGMRMSISGPASPAGVKPPWKKKRKTTTRVAKTATTDTAAKKPRRAVRPAAKA
(704) DNA topoisomerase [Halomonas elongata DSM 2581]
4
MSRLFLCEKPTQARDIAKVLGASEKGNGCLKGRGITVTWGFGHLLEQANPEAYDPALKRWSMESLPILPTQWKLEVKPSAKKQFTVVKKLLSSASEVVIATDADREGEMIAREILEACQFSGGVSRLWLPALDEASIRKALGDIRPGESTRLLYHAALGRSRADWLVGMNLTRAFTMRAKQLGYDLLLSVGRVQTPVLKLVVDRDREIANFVPKPFWEVVAVFQAEGGTFQAKWQPADDDVLDESGRCINQSAAQAVVARCQGLPGQVTTLETTRKREAPPLAMDLGTLQQTCSKRWGYGAQQVLDIAQALYETHKATTYPRTDCRYLPLSQLDDAQQVVTALLTSDGELAPVVQSLDLTRKSRVWNDSKITAHHGIIPTTSPCDTSKMSEAEWNVYDLVRRHYLAQFLPPHEYDHTDVALEVAGERFATTGRQVQVEGWKVLFRNVQQDDAAGDEATAKTSSQALPPLQAHANVPQSSLDLVSKTTTPPKPFAEGTLIGAMKNAARFEPNPKLKARLKESAGIGTEATRAGIIETLLKRKFLTKKGRAIVATATGRQLIDALPEVVTNPGMTALWEQALDSVAAGELSLEDFMAKQQTLVERLIEQAKSATINLPQEPAKSKACPECGAPMKKRKNDYGSFWGCTKYPDCKGMVKIGSGKKRQGKGRKASNG
(727) DNA topoisomerase [Acidovorax sp. JS42]
4
MRVFLCEKPSQGKDIARVLGAGHRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGDQYKRWAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYHGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQAGYMGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAVDVLLSHAGRSFTASWIPPEGSTDAAGRCLQQPVAQQAADCIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATDPSLRPLIGQLDRNQRSRAWNDGKVTAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANTINGLIGRGYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQLVQQYRGATLSLKLPPAPACPQCGAPMQQRTGKSGAFWSCSRYPDCKGTLPIESPTGRRSAPRKRCAASKAS
(743) DNA topoisomerase [Serratia plymuthica AS9]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
(834) DNA topoisomerase [Achromobacter xylosoxidans A8]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDASADDAGRCLQQPIAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRTQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTVADLSCGQQKLVATGKQVVVKGWRLVLAEPEREGSADEDGDAPRSQVLPALRDGMACQVAGADIKALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGYIVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPACKGTLPVATGTSRRGASRPRRTSGGGCKGA
(876) DNA topoisomerase [Pasteurella multocida 36950]
4
MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKRWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAGYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMAQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVPEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLFGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKLNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKTVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSASNKSAKKSSNLNVLDQLNKLRSQL
(881) DNA topoisomerase [Haemophilus parainfluenzae T3T1]
4
MKLFLCEKPSQGNDIAKILGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKKWAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAGFRGQIKRLWLSALDDASIRKALGALKDNEETLPLYYAGLARSRADWLIGMNFSRIYTLLAQQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPEQYCDPDGLCLSAQVIQAANQQIRQLGQAKMESVETKRERQNAPLCFALSDLQSEANRLYGLGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPKIIQCLLQSDNRLQPLAGMLNLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKTQIILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDAPQALPTLKQGQICQISDSEIKTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQGLIDKGFLKKKGKSLLATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVRHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFLGCSAYPNCQHIENFDSKKNTKGAKSSKKTSSKSVSEQISSLRSLLN
(1002) DNA topoisomerase [Halothiobacillus neapolitanus c2]
4
MRVYLCEKPSQARDIAAVLGIQSKDKSSITTADGVVTWAFGHLLEQAPPDAYDDSLKRWALASLPIAPTQWKVEVKSSAKDQFKAIATLLKRATEVVIATDADREGEMIARELMAFVGFKGKVQRLWLSALDAASVKKALAALKPSAETAGLYQSALGRSRADWLVGMNLTRAFTLAGCSQGGEGVRSVGRVQTPTLSLVVARDRQIEHFKPVPYFELFGFFEAGQSFSTKWKVPEGAGDDAGRCVDQSIVDAVASKITGKTGTVSQYETKRISENPPLPFSLSTLQKTCSAKFGLGAQEVLDIAQALYETHKATTYPRSDCNFLPEEQFQEASSIVTALAKSDTEVQGIVDLLDFSRKSPAWNTKKITAHHAIIPTQTPPNMDAMSDNERRVYELIRRQYLAQFLPNYEYDRTQIGISIEGELFQTTGKIDQVTGWRVLFGKADASDDEPDDEVQTLPALTQGQTLPLSHTEIAAKQTKPPSRYTEGTLIDAMQTIGKNITDPRLKAILKENSGIGTEATRAGIIANLIERGFITKKGKQVISSDVGRQLIDALPDSVKSPALTALWEQSLEEIAEGKRELAGFEADVVKFITAIIDQIKKQHADAPAPTRPTADCPTCKAQGQAEKVYSIKKQCHYWHCKACNQWFDDAAGKPVPKAAASSSKTKPAPRKKTTARKAK
(1071) DNA topoisomerase [Herminiimonas arsenicoxydans]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAATPEAYDEQLKRWSIEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLPMYHSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIVVSLSAGVQAFTAHWVPPNACTDDAGRCLQQPVAQQAMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVTTVLDSLLKTDPSLRSIIGQLDRLQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDHTVAKLSCGGQNLAATGKQVVTPGWRQVLAEPQSEDGDGDGDTAARAQVLPALHEGLACQVADIDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGNASLSIKAPQGPTCPQCGAPTRQRSSKSGPFWSCSRYPDCKGTLPVESGSSKRAASRPRRSGRKGS
(1122) DNA topoisomerase [Pseudomonas fluorescens F113]
4
MQLYLCEKPSQAKDIAAVLGATRRGDGCWLGPGITVTWCIGHLLETAPPDAYDARYKRWVLADLPIVPAQWKMTVKPKTASQYKAVKRLLGEAKELVIATDADREGEMIARELVEHCRYRGPIRRLWLSALDEASIRKALAALKPGAETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVQLSHEGTAFTAQWRADPDACDDQERCLNQALARDAAQAMANATTARTLKVRTERLREAAPLPFDLGTLQEVCSKKLGLGAQETLDIAQSLYETYKLITYPRSDCGFLPLSQHSEAPAILAALAQADPSLAPLREHLQPQRKSRAWNDAKVSAHHGIIPTAAARNLDKLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKQIVEPGWKRALPEALAPARGREAPTPQTLPALSEGRDCAVDEVKPKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTRQAAWMSKHVARCQGMSLTISGPASPAGRGATPWKNKRKPAKRKTSGAPRKPSKAKAT
(1177) DNA topoisomerase [Pseudomonas aeruginosa NCGM2.S1]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTITWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAEGQAFAAQWVAPDDCTDDAGRCLQQPVAQQAAQQIRAAGSAQVVSVGTERVREGPPLLFDLSTLQEVCSRQVGLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLNTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSALSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEFSCGQQTLVATGKQVVVKGWRLVLAEPQADEDGDDTARSQVLPPLREGLACQVAEVEIKALKTMPAKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQLIAQYGCVSLSIKLSHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESGTPKRGASRSRSSGRKGA
(1196) DNA topoisomerase [Cupriavidus metallidurans CH34]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGSSKRGASRPRRSGRKGS
(1235) DNA topoisomerase [Pseudomonas fluorescens F113]
4
MRLFLCEKPSQGRDIAKVLGASRRGDGCLIGRETTVTWCIGHLLETAPPEAYGDQYKTWSLDHLPIIPAQWRVEVKPKTVAQFKIIKHLLSEATTVVIATDADREGEMIARELLELCNYRGSVERLWLSALNEASIRKALSSLKSSQETFPLYHSALARSRADWLIGMNLSRLFTLLGRRAGYGAVLSVGRVQTPTLRLVVERDRAIASFVSVPYWVVNAHLSSMGQQPFIASWIPPSSGRDEAGRCLQQALASQALQAISSSKTATVVSLRTEHLREAPPLPFDLSTLQEVCSRKLGLGAQETLNIAQALYETHKATSYPRSDCRYLPESMFNEVAAVFDALLRMDPALRPALGSIDQSLRSRAWNDAKVTAHHGIIPTTEPANLGRMSEQERQVYELIRSHYLAQFLPHHEFDRTEVELECSAERLTAVGKQILVQGWKGLLSDNPDDDEPSQKSQVLPALQQGRQCAVDDVELKSMRTAAPKSLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLIDRGYLLKKKRALMASATAHTLIEAVPAAVADPGMTAIWEQALDEIEAGRLSLDAFVAKQAHWITQLIANCGALTLSVPVEAGPVCPICNASMLRRKGKSGPFWSCSHYPDCKGTVPISKGIRRP
(1256) DNA topoisomerase [Serratia proteamaculans 568]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMTVKKETADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRATLQKGGIAFPASWVPAANYCDEEKRCIQQNVAQAVVQLCQQTGHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQALSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTQSGSVARLDRTFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEVVAGWKVLFQHDVSEAKEESTDTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKAQAVKFTAPPSPPCPTCSGTMRRRAGKKGSGAFWGCSNYPTCQGIINIDAKGGRKAKRYKAKSPAKNKTTKSE
(1283) DNA topoisomerase [Acidovorax citrulli AAC00-1]
4
MRVVLCEKPSQGKDIARVLGARQREAGCLAGPGIKVTWGIGHLIEAAPPEAYGEHFQRWSLETLPIVPQQWRWVVKADTASQFKVVQRLLAQASELIIATDADREGEMIARELIEYCGYRGPIQRLWLSALNDASIRKALGALRASHETLPLYHCALARSHADWLVGINLTRLFTLLGRKAGFDGVLSVGRVQTPTLKLVADRDREIAAFVPVPFWSIEVSLSAGAQAFSAHWVPPATVTDAAGRCLQQSAAQHAAAAVRTAGHAQVTGIDTERVQEGPPLPFDLSTLQEVCSRRLGLDVQETLDIAQALYETHKATTYPRTDAGYLPENMLTEVPTVIRSLLKTDPALQPLMQRLDLGQRSRAWNATKIAAHHAIIPTLEPADLSKMSEKELAVYRLIRAHYLAQFLPHYAYDRTMVRLACGGQALQASGKQVVDAGWKAAFAAPSIPGAGAETPEAETDSEAPRDQALPTLHEGMACEVRSLDLKSLYTKSPPPYTQGELVKAMKTVAKLVTDPRLKQTLRDTTGIGTEATRANIISGLLARGFLVRKGRVVRASKTAMTLIDAVPAAIADPGTTAIWEQALHMIEARTMDLDTFVSKQAAWVSQLVEQHREATLAIRVPAGPPCPLCGAATRKRTGKTGAFWSCSRYPDCKGTVAIDSAEAGRRNGPRKPRAARKLH
(1301) DNA topoisomerase [Proteus mirabilis HI4320]
4
MKLFLCEKPSQAKDIARVIGAHQRRDNFFQGNGVQVAWARGHLLEQAEPEAYGAQFAAPWRQSALPVIPEQWKMVVKKDAVSLFQTIKQLLSQATEVVIATDADREGEVIARELLEACHYRKKVQRLWLSALDEASIRQALNNLLPGEKTASLYSAGLGRARADWLIGMNMTRLFTLKARELGFGGILSVGRVQTPTLALIVRREREITHFVSKPFWRVTASLQHQGIIFQAHWRPASQYCDDEHRCIHVQAAQAVEQLCRQAGKATVCTVNETKGKALPPLPFDLGTLQQAASRRWGYSADKVLEIAQSLYEKHKATTYPRTDCGYLPVSMRADIPVVLDALSQSDPALQNVLAQLQPARISRVWNDAKITAHHAIIPTRQTPDLNAMNEAELNVYKLIRAHYLAQFLPDQEWDATEVFLDIGGQQFVAKGKVERVKGWSVLFVKHEDDPPVKEEAETGLEAGTETLPSLHEGEFCVVQEAKVVQLATSPPKPYTDGTLIAAMKNASSFITDPTLKKVLKENAGLGTEATRAGIITTLENRKLIVRQKKTLRATDTGCQLIDALPAACTDPGMTALWEQSLEQVAQGNLSLDVFMQKQISWLAHLIKKGGEMPLALDLPPMPSCPSCHGKMVLRESSKGRFWSCQRYPDCKGSVPLPEKMQGVTRGMNKRKKAVKKSITGLFT
(1302) DNA topoisomerase [Pseudomonas entomophila L48]
4
MRLFLCEKPSQAKDIAKVLGAQRRGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWSLDDLPIIPEKWKMTVKPKTASQYKAVKRLLGEARELVIATDADREGEMIARELVEHCRYRGPIQRLWLSALDDASIRKALARLLPGQETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVQLESAGNVFNAQWRAPEDACDDQGRCLKQALAQQAAHDMQAAGSARVMKIATERVRETAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETHKLITYPRSDSGYLPLSQHGEAPGILAALQRADASLAPLQPYLDPQRRSRAWNDQKVSAHHGIIPTAAASDPSRLPPKYKAVYTLIRARYLAQFLPNHEYDRTQADFDCAGHTLRAVGKQIIEPGWRRALPEALMPQKGREAPPAQVLPALREGQDCAVQGLQLKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKETTGIGTEATRASIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQNGEMSLDEFVARQSAWMGKLVQRCSGMRLTITGPAAGKAAAPWKKKRKSSGKGKVAGSGGKAAAGKPRQPRRKTAT
(1322) DNA topoisomerase [Haemophilus ducreyi 35000HP]
4
MRLFLCEKPSQGNDIAKVLGATKRGDGCLSSGNGQVFVTWGIGHLVEQLNPEQYHPEWKKWSLETLPIIPGQWQLAPKKETKKQYNIVIKLIKQASEVIIATDIDREGETIARELLELAGFKGKIQRLWLSALDDASIRKALALLKPNHETLPLYYAGLGRSRADWLIGMNFSRLFTLLAQQQGYQGKPLSVGRVQSPTLALVVNRDREIQNFVPKNHFTLSALLYSGQQNFTAQYVIPEQYCDEDGLCLSQQTIQAVNQQVQQAGVMKVESVETKREKQSAPLLFALSDLQSEANRLYGLGAQQVLDIAQSLYETHKATTYPRTDCGYLPESQLAEAPQVIKSLISSDSRLQPLTSKLNLTQKSRAWNDKKITAHHGIIPTAVKVDIGKMSEEEFRLYDLIRRRYLAQFLPVSQSDKTQIVLKCGVHTFISRGNVLIATGWKMLCGAPMTKRNGKNGQFWGCTAYPDCQHIENIGKSTARRKGTANSQNISQQIANLRKLVQ
(1370) DNA topoisomerase [Xanthomonas axonopodis pv. citri str. 306]
4
MRVVLCEKPSQGKDIARVLGAHRREAGCLGGPGITVTWGSGHLIEAAPPEAYGEHFQRWTLPIVPPRWQWVVKARSAAQFKVVKRLLGEASELIIATDADREGEMIAREMIDYCGYRGPVQRLWLSALNDASIRKAFGALRASSETLSLYHCALARSRADWLVGINLTRLFTLLGRHAGHDGVLSVGRVQTPTLKLVVDRDREIAAFVPVPFWSIDVSLSAANVPFSAHWLAPRTATDDAGRCLRQSVARHAADAIRAAGTAQVVHTETERVREGPPLPFDLSTLQEVCSRRLGLEVQETLDIAQALYETHKATTYPRTDAGYLPENMLAEVPTVIQSLVKTDPALQPLIDRLDFRQRSRAWNDAKITAHHAIIPTLEPADISAMSAKELAVYRLIRAHYLAQFLPHHEFDRTVVRFRCGGETLQAVGKRIAVPGWQHAFSAPSLPHVAADGADTEGSDEAPREQMLPVLQEGISCQVSALDLKSLSTKPPRPYTQGELVKAMKTVARLVTDPRLKQKLKDTTGIGTEATRANIISGLLSRGFLIRKGRAVRASDTAMMLIDAVPAAIADPGTTAIWEQALDMIEARQMGLESFVEKQAAWVTQLVRQHLGTTLAIRSPEGPPCPLCGAATRQRTGRSGPFWSCSRYPDCKGTAPVAPAQAGPDGQKRSRSRGARAQR
(1383) DNA topoisomerase [Edwardsiella ictaluri 93-146]
4
MQLYLCEKPSQAKDIARVLGISKRGQGFISADNITVTWAIGHLLEQASPDAYGEQFGKPWRVDVLPVLPDNWKMVVKPQTRDQFTVISKLLKQAGEVIIATDADREGEVIARELLAYCGYRGAVRRLWLSALDEASIREALAGILPGENTAKLYDAGLGRSRADWLIGMNLTRLYTLIARESGVSDVLSVGRVQTPTLAIVVNRDKEIADFVPVPWWQVQVLLEKDGVRFRATWQAAAQYCDDEKRCVNKQAANAVGQLCQQQKGATVLEVSQKRDKTPAPLCFDLGTLQLVCSRKFGMGAKETLAVAQSLYETHKATTYPRTDCGYLPTSMQKEIPEVMGSVAKSDPSVAPVLAQLDRGFVSRVWNDKKITAHHAIIPTRQAFDLSRLSADELKVYQLIRQHYFAQFLPLQESDVTDASFNIGGQLFLAKGKVNVITGWTCLFQKEIQEDPPEDDDMALPALNKGDSCIVNGASVGDKVTSPPKPFTEGTLIAAMKNAASFVSDPKLKKVLRDNAGLGTEATRAGVLETLFSRHYLEKKGKHIHATLLARELIAALPETLTSPGMTALWEQALDDIAQGKMSLDTFIQKQLQWTRHLVDKGRADTVKITAPVTPPCPVCKGLTRKRKGKNGDFWGCIRYPECNGIVAGKSGGKGRKIARGKKTVVNTEVELSASQ
(1410) DNA topoisomerase [Bordetella petrii DSM 12804]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFESVPYWAIDVSLSAGGQTFTAQWVAPDASTDDAGRCLQQPVAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMEQLDRSVRSRAWNDTKVSAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTVAELFCGQQKLVATGKQVVAKGWRLVLAEPQADEDGDGAARSQVLPALRDGMACQIAGADIKALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGYIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEGGQLTLDVFIGKQAAWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCKGTLPVATGTSRRGASRPRRTSGGGRKGS
(1420) DNA topoisomerase [Aromatoleum aromaticum EbN1]
4
MRVFLCEKPSQGKDIARVLGAGQRRNGCYSGAGIVVTWCIGHLVEAVPPEGYDERDKRWVIEQLPIIPERWRVEPKAATAAQFKIVKQLVGQATELVIATDADREGEMIAREIIELCGYRGAIQRLWLSALNDASIRKALGALKSSAETLPLYYSALARSRADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSAPFWAVEVALSHAGQPFTASWTPPEGCTDEAGRCLQQPVAQQAAERMRATGSAQVASVETERVREGPPLPFDLGTLQELCSQQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIDRLDRNQRSRAWSDAKVTAHHGIIPTLEPANLSAMNDKELAVYKLIRAHYLAQFLPHHEFDRTVAELACGGQSLLAVGKQIAVAGWRQVLASSEEGGADSDDAQRSQVLPALRAGLSCQVGHVDLKALKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIISGLLGRGYLLTKGRAVRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIEAGQMTLDAFIAKQSAWVTQLVQQYRGTTLAIKLPPSPSPSCPQCGAPMRQRTGKSGAFWSCSRYPDCKGTLPVDTSTGKRSASRKQRASPKAS
(1504) DNA topoisomerase [Burkholderia xenovorans LB400]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWSIEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSASGQSFTAQWVPPDAYTDDTGRCLQQPVAQRAAQQIRGAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTVANLACGQQKLAATGKQVVVKGWPLVLTEPQPDEDGDAAARSQVLPALREGLACLVADVDLKALKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARGYIVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSKRGASRPHRSGRQGS
(1516) DNA topoisomerase [Bordetella petrii DSM 12804]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWSIEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSASGQSFTAQWVPPDAYTDDTGRCLQQPVAQRAAQQIRGAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTVANLACGQQKLAATGKQVVVKGWPLVLTEPQPDEDGDAAARSQVLPALREGLACLVADVDLKALKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARGYIVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSKRGASRPHRSGRQGS
(1543) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGGSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILPGEQTESLWQAGLGRARADWLTGINLTRLYTLKAQEQGFGEVLSIGRVQTPTLALVVNRDNDIARFEQKPYWQVMATLQKDDISFRAKWLPAPDDGDEEKRCIREDIAQRVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGTLQQVASRQWGMGAGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDASAFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVTFTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTALPALKKEEISPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(1568) DNA topoisomerase [Xenorhabdus bovienii SS-2004]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDDCDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVTFTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTALPALKKEEICPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLLARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVTGSRKTRRGNSPD
(1569) DNA topoisomerase [Xenorhabdus bovienii SS-2004]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDDCDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVTFTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTALPALKKEEICPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLLARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVTGSRKTRRGNSPD
(1580) DNA topoisomerase [Parvibaculum lavamentivorans DS-1]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGSSKRGASRPRRSGRKGS
(1586) DNA topoisomerase [Dickeya zeae Ech1591]
4
MRLFLCEKPSQGKDIGRVLGTTQRGNGCLTGSGITVTWCIGHLVEAAPPETYGEQYKRWSIEQLPIIPECWRVEVKSKTASQFNVVKELLSKATELVIATDADREGELIAREIIELCGYRGPIQRLWLSALNDTSIRKALSVLRPSDETLPMYFSALARSRADWLIGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWAVEVVLSSAGQHFTAAWLAPDTAADNAGRCLQEPIARQATERMRVTGSAQVTSVETEHMREGPPLPFDLGTLQEVCSRQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPIVFDSLLKTDPDLRPIVDLLDRNQRSRAWNDSKVTAHHGIIPTLEPANLAAMSDKERAVYTLIRTHYLAQFLPHHEFDHTTAYLSCAGEMLQAVGKQVVLVGWRRVLTEPKPDDDGDTTSRSQVLPPLNEGLSCQITGIDCKALKTSPPRPYTQGELVKSMKSVAKLVSDPRLKQTLKDTTGIGTEATRANIIKGLLDRGYLLKKGRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIESGQLTLDVFIDKQSAWIAQLIQQYRGASLSIQMPLGPACPECGTPMHQRPGKNGAFWSCPRYPDCRGSLPIDSGKRKRTTPRKRNSSLQAS
(1616) DNA topoisomerase [Pseudomonas stutzeri A1501]
4
MTVTWCIGHLLETAPPDAYDPRYKRWVLADLPIVPERWKMLVKPKTASQFKAVKRLLGECRELVIATDADREGEMIARELVEHCRYRGPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQSGYRGVLPVGRVQTPTLRLVVDRDRSIADFIPVPFWAIDVQLLADGAAFTAQWQAPDDLCDDQGRCLDQARAQQAADAMRNAASARLLKLKTERQREAAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETHKLITYPRSDCGYLPLSQLGEARAIVAALTQADPTLAALQPHLDLSRRSRAWNDAKVGAHHGIVPTAAARGLERLAGRPRAVYELIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKRVVEPGWKRAMPEALAPARGNREAHAPQSLPALQQGQDYAVGEITLKDQQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLVRQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQSAWMSKLVERCAGLRMTISGPPVAAGRNGKPWKKKRSATPRRGSGARTRKPRAAD
(1681) DNA topoisomerase [Tolumonas auensis DSM 9187]
4
MRLFLCEKPSQGKDIGRLLGARQRGNGCLNGPGVVVTWCIGHLVEAAPPEAYDEQLKRWTIEQLPIIPQHWRVEVKPKTAAQFKVVKDLLSKATELVIATDADREGELIAREIIDLCGYRGPIQRLWLSALNDASIHAALGKLKPSGDTLPMYHSALARSRADWLVGMNLSRLFTLLGRRAGYDGVLSVGRVQTPTLRLVVDRDREIAAFVSVPFWSIEVALSCTGQTFTAQWLPPSASTDDAGRCLQEPVAQQAVQRIRAAGAAQMVSVETERMREGAPLPFDLGTLQEVCSKQFGLDVQETLEIAQSLYETHKATTYPRSDSGYLPESMHAEAPTVLDSLLKTDPSLRPIIDQLDRTQHSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAAYRLIRAHYLAQFLPPHEFDRTTARFSCGDQTLQAVGKHVVVPGWRLVLAEPQPDDAGDDAAPRSQVLPALHQGLACQVAGVDLKALKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDSVGIGTEATRANIIGGLLNRGYLIKKGRAIRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIETGQLALDTFIDKQAAWVTQLIAQYRGTSLSIKIPEGPACPQCGGATRQRSGKSGPFWSCAKYPDCKGTLPIESGKRAAPRKRRGGPKAS
(1717) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MQLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCHFTGPVRRLWLSALDETSIRQALAAILPGEKTAPLWQAGLGRARADWLTGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMATLQKDDISFRAKWLPAPDDGDEEKRCIREDIAQSVVQRCQQTQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDASAFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVTFTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTALPALKKEEISPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(1779) DNA topoisomerase [Xylella fastidiosa 9a5c]
4
MTRRSSAGRWSSCPLFRSSGGSRSNRRPPRNSKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLGLQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCTDDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGASRPRSSGRKGS
(1781) DNA topoisomerase [Thauera sp. MZ1T]
4
MRVFLCEKPSQGKDIARVLGAVQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSMPYWAVDVLLSHAGQSFTASWIPPEGSTDAAGRCLQQPVAQQAADRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIERLDRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLICAHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQLVQQYRGATLSLKLPPAPACPQCGAPMQQRTGKSGAFWSCSRYPDCKGTLPLESPTGRRSAPRKRRAASKAS
(1818) DNA topoisomerase [Pantoea ananatis PA13]
4
MRLFLCEKPSQGRDLAAVLGASRRGEGFMTGNGVTVTWAVGHLLETAPPEVYGQQYGKPWSLSALPILPSRWQVVVKKDTQDQFKVIEKLLRQADEVVIATDADREGEVIARELLDYCGWDGRILRLWFSALDELSVRAALSDLRPGQASVGMYHAGLGRSRADWLIGMNLSRLYTLRAAEAGFEGVVSVGRVQTPTLALVARRDREIAAFVPKPYWQVKATLSASGVSFQASWVPAAVYADEEKRCIHQNIAQQVAQLCRQAGVSTVTEYETKREKEAAPLAFSLGTLQRACGKMWNMSPQKVLDTAQSLYETHKATTYPRTDCGWLPKSMREEIPAVFDAMARTDPSPEFASLLSQLDRGFASRIWNDKKITAHHGIIPTRNAVQLSSLTETERQVYLLIRRNYLAQFLPLCESDATRISFDIGGQLFRTTGRTEVLKGWKVLFTKDEEDKDTAEEDIAGSLPPLSKGAQCGVTDAEVKQLMTQPPAHYTFDTLIGAMMNAAAYVTDLQLRKILKENAGLGTEATRAGIIEQLLSRRFITLKGSKLLATDLGADVIDALPPQLTDPGMTALWEQALDEVAAGRMNLNDFLQRQTAWTSTLVSQGMQQRISIRVPPSPPCPLCGSKTALRRSPKGEFRSCTRYPECKGIISLDSGRRKSPARAKSPKTKKN
(1826) DNA topoisomerase [Bordetella petrii DSM 12804]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTITWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLSTEGQAFSAQWVAPDGCTDDAGRCLQQPVAQQAALQIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQLGLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEFSCGQQMLVATGKQVVVKGWRLVLAEPQADEDGDDAARSQVLPPLRGGLACQVAEVEIKALKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQLIAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESGTPKRGASRSRSSGRKGA
(1828) DNA topoisomerase [Thioalkalivibrio sulfidophilus HL-EbGr7]
4
MRVFLCEKPSQGKDIARVLGARQRGNGCYSGSGITVTWCIGHLVEAAPPETYGEQYKQWSIEQLPILPERWRIEVKAKTAAQFKIVKQFVAQAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALTQLKPGGETLPLYFSALARSRADWLIGMNLSRLFTVLGRRSGYQGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWTIDVTLSHAGQSFAASWMPPDGTTDAAGRCLQQPVAQQAADRIRAGRESKVLSVETERVREAAPLPFDLGTLQEVCSRQLGLDVQETLDIAQSLYETHKATTYPRSDSGYLPESMLAEVPTVLDALLATDPGLRPLIDRLDRTQRSRVWNDSKITAHHGIIPTLEPANLSAMSEKELAVYALIRAHYLAQFLPHHEFDRTLVMLDCAGQSLQAVGKRVIVPGWHLALPGKGQDAADDEPAQRSQILPPLDTGARCGVQQVELKALKTLPPKPYTQGELIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAGIINGLLARGYLVKKGRAIRASDAAFTLIDAVPAAITDPGTTAIWEQALDMIEAGQMTLDTFINKQSAWVAQLVQQYRGTVLSIKLPEGPACPVCGAATRQRNGKNGAFWSCSRYPDCKGTLPAESSTGRRRASRQRRAAPKAS
(1864) DNA topoisomerase [Pseudomonas brassicacearum subsp. brassicacearum NFM421]
4
MQLYLCEKPSQAKDIAAVLGATRRGDGCWLGPGITVTWCIGHLLETAPPDAYDARYKRWVLADLPIVPAQWKMTVKPKTASQYKAVKRLLGEAKELVIATDADREGEMIARELVEHCRYRGPIRRLWLSALDEASIRKALAALKPGAETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPIAYWAIDVQLSHEGTAFTAQWRADPDACDDQERCLNQALARDAAMAMSNAASARTLKVRTERLREAAPLPFDLGTLQEVCSKKLGLGAQETLDIAQSLYETYKLITYPRSDCGFLPLSQHSEAPAILAALAQADPSLAPLREHLQPQRKSRAWNDAKVSAHHGIIPTAAARNLDKLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKQIVEPGWKRALPEALAPARGREAPAPQTLPALAEGRDCAVDEVKPKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTRQAAWMSKHVARCQGMSLTISGPASPAGRGATPWKNKRKPAKRKAGGAPRKASKAKAT
(1882) DNA topoisomerase [Serratia proteamaculans 568]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAVKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDITNFISKPYWQVRATLQKGGITFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQYLSLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILDTLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
Taxa distribution
Family tree
4