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Family 7
Informations
Name
7
# topoisomerases
197
Sub-families
No subfamilies.
Topoisomerases
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Name
Family
Sequence
(5) DNA topoisomerase [Weissella koreensis KACC 15510]
7
MRTIILAEKPTQAVAYSKAFKSSKKREGYIEVSNEYFDGETYITYGFGHLVELYLPEQYDEKYKNWSINNLPIIPDQFKFKTGKGKAEQFKIVKNLLSEADQIIIATDADREGENIAWSIINQSGINPQEKIMKRLWINSLESSAIRDGLTNLHEAKQHYSAYIEAQTREFSDWLVGMNASPLYSLSLRKQGIRGVFSIGRVQTPTLYMIYKRQVEIDNFKPKPYIELLAHVKTGKSEFEAKLDPFIRFDNQDKVKVFLSDNELVLVNKSQSKENNNNFGIINNIIKDKKKQPSPKLFSLSTLQSRANKAFKASAQNTLDAVQSLYEKKFLTYPRTDTQFISDEEFSYLLDNINQYCEFANVTANIAHKEPRKRYVNSKKVQEHHAIIPTRTIPTKNQFMKLTSLEKSIYELVLRTTIAMFLDDLNYDEQVIIVKSGQAQFKAMGRVITTPGWKLLFKTNSKKSSANGEVSLPRVDIGQKVDFDLLDEHKVTVAPSAYTEGTLITAMKNAGRDLADAQKEILKETEGIGTEATRAGIIERLKAKSYIELKDNSLAVTMSGIILCQAVELQPLLNSPELTAQWEMALHEIGQNNRTQASFLKQIEKFILKLINEVPDQIETNQKLTDQINSQKDTNADQYKEHMGICPVCKAGHMIDRGKFYGCSNYNSKEACNFSLPSKWAGKILPKTAIKDLIKKGHTKEISGFKSKAGKSFSAILELVDGKLKFVFDK
(10) DNA topoisomerase [Roseburia hominis A2-183]
7
MAKSLIITEKPSVAQEFARILGVSGRNDGYIENDGYVITWCVGHLVEMVYPEEYDERYKKWRLEDLPFLPRDYKYNVIPSVSRQYDVVHKMLHREDIDTVYWAGDAGKEGQTIEENIRKFGGVREGMKELRVWIDSQTEEEILRGIREAKDMSEYDNLAKSGVMRTIEDYAMGINFSRAMSVKYGKLLNDAAGTSSYTAIAVGRVMTCVLGMVVIREREIRNFTETPFYRVVGTFHPEGEEECRITAEWKAIEGSKYFESPLLYKENGFKKEESAQTLIAELKGQEALIDSVETGTQKKRAPLLFNLAELQAECSKRFKISPDETLQVAQDLYEKKLTTYPRTDARVLSSAVAKEITKNISRLKNFAPVAPYVERIMKEGRCRNIANTQYTDDSKITDHYAIIPTGQLTELESLNSLERSVYEMIVRRFLSIFYPPAEYQTVKLVVAAGGEKLYTSAKQLKVPGYLEIAGIPKSAKERNAAKTDGEEQTQGGDAEAAQEEEENAGLLAYADKLQKGETLFSDGYVIREGKTSPPKRYTSGSMVLAMENAGQLIEEEELREQIKGSGIGTSATRAEIIKKLVRVGYLNLNKKTQVLTPERLGEMIFEVVSMTVPALLNPKMTASWEKGLDGITRGAVVMEDYRSKLEDFIRRETVAMIEQDLTGQIATRIHPLVGKGGKGLAAKRSLGIPCPVCGGTIETTPFGYGCSNYQKDGGGCRFSIGTIAGRDLNDEEVKELLTEGHTGVLSGFVSKSKKKFSASLILEKDDEGKVSVGFDFSKNQPEILEGVVCPVCGSAVEITPFGYSCVKHHEHPDECYFSVGKIAGKALGVDDLTELLTTGKTGLIRGFTARNKKKFNACLKLEQTEDGRKNIAFDFSQNDAAVVPDVVCPICGGAIVETSFGFGCANYRQDDPDSCRFAIGTMAGKDLNAAQVKELLNQGRTGTIRGFKSKSGKKFDACVALEHTEDGRIELRFDFEHVEAKKIKDVVCPICGGDIVATPFGFGCANYVKDDPNSCRFSVGKMAEKALTEANVKELLTNGRTGTIRGFKSKSGKKFDARVALAKDEKGKVTGLKFDFTDLEAPKVKDVKCPVCGGDIVKTMFGYGCANYSKENPDSCRFAIGKIAGVSLKEAQVKELLLRGKTDVIKGFVAKTGMKFDAPLKLTPEGQIAFDFPEKPKPVETTLACPKCGKMLKKSQWYYECECGFKVSHTVAKVALTEEVMRELLETGKTKDKVTGFVSKAGNTFDTCLKLEDDRIVFDFDNPGTKREGASDGKGGERMFYEELEENAQPQPLAAEDGAQYIEEDVPPFYDAMAEEYAAYEEEEAKQQAAASNFLDEFPG
(25) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(26) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(27) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(28) DNA topoisomerase [Peptoclostridium difficile 630]
7
MKLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLIQMANPESYDEKYAKWNMADLPIIPREYKYEIAKSTKKQFTILKKLMNDKEIDIVINACDAGREGEAIFRLVYNQANCKKKMKRLWISSMEDSAIKEGFDNLKDGSFYDNLFESAQARAIADWLVGMNLSRLYSCLYKQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYFTVELDLDGFSLSTDRIDDKTVTEQLINLLGNSIEITDVIQKEKITKPELPFDLTTLQRECNKYFNYSAKQTLDYTQSLYEKKLITYPRTDSRYLTEDMITSTINNIVGKHDFDTGRIKMVFNSKRVTDHHAIIPTASSMNEDLASLPESELKVYELVLNKLHASVGYPLIENTTKIVAVFDGFEFTSSGKVIVDEGFTKYLKKYIKKKNEDTVFPDLKIGDSLDIKEKEIKENYTSPAKHFTEDTLLKDMELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVSDTFKSAGTTAKWEMELSDIAQGKASKENFLKAIENEIKELVSTYSK
(29) DNA topoisomerase [Paenibacillus terrae HPL-003]
7
MKTLIIAEKPDMGRTIAAVMEPRAKNNRTYLEGEKYIVTWAIGHLLGLAEPDAYDAKYKRWNIKDLPIIPEQFKIVPNPKTKDQLKIIGELAKRCNAIVNACDAGREGQYIFALIQQQLKLRQPVKRLWISDLTAESIAAGFERLRDASEFEFLTQAARARSEADWLIGMNASRAFTTRHNALLSVGRVQTPVLALIHDREKEIEAFQSQTFYDVWAEFKQDQTKYKGAWQGDRLTKPEEAEAIAAAVRGKTGEITKYDTKQTKEYPFKLYDLTLLQREANAKYSYSAKKTLDVAQALYERHKVISYPRTNSNYVTEQNIDGMHKALRMLGTGPYADLVQQANPNLVHKQNKAVCNPSRVEDHHAILPTLKRPGTLSKEEQNVYDLIIRRFLSHFFPPAEYKMHTVMTQVDKHLFKTSIKELLSLGWKVVLSKADQDKGKKSKAPKKEEEEETDEWTDKKFEIDAGRLVDCIRAEMKEKATQPPKSYTEGTLLKAMESAGKQMENEELREVMKDAGLGTPATRAATIERLKKVGYIEMKGKKILITDKGKMAIDLIRNAGVDLLASPEMTGQWERRLHQISKGEAAQEKFMDNVKKFTLSIIDKVRQQPPAPANAFGEEARGKRSAGKENARSAGASVRTAAKGTRVPSGRGSSAGSATLERTAGAAGSAAGASPSRREALGSCPRSNCSGSIIEGRKGYGCSHYKQGCGFVVWKEYAGKQITETMLKSLLTKGQTQLLSFKRKDGSTVKARIVLNEPGTGQLSVREEN
(34) DNA topoisomerase [Ruminococcus bromii L2-63]
7
MKLVIAEKPSVGAAIAAVMGANEKRSGYFEGGGYLVSWCIGHLISLADAATYNEQFRKWKYDDLPIVPQEWQFIVASGKEQQFSILKDLMHRSDVTEIINACDSGREGELIFRFVYEQANCKKPFSRLWISSMEASAIREGFSNLKDGRGYDNLYQSALCRAKADWLIGINATRLFSILYHKTLNVGRVQTPTLAMLVNRDYAISSFKKEKYHVVRLDVGGVAALSERQDDEAAARQMKAACEKSQAVCTSLKKEKKTAAPPKLFDLTALQREANRLYGFTAKQTLDYAQALYEKRLLTYPRTDSKYITSDMEGSTKELITGLCAALPFMQGVKLQADLARICDNSKVTDHHAILPTAEFVKTGFSSLAESEKKLMTLVCAKLLCAVAAPYEYEAVTAVFTCGGYTFTAKGRTTLCEGWREIERLSRAASGEQDEDAEPEAVLPPLAEGQTFDNPAAEISERYTQPPKAFTEDTLLSAMESAGKEDTPEDAERKGLGTTATRAGIIEKLISAGFAERKGKKLIPTKDGYNLVAILPDSLTSPQLTAEWETRLTGIAKGSDSPADFMRGIEEMTAGLVKTYSAISEDKAKLFTPQREAIGTCPRCGAAVYEGKKNFYCSDRACSFVMWKNDRFFEQRKKAFTKAIAAALLKDGKVKIKGMYSTKTGKTFDGVVLLADTGGKYVNFRVEQNRK
(35) DNA topoisomerase III [Pedobacter saltans DSM 12145]
7
MKAIIAEKPSVAREIATLLGATEKRDGYLTGNGYEVTWALGHLVGLAMPEDYGVSGFQREALPILPNPFLLTVRKIKKDKSYVPDNGALKQLNIIEQVIGRCDSIIVATDAGREGELIFRYIYEYLKCRKPFERLWISSLTEKAIKQGFDNLKAGSDFDGLYRAGQGRSKADWLVGINASQALSISAGRGVYSLGRVQTPTLALICKRYLENKDFAVKKYFQIQLEHRKEFTDFKSLSKTKWDDRKLADDTLKSIQRNGTATVTAMETKTVTEQPPLLFDLTGLQKEANKRASYTAEETLNIAQSLYEKKFITYPRTGSKYIPEDMWSEIPALVRNLEARASCKKAVGKVKWGRFNKRIVNDVKVTDHHGLLITEKIPSELTAHENVIYDMIAYRLLEALSSACTKEITDIGLQAFHYDFTLKGCKIIEAGWRGIKGKFTDEDSDPVQELPELKVGDELKIKVASVLEKITKPPVLYTEAGLLSAMENAGKEIDNEDERKALKDIGIGTPATRASIIETLFKRDYIRREKKSLIPTHKGLQVYGAVKDKKIADVAMTAEWEMALQKIENNDANADAFHRDMETYATFITRELLDTGIAKEKQPELTCPKCKSRQLLVWNKVVKCPDEACGWLQFRIVCGVPLSVADIESLVTKGKTNLIKGMKSNSGNKFNAYIVMNDKAETSFEFENRKPKRK
(48) DNA topoisomerase [Desulfotomaculum acetoxidans DSM 771]
7
MKQLVLAEKPSVARDLSNVLGNFNKGNGYLESDAYIITWAIGHLVTLAEPDDYDAALKKWFLNTLPILPREFKLKPVSATLKQFNIVKSLLHRNDVGDIICATDSGREGELIFRYIYKLTDCQKPFKRLWLSETTPAAVRKGFDNLRPGNDLDRLAFAAEARSQADWLIGINATRAFTVKHNQLLSVGRVQTPTLALIVNREQEIRAFVPEKYWELFALFTKENGQTYIGKWFKKEKKAVENWEIPIQVGQKQTNQNPAASFEAAQGGIPSVMGEAVPSSNGQDKPVAMQTKFAAREAARDIQKKVTGQPGQVVSVEKKDIIEHPPLLFNLNDLQKEANKKFGLSAAKTLSVAQELYESRKLITYPRTDSRCITVEMGKTIPQRLGALAVVAEYENFIHLIKERKAFLNKRYINDSKVTDHTALIPTNVKPDLDKLSSDERRVYDLVVRRFLAAFFPPARYEQTQVITEVKQETFLSRGRVELDKGWKTVYDPVQDKLVDDEQGILPVIENEESVLTTKTDIKEKKTNPPKRYTEAALLSVMEGAGRLLNDEELKEAMRGSGLGTPATRAAIIERLLKVGYIERRKKTLLPTEKGENLIKLVPEQVKSPEMTARWEKALADIEDGQLNPGEFMSGIIEQTRQVVELARRQKTEGEPLRNNRDIIGKCPLCGRPVVEYPKSYSCSDYRAGCQFVIWKVILGKNITVEMARILLEKGRLEKQPGFISKNGKKFDAPLIIRNGRVEFDF
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Taxa distribution
Family tree
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