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Family 8
Informations
Name
8
# topoisomerases
130
Sub-families
No subfamilies.
Topoisomerases
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Name
Family
Sequence
(41) DNA topoisomerase 1 [Propionibacterium acnes 6609]
8
MSPTKSLVIVESPHKATMIAGYLGPKYTVRASQGHVRDLPTSASEVPAKYKGEPWARTGVNVDNEFTPVYVVSPEKRSTIRELKSLLKDSDELLLATDGDREGEAIAWHLLDELKPKVPVRRMVFNEITEKAINEAVAHTRKLDTDLVDAQETRRILDRLYGYEVSPVLWKKVLPRLSAGRVQSVATRLVVDRERERMAFTSANYWDMEATLTADLDEFQARLVSLDDTKIVTGRDFDSHGNLISSVRRLDEVAATAIAKALEKAPFTVTKVESKPYTRRPYAPFRTTTLQQEAGRKLGFTSQRTMSVAQNLYEGGYITYMRTDSVALSQEAIHAARNQAAELYGSDHIPDKPRIYASKVKNAQEAHEAIRPAGEHFRTPAETGLTGDEFRLYELVWMRTLASQMADAKGETLSVTIDATPVSPVNLPDGDVTTATFTASGRTITFHGFLRAYVESVDEGASDDAQKRLPQLSKGQDLDPREVTAKGHDTRPPARYTEPSLVAKLEELEIGRPSTYASIIRTITSRDYVFKKGSALVPTWLAFAVTRLLEEHFSNLVDYQFTADMEETLDQIARGNADRVAVLSAFYFGQTKTGDGDVPTPTEGHEGLHQLVTELGDIDARTICTFPLDDSDVVVRVGRYGTYVEDPEGNRANVDDALPPDELTVEAAKELLVSPNGQDRELGLDPHSHRPIVARNGRFGPYVTEVLDDDEATEIVETTTKDGKKRRTKRKVKPRTASLFRSMSLETVTLDEALKLLSLPRVVGTAADGTEITAQNGRYGPYLKKGTDSRSLGSEDEIFSITLEQAEAIYAQPKQRGRAAAKPPLRELGEDPASGRPIVVKDGRFGPYVTDGQTNATLRKDDSVEDITPERAQELLAEKRAKGPAKKSPTKKKTTRKTTTRTTTTKKTTKATSKSVKVTKANAKTSSGS
(43) DNA topoisomerase 1 [Gordonia polyisoprenivorans VH2]
8
MAETSTTSPTSGKAIRRLVIVESPTKARKIAGYLGSNYVVESSRGHIRDLPRGAADVPAKYKGQSWARLGVNVDENFEPLYVVSPDKKSTVTELKSLMRDVDELYLATDGDREGEAIAWHLLETLKPKIPVKRMVFHEITEPAIRAAAENPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVMPKLSAGRVQSVATRIIVERERERMAFVSAEYWDIDATMNAGGSQEDESNPRSFSARLVNVDDARVATGRDFTPKGVLKKADGVIVLDESRATALAGALDGADMTVTSVEEKPYTRRPYAPFMTSTLQQEAGRKLRFSSDRTMRIAQRLYENGFITYMRTDSTTLSESAINAARTQARELYGDNFVHPTPRQYTRKVKNAQEAHEAIRPAGETFRTPGQVAGQLETDEFRLYELIWQRTVASQMADAKGTTLSLRITGTATSGEECTFAASGRTITFPGFLSAYVETVDDQAGGQADDAENRLPQLTEGQSLTASELRADGHSTNPPARFTEASLVKVLEELGIGRPSTYASIIGTIQDRGYVVKKGNALVPSWIAFAVVGLLEAYFESLVDYDFTASLEDDLDQIANGQENRTRWLTEFYFGDSAANAEHDAEIAGSEIAKHGGLKKLVGVNLEEIDAREVNSIRLFDDEQGRPVYVRVGRFGPYLERNVAASADAEPDLQRANLPADMTPDELTLAVAEKLFSTPQEGRTLGTDPVTGHEIVVKEGRFGPYVTEILPAEEDGDDSGSAGAPATIPAGPTPRDGGGAGDGEVVPLDDTPADTGGSTSGGSTATKTAAKKAVAKKAAAKKTAKKAAGPKPRTGSLFKTMDISTVTLDDALKLLSLPRVVGVDPASNEEITAQNGRYGPYLKKGTDSRSLTSEDQLFSITLDEALKIYSEPKRRGRAAAAPPLRELGKNDEVSGQPMVIKDGRFGPYVTDGETNASLRKGDEVASITPERAMELLADRRARGPAKKATKKAAKKTPAKKTAAKKTTAKKTAAKKTTAKKTTAWKTAAKKTAPDATED
(44) DNA topoisomerase 1 [Arthrobacter sp. FB24]
8
MPSKAKTGKKLVIVESPAKSKTIAKYLGEGFIVEASIGHIRDLPQPSELPAELKKTSIGKFAVDIEHDFKPYYVVSPDKKKKVTELKAALKDADALYLATDGDREGEAIAWHLLEVLKPKVPVYRMTFGEITKEAIQRAMGNLRDVDQDLVDAQETRRVLDRLYGYEISPVLWRKVARGLSAGRVQSVVTRMVVDRERERMAFKAASYWDLTGQFGAGNGATSSFKAKLAAVDGAKVASGRDFNDDGELTSRNVTHLNEELATSLAAGLQNAEFRVRSVDTKPYTRRPAAPFTTSTLQQEAGRKLRFSSKSTMQVAQRLYENGYITYMRTDSSALSDEAVTAARRQASELYGPEYIPQSPRVYTGKAANAQEAHEAIRPAGDSFRTPAQVAKQLSGDEFRLYELIWKRTVASQMGDAKGSTATIRLGAVAADGRDAEFSASGTVITFPGFLAAYEEGKDESRGDDDSEEARRLPNVAKDDALTASEIVAVGHETSPPPRYTEASLTAELEKKGIGRPSTYASTISTIQDRGYVRKQGSALVPSWIAFSVIRLLEQHFHDYVDYEFTADMEGDLDKIANGQAVGAAWLKHFYYGEDSDPGLLSIVNNLGEIDAREINSVPIAEGITLRVGKFGPYLESSVPTIDPKTGEVVESARANVPEDLAPDELTAAKAKELMETAAPEERVLGEDPHTGHTIVAKNGRYGAYVTEIIPEMTDEQLANQPVEYYKNGKPKPPKKPVKAKPRTGSLFASMSVDSVSLDEALQLMSLPRALGQDAEGNVITVQNGRFGPYLKKGTDSRSIGSEEEIFTITLEQALEIYSQPKQRGARAAVPPLAEFGPDPVSEKNIVVKEGRFGPYITDGITNITVPRSTSLEELTREQAVELLAEKRAKGPAKRPAARKAPAKKKAVAKK
(106) DNA topoisomerase 1 [Mycobacterium tuberculosis H37Rv]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(107) DNA topoisomerase 1 [Mycobacterium tuberculosis H37Rv]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(114) DNA topoisomerase 1 [Streptomyces scabiei 87.22]
8
MSPTSETAKGGRRLVIVESPAKAKTIKGYLGPGYIVEASVGHIRDLPNGAAEVPEQYTGEVRRLGVDVEHDFAPVYVVNADKKAQVRKLKDLLKESDELFLATDEDREGEAIAWHLQEVLKPKVPVKRMVFHEITKAAIQAAVANPRELNQRLVDAQETRRILDRLYGYEVSPVLWKKVMPRLSAGRVQSVATRLVVERERERIAFRSAEYWDLTGTFATGRAGDASDPASLVARLQSVDGRRVAQGRDFDSVGQLKGANVLHLDEANARALAAALENTRFSVRSVESKPYRRSPYAPFRTTTLQQEASRKLGFGAKATMQVAQKLYENGFITYMRTDSTTLSETAVAAARAQVTQLYGADYLPAQPRTYAGKVKNAQEAHEAIRPSGDRFRTPAETGLTGDQFKLYELIWKRTVASQMKDATGNSVTVKIGGTASDGRDAEFSASGKTITFHGFLKAYVEGADDPNAELDDRERRLPQVGEGDALSAEQITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGYVFKKGTALVPSFLSFAVVNLLEKHFGRLVDYDFTAKMEDDLDRIARGEAQAVPWLKRFYFGEGTGSGGTAAEAGNGDGDHLGGLKELVTDLGAIDAREVSSFPVGDGIVLRVGRYGPYIERGEKDAEGHQRADVPEDMAPDELSVELAEELLAKPSGDFELGADPATGHQIIARDGRYGPYVTEVLPEGTPKTGKNAVKPRTASLFKSMSLDTVTLADALKLMSLPRVVGADAEGQEITAQNGRYGPYLKKGTDSRSLQTEDQLFTITLEEALAIYAQPKQRGRAAAKPPLKELGEDPVSAKPVVVKDGRFGPYVTDGETNATLRSGDSVEEITPERGYELLAEKRAKGPAKKTAKKAPAKKTATKTAAKKAAPAKKTAAAKTAASKTAAAKKAAPAKKAAAKKATSAGESA
(125) DNA topoisomerase 1 [Rhodopirellula baltica SH 1]
8
MSDKPESRTSETPIFPPRIGSFLLMAKSTSKSLVIVESPAKARTISKFLGSGYQVEASVGHVRDLPGGAKDIPKKFKKEPWAYLGVNVEKDFEPVYIVPADKKKQVDKLKAALKDADSLYLATDEDREGEAISWHLFELLKPKVPVHRLVFHEITKEAIQHALEDPREIDDGLVRAQETRRILDRLYGYDVSQLLWKKVGRGLSAGRVQSVAVRLIVQRERERIAFHDATYWDLEAIFTTDNGDSLPAMLATVDGRKIPTGKDFDSTNGQLINPELLQMDEQQAKELKQKLEKENFRVAKVEVKPFTERPKAPFTTSTLQQEANRKLGFTARRCMQAAQRLYENGYITYMRTDSTTLSKEAINAARDLVRSEYGEKFLHDSVRVYKGKVKNAQEAHEAIRPAGTPFRVPGAVQNELDRDQFRLFELIWKRTVACQMADAKKQRISVTIEGGGTTFTASGTSILFEGFLRAYVEGSDDPEAELADKERLLPAVNENDGLSVATLDPKSHTTQPPSRFSEASLTRTLEEKGIGRPSTYASIIDTIQRRDYVYKKGNALVPSWTAFSVIRLMETHFEPLVDYDFTAQMEDFLDTISRQEAESLQYLKRFYFGDETEPTGDEKAAIGLKPRLESKIEEIDPRVTAKFSLGIPTEGENREEVFVRVGKYGPFLEQGERKAPILEGMAPDEMTLARAMELFEDAAREDEPLGVHPETGKPIYIKAGRFGPYVQMGEKDDEEKKNASILKTIAVEDVDLEMACKLLSLPRDLGEHPEMKEPILAHDGRYGPYVKCGKETRSLPADKSPLDVTFDEAIELLKQPKTRGRAAPKEPIKKFEKPSPVTENEIKILEGRFGPYATDGETNASIPRGTDPKEMTFESVLDLLAERAAKGPTKKKKKKKAVKKKTAKKAAKKKTAKKKAAKKKTAKAAAKKKGIIKKSS
(152) DNA topoisomerase 1 [Gardnerella vaginalis HMP9231]
8
MTEQNKLVIVESPTKARKIGGYLGSGYTVMASVGHIRDLAQPSQVPAAKKAEFGKFGVDVNNGFEPYYVVGADKKKTVSDLKAALAKSGELFLATDEDREGEAIAWHLVQALKPKVPVKRMVFHEITKDAIQASLANTRNVDDHMVDAQETRRVLDRLYGYELSPVLWRKVGPGLSAGRVQSVATRLIVERERERMAFKKASYWDVCADLSANGVDFQARMTALNGERLAASKDFNSLGELQKTKGESALAHYLNEADACAIAQSLGAADFVVSSMDTKPYRRRPLPPFTTSTLQQTAGNRLSMSSRQTMRAAQSLYENGYITYMRTDSVTLSKEAIFAARDCVKSSFGDEYLADSPKQYATTSAGAQEAHECIRPAGSTFRNPADLAGVLPADQLKLYTLIWQRTLASQMADATGFTATVKLDASAGSFGTANFQASGTVIEFAGFMKVFGGFSEDEQSKALPPMANGDVLKALRVSADGHETQPPARYTEASLVKTLEAKEIGRPSTYASIISTIIDRGYVYERGRALIPSWLAFAVIKLLESNFPTYVDYAFTADMENGLDRIAHGEEAGKDWLYKFYFGDNGAVAGDFAMHEGLQKQVDQLGEIDAREINTIDIGGGLHVRVGRYGPYLEDTKNLDEEGNARRASIPSTLAPDELTEQVARDLIENNSDGPRVLGTDPQTGGSVEVRNGRFGAYVALVEASDEDESQASDDSAKTGAKSSAKSKKSAKAKPKMASLFKTMDPATITLQDALRLLNLPRLVGIVEEVDEQGEVKRAKIEANNGRYGPYLTKTYERADAGDSAAAVDAKPDNRSLASEDAIFSVTLDEAKELFAQPKYAKRTRGAAKPPLRELGEDPESGKAVVIKDGFYGAYITDGVTNRTLPKQYTPESIEPQVAFELLAQKRAAGPVKRKRTAAKKTATKKTAAKKTAAKKPAAKKSTAKKSTSKVE
(158) DNA topoisomerase 1 [Bifidobacterium breve UCC2003]
8
MATKLVIVESPTKAHKIGDYLGKGYTVMASVGHIRDLAQPSQVPAADKPKFGKFGVDVNDGFKPYYIVDGDKKRTVSELKSALKGADELYLATDEDREGEAIAWHLVQTLKPKVPVKRMVFHEITKDAINASLSKTRDVDSHMVDAQETRRILDRLYGYELSPVLWRKVGPGLSAGRVQSVATRLIVERERERMAFKRAPYWDVVATLAASDALGERTEFAARMISLGGKRLAGSKDFGSDGQLTPDGFAGSVRQLDEASATAVAEALKNADFTVMSMETKPYRRRPQPPFTTSTLQQTAGNRLGMGSRAVMRAAQSLYENGYITYMRTDSVTLSQEAITAARNAVSYHFGDKFLSAEPKQYATKTAGAQEAHECIRPAGSRFHDPDELASKLPIDQLRLYTLIWQRTLACQMADATGSTATVRLSAPAGPADGEAVFQASGTVIEFPGFMKATGEGRKPKPAAADAAAADKSGAKATKSDASESNASLPPMEVGQRVEASDIEPDGHETQPPARYTEATLVKTLEAKEIGRPSTYASIISTIMDRGYVYERGRALIPSWLAFSVTKLLETNFPKLVDYTFTAEMENGLDRIAHGEETGRDWLTHFYFGSGEGAARNADEAHEGLQQQVAQLGEIDARAINTIDIGDGLHVRVGRYGPYLEDMEHLDAEGNPKRASLPDTIAPDELTVEVAHDLTDNHSGGPRELGKDPVSGGTVEVRNGRFGPYVALVPPEGAADSAATAPAGKKSSKKAAAAASRPRMASLFKTMSPESLSLEDALKLLSLPREVGKYEETNAETGEVSECTVAANNGRYGPYLTKTSADGRSDTRSLGSEDEIFTVDIDKAKELFAQPKYGRGRGRGAAKPPLRDLGNDPNTGKHVTIKDGRFGAYITDGETNRTVPRQYTPESIAPEDAFRLLAEKRAAGPSTRGRRGRERAGAAKSGARGAKKGAASAATNAAEAKRAGRRAEVKKLANKGWSNQRIAEKLSSTAATVKKDVDWLTANEGYERPAVIPKRG
(168) DNA topoisomerase 1 [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1]
8
MATTPRRLVIVESPTKATKIAGYLGPGYVVESSRGHVRDLPTSAAEVPAKYKGQSWARTGVNVDDDFAPIYVVSADKKSTIKQLKAELKNADELYLATDGDREGEAIAWHLLQELKPKIPVKRMVFHEITPAAIQEAVKHPRTLDEDLVEAQETRRILDRLYGYEVSPVLWKKVMPRLSAGRVQSVATRLIVDRERDRMAFRAASYWDIEAILDAGASATPRQFPARLVSLDGQRIAQGSSFDSLGHAKSDVAVLDKPATDALSSALATAPFVVTAVEAKPYTRRPAAPFRTTTLQQEAGRKLGFTTDRTMRVAQELYEDGYITYMRTDSVTLSGQAITAARDAITQLYGADYVPERPRIYNSKVKNAQEAHEAIRPSGEHFRTPAQTGLRGDQFKLYELVWQRTVASQMADATGQQMTVRIEATPTQRVALEGVTPQPVRTAQFTASGRTITFQGFLKAYVESSDKPEQAQARLPQLAAEQKLDAAAINPEGHETKPPARFTEPSLVAKLEELDIGRPSTYASIIRTITSRDYVFKRGSALVPTWLAFAVTRLLEEHFSELVDYDFTAALEDHLDEIAKGDADRLAVLQSFYFGNNNADTHEGLHELTNSLGDIDARALSTFHLGDLGSGIDVRVGRYGTYVQDEEEHRANVPEDMAPDELTVEAARELLAHTGGDERELGLDPTTHLAIVVKAGRFGPYVTEVLPDDDDAPAAKKSKVKPRTASLFRTMDPATVTLDDALKLLSLPRVVGGEGEEQVTAQNGRYGPYLKKGSDTRSLPSEESIFTTTMEQAAELFAQPKRRGRQAAAPLRELGEDPNSGKPVVVKDGRFGPYVTDGEYNATLRKADSVEAITLDRAAELLAEKRAKGPAPKKRTTRKATAKKAAAAKKPAAKKPAAKKPAAKKTASTAKPAAKKPAAKKSASTSTN
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Taxa distribution
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