Toggle navigation
TopoIBase
Data
Taxonomy and VLD families
Downloads
My selection
Upload to selection
Selection 1
Selection 2
Selection 3
Tools
Blast
MUSCLE
VLD
About
How to use
Acknowledgements and references
Contact
Tests
Search more
Download
fasta
tsv
Download
Blast
Muscle
VLD
Add to selection
Selection 1
Selection 2
Selection 3
All selections
Family 9
Informations
Name
9
# topoisomerases
147
Sub-families
No subfamilies.
Topoisomerases
Select all
Name
Family
Sequence
(33) DNA topoisomerase 1 [Hahella chejuensis KCTC 2396]
9
MTAISTRSKEPSAMGKSLVIVESPAKAKTINKYLGSEYVVKSSVGHIRDLPTSGGKETSSPKERAAEAAKMRKLPAEERESIKKRKARDQLISRMGVDPENDWAARYEVLPGKEKVVEELRRLAKSADQIYLATDLDREGEAIAWHLKESIGGDDSRYRRVVFNEITKSAITEAFKSPGQLDYNRVNAQQARRFLDRVVGYMVSPLLWSKIARGLSAGRVQSVAVRLIVEREREIRAFTPEEYWELHALLSKSKQQAKFQVAKYKGENYRPTNKAQSDKLTALLQTQAFKVVNREDKPSVTKAPAPFITSTLQQAASTRLGFSVKKTMVLAQRLYEAGYITYMRTDSTNLSADAVNACREFIGKKFGDKYLPDNPKTYVSKERAQEAHEAIRPSDINVGANQISGLEKDAEKLYDLIWRQFVACQMENARFLSTSIQVQAGDFELRTRGRLLQFDGFLKVLPAQAKKDDEAELPAFEVNDQLDLDKLEPTQHFTKPAPRYTEATLVKELEKRSIGRPSTYASIISTIQERGYVKLANRRFYAEKMGDIVTDRLTEAFTDLMDYGFTAKMEGQLDEIASGNEGWKQVLNAFYSDFAKKLEKADMEGGMRANQAVQTEIACPTCSRPMQIRTASTGVFLGCSGYALPPKERCKTTINLIPGDEVIRADDEEGEANALRAKKRCPICDTAMDSYVIDETRKLHVCGNNPDCEGYEVEGGQFKVAGYDGPTLECDKCGAEMQLKTGRFGKYFGCTSSTCGNTRKLLKNGEPAPPKMEPVVMPELACDKVDDIFVLRDGASGLFLAASKFPKNRETRAPLVEELIPHKKEIDPKHHYLLEAPTRDPEGNPAIIRFSRKTKQQYVMSEKGGKPTGWSAFYKDGKWVAKDK
(58) DNA topoisomerase 1 [Shewanella denitrificans OS217]
9
METIFYLFETFGANKTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSTSDGSASTKTAAEVRKMSPEEKAKYKLIRDKQALVSRMGINPEKGWAAKYQILPGKEKVVKELKALAESADQIYLATDLDREGEAIAWHLQEIIGGDASRYQRVVFNEITKSAIQDAFSQPSSLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDINAELNTAASQVLKMQVAKYQGESFNPINKAQAEQAVERLTNASYSVSAREDKATSSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEAVENVREMIAADFGTKYLPADPIRYGSKEGAQEAHEAIRPSNVQVQSASLTDMERDAQRLYELIWRQFVACQMTPAQYDATRLTVKAGDYELKASGRTLRFDGWTRAQPPMGKKNEEDNTLPHVDKGESLTLNTLAPKQHFTKPPARYGEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFFAEKMGEIVSDRLVGSFKELMSYDFTASMEQTLDDVAQGKLEWKQVLDGFYGDFTKQLEKAELDPEDGGMHLNQMVLTEAISCPTCDRPMGIRTGTTGVFLGCSGYALPPKERCKTTMNLTPGEEAVSDAEDAETDALRAKHRCGKCGTAMDSYLIDEKRKLHVCGNNPSCDGYEVEAGQFKIKGYEGPLIECDRCGNDMELKNGRFGKYFGCTNSECKNTRKLLRSGEAAPPKEDPIFLPELKCTKSDAHFVLRDGAAGIFMAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPVEDDDGNKAAVKFSRKTKEQYVATEVDGKATGWTAKYHGGKWLVEQTKKKAKS
(60) DNA topoisomerase 1 [Klebsiella oxytoca KCTC 1686]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERGALVNRMGVDPWHDWNAHYEILPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVTHNGDKPFRPVNRDETMAAVALLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYIGDNFGKKYLPESANQYASKENSQEAHEAIRPSDVNVLAETLKDMESDAQKLYQLIWRQFVACQMTPAQYDSTTLTVKAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPMVNKGDSLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKQVLDSFFGDFTSQLQTAEKDPEEGGMQPNPMVLTTIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLAEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVASEKDGKATGWSAFYIDGKWTEAKK
(64) DNA topoisomerase 1 [Baumannia cicadellinicola str. Hc (Homalodisca coagulata)]
9
MNKALVIVESPAKAKTINKYLGNQYLVKSSIGHIRDLPIHRETVKQQGKTNYQNTLANRMGIDPYNNWFANYEILPGKEKLVNELKALANKAKHIYLATDLDREGEAIAWHIREVIGGDNSKFSRVVFNEITCNAITQAFQSPRELNLHRINAQQTRRFMDRIVGYMISPLLWKKIARGLSAGRVQSVAVKLIVEREREIKQFSPIEYWDLYSYLQGPKDIVLKMQVTHLNNKPFKPINSLQVQSAIALLNNARYIVCCREDKITSSNPNAPFITSTLQQAASTRLGYSVKQTMLVAQRLYEAGYITYMRTDSTKISDEAINIVRNYILDIFGSKYLPNQPNQYLSKKNSLEAHEAIRPSNLHILAEQLENIEEDARKLYQLIWRQFVSSQMMPTQYNYTKINVIAGDFQLSTTGRTLHFDGWSKVMPILHKENEESICQSISVGQILSLQQLISQQNFTKPPLRYTEASLVKELEKRRIGRPSTYMSIIDSIQDRGYVKLNNHRFYAKKIGQIVTDRLAENFSELMNYDFTANMEDTLDKVATNQQDWKNVLDTFFIKLNQQLEKAKKSPTEGGMLPNSIVTTSINCPICGRMMGICTANTGVFLSCSGYKLPPKERCKHTINLISESEWLKKLDNENKSIDTQKVRSRCIKCNNIMDSYYFNNNSMLNICNNNPLCDGYEIEQGLCLLNTDYGTLVPCEKCSANMQLRIGRFGKYIACTNNTCKNTRNILRNGDIAPPKMELIEFPELPCKNSNAYFVLRNGAAGVFLAANTFPKVHETRAPLVEELVKFKDRLPTMLRYLTEAPIQDDQGNKTLVRFSRKKKQQYISSEKEGKATSWKAFFINGHWQVYNKEDQ
(71) DNA topoisomerase 1 [Alcanivorax borkumensis SK2]
9
MGKSLVIVESPAKAKTINRYLGDDFIVKSSVGHVRDLPVSGGSKKSTPQERAKEAAYTRSLPKEERDAYKKKKAKKQLINRMGIDPENGWAAHYEVLPGKDKVVDELKRLAAKADRIYLATDLDREGEAIAWHLREVIGGDEERFDRVVFNEITKKAIQAAFEEPGKLDLHRVEAQQARRFLDRVVGFMISPLLWEKIARGLSAGRVQSVAVELVVEREREIRAFIPEEFWELYSDTHSGDGEALRLQVAKHNGLAFRPNNGDDAAAHKQALENAGRLTISQREQRPTRSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSSDAVAACREWIGEKLGDKYLPDEPLSYSSKEGAQEAHEAIRPSDVRRTSDSLKDMERDAQRLYELIRRQFIACQMPPAEYLSSTLTAIGNGYELKAKGRIMKFDGWTRIQPPASRKGQEDTLLPDVKEGDVLAIDNVDANQHFTKPPARFTEASLVKELEKRGIGRPSTYAAIISTIQDRGYVRQDNRRFYAEKMGDIVTDRLVESFPNLMDYGFTASMEETLDEVAEGRRNWQDVLNEFYKDFVSKLDAAQGEGTGKQAVGGMRANLPTDTDIECPSCGRPMQIRTGSTGVFLGCSGYALPPKERCTATLNLLPGEEAEAVKTDDDEEAETNELRSKKRCQKCGTAMENYLIDEKRKLHICGNNPDCDGYVIEKGEFRIKGYDGPVLECEKCGNDMQLRTGRFGKFFKCTNDECGNTRKLLKSGEPAPPRADPIPMPHLQCQKVDDHYLLRDGASGLFLAASKFPKNRETRPPLIEEIQSVAEQLDPKHAYLAQAPATDPDGNKGVLRYSRKAKEQYVMSEIDGKATGWMAFYRDGKWVEEQAKKKAPAKKKAAAKKKATKKKAAAKK
(79) DNA topoisomerase 1 [Erwinia tasmaniensis]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPISGSTVKKSTDSTTSKTTKKVKKDAKTALVSRMGVDPFHHWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIHQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWDLNADLTTPKGIDLPMQVTHQHDKPFRPVNRDQTYAAVSVLENARFTVVDREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYVEDEFGAKYLPKTANIYSSKENSQEAHEAIRPSDVKIQSEQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDERTLPAVEVGSELSLQQLLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKTVLDKFFGEFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCDKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEDCKNTRKILRNGDVAPPKEDPVPLPELVCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAEDADGNKSVVRFSRKTKQQYVSTEKDGKATGWSAFFVDGKWEVAAKK
(87) DNA topoisomerase 1 [Mannheimia succiniciproducens MBEL55E]
9
MSKSLVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTAGASTGEKAKPVSTKGLTAEEKQALKTEKEKNALVKRMGIDPYHGWKANYQILPGKEKVVADLKSLAKKADHIYLATDLDREGEAIAWHLREVIGGDDNRFSRVVFNEITKNAIKQAFEKPEHLNLDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLVVEREREIKAFQPQEYWEVAVVTKTADNQKITLDVAEYKGKRFDPKNETEAQSAVDFLAKSDYIVSALETKPTTSRPRAPFITSTLQQTASTRLNFSVKKTMMLAQRLYEAGYITYMRTDSTNLSRDALNMARSYIERNFGEKYLPEKPNFYSSKENAQEAHEAIRPSDVNISMNDLQGMEKDAVRLYDLIWRQFVACQMPAAQYDSTTLTVKAGDYELKAKGRILRFDGWTKVLPQLGKSAEDQELPALNVHNKLALDEIQPSQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNQSFAHLMSYDFTASMEDMLDQIATGKKDWKTELNQFFKDFSGQLTTAELDELEGGMKPNSLVLTDIQCPTCGRPMAIRTASTGVFLGCSGYALAPKDRCKTTINLIPEAELLNVLDDASETKALMERKRCPKCDTAMDSYIIDPHRKIHICGNNPNCEGYLIEQGTFKIKGYDGPIVECDKCGSDMHLKLGRFGKYMACTACDNTRRILANGEVAPPKEEPIAFPELKCEKADAYFVLRNSAVGVFMSAHNFPRVRESRPAKVAELAQYRERLPEKLQYLADAPQQDPEGNPAIISFSRKEKHQYVTSEKNGKKTKWIVDYIDGNWIERKK
(93) DNA topoisomerase 1 [Serratia proteamaculans 568]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDPTTALVNRMGVDPYHGWKAHYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKGDTALQMEVTHAHDKPFKPVNREQTHAALNVLEKARYTVLDREDKPTSSKPGAPYITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALEMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAADYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMENGLDQVANNQAEWKAVLDEFFAEFSEQLETAEKEPEEGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNESCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADAEGNKTLVRFSRKTKQQYVSAEKDGKATGWSAFYIDGKWVEGKK
(96) DNA topoisomerase 1 [Aggregatibacter aphrophilus NJ8700]
9
MSKSLVIVESPAKAKTINKYLGSNYVVKSSVGHIRDLPTIGSANGEKAKPISTKGLSLEEKQALKQKKEQDALVKRMGIDPYHGWKANYQILPGKEKVVAELKSLAKKADHIYIATDLDREGEAIAWHLREVIGGDNERFSRVVFNEITKNAIKQAFEHPESLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLIVEREREIKAFVPQEYWEVSVLTDTAKHEQIRLDVVQFKGKKFEPKNAEQAQSAVDFLTKSDYVISDLETKPTSSKARAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMVRGYIEKHYGAPYLPAKPNFYSSKENAQEAHEAIRPSDIHIGSHDLVGMEKDAERLYDLIWRQFVACQMPAAQYDSTTLTVRAGDYTLTAKGRILRFDGWTKVLPQPGKSPEDQALPDVAVNTTLNLLTVEPQQYFTKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNQSFADLMNYDFTANMEDVLDQIASGTKDWKTELNQFFKDFSKQLSKAELDELEGGMRPNSLVPTDIHCPTCSRNMAIRTASTGVFLGCTGYSLPPKERCKTTINLIPEAELLNVLDDASETKALMERKRCPKCSTAMDSYIIDPHRKLHICGNNPNCDGYLIEEGKFKIKGYDGPIVECDKCGGDMHLKLGRFGKYMACTQCDNTRKILKNGEVAPPKEEPIHFPELRCEKSDAYFVLRDGAGGVFMSAHNFPKSRETRAPKVAELALYRDRLPEKLSYLAEAPQTDPEGNEAIIRFSRKEKRQYVTSEKNGKATKWIVDFVDGKWVERKK
(108) DNA topoisomerase 1 [Pseudomonas entomophila L48]
9
MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSASASKEPAAKRGKTAGEAPALSPKEKARRQLVARMGVDPEAGWKAKYEILPGKEKVIDELRRLAKDADTIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIQEAFSQPGDLDIDRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFNPEEYWEVHADLGTAKNAKVRFEVAREKGEAFKPLNEAQAMAALEKLKASSYSVVKREDRPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSTDAVEMARSYIENEFGKQYLPDAPVVYGSKEGAQEAHEAIRPSDVNTHPTKLSGMERDAERLYELIWRQFLACQMPPAQYLSTSVTVAAGDFELRAKGRILKFDGYTRVLPQQSKPGEDDVLPEMAQGEALKLIQLDPSQHFTKPPARFTEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVTLHNRRFYSEKMGDIVTERLSESFANLMDYGFTAGMEENLDDVAQGERDWKNVLDEFYGDFSKKLLTAESAENGMRANQPTLTNIACKECGRPMMIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEGESESLVLRGKHRCPICATAMDAYLLDEKRKLHICGNNPDCAGYEIEEGSYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNATCKNTRKLLKSGEAAPPKMDKVDMPELKCEKVDDTYVLRDGASGLFLAASQFPKNRETRAPLVLEIVPHKHEIDPKYHFLCDAPQKDPDGRPAVIRYSRKTKEQYVQSEVDGKPTGWKAFFDGKAWKVEDKR
(130) DNA topoisomerase 1 [Pantoea ananatis PA13]
9
MGKALVIVESPAKAKTINKYLGSGYVVKSSVGHIRDLPTSGSTAKKSAETSTDKKVKKVKKDEKAALVSRMGVDPYHGWEADYQILPNKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIRQAFDTPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELSANLTTPKGDDLAMDVTHAGDKPFRPVNHEQTHAALALLEKARFAVTDREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYIEGNFGKKYLPDNANTFASKENSQEAHEAIRPSDVDVVAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVTAGDYKLKAKGRTLRFDGWTKVMPALRKNDEDRTLPPVNVGDELSLQALLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMESSLDQVANNQAEWKAVLDRFFSDFSQQLEQAEKDPEEGGMQPNQMVLTTIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNGRKLHVCGNNPECDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFHDRLPEKLKYLAEAPATDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFYIDGKWQEAKK
(135) DNA topoisomerase 1 [Marinobacter aquaeolei VT8]
9
MGKSLVIVESPAKAKTINKYLGSDFIVKSSVGHIRDLPVSGSGSQSDPKERAKQAAATRKMSPDEKAEHKKRKAREQLVARMGVDPDHDWSARYEILPGKEKVVSELKRLAKSADHIYLATDLDREGEAIAWHLQETIGGEPDKYRRVVFNEITKRAIQEAFKDPGNLDNNRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVRLIVEREREIRKFVPEEFWQLHADLAAEGAKDPVRFEVTRYIDKPYRPVNEAQSKEHVERLKAGGFKVAKREDKPTRSRPSAPFITSTLQQAASNRMGFSVKKTMMLAQRLYEAGFITYMRTDSTNLSQDAVVSCREFVQKQFGERYLPEKPRVYGSKEGAQEAHEAIRPTDVARRPTDITGLEKDAEKLYDLIWRQFIACQMADAEFLSTSIVVANGDYELRTRGRIVKFDGFLKAAPQSTKKDEDVALPDIKVDQPLDLKKLDPTQHFTKPAPRYTEASLVKELEKQGIGRPSTYASIISTIQDRGYVKLQNRRFYAEKMGEIVTERLAESFPNLMDYDFTARLEDELDEIAEGEVQWKKVLNDFYAKFRNQLESAEKTDGGMRANTPTETDIPCPSCGRNMQIRVASTGVFLGCSGYSLPPKERCKTTINLVSGDEVVSADDDVEGEGETRLLRKKRRCPKCGTAMDSYLIDEKRKLHVCGNNPDCSGYEVEEGTFRIKGYDGPTLECDKCGSEMQLKTGRFGKYFGCTNSECKNTRKLLKNGEPAPPKMDPVPMPELKCDKVDDTYVLRDGASGLFLAASKFPKNRETRPPLVMEIKPHRKEIDPKYDYLMDAPEKDPEGNPTVIRYSRKSKEQYVMSEKDGKATGWSAWFENGRWVPRDKKK
(159) DNA topoisomerase 1 [Pseudomonas brassicacearum subsp. brassicacearum NFM421]
9
MGKSLVIVESPAKAKTINKYLGDQYVVKSSIGHIRDLPTSGSASASKEPAAKRGKAAAGEAPALSPKDKARKQLVSRMGVDPEHGWKAKYEILPGKEKVIEELRRLAKDADTIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIQEAFSQPGELDIDRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWEVHADLGTAKGATVRFDVAREKGEAFKPLNEAQAMAALEKLKASSYSIVKREDKPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSVDAVAMARTYIESEFGKKYLPDTPNVYSSKEGAQEAHEAIRPSDANTEPSKLSGMERDAERLYELIWRQFLACQMLPAQYLSTTVSVGAGDFELRAKGRILKFDGYTRVMPQITKPGDDDVLPDMAQGDVMKLIKLDPTQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVALHNRRFYSEKMGDIVTERLSESFSNLMDYGFTAGMEENLDDVAQGERDWKNVLDEFYGDFKKKLEVAESPDSGMRANQPVMTDIPCLTCGRPMQIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEGESESLVLRGKHRCPICSTAMDAYLLDEKRKLHICGNNPDCAGYEIEEGTYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPTCKNTRKLLKSGDAAPPKMDPVKMPELKCEKVNDTYILRDGASGLFLAASQFPKNRETRAPLVMEIVPHKDEIDPKYHFLCEAPQKDPEGRPAVIRYSRKTKEQYVQTEVDGKPTGWKAFYDGGKWTVQDKS
(160) DNA topoisomerase 1 [Acinetobacter sp. ADP1]
9
MANAPRSTTKKSTTASSEPAGNKRALVIVESPAKAKTINKYLGSQYIVKSSVGHVRDLPTGGSAKSGEKKPATRAKLTAEEKEQKAQNALINRMGVDPEHDWKAHYEVLPGKEHVVAELKKLASQVDEVYLATDLDREGEAIAWHLKEVIGGDDSRYQRVVFNEITKNAIQEAFKHPARLDTNKVNAQQARRFLDRVVGFMISPLLWEKIARGLSAGRVQSVAVKLVVERERDIRAFIPEEYWQIFADTLSKKDQIRLEAVKQAGKTLKLRNKADTDAVLNLLKDAEYKVAQREDKPTKVNPSAPYITSTLQQAASTRLGFSVKKTMMLAQRLYEGGFITYMRTDSTFLSDDAVNMVRDHIQQQFGDKYVPAKPNRYGNKAGAQEAHEAIRPSNVALTGDQLAGMERDAQRLYDLIWRQFVACQMTPAEYLSSTLIVDANNVELRAKGRTLVFDGFTRVRGANKSDDDVLLPAVKVGETLKLEKLDPSQHFTKPPARFTEASLVKELEKRGIGRPSTYAAIISTIQDRGYVKLENRRLFAEKMGEIVTDRLDESFNNLMNYAFTADLEGQLDKVATGERNWKELLDSFYGDFKNRLNMAASTEGMRRNQPVEVPDVACQLCSRPMQIRTGTTGVFLGCSGYNLPPKERCKGTLNLTPVESLAAFSDDDSAETADLMAKHRCAKCGTAMDSYVIDGGRKLHVCGNNPDCDGYEVEEGEFKIKGYDGPTIPCDKCDGEMQLKTGRFGPYFACTSCDNTRKVLKSGQPAPPRVDPIKMEHLRSVKHDDYFVLRDGAAGLFLAASKFPKIRETRAPKVAELRTVAEQLDPKYQYLLQAPDADPEGNPALIKFSRKNQAQYVGSETPEGKQTKWSLVYQDGKWTEA
(186) DNA topoisomerase 1 [Tolumonas auensis DSM 9187]
9
MGKALVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTSGSASTSANKEGVKKATKPSAADKAQKEYSSLVSRMGIDPEHGWKARYEILPGKEKVVAELRALAAQADIIYLATDLDREGEAIAWHLRELIGGDESRFKRVVFNEITKTAIQEAFSHPGLLNIERVNAQQARRFLDRVVGYMVSPLLWKKIARGLSAGRVQSVALRLIVEKERDIKAFVPEEYWDIHADTQTPTRETLRLQVTAQQGKTFDPKNEQQAMAAVQTLKNAAYQVRDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEAVVTVREYIEQQFGKKYLPKEPLTYGSKANAQEAHEAIRPSNVEVKADTLKDMEADAVRLYDLIWRQFVACQMTPAQYDTSTLTVTAADFELKAKGRILRFAGWTKALPPMGRKGDDIELPAVNAGDVLQLIKLDPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLVESFADLMSYDFTAQMENSLDNIAQGKLDWHKQLDEFYAEFKSDLQKAEGEAGGMRSNQMVLTDIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKQTINLVPGDEYIAADSEDGEVDALLAMHRCKKCGTAMDSYVLDATRKIHICGNNPDCDGYEIETGQFRLKGYEGPVVECDRCGSDMQLKTGRFGKFMACTNAECKNTRKILKNGDVAPPKEDPVFLPELKCSKSDAHFVLRDGAAGLFMAASTFPKSRETRAPLVAELLRFKDRLAPKHQYLAEAPVADPEGNPTIVRFSRKTKEQYVASEVEGKATGWAAYYTNGRWQVSAGKGK
(192) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Gallinarum/pullorum str. RKS5078]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(203) DNA topoisomerase 1 [Psychrobacter sp. PRwf-1]
9
MAKTTAKKTTSTPAASAKGKSLVIVESPAKAKTINKYLGDDFIVRSSIGHVRDLPTSSGVKKKATKTDEKLSKEDKAQQALVRRMGIDPEHGWKAVYEVLPNKTKVIKELKALAKDADKIYLATDLDREGEAIAWHLREVIGGDDSKYQRVVFNEITKSAIQNAFKEPGKLDIDRVNAQQARRFLDRVVGFMVSPLLWQKIARGLSAGRVQSVATRLVVEREREIRAFIPEEYWQIHADTTMKGSENANVAADTPIRLEAVKQAGKVLKLGNKAQTDAVLAVLKPATFVVKEREEKPTQSKPSAPFITSTLQQAASTRLGFPVKKTMMLAQRLYEAGHITYMRTDSTFLSNDALASVRGFIEENYGSKYLPEKPNFYGSKQNAQEAHEAIRPTNANLKSTQLKGVDRDAIRLYELIWRQFVACQMLPAKYKSVNLLVEAGDVELKARGRTMTFDGFTKVMPPAKTDDTLLPDVKQGDELNLIKLDPSQHFTKPPARYTEASLVKELEKKGIGRPSTYASIISTIQDRGYVRLENKRLYAEKMGDIVTDRLTESFPELMDYTFTAGLEDELDHVAQGDQDWKAVLDDFYGDFKTKLEHAKDKDGMRPNDPTDVPDVHCDLCGRPMQLRNGSTGVFLGCTGYNLPPKERCKGTKNLMPVEAFANLDDSEIDESAEVKELMEKKRCPKCSTAMDGYIVDGGLKLHICGNNPDCDGYLLEEGMFEVPGSDAPTIDCNKCDGQMELKTGRFGPYFACNKCDNTRKVLKNGEPAPPRMDPIDMPELKSTKHEDHFILREGAAGLFLAASKFPKVRETRPPKLSELRTIKDKMDDKFQYLFDGPDQDPEGNPTILRWSRKQKEQYIGSESLKTGKATRWGVYWRKGEWVEE
(226) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(253) DNA topoisomerase 1 [Dickeya dadantii 3937]
9
MGKALVIVESPAKAKTINKYLGNDFVVKSSVGHVRDLPTSGSGSASKKSAEANGEKAKKAVKKDEKTALVNRMGVDPYRGWQANYEILPGKEKVVSELKTLAQNADHVYLATDLDREGEAIAWHLREIIGGDDKRFSRVVFNEITKNAIRQAFENPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWELHADLLANPDIALQMQVTHHNGKPFRPVNQAQTQAAVSLLEKASYVVAEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALAMARDYIQDEFGKRYLPEAPNLYTSKENSQEAHEAIRPSDVKVLADQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLVVSAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIDVGQSLSLEKLLPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMENSLDLVANSQAEWKAVLDEFFAEFSKQLETAEQEPDEGGMKPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLIPEAEVLNVLEGDEAETNALRARRRCSKCGTAMDSYLIDNQRKLHVCGNNPSCDGYEIEQGEFRLKGYDGPVVECEKCSSEMHLKMGRFGKYMACTNESCGNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFRDRLPEKLRYLAEAPVTDPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYVDGKWVESSR
(284) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(305) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFLPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEEIYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(307) DNA topoisomerase 1 [Escherichia coli NA114]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(317) DNA topoisomerase 1 [Sodalis glossinidius str. 'morsitans']
9
MGKALVIVESPAKAKTINKYLGKDYVVKSSVGHIRDLPTSGSASQKSTDASKKKKGKPDAQLALVNRMGIDPYHGWKARYEILPGKEKVVTELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITRNAITQAFEQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELHADLKTAQAAPLAMQVTHQREKPFKPVNQQQIQAALDGLENADYVVSDRDDKPTSSKPGAPFTTSTLQQAASTRLGYGVKKTMTLAQRLYEAGHITYMRTDSTNLSQDALNMARGYISASFGSPYLPKQANDYASKNNAQEAHEAIRPSDVNALAEQLKDMEADVQKLYQLIWRQFVACQMTPAQYDSTTLTVTAGEFQLRARGRTLRFDGWTKVMPALRKGDEDRTLPAVEAGQTLTLIKLLPSQHFTKPPARYSEASLVKELEKRGIGRPSTYVSIISTIQDRGYVHAENRRFYAEKMGEIVTDRLEENFRELMNYNFTAKMEDTLDQVAANQQEWKQVLDAFFQEFSQQLENAEKDPEDGGMRPNQMVMASINCPVCGRKMGIRTASTGVFLGCSGYALPPKERCKNTINLIPESETLNVLEGDDAETNALRARRRCGKCGTAMDSYVIDGQRKLHVCGNNPLCDGYDIEQGEFRIKGYDGPVVECEKCGADMHLKLGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELLCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVAELARFRDRLPENLRYLADAPVKDDEGDSTLVRFSRKTKQQYVSSEKDGKATGWTAFYIDGEWQVTKK
(325) DNA topoisomerase 1 [Shewanella loihica PV-4]
9
MEPIYRILRLFGADHSMGKSLVIVESPAKAKTINKYLGKDYIVKSSVGHIRDLPTSSSSDASSSTKSPAEVRKMSTEEKAKYKADKAKKALVARMGVDPERGWKAKYQTLPGKEKVVKELQSLAENADHIFLATDLDREGEAIAWHLQEVIGGDPERYQRVVFNEITKSAIQEAFSHPSQLNTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVATRLVVEREGEIKAFVPEEFWDIHAELTTLGNEGLKMQVAKFKGDNFNPVNEAQAMVAVNALKDSKYQVSSREVKATSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVRDMIGKEYGDKYLPDAPIRYGSKEGAQEAHEAIRPSDVNVSATSLSDMERDAQRLYELIWRQFVACQMTPAKYDATRLTVTAGDYELKASGRTLKFDGWTRVQTALKKKNEEDNTLPMVAEGDVLALEELLPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSESLIGSFEELMSYDFTAGMEQTLDNVAQGQLEWKKVLDNFYKGLTAQLEKAELPPEEGGMRPNEMVLTDIACPTCGRPMGIRTGTTGVFLGCSGYALPPKERCKTTMNLTPGEEAVSENSEDAETDALRAKHRCDVCGTAMDSYLIDEKRKLHVCGNNPICGGYEVEQGQFKIKGYEGPIIECDRCGNDMELKNGRFGKYFGCTNSECKNTRKLLKNGEVAPPKEDPIHLPELKCTKSDGYFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPVADEDGNKAVVRFSRKTKEQYVATEIDGKATGWTAKFVGGKWVSEAKAKPKAKKKA
(341) DNA topoisomerase 1 [Vibrio furnissii NCTC 11218]
9
MEEKARLKKEKDKAALIKKMGVDPYHGWEANYQILPGKEKVVAELQKLAKDADSVYLATDLDREGEAIAWHLREIIGGDEERYKRVVFNEITKNAIQQAFQQPGELNMDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFVPEEFWDIHADTKTPSKEDFRLLVAQKDGVAFKPSNEAEAMAAMSVLQKAAYEVCKREDKPTSSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSSEAVDAVRQYITSEFGEAYLPGKPNVYGSKEGAQEAHEAIRPSDVAVKADALEGMEADAHKLYALIWNQFVSCQMTPAKYDSTTVSVKAAEYTLKAKGRILKFDGWTRVQRPLGKNEDQILPAVEVGETLSLEKLDPKQHFTKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFYAEKMGEIVTDRLDDSFEDLMNYDFTARMEQKLDQIAEGETSWKGVLDNFFEDFSHNLETAEQDEDHGGMKPNHIVMTNILCPTCSRPMGIRTASTGVFLGCSGYALPPKERCKTTINLGDEDGIINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKLHVCGNNPNCEGYIVEQGEFKVKGYDGPVVECDKCGSDMVLKNGRFGKYMDCTSETCKNTRKILRNGEVAPPKEDPVHFPELPCENSDAYFVLRDGASGLFLAASNFPKSRETRAPLVEELAKYKDRLPEKYQYLADAPAQDPDGLKAVVRFSRKSKEHYVRTETDGKPSGWTALYNDGHWDITDKRKKAK
(342) DNA topoisomerase 1 [Shewanella woodyi ATCC 51908]
9
MEPIYKFLRLFGADHSMGKSLVIVESPAKAKTINKYLGKDYIVKSSVGHIRDLPTSSTAEANVATKTPAEVRKMSPEEKAIYKSKRAKQALVTRMGVDPENGWKAKYQTLPGKEKVVKELQALAASADHIFLATDLDREGEAIAWHLQEVIGGDASRYQRVVFNEITKSAIQDAFSKPATLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVATRLVVEKEGEIKAFVPEEFWDIHANLTTLANDALKMEVVKFQEKAFNPVNELQAQTAVSALSQSSFVVAAREDRATSSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEAVDNVREMIGKEYGDKYLPDAPIRYGSKEGAQEAHEAIRPSDVSVHAAGMKDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVKAGEYELKATGRTLRFDGWTRVQTAVKKKNEEDNTLPVVAKGDVLSLEELLPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSESLIGSFKELMSYDFTASMEQTLDDVAQGELEWKKVLDGFYQDLTKQLDQAELAPEEGGMRPNEMVLTDIKCPTCGRPMGIRTGTTGVFLGCSGYALPPKERCKTTMNLTAGEEAVSENSEDAETDALRAKHRCGVCGTAMDSYLIDETRKLHVCGNNPICGGYEVELGQFKIKGYEGPIIECDRCSNDMELKNGRFGKYFGCTNSECKNTRKLLKSGEAAPPKEDPIHLPELKCTKSDGYFVLRDGAAGIFMAASTFPKSRETRPPLVEELVKYRELLWPKYAYLADAPVEDDDGNKSTVRFSRKTKEQYVATEVDGKATGWTSKFVDGKWVTESKKKAKPKAKPKAKAKAKS
(346) DNA topoisomerase 1 [Halomonas elongata DSM 2581]
9
MGKSLVIVESPAKAKTINKYLGNEYIVKSSVGHIRDLPTSGSGKAASDPKERARQAAATRKMSAEEKAEYRKRKAHDQLIRRMGIDPDHGWEAEYVVLPGKEKVVAELKKLADKADNVYLATDLDREGEAIAWHLRETIGGDESRYRRVVFNEITKNAIQEAFEDPGQLNMPRVEAQQARRFLDRVVGFMLSPLLWAKIARGLSAGRVQSVAMRLIVEREREIRAFVPEEFWDVHADLSPRDGNGETVRFELARQDGKTFRPTSETETLERIAALREANLVITSREDKPTRSRPNAPFITSTLQQAASGRLGFSVKKTMTLAQRLYEAGYITYMRTDSTNLSQEAVAGARDYIGEAYGKPYLPETPNRYTSKEGAQEAHEAIRPSDVTRRAGDLAGMERDAERLYELIWRQFVACQMTPAEYLSTTLTVEASGYELRAKGRVLKFDGYTRVMAPMGRKDEDQSLPDLAEGTALTLEALDPQQHFTKPPARYTEASLVKELEKKGIGRPSTYASIISTIQDRGYVRLENRRFYAEKLGDIVTERLKESFPDLMDYSFTARMEDSLDEVAEGQRRWRELLDAFYAEFREELKVAESEEGMRPNQPVPTDIECPTCGREMQIRTASTGVFLGCSGYNLPPKERCKTTMDLLPGDEAVAADAGEEAETDALRAKHRCPKCGTAMDSYLIDEQRKLHICGNSPDCDGHEVEEGRFRIKGYDGPTIECDKCGSEMQLKSGRFGKYFGCTNDTCKNTRKLLRNGEVAPPKMDPIPMPELACQKVEDHYVLRDGASGLFLAASKFPKNRETRPPLVVELQAHADELPEKYRYLLDAPSADPDGRPAQIRFSRKTKEQFVMTDDNGKATGWKATFADGRWQVEDKRK
(355) DNA topoisomerase 1 [Pseudomonas fulva 12-X]
9
MGKSLVIVESPAKAKTINKYLGSQYVVKSSIGHIRDLPTSGGAATKEPAKRGKAAAGEAPALSPKEKAKRQLFARMGVDPEHGWKAKYEILPGKEKVVEELRRLAKEADTIYLATDLDREGEAIAWHLRESIGGDDSRYKRVVFNEITKKAIQEAFSAPGELDINRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREKEIRAFVPEEYWEVHADLGTAKDAQVRFEVVRENGAAFKPLNEAQAMAALATLKASSYSVAKREDKPTSSKPTAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADAIEMVRGFIDKEYGKKYLPEKPNFYSSKEGAQEAHEAIRPSDVNLRPTQLSGMERDAERLYELIWRQFVACQMPPAEYLSTTVTVNAAQFELRAKGRILKFDGYTRAQPQLSKPGDDAMLPEMKESESLKLIKLDPSQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVALHNRRFYSEKMGDIVTERLSESFSDLMDYGFTAGMEENLDDVAQGEREWKHLLDEFYGDFKKKLEVAADGDNGMRANTPTLTDIPCRECGRPMMIRTASTGVFLGCSGYALPPKERCKATINLVPGDEIAADDEGESESRVLLGKHRCPICATAMDAYLLDETRKLHICGNNPDCAGYEIEQGQFRIKGYEGPSLECDKCGSQMQLKTGRFGKFFGCTNSECKNTRKLLRNGEPAPPKMDAVKMPELKCEKVDDTYVLRDGASGLFLAASQFPKNRETRAPLVLELLPHKDEIDPKYHFLFDAPAKDPEGRAAVIRYSRKTKEQYVQTEVDGKPTGWKAFFDGGKWKVEDKR
(377) DNA topoisomerase 1 [Erwinia sp. Ejp617]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKTTKKVKKDEKTALVNRMGVDPFHGWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRQAFDRPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVDREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINREQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYVEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMEADAQKLYQLIWRQFVACQMVPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKAVLDQFFGDFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALSPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYDIEQGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAKDADGNKAVVRFSRKTKQQYVSTEKDGKASGWSAFYVDGKWEVTKK
(411) DNA topoisomerase 1 [Pseudomonas fluorescens F113]
9
MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSASASKEPAAKRGKAAAGEAPALSPKDKARKQLVSRMGVDPEHGWKARYEILPGKEKVIEELRRLAKDADTIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIQEAFSQPGELDIDRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWEVHADLGTAKGATVRFDVAREKGEAFKPLNEAQAMAALEKLKASSYSIVKREDKPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSVDAVAMARTYIESEFGKKYLPDTPNVYSSKEGAQEAHEAIRPSDANTEPSKLSGMERDAERLYELIWRQFLACQMLPAQYLSTTVSVGAGDFELRAKGRILKFDGYTRVMPQITKPGDDDVLPDMAQGDVMKLIKLDPTQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVALHNRRFYSEKMGDIVTERLSESFSNLMDYGFTAGMEENLDDVAQGERDWKNVLDEFYGDFKKKLEVAESPDSGMRANQPVMTDIPCLTCGRPMQIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEGESESLVLRGKHRCPICSTAMDAYLLDEKRKLHICGNNPDCAGYEIEEGTYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPTCKNTRKLLKSGDAAPPKMDPVKMPELKCEKVNDTYILRDGASGLFLAASQFPKNRETRAPLVMEIVPHKDEIDPKYHFLCAAPQKDPEGRPAVIRYSRKTKEQYVQTEVDGKPTGWKAFYDGGKWTVQDKS
(413) DNA topoisomerase 1 [Azotobacter vinelandii DJ]
9
MGKSLVIVESPAKAKTINKYLGSQYVVKSSIGHIRDLPTSGSASTAKEPAKRGKGVAEGPALSPRDKAKRQLFARMGVDPEHGWQAHYEILPGKEKVVDELRRLAREADTIYLATDLDREGEAIAWHLRESIGGDEERYKRVVFNEITKKAIQEAFSQPGDLDINRVNAQQARRFLDRVVGYMVSPLLWQKIARGLSAGRVQSVAVKLIVEREREIRAFIPEEFWEVHADLGTARGDKVRFEVAREQGEVFRPLNEAQAMAALEKLKASSYQVLKREDKPTRSKPSAPFITSTLQQAASNRLGFSVKKTMMMAQRLYEAGYITYMRTDSTNLSADALEMARGFIDSEFGGKYLPAKPNVYTSKEGAQEAHEAIRPSDVNLRPNQLAGMERDAERLYELIWRQFVACQMPPAEYLSTNVSVQAGDFELRAKGRILKFDGYTRVLPQLAKPGEDDVLPEMSEGELLDLLKLDPSQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQERGYVTLQNRRFHSEKMGEIVTERLGESFANLMDYGFTASMEEHLDDVAQGERDWKNLLDEFYGDFRRKLEAAESSEAGMRANQPTLTDIPCRECGRPMMIRTASTGVFLGCSGYNLPPKERCKATVNLIPGDEIAADDEGESESLLLRHKRRCPKCGTAMDAYLLDERHKLHICGNNPDCPGYEIEEGQYRIKGYEGPTLECDKCGSEMQLKTGRFGKFFGCTNAACKNTRKLLKNGEPAPPKMDAVKMPELRCEKVDDVYVLRDGASGLFLAASQFPKNRETRAPLVLELLPHRDEIDPKYHFLLEAPSHDPEGRPAVIRFSRKTKEQYVQSEVEGKPSGWRAFHRDGRWVVEDKH
(424) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(437) DNA topoisomerase 1 [Moraxella catarrhalis RH4]
9
MATSKKTTTKAEAALTKANARGKSLVIVESPAKAKTINKYLGKDYVVRSSVGHVRDLPVGGSATKTNKTQDVGLSREEKAQKALVRRMGVDPEHDWAAVYEILPNKTKVIRELKALAKEADKIYLATDLDREGEAIAWHLKEVIGGSDDKYSRVVFNEITKTAIQTAFEHPDQLNIDRVNAQQARRFLDRVVGFMVSPLLWAKIARGLSAGRVQSVATRLVVEREREIRAFVPVEYWKIHTNNTAAGETLNLEAVKKNGKTLKLGNKAQADEVVLALGSSDFIVSAIEEKPTQSRPSAPFITSTLQQAASTRLGFSVKKTMILAQRLYEAGHITYMRTDSTFLSQDALNLVREYITDHFGDDYLPQKPNFYGNKQNAQEAHEAIRPSHVLVKSSQLTGMERDAQRLYELIWRQFVACQMMPARYQSVNLMVAAGDIELKAKGRTLVFDGYTKVQPPAKTDDILLPAVKVGEKLPLIEILPTQHFTSPPARYSEASLVKELESLGIGRPSTYASIISTIQERGYVKLENKRLYAEKMGDIVTERLVESFPDLMDYAFTAGLEDKLDEVAVGEEDWKTVLDRFYHDFKQKLDYAKTTDGMRPNNPTNVPDIHCDLCHRPMQIRTGSTGVFLGCTGYNLPPKERCKGTKNLMPVSAFEFDADDDSAEVNALMEKKRCPKCNTAMDGYIVDGGLKLHICGNNPDCDGHVLEKGVFEIGGATSDTPTIDCDKCDGQMELKTGRFGAYFACRKCDNTRKVLKNGQAAPPRMTPIDMPKLRSQKFDDHYVLREGAAGLFLAASKFPKVRETRPPKLSELREIKDQLEPKFYYLFDAPDTDDVGNPTILRWSRKNQEQYVGSEKDGKATRFALVWRDGAWVQA
(438) DNA topoisomerase 1 [Moraxella catarrhalis RH4]
9
MATSKKTTTKAEAALTKANARGKSLVIVESPAKAKTINKYLGKDYVVRSSVGHVRDLPVGGSATKTNKTQDVGLSREEKAQKALVRRMGVDPEHDWAAVYEILPNKTKVIRELKALAKEADKIYLATDLDREGEAIAWHLKEVIGGSDDKYSRVVFNEITKTAIQTAFEHPDQLNIDRVNAQQARRFLDRVVGFMVSPLLWAKIARGLSAGRVQSVATRLVVEREREIRAFVPVEYWKIHTNNTAAGETLNLEAVKKNGKTLKLGNKAQADEVVLALGSSDFIVSAIEEKPTQSRPSAPFITSTLQQAASTRLGFSVKKTMILAQRLYEAGHITYMRTDSTFLSQDALNLVREYITDHFGDDYLPQKPNFYGNKQNAQEAHEAIRPSHVLVKSSQLTGMERDAQRLYELIWRQFVACQMMPARYQSVNLMVAAGDIELKAKGRTLVFDGYTKVQPPAKTDDILLPAVKVGEKLPLIEILPTQHFTSPPARYSEASLVKELESLGIGRPSTYASIISTIQERGYVKLENKRLYAEKMGDIVTERLVESFPDLMDYAFTAGLEDKLDEVAVGEEDWKTVLDRFYHDFKQKLDYAKTTDGMRPNNPTNVPDIHCDLCHRPMQIRTGSTGVFLGCTGYNLPPKERCKGTKNLMPVSAFEFDADDDSAEVNALMEKKRCPKCNTAMDGYIVDGGLKLHICGNNPDCDGHVLEKGVFEIGGATSDTPTIDCDKCDGQMELKTGRFGAYFACRKCDNTRKVLKNGQAAPPRMTPIDMPKLRSQKFDDHYVLREGAAGLFLAASKFPKVRETRPPKLSELREIKDQLEPKFYYLFDAPDTDDVGNPTILRWSRKNQEQYVGSEKDGKATRFALVWRDGAWVQA
(444) DNA topoisomerase 1 [Haemophilus ducreyi 35000HP]
9
MGKSLVIVESPAKAKTINKYLGSDYIVKSSVGHIRDLPKSGSEKAEKVKPISTKGLTAEQKAKVKADKARAALVKRMGIDPYHDWKANYQILPDKDKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGKEEHFSRVVFNEITKNAIQKAFEKPEQLNLDRVNAQQTRRFLDRIVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWDILANTLAENGRLPLALTSYKGKKFVAKNQTEADNAVKALQCCEFVVSDIDKKPTSSKANAPFITSTLQQTASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALTMVREYVENHFGTDYLPAKPNFYSSKENAQEAHEAIRPSDVRVKMSDLKGMEKDAERLYDLIWRRFVACQMPPARYDSTSLTITAGDYELKAKGRVLRFDGWTKVLPIQGKTAEDQELPAVMLNEKLTLAEIIPSQHFTKPPAHFSEAALVKELEKRGIGRPSTYATIISTIQERGYVRTENRRFYAEKMGEIVTDRLDESFSDLMNYDFTANMEETLDQIAKGNKNWKEALNSFFSDFSEQLSKAELDELEGGMKPNSLVVTDIDCPTCARKMAIRTASTGVFLGCTGYALPPKERCKTTMNLILEAELFNVLDEESEAKALLARKRCPKCGSAMDSYIIDPTRKLHICGNNPNCDGHIVEQGSFKIKGYDGPIVECDKCGADMHLKLGRFGKYMACTACDNTSKILKNGEVAPPREEPTHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRAPKVAELALYRDRLPAKLQYLADAPQQDPEGNQAIIRFSRKEKRQYVTSEKEGKATKWIVDFIDGKWLERHK
(448) DNA topoisomerase 1 [Alteromonas sp. SN2]
9
MAKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTKALGKVEPKKPAKELKTYSEEDKQEYLRRHEYLKLVDRMGVDPEQNWKAHYQVLQGKEKVVNELKRLAKDADTIYLATDLDREGEAIAWHLQELLGSKGKTYQRVVFNEITKNAIQEAFSDPGEVNVARVNAQQARRFLDRVVGFMVSPLLWKKIARGLSAGRVQSVAVRLVVDREREIKAFVPEEFWDIHADLTSEQKAALRMLVAKHEGKAFKPVNKAQADKALEDLNGAKYLVESRESKPTSSRPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQEALDNCRAYIDDNFGSQYLPESPNRYGSKEGAQEAHEAIRPSSVKVNAAHLGDMERDAQRLYELIWRQFVACQMTPAKYDATTIRVGAGNYELTAKGRVLKFDGWTRVQPQLRKKGEEELMLPDVQKGDVLNLNALDPKQHFTKPVARFNEASLVKELEKRGIGRPSTYASIISTIQDRGYVRLENKRFYAEKMGEIVNDRLMENFDDLMSFDFTANMEQQLDDIAEGNKDWKDVLNLFYSDFYGKLLNAEKAPEEGGMRLNQAIPAGITCDKCGREMNVRTASTGVFLGCSGYNLPPKERCTNTMNLTPGDEVVKVDDEEELETEALRAKKRCPICSTAMDSYLVDETRKLHVCGNTPTCEGTLVETGTFKIKGYDGPIIECDKCGSDMELKNGRFGKYFGCTNEECKNTRKLLRNGEAAPPKEDPVDLPELPCEKSDAHFVLRDGASGIFMAAHNFPKSRETRAPKVEELARFRDRISEKFYYLADAPQKDPEGNLAIVRYSRKTKQQYVMSENEAGKATGWSAWYNDGKWETQAASKPAAKTKAKAKKK
(454) DNA topoisomerase 1 [Cellvibrio japonicus Ueda107]
9
MGKSLVIVESPAKAKTINKYLGSDFVVKSSIGHIRDLPTSGNNKPVDTKERARQAAATRKMSAEQKAVYQAQKSKSQLVGRMGIDPENHWEAHYEILPGKEKVVDELKKLAEKADAIYLATDLDREGEAIAWHLREAIGGDESRFRRVVFNEITKTAIQNAFKSPGPIDQNRVDAQQARRFLDRVVGYMVSPLLWEKVARGLSAGRVQSVAVRLVVEREREIRAFIPEEYWTLFADLKAESGQIASFEVKKQGEEAFKPINEAQAMAAVTALQHAAYKVVSREDKPTQSKPTAPFITSTLQQSASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQEAVESCRTYILDNFGQKYLPKEPVAYSSKEGAQEAHEAIRPSSVDVMPNQLSAMERDAERLYGLIWQQFVACQMTPAEYTSTSVVVEAGNYELRTRGRVIRFDGYTRVLPQQAKKDEDVVLPDMKVGQVLPLVKLNPQQHFTKPPARYTEASLVKELEKRAIGRPSTYAAIISTIQERGYVRQENRRFYAEKMGDIVTERLMESFDDLMDYGFTANMEEALDQVAQGDKNWRQLLDEFYADFSQQLDTASRQDKGMRANDPTDTNIPCSLCGRHMQIRTGSTGVFLGCSGYALPPKERCKNTMNLVSGHEVIDADADDEAESRQLRSKHRCKLCNSAMDSYLIDEQRKLHICGNNPDCPGYEVEQGVYRIKGYEGPTIECDKCGSEMQLKTGRFGKYFGCTNADCKNTRKLLKNGEAAPPKVEPIAMPELRCEKVDDHYVLRDGAAGLFLAASQFPKNRETRAPLVAELLPYKNQLDPKYHFLLSAPVSDPEGNKAIVRFSRKTKEQYVQTEVNGKATGWKAFYVNGRWQVQK
(464) DNA topoisomerase 1 [Gallibacterium anatis UMN179]
9
MGKSLVIVESPAKAKTINKYLGNSYIVKSSVGHIRDLPTSGSGNGEKAKPVSTKGLSAEEKAKIKQKKERDALVKRMGIDPYHNWKANYQILPDKEKVVSELKSLAKKSDHIYLATDLDREGEAIAWHLREVIGGEDERFSRVVFNEITKNAITQAFSHPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWQIAVETKNAEQQLLPFEVTHYQSKPLQIKDKQSADKATETLKNSRYIVTEVETKPTQSRAKAPFITSTLQQTASTRLGFGVKKTMLLAQRLYEAGYITYMRTDSTNLSQDALTMARAYISDNFSAAYLPEKPNFYSSKENAQEAHEAIRPSDIQLKADDLQGMEKDAIRLYDLIWRQFLACQMTAANYDSTTVTATADDYTLKVKGRVLRFDGWTKVLPPLGKNAEDRVLPEVKKGEELTLLQVIPSQHFTKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVRTENRRFYAEKMGEIVTDRLNESFPDLMNYDFTANMEDVLDQIAAGKTDWKQQLNQFFADFSTKLSQAELDELEGGMKPNHLVETNIPCPSCGRPMAIRTASTGVFLGCTGYALPPKERCKTTINLIPEAELLNVLDDNSETKALMERKRCPKCGTAMDSYLIDAHRKLHICGNNPNCDGYVVEEGQFKIKGYDGPVVECDKCGADMHLKLGRFGKYMACTQCDNTRKILKNGEVAPPKEDPIPFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRPAKVSELAQYRDRLPEKLQYLADAPQQDPEGNPTVIRFSRKEKRQYVNSEKEGKATKWIADYIDGKWVARAK
(470) DNA topoisomerase 1 [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
9
MGKSLVIVESPAKAKTINKYLGKDYVVKSSVGHVRDLPTSGSASNEPKKPVIRGIKLSEAEKAAKDRNALFSRMGINPTAGWQANYQILPGKEKVVSELQSLAEKADTIYLATDLDREGEAIAWHLREIIGGDDSRYKRVVFNEITKTAIQEAFAQPSELNIHRVNAQQARRFLDRVVGYMVSPLLWKKLARGLSAGRVQSVAVRLIVDKEREIKAFVPVEFWDLNADLLTADKSDLRMEVVSRNGVDFKPVTQAETFAAVAALEGVDYKVVNREDKPTGSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGYITYMRTDSTNLSKEAVEAVREYIGEQYGAAYLPSDPNLYGAKANAQEAHEAIRPSSVLVTAEMLEGMEPDAMRLYDLIWRQFVACQMTPAQYDSSTLTVKAGEFELKARGRTLRFAGWTKALPPMGRKGEDSQLPAVTVGEILKLVKLDPRQHFTKPPARFTEAALVRELEKRGIGRPSTYASIISTIVDRGYVRVESRRFFAEKMGEIVTDRLVENFVELMNYEFTAKMEDKLDGIAEGSLEWKKVLDAFYAEFTQELEKADKAPEEGGMRANQMVLTDIDCPDCGRKMGIRTATTGVFLGCSGYALPPKERCKKTINLVSADEFVSATDGEEAETEALRAKHRCTICGTAMDAYIIDDSRKLHVCGRNPDCDGYEIEKGQFKLKGYEGPSIECDRCGSEMQLKNGRFGKYMGCTNDTCKNTRKILKNGDIAPPKEDPVPLPELKCTQSDAHFVLRDGAAGLFLAASNFPKSRETRAPLVEELKRFKERLSPKHQYLADAPASDPDGNAAIVRFSRKTKEQYVMTEVNGKATGWTAHYDNGKWQESLAKSKKA
(512) DNA topoisomerase 1 [Psychrobacter arcticus 273-4]
9
MTKPTTKKSAAPAADKPKGSPKGKSLVIVESPAKAKTINKYLGDDFIVRSSIGHVRDLPVGASKSAKKPATTKKDDILTKEEKTQQALVRRMGIDPEHDWAAVYEVLPNKTKVIKELKALAKDADKIYLATDMDREGEAIAWHLKEVIGGADSKYERVVFNEITKSAIQNAFKQPSKLDIDRVNAQQARRFLDRVVGFMVSPLLWQKVARGLSAGRVQSVAMRLVVEREHEIRAFIPEEYWQIHADTHIVDNKDKKATDAEQIGIRLEATKQGGKTLKLVNKEQTDKVLDVLKANDFIVKEREEKPTQSRPSAPFITSTLQQAASTRLGFSVKKTMILAQRLYEAGHITYMRTDSTFLSGDALAAVRGYIEDSYGAKYVPEKPTFYGNKQGAQEAHEAIRPSNVNMKSTQLKAVERDAIRLYELIWRQFVACQMLPAKYLSVNLFVAADDVELKARGRTLVFDGYTKVMPPAKTDDNLLPDVKKGDKLTVDKLDPSQHFTKPPPRYTEASLVKELEKKGIGRPSTYASIISTIQDRGYVKLENKRLFAEKMGDIVTDRLTASFPDLMDYTFTAALEDKLDHVAEGDTNWKDVLDNFYGDFKTTLDRAKEKDGMRPNDPTDVPDVHCDLCDRPMQLRTGSTGVFLGCTGYNLPPKERCKGTKNLMPVEAFANLDDAEGDDEAAEVRDLMEKKRCPKCSTAMNGYIVDGGLKLHVCGNNPDCDGYVLEEGKFEVPGSDSPTIDCNKCDGQMELKTGRFGPYFACQQCDNTRKVLKTGEAAPPRMDPIHLPELKSVKHEDYFILREGAAGMFLAASKFPKVRETRPPKLAELREIKDKMEDKFQYLFEGPDEDPDGNPTILRWSRKKKEQYIGSEKNGKATRWGVYWRKGEWVEE
(528) DNA topoisomerase 1 [Pseudomonas aeruginosa NCGM2.S1]
9
MGKSLVIVESPAKAKTINKYLGSQYVVKSSIGHIRDLPTSGSSSSKEPAAKGRKSASEAPALSPKEKARRQLVSRMGVDPEHGWKAKYEILPGKEKVIDELRRLAKDADTVYLATDLDREGEAIAWHLREAIGGDESRYKRVVFNEITKKAIQEAFSQPGELDINRVNAQQARRFLDRVVGYMVSPLLWQKIARGLSAGRVQSVAVKLVVEREREIRAFVPEEYWEVHADLGTAKGANVRFEVTREKGEAFKPLNEAQAMAALEKLKASAYSVAKREDRPTSSRPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADAIGMVRGFIEDEFGQKYLPGKANVYSSKEGAQEAHEAIRPSDVNLKPTQLSGMERDAERLYDLIWRQFVACQMTPAEYLSTSVSVTAGDFELRAKGRILKFDGYTRVLPQQSKPGEDDVLPEMKEGENLKLIKLDPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQERGYVTTHNRRFYAEKMGDIVTDRLNESFANLMDYGFTAGMEEHLDDVAQGERDWKHLLDEFYGDFKKKLEVAEVSEKGMRANQPTLTNIPCRECGRPMMIRTASTGVFLGCSGYSLPPKERCKATVNLIPGDEIAADDEGESESRVLRGKHRCPICSTAMDAYLLDEKHKLHICGNNPDCPGYEIEEGQYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPTCKNTRKLLKNGEAAPPKMDAIRMPELKCEKVDDIYVLRDGASGMFLAASQFPKNRETRAPLVSEIIPHKAELDPKYHYLCDAPQKDPDGRPAVIRFSRKTKEQYVQSEVDGKPTGWRAFYDGGKWKVEDKR
(542) DNA topoisomerase 1 [Enterobacter cloacae EcWSU1]
9
MNMGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVNPWHNWDAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDANVTTPGGDALPLQVSHQNDKPFRPENRDQTMAAVALLEKARYQVLEREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPESANQYASKENSQEAHEAIRPSDVSVLAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDELSLVDLVPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDSLDQVASHQAEWKKVLDSFFSDFTNQLEKAEKDPEEGGMLPNQMVLTSIDCPTCGRKMGIRTATTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELHRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWVEGKK
(543) DNA topoisomerase 1 [Saccharophagus degradans 2-40]
9
MEKSLVIVESPAKAKTINKYLGNKFVVKSSVGHIRDLPTSGGAKSTVDPKERAKQAALTRKMSPEEKAIHREKKSREQLINRMGINPEKNWEARYEILPGKEKVVEELKKLAEEADTIYLATDLDREGEAIAWHLQETIGGDPDRYRRVVFNEITKTAIQKAFEKPSMLDLNRVNAQQARRFLDRVVGYMVSPLLWEKIARGLSAGRVQSVAVRLVAEREREIRAFIPEEYWDIAAQLDTPKGERAGFDVKKYQGNVFRPVNEKEAMEAVERLKASAFKVTSREDKPTQSKPTAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSAEAVETCRGFILDTFGEKYLPEAPISYSSKEGAQEAHEAIRPSDVTRRPDSLTDMERDAQRLYTLIWNQFVACQMTPAQFTSSNIVVTASDYELRARGRVIRFDGFLRVMPAIAKKDEDKILPDVKVGETLNLHQLDPSQHFTKPTARYTEASLVKELEKQGIGRPSTYAAIISTIQDRGYVHVENRRFYADKMGDIVTERLTESFSDLMDYSFTAKMEESLDVVAEGKKDWLSLLNNFYDDFMQKLDAAKAADTGMRRNEPVETNIECTNCGRNMQIRTGTTGVFLGCSGYNLPPKERCKNTMNLVAGEEAVNIDEDDEAESKQLRQKRRCKICNTAMDSYLLDETRKLHICGNNPDCSGYEVEAGSFKIKGYEGPVIECDKCGQDMQLKSGRFGKYFGCTSESCSNTRKLLRNGEAAPPKMDPVKMPELKCEKVDDTYVLRDGASGIFLAASQFPKNRETRAPLVKELLPHKDEIDPKYDFLMKAPLQDNNGLDTIVRYSRKTKEQYVQTEVDGKATGWKAFYEGGKWVISDEQKPKKPAKKAATKTKAKPKAKAKAKKDE
(549) DNA topoisomerase 1 [Xenorhabdus nematophila ATCC 19061]
9
MAKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGAASQKSSISSTDKNKKKVKKDEKTALVSRMGVDPYHDWEANYQILPGKEKVVAELKTLAEKAEHVYLATDLDREGEAIAWHLREVIGGDDARFSRVVFNEITKNAITQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWQLHADLVAKGEIALRMEVTHEKGKPFKPVNAQQTHAAVSLLEKAKYSVIDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALDMARGYISTHFGDKYLPKEGNVYSSKENSQEAHEAIRPSNVEVMAEELKDMEADAQKLYQLIWRQFIACQMMPAKYDSTTLTVQAGNFELRAKGRTLRFDGWTKVMPVLRKGDEDNTLPAIEANTELDLQQLFPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVNDRLEENFNELMSYDFTARMEDQLDHVANNEANWKGVLDEFFSNFSEQLDVASKEPDEGGMRPNPMVITSIDCPTCCRAMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNILEGDDAETNALRARRRCKKCGTAMDSYLIDNQRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGSEMHLKMGRFGKYMGCTNEECKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLHYLAEAPVADPEGNKTVVRFSRKTKQQYVSSEKNGKATGWAAFFVEGSWAVKEK
(568) DNA topoisomerase 1 [Erwinia amylovora CFBP1430]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGTTVKKSTDSTTSKPTKKVKKDEKTALVNRMGVDPFHGWAANYQILPGKEKVVSELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRHAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINRDQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMARGYIEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMETDAQKLYQLIWRQFVACQMMPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNQAQWKAVLDKFFGDFSQQLEQAEKDPEEGGMQPNQMVVTSIECPSCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPVVECEKCGGEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPRVEELQRFRDRLPEKLRYLADAPAEDAEGNKAVVRFSRKNKQQYVSTEKEGKATGWSAFYVDGKWEVAKK
(582) DNA topoisomerase 1 [Pantoea vagans C9-1]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTAKKSADASTDKKVKDASTDKKVKKVKKDEKAALVSRMGVDPYHGWEADYQILPGKEKVVAELKALAANADHIYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVNAALTTPKGDELSMDVTHKGDKAFRPVNRDETYAAVALLEKARYEIVDREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVAMARGYIESNFGKKYLPETAITYASKENSQEAHEAIRPSDVEVVAEKLKDMEADAQKLYQLIWRQFVACQMTPAKYDSSTITAAAGEFKLKAKGRILRFDGWTKVMPALRKNDEDRTLPAVSVGDVLDLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYAAITSTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESNLDQVANNEAQWKAVLDHFFADFTQQLELAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNERKLHVCGNNPECDGYEIEKGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRSGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFKDRLPEKLKYLADAPAADPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWQEAKK
(583) DNA topoisomerase 1 [Marinomonas sp. MWYL1]
9
MGKSLVIVESPAKAKTINKYLGNDFIVKSSVGHIRDLPSGTTATSTPQERAKQAALTRKMSPEEKLEYKSSKARKQLISRMGVDPESNWKAHYEILPGKEKVVDELKRLAKNADTIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIKAAFETPSELDMDRVNAQQARRFLDRVVGFMVSPLLWSKVARGLSAGRVQSVAVRLIVEREKEIRAFVPDEFWELDAMLATPSKEVIKFEAAKYQDKEYRPVNKAQSDEHVARLNDAKYLVSSREDKPTSSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEGGYITYMRTDSTNLSVDAVEALRGYILSKFGEAYLPAEPIRYSSKEGAQEAHEAIRPSDVNVRVDDLQGMEKDAHRLYDLIRSQFMACQMTPAEYTSTTITVTSGDYEFKAKGRILRFDGYTRAMQAVAKKGEDNILPDVGQGEYLTLKELLPEQHFTKPVARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGDIVTERLVDSFSSLMNFSFTAQMEEQLDDIAEGHKDWIKTLNAFYKDFSSVLAKAESPDGGMMPNEPTPTDVECPTCSRPMQIRTASTGVFMSCSGYALPPKERCKATINLTRGDEAIPVDDEEGESKALINKHRCKICGSAMDSYLMDEHRKLHVCGNNPACSGYEVETGAFKIKGYDGPTLECDKCGSEMQLKTGRFGKYFGCTNEGCKNTRKLLKNGEAAPPKMDPVPMPDLACQKVDDHYVLRDGATGLFLAASQFPRKRETRAPLVEELLPYMDQIDPKYHFFAKAPKKDSEGRPAIIRYSRKTKEQYVMTEEEGKPTGWKAFYVGSKWVIEEGKKK
(600) DNA topoisomerase 1 [Haemophilus somnus 129PT]
9
MSKSLVIVESPAKAKTINKYLGNQYVVKSSVGHIRDLPTVGESSGEKAKPISTKGLSAEEKQRIKTEKEQNALVKRMGIDPYHNWEAKYQILPGKEKVVSELKSLAKKVDHIYLATDLDREGEAIAWHLREVIGGEDSRFSRVVFNEITKNAIKQAFEKPEQLNLDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLVVEREREIKAFQPQEYWEISVDSKNSQKRPIRLDVVQFQGKKFEPKNIEQTRSAVDFLQISDYFVKDLEIKPTTSKPKAPFITSTLQQSASTKLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSKDALEMVRNYIVQEFGQAYLLDKPNFYSSNENAQEAHEAIRPSDVKQLADSLEGMERDAVRLYDLIWRQFVACQMPAAKYDSTTVTVQSGDYELKSKGRVLRFDGWTKVLPQSNRNPEDQELPIVKVGEKLSLTKVEPQQYFTKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRVENRRFYAEKMGEIVTDRLNQSFADLMSYDFTANMENILDQIADGKKNWKEELNQFFKDFSQQLTQAELDELDGGMKPNSLVATDIGCPTCNRQMAIRTASTGVFLGCSGYALPPKERCKTTINLIPEAELLNVLDESSETKALMERKRCSKCDTAMDSYLIDTTRKLHICGNNPNCDGYLVEQGEYKIKGYEGPIVECDKCGGEMHLKLGRFGKYMGCTNCDNTRKILKSGEVAPPKEDPVHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRESRPAKVAELAQYQDRLPEKLRYLADAPVKDPEGNEAIIRFSRKEKRQYVTSEKNGKTTKWSAYFVDGKWVENSK
(603) DNA topoisomerase 1 [Pseudomonas putida S16]
9
MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSASASKEPAAKRGKAAGEAPALSPKEKARRQLVARMGVDPDHGWKAKYEILPGKEKVIEELRRLAKDADTIYLATDLDREGEAIAWHLREAIGGDDTRYKRVVFNEITKKAIQEAFSQPGELDIDRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWEIHADLGTAKNAKVRFEVAREKGEAFKPLNEAQAMAALEKLKASSYSVVKREDRPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADALDMARSYIEREFGKQYLPEAPLVYGSKEGAQEAHEAIRPSDVNTHPSKLSGMERDAERLYELIWRQFLACQMPPAQYLSTSVTVAAGDFELRAKGRILKFDGYTRVLPQQSKPGEDDVLPEMVQGEALKLIQIDPSQHFTKPPARFTEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVTLHNRRFYSEKMGDIVTERLSESFSNLMDYGFTADMEENLDDVAQGERDWKNVLDEFYGDFSKKLQTAESNEDGMRANQPTMTNIPCKECGRPMMIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEGESESRVLLGKHRCPICATAMDAYLLDEKHKLHICGNNPDCAGYEIEEGNYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPACKNTRKLLKSGEAAPPKMDKVDMPELKCEKVDDTYVLRDGASGLFLAASQFPKNRETRAPLVLEIVPHKHEIDPKYHFLCDAPQKDPEGRPAVIRYSRKTKEQYVQSEVDGKPTGWKAFYDGNAWKVEDKR
(607) DNA topoisomerase 1 [Chromohalobacter salexigens DSM 3043]
9
MGKSLVIVESPAKAKTINKYLGNDFVVKSSVGHIRDLPTSGSGKNATDPKERARQAAATRKMSPDEKAVYKKQKHWNQLVRRMGIDPEHGWEANYEVLPGKEKVVAELKKLAEKADAVYLATDLDREGEAIAWHLQETIGGDASRYRRVVFNEITKNAIQEAFKTPGDLDLSRVEAQQARRFLDRVVGFMLSPLLWSKIARGLSAGRVQSVAVRLIVEREREIRAFVPEEFWDVHADLLPASGEDTPIRFEVARHQGKAFRPTSEQETLERIAPLRDAALTITERETKPTRSKPNAPFITSTLQQAASGRLGFSVKKTMTLAQRLYEAGYITYMRTDSTNLSQDAVESARAFIGERFGQSYLPDAPNRYASKDGAQEAHEAIRPTEVTQAGDDLAVERDAQRLYELIWRQFVACQMVPAEYLATTLTIEAEGFELKARGRVLKFDGYTRVMKPAGKKEEDQSLPDLEEGAEMTLQALDPQQHFTKPAPRYTEASLVKELEKRGIGRPSTYASIISTIQDRGYVKLENRRFYAEKLGDIVTDRLAESFSDLMDYGFTARMEDHLDEIAAGNREWRELLDAFYAEFKAKLEHAEAEEGMRPNQPVPTDIDCPTCGRKMQIRTASTGVFLGCSGYNLPPKERCKTTIDLIAGDEAVAADADEEAETEALRAKRRCPECGTAMDSYLIDETRKLHICGNSPDCSGYEIEQGKFRIKGYDGPTIECDKCGSEMQLKSGRFGKYFGCTNENCKNTRKLLRNGEVAPPKMDPIPMPELACQKVEDHYVLRDGASGLFLAASQFPKNRETRAPLVKELKAHRDELPEKYHFLLDAPSEDPDGRDAQIRFSRKTKRQYVMSERDGKASGWRAEYEDGQWRVEDKRK
(620) DNA topoisomerase 1 [Shewanella putrefaciens CN-32]
9
MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSTSEGNEKVKSAAEVKKMSPEEKAQYKKVKDQQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDPSRYQRVVFNEITKSAIQDAFSKPSTLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAQLTTPAEESLRMEVVKHLDSAFEPINEQQALAAVQALSSASFNVISREDKATQSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALESVRDMIGKAFGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVHVEATDLTDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVKAGDYELKATGRTLRFDGWTRVQTVLKKKNEEDNTLPFVSQGDVLALKELQPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSERLVSSFADLMSYDFTASMEQTLDDVARGELDWKKVLDGFYADFTKQLEKAERDPEEGGMRLNQMVMTDIKCPTCGRPMGIRTGTTGVFLGCSGYELPPKERCKTTMNLTPGVEAISENSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPICEGYEVEEGQFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNEECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPICDDEGNKAAVKFSRKTKEQYVATEVDGKATGWSAHYINGKWVSESTAKKSKKA
(634) DNA topoisomerase 1 [Pseudoalteromonas atlantica T6c]
9
MAKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTKALGKVPPKKPAKELKLLSEKKRESYLREHEYRKLVDRMGVDPKNDWEAHYEVLNGKEKVVNELKKLAKNADTIYLATDLDREGEAIAWHLQELIDDPSKDYQRVVFNEITKNAIQEAFSEPGKVNVERVNAQQARRFLDRIVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWDVHADLVTAKQSDLRMQVAKYNDKAFKPVNKAQTDAALSDLEGADYKVVSRDSKPTQSRPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSKEAVDACRDYIGDNFGDKYLPENALKYGSKEGAQEAHEAIRPSNVLLKSESLSEMERDAQRLYELIWRQFVACQMTPAKYDASTIRVSANGYELTAKGRVLKFDGWTKVQNPQRKKGEEDFLLPDVKEGESLNLKQLDPKQHFTKPVARFNEASLVKELEKRGIGRPSTYASIISTIQDRGYVRLESKRFYAEKMGEIVNDRLLENFDNLLSFDFTAKMEQELDEIANGKVSWKDVLNDFYGDFEQKLHLAEKDPEDGGMRLNQAVPTDIACPKCGRPMNVRTASTGVFLGCSGYNLPPKERCTGTMNLTSGDEVIKVDDEEELETELLRAKRRCPICATAMDSYLVDETRKLHVCGNTPTCPGIEVEEGTFKIKGYDGPIIECDKCGSNMELKNGRFGKYFGCTNEECKNTRKLLRNGEAAPPKEDPVDLPELECTKSDAHFVLRDGASGIFMAAHNFPKSRETRAPLVAELARFRDRISPKFYYLADAPAKDPDGNDTLVRYSRKTKQQYVMSENEEGKATGWSAWYTDNKWTVEDKRKKAK
(639) DNA topoisomerase 1 [Actinobacillus succinogenes 130Z]
9
MSKSLVIVESPAKAKTINKYLGTNYVVKSSVGHIRDLPTAGASSGEKAKPISTKGLSVEEKSRIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVAELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKNAIKQAFEKPEQLNIDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEFWEVAAELFTVHKAGIRLDVTAFKGKKFAPKNAEQAQSAVDFLAKSDFIVSDLETKPTSSRPRPPFITSTLQQAASTRLGFSVKKTMMLAQRLYEAGYITYMRTDSTNLSRDALGMVRGYIEQNFGDSYLPPKPNFYSSKENAQEAHEAIRPSDVNVSASHLSGMEKDAERLYDLIWRQFVACQMPAAQYDSTTLTVSAGDYELKAKGRILRFDGWTKVLPQMGKNPEDQELPAVALQEKLELGSVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNQSFAELMNYDFTAGMEDMLDQIANGTKDWKAELNQFFKDFSGQLSQAELDELEGGMKPNSIVPTDIDCPACGRKMAIRTASTGVFLGCTGYALPPKERCKTTMNLIPESELLNVLDSETETKALMARKRCPKCGSAMDSYILDPHRKLHICGNNPNCDGYLVEEGAFKIKGYDGPVVACDKCGADMHLKLGRFGKYMACTNCDNTRRILKNGEVAQPKEEPIHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRESRPAEVAELALYRERLPGKLQYLADAPPKDPDGNDAVIRFSRKEKRQYVSSTDKNGKQTKWIVDFIDGKWIERSKK
(676) DNA topoisomerase 1 [Pseudomonas mendocina NK-01]
9
MGKSLVIVESPAKAKTINKYLGSQYVVKSSIGHIRDLPTSGSASATKEPAKRGKAVAGEAPALSPKEKAKRQLFARMGVDPEHGWKAKYEILPGKEKVIEELRRLAKDADTIYLATDLDREGEAIAWHLRESIGGDDSRYKRVVFNEITKKAIQEAFSKPGELDINRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVAREKEIRAFVPEEYWEVHADLGTAKNAKVRFEVVREGGAAFKPVNEAQAMAALEKLKASSYSVVKREDRPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSNDAVEMVRGFIGSEYGDKYLPGKPNLYSSKEGAQEAHEAIRPSDVNLRPTQLSSMERDAERLYDLIWRQFVACQMPPAEYLSTSVTVAAGDFELRAKGRILKFDGYTRVLPQQSKPGEDDVLPEMKEGEGLKLIQLDPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVTVHNRRFYAEKMGDIVTERLDESFANLMDYSFTATMEGHLDDVAQGEREWKNLLDEFYGDFKKKLEAAEAGEGGMRANQPTLTDIPCRECGRPMMIRTASTGVFLGCSGYALPPKERCKATINLVPGDEIAADDEGESESRVLLGKHRCPICSTAMDAYLLDETRKLHICGNNPDCTGYEIEQGQYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPSCKNTRKLLKNGEAAPPKMDKVEMPELKCEKVDDTYVLRDGASGLFLAASQFPKNRETRAPLVLEIVPHKHEIDPKYHFLCDAPQKDPDGRPAVIRYSRKTKEQYVQSEVDGKPTGWRAFYDGGKWKVEDKR
(686) DNA topoisomerase 1 [Erwinia billingiae Eb661]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKPAKKVKKDEKAALVSRMGVDPFHGWEADYQILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFTPEEYWELHADLNTPKGTGLPMEVTHQHDKPFRPVNGEQTHAAVSLLEKARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYIETEFGAKYLPKAANVYSSKENSQEAHEAIRPSDVAIQSEQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLTVAAGDFKLKAKGRTLRFDGWTAVMPALRKGDEDRTLPPVEVGEELKLQQLKPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEANFRELMNYDFTAHMEDNLDKVANNEAQWKGVLDQFFADFSQQLEKADKDPEEGGMQPNQMILTSIDCPTCNRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPGCDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGDVAPPKEDPVPLPELTCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFRDRLPEKLSYLADAPVSDEEGNKAVVRFSRKTKQQYVSTEKDGKATGWSAFYVDGKWEVASKATATKAAPVKAAANKATATKATAKKAAKK
(702) DNA topoisomerase 1 [Pantoea sp. At-9b]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTARKSADGEKTKPAGKKVKKDEKAALVNRMGVDPWHGWQADYQILPGKEKVVSELKSLAADADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIRQAFEKPGELNIERVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDADLVTPKGDALAMQVTHQGDKAFRPVNREQTYAAVALLQKARYDVLDREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAIAMARSYIDKNFGANYLPAAPNTYASKDNSQEAHEAIRPSDVAVAAEKLKDMEADAQKLYQLIWRQFVACQMVPAQYDSTTLTVGAGDFKLKAKGRTLRFDGWTRVMPALRKNDEDLTLPPVNVGDVLDLKEVLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDSLDQVANNQAEWKGVLDSFFSDFSQQLDQAEKEPEEGGMQPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNVLEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFADRLPEKLKYLAEAPAADPEGNKTMVRFSRKTKQQYVASEKEGKATGWSAFYVDGSWQEAKK
(710) DNA topoisomerase 1 [Aeromonas salmonicida subsp. salmonicida A449]
9
MGKSLVIVESPAKAKTINKYLGKDYVVKSSVGHVRDLPTSGSGSNEPKKPVIRGIKLSESEKAAKDRNALFSRMGINPTAGWQANYQILPGKEKVVSELQSLAAKADTIYLATDLDREGEAIAWHLREIIGGDDSRYKRVVFNEITKTAIQEAFAQPSELNIHRVNAQQARRFLDRVVGYMVSPLLWKKLARGLSAGRVQSVAVRLIVDKEREIKAFVPVEFWDLNADLLTGDKSDLRMEVVSRNGADFKPVTQAETFAAVAALEGVDYKVVNREDKPTGSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGYITYMRTDSTNLSKEAVEALREYIGEQYGAAYLPAEPNLYGSKAGAQEAHEAIRPSSVLVTAEMLEGMEPDAMRLYDLIWRQFVACQMTPAQYDSSTLTVKAGEFELKARGRTLRFAGWTKALPPMGRKGEDSQLPAVTVGEVLKLIKLDPRQHFTKPPARFTEAALVRELEKRGIGRPSTYASIISTIVDRGYVRVESRRFFAEKMGEIVTDRLVENFVELMNYEFTAKMEDKLDGIAEGSLEWKKVLDAFYEEFTQELAKADRDAEEGGMRANQMVLTDIDCPDCGRKMGIRTATTGVFLGCSGYALPPKERCKKTINLVSADEFVSATDGDEAETEALRAKHRCGVCGTAMDAYIIDDSRKLHVCGRNPDCDGYEIEKGQFKLKGYEGPSIECDRCGSEMQLKNGRFGKYMGCTNETCKNTRKILKNGDIAPPKEDPVPLPELKCTQSDAYFVLRDGAAGLFLAASNFPKSRETRAPLVEELKRFKERLSPKHQYLADAPASDPDGNASIVRFSRKTKEQYVMTEVNGKATGWTAHYDNGKWQESLAKSKKA
(730) DNA topoisomerase 1 [Klebsiella pneumoniae KCTC 2242]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTATKGAKKPKKDERSALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVTHKDDKPFRPVSRDETMAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYISDKFGKKYLPDSANQYASKENSQEAHEAIRPSDVNVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPLVKQGDRLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKEVLNHFFGDFTTQLATAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFFIDGKWTEAKK
(740) DNA topoisomerase 1 [Shewanella pealeana ATCC 700345]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSSSSDAKVVSKTAAEVKKMSPEEKAEYKSLKAKQALVARMGVDPEKGWKANYQTLPGKEKVVKELQTLAASADHIYLATDLDREGEAIAWHLQQVIGGDESRYQRVVFNEITKTAIQDAFSQPSVLDTNMVNAQQARRFLDRVVGFMASPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAELNTLTDDLLKMQVVKFQGKAFSPVNEVEAQTAVSQLSQSSFVVAAREDRATSSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDNVRDMIGKEYGDNYLPESPIRYGSKEGAQEAHEAIRPSNVKVSAASLSDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVKAGDYELKATGRTLRFDGWTRVQTAIKKKNEEDNTLPYVAQGDAVTLKELLPKQHFTKPAPRYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVDNRRFFAEKMGEIVSDSLVGSFEDLMSYDFTASMEQTLDDVAQGKLEWKKVLDGFYKDFTKQLEVAELPPEEGGMRPNEMVITDNIKCPTCGRPMGIRTGTTGVFLGCSGYALPPKERCKTTLNLTPGEEAVSSGEDAETEALRAKHRCGICGTAMDSYLIDEARKLHVCGNNPTCNGYEVEAGQFKIKGYEGPIIECDRCGNDMELKNGRFGKYFGCTNTECKNTRKLLRSGEAAPPKEDPIHLPELKCTKSDAYFVLRDGAAGIFLAASTFPKSRETRGPLVEELVKYRELLWPKYQYLADAPVADDDGNLASVRFSRKTKEQYVATDVDGKATGWTSKFVDGKWVTEAKAKPKPKAKAKPKAKPKAKATKAE
(755) DNA topoisomerase 1 [Enterobacter lignolyticus SCF1]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSATKKSADSASTKTAKKPKKDERGALVNRMGVDPWHDWKAQYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDTRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFVDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDASTTTPSGEVLPLQVSHYLDKPFRPVTRDETMAAVSLLEKARYSVVEREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRGYISDSFGKKYLPESANQYASKENSQEAHEAIRPSDVNVMAEALKDMETDAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDYKLKARGRTLRFDGWTKVMPALRKGDEDRTLPPVKQGDALSLVELQPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKEVLNDFFGDFTRQLETAEKGPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCAKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELHRFRDRLPEKLRYLADAPQEDGQGNKTMVRFSRKTKQQYVASEKDGKATGWSAFFVDGKWQEAKK
(763) DNA topoisomerase 1 [Glaciecola nitratireducens FR1064]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTKALGLVEPKKPAKELSKWTDKKKAEYLKDYEYQKLVDRMGVDPKQNWMAHYQILQGKEKVVAELKKLAKDADTIYLATDLDREGEAIAWHLQELLGSKGKTYQRVVFNEITKNAIQEAFSDPGVVNINRVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWDIHADLSTQKKDALKMLVAKHKGAAFKPINKKQADEAVSALENADYTVTSRESKPTQSRPSAPFITSTLQQAASTRLGYGVKKTMTMAQRLYEAGHITYMRTDSTNLSKDAVEGCRNYIQKNYGDKYFPSNPLTYGSKDGAQEAHEAIRPSNVAVKADSLKEMERDAQRLYELIWRQFVACQMTPAKYDATTIRVEANNYELTAKGRVLLFDGWTAVQPQIKRKGDNELLLPDVKQGDTLKLNELDPKQHFTKPVARFNEASLVKELEKRGIGRPSTYASIISTIQDRGYVKLDSKRFYAEKMGEIVNDRLVENFSDLISFDFTAKMEQRLDDIAHGETKWKSVLDNFYSEFSEQLENAEKSVEDGGMKLNQAVPVDIECSKCGREMNIRTASTGVFLGCSGYNLPPKEKCTNTMNLTPGDEVIKVDDEEELETEVLRAKRRCDKCGTAMDSYLVDENRKLHVCGNAPSCEGVFVEQGTFKIKGYDGPIIECDKCKSNMELKTGRFGKYFGCTNEECKNTRKLLRSGEAAPPKEDPVFLPELECEKSDAHFVLRDGAAGLFLAAHTFPKSRETRAPLVEELARFRDRISPKFYYLADAPKADPDKNPTIVRFSRKTKQQYVMSEDGKGKATGWSAWYENGKWVADDKRKKAKKEPKK
(789) DNA topoisomerase 1 [Vibrio splendidus LGP32]
9
MGKSLVIVESPAKAKTINKYLGKDFVVKSSVGHVRDLPTAGQSTGQKAAAVSTKGMSPEDKARIKKEKDRKALIKKMGINPYQEWEANYQILPGKEKVVAELQKLAENADHVYLATDLDREGEAIAWHLREIIGGDETRYKRVVFNEITKNAIQQAFETPGELNIDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREINAFIPEEFWDVHADTKTAEKTDFRLQVAQKDGVAFKPDNEAQTQAAVSVLEKAQYEVCKREDRPTKSKPSAPYITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSSEAVEAAREYIGSEFGAQYLPPKALVYGSKEGAQEAHEAIRPSSVDVKSEDLNGVDADAHKLYSLIWNQFVACQMTPAQYDSTTVSVKADEYTLKAKGRILKFDGWTRVQRPMGKNEDTILPAVQVGEKLDLIALDPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVEQRRFYAEKMGEIVTDRLDGSFNDLMNYDFTARMEQKLDQIAEGEASWKGVLDNFFEDFTGDLEKADLDEDAGGMKPNHIVETDIECPTCSRKMGIRTASTGVFLGCSGYALPPKERCKTTINLGDEDGIINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKMHVCGNNPNCEGYVVEHGEFKVKGYDGPLVECDKCSSDMVLKNGRFGKYMDCTSEDCKNTRKILKNGEVAPPKEDPVHFPELPCENSDAYFVLRDGASGLFMAASNFPKSRETRAPLVEELVRFKDRISPKFQYLASAPVADPDGKPTVVRFSRKTKENYVRTEVDGKPSGWTALYIDGKWEVTDKRKKPKEK
(801) DNA topoisomerase 1 [Photobacterium profundum]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTGARNAGKKAAAQSTAGLSVEEKARLKKIKDRKSLIGKMGVDPYNDWDAHYEVLPGKEKVVSELQKLAADADFIYLATDLDREGEAIAWHLREIIGGDDARYKRVVFNEITKNAIQQAFEEPGELNIDGVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLIVEREREIKAFTPEEFWDIHANTLTVGKDALRLIVSQQAGKAFRPVNEAQTMAAKSVLDSAEYKVVDREDRPTSSKPSAPYITSTLQQAASTRLGYGVKRTMGLAQRLYEAGYITYMRTDSTNLSNDAVVAAREFIGSEYGENYLPKEAIKYGSKKNAQEAHEAIRPSSVEVQAENLEGMDADAVKLYDLIWRQFVSCQMVPAKYDSSTITVQADEFTLKAKGRILRFAGWTLVQRPSGKNEDTTLPIVHVGDVMILEGVEPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVRVDQRRFYAEKMGEIVSDRLDGSFPDLMDFDFTARMEGNLDKIAEGEKNWKAVLDNFFSDFTTELERAELDEDEGGMKPNNIVVTDIECPTCSRPMGIRTASTGVFLGCSGYALPPKERCKKTINLGDEDGIVNVLEEDVETAALRAKKRCPKCDTAMDAYLIDQDRKLHVCGNNPSCDGYIVEKGEFKLKGYEGPLIECDKCGSDMELKTGRFGKYMGCTNEDCKNTRKILKNGEIAPPKEDPVHLPEIPCTQDSNAYFVLRDGASGLFMAASTFPKSRETRAPLVSELVRFKDRLSPKFYYLAEAPTEDPDGREAVVRFSRKSKENYVRTEVDGKPSGWTGLYVDGKWEITDKRKKPKKEKAEKED
(825) DNA topoisomerase 1 [Aggregatibacter actinomycetemcomitans D11S-1]
9
MSKSLVIVESPAKAKTINKYLGNNYVVKSSVGHIRDLPTVGSSTGEKAKAISTKGLSAEEKQAIKHKKEQEALVKRMGIDPYHSWKANYQILPGKEKVVAELKSLAKKVDHIYLATDLDREGEAIAWHLREVIGGDDERYSRVVFNEITKNAIKQAFEHPEHLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLIVEREREIKAFVPQEYWEVSVLTNTPKGDEIRLDVVQFKGKKFEPKNAEQAQSAVDFLSKSDYVISDLETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMVRGYIEKQYGQTYLPAKPNFYSSKENAQEAHEAIRPSDINVGLDDLAGMEKDAVRLYDLIWRQFVACQMPAAQYDSTTLTVTAGDYSLTAKGRILRFDGWTKVLLQQSKSAEDQALPAVSVNDKLNLSEVQPQQYFTKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNQSFADLMNYDFTANMEDVLDQIASGDKNWKTELNQFFKDFSTQLTKAELDELEGGMRPNNLVETDICCPTCGRNMAIRTASTGVFLGCTGYALPPKARCKTTINLVPEAELLNVLDDASETKALMERKRCPKCGTAMDSYIIDPHRKLHICGNNPNCDGYLVEEGKFKIKGYDGPIVECDKCGGDMHLKLGRFGKYMACTQCDNTRKILKNGEVAPPKEEPIHFPELKCEKSDAYFVLRDGAGGVFMSAHNFPKSRETRAPKVAELALYRERLPEKLSYLADAPQTDPEGSEAIIRFSRKEKRQYVTSEKNGKATKWIVDFVDGKWVERKK
(826) DNA topoisomerase 1 [Psychrobacter cryohalolentis K5]
9
MTKPAAKKSAAPAADKPKGSPKASPKGKSLVIVESPAKAKTINKYLGDDFIVRSSIGHVRDLPVGASKSAKKPATTKKDDSLSKEEKTQQALVRRMGVDPEHDWAAVYEVLPNKTKVIKELKALAKDADKIYLATDMDREGEAIAWHLKEVIGGADSKYERVVFNEITKSAIQNAFKQPSKLDIDRVNAQQARRFLDRVVGFMVSPLLWQKVARGLSAGRVQSVAMRLVVEREHEIRAFIPEEYWQIHADTHIADSKAKKAADAEQIGIRLEATKQGGKTLKLVNKEQTDKVLDVLKANDFIVKEREEKPTQSKPSAPFITSTLQQAASTRLGFSVKKTMILAQRLYEAGHITYMRTDSTFLSGDALAAVRGYIEDSYGAKYVPEKPNFYGNKQGAQEAHEAIRPSNVNMKSTQLKAVERDAIRLYELIWRQFVACQMLPAKYLSVNLFVAADDVELKARGRTLVFDGFTKVMPPAKTDDNLLPDVKKGDKLILDKLDPSQHFTKPPPRFTEASLVKELEKKGIGRPSTYASIISTIQDRGYVKLENKRLFAEKMGDIVTDRLTASFPDLMDYTFTAALEDKLDHVAEGDTDWKDVLDNFYGDFKTTLDRAKEKDGMRPNDPTDVPDVHCDLCARPMQLRTGSTGVFLGCTGYNLPPKERCKGTKNLMPVEAFANLDDAEGDDEAAEVRDLMEKKRCPKCGTAMNGYIVDGGLKLHVCGNNPDCDGYVLEEGKFEVPGSDSPTIDCNKCDGQMELKTGRFGPYFACQQCDNTRKVLKTGEAAPPRMDPIHLPELKSVKHEDYFILREGAAGMFLAASKFPKVRETRPPKLAELREIKDKMEDKFQYLFEGPDEDPDGNPTILRWSRKKKEQYIGSEKNGKATRWGVYWRKGEWVEE
(829) DNA topoisomerase 1 [Glaciecola sp. 4H-3-7+YE-5]
9
MAKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTKALGKVPPKKPAKELKLLSENKRESYLREHEYRKLVDRMGVDPKDDWAAHYEVLNGKEKVVNELKKLAKNADTIYLATDLDREGEAIAWHLQELIGDPSKDYQRVVFNEITKNAIQEAFSEPGKVNVERVNAQQARRFLDRIVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWDVHANLLTAKDSDLRMQVAKYNDKAFKPTNKKQTDTALADLEGAEYKVISRDSKPTQSRPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSKEAVDACRDYIDDNFGAKYLPENALKYGSKEGAQEAHEAIRPSNVLLKSESLSEMERDAQRLYELIWRQFVACQMTPAKYDASTIRVSANGYELTAKGRVLKFDGWTKVQNPQRKKGEEDFLLPDVKEGESLSLKQLDPKQHFTKPVARFNEASLVKELEKRGIGRPSTYASIISTIQDRGYVRLESKRFYAEKMGEIVNDRLLENFDNLLSFDFTAKMEQELDEIANGKVSWKDVLNDFYGDFEKKLHLAEKDPDDGGMRLNQAVPTDIECPKCGRPMNVRTASTGVFLGCSGYNLPPKERCTGTMNLTSGDEVIKVDDEEELETELLRSKRRCPICSTAMDSYLVDETRKLHVCGNTPTCPGIEVEMGTFKIKGYDGPIIECDKCGSDMELKNGRFGKYFGCTNEECKNTRKLLRNGEAAPPKEDPVDLPELECTKSDAHFVLRDGASGIFMAAHNFPKSRETRAPLVAELARFRDRISPKFYYLADAPAKDPDGNDTLVRYSRKTKQQYVMSENEEGKATGWSAWYTDNKWTVEDKRKKAK
(835) DNA topoisomerase 1 [Pectobacterium atrosepticum SCRI1043]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSVSKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWEANYEILPGKEKVVSELKALAENADHIYLATDLDREGEAIAWHLREIIGGDDQRFSRVVFNEITKNAITQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHNGKPFKPVNKEQTHAAVSLLENARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPEAATGYSNKENSQEAHEAIRPSDVGVLADSLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEGLSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALPPKERCKTTINLIPETEVLNVLEGDEAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTGETCSNTRKILRNGDVAPPKEDPVPLPELSCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELDRFKDRLPEKLRYLADAPVADKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(844) DNA topoisomerase 1 [Salmonella bongori NCTC 12419]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGDALPLQVTHQNDKPFRPVSREQTLAAISLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVSVMAESLKDMEADAQKLYQLIWRQFVACQMTSAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKSDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVIRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWVEGKK
(854) DNA topoisomerase 1 [Shewanella piezotolerans WP3]
9
MEPIFRFLKLVGANKYMGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSSSPDAKVVSKTPAEVKKMSPEEKAEYKSLKAKQALVARMGVDPEKGWKAKYQTLPGKEKVVKELQTLAESADHIYLATDLDREGEAIAWHLQQVIGGDESRYQRVVFNEITKSAIQDAFSQPSVLDTNMVNAQQARRFLDRVVGFMASPLLWKKVARGLSAGRVQSVAVRLVVEREGEIKAFVPEEFWDVHAELNTLCDERLKMQVAKFQGKAFNPVNQTEADAAVSALSQSSFVVAGREDRATSSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDNVREMIGKEYGDKYLPEAPIRYGSKEGAQEAHEAIRPSNVKVTAASLSDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVAAGDYELKASGRTLRFDGWTRVQTAIKKKNEEDNTLPVVAKGDTVTLQELMPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVDNRRFYAEKMGEIVSDRLVGSFQDLMSYDFTASMEQTLDDVAQGKLDWKKVLNGFYKDFTKQLENAELPPEEGGMRPNEMVITDIKCPTCGRPMGIRTGSTGVFLGCSGYALPPKERCKTTLNLTPGEEAVSESGEDAETEALRAKHRCGICGTAMDSYLIDETRKLHICGNNPTCEGFEVEAGQFKIKGYEGPIIECDRCQNDMELKNGRFGKYFGCTNSECKNTRKLLKSGEAAPPKEDPIHLPDLKCTKSDAYFVLRDGAAGIFLAASTFPKSRETRGPLVEELVKYRELLWPKYAYLADAPVADDDGNLASVRFSRKTKEQYVATDVDGKATGWTAKFIDGKWVAEAKAKAKPKAKAKPKAKPKAKAKPKAE
(862) DNA topoisomerase 1 [Acinetobacter oleivorans DR1]
9
MANTSRSASQSTASTAPAAHKRALVIVESPAKAKTINKYLGSQFIVKSSVGHVRDLPTGGSKSTEKKPAARTKLTEAEKEQKASQALVNRMGVDPEHGWEAHYEVLPGKENVVAELKKLAKDADAIYLATDLDREGEAIAWHLREVIGGDDSRYHRVVFNEITKNAIQEAFKQPTRLDLNRVNAQQARRFLDRVVGFMVSPLLWEKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWQVFADTQAKKDDIRLEAFRQAGKTLKLKNKAETDALLDVLKGAEYKVAQREDKPTKVNPSAPYITSTLQQAASTRLGFSVKKTMMLAQRLYEAGFITYMRTDSTFLSDDAVSMVRAHIESQYGEKYLPAKPNRYGNKAGAQEAHEAIRPSNVALTGDQLAGVERDAQRLYDLIWRQFVACQMTPAEYLSSTLIVEAANVELKAKGRTLVFEGFTKVRGANKSDDDIILPAIKVGEILKLEKLDPSQHFTKPPARFTEASLVKELEKRSIGRPSTYAAIISTIQERGYVKLENRRLFAEKMGEIVTDRLDESFNNLMNYAFTADLEGQLDKVATGERNWKELLDTFYGDFKKRLTNAQGEHGMRRNQPVEVPAVHCPECSRPMQIRTGTTGVFLGCSGYNLPPKERCKGTLNLTPVESLAALSDDDGAETADLMSKHRCAKCGTAMDSYVIDGGRKLHVCGNNPDCDGFELEEGEFKIKGYDGPTIPCDKCDGEMQLKTGRFGPYFACTSCDNTRKVLKSGQPAPPRVEPIKMEHLRSAKHDDFFVLRDGAAGLFLAASKFPKIRETRAPKVAELRSVAAQLDPKYQFILQAPDVDPEGNPTIVKFSRKNQSQYVGSETPEGKQTKWSLVYQDGKWVEG
(867) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(885) DNA topoisomerase 1 [Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum)]
9
MGKSLVIVESPAKAKTINKYLGSHYVVKSSVGHIRDLPKSGSNNKKNASEIIKKQKTEKKMFQDHQSSLIKRMGIDPYHGWKAQYEILSGKEKVVSELKALAAKADHIYLATDLDREGEAIAWHLREVIGGDPQRFSRVIFNEITQNAIQQAFKKPGELNMNRIHAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPQEYWHLEANLLTPQKIMIPMMVSHFEGEPFKPLNREQTYAAVNDLEDAQYVVLDRKDKPTSSKAGAPFITSTLQQAASTRLGFGVKKTMLMAQRLYEAGHITYMRTDSTHLSQDALSMVRNYIQKHFGNRYLISPAYEYGNKKNAQEAHEAIRPSNVDVFSEQLEDMEPDARKLYQLIWRQFVACQMTPAQYDVTTLIVEAKNYQLRAKGRTLRFDGWTKVMPALRKGDEEETLPIIAVGTSMHLEKLIPSQHFTKPPGRYSEASLVKELEKRSIGRPSTYATIISTVQERGYVRIENRRFYAEKMGEIVTNRLEENFRELMNYDFTARMENALDQIAQHQAEWKKVLDEFFSEFSEQLNIAEKDPSEGGMRPNSMVIMDINCPACGQKMGIRTASTGVFLGCSSYALPPKERCKTTLNLISENEILNLLDGDEAETNALRSRRRCEKCETAMDSYLLDTARKLHICGNNPICDGYQMEQGEFRIKGYEGPIVECDKCAHEMHLKVGRFGKYMGCTNEECKNTRKILRNGEVAPPKENPVPLPELLCEKSDAYFVLRDGAAGLFLAANTFPRSRETRAPRVEELQRFKDRLPEKWHYLVEAPLKDTEGNKTFLRFSRKTKEQYISSEKSGKATGWCAFYIDGQWVEGKKRPLVKS
(896) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQLLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(897) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(914) DNA topoisomerase 1 [Pasteurella multocida 36950]
9
MSKSLVIVESPAKAKTINKYLGSNYVVKSSVGHIRDLPTVGSSNGEKAKAISTKGLSAEEKSAIKQEKDRNALVKRMGIDPYHQWKANYQILPGKEKVVAELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGDDARFSRVVFNEITKNAIQQAFEKPEQLNLDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLVVEREREIKAFQPEEYWEIDVLTQTQAKQALRLAVTQFKGKKFEPKNATQAQSAVDFLQHADYVVSDLETKPTHSRAKAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALKMVRGYIQSHYGESYLPSKPVFYSSKENAQEAHEAIRPSDVNTLAEQLTGMDKDAVRLYDLIWRQFVACQMPAAQYDSTTVTVRAGEYELKAKGRILRFDGWTKVLPTMSKNAEDQVLPDVQLNEKLHLEHVLPEQLFTKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRVENRRFYAEKMGEIVTDRLNQSFTALMNYDFTANMENILDQIANGEKNWKTELNQFFKDFSQQLSQAELDELEGGMKPNSLVPTDINCPTCGRKMAIRTASTGVFLGCSGYALPPKERCKTTMNLIPEAELLNVLDEASETKALMERKRCPKCGTAMDSYLIDPERKIHICGHNPNCDGYVLEQGSFKIKGYDGPIVECDKCGADMHLKLGRFGKYMGCTSCDNTRKILKSGEVAPPKEEPTHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRAPKVAELALYRDRLPEKLRYLADAPQHDPEGNDAIVRFSRKEKRQYVTSEKNGKATKWIVDYLGNQWVERKK
(936) DNA topoisomerase 1 [Rahnella sp. Y9602]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKTADSTEEKTKKKVKKDEKTALVNRMGVDPYHGWEAQYEILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKEPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLLAKKETALQMEVTHHLEKPFKPVNKEQTHAAVSLLEKARYTVVDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVEMVRGYIGENFGDKYLPKAPLQYSNKENSQEAHEAIRPSDVAVISEQLKDMEADAQRLYQLIWRQFVACQMTPAQYDSTTLTVKAGDYSLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIEVGTDLELQQLLPTQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMEDGLDQVANNKAEWKAVLDEFFTEFSKQLETAEKDPEEGGMRPNQMVLTSIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGDEAEANALRAKRRCVKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELKRFKDRLPEKLSYLADAPVADPEGNKSMVRFSRKTKQQYVSSEKDGKATGWTAFFVDGKWVEGKK
(947) DNA topoisomerase 1 [Enterobacter sp. 638]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVDPWHEWEAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREIIGGDETRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANVTTPAGDALPLQVTHENDKPFRPVNRDHTMAAVAQLEKARYQVVEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVTMVRDYIGENFGKKYLPESANQYASKENSQEAHEAIRPSDVSVVSESLKDMETDAQKLYQLIWRQFVACQMNPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPPVNKGDELSLTELLPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDRLDQVANHQAEWKNVLDSFFSDFTEQLAKAEKDPEEGGMQPNQMVLTSIDCPTCSRQMGIRTATTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLRMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPLQDPEGNKTVVRFSRKTKQQYVSAEKEGKATGWSAFFIDGKWVEGKK
(972) DNA topoisomerase 1 [Klebsiella variicola At-22]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSTDSTATKGAKKPKKDERGALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVIHKDDKPFRPVSRDETMAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYISDNFGKKYLPESANQYASKENSQEAHEAIRPSDVSVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPVVKQGDRLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKEVLNHFFGDFTTQLETAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFFIDDKWTEAKK
(984) DNA topoisomerase 1 [Shewanella halifaxensis HAW-EB4]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSSSSEAKVVSKTAAEVKKMSPEEKAEYKSLKAKQALVARMGVDPENGWKAKYQTLPGKEKVVKELQTLAASADHIYLATDLDREGEAIAWHLQQVIGGDESRYQRVVFNEITKSAIQDAFSQPSVLDTNMVNAQQARRFLDRVVGFMASPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAELNTLTDDLLKMQVVKFQGKAFNPVNETQAQTAVSQLSQSSFVVAAREDRATSSKPSAPYITSTLQQAASTRLGYGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDNVRDMIAKEYGDKYLPESPIRYGSKEGAQEAHEAIRPSNVKVSAASLSDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVKAGDYELKATGRTLRFDGWTRVQTAIKKKNEEDNTLPYVAQGDAVTLKELQPKQHFTKPPARFSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSDSLVGSFQDLMSYDFTASMEQTLDDVAQGKLEWKKVLDVFYKDFTKQLEIAELPPEEGGMRPNEMVIADDIKCPTCGRPMGIRTGTTGVFLGCSGYALPPKERCKTTLNLTPGEEAISEGGEDAETEALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPTCNGYEVEAGQFKIKGYEGPIIECDRCGNDMELKNGRFGKYFGCTNSECKNTRKLLKSGEAAPPKEDPIHLPELKCTKSDAYFVLRDGAAGIFLAASTFPKSRETRGPLVEELIKYRELLWPKYQYLADAPVADDDGNLASVRFSRKTKEQYVATDVDGKATGWSSKYIDGKWVTEAKAKAKPKAKAKPKAKAKKAE
(989) DNA topoisomerase 1 [Vibrio sp. EJY3]
9
MGKSLVIVESPAKAKTINKYLGKDFVVKSSVGHVRDLPTAGQSTGEKAAAISTKGMSAEEKARVKKEKDRKALIKKMGINPYHDWEANYQILPGKEKVVSELQKLAKDADYVYLATDLDREGEAIAWHLREIIGGDEERYKRVVFNEITKNAIQQAFQTPGELNMDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREINAFVPEEFWDIHANTKTKDKADFKLLVAQKDGVAFKPVNEAETKAAMSVLEKASYEVCKREDRPTKSKPSAPYITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSAEAVDAVRDFIGSEFGDKYLPASPLKYGSKEGAQEAHEAIRPSSVDVKAEDLQGVDADAHKLYALIWNQFVACQMTPAEYDSTTISVKAEEFTLKAKGRILKFDGWTRVQRPMGKNEDTILPAVQLGDKLNLESLDPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFYAEKMGEIVTDRLDDSFNDLMNYDFTARMEQKLDQIAEGEVNWKSVLDNFFTDFTGDLEKADLDESEGGMKLNHIVMTDIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLGDEEGIINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKMHVCGNNPNCEGYIVEYGEFKVKGYDGPVVECDKCGSDMVLKNGRFGKYMDCTSETCKNTRKILKNGEVAPPKEDPVHFPELPCENSDAYFVLRDGASGLFMAASNFPKSRETRAPLVSELALYEERLPEKFKYLATAPQEDPDGRPAVVRFSRKTKENYVRSEENGKPSGWTALYVDGKWEVTDKRKKAKA
(1024) DNA topoisomerase 1 [Shigella flexneri 5 str. 8401]
9
MRRIPGRIKLGKVNMGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1033) DNA topoisomerase 1 [Shigella flexneri]
9
MGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVHKDHALTLVELTPVHHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGRATGWSAFYVDGKWVEGKK
(1060) DNA topoisomerase 1 [Shewanella oneidensis MR-1]
9
MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSISDGTEKVKSAAEVKKMSPEEKARYKKVKDHQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDPSRYQRVVFNEITKSAIQEAFSKPASLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAQLNTPSSEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKATQSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVREMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVKVEAAALTDMERDAQRLYELIWRQFVSCQMTPALYDATKLTVKAADYELKATGRILRFDGWTRVQTAIKKKNEEDNTLPAVNEGDVLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENRRFYAEKMGEIVSERLVNSFAELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQLEKAELAPEEGGMRLNQMVMTNIKCPTCGRPMGIRTGTTGVFLGCSGYELPPKERCKTTMNLTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLLDEKRKLHVCGNNPVCEGYEVEEGQFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNEECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYREFLWPKYQYLADAPIADDDGNKAVVKFSRKTKDQYVATEVDGKATGWSAHYVNGKWVSESSAKKAKK
(1061) DNA topoisomerase 1 [Edwardsiella ictaluri 93-146]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKGAASAGDKAKTKAKKNERDALVNRMGVDPYHGWQAHYEVLPGKEKVVSELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDGSRYSRVVFNEITKNAIQQAFSQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWELRADLAVGADVSFQAQVTHYNDKPFKPVNAAQSQAAVTALENARFAVREREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRAYIGDNFGAEYLPTDANVYASKDNSQEAHEAIRPSDVSVLADDLKGMEADALKLYQLIWRQFVSCQMTAAKYDASTITVQAADYTLKARGRTLRFDGWTRVLPQLRKGDEDRALPAVESGRALDLLQLQPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRTDNRRFYAEKMGEIVTDRLEENFRELMSYDFTAHMEDGLDRVASAQADWKVMLDGFFSDFSQQLEVAEKPPEEGGMRPNPMVLTCIACPTCERQMGIRTASTGVFLGCSGYTLSPKERCKTTINLVPEAEVLNVLEGDDAETNALRAKRRCPKCGTAMDSYLIDNHRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGAEMHLKMGRFGKYMGCTNEACKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLAEAPQQDAQGNATLVRFSRKTKQQYVSSEKDGKATGWTAFFIDGKWVVSEKK
(1068) DNA topoisomerase 1 [Idiomarina loihiensis L2TR]
9
MAKSLVIVESPAKAKTINKYLGKDFVVKSSVGHVRDLPTRATETIKSKPAAEVRKMSPDAKAKYQKERDYKRLIARMGVDPENDWEAHYEVLQGKEKVVKELKQLAKKSDEIILATDLDREGEAIAWHLRELIGGDDSRYKRVVFNEITKKAIQEAFQHPAELNTDRVNAQQTRRFLDRVVGFMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWDVHADLNTPADESLRMQVMKQAGKNFRPSNKQETDAALALLKKAGYEITGREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSSEAVDACRELITKDFGKNYLPDDPVRYGAKSNAQEAHEAIRPSDVKVKSESLASVERDAQRLYELIWRQFVACQMVPARYDSTTLTATAGDFELKARGRVMRFAGWTKVMPPASSKKDGDATLPDVKKGDALQLEKLNPEQHFTKPPARYGEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFFAEKMGEIVNDRLIENFTELMNYNFTAEMEQALDDIAAGKRDWKETLDKFYADFKERLEKAELEPTEGGMRENSMVLTDIDCPECGRKMGIRTASTGVFLGCSGYNLPPKERCTKTLNLTPGEEAIEVTDEEERETEALRAKKRCPKCGTAMDSYLIDEKRKLHVCGNNPTCDGQLVEEGTFRIKGYDGPTIECDKCGSEMQLKTGRFGKYFGCTNSECKNTRKLLRSGEAAPPKEDPVPLPELPCEESDAYFVLRDGASGIFLSANTFPKSRETRAVTVKELAKFKDRLPEKFKYLAEAPKEDDDGNDAIVRFSRKNKEQYVVTEIKKKQTGWKAFYRSGKWQVEEK
(1076) DNA topoisomerase 1 [Marinomonas mediterranea MMB-1]
9
MGKSLVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTGTTSKSTPQERAKQAALTRKMSPEEKAEYKSKKSRQQLIARMGVDPENNWEAHYEVLPGKEKVVDELKRLAKNADTIYLATDLDREGEAIAWHLREAIGGDEARYKRVVFNEITKNAIKSAFDEPSDLDMNRVNAQQARRFLDRVVGFMVSPLLWSKVARGLSAGRVQSVAVRLIVEREKDIRAFNPEEFWELDALLATASKEQVKFETLKYLGKEYRPTSQIESDEHVARIQNSGFVVSNREDKPTRSKPSAPFITSTLQQAASTRLSFGVKKTMMLAQRLYEGGYITYMRTDSTNLSNEAVEALRDFVGEKYGEAYLPKEPIRYSSKEGAQEAHEAIRPSDVTVTQNMLQGMDNDAHRLYELIRNQFIACQMTPAEYTSTSITVTAGDYELKARGRILRFDGYTRVLTPVGKKAEDMILPDIQKGDTLGLNELLPEQHFTRPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVDNRRFYAEKMGDIVTERLVGSFSQLMNFSFTAQMEEQLDEIAQGEDDWIRTLDAFYADFSNTLTKAEHPEEGMLQNQPTPTDVECPKCGRPMQIRTAATGVFLSCSGYALPPKERCKATINLVSGDEAVAVDDDEGESKALINKKRCKICDSAMDSYLMDETRKLHVCGNNPSCSGYEVEKGAFKIKGYDGPVIECDKCSSEMQLKTGRFGKYFGCTNEECKNTRKLLKNGEAAPPKMDPVAMPDLACQKVEDHYVLRDGATGLFLAASQFPRKRETRAPLVSELIPYMDQIDPKYHFFSDAPVMDNEGRPTVIRYSRKTKEQYVMTEENGKPTGWKAFHQNGKWVVEEGKKKK
(1089) DNA topoisomerase 1 [Pseudoalteromonas haloplanktis TAC125]
9
MGKSLVIVESPAKAKTINKYLGNDFIVKSSIGHVRDLPTSGSGKNKVPATKTPAEVRKLPPEEKAAYKKQRDYSNLVARMGIDPDKGWEPHYEILPGKEKVVQELKKLAENADQIYLATDLDREGEAIAWHLQEIIGGEPAKYKRVVFNEITKNAIQQAFETPGELNTDMVYAQQTRRFLDRVVGFMVSPLLWAKVARGLSAGRVQSVAVRLLVEREREIKAFIPEEFWDIHADVKNAESELRLEVAKQADKPFKPVNEAQASAAVKSLENAEYKVISVDEKPSKSRPSAPLITSTMQQAASTRLGYGVKKTMMLAQRLYEGGYITYMRTDSTNLSKDAVAMCREYVTEQFGEKYLPKDPINYSSKGNAQEAHEAIRPSSVTVLSGHIEGVDADAKKLYELIWRQFVACQMVPAEYDLTTLTVAANDFQLKAKGRVLRFDGWTKVQPAIRKKNEEDQSLPAVTVGETLTLIELDPKQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFFAEKMGEIVTDRLVENFEDLMNFDFTAKMEGRLDDIAEGERIWTEVLDKFYADFSTQLTVAKDEPENGGMRLNEMVETDIECPTCSRKMGIRTASTGVFLGCTGYNLPPKERCTTTMNLVSGDEAVAADSADAEDLETETLMQMKRCPICETAMDSYLIDETRKLHVCGNNPACSGHVVEQGTFKIKGYDGPLIECDKCGADMELKSGRFGKYFGCNNDECKNTRKLLKNGEAAPPKEDPVHITELECEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPKVEELQRFRDRISPKFYYLADAPAQDPDGNLAVVRYSRKNKEQYVMTEVDGKATGWTAHYVAGKWVEEAKKKAAPKKKAAAKKAPAKTKAKAKTKKDDE
(1092) DNA topoisomerase 1 [gamma proteobacterium HdN1]
9
MQKSLVIVESPAKAKTINKYLGKNFIVKSSVGHVRDLPTSGRGETATDSKQRSQKAAATRQLSAAEKEKQKKARAWEALVARMGVDPEHGWKATYQVLPDKQKVVDELRKLAKDCDSIYLATDLDREGEAIAWHLREVIGGDDSRFQRVVFNEITQSAIQEAFASPGRVNENRVNAQQARRFLDRVVGYMVSPLLWAKIGRGLSAGRVQSVAVRLLVEREREIRAFLPEEYWELFAETLTAKKTPLRLEVAREGDKAFRPTDEAQAMAAVKALQHAEYRVANREDKPTRSKASAPFITSTLQQAASTRLGFSVKRTMMLAQRLYEAGYITYMRTDSTNLSAEAVGACREYIEGRYGARYLPDAPNTYASKEGAQEAHEAIRPTDVHLMADQVSGLEKEAQKLYELIWKRFVACQMPPAEYLSTQMTVKAGEFELRAKGRILKFDGHLAVGMPGTRTSDEDIELPDVAVGEVLALKKLDPLRRFTKPPQRFTEASLVRELEKRGIGRPSTYASIISTIQERGYVRVESRRFYAEKMGDIVTDRLSESFDNLMDYGFTARMEEKLDEIAQGNLYWQNVLDEFYSRFSGQLAHAELTEGGMRSNTPVETDIPCPQCGRPMMIRTGATGVFLGCSGYNLPPKERCKGTLNLVPGEEGISATPESDEDESGELEALALRKKHRCKLCATAMDSYLVDEHRKLHVCGNNPDCPGYEVEQGQFKLKGYEGPIVECDKCGSDMQLKTGRFGKYFGCTNEECGNTRKLLRNGEVAPPRESPIPMQHLRCQKHDDFYLLRDGASGLFLAASQFPRHRETRAPTIAELKTVAEQIPEKYQYLLSAPVKDDKGNPAIVRFSRKSREQYVMSESEGKATGWSAVWADGKWVQKPAKE
(1105) DNA topoisomerase 1 [Vibrio vulnificus YJ016]
9
MGKSLVIVESPAKAKTINKYLGKDFVVKSSVGHVRDLPTAGQSTGEKAAAISTKGMSVEEKARIKQKKDRNALIKKMGIDPYHDWAANYQILPGKEKVVSELQKLAKDADFVYLATDLDREGEAIAWHLREIIGGDETRYKRVVFNEITKNAIQQAFQKPGHLNMDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFVPEEFWDIHANTLTQETMPFKLLVAQKSGDAFRPVNEAETKAALAVLQKAQFEVCKREDRPTKSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSQEAVEAVRGYISDEFGSRYLPKAPLVYGSKQGAQEAHEAIRPSDVNIKADALEGVDADAHKLYALIWNQFVACQMTEAEYDSTTVSVKAAEYTLKAKGRILKFDGWTRVQRPLGKNEDTILPAVQVGDKLNLESLEPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFYAEKMGEIVTDRLDDSFNDLMNYDFTARMEEKLDKIAEGDVNWKDVLNQFFADFTTDLGRAEEDEAHGGMKPNHIVMTDIQCPTCSRPMGIRTASTGVFLGCSGYALPVKERCKTTINLGDEEGIINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKMHVCGNNPNCEGYLVEHGEFKVKGYDGPVVECDKCGSDMVLKNGRFGKYMDCTSETCKNTRKILKNGEVAPPKEDPVHFPELPCSNSDAYFVLRDGAAGLFLAASNFPKSRETRVPLVSELARFAERLPEKYKHLAQAPTQDPDGVEAVVRFSRKTKENYVRTEVDGKPTGWTALYVDGKWEVTDKRKNAK
(1116) DNA topoisomerase 1 [Enterobacter asburiae LF7a]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVNPWHNWDAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDANVTTPGGDALPLQVSHQNDKPFRPENREQTMAAVALLEKARYQVLEREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESANQFASKENSQEAHEAIRPSDVSVLAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDELSLVDLVPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDSLDQVASHQAEWKKVLDSFFSDFTNQLDKAEKDPEEGGMLPNQMVLTSIDCPTCGRKMGIRTATTGVFLGCSGYALSPKERCKTTINLVPENEVLNILEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWAEGKK
(1133) DNA topoisomerase 1 [Shewanella frigidimarina NCIMB 400]
9
MESIFFFSRLFGANKTMGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSSTSDGTTVTKTAAEVKKLSPEEKAKYKLIRDKQALVARMGVNPDKGWAAKYQILPGKEKVVKELKALAETADQIYLATDLDREGEAIAWHLQEIIGGDPSRYQRVVFNEITKTAIQDAFSKPSVLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDIHAELNTPTAASLKMQVMKYQSAAFEPINEAQAKVAVDALRDATYVVTAREDKATSSKPSAPYITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSKEAVENLREMIAAEFGDKYLPAEPIRYGSKEGAQEAHEAIRPSNVAVQSASLTDMERDAQRLYELIWRQFVSCQMTPAQYDATRLTVTAGDYELKASGRTLRFDGWTRVQPQVSKKNEEDKTLPVVAKGDKLVLETLSPKQHFTKPAPRYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVDNRRFFAEKMGEIVSERLVGSFKELMSYDFTASMEQTLDDVAQGKLDWKKVLDGFYGDFTKQLLLAELDPDEGGMRPNEMVLTDDIKCPTCCRPMGIRTGSTGVFLGCSGYALPPKERCKTTLNLTPGEEAVSDNEDGETEALRAKHRCGKCGTAMDSYLIDETRKLHVCGNNPSCDGYEVEAGQFKIKGYEGPIIECDRCGNNMELKNGRFGKYFGCTNSECKNTRKLLRSGEAAPPKEDPIFLPELKCTKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVQYRDLLWPKYAYLADAPVEDDEGNKASVKFSRKTKEQYVATEVDGKATGWSSKFIGGKWVSESTKKKAKK
(1136) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Agona str. SL483]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1173) DNA topoisomerase 1 [Marinobacter adhaerens HP15]
9
MGKSLVIVESPAKAKTINKYLGSDFIVKSSVGHIRDLPVSGSGSQSDPKERAKQAAITRKMSPEEKAVHKKRKSREQLVARMGVDPDQDWSARYEILPGKEKVVSELKRLAKSADHIYLATDLDREGEAIAWHLQQTIGGEPEKYRRVVFNEITKRAIQEAFKDPGTLDNNRVNAQQARRFLDRVVGYMVSPLLWAKLARGLSAGRVQSVAVRLIVEREREIRKFVPEEFWQLHADLASAKADQPVRFEVTRHEDKPYRPVNEQQSSDHVSRLKAGTFKVAKREDKPTRSRPSAPFITSTLQQAASNRMGFSVKKTMMLAQRLYEAGFITYMRTDSTNLSQDAINSCRAYIEKQFGDKYRPEKPRVYGSKEGAQEAHEAIRPTEVSRRPADISGLEKDAEKLYDLIWRQFIACQMSDAEFLSTSIVVANGDYELRTRGRIIKFDGFLKAAPQAAKKDEDIALPDIKVDEVLDLKKLDPTQHFTKPAPRYTEASLVKELEKQGIGRPSTYASIISTIQDRGYVRLQNRRFYAEKMGEIVTERLSESFPNLMDFDFTARMEDELDEIAEGDVEWKKVLNDFYGRFRQQLEKAESGEDGGMRANTPTETDIPCPSCGRNMQIRVASTGVFLGCSGYSLPPKERCKTTINLVSGDEVVSADDDVEGEGETRLLRKKRRCPKCGTAMDSYLVDETRKLHVCGNNPDCSGYEVEKGTFRIKGYDGPTLECDKCGSEMQLKTGRFGKYFGCTNAECKNTRKLLKNGEPAPPKMDPVPMPELQCQKVDDTYVLRDGASGLFLAASKFPKNRETRPPLVMEIKPHRKEIDPKYDYLMDAPERDPEGNPTVIRYSRKSKEQYVMSEKDGKATGWSAWYVNGKWQPQDKKK
(1179) DNA topoisomerase 1 [Colwellia psychrerythraea 34H]
9
MAKSLVIVESPAKAKTINKYLGNDFIVKSSVGHVRDLPHSSTGKKVAAKSPAEVRKMEPAAKAKYKAKRDKQALVNRMGIDPDKNWAADYQILPGKEKVVAELKKLADKADIVYLATDLDREGEAIAWHLKEIIGGEDEKFRRVVFNEITESSIQQAFATPGELSMPGVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLVVEKEREIKAFDPKEFWEIAVDTHASTGEVLTLDVTHENGKAFKPTTEKETNAALAILKPADYAVSKREDRPSKSTPSAPFITSTLQQAASTKLGYGVKRTMGLAQRLYEAGHITYMRTDSTNLSKDAVEMCRKYISDSFGDNYLPENAKTYGSKAGAQEAHEAIRPSNVKLEAAFLEGIEADAKKLYELIWRQFVACQMTAARYTVSTLTISAASFDLKAKGRVMQFDGWTIVHPQLSKGDDTHLPDLQVGEALTLDKIEPSQHFTKPPARFGEASLVKELEKRSIGRPSTYASIISTIQDRGYVRLDKKRFYAEKMGEIVTNSLSGSFEKLMSYEFTSNMEQELDEIAGGSADWKGVLDEFYKNFTKQLSKADQPSEDGGMQTNEPVLTDIDCPTCNRKMGIRTAQTGVFLGCSGYALPPKERCTKTMNLTAGEEAVSILAEDAETEALMAMRRCDKCGTAMDSYLIDETRKLHVCGNNPVCDGIEVEKGEFKIKGYDGPILDCDRCESPMELKSGRFGKYFDCTNEECKNTRKLLASGEAAPPKEDPVQLPELECEKSEAHFVLRDGAAGIFLAAHTFPRSRETRAPKVAELQRFRDRISEKFYYLADAPAEDNEGNLSVVRYSRKTKEQYVMTEIATEEGKPKATGWTAKYIDGKWIEDIPKKKVAKKKAAKKPAAKKKAKTAAE
(1194) DNA topoisomerase 1 [Escherichia fergusonii ATCC 35469]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDANTTTPSGDALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPAGNKSMVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEGKK
(1216) DNA topoisomerase 1 [Shigella dysenteriae Sd197]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSYFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPENLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1228) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1232) DNA topoisomerase 1 [Shewanella baltica OS155]
9
MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSTSEGNEKVKSAAEVKKMSPEEKAQYKKVKDQQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDPSRYQRVVFNEITKSAIQDAFSKPSTLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAELSTPAQEALRMEVVKHLDAAFNPINEQQAMAAVQALSAASFTVLAREDKATQSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEAVENLRDMIAKEFGDKYLPAEPIRYGSKEGAQEAHEAIRPSNVHVQAATLSDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVKAGDYELKATGRTLRFDGWTRVQTALKKKNEEDNTLPFVAQGDVLALKELQPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSERLVGSFADLMSYDFTASMEQTLDDVARGELDWKKVLDGFYADFTKQLEKAELDPEEGGMRLNQMVMTDIKCPTCGRSMGIRTGTTGVFLGCSGYELPPKERCKTTMNLTPGVEAISENSEDAETDALRAKHRCSICGTAMDSYLIDEKRKLHVCGNNPICEGYEVEEGQFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIYLPDLKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVQYRELLWPKYQYLADAPVTDDEGNKAAVKFSRKTKEQYVATEVDGKATGWSAHYVNGKWVSETTKKAKKSA
(1234) DNA topoisomerase 1 [Pseudomonas stutzeri A1501]
9
MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSANKEPVKRGKAAAAEAPALSPKEKAKRQLIARMGVDPEHGWKAKYEILPGKEKVIEELRRLAKEADTIYLATDLDREGEAIAWHLRESIGGDDSRYKRVVFNEITKKAIQEAFSQPGELDLNRVNAQQARRFLDRVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFVPEEYWEVHADLATAQQAKVRFEVAREKGEAFKPLNEAQANAALEKLKGASYSVTKREDKPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADAISMVRGFIEGEFGDKYLPEKPNLYSSKEGAQEAHEAIRPSDVNLRPNQLSGMERDAERLYELIWRQFVACQMPPAQYLSTSVTVEAGDFELRAKGRILKFDGYTKVMPQQSKAGEDDVLPEMSKGDAMKLLKLDPSQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVSLHNRRFYSEKMGDIVTERLSESFNNLMDYGFTAGMEEHLDDVAQGERDWKHVLDEFYGDFRKKLEVAESSENGMRANQPTLTDIPCKVCGRPMMIRTASTGVFLGCSGYSLPPKERCKSTVNLIPGDEIAADDEGESESRVLLGKHRCPICSTAMDAYLLDETHKLHICGNNPDCSGYEIEEGQYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNAECKNTRKLLKNGEPAPPKMDAVKMPELKCEKVDDTYVLRDGASGLFLAASQFPKNRETRAPLVRELIPHKDEIDPKYHFLLQAPQQDPDGRPAVIRFSRKTKEQYVQSEVDGKPTGWKAFYDGGKWQVEDKR
(1239) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Newport str. SL254]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFMLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1253) DNA topoisomerase 1 [Vibrio parahaemolyticus RIMD 2210633]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTAGQSTGEKKAAAISTKGMSAEEKARVKKEKDRKALIKKMGINPYHDWEANYQILPGKEKVVSELQKLAKDADCVYLATDLDREGEAIAWHLREIIGGDEERYKRVVFNEITKNAIQQAFQTPGELNMDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREINAFVPEEFWDIHANTKTKDKSDFKLLVAQKDGVAFKPVNETETKAAISVLENASYEVCKREDRPTKSKPSAPYITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSAEAVDAVRDFIGSEFGDKYLPAKPLTYGSKEGAQEAHEAIRPSDVSVKAEDLQGVDADAHKLYSLIWNQFVACQMTPAEYDSTTISVKAAEYTLKAKGRILKFDGWTRVQRPMGKNEDTILPAVQLGDKLSLESLDPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFYAEKMGEIVTDRLDDSFNDLMNYDFTARMEQKLDQIAEGEVNWKAVLDNFFADFTGDLEKAELDESEGGMKLNHIVMTDIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLGDEEGIINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKMHVCGNNPNCEGYVVEYGEFKVKGYDGPVVECDKCGSDMVLKNGRFGKYMDCTSETCKNTRKILKNGEVAPPKEDPVHFPELPCENSDAYFVLRDGASGLFMAASNFPKSRETRAPLVSELARFEERLPEKFKYLTTAPQEDPDGRPAVVRFSRKTKENYVRSEDDGKPSGWTALYVDGKWEITDKRKKAKA
(1290) DNA topoisomerase 1 [Edwardsiella tarda EIB202]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKGAASADDKAKTKAKKNERDALVNRMGVDPYHGWQAHYEVLPGKEKVVSELKSLAEKADHIYLATDLDREGEAIAWHLREVIGGDDSRYSRVVFNEITKNAIQQAFSQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWELRADLAVGAEVSFQAQVTHCNDKPFKPVNAAQSQAAVAALEHARFAVREREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRAYIGDNFGAEYLPADANVYASKDNSQEAHEAIRPSDVNVLADDLKGMEADALKLYQLIWRQFVACQMTAAKYDASTITVQAADYTLKARGRTLRFDGWTRVLPQLRKGDEDRALPAVESGRALDLLQLQPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRTDNRRFYAEKMGEIVTDRLEENFRELMSYDFTAHMEDGLDRVASAQADWKVMLDGFFSDFSQQLEVAEKPPEEGGMRPNPMVLTSIACPTCERQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPEAEVLNVLEGDDAETNALRAKRRCPKCGTAMDSYLIDNHRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGAEMHLKMGRFGKYMGCTNEACKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLAEAPQQDEQGNATLVRFSRKTKQQYVSSEKEGKATGWTAFFIDGKWVVSEKK
(1303) DNA topoisomerase 1 [Yersinia pestis A1122]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSANSAEEKAKKDDKPKKKVKKDEKVALVNRMGVDPYHGWKAQYEILSGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNISRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLVAKGDIPIQMEVTHAHGKPFKPVNREQTHAALTLLENARYKVLDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPATPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQRLYQLIWRQFVACQMPPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSDLDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKAVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPDAEILNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLLELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVVDKEGNKTLVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEAKK
(1341) DNA topoisomerase 1 [Yersinia pseudotuberculosis IP 32953]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSANSAEEKAKKDDKPKKKVKKDEKVALVNRMGVDPYHGWKAQYEILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNISRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLVAKGDIPIQMEVTHAHGKPFKPVNREQTHAALTLLENARYKVLDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPATPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQRLYQLIWRQFVACQMPPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSDLDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKTVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPDAEILNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVVDKEGNKTLVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEAKK
(1343) DNA topoisomerase 1 [Pseudoalteromonas sp. SM9913]
9
MGKSLVIVESPAKAKTINKYLGNDFIVKSSIGHVRDLPTSGSGKNKVPASKTPAEVRKMPPDEKAAYKQQRDYSNLVARMGIDPEKGWEPHYEVLPGKEKVVQELQKLAQNADQIYLATDLDREGEAIAWHLQEIIGGEPEKYKRVVFNEITKNAIQQAFETPGELNTDMVFAQQTRRFLDRVVGFMVSPLLWAKVARGLSAGRVQSVAVRLLVEREREIKAFIPEEFWDIHADVKNSESDLRLEVTKQADKPFKPVNEAQATAAVKSLENAEYKVVSVEEKPSKSRPSAPFITSTMQQAASTRLGYGVKKTMMLAQRLYEGGYITYMRTDSTNLSKDAVEMCREYVTNEFGAKYLPADPINYSSKGNAQEAHEAIRPSSVSVLSGHVEGVDADAKKLYELIWRQFVACQMVPAEYDLTTLTVAANDFTLKAKGRVLRFDGWTKVQPAVRKKNEEDQSLPAVKQGEVLTLVELDPKQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFFAEKMGEIVTDRLVENFTDLMNFDFTAKMEGRLDDIAEGERVWTQVLDKFYADFSTQLNIAKGEPDEGGMRLNQMVETDIDCPTCGRKMGIRTASTGVFLGCTGYNLPPKERCTTTMNLVSGDEAVAADVEDVETETLMQMKRCPICETAMDSYLIDETRKLHVCGNNPACQGHVVEEGTFKIKGYDGPIIECDKCGADMELKSGRFGKYFGCNNDECKNTRKLLKNGEAAPPKEDPVHIPELECEKSEAYFVLRDGAAGIFLAANTFPKSRETRAPKVEELQRFRDRISPKFYYLADAPAKDPDGNLAVVRYSRKNKVQYVMTEVDGKATGWTAHYEGGKWVEEAKKKAAPKKKAAAKKAPAKSKAKAKPKKDDE
(1350) DNA topoisomerase 1 [Pectobacterium wasabiae WPP163]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSASKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWKANYEILPGKEKVVSELKTLAENADHIYLATDLDREGEAIAWHLREIIGGDDRRFSRVVFNEITKNAITQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHNGKPFKPVNKAQTHAAVSLLENARYIVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPEAAIAYSSKENSQEAHEAIRPSDVGVLADSLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEALSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALSPKERCKTTINLIPETEVLNVLEGDEAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIETGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMSCTGETCSNTRKILRNGDVAPPKEDPVPLPELSCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPEVDKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(1358) DNA topoisomerase 1 [Enterobacter aerogenes KCTC 2190]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERGALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDASTTTPGGDALPLQVTHKNDKPFRPVNRDETMAAVALLEKALYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGKKYLPENANQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGEFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPVVNQGDNLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKQVLDNFFGDFTSQLQTAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFFIDGKWTEAKK
(1391) DNA topoisomerase 1 [Haemophilus parasuis SH0165]
9
MGKSLVIVESPAKAKTINKYLGSDFVVKSSVGHIRDLPTSGAEKEEKTEKAKAVSTKGMTAEQKALVKSEKERTALVKRMGVDPYHDWNATYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGENERFSRVVFNEITKNAIKQAFEKPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEFWDILAKTSAKKGDLALELVQHKGKKFSVKNQKEAEQAVKSLQNSAFIVTEIDKKPTSSRAKAPFITSTLQQTASTRLGFSVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALTMARSYIEKQFGDRYLPEKPNFYASKEKAQEAHEAIRPSDVMVKMQDLSGMEKDAERLYDLIWRQFLACQMTPAEYDSTSLTVTAGDYELKTKGRVLRFDGWTKVLPIQGKTAEDQELPEVSLNETLKLNAVEPSQHFTKPPARYSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRVENRRFYAEKMGEIVTDRLNEAFSDLMNYDFTANMEDTLDQIASGNSNWKVELNRFFADFSEKLTTAELDELEGGMRSNNLVATDIHCPTCQRQMAIRTASTGVFLGCTGYALSPKERCKTTINLIPEAELLNVLDEDSETNALMKRKRCPKCDTAMDSYVIDPQRKIHICGNNPNCDGYVIEEGSFKIKGYDGPIVECDKCGSDMHLKLGRFGKYMGCTNCDNTRKILKNGEVAPPREEPVAFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRAPKVAELALYRDRLPEKLQYLADAPQQDPEGNEAIIRFSRKEKRQYVTSEKNGKATKWIVDYLDGKWVERHR
(1406) DNA topoisomerase 1 [Actinobacillus pleuropneumoniae serovar 5b str. L20]
9
MGKSLVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPKSGSESEKGEKAKPISTKGMTAEQKAKLKAEKDRAALVKRMGIDPYHDWKANYQILPDKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGDDERFSRVVFNEITRNAIQKAFEQPDHLNLDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWEILANTLTAKGKLPLDLTGYKGKKFSAKNQKQADEAVKSLQGSEFIVSEIDKKPTSSKASPPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALAMARGYIENQFGAEYLPAKPNFYSSKEGAQEAHEAIRPSDVNVKMADLKGMEKDAERLYDLIWRRFLACQMTPARYDSTSLTVTAGDYELKAKGRVLRFDGWTKALPVQGKTAEDQVLPEVALNEKLALEEVLPSQHFTKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLDESFSDLMNYDFTANMEETLDQIAEGNKNWKEALNNFFKDFSEQLTKAELDELEGGMKPNSLVPTEIDCPTCARKMAIRTASTGVFLGCTGYALPPKERCKTTMNLIPESELLNVLDEESEAKALLARKRCPKCDSAMDSYVIDPQRKLHICGNNPNCDGYVLEQGSFKIKGYDGPIVECDKCGADMHLKLGRFGKYMGCTACDNTRKILKNGEVAPPREEPTHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRAPKVAELAQYRDRLPEKLQYLADAPQQDPEGNEAIIRFSRKEKRQYVTSEKDGKATKWIVDYLDGKWLERKK
(1411) DNA topoisomerase 1 [Candidatus Moranella endobia PCIT]
9
MGTALVIVESPAKAKTINKYLGKGYVVKSSVGHIRDLPKKSPASKNKNNTCIPDQHTVLIKRMGIDPFHSWKARYEILPGKEKLVTELRALAEEADHVYLATDLDREGEAIAWHLREAIGGDEKRFRRVVFNEITRNAVTQAFENPVVLNMNRVNAQQARRFMDRIVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKSFMPAEYWELHVALQTSQAAQLMMKVTHQQEKPFKPAKQQQLQAAISILEHTDYIVSNRDDKITTSKPGSPFTTSTLQQAASLHLGYRVKKTMLLAQRLYEAGHITYMRTDSTHLSRNALNMARCYISAAFGHSYLPTQPKEYVSKNNSQEAHEAIRPSDVSALAEQLNNMEAEAQKLYQLIWRQFVACQMKPAQYNYTILTVNAGEFQLSAHGRQLMFDGWTKVMPTQHTEKDKRTLPTVKEGNNLTLNKILPSQHFTKPPARYSEASLVKELEKRGIGRPSTYVSIISTIQERGYVHADNRRFYAEKIGEIVTDRLEENFSELMSYDFTAKMEATLDQVATNQQDWKSVLDAFFSKFSQQLKNAEQNPVDGGMRLNQMIMTSINCLVCDRPMGIRTASTGVFLGCSGYQLPPKDRCKNTIHLIPESETLNRFTVGDEETNALRARRRCVKCRTAMDNYVIDSKRKIHVCGKNPLCDGYNIEQGEFIVVAYNGRVVECEKCGFNMQLKFGRFGKYIACTNNNCKNTRKILRNGDVAPPKEDPVLLPELPCYGHSDAYFVLREGAVGVFLAANTFPKYRETRKPLVAELARFRERLPVKLQYLADAPIEDDEGNSTLVRFSRKTKQQYISSEKDGKATGWTAFYVNGKWQVNRKSSGCGP
(1421) DNA topoisomerase 1 [Shewanella amazonensis SB2B]
9
MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSAAEGKASTKSAAEVRKMNPEEKAKYKAQKDKQALVARMGVDPEHGWQANYQVLPGKEKVVKELQSLASSADQIYLATDLDREGEAIAWHLQEVIGGDESRYKRVVFNEITKGAIQEAFSRPTDLNTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVEREAEIKAFVPEEFWDVHATLSTPAAAELVMEVSRYRNEAFEPVTQSEAMAAVNALEKAAFTVTDREDKATSSKPSAPFITSTLQQAASTRLGFGVKKTMMLAQRLYEAGHITYMRTDSTNLSQEALENVRAHIEKEFGSKYLPESPIRYGSKEGAQEAHEAIRPSNVKVESATLIDMERDAQRLYELIWRQFVACQMTPAVYDATRITAKAGDYELKASGRILKFDGWTRVQPALKKKNEEDNTLPDVQVGDMLSLKALDPKQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVKVENRRFYAEKMGEIVTERLVESFSELMNYDFTAGMEQTLDDVAKGDKDWKGVLDGFYSGFTAKLEKAEAEPDAGGMRPNQMVLTDIPCPTCGRQMGIRTGTTGVFLGCSGYALPPKERCKTTLNLTPGEEAISDSSEDAETDALRAMHRCGKCGMAMDSYLLDETRKLHVCGNNPECDGYEVEKGAFKLKGYEGPIIECDRCGSDMELKNGRFGKYFGCTNESCKNTRKLLKNGEAAPPKEDPIHLPELKCTKSDAYFVLRDGAAGIFLAASTFPRSRETRAPLVEELKKYREALWPKYQYLADAPVEDAEGNKALVKFSRKTKEQYVATEVNGKATGWSAHFKDGKWVESK
(1489) DNA topoisomerase 1 [Acinetobacter baumannii ATCC 17978]
9
MANTSRSASQSTASSASAAHKRALVIVESPAKAKTINKYLGSQYIVKSSVGHVRDLPTGGSKATEKKPAARTKLTEAEKEQKANQALINRMGVDPEHGWQAHYEVLPGKENVVAELKKLAKDADAIYLATDLDREGEAIAWHLREVIGGDDSRYHRVVFNEITKNAIQEAFKQPTRLDLNRVNAQQARRFLDRVVGFMVSPLLWEKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWQVFADTKAKKDDIRLEAVKQAGKTLKLKNKAETDALLDVLKGAEYKVAQREDKPTKVNPSAPYITSTLQQAASTRLGFSVKKTMMLAQRLYEAGFITYMRTDSTFLSDDAVSMVRAHIESQYGEKYLPAKPNRYGNKAGAQEAHEAIRPSNVALTGDQLAGVERDAQRLYDLIWRQFVACQMTPAEYLSSTLTVEAGNVELKAKGRTLVFDGFTKVRGANKSDDDIILPAIKVGEILKLEKLDPSQHFTKPPARFTEASLVKELEKRGIGRPSTYAAIISTIQERGYVKLENRRLFAEKMGEIVTDRLDESFNNLMNYAFTADLEGQLDRVATGERNWKELLDTFYGDFKKRLTNAQGEQGMRRNQPVEVPAVHCPECSRPMQIRTGTTGVFLGCSGYNLPPKERCKGTLNLTPVESLAALSDDDSAETADLMSKHRCPKCGTAMDSYVIDGGRKLHVCGNNPDCDGYELEEGEFKIKGYDGPTIPCDKCDGEMQLKTGRFGPYFACTSCDNTRKVLKNGQPAPPRVEPIKMEHLRSTKHDDYFVLRDGAAGLFLAASKFPKIRETRAPKVAELRSVADQLDPKYQFILQAPDVDPEGNPTIVKFSRKNQSQYVGSETPEGKQTKWSLIYQDGKWIEG
(1518) DNA topoisomerase 1 [Marinomonas posidonica IVIA-Po-181]
9
MGKSLVIVESPAKAKTINKYLGNDFVVKSSVGHIRDLPSGKTATSTPQERAKQAALTRKMSPEEKLEYKSRKSRKQLIARMGVDPEDNWHANYEVLPGKEKVVDELKRLAKNADTIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIQSAFETPSELDLNRVNAQQARRFLDRVVGFMVSPLLWAKVARGLSAGRVQSVAVRLIVEREQEIRAFVPEEFWELDAMLSTSSDDMIKFEAAKYQGKEYRPVNQLQSDEHVARLQMAKYLVQSREDKPTKSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSAEAVESLRQYILSSFGEAYLPADPIRYSSKEGAQEAHEAIRPSDVNVRVDDLLGMEKDAHRLYDLIRSQFMACQMTPAEYTSTTITVVAEEYEFKAKGRILRFDGYTRAMQTVVKKGEDNILPDVTQGEFLDLKELLPEQHFTKPVARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGDIVTDRLVGSFSSLMDFSFTAQMEERLDEIAEGDKDWIQTLNAFYRDFSNVLAKAESPDDGMMLNEPTPTDVECPTCSRPMQIRTASTGVFMSCSGYALPPKERCKATINLIRGDEAVAVDDEEGESKALINKHRCKICGSAMDSYLMDEHRKLHVCGNNPSCTGYEVEAGSFKIKGYDGPVIECDKCSSEMQLKTGRFGKYFGCTNEECKNTRKLLKSGEVAPPKMDPVPMPDLACQKVEDHYVLRDGATGLFLAASQFPRKRETRAPYVKELIPYMDQIDPKYHFFADAPVADSEGRSTLIRYSRKTKEQYIMTENEGKPTGWKAFYDGGKWVIEEGKKKK
(1519) DNA topoisomerase 1 [Kangiella koreensis DSM 16069]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSIGHIRDLPTGSQNKKPVDAKERARKAAATRKLSPEQKAKQKALKEKTALFARMGINPEHDWEARYEVLPGKEKVLNELKKFAKDADTIYLATDLDREGEAIAWHLRELLDGKETQFKRVVFNEITKKAIQQAFAKPGDLDMNYVNAQQARRFLDRVVGFMVSPLLWRKISRGLSAGRVQSVAVRLLVEREREIRAFIPEEYWDIHANTLTQSKDDLRLQVNKYQGKNFRPNSEQETNKALEVLKSSSYKVVTREDKPQKSKAPKPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTYLSTDAVDACRDYIKTNIGAEYLPKEANSYSSKEGAQEAHEAIRPSDVTKKVGHLSGMEKDAERLYDLIWRQFVACQMLPAEFDVTSLKVQAGDYELKARGRVMRFDGWTQVLPMQKKNAEDEELPNVKEGELLELKKLDPKQHFTKPPARFSEAALVKELEKRGIGRPSTYASIISTIQDRGYVRIENRRFYAQKIGEIVTDRLVESFSDLLDFSFTATMEKHLDDIASGRQNWKVTLDEFYDEFSQQLKKADEEEGEGGMRRNEAVETDILCDKCKKNHMAIRNASTGVFLGCMGYSLPPKERCKNTVNLIPGEEFIAADEEEEARYLHDKKRCTKCNSTMDDYLVDENTKLYICGNNPDCDGYEIEKGEFKIKGYDGPILECDKCGSEMQLKTGRFGKYFDCTNDDCKNTRKLLKSGQPAPPKADPIPMPELQCEKVDDHYVLRDGAAGIFLAASKFPRNRETRAPAVDELVTVKDKLDPKYKFLGEAPLKDPDGNRTFVKFSRKTGQQYVAGVKEDGKASGWTAFYENGKWVPQK
(1523) DNA topoisomerase 1 [Vibrio fischeri ES114]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPMGSTSTGKKAAASTKGLSVEEKARIKKERDKKNLINKMGIDPYNDWAANYQILPGKEKVVAELQKLAESADTVYLATDLDREGEAIAWHLREIIGGDDSRFKRVVFNEITKNAIQQAFETPGELSMPGVNAQQARRFLDRVVGFMASPLLWKKVARGLSAGRVQSVAVKVLVEREREINAFIPEEFWDIHADTLTADKENFRLQVAQRNGSAFKPLNQADTEAAVSILQNAEYEVCKREDRPTKSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEGGYITYMRTDSTNLSKEAVEALREFIGSEYGDSYLPAAPIVYGSKEGAQEAHEAIRPSSVEVKADDLQGMEADAHKLYNLIWNQFVACQMTPAQYDSTTLSVKADEFTLKAKGRILKFDGWTRVQRPMGKNEDQLLPAVQLGDKLKLEKLDPKQHFTKPPARFTEAALVKELEKKGIGRPSTYASIISTIQDRGYVRIDNRRFYAEKMGEIVTDRLNQSFDDLMDYDFTARMEGNLDRIAEGEKDWKDVLNTFFQDFTADIAKAELDESEGGMSPNNIVETDIKCPTCGRNMGIRTASTGVFLGCSGYALPPKERCKTTINLGSEEGIVNVLEEDVETAALRAKKRCPKCETAMDPYLIDQERKIHVCGNNPNCEGYVVEKGEFQLKGYDGPVVECDKCGSDMELKNGRFGKYMDCTSETCKNTRKILKNGEVAPPKEDPVHLPELVCEKSDAYFVLRDGASGLFLAASTFPKSRETRAPLVEELVRFKDRLSPKFLYLTEAPTHDPDGKPAVVRFSRKTKENYVRSEVDGKPTGWTGLYIDGKWAITDKRKKPKAEK
(1531) DNA topoisomerase 1 [Pectobacterium carotovorum subsp. carotovorum PC1]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSVSKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWQANYEILPGKEKVVSELKTLAENADHIYLATDLDREGEAIAWHLREIIGGEDERFSRVVFNEITKNAIKQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHSGKPFKPVNKEQTQAAVSLLENARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPESANLYSSKENSQEAHEAIRPSDVGVLADSLKDMETDAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEALSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALSPKERCKTTINLIPENEVLNVLEGDDAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIETGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTSETCSNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLAEAPVVDKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(1540) DNA topoisomerase 1 [Serratia plymuthica AS9]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDEKTALVNRMGVDPYHGWKADYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDEKRFSRVVFNEITKNAIQQAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKNDTALQMEVTHAHDKPFKPVNREQTHAALKLLEKARYTVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMEDGLDQVANNHAEWKAVLDEFFAEFSEQLETAEKDPEDGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNETCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADGEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1545) DNA topoisomerase 1 [Acinetobacter calcoaceticus PHEA-2]
9
MANTSRSASQSTASTAPAAHKRALVIVESPAKAKTINKYLGSQYIVKSSVGHVRDLPTGGSKSTEKKLAARTKLTEAEKEQKASQALVNRMGVDPEHGWEAHYEVLPGKENVVAELKKLAKDADAIYLATDLDREGEAIAWHLREVIGGDDSRYHRVVFNEITKNAIQEAFKQPTRLDLNRVNAQQARRFLDRVVGFMVSPLLWEKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWQVFADTQAKKDDIRLEAVKQAGKTLKLKNKAETDALLDVLKGAEYKVAQREDKPTKVNPSAPYITSTLQQAASTRLGFSVKKTMMLAQRLYEAGFITYMRTDSTFLSDDAVSMVRAHIENQFGEKYLPAKPNRYGNKAGAQEAHEAIRPSNVALTGDQLAGVERDAQRLYDLIWRQFVACQMTPAEYLSSTLTVEAANVELKAKGRTLVFDGFTRVRGANKSDDDIILPAIKVGEILKLEKLDPSQHFTKPPARFTEASLVKELEKRSIGRPSTYAAIISTIQERGYVKLENRRLFAEKMGEIVTDRLDESFNNLMNYAFTADLEGQLDKVATGERNWKELLDTFYGDFKKRLTNAQGEHGMRRNQPVEVPAVHCPECSRPMQIRTGTTGVFLGCSGYNLPPKERCKGTLNLTPVESLAALSDDDGAETADLMSKHRCAKCGTAMDSYVIDGGRKLHVCGNNPDCNGFELEEGEFKIKGYDGPTIPCDKCDGEMQLKTGRFGPYFACTSCDNTRKVLKSGQPAPPRVEPIKMEHLRSTKHDDYFVLRDGAAGLFLAASKFPKIRETRAPKVAELRSVAAQLDPKYQFILQAPDVDPEGNPTVVKFSRKNQSQYVGSETPEGKQTKWSLIYQNGKWVEG
(1551) DNA topoisomerase 1 [Ferrimonas balearica DSM 9799]
9
MGKSLVIVESPAKAKTINKYLGKDFVVKSSVGHIRDLPTSGGQAAEKAPPSKTPAEVRKMDPEAKAAYKRERDYQSLIGRMGIDPEHGWAANYQVLPGKEKVVKELQTLAEKADTVYLATDLDREGEAIAWHLQEVIGGDPERYRRVVFNEITKSAIQEAFSHPLHLDNAKVDAQQARRFLDRVVGFMVSPLLWKKLARGLSAGRVQSVAVRLVVEREREIRAFVPEEYWDLHADLSSASGDALRMQVARFNGEALKMVNQGDADKAVSALKEARYTISAREDKPSSSKPSAPFITSTLQQAASTRLGFGVKKTMTLAQRLYEAGHITYMRTDSTNLSKEAVESVRGYIGQEFGNQYLPSSPNLYGAKQGAQEAHEAIRPSDVNVKASTLSTMERDAQRLYELIWRQFVACQMVPAKYDSTTVTATAGSYELKAKGRIMVFDGWTRVQPPMGRKGDEDTMLPAVQVGDVLDLKALDPKQHFTKPVARFNEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFFAEKMGEIVTDRLVENFTDLLNYHFTAEMEQTLDKIAQGKLEWKAVLDQFYSDFTEKLTQAELAPEEGGMRANQMVMTDIACPTCGRPMGIRTATTGVFLGCSGYALPPKERCKTTINLTPGEEAEAITSDDQEAAALVTKRRCSKCESTMDSYLIDETRKLHVCGNNPVCDGYEVETGSFKIKGYDGPIIECDRCGSDMELKNGRFGKYFACTDSKETGCKNTRKLLKNGEVAPPKEDPVQLPELPCEKSDAHFVLRDGAAGLFLAASTFPKSRETRAPKVEELKRFKDRISPKFYYLAEAPQADPEGNPAVVKFSRKTKEQYVASEVDGKPTGWIARFENSRWVEEQTKKSKAKK
(1555) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Heidelberg str. SL476]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1556) DNA topoisomerase 1 [Shewanella sp. W3-18-1]
9
MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSTSEGNEKVKSAAEVKKMSPEEKAQYKKVKDQQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDPSRYQRVVFNEITKSAIQDAFSKPSTLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVPEEFWDVHAQLTTPAEESLRMEVVKHLDSAFEPINEQQALAAVQALSSASFKVISREDKATQSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALESVRDMIGKAFGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVHVEATDLTDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVKAGDYELKATGRTLRFDGWTRVQTVLKKKNEEDNTLPFVSQGDVLALKELQPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSERLVSSFADLMSYDFTASMEQTLDDVARGELDWKKVLDGFYADFTKQLEKAERDPEEGGMRLNQMVMTDIKCPTCGRPMGIRTGTTGVFLGCSGYELPPKERCKTTMNLTPGVEAISENSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPICEGYEVEEGQFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNEECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPICDDEGNKAAVKFSRKTKEQYVATEVDGKATGWSAHYINGKWVSESTAKKSKKA
(1563) DNA topoisomerase 1 [Psychromonas ingrahamii 37]
9
MSKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTPAKKEKEKAKRTQSALVARMGVDPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDLDREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFEHPTELNIDGVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKSDLRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQAASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEPVVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYELIWRQFLACQMLPALYDATTLVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTKPPARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSENFVELMSYDFTAQMERNLDAIAEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEPVIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCKTTINLVDGEEVVDLLSSEDLETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVECDKCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFILRDGASGIFLAANTFPRSRETRAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRYSRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVKAKK
(1587) DNA topoisomerase 1 [Rahnella aquatilis CIP 78.65 = ATCC 33071]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKTADSTEEKTKKKVKKDEKTALVNRMGVDPYHGWAAQYEILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKEPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLLAKKETALQMEVTHHLEKPFKPVNKEQTHAAVSLLEKARYTVVDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVEMVRGYIGENFGDKYLPKAPLQYSNKENSQEAHEAIRPSDVAVTSEQLKDMEADAQRLYQLIWRQFVACQMTPAQYDSTTLTVKAGDYSLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIEVGTDLELQQLLPTQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMEDGLDQVANNKAEWKAVLDEFFTEFSKQLETAEKDPEEGGMRPNQMVLTSIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGDEAETNALRAKRRCVKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELKRFKDRLPEKLSYLADAPVADPEGNKSMVRFSRKTKQQYVSSEKDGKATGWTAFFVDGKWVEGKK
(1611) DNA topoisomerase 1 [Vibrio cholerae O1 biovar El Tor str. N16961]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTAGQTATPTGKAAAASTKKASTTDKEQQKREKERAALIKKMGVDPYHGWQANYQILPGKEKVVAELQKLAKDADSVYLATDLDREGEAIAWHLREIIGGDEKRYKRVVFNEITKNAIQQAFKQPGELNMDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFVPEEFWDINADTLTADKQDFRLLVAQKDGLAFKPVNETEALAAVAALNKAQYEVCKREDKPTTSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSAEAVENLRGYITKHYGEAYLPSQPNVYGSKQNAQEAHEAIRPSDVTVTADDLEGMEADAHKLYALIWNQFVACQMTPAQYDSTTVSVKAAEYTLKAKGRILKFDGWTRVQRPLGKNEDQILPPVKVGDSLKLVSLDPKQHFTKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFFAEKMGEIVTDRLDENFDDLMNYDFTARMEEKLDQIAEGEVNWTAVLDEFFADFSRDLETAEQDESLGGMKPNHIVMTNILCPTCSRPMGIRTASTGVFLGCSGYGLPPKERCKTTINLGDEEGVINVLEEDVETAALRAKKRCPICETAMDAYLIDDKRKLHVCGNNPNCEGFIVEEGEFKVKGYEGPTVECDKCGSDMVLKNGRFGKYMGCTNDACKNTRKILKNGEVAPPKEEPVHFPELPCENSDAYFVLRDGASGLFFAASNFPKSRETRAPLVEELKRFAERLPEKYQYLTSAPAHDPDGLPAVVRFSRKEKEHYVRTETEGKPSGWMAVYQEGKWLVTDKRKNAK
(1613) DNA topoisomerase 1 [Aliivibrio salmonicida LFI1238]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPMGSTSTGKKTAAASTKGMSVEDKARIKKERDKKNLINKMGIDPYNDWAANYQILPGKEKVVAELQKLAENADTIYLATDLDREGEAIAWHLREIIGGDDSRYKRVVFNEITKNAIQQAFETPGELSMPGVNAQQARRFLDRVVGFMASPLLWKKVARGLSAGRVQSVAVKVLVEREREINAFIPEEFWDIHADTLTSGKENFRLQVAQRNGSVFKPLNQADTESAVSILEKAEYEVCKREDRPTKSKPSAPYITSTLQQAASTRLGYGVKKTMMLAQRLYEGGYITYMRTDSTNLSKEAVETLREFIGSEYGESYLPAAPIIYGSKEGAQEAHEAIRPSSVDVKVDDLQGMEADAHKLYNLIWNQFVSCQMTPAQYDSTTLSVKADEFTLKAKGRILKFDGWTRVQRPMGKNEDQLLPAVQLGDKLKLEQLDPKQHFTKPPARFTEAALVKELEKKGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLNQSFDDLMDYDFTARMEGNLDKIAEGSKDWKEVLNAFFQDFTDDIAKAELDESEGGMSPNNIVETDIKCPTCDRNMGIRTASTGVFLGCSGYALPPKERCKKTINLGNEEGIINVLEEDVETAALRAKKRCPKCETAMDPYLIDQDRKLHVCGNNPNCDGYIVEKGEFQLKGYDGPIVECDKCGSDMELKNGRFGKYMDCTSETCKNTRKILRNGDVAPPKEDPVHLPELECEKSDAYFVLRDGASGLFLAASTFPKSRETRAPLVEELVRFKDRLSPKFVYLTEAPTHDPDGKPAVIRFSRKTKENYVRTETDGKPSGWTALYLDGKWAVTDKRKKPKAEKES
(1632) DNA topoisomerase 1 [Haemophilus parainfluenzae T3T1]
9
MSKSLVIVESPAKAKTINKYLGSQYVVKSSVGHICDLPTAGSSTGEKAKPVSTKGLSAEEKNKIKAEKDRAALVKRMGIDPYHDWKANYQILPGKEKVVAELKSLAKKSDHVYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKKAIEKAFQHPAHINMDQVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLVVEREREIKAFQPEEFWEIEALTQTSKKEDLRLDVVQYKGKKFEPKNEKEAQSAVDFLNKSHYVVTDLETKPTGSKPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARSYIESHFGKDYLPAKPNFYSSKENAQEAHEAIRPSDVKMLADHLSGMDKDAVRLYDLIWRQFVACQMPAAQYDSTTVTVMAGDYELKAKGRILRFDGWTKVLPQLGKNPEDQILPAVSLNETLALKTVSPSQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRIENRRFYAEKMGEIVTDRLNQSFTDLMSYDFTANMENVLDQIASGEKNWKAELNQFFKDFSTQLSTAELDELEGGMKPNSLVLTDIDCPTCSRKMAIRTASTGVFLGCSGYALPPKERCKTTINLIPETELLNVLDEASETKALMDRKRCPICGTAMDSYIIDPHRKLHICGNNPNCDGYLVEQGQFKIKGYDGPIVECDKCGSDMHLKLGRFGKYMGCTNCDNTRKILKNGEVAPPKEEPVHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRPAKVAELALYRDRLPEKLRYLADAPQKDPEGNEAIIRFSRKEKHQYVTSEKNGKATKWIVDYIDGKWVERKK
(1636) DNA topoisomerase 1 [Teredinibacter turnerae T7901]
9
MGKSLVIVESPAKAKTINKYLGNQYIVKSSVGHIRDLPTSGSAKTTTDPKARAKQAALTRKMSAEEKEVYKQNKAREQLINRMGIDPDNDWQAHYEILPGKEKVVAELRKLADQADHIFLATDLDREGEAIAWHLQESIGGDPTRYRRVVFNEITKNAIQEAFKSPGMLDINRVNAQQARRFLDRVVGYMVSPLLWEKIARGLSAGRVQSVAVRLVSERESEIRAFIPEEYWEVKAQLDTSKGERAKYEVKRFKDEAFKPVNEAQAMAAKSALEGAAYKVTEREDKPTKSNPSAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTNLSKEAVENCRTFIQQEYGDRYLPKAPNVYSSKEGAQEAHEAHEAIRPSDVTTRPNQLSGMERDAERLYNLIWQQFVACQMTSAEFTSSSLKVSAGDYELRARGRVIRFDGFMKVMPPVSRKEEDTLLPDVKVGDMLDLHEILASQHFTKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVHVENKRFYANKMGDIVTERLIESFSDLMDYGFTANMEAALDTVAEGDKDWLDLLNEFYADFTVKLEMAQNSAAGMRRNEPVETDIDCGNCGRKMQIRTGSTGVFLGCSGYALPPKERCKNTMNLVSGDEAVNIDEDEDAESRQLRQKRRCKICNTAMDSYLLDEQRKLHICGRNPDCDGYEVEQGVFKIKGYDGPLIECDKCGSDMQLKSGRFGKYFGCTNDECKNTRKLLRNGEAAPPKMDPVDMPELACEKVEDHYVLRDGASGLFLAASQFPKNRETRAPYIKELLPHKDEIDPKYAFLFKAPTQDDNGNDALVRYSRKTKEQYVQTEVDGKATGWKAFYDGGKWQVSGSAKPTKAAPKAKATRKKKS
(1639) DNA topoisomerase 1 [Serratia sp. AS12]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDEKTALVNRMGVDPYHGWKADYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDEKRFSRVVFNEITKNAIQQAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKNDTALQMEVTHAHDKPFKPVNREQTHAALKLLEKARYTVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMEDGLDQVANNHAEWKAVLDEFFAEFSEQLETAEKDPEDGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNETCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADGEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1656) DNA topoisomerase 1 [Proteus mirabilis HI4320]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPKSGSGSQKSENSSATKGVKKVKKDEKSALVSRMGVDPYNGWHANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGEDDRFSRVVFNEITKNAITQAFQTPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLLVEREREIKAFVPEEYWQLHASLLTPDEQPLRMEVTHYQDNAFKPVSSEETQVAVKALQNATFIVKNREDRPTSSKPSAPLITSTLQQAASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDAIQMARDYIHDKFGAKYLPKEPNVYSSKENSQEAHEAIRPSDINVTAESLKDMDSDAKRLYQLIWDQFVACQMTPAKYDSTTLTVVSGDYKLRAKGRTLRFAGWTKVMPAMRSKDEDKTLPAVDVGAQLALAELSPTQHFTKPPARFSEATLVKELEKRGIGRPSTYASIISTIQDRGYVKVENRRFYAEKMGEIVTDRLEENFSDLMNYDFTAQMEDHLDHVANNQENWKAVLDAFFTDFSQQLEVAEKDPEEGGMRPNPMVITSIECPTCSRHMGIRTATTGVFLGCSGYALPPKERCKQTINLIPEDELLNILEGDDAETNALRARRRCPKCGTAMDSYLIDTHRKLHVCGNNPACDGYEVEEGEFRLKGYEGPVIECDKCGAEMHLKMGRFGKYMGCTNEECKNTRKILKSGEIAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPKVAELVRFKDRLSEKMRYLAQAPVTDPEGNPTIVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEKSK
(1695) DNA topoisomerase 1 [Vibrio anguillarum 775]
9
MGKSLVIVESPAKAKTINKYLGKDFIVKSSVGHVRDLPTAGQSTAKKATSSSSSKNLSAEEKARLKSEKDRSSLIKKMGIDPYHGWEANYQILPGKEKVVAELQKLAKDADCIYLATDLDREGEAIAWHLREIIGGDEQRYKRVVFNEITKNAIQQAFQTPGELNIDGVNAQQARRFMDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREINAFVPEEFWDIHADTKTQDKTDFRLLVAQKNDVAFKPVNEAEAKSAVSILEKASYEVCKREDRPTSSKPSAPFITSTLQQAASTRLGYGVKKTMMLAQRLYEAGYITYMRTDSTNLSAEAVEAVRSYIGSEFGQAYLPENPLAYGSKQGAQEAHEAIRPSSVDVKADDLQGMEADAHKLYALIWNQFVACQMTPAQYDSTTVSVKAAEFTLKAKGRILKFDGWTRVQRPMGKNEDQILPPVKVGETLLLQTLDPKQHFTKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQRRFYAEKMGEIVTDRLDDSFNDLMNYDFTARMEEKLDQIAAGSANWKGVLDDFFKDFTADLETAELDEEQGGMKPNHIVMTDIQCPTCSRPMGIRTASTGVFLGCSGYALPPKERCKTTINLGDEEGVINVLEEDVETAALRAKKRCPICETAMDAYLIDDTRKMHVCGNNPNCEGYVVEFGEFKVKGYDGPVVECDKCGSNMVLKNGRFGKYMDCTSDDCKNTRKILRSGEVAPPKEDPIHFPELPCENSDAYFVLRDGASGLFLAASNFPKSRETRAPLVEELARFKERLAPKYQYLADAPAHDPDGVAAVVRFSRKSKEHYVRTEIDGKPSGWTALYDNGRWEITDKRKNAKK
(1696) DNA topoisomerase 1 [Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSASQKSSSSSTDKSKKKVKKDEKAALVSRMGVDPYRGWEANYQILPGKEKVVAELKSLAEKADHVYLATDLDREGEAIAWHLREVIGGDSDRFSRVVFNEITKNAIKQAFDKPGELNIDRINAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWQLHADLLAKGEISLHMEVTHKRGKPFKPVNSEQTQAAVSLLEKARYKVVDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALDMVRGYISDNFGDKYLPKTANTYSSKENSQEAHEAIRPSSVDVMAEQLKDMDADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFELRAKGRTLRFDGWTKVMPALRKGDEDHTLPVVEVGTELDLQQLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYSEKMGEIVTDRLEENFNELMSYDFTARMEDQLDQVASNKAEWKGVLDEFFTDFSEQLEVANKDPEDGGMRPNPMVITSIACPTCDRPMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNILEGDEAETNALRARRRCKKCGTAMDSYLIDNQRKLHVCGNNPACDSYEVEEGEFRIKGYDGPVIECDKCSSEMHLKMGRFGKYMGCTNETCKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADAEGNKTVIRFSRKTKQQYAASEKNGKATGWSVFYVDGKWIEKDKK
(1727) DNA topoisomerase 1 [Shigella flexneri]
9
MGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1729) DNA topoisomerase 1 [Aeromonas veronii B565]
9
MGKSLVIVESPAKAKTINKYLGKDYVVKSSVGHVRDLPTSGSASTEPKKPVIRGIKLSESEKAAKDRKALFARMGINPTAGWQANYQILPGKEKVVSELQSLAEKADTIYLATDLDREGEAIAWHLREIIGGDDSRYKRVVFNEITKSAIKEAFAQPSELNIDRVNAQQARRFLDRVVGYMVSPLLWKKLARGLSAGRVQSVAVRLIVDKEREIKAFVPVEFWDLNADLLTGDKSDLRMEVVSRNGADFKPVTQAETFAAVAALEGVDYKVVNREDKPTGSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGYITYMRTDSTNLSKEAVEAVREYIGEQYGAAYLPAEPNLYGAKANAQEAHEAIRPSNVQVTAEMLEGMEPDAMRLYDLIWRQFVACQMTPAQYDSSTLTVKAGEFELKARGRTLRFAGWTKALPPMGRKGEDSQLPAVTVGEVLKLIKLDPRQHFTKPPARFTEAALVRELEKRGIGRPSTYASIISTIVDRGYVRVESRRFFAEKMGEIVTDRLVENFVELMNYEFTAKMEDKLDGIADGSLEWKKVLDAFYAEFTQELEKADKAPEEGGMRANQMVMTDIDCPDCGRKMGIRTATTGVFLGCSGYALPPKERCKKTINLVSADEFVSATDGEEAETEALRAKHRCGVCGTAMDAYIIDDSRKLHVCGRNPDCDGYEIEKGQFKLKGYEGPSIECDRCGAEMQLKNGRFGKYMGCTNETCKNTRKILKNGDIAPPKEDPVPLPELKCTQSDAHFVLRDGAAGLFLAASNFPKSRETRAPLVEELKRFKDRISAKHKYLAGAPLTDPDGNPAIVRFSRKTKEQYVMSEVNGKATGWTAHYDNGTWQESLPKAKKA
(1732) DNA topoisomerase 1 [Pseudomonas syringae pv. syringae B728a]
9
MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSASAAKDPAAKRGKAAAGEGPVLTPKEKAQRQLVSRMGVDPEHGWKAKYEILPGKEKVIEELRKLAKDADIIYLATDLDREGEAIAWHLREAIGGDDSRYKRVVFNEITKKAIQEAFSKPGELDIARVNAQQARRFLDRVVGYMVSPLLWQKVARGLSAGRVQSVAVKLVVEREREIRAFNPEEYWEIHADLGTAKGANVRFEVARENGEAFKPLNETQAMAALEKLKASSYSIVKREDKPTSSKPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADAVSMARDYIGTEFGKKYLPESPNVYSSKEGAQEAHEAIRPSDVNTHPSKLTGMERDAERLYELIWRQFVACQMLPAQYLSTTVTVAASDFELRAKGRILKFDGYTRALPQMAKPGDDDVLPDMAQGETLKLNKLDPSQHFTKPPARYSEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVALHNRRFYSEKMGDIVTGRLSESFSNLMDYGFTAGMEENLDDVAQGERDWKNVLDEFYGDFRKKLEVAEAADGGMRANQPVMTDIPCKVCGRPMQIRTASTGVFLGCSGYSLPPKERCKATVNLTPGDEIADDDEGESESRVLRGKHRCPICSTAMDAYLLDEKHKLHICGNNPDCTGYEIEEGTYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPDCKNTRKLLKSGDAAPPKMDPVKMPELKCDKVDDTYILRDGASGLFLAASQFPKNRETRAPLVIEIAPHKDEIDPKYHFLCEAPKKDPDGRPAVIRYSRKTKEQYVQTEVEGKPTGWRAFYDGSAWKVEDKR
(1735) DNA topoisomerase 1 [Photorhabdus luminescens subsp. laumondii TTO1]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSASQKSSSSSTDKSKKKVKKDEKAVLVNRMGVDPYRGWEANYQILPGKEKVVAELKSLAEKVDHVYLATDLDREGEAIAWHLREVIGGDGDRFSRVVFNEITKNAIKQAFDNPGELNIHRINAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPVEYWQLHADLLAKGEISLHMEVTHQQGKPFKPVNSEQTQAAVSLLEKARYKVLDREDRPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALDMVRDYISDNFGDKYLPEAANTYSSKENSQEAHEAIRPSSVDIVAEQLKDMDVDAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFELRAKGRTLRFDGWTKVMPVLRKGDEDHTLPVVEIGTELDLQQLIPSQHFTKPPARYSEASLVKELEKRSIGRPSTYASIISTIQERGYVRVESRRFYSEKMGEIVTDRLEENFNELMSYDFTARMEDQLDQVASNKVEWKGVLDEFFTDFSEQLDVANKEPEEGGMRPNPMVITSIECPTCQRSMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNVLEGDEAETNALRARRRCKKCGTAMDSYLIDSQRKLHVCGNNPACDSYEVEEGEFRIKGYDGPVIECDKCGAEMHLKMGRFGKYMGCTNETCKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKERLPEKLRYLADAPVVDAEGNKTVIRFSRKTKQQYASSEKNGKATGWSVFYVDGKWVEKDKK
(1742) DNA topoisomerase 1 [Yersinia enterocolitica subsp. enterocolitica 8081]
9
MGKALVIVESPAKAKTINKYLGNNYVVKSSVGHIRDLPTSGSASKKSANSTEDKAKKADKPKTKVKKDEKVALVNRMGVDPYHGWKAQYEILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKGEVPIQMEVTHAHNKPFKPVNREQTHAALKLLENARYKVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPSAPNQYSSKENSQEAHEAIRPSDVNVMAEQLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSELDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKAVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPEAEILNILEGDDAETNALRAKRRCQKCGTAMDSYLIDNQRKLHVCGNNPTCDGYEIEEGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVTDNEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEAKK
(1760) DNA topoisomerase 1 [Cronobacter turicensis z3032]
9
MGKALVIVESPAKAKTINKYLGKDFVVKSSVGHIRDLPTSGSAPKKSAESAPTKPAKKVKKDERGALVNRMGVDPWHNWEAQYEVLPGKEKVVSELKSLAEKADHIYLATDLDREGEAIAWHLREVIGGDETRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDALLSTPKSDQLSVQVTHHKDKPFRPVNRQDTEAAVALLKAASYQIVEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVSMVRNYIGEEFGKKYLPENPNQYASKENSQEAHEAIRPSDVSVLAESLKDMENDAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFRLKARGRILRFDGWTRVMPALRKGDEDRTLPAVNQGDKLSLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFPELMNFDFTAQMEDSLDQVANHEAEWRGVLDTFFDDFSRQLDTAEKDPEEGGMRPNQMVLTSIDCPTCGRPMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEVEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFRDRLPEKLLYLADAPAQDPEGNPAVVRFSRKTKQQYVASEKDGKATGWSAFYVDGKWAEGKK
(1770) DNA topoisomerase 1 [Erwinia pyrifoliae Ep1/96]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKTTKKVKKDEKTALVNRMGVDPFHGWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRQAFDRPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVDREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINREQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYVEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMDADAQKLYQLIWRQFVACQMVPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKAVLDQFFGDFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALSPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYDIEQGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAKDADGNKAVVRFSRKTKQQYVSTEKDGKASGWSAFYVDGKWEVTKK
(1777) DNA topoisomerase 1 [Citrobacter rodentium ICC168]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGDALPLQVTHQNDKPFRPVNREQTQAAVSLLEKARYTVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDSFGKKYLPDSPNQYASKENSQEAHEAIRPSDVTVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLVELIPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHEAEWKAVLDNFFSDFTQQLDKAEQDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVAAEKDGKATGWSAFYVDGKWVEGKK
(1778) DNA topoisomerase 1 [Dickeya zeae Ech1591]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSGSASKKSAEANGEKAKKAVKKDERTALVNRMGVDPYRGWQAHYEILPGKEKVVSELKMLAQNADHVYLATDLDREGEAIAWHLREIIGGDEKRFSRVVFNEITKNAIRQAFENPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELHADLLANAETALQMQVTHHHGKPFRPVNQAQTQAAVSLLEKASYVVNEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMARDYIQGEFGKRYLPDAPNLYTSKENSQEAHEAIRPSDVSVLADQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLVVSAADYQLRAKGRTLRFDGWTKVMPALRKSDEDRTLPAVEIGQSLSLEKLSPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMENSLDLVANSQAEWKAVLDEFFAEFSQQLETAEQEPDEGGMKPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLIPEAEVLNVLEGDEAETNALRARRRCSKCGTAMDSYLIDNQRKLHVCGNNPSCDGYEIEQGEFRLKGYDGPVVECEKCGSEMHLKMGRFGKYMACTSDSCGNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFRDRLPEKLRYLADAPVTDPQGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYVDNKWVETAR
(1804) DNA topoisomerase 1 [Oceanimonas sp. GK1]
9
MSKSLVIVESPAKAKTINKYLGRNYVVKSSVGHVRDLPTAGSAGGKKPAARKTDTKQLSPEEKARLKKEKEHKALIARMGVDPEHGWKADYQVLPGKEKVVSELQALAEKADTVYLATDLDREGEAIAWHLKELIGGDDSRFKRVVFNEITKSAIQDAFSQPAELNLNRVNAQQARRFLDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEKEREIKAFVPEEYWDIQAALSNEQQLALSMMVAKYQGKEFRPTNEADAMAAVTALRASSFEVASREDKPTQSKPPAPFITSTLQQAASTRLSFGVKRTMMLAQRLYEAGYITYMRTDSTNLSQEAVASVRDFIEQHHGSAYLPESANVYGAKANAQEAHEAIRPSDVTLSADQLDGMEADAKRLYDLIWRQFVACQMTPAQYDSSTITVRAGDYELKARGRILRFAGWTRVLSPQSRKGEDTELPAVQAGETLSLNELTPKQHFTKPPARFTEAALVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVADRLQESFAELMNYDFTAQMESKLDEIAGGKLDWTQVLDAFYAEFSDELEKAEQPAEEGGMRANQMVLTDIDCPACGRKMGIRTATTGVFLGCSGYALPPKERCKQTINLIPGDDFVLANDEEAETDALRAKHRCSKCGTAMDAYLIDDKRKLHVCGQNPDCDGYELEQGQFKLKGYEGPVIDCDRCGAEMQLKSGRFGKYMACTSEACKNTRKILKNGEVAPPKEDPVHLPELPCSQSDAYFVLRDGAAGLFMAASNFPKSRETRAPLVEELVRFKDRLPAKFRYLAEAPTEDPDGNKAVVRFSRKNKEQYVMTEVNKKATGWTAHYVDGKWQQHQKGKK
(1805) DNA topoisomerase 1 [Shewanella violacea DSS12]
9
MGKSLVIVESPAKAKTINKYLGKDYIVKSSVGHVRDLPTSSSPDSKVATKTPAEVRKMAPEEKAIYKSKKAKQALVARMGVDPDNGWKAKYQILPGKEKVVKELQALAEKADKIYLATDLDREGEAIAWHLQEIIGGDESRYQRVVFNEITKTAIQEAFSKPAHLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVATRLVVEREGEIKAFVPEEFWDIHAQLNTQANDLLKMQVVKFQGKAFNPVNEQQTLEAVSALSQSSFVVAARDDRATQSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDNVREMIAKEFGDKYLPDEPIRYGSKDGAQEAHEAIRPSDVKVHAALMSDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVKSGEYELKATGRTLRFDGWTRVQTAIKKKNEEESTLPHIEQGDKLDLKELDPKQHFTKPPARYGEASLVKELEKRGIGRPSTYATIISTIQDRGYVRVENRRFYAEKMGEIVSESLVGSFKELMSYDFTAGMEQTLDDVAKGELKWKKVLDGFYKDLTKQIEQAELPPEEGGMRPNEMVPTDNIKCPTCERPMGIRTGTTGVFLGCSGYALPPKERCKTTMNLTPGEEAVSENSEDVETDALRAKHRCDICGTAMDSYLIDETRKLHVCGNNPICVGHEVELGQFKIKGYEGPIIECDRCSNDMELKNGRFGKYFGCTNSECKNTRKLLKSGEAAPPKEDPIHLPDVKCTKSDGYFVLRDGAAGIFMAASTFPKSRETRAPLVEELVKYRELLWPKYAYLADAPVKDDDGNKASVRFSRKTKEQYVATDVDGKATGWTSKFIDGKWVTEAKKKAKPKAKAATTTKAKAKPKAKAKPKKAEKTED
(1810) DNA topoisomerase 1 [Shigella boydii Sb227]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1819) DNA topoisomerase 1 [Xenorhabdus bovienii SS-2004]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGAASQKSSNSSTDKNKKKKDEKTALVNRMGVDPYHGWEADYQILPGKEKVVAELKMLAEKADHIYLATDLDREGEAIAWHLREVIGGGEARFSRVVFNEITKNAITQAFDNPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWQLHADLMAKGDIDLHMEVTHEGGKPFKPINAQQTQAAVSLLEKARYKVLDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALDMVRGYINDQFGDKYLPKTANIYSNKENSQEAHEAIRPSSVDVMAEELKDMEADAQKLYQLIWRQFIACQMMPAKYDSTTLTIQAGNFELRAKGRTLRFDGWTKVMPALRKGDEDHTLPVVEVGTELDLKQLSPSQHFTKPSARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRGENRRFYAEKMGEIVNDRLEENFNELMSYDFTARMEDQLDHVANNEANWKGVLDEFFTNFSEQLDVASKDPDEGGMRPNPMVSTSIDCPTCSRPMGIRTATTGVFLGCSGYTLSPKERCKQTINLIPENEILNILEGDEAETNALRARHRCKECGTAMDSYLIDNQRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGSEMHLKMGRFGKYMGCTSEECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAASTFPKSRETRAPLVEELVKFKDRLPEKLCYLAKAPVADPEGHKTVVRFSRKTKQQYVSSEKNGKATGWAAFFVDGAWVVKEK
(1866) DNA topoisomerase 1 [Haemophilus influenzae R2846]
9
MSKSLVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGNNDRFSRVVFNEITKNAIKQAFEKPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWEVAVLTNNQNKQAIRLDVTDYKGKKFDPKNQKEAQSAVDFLNVSDYVVTDLETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARSYIENHFGAQYLPEKPNFYSSKENAQEAHEAIRPSDIRALPESLEGMEKDAVRLYDLIWRQFLACQMPPAQYDSSTLTVSAGDYTLKAKGRILRFDGWTKVLPQIGKNPEDQELPSVTVSEKLALKEVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNESFGELMNYDFTANMEDTLDKIASGSVNWKTELNQFFKDFSSQLSKAELDELEGGMRPNNLVETDIKCPTCDRNMAIRTASTGVFLGCTGYALPPKERCKTTINLIPEAELLNVLDESSETKALMDRKRCTKCGTAMDSYVIDAHRKIHICGNNPNCDGYLIEEGSFKIKGYDGPVVECDKCGADMHLKLGRFGKYMGCTNCDNTRKILKNGEVAPPKEEPVHFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRPVKIAELVQYRERLPEKLAYLADAPQKDPEENEAIVRFSRKEKKQYVTSEKEGKATKWIVDFTNGKWVERKK
(1869) DNA topoisomerase 1 [Shigella sonnei Ss046]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTIGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKIGEIVTDRLEENFRELMNYDFTAQMENSLDLVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1874) DNA topoisomerase 1 [Shewanella sediminis HAW-EB3]
9
MGKSLVIVESPAKAKTINKYLGKDYIVKSSVGHIRDLPTSSSTEAKVATKTPAEVRKMAPEEKAIYKSIKAKQALVSRMGIDPDKGWKANYQTLPGKEKVVKELQKLAESADQIFLATDLDREGEAIAWHLQEVIGGDASRYQRVVFNEITKSAIQDAFSKPSTLDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVATRLVVEKESEIKAFVPEEFWDIHAQLETLNNAALKMQVVKFQDKAFNPVTESQAQTATSALSQSSFVVAARDDRATSSKPSAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDGVREMIAKEFGDKYLPEAPIRYGSKGGAQEAHEAIRPSDVSVQAASMKDMERDAQRLYELIWRQFVSCQMTPAKYDATRLTVKAGEYELKATGRTLRFDGWTRVQTVVKKKNEEDNTLPVVAQGDKLNLQELMPKQHFTKPPARYGEASLVKELEKRGIGRPSTYATIISTIQDRGYVKVENRRFYAEKMGEIVSESLVGSFKELMSYDFTASMEQTLDDVAQGELKWKKVLDGFYKDLTKQIEQAELAPEEGGMRPNEMVLTDNIKCPTCDRPMGIRTGTTGVFLGCSGYALPPKERCKTTMNLTPGEEAVSENSEDAETDALRAKHRCDVCGTAMDSYLIDEKRKLHVCGNNPICGGYEVEQGQFKIKGYEGPIIECDRCGNDMELKNGRFGKYFGCTNDDCKNTRKLLKSGEAAPPKEDPIHLPELKCTKSDGYFVLRDGAAGIFMAASTFPKSRETRAPLVEELVKYRELLWPKYAYLADAPVTDDDGNKATVRFSRKTKEQYVATDVDGKASGWASKFIDGKWVSESKKKAKPKAKAKPKEKK
Taxa distribution
Family tree
9