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Taxon : Sulfolobaceae
Informations
Name
Sulfolobaceae
Rank
family
# topoisomerases
17
Lineage and sub-taxa
Lineage
Archaea
>
Crenarchaeota
>
Thermoprotei
>
Sulfolobales
>
Sulfolobaceae
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(402) Reverse gyrase 1 [Sulfolobus tokodaii str. 7]
6
MLKVYYTFGCPNCGGPIDDEHLLAGVPCSKCLPGRVENLDYRVIYDLLVKNSTLKGYAEYFYDNETFEEIVRIFKRVIGNEPWNLQKYWIKRLAKSESFSLSAPTGLGKTTTLLVYSLFFSNTTLYVVPTNSLKDQICERLRNMGAKVSCNDVKEEYINVATFNRILRHYDNYVSLQPKLVIVDDSDMILKSGKTTEVMAKILGISEEIFQYAISLIRLKRILKFNEDDKELKNKIVELEYKIGSWKPFVQFLVASATLRPKGIKQQALRTLIGFEPSTIQTYLRNIADLYYQGVDIEAILDKISDNGGLLLVSKEYGREKMLELKEIIEKRGYSTGLAISGRKFLNKFTEGKIDYLIGSASYYGVAVRGLDEPKRLKYVIFYGIPKIRLNLTDALNNPSLIVKIGELLNIDVKDIRRKLLFLSPPEFQILRYSLMKDEELSGKLKDIKVNLINIKEKIWDVLKSDNIKKLKADTFLVTENNGKYYVYIPDTVTYIQASGRSSRIISNGLTFGISIVLVDNIDLLDILSQKLKKIIPNFMFKNINEVDIRELKSLAVSSREVSTSQKKKINIKTILLIVESPTKAKTIARLFGRPSRREVHGIPVYETIILVNDEILITNIIATKGHITDLTTENIGYYGVEVGNNEFNAYYSPIYKCYNCGKTFTIKSNTCPYCGSVFISSSEKVVSALRKLSTEVDEIYIASDPDQEGEKIAYDVAMLISPYNKNIYRIKYHEITRNGILNAILNKGKINMNLVKSQIVRRIEDRWIGFELSLALKSMFYERNHGSGRVQGPVLSWIVERTKEYKKNYGWILYIKLGDYAIKKFFRIKEEANKFIEKLNIKINLISERKEIQNPLPPFTTDSLLMDAYDKLGIGSQIVMKIAQDLFESGLITYHRTDSTHVSALGISIAKEYLESKNLNDSFSGRSWGNEGTHEAIRPTSSMDTESLIKDIEDNPNKYFIKFTKYHLRIYDLIFRRFIASQMKPAEVTYSKFEIFINGEKLEVELPTKISGGFSIIYPLKTYVVSEKYSTYLTKGSIIPLFTYAEIIKNMKEKEIGRPSTYAKTISALIRHGYVVESKRKALLIATNKGIKAYEFLSSCCSDLISENRTKLLLQKIDKIANGDVNVDYVLEDLHKEITQISGKLVNSLKLDTNV
(951) DNA topoisomerase [Sulfolobus tokodaii str. 7]
3
MNCYPKNYILVIAEKSKAAKKIAEALSDKPTTCKKYSVSYWVVNYKGKVNVVAPAAGHLFNLYGDSSFPIFSMDWKPLWEIDDSAKYTKKYYNLLKDLSKYAIEYINACDYDIEGSVIGYMIIKHFGDLKKAKRMKFSALTKQDIQKAYSNLSPLDYNMINAGIARHKVDWIWGINVSRALMLAVSSVTKKRVTLSAGRVQSPTLIHVVENEIARELYIPLPVYRVRVKIKIGNETFSLSLNRTFEYKEEAQEFANKIKKSRAVVDEVRIEEKPLTRPSPFNLGDLQAEAGRILGYSPYYVERLAEELYLDGLISYPRTNSQKIPPSVDIKSIVNGLEANFKNLVGLVRNITKGEYIVRQGSKDDPAHPAIYPTGNRITEKLGIKQYKLFELITRRFLASISRDAIMITQKIIIRFKDVDISDEITRQKIKFKGWLLLYPYHSVKDEELLDVKEGEEVKIESVSVKMDLAKPDVKRYNKVQLLKWMETSNLGTEATRGKIIETLFNRKYLSQKRGTIYPTSLGIVIVEVLKDYFKDLTSIELTSKMEEKLNEILDGKETVEGVVAETINTLRIYLDNYNKYKDQIGIKLAKILGLMKYKKCKFCDLEAEYDNLCKYHYNAYMKLKETLKVWKERTKLEDKDILKKIYSSKTTGKYIKDMISEMM
(1183) DNA topoisomerase [Metallosphaera sedula DSM 5348]
7
MKLVITEKPSVALDIARALGKPTRRQGYLEVGEYLVTWTYGHLLEIGEIAPKRWNLKDLPIFPEKFEYDLIKGKESQFKVVRKLLEGADAVINCGDAGREGELIVRELLEFTGYRGKVLRLWTSEALTRDVVLRELRRLRPSSEFDSLYYSALARQNGDWIVGINLTRLVTLKAGGGEVWSVGRVQTPTLAMIVKRDREIEAFKPEIYYVVLAGFEGEMKGVMLRNGEEARLAREEAEQVVNALKSVRSGRVEKVDVERREERPPLLHSLTSLQREANTLYGLSAKRTLDVAQSLYEEWKLISYPRTDARYLGEGNRDLVKDVLRKLGRGELVPRVDRVGKRVFDSSKLTDHHAIIPLDRPPENLPAIHRKVYDLVYRKFVGAFMDDYVYELQRVFIRLDGELFLVEGKRNLQLGWMELYPHEDNPLKIPSGEVRKEWVKAEERQTKPPARFTEASLLREMERLGLGTPATRAGIIETLLERGYVERRGKSLYSTDKGRELVDKLGDSKVVSPDMTAEWERQLEEIYVKRLGEKGYQEFMEGIRRFTREEVERLMKREFKVERRATPEMLRLARAVSRDLGVKLEGTGMEEVKRFLDENLPKMRITCKCGGEVVGFSRGWKCRKCGTVVWREIAGKKITFRQAKSLFQGKELKMKGFRSRTGKRFSATVYLEDGKVKFKFE
(1748) Reverse gyrase [Metallosphaera sedula DSM 5348]
6
MITSVFHSSCPNCQGPLEDYRALAGLPCTSCMPGSVDSFKDLPQEEKIKVVYNILVNNGKLGKYWELYYTTEMYNEIINYFKQVTGNEPWSLQRLWLRRLGERENFSLSAPTGMGKTTTLITYSTYLSKGVLYIVPTKSLQEQICSKIGAISSVSCGKVDPNTISVLTVSYVNKNYDHMKDYRPNFIAVDDADAIIKSGKTTDKLVELMGIPKDVYEDAMRLVRLRRMLYLKDNKDEIVEKIALLERKIQSFTGIIAQLVVASATLRPKGVKQKALRHISGFDISTAQTYARNIVDSFTFSSLEEVVQKLGPGGLILVSREYGKEKMKEIKESLTSLNFRVELAVSGRKFLQDFSDGKTDILVGSASYYGVAVRGIDEPKRLKYVLFYGVPKSRTRAEESVKNPFTLLRVSRLLGIQVPEEEILGLSPAEAQAIKIAMITGQSLEGRLGALLEKMKVLVEEAQEALRKVDGTITGETFQISRKGREVFIEYPDIITYLQGSGRSSRLLNGGLTQGLSVILVDDQVIFELFKRKMNFLIPGFAPVNFEALELDRVKEEIERTRREGGNKVEIKTGLLVVESPTKAKTISRLFGFPARRSVGGVPVYETVIVEGNRVYILDVMATKGHVTDLTLEEKGYYGVEIKGDKISPLYSHIYRCASCKRSVSKEVETCPYCGSNLISSSLSTINAMRKLALEVDQIFIATDPDTEGEKIAYDVAVNVSPYNPNIMRIRYHEVTRSGIVEALRSGSTLDMNTVNSQIVRRIEDRWIGFELSKLLKLRFGDRNHGAGRVQTPVLGWIVKRTTEYKQRMGWILNVKVGNYVYREFHREKPNIPDSTVEVEVLEEREETLLPPPPFSTDDLLIDAYRWYRIPAERVMRLAQDLFESGLITYHRTDSHHVSGKGMEIAKEYLEKVNLSQEYQPRGWGNEGTHEAIRPTRPLDVDSLKREIAENPTMLSVKFTWAHFALYDMIFRRFMASQMRESKGTIRKYRMKLGESIWEVELLVRMSGGFSNLYTYRLYDVPVGKVNAEINVVRGSDVKLLTYADVIKDMKEKRIGRPSTYAKTIQSLLRHGYVIESKRKAVLVATKKGINAYEFLSKFPDLTSEEVTADLLSKMDAISSGSLEPTTVLLPVLRELQGLETLPKSEQEI
(1035) Reverse gyrase [Metallosphaera sedula DSM 5348]
6
MNADERLPDVVYMGSCPNCGSDITSVRLGKGSVCERCLGEEIDIGSLQQLVEILQNAGTIKSLLREKNILEEERKVIDLFKRVIGSEPLGPQRSWIIRALRGESFPIIAPPGLGKTTFGIVMSLYYASRSEKSLMIFPTRTLVSQVVQKIQEMGKSLDFTPRLVYYVSGLTQSKKDELSKSLAEEDFDIFISTSRYVIQHLDEINKINYKYLFVDDVDAVLKSGKSSLTILKLMGFSDENVTKVRELLKTSRDNTSSFDEIRKIRERFAKDRVAIFSSATITRSNPVFTSLMGFKPGGATIYLRNVIDSYIIGTDIVSQTVELVKRLGPGGLVFVPVDKGLNFAREISQKIDFLKASVVSSNTTKKLEEFEQGSIDVLIGVATHYGLLVRGIDIPWRVRYAIFAGIPKFRFKLGETMHPLAMLRILTLLSVVLKDPEITRILRFVKYRLRRTSTAALAMLAKAVKDGALEDRTMIRAYEIVNTYLKDKRIVEAISKFGDISFSGDYISIPDYLTYIQASGRTSRLYGGHLTTGLSVLLVDDMILFDLLKKKLSFILDDMKWNPLDLDSQKIGDRDLQEIVKQIDKERAEIIRRRKIEPISMPMEKIKTVLLIVESPNKAKTISNFFSRPSIRDFDGLRVYETVIGDKILMVTSSGGHVYDLTTKDLGVYGVEVKSNGDVNVIPFYNTLKRCENGHQFTEYAEGGKCPICMSTNVRDKRSAINVLRRLVLEADEVLIGTDPDVEGEKIAWDLYLNLKPFNSNIFRAEFHEVTRRAITEALNSPRTFSINMLRSQLVRRIEDRWIGFKLSNKLKEEFWKEYCTKTLGNKDCDTENRNLSAGRVQTPVLGWVISRYEEYLRTKRTMYVAKAGNLNILIPKQQGIRKNSKIKIVIQSAERKQDTLGPFPAYTTDTYLSDASGFFFISAQEAMRIAQDLFENGLITYHRTDSTRISNVGIGIAESYLKDLLGERYREIFVPRSWGEGGAHEAIRPTRPLNGEQLRAMVEQGEIEPSKRLTYNHYRLYDMIFRRFLSSQLVPLVVEKEILQISAKKGDETLKLESDTLEIVTNVRLSKDVPIPSEILYIPFRSIGETLLTQIKDKLPAEIDAVITSSFQKSDHALYTQGELVSLMKQRKIGRPSTYAFIISTLLKRGYVFETMKVKRLIPSKLGQHVYEFLNSRYSNFVSEDRTRSLLERMDLIEEGKEDYRQVLKQLYNEIQDIR
(575) Reverse gyrase [Metallosphaera cuprina Ar-4]
6
MNVSDDIPNIVYIQSCPNCGSNITSLRLVQGLTCENCLADGKIKINELSELISILEEQNKIRLLQNEKNILNEEKNVVQLFRKVVGTGPIGPQRSWIIRALRGESFAIVAPPGLGKTTFGIIMSLYFASKSQKSLMMFPTKTLVSQVVQKIQEMSKLLDQPPRVLYYSSGITRSKKAEFNKSLNERDFDVLISTSRYVMENLDELNKIKYRYLFIDDVDAVLKSSKSSITILKLMGFNDDNIGKARELLRLSRDDKSSFEEIRKIRKKFMGERITIFSSATITKSNPVFTSLVGFKPGSATIYLRNVIDSFVVEENPVIQVNQIVNKLGPGGLIFVPIDRGLKYAHEIEKGIEGLNVSVLSSNSTKKLEEFENGSLDILIGVATHYGLLVRGIDIPWRVRYTLFAGIPKFRFKLGETMHPLAMLRILTILSVILKDPNVTNTLKIVKYKLRKISTAALAMLAKSVKEGDLEDRNLIKAYEIVNYYLKQKNVIEQISRFGDVSVNGDYISMPDYLTYIQASGRASRLYGGHLTTGLSVLLVDDTTLFELLKKRLSFILENLSWSPFDIENETVGGIGLKDIIKKIDSERSEIMRKREMGTISQSLGRIKSVLLIVESPNKAKTISNFFSRPSIREFEGLRVYETVMGDKILMITASEGHVYDLTTKEIGIYGVEVHSGDDSHIDAIPFYNTIKKCENGHQFTEYGEGCICPICGSKNIRDKQRSISALRELAMEVDEVLIGSDPDVEGEKIAWDLYLNLRPFNNRIYRAEFHEITRRAITESINSPRNFSVPMLRSQLVRRIEDRWIGFKLTSKLKEEFWRKYCTEFTSRNDCEAGNRNLSAGRVQTPVLGWIKNRYEEYKSTKKKVYVARFNGFSVLVPVQPGIRKNTKVKIIIEDLQRKQETIGPFPAYTTDTYLADASTFYLIPTQESMRVAQDLFESGLITYHRTDSTRISNVGINVAETFLKDMIGEKYKEIFVPRSWGEGGAHEAIRPTRPLNAEQLRVMIEQGEIEPSKRLTFNHYRLYDMIFRRFLSSQLVPLVVEKEVVKISCKKGETTLSLDSNVVEQVVKVSLQKDVGLPSDNLYIPFRSVSTSLDKVVRGTLPFELEATLTNSFIKSNSLLFTQGELVSEMKNKGIGRPSTYSSIISTLLRRGYVFESMKSKRLIPTRLGEEVYKFLSYKYGKFVSEDRTKDLLKRMDDIEEGKGDYRQVLKELYNEIKGIR
(695) Reverse gyrase [Metallosphaera cuprina Ar-4]
6
MITSVFHSSCPNCQGPLEDYRALAGLPCTNCLAGDEEPFRDLPQSEKIKAVYNLLVNNNKLAKYWELYYTAEMYDEVINYFNQVVGKEPWSLQKLWLKRLGERENFSLSAPTGMGKTTTLVAYSSYLSKGVLYIVPTKSLQEQICSKIGSISSVSCGYVDRDGISVLTVSYVNKKYESIKDYRPTFIAVDDADAIIKSGKTTDKLVELMGIPKDIYEDAMRLVRLRRSLYLKEDKDEILEKITKLERKIQGFTGAIAQLVVASATLRPKGIKQKALRYISGFDLSNTQTYARNIVDSFSCSSIEEVVQRLGPGGLILVSREYGKEKMREIKDKLTSNNFNVELAISGRKFLQNFSEGKTDILIGSASYYGVAVRGIDEPKRLRYVLFYGVPKSRARAEEAIRNPFTLMKIARLFGVNVPEDEILSLSPAEAQAIKISIIKGQVLPGKLGEVQKKLEDKISEVQEFLKSVNGIVRGETFLISRRGKDVFIEYPDVITYLQGSGRSSRLLNGGLTQGLSVILVDDQILFDLLKKKMNFIIQGFNPVQFESLNVDSITKEIERTRREGGNKIDISTGLMIVESPTKAKTISRLFGFPSRRTIGGVNVYETVIVDGNKVYILDVMATKGHMTDITLEDKGYFGVDVKNDVITPLYSHIYRCVSCKRVVSKEIDVCPYCGSSLINSSLSIVNAMRKLAMEVDEVFIATDPDTEGEKIAFDISVSVSPYNPKVRRIKYHEVTRSGIVEALRTGTSIDINTVYSQIVRRVEDRWIGFELSKLLKSKFNEGNHGAGRVQGPVLGWIVNKTREYKERIGWLLYIKVGNYVYREYHKTKPAIPDGPVQVEVVGERVETLQPPPPFSTDDLLIEAYRWFKVPAERVMRIAQDLFESGLITYHRTDSHHVSGKGIEVAKEYLEKMNFTQDLQPRSWGPEGAHEAIRPTRPLDLESLKKEIGENPMLMSVKFTWSHFAIYDMIFRRFMASQMKEAKGVFKRFAMRMKDRSWEADLLTEMEGGFSRLYKYRTYDIPIGEINPEINLSRGSDVKLLTYADVIKEMKEKNIGRPSTYAKTVQSLLRHGYVVESKKRSVLIATKKGINAYAFLSKFEDLISEKVTADLLAKMDSIVTGKAEPTSILLTVFDNLRSLEALPQSEQEI
(344) DNA topoisomerase [Metallosphaera cuprina Ar-4]
7
MRLIIAEKPSVARDIAKALGKPVRKEGYLVVGENLVTWTYGHLLQIGDLAPRKWDLKDLPFFPERFWYKAIPGKERQLKVVGTLLSKASEVVNCGDAGREGELIVREVLDYLGFKGRVLRFWTSEALTPEVVRREFMRLRDSSEFDDLYFSALARQNGDWIVGINLTRLVTLKAGGGEVWSVGRVQTPTLAMIVRRDEEIESFKPETYYVILGKFEGIEGVMLRDGVEARLGKDEAERTVSKLEKESFARVLKVDKEERSERPPLLHSLTSLQREANVLYGFTAKRTLDLAQRLYEEFKLISYPRTEARYLGDNNKGLAKEVLKRLGREELIPRVDRVGKRVFDSSRLTDHHAIIPLDKAKDDLPRQERMIYDLVLRKFLGAFMEDYEYEVQRLYLQLDGEIFLSQGKRNVRLGWMELYPHEDNPIPLPSGSVRKDEVRVEARQTKAPPRYTESTLLREMERLRLGTPATRAGIIETLIERDYVRREGKTLRSTGKGRELVKKLASSKVTSPDMTSEWEKELEEIYVKRRGREGYDEFIGKIKEFTREEVVKLLKEEFKVENRATPEMLSLAKMVSKDLGVEVPGTGMEEVKRFLDEYLPKRRITCKCGGEVRAFERGWKCVKCKSVVWREIAGKRITFKQAKALFEGKELKMRGFKSRSGKRFSAVVYLEDGKVKFKF
(1704) DNA topoisomerase [Acidianus hospitalis W1]
3
MFNLTGPSGFPVFEVEWKPLWEIDKKSYYTRKYLILLQRLCKYAKEYINACDYDIEGSVIGYMIIKNFGDLKKAKRMKFSSLTKEELIKSFNNLQPLDYNMVNAGIARHIVDWLWGINVSRALMNAVKDTSKKSVILSAGRVQSPTLIEVVKRHLDRETFVPLPYFKIELKIRLGNIINTVYLDQEFHNIDDVESLITRLKKDKLIVDKNILNKDKIIRPPPFNLGDLQLEAGRLFGLSPYRTERVGEELYLDGVISYPRTNSQKIPPTININEIVTGLSQRFGKLVDELNLMTKGKFIVRQGNKDDPAHPAIYPTGVIPKKLGKQESEVYELIVRRFLASISRDAEVTRQRIILEFEKEKLKLQLDFQKITYEGWLKIYPYHRFENEELVNVNEGSEVEIISIKPKLLLAKPSTRFTRVSLLKWMEDVKIGTEATRGKIIETLFQRKYVVTKRSYIYPTKLGIIVSEVLEKYFNELTDVKMTADMEDKLDEIIYGKKNKDEVINEVKDKISKYFEKYNEEKKIIGLELAKGLNLVAYNKCKLCDFEAMKDGLCKYHLIAKEKLDEAIKIWEDRTGYDIKMILKYIKGSKSTGKLISDLLSI
(18) Reverse gyrase [Acidianus hospitalis W1]
6
MVTSVFLKACPNCGGPLEDYRALAGLPCSKCLPGDISPFKNLSIDEKIRLIYNILVHENKLKGYWNLYYYHQLSQEIIDYFKKITGKEPWSLQKLWLRRLVEGSSFSMSAPTGMGKTTTIIVYSTYLQNSNKNVLYIVPTKSLMQQICEKMEKIGDKTSCGKVGSGISIVTVNYINRNFEEIKEYRPDFVAVDDADAIVKSGKTVDRLVTLMGIPQEVYEDAIKLVKLKRLLAIEEKRDEIETKIAEIESRISKYYGTASQLVVASATLRPKGIKQKALKYITGFDVSTAQIYARNIIDAFTSSSVVDIVNKLGSGGLILVSKEYGKDKIKEVNESLKELGFKTAIALSGRKFLEKFSSGEIDIIIGSASYYGVAVRGIDEPKRLKYVIFYGVPKSRVRLSQAIYNPYTLLKISKLFNVNIDDNLILSLSPSEAQLIKLAFLKSQKLTGKLGEIQKILEGKIDEVKSALKAVSNEVISDTFLIRKIGKEFYIEYPDAITYLQGSGRSSRLLNGGLTLGLAITIIDDFKLYEMLKRKLQYMIYNFNPTNFDSLDIGKVKNEIERSRNDKNEELHISTGLMIVESPTKARTIAKMFGAPARRNIAGVPIYETVIVDGNNVHILDIVATKGHVADLTTENIGYYGVEIRNEDKYPYYSPLYRCMNCKRVFSQEIDKCPYCGSTLISSSMSTINAIRKIAMEVEKVYIATDPDVEGEKIAFDVAANISAYNPNIYRVKYHEVTKKGILEALANPMNIDLNLVKSQIVRRIEDRWVGFELSKLLQIKFSNRNFGAGRVQTPVLGWITKRTEEYRKNMCYVASIKLGNYTHKVFLDNKNVKIDKVIVKKMEDKDDIILPLPPYTTDSLLIDAYNLYKLPAERVMKIAQELFESGLITYHRTDSIHVSNKGIEIAKEYLDKKGLIKSFIPRSWGNEGTHEAIRPTRPIDAEELKKEIEDNPQAYFIKFTWAHFAIYDMIFKRFLASQMKEAIGKYTKYQIKVLDNVSEITVLTSIKGGFSDVLKPRIYEIPEGEIQVNPIITKGSKVRLYTYAEVIKEMKDKNIGRPSTYAKIIQTLMRHGYIVESKKKYALIATKKGINVYNYLNSKFSSLVSESTTAELLEKMDMIAGGKLNADNVLTEILGQIKSLVTSLNSEQQI
(1812) Reverse gyrase [Acidianus hospitalis W1]
6
MSEELPNLVYMNSCPNCGGEITANRLYKGSACEKCVKEDIQFNSVYDLALYLLKNKNLVNLRSSYEILKELKEVERLFKRVLGSPPLGPQRSWIVRALRGESFAIIAPPGLGKTTFGILMSLYFAEKQRKTLMIFPTKTLVNQVVQRIQEMSKSLEEVPKLAYYYSGITQSQKGELNKILESGDFDIFISTSRYIINNVDYISTKDYKYLFVDDVDSVLKSSKSASAVLKLVGFTEDDIQNVRELLRKSKNSEEVYDEIRKIREKKTGDKIAIFSSATITKGNPVFSALMGFRPGSAVIYLRNVIDSYVQLPSATDEEIIDIVNKIVNKLGSGGLIFVPIDKGVSFANEIASNISGLKAEAISSTSITKLDKFEKGEIDVLVGVATHYGILVRGIDIPWRIRYAIFAGIPRFRFKIGETMHPLAMLKMLTLISLVSKDEEVTKILRIVRNKLRRISPAALVMLANSVKSGKIEDKYIQEAYDLTNKYLRNEEILEKIAEIGEISINNRYISSPDYLTYIQASGRTSRIFGGELTTGLSVLLVDNPRLFELLNRRLSIVLDEVSWNPFDIDNNKIGNNNLHEILKRIDSEREKIRKIKKEGLLTSASVKNIKTVLFIVESPNKAKTISNFFSKPSIRVFNGAIIYETVIGDKVLMVTASGGHVYDLTTKNIGIHGIEVRKNSNLEFIPYYNTIKRCNNGHQFTEYAEGNKCPTCGSTIIKDKIDVINSFRQLALEADEILIGTDPDVEGEKISWDLYLALRPYNPNIKRAEFHEVTRRAIVEAINNSRQFSIPLLQSQVVRRVEDRWIGFSLSTKLQTVFWPQYCSEVLKRTDCGENKNLSAGRVQTPVLGWVINRYNKYNETKRTVFVVKFLNSLSVLVPKQADLDKNDVKVIVYNISKSSETFGPMPPYTTDEMLSDASNLYGISAPEAMRVAQDLFEMGLITYHRTDSTRISNTGIAVAENYLKEILEDKYKEIFKPRTWGEGGAHEAIRPTRPLDENQLRALIEEGELELPKRLTLNHYRIYGLIFSRFISSQIVPLNVDKLKFNIKVLSNGKELKVENPEMDLITNVSLPGGIEVSKLSLYYPRSYFASRDSSYSDTIKKLEECIKSGQCEFTGSIASSFVKSDYQLYTQGELITEMKNKKIGRPSTYATIIATLLKRGYMLESKKVKRLVPSKLGINVYNFLTSKYSKFVSEERTRQLLELMDLIEDGKEDYRQVLKQLYDEIQSIG
(539) DNA topoisomerase [Sulfolobus solfataricus P2]
3
MNLCNVNNYYLIIAEKSKAAKKIAEALSEKPILCRKYNVSYWIIKDHNSSKYVIVPAAGHLFGLKGESGFPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKNLGDIKKAKRMKFSALTKSDILSAFRNISALDYDMINAGIARHKIDWLWGINVSRALMISLQDFAKKRVILSAGRVQSPTLVQVVNSEIERNLFIPLPKFTVSIIVKIKDYSLNIKVNKEFEKITEAKEFLNKLINKTVKVVEVENRVRLLERPSPFNLTDLQIEAGRIYGISPYNVERIAEDLYLDGLISYPRTNSQKIPSTISIYNIIKGLENSSYRKLVDLVRKITGGKYVVKQGIKDDPAHPAIHPTGEAPKNLPNSKFKIYDLIARRFLGSVSADAKLSNTIYTLKVSDFPLEFTVSYTKILERNWLDIYHFHNVKEDKPIFLSKGDEGKIVDGKVNISLSKPTSRYTKVSLLKWMESSNLGTEATRGRIIEILVKRKYLTNNGRYIIPTKLGFYIAEILNKFFPDIVDVRMTADMESKLEMIKTGKVLESKVIKENIEKLNKFIEEYKVNKDKVGESLAKALGLIKIVKCKYCDLEQYKDGLCKYHYEAKVRLLDAVEIWKERTKYDHKKILKRISSSKSTGKYVKDIVTYMLSSE
(7) Reverse gyrase 2 [Sulfolobus solfataricus P2]
6
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKIKNYWNLYYNITTFETVFKYFRDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKIDQKKVSVITISYLNKNADSIVSLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVKEKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYTENLDLSIVKELGSGGLILVSKEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFDALSNPFTLLRVGKLIGIDFSKLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLISDSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQKLFPNTTFTSLSNTNLSEIKIKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLEDIGYYGIKVEDDGTIKPYYDLIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKIAYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQTPVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKVEEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMKYKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELIQEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLSNAEGGFIKVYPVKVYNLPVGEIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLVSESTTSRLMTKLDDIALSKLNASTVLLEIFSEISTLVNPLKSEQNV
(334) Reverse gyrase [Sulfolobus acidocaldarius N8]
6
MLKVNYLFGCPNCNGSISVDRLHAGIPCETCLPGAVEKLDIRTIYDLLVKYSTLKGYSELYMDLEMYDDILRLFKKIVGGEPWSLQRYWLNKLVRGESFSLSAPTGVGKTTTLIVYSVYSHTTSLFVVPTKSLRDQICEKLKKIGHLVSCNKPEEDKVNVVTFHSINKNIDEFVRIKPKLLMVDDADMILKSGKTTERIAKVLQIPQEVFDDTIKMLRLKRMLRFKEDEDLINQVRELESKILGYKSSVQFIVSSATLKPKGYKQMALRFLVGFEPSTIQIYNRNVIDSFTYSNNVNELVKEIGDVGGLILVSKDYGKKYVDQITDNLNAEGYRAMKAISGRKFLEKFSNGDVDFLVGSASYYGVAVRGIDEPKRLKYVIFYGVPKTKLPLEDSLNNPLTALKIGELLKLDVTEYRKRLIYLSPAELQAVKIALRNKVSLNGKLGDLVEDLTKLKDIILDTIKANKIDKLVSDSFVIKKDTNKHYIFFPDIITYIQGSGRSSRIMNGGLTLGLSVVLVDDLELFDILNKKLRRIAEVTFMNFDELKLDEVREKLNKSRSDGSGGRSMNFKTALLVVESPTKARTISKIFGRGVRREIYGIPVYETIIIDDHSNTIIYTNIIASKGHLTDLTTEELGYYGVEINDKDIVVNYSPLYRCMSCGKTITKKVSTCPYCGSSMINSSEKIVNAIRLISTEVDEVYIATDPDQEGEKIAYDIYSLISPYNQNIFRISYNEITKTAVLNAIKSKAKINESLVKAQIARRIEDRWIGFELSSVLRSALNDNNNGTGRVQGPVLKWVVGKTSEYKANIGYVVDINIGDYVVRKFFKTKKDAETFISQLNVKVTKIAERTSTIDPLPPFTTDSLLIDAYSKFRINSSLAMKVAQELFEAGLITYHRTDSIHISPYGISIAREYLEKIGSNDFVGRSWGNEGAHEAIRPTRSMDVEELRKEIEENPFQFGIKFTWAHYRLYDLIFRRFIGSQMSSATATYTTYEININGELYTVELPTKVHGGFSSIYGIRVYNLDESHLTTRIRKGSLVSLLTYADVIRLMKDTNIGRPSTYVRTVQSLIRHGYVVESKKRSFLIATNKGQKVYEILNKYFSDMVSESRTSHLITKIDKINRNELSAEDVIMDLLNEIKNIKLVNPLQSEQYV
(608) Reverse gyrase [Sulfolobus islandicus Y.N.15.51]
6
MTSIDKVPPSIYTRSCPNCGGNVSSQRLFNGSACESCLKEDKEFNNLSDLINILSENNTLKNLNQLYNILEEYKEVEEIFSKLLNSSKPIGPQRSWIIRFLRGESFAIIAPPGLGKTTFGLIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSESYSYSPRILYNKQSSTQTENVLEQLKSGDFDIFVSTSRYVIQNLSELSNVKFDFIFVDDVDVALKSGKSAKAILRLVGFTDEDIQTTMKLLRENIGDEEKFGKIQEIRENKLKDKIVIFSSATISRGNPTLSSLMGFRPGSSVIYLRNIYDSYIDLTQTCKERDVDECTLGTVIRVLKRLNDGTLIFVPIDKGVQYAEYLASNLRDHGINAESVASSSISKLEKFERGEVGSLVGVATHYGVLVRGIDLPWRVKYSIFVGIPKFKFKIGEYMHPLALTRLLNLVYLVKNDDKIRGLLSYIRKRLRRISPAALAMLAKDIREGKIDDERLKEAYSLVNEYLKDTEFLKKISAVGDLVIEGDYILMPDYLTYIQASGRTSRLYGANLTTGLSVLLIDNLRLFELLNKKLNLILDEVKWYPLDIDADRLGQVSLSDIVTKITEERENLSKMKKEGRVESSAINVKTTLFIVESPNKAKTISNFFSRPSTRSYGKLRVYETVLGDRILIVAASGGHIYDLITEDDNERYDGNYVYGVLVKDNKFVPIYSTIKKCEKGHQIVKDLSENKCPICGSKIVADKTEVVDILRKLALEADEVLIGTDPDTEGEKISWDIYLAIRPFNSNIKRAEFHEVTRRAILNAIKNPREFNDNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCKSISKENTECKENRNLSAGRVQTPVLDWIVNRYQKYNENKKKYLIIESQDKSVFPFSILASKKNGLSKKTQLFIQIVDINTKEEDFGPLPPYTTDTLLTDAANLLRIPASETMRIAQDLFELGLITYHRTDSTRISNVGISVAESYLKSKQVDISKVFRPRSWGEGGAHEAIRPTKPLDETMLKASIEQGDLELSKQLTFNHFRVYNLIFRRFITSQLPPLIVTKQIVKIKAYTDDNTELDLDEGKKEFVIGYRLKEGDEFRQVLQEAIYTTFKPYQPIDEKMKGKELIGKVTSTLNKSDVQLYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMEKYKQVVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS
(973) DNA topoisomerase [Sulfolobus islandicus Y.N.15.51]
3
MNLCNVNNYYLIIAEKSKAAKKIAEALSEKPILCRKYNVNYWIIKDHDNNKYVIVPAAGHLFGLQGKSGFPVYDVDWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINACDYDIEGSVIGYLIIKYLGDTKKAKRMKFSALTKSDILLAFRNVSTLDYDMINAGVARHKIDWLWGINVSRALMISLQDFAKKRVILSAGRVQSPTLVQVVSSEIERNLFIPLPKFTVSVIVKIKDYSLNIKINKEFEKLAEANEFLNRLINKTVKVTQVENKIRILERPPPFNLTDLQVEAGRIYGISPYNVERIAEDLYLDGLISYPRTNSQKIPSTINIYNIIKGLENSSYRKLVNLVRKITGGKYIVRQGVKDDPAHPAIHPTGESPKNLPNNKFKIYDLIARRFLASVSADAKLSNTIYTLKVADFPLEFSVSYTKIPERNWLDIYHFHNVREDNPILLSKGDEGIISDGKVNISLSKPTSRYTKVSLLKWMESSDLGTEATRGRIIEILVKRRYLTSNGRYIVPTKLGFYIAELLNKFFPDIVDVRMTADMENKLEMIKTGKILESEVIKENIEKLNKFIEEYKANKDRVGESLAKALGLIKIVKCKFCDLEQYKDGLCKYHYEAKTKLLDAVRIWEERTKYDHKKILKRISSSKSTGKYVKDIVTYMLNMNDESHANLKR
(1701) Reverse gyrase [Sulfolobus islandicus Y.N.15.51]
6
MINVMYKNSCPNCGGDISADRLLNGLPCETCLPYINGIDGVDIISKVKALYNILLNNDKIKNYWNLYYNITTFEIVFKYFKDKTGYEPWSLQKLWLRRLVSNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKVDQRKVSVITISYLNKNANSITSYKPNFVAIDDADAVIKSGKTTGRLVSLLGIPNDVYESAIQLIRLRNKYYFSNEFTEEIKEKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDTYTDNLDLSIVKELGSGGLILVSKEYGRSRLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIKAKLFDALSNPFTLLRVGKMIGVNFSELQNKILVLSPSETQLLKFSIIKGETINYQKLDQLRQELLYYISLVKDKLKEIGEETLISDNFVITKQNTNYYIIYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDKHIFEILKKKMQKLFPNTNFTSLSNINLSEIKTKLEESRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRVINKVPVYETIIVDGNQIYVLDVVASKGHIVDLTLEDIGYYGIKVEDSGIIKPYYDLIKKCLDCNKTFSITSDKCPYCGSTNVQTAQTTINLLRELALSVDKVFIASDPDTEGEKIAYDLASFLSPYNSNVYRITYHEITKKAILEALRNPMKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQTPVLGWIVDKTMKYKSSMGYVVYIDIAGYSIKMYFSERKKMEEYINNLQVVKIEKISEEKILLSPLPPFTTDTLLIEANMKYKLSANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQGLIKDFVPKSWESSEEGAHEAIRPTRAMDVNELIQEIEENPYKYSIRFSKLHFLIYDLIFRRFMASQMSHAVGTKSRYLIKLNKDDNINTELLSNAEGGFIKVYPVKVYNLPLGEVKPKVNTGKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLVRHGYIVSSKRKSYLIATNRGISAYQFLSSKFYDLVSEGTTAKLMSKLDDIALSKLSASTVLLEIFSEISTLVNPLKSEQNV
Family distribution
Taxonomy tree
Sulfolobaceae