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Taxon : Thermococcus
Informations
Name
Thermococcus
Rank
genus
# topoisomerases
13
Lineage and sub-taxa
Lineage
Archaea
>
Euryarchaeota
>
Thermococci
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Thermococcales
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Thermococcaceae
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Thermococcus
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(1799) DNA topoisomerase 1 [Thermococcus gammatolerans EJ3]
3
MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVSYYEFTRDGKKVIVAPAVGHLFSLAPKTKTYGYPVFDIEWVPVYVAEKGKNYAKDYIKALATLAKRADEFIVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLKAWYNLEPTINFGMADAGIARHVLDWYWGVNLSRALTSAIKRASGKWMVLSTGRVQGPTLKFLVEREKEIQNFKPKPYWVIKMILEKNNSQYTATYEKDKIWDEEEAKRIVSEAKKGPAFVEKVEVKQQKRNPPVPFDLGTLQREAYSAFGYSPKKTLELAQRLYERGLSSYPRTSSQKLPKNLNFRSILQNIAKLPEYKPFAHELLGKGTFKPVEGKKEDPAHPAIYPTGELPKPGELTKDEQNLYDLIVRRFLALFMEPAVRESMRVIINSNGHRFILSGARTLKEGWLKVYGKYVKFDEVILPQFKEGEPVKVIQIKREKKKTKPPARYSPAAVIKKMEDLGIGTKATRAQILETLYQRGYIEGKKKIKVTPLGMRVVEALEKNVPDIVSVELTRAFEEKMEEIMAGKAKRDEVIEESKEQLIKILKVFKEKELDIGKMLLETTSKDSVKVEKSSEISGTSSRSGASKGENAKSSESSRKRLVLGKCPKCGGDLVLKYNRKTGKRFVGCSNWPKCNVTYPILQRGEVIPTGKTCCNGAPVVKIREKGREYEICLDMNCKEWKK
(488) Reverse gyrase [Thermococcus gammatolerans EJ3]
6
MKALYREMCPNCGGRISDERLYMRNPCESCLNEPIVVDSYFELVSAVRDALLKANRLKEWERIYRLESESREIEDFFKKATGFTFWSAQRTWVKRLLKGRSFSIIAPTGMGKSTFGAFMSVYYATKGKKSYIVVPTTPLVIQTIRKVQAIIERTGLDVKLAYYHGNLRKKEKEEMLAKIEGGDYDILITSAQWLARNFDEKLKGRHFDFIFVDDVDAFLKASKNIDRSLLLLGFTEEIIGKAWEIIRLKKQMARYLNGNSEDKNDRLKELNEAIEKLQREIEEFKRKNDIGIMIIASATGSARGDRIKLYRELLGFEVGSGRSALRNVVDSYLKPSKDVKEHVEELLRKLGKGGLIFVPIDQGLSYAEELVNYLREKGFAVELASSKNKKAVERFENGEADYLVGVATYYGSIVRGLDLPHLIRYAVFTGVPKFRFSIDLERPTIYRALGLLGEVMDFLDDEDRKTAEKLHARLRRLIRNIPQFELLKIEEALAEGLPIENDFHKTVLNVFRELVEFLREVLKKEDVLRRLAEDPFVSLVKEEGKWFIEIPDVRTYIQATGRTSRLFAGGITKGLSVLIVDNEKVFNGLVRQMRWRFTEFKMVPFEELDLEKLLKEIDEDREKVKLVMEGKISSKVKDLVKSALMIVESPNKARTIANFFGKPSKTRIGELVAYEVSVGDKMLTILASGGHMFDLVTNEGYHGVLIEREEDMFKFIPIYDTIKRCRDCGYQFVDWEERGVCPRCGSRNVHDALENVKAMREIAQEVDEILIATDPDTEGEKIAWDIRNVLAPYTPNIKRVEFHEVTRPAIMKAIREARDVNEARVEAQMVRRIEDRWIGFELSQELQRVFENRNLSAGRVQTPVLGWIIERYKEFTESEVYFLGLTLENGLQVTVELGKDGKDVEPPEYVTVEEVQLEERELNPSPPYTTDAMLRDASTFLKLSAPETMRLAQDLFELGLITYHRSDSTHVSSTGIEIAREYITSELGEEYFKPRPWGEEGTHEAIRPTRPIDTGRLMQLIRDGVIQLPRNLTRNHYRLYDMIFRRFMTSQMVPAKVLYEKAVINAGVGKVELEGYVEILKDGWTKLRSPPMRQLPKLEQGAKLKVVESKKWKAPKVSLYTQGDIIALMKERGIGRPSTYAKIVQTLLQRYYVFETRGRKKLVPTEKGIKVYHYLVSKYRELVSEEKTRELEEKMDLIEEGKLNYLDVLNELYREITCEIKKEGCS
(890) Reverse gyrase [Thermococcus sp. 4557]
6
MKAIYREMCPNCLGRISDERLINKNPCSECLDDTVTADSYFDLITAVRSALKLRGTLKEWERIYSLENGLREVEGFFEKATGFTFWSAQRTWVKRLLKGRSFSIIAPTGMGKSTFGAFMAVWHATRGKKSYIVVPTTPLVVQTARKIRKIAENAGVEVNLAYYHGNLRKKEKEEMLAKIQNEDYGILVTSAQWMARKFDEVLKGRHFDFIFVDDVDAFLKASKNIDRSLYLLGFNDEVIGKAWEIIRLKKQMSKYLNGRAKDREERLKELNAQIAELQRDIEEFKRENPIGIMIIASATGSARGDRIKLYRELLGFEVGSGRSALRNVADTYLKPSKDIKEHVEDLLTMLGRGGIIFTPIDQGLGYAEELADYLRERGFRIELVSSKNRKAIERFENGEADYLIGSATYYGSLVRGLDMPHLIRYAIFTGVPKFRFSIDLERPTIYRALGLLSEVMDFLSDEDRKQAEKLHARLRRLIRNIPQFELLKIEEALAEGLPIENEFHNHVLGVFRELVEFLRRVLKDEEVLRKLAEDPFISLKEEDGKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSVLIVDNEKVFNGLLRQMRWRFTEFKMVPFKELDLDEVLRQIDEDREKVRLVMEGKISAKVKDLVKSALMIVESPNKARTIANFFGQPSKTRIGDLVAYEVSIGNMMLTILASGGHMFDLVTNEGYHGVLVDEKDGMLKFIPVYDTIKRCRDCGHQFVDWEEKGVCPRCGSTNVRDALQNVKAMRELAQEVDEILIATDPDTEGEKIAWDIMNVLSPYTPNIKRIEFHEVTRPAIMRAIEEARDVNEGRVNAQIVRRIEDRWIGFELSQELQRVFENRNLSAGRVQTPVLGWVIERYKEFTESETYFMGLTLENDLRVTIELGKDGKGIEPPEYVTVEDVQLEERELKPSPPYTTDAMLKDASTFLKLSAPEAMRIAQDLFEMGLITYHRTDSTHVSNTGIEIAKEYITQELGEEYFKPRPWGEEGTHEAIRPTRPIDTGRLMQLIRDGILQLPKNLTRNHYRLYDMIFKKFMTSQMKAARIIHERAVIDAGIGKTEVEGYVEVVEDGWTRLRSPPMRQLPMLEKGARLKVVEAKKWKAPKVSLYTQGDIIALMKERKIGRPSTYAKIVQTLLQRYYAIETRGRKKLVPTDQGIKVYHYLISKYKDLVNEEKTRGLEEMMDRIEEGSVDYQEVLNALYRELQGYLGNGKPQ
(1327) DNA topoisomerase 1 [Thermococcus sp. 4557]
3
MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVGYYEFTRDGKRIIVAPAVGHLFSLAPKVKTYGYPIFDIEWVPVYVAEKGKSYAKDYIKALATLAKRADEFVVACDYDTEGEVIGYTALKYACGIDPSRAKRMKFSALTKKDLLKAWYNLEPTINFGMADAGIARHVLDWYWGVNLSRALTSAIKRASGKWQVLSTGRVQGPTLKFLVDREKEIQNFKPTPYWVIKMLLEKNGEQYTAVYEKERILDEDEAKRIVEEAKKGPAFVEKVEVKQQKRNPPVPFDLGTLQREAYSAFGYSPKKTLELAQKLYERGLTSYPRTSSQKLPKNLNFRPILQNLAKLPEYKPFAHELLGKERLKPVEGKKEDPAHPAIYPTGELPKPGDLTKDEQNLYDLIVRRFLALFMEPAVREIMKVVINSNSHRFILGGARTVKEGWLKVYGKYVKFDEVILPAFKEGEPVKVIQIKREKKKTKPPARYSPAAVIKRMEDLGIGTKATRAQILETLYSRGYIEGKRKIKVTPLGMRVVEALEKNVPDIVSVELTKAFEEKMAEIMAGKADREDVIEESKNQLIKILKVFKEKELDIGKMLMETTGTGATTSKTAARKAGAVKELSGEEEKAVKKAVDGGERRKEPLVLGKCPKCGGDLVVRYNRKTGKRFVGCSNWPKCNVTYPLLQRGEIIPTDKTCCGGAPVVKIREKGREYEICVDMNCRDWKKGKK
(846) Reverse gyrase [Thermococcus barophilus MP]
6
MKAIYREMCPNCEDRISDERLYKKHPCDVCLDREIQAEIYFDLITGIREALKLRRTLKHWENIYKLEKKLREIEDLFEKATGFNFWSAQKTWVKRLIKNKSFSIIAPTGMGKSVFGSFMALYYAKKKKKSYIVLPTTPLVVQTIKRVKTFAERAGIEINLAYYHGGMKKKEKEEMTEKIMSGDFDILITSAQWLARNFDEMLKDKRFDFIFVDDVDAFLKASKNIDRSLILLGFTEEIIQKAWEIIRLKKQMAKFLNGNSPDKQEQLKELNKQINKLEREIRKFKRENKIGVLIVASATGSARGDRIKLYRELLDFEVGSGRSALRNVVDSYLFPEKSIEEHVEELLTKLGKGGLIFVPIDQGISYAEKLTQYLQEKGFKVELVSARNKKGLEKFENEEIDYLVGVATYYGTIVRGLDLPHLIRYAIFTGVPKFRFSLDLEQPTIYRVLGLMSEVMEFLDEEDRREGERLYARLRRLIRNIPQFELMKIEEALAEGLPLEGFHSHVLEVFKQSVEFLRRVLKKEEVLKRIEEDPFVSLKEEEGKWYIEIPDVRTYIQASGRTSRLFAGGITKGLSVIIVDNEKVFNGLKRQMRWRFAEFEMKPFEELNLEELLREIDSDREKVRLILAGKISEKTKDLVKSALMIVESPNKARTIANFFGQPSKRRIGDLVAYEVSIGDRMLTILASGGHMFDLVTTEGYHGVLIEERDGKLYFIPVYDTIKRCRDCGHQFVDWEERGVCPRCGSRNVRDALENVIAMREIAQEVDEILIGTDPDVEGEKIAWDIRNVLSPYTPNIKRIEFHEVTRPAILKALNEARDVNEFRVNAQLVRRIEDRWIGFELSQKLWEVFESRNLSAGRVQTPVLGWVIQRYKEFVESETDFMALTLENGLSVTLEGVKDEVNEIIVEDVQIEEKEINPFPPYTTDTMLQDASRFLGFSAPHTMQLAQDLFELGLITYHRTDSTHVSNTGIEVAKEYISEEIGEEYFAPRKWGEEGAHECIRPTRPIDTGRLMQLLRDGIITLARGLTRDHFRLYDMIFKRFMASQMKAAKVLYEKAVIDARIAKTEIEGYVEIIFDGWTKLRAPPLKQLPRLEKGQKLKVIEVKKWRAPKVSLYTQGDLIALMKERKIGRPSTYAKIVKTLLDRHYVIETKGRKKLVPTELGTKVYHYLISKYKELVSEERTRQLEELMDLVEENKADYQEVLSNMYEEIKQYILK
(899) DNA topoisomerase 1 [Thermococcus barophilus MP]
3
MVTLIIAEKPNVAKKIAYALAERKPIRKTLYGVPYYELSRDGKKIIVAPAVGHLYTLAPKTKTYGYPIFDIEWVPVYVAEKGKSYAKDYIKALRELAKRADEFIVACDYDTEGEVIGYTALKYACGVDPKKAKRMKFSALTKRDILKAWYNLEPTINFGMADAGIARHILDWYWGVNLSRALTHAIKRASGKWMILSTGRVQGPTLKFLVEREKEIANFKPTPYWVIKMTLEKNGKQYTATYEKERILDEEEAKRIVQEAKKGPAFVEKVEVKQQKRNPPHPFDLGTLQREAYSAFGYSPKKTLDIAQRLYEMGICSYPRTSSQKLPKNLNYKYIIQSLAKIPEYKPFAHELLGKPQLKPVEGQKDDPAHPAIYPTGELPKPGELTQEEKNIYDLIVRRFLAAFADPAVREIMKVIINSNNHHFILSGARTVKEGWLKIYGKYVSFDEVILPKFREGEPVKVIQIKREKKKTKPPARYSPASVIKKMEDLGIGTKATRAQILETLYQRGYIEGKKKIRVTPLGMKVVEALEKNVPEIVSVELTREFEEKMDEIMKRKLSKDRVIEEARGQLIKILREFKAKELDIGKELMEKLLEREKNKKSKKKTAKELTAEEEEAIKNAVENHEKKSNNLIIVGKCPKCGGDLVVRYNRKTGKRFVGCSNWPSCDVTYPLLQRGKIIPTGKVCPECNAPVVKIKEGKKEYEVCLDMKCKKKMDKNKY
(726) Reverse gyrase [Thermococcus sibiricus MM 739]
6
MKAIYKGMCPNCEDKISDERLYKKHPCEICLEDEITSDTYFDLISGIREGLRVRNRIKQWEGVYSLEKKLIEAETLFKNATGFTFWSAQKTWVKRLVKGKSFSIIAPTGMGKSVFGAFMSIYYAKYGKKSYIILPTTPLVTQTIKRVKTFAENTGIDVNLAYYHGNMKKKEKEEMIQKIQTGDFDILITSGQYLARNFDLIKDKKFDFIFVDDVDAFLKASKNIDRSLILLGFNEEMIQKAWEIIKLKKLMAKYLNGNRKDKNEQLKELNKQINIIEKEIREFKDKNKIGVLIIASATGSARGDRIKLYRELLDFEVGSGRSALRNVVDSYLFPENSIEEHVKELLKVLGPGGLIFVPIDQGIAYAERLTNYLQDLGFKVELISARNKKGLQRFENGEVDYLVGVATYYGSIVRGLDIPHLIRYAIFTGIPKFRFSIDLEQPTIYRVLGLMSEVMDFLENEDRKNAEKLHAQIRRLIRNIPQFEILKIEEALAEGLPLEGFSNHVLKVFKEAVQFLRMILKKEDVLKRIEEDPFISLKKEENKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSVIIVDNEKVFNGLKRQMRWRFAEFEMRPFHELELEKLLQEIDADREKVKFLLEGKIAEKTKDLVKSALMIVESPNKARTIANFFGHPSKRRIGDLVAYEVSIGELMLTILASGGHMFDLITNDNYHGVLIKEKEGKLYFIPIYDTLKRCRECGHQFVDWESKGVCPRCGSNDVRDVLENVKAMREIAQEVDEILIGTDPDTEGEKIAWDIRNVLSPYTPTIKRIEFHEVTRPAILKALKEARDINEGRVNAQIVRRIEDRWIGFELSQKLWEVFENPYLSAGRVQTPVLSWIIQRYKEFVESEINFVQLTLENDLSVVLEDVKDGVEEVVVEDVHLEEKEINPLPPYTTDTMLQDASRFLKFSTDYTMRLAQDLFEVGLLTYIRTDSTHVSNVGIEVAKEYITDEIGEEYFVPRKWGEEGTHECIRPTRPIDTGRLMQLLRDGVITLARGLTRDHFRLYDMVFKRFMTSQMKATKVLYEKATIDARIAKAEVEGYVEILYEGWTKLRNLPLKKLPKLEKGQKIKVKETKKWKAPKVPLFSQGDIIALMKEHKIGRPSTYAKIVKTLLDRHYVIETKGRKKLVPTELGTKVYHYLITKYKDLVSEERTKQLEELMGLIEEDKIDYQEVLTELYKEIKKYTA
(1579) DNA topoisomerase 1 [Thermococcus sibiricus MM 739]
3
MTTLIIAEKPNVAKKIAYALAERKPIRKTIGKVPYYELTRDGKKIIVAPAVGHLFSLAPKERTYGYPVFDIDWVPVYLAEKGKSYTKDYIKALKELAKQADEFVIACDYDTEGEVIGYTALKYACGVEPSKAKRMKFSALTKQDLLRAWYNLEPTINFGMADAGITRHILDWYWGVNLSRALSSAIRKSSGKWHVLSTGRVQGPTLKFLVDREKEIENFVPTPYWVIKMILEKNGEQYTANYEKDRILNEEEAKRIVEEAKKGPAFVEKIEITQQKRSPPYPFDLGTLQRESYSAFGYSPKKTLEIAQKLYEKGYCLHPDSLIPTPKGVKKIEELPKEGEVFALDFDLKLSRARYRLLERDADELMYKVTLSDRTELYLTGDHPVLAYRDDRLIFVPAEELKDDDQVVLLINPWKFQSASETPKLFDFILKNASSMKDYILYDQSFGSVIRNRIKKAGLKVEILWKFKIKEPTYYKYLRGKMPVPVFKFLIERGVISKEEAREVFKGFSYSTSLSAVSFEFNEDFWYLYGFVVGDCHLDKRGQITIGARDRTEETIMAIQEVANSIGVRFAYDSRYKIIRLGSKSLVRLFELLGCPYGNKMKIFEIPGEVMAKPGWMASFLAGYYDADSHIGTKSTGGRKSLSPQIVLTSKNRRAIYTVKLMWQLLGVGTYLWERKDKNGNLMAYELKVYSRDSLKFYEIMKDHLRVKRCDLEKVRNAAIRKRKSYSHHYSVLKVTDWNGKLKSNKKLWKEFDISNQTAHGRGISLDKLRRIRDYLTDEDLRRIATGDVYILGIKSIEKFHYCGKVYDLVVEDYHNFIANGVVVHNCSYPRTSSQKLPKNLNFRSIIQNLAKIPEYKPHAHELLGKGILKPVEGKKDDPAHPAIYPTGEVPKPGDLNKDEQNLYDLIVRRFLAAFAEPAIRESMKIIINSNKHHFILNGSRTIKEGWLKIYGKYVKFDEVILPKFEKGEKVNVIQIKKEKKKTKPPARYSPASIIKKMEDLGIGTKATRAQILETLYSRGYIEGKKKIKVTPLGIKVIEALENNVPDIISVELTREFEQKMEEIMARKLKKERVIEESKTALIKVLKEFKNKEGEIGKKLLETFLENEKNKKSKRKNVKELKPEEEKVIQVEADFENKGKEKIIVGSCPKCGGDLVVRYNRRTGKRFVGCSNWPNCNVTYPLLQRGQIIPTGKTCSECGNAPIIKIKERNREYEVCLDMNCNKNRKKK
(117) DNA topoisomerase 1 [Thermococcus kodakarensis KOD1]
3
MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVSYYEFTRDGKKVIVAPAVGHLFSLAPKTKTYGYPVFDIEWVPVYVAEKGKSYAKDYIKALATLAKQADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLKAWYNMEPTINFGMADAGIARHVLDWYWGVNLSRALTSAIKRASGKWMVLSTGRVQGPTLKFLVEREKEIQNFEPKPYWVIKMLLEKNGGQYTAVYEKEKVWDEEEAKKIVEEAKKGPAFVEKVEVKQQNRNPPVPFDLGTLQREAYSAFGYSPKKTLDIAQKLYEKGYCLHPDSLIPTPQGVKRIKELPEKGEVFALDFDLKLSRARYRLLERDADEPMYKVTLSDRTELYLTADHPVLVYRDDQLIFVPAEELRENDQVVLFINRSEYSPRTESPTLLGFLLENATSMKDYILYDPEFGGVLRNRIKDAGLKTEILWRFRIREPTYYKYLRGKMPVPIVRFLLEEGVVSIEELREVFRGFSYSTSLTPISFEFSEEFWYLFGLVAGDGHLAKKGAITIPAKDRTEDTVKAVKEIANSLQVPFAFDEKYKMIILRSKSLTRLFELLGCPYGNKTEIFRIPGEIMAKPEWMAAFLAGYYDADGHIGTKPTGGKKSHSPQIVLTSKNRMAIYTVKQMWQLLGVGTYLWEKKDRNGNFMAYELKVYSRDAWRFYEVMKNHLRIKRKDLEHVKEVAIRKRKAYSHHYSVLNVKSWEGKIKSSNVLWKKFDMSNQTAHGRGISLDKLQRIVDYLTDTDLRRIAMGDVYVLGIRSIEKFHYRGKVYDLVVDQYHNFIANGVVVHNCSYPRTSSQKLPKNLNFRSIIQNLAKLPEYKPFAHELLGKESLKPVEGKKDDPAHPAIYPTGELPKPGELTKDEGNLYDLIVRRFLALFMEPAVRETMKVVINSNNHRFILSGARTLKEGWLKVYGKYVKFDEVILPAFKEGEPVKVIQIKREKKKTKPPARYSPAAVIKKMEDLGIGTKATRAQILETLYQRGYIEGKKKIKVTPLGMRVVEALEKNVPDIVSVELTRAFEEKMEEIMAGKADKDQVIEESKEQLIKILQVFKEKELDIGKMLLESTGTGVTTSKEAAKKTGAVKDANDEEKSDGKAGEGTTPKAERKPLVVGKCPKCGGDLVIRYNRKTGKRFVGCSNWPKCDVTYPILQRGQVIPTEKTCCNGAPVVKIREKGREYEICLDMNCKDWKKK
(382) Reverse gyrase [Thermococcus kodakarensis KOD1]
6
MKAVYREMCPNCWGRISDERLVMRNPCEECLDEPVHADSYFQLVSAVRNALKLRGTLKEWEKIYQLENQTREIEEFFKKATGFTFWSAQRTWVKRLLKGRSFSIIAPTGMGKSTFGAFMAVWHALKGKKSYIVVPTTPLVIQTVRKIEGIMENANADVRLAYYHGNLRKKEKEEMLERIKNEDYDILVTSAQWLARNYEEVLKGRHFDFIFVDDVDAFLKASKNIDRSLYLLGFTDEIIQKAWEIIRLKKQMSRYLNGNSEDRNEKLNGLNREIEKLQREIEKFKRKNKIGIMIIASATGSARGDRIKLYRELLGFEVGSGRSALRNVVDSYLKPTKDIKEHVEELLTRLGKGGLIFVPVDQGLGYAEELANYLSEKGFKIELVSSKNKKALEKFENGEADYLIGSATYYGSLVRGIDLPHLIRYAVFTGVPKFRFSIDLERPTIYRALGLLSEIMDFLSEEDRRQAEKLHARLRRLIRNIPQFELLKIEEALAEGLPIENEFHNHVLGVFRELVEFLRRVLRDEEVLRKLAEDPFISLVKEEGKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSVLIVDNEKVFNGLVRQMRWRFQEFKMVPFEELDLDEILRQIDEDREKVRLVMEGKISAKVKDLVRSALMIVESPNKARTIANFFGQPSKTRIGDLVAYEISVGDRMLTILASGGHMFDLVTNEGYHGVLIQNEGDMLKFIPVYDTLKRCRDCGHQFVDWEKKGVCPRCGSTNVRDALENVIAMREIAQEVDEILIATDPDTEGEKIAWDIRNVLAPYTPNIKRIEFHEVTRPAIMKAIQEARDVNENRVNAQIVRRIEDRWIGFELSQELQRVFESYNLSAGRVQTPVLGWIIERYKEFTESEVYFLGLTLENGLQVTIELGKDGKDVEPPEYVTVEEVQLEERELNPAPPYTTDAMLKDASTFLKLSAPETMRLAQDLFEAGLCVTPDTLVSLADGRIMEIKDAVEKSEGNLLSVNGLKPKEAKALKFWEIDWNGPLKVIKLKNGHEIKATPDHGLLVMREGKLGWVSAKNVREGDYVAFAYNTGHRGRDEYTLLKLMIKLGITDVMVELDEEYFNEKVAPIVRERISTSTKYKYLRRRVLPLYLLQEWGLDDYEAHVKSLYRQRAGSKPIPNFKLDGRFWYVFGLVLGDGTLRDSKVLISQTPLKDVKSVLEDVFPFLRVFETTNQVGFSNSIIAEVFRRLGARKGKLHPLVFGLREEYINAMIAGYFDTDGTFSILNDRKGPNFRGILTSKRGDVLRMLSVYLYQIGIMNYLRRDERTGVWDLIISNRSLEKFREKIYPYLRIRRAQFDEAYSVYRASRRAFEGDLLPVAPVFGKLKFKNGTKNRILKETGIDVWNWLKRPEGEIPRDKLSKVLEYAEESPEKEFLKSLVEAGVTWVKVKGVEEELYTGKLYDFTTTTENFLSNGAVSHNCTYHRTDSTHVSNTGIEVAKEYITQELGEKYFKPRPWGEEGAHEAIRPTRPIDTGRLMQLIRDGIIQLPRNLTRNHYRLYDMIFRRFMTSQMTPAKILYEKAVINAGVGKAELEGYVEIIEDGWTRLRSPPLRELPKLEKGMKLKVVEAKKWKAPKVSLYTQGDIIALMKERKIGRPSTYAKIVETLMRRGYVVETKGRKKLLPTEKGIKVYHYLVSKYRDLVSEERTRELEEIMDRIEEGIEDYIKVLGELYSEIQRYVSG
(381) Reverse gyrase [Thermococcus kodakarensis KOD1]
6
MKAVYREMCPNCWGRISDERLVMRNPCEECLDEPVHADSYFQLVSAVRNALKLRGTLKEWEKIYQLENQTREIEEFFKKATGFTFWSAQRTWVKRLLKGRSFSIIAPTGMGKSTFGAFMAVWHALKGKKSYIVVPTTPLVIQTVRKIEGIMENANADVRLAYYHGNLRKKEKEEMLERIKNEDYDILVTSAQWLARNYEEVLKGRHFDFIFVDDVDAFLKASKNIDRSLYLLGFTDEIIQKAWEIIRLKKQMSRYLNGNSEDRNEKLNGLNREIEKLQREIEKFKRKNKIGIMIIASATGSARGDRIKLYRELLGFEVGSGRSALRNVVDSYLKPTKDIKEHVEELLTRLGKGGLIFVPVDQGLGYAEELANYLSEKGFKIELVSSKNKKALEKFENGEADYLIGSATYYGSLVRGIDLPHLIRYAVFTGVPKFRFSIDLERPTIYRALGLLSEIMDFLSEEDRRQAEKLHARLRRLIRNIPQFELLKIEEALAEGLPIENEFHNHVLGVFRELVEFLRRVLRDEEVLRKLAEDPFISLVKEEGKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSVLIVDNEKVFNGLVRQMRWRFQEFKMVPFEELDLDEILRQIDEDREKVRLVMEGKISAKVKDLVRSALMIVESPNKARTIANFFGQPSKTRIGDLVAYEISVGDRMLTILASGGHMFDLVTNEGYHGVLIQNEGDMLKFIPVYDTLKRCRDCGHQFVDWEKKGVCPRCGSTNVRDALENVIAMREIAQEVDEILIATDPDTEGEKIAWDIRNVLAPYTPNIKRIEFHEVTRPAIMKAIQEARDVNENRVNAQIVRRIEDRWIGFELSQELQRVFESYNLSAGRVQTPVLGWIIERYKEFTESEVYFLGLTLENGLQVTIELGKDGKDVEPPEYVTVEEVQLEERELNPAPPYTTDAMLKDASTFLKLSAPETMRLAQDLFEAGLCVTPDTLVSLADGRIMEIKDAVEKSEGNLLSVNGLKPKEAKALKFWEIDWNGPLKVIKLKNGHEIKATPDHGLLVMREGKLGWVSAKNVREGDYVAFAYNTGHRGRDEYTLLKLMIKLGITDVMVELDEEYFNEKVAPIVRERISTSTKYKYLRRRVLPLYLLQEWGLDDYEAHVKSLYRQRAGSKPIPNFKLDGRFWYVFGLVLGDGTLRDSKVLISQTPLKDVKSVLEDVFPFLRVFETTNQVGFSNSIIAEVFRRLGARKGKLHPLVFGLREEYINAMIAGYFDTDGTFSILNDRKGPNFRGILTSKRGDVLRMLSVYLYQIGIMNYLRRDERTGVWDLIISNRSLEKFREKIYPYLRIRRAQFDEAYSVYRASRRAFEGDLLPVAPVFGKLKFKNGTKNRILKETGIDVWNWLKRPEGEIPRDKLSKVLEYAEESPEKEFLKSLVEAGVTWVKVKGVEEELYTGKLYDFTTTTENFLSNGAVSHNCTYHRTDSTHVSNTGIEVAKEYITQELGEKYFKPRPWGEEGAHEAIRPTRPIDTGRLMQLIRDGIIQLPRNLTRNHYRLYDMIFRRFMTSQMTPAKILYEKAVINAGVGKAELEGYVEIIEDGWTRLRSPPLRELPKLEKGMKLKVVEAKKWKAPKVSLYTQGDIIALMKERKIGRPSTYAKIVETLMRRGYVVETKGRKKLLPTEKGIKVYHYLVSKYRDLVSEERTRELEEIMDRIEEGIEDYIKVLGELYSEIQRYVSG
(802) Reverse gyrase [Thermococcus onnurineus NA1]
6
MKAVYREMCPNCLGRISDERLCLKNPCNECLDETAHADSYFELITAVRNALQLKGTLKEWERIYELESGVREVEAFFENATGFTFWSAQRTWVKRLLKGRSFSIIAPTGMGKSTFGAFMALWHATKGKKSYIVVPTTPLVIQTVKKIQAIAEKSGVQINLAYYHGNLRKKEKEEMLAKIENDDYQILVTSAQWLARNFDEKLKGRRFDFIFVDDVDAFLKASKNIDRSLLLLGFTEEVINKAWEIIRLKKSMAKYINGRAEDRDERLKELNREIEKLQREIEEFKEKNGVGIMIIASATGSARGDRIKLYRELLGFEVGSGRSALRNVVDSYLMPTKDIKEHVEELLTRLGKGGIIFTPIDQGLAYAEELVNYLRGKGFRIELVSSKNKKAIERFEKGEADYLIGSATYYGSLVRGLDMPHLIRYAVFTGVPKFRFSIDLERPTIYRALGLLTEVMDFLNDEQRREAEKLHARLRRLIRNIPQFELLKIEEALAEGLPIDNSFHNHVLNVFRELVEFLRKVLRDEEVLRKLAEDPFISLKEEGGKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSVLIVDNEKVFNGLVRQMRWRFTEFKMTPFEELNLDEILRQIDEDREKVRLVMEGKISAKVKDLVKSALMIVESPNKARTIANFFGQPSKRRIGDLVAYEVSIGNRMLTILASGGHMFDLVTNEGYHGVLIEEKDDMLKFIPVYDTIKRCRDCGHQFVDWEEKGICPRCGSTNVRDALENVKAMREIAQEVDEILIATDPDTEGEKIAWDIRNVLSPYTPNIKRIEFHEVTRPAILRAIEEAREVNEGRVNAQLVRRIEDRWIGFELSQELQRVFENRNLSAGRVQTPVLGWIIERYKEFTESETYFLGLTLENELSVTIELGKDAKEVEPPEEVLVEDVSLEERELNPAPPYTTDAMLKDASTFLKLSASETMRLAQDLFELGLITYHRTDSTHVSNTGIEVAKEYITQEVGEEYFRPRPWGEEGTHEAIRPTRPIDTGRLMQLIRDGIIQLSKNLTRNHYRLYDMIFKRFMTSQMKSAKVLYEKAIIDAKVGKAEIEGYVEVIEDGWTKLRSPPMRQLPRLEKGVSLKVVEAKKWKAPKVPLYTQGDIIALMKERKIGRPSTYAKIVQTLLQRYYVIETRGRKKLVPTDQGIKVYHYLISKYKELVGEEKTRELEEIMDMIEENKTDYQEVLRGLYSEIREYLK
(930) DNA topoisomerase 1 [Thermococcus onnurineus NA1]
3
MVTLIIAEKPNVARKIAYALAEGRPVRKTIGKVPYYEFTRDGKRIIVAPAVGHLFSLAPKTKTYGYPVFDIEWVPVYVAEKGKSYAKDYIKALATLAKRADEFVVACDYDTEGEVIGYTALKYACGVDPSKAKRMKFSALTKKDLLKAWYNLESTINFGMADAGIARHVLDWYWGVNLSRALTSAIKRASGKWMVLSTGRVQGPTLKFLVDREKEIQNFKPTPYWVIKMVLEKNGQQYTAVYEKERILDENEAKRIVEEAKKGPAFVEKVDVKQQNRHPPVPFDLGTLQREAYSAFGYSPKKTLELAQKLYERGLTSYPRTSSQKLPKNLNFRSILQNLAKLPEYKPFAHELLGKERLKPVEGKKDDPAHPAIYPTGELPKPGELTKDEANLYDLIVRRFLALFMEPAVREIMKVIINSNGHRFILSGARTIKEGWLKVYGKYVKFDEAILPAFKEGEPVKVLQIKREKKKTKPPARYSPAAVIKRMEDLGIGTKATRAQILETLYSRGYIEGKKKIKVTPLGMRVVEALERNVPDIVSVELTRAFEEKMEEIMAGKADKDRVIEESKEQLIKILQQFKEKELDIGKVLMETTGTGVTTSKENAKRAGTVKELSETEEKDVKKTIEKGEKTPLVVGKCPKCGGDLVVRYNRKTGKRFVGCSNWPKCNVTYPLLQRGRIIPTNKTCCDGAPVVKIREKGREYEICLDMNCKDWKKGKK
Family distribution
Taxonomy tree
Thermococcus