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Taxonomy and VLD families
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# topoisomerases
8
Lineage and sub-taxa
Lineage
Eukaryota
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Opisthokonta
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Metazoa
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Sub-taxa
Topoisomerases
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Name
Family
Sequence
(601) DNA topoisomerase 3 [Caenorhabditis elegans]
3
MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGHMMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDREGEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDLRIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFWKLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALDTVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNIWGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQDAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKIGDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLALVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVLSQSLQRYLDKNNQAGGGPGGPGGGGGPPRGPGGGGGGGPTGPPAPPKPPAKPRGRPPRKSISPAVKNGHDDPENDTIVTLSEVFGSMSNPKPARKPRAPRKSAAPKEQEEEEEVFCQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA
(602) DNA topoisomerase 3 [Caenorhabditis elegans]
3
MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGHMMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDREGEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDLRIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFWKLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALDTVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNIWGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQDAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKIGDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLALVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVLSQSLQRYLDKNNQAGGGPGGPGGGGGPPRGPGGGGGGGPTGPPAPPKPPAKPRGRPPRKSISPAVKNGHDDPENDTIVTLSEVFGSMSNPKPARKPRAPRKSAAPKEQEEEEEVFCQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA
(817) DNA topoisomerase 3-alpha [Drosophila melanogaster]
3
MKAVLTCFRPVVASHRRYCANPGQAMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPTREKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNKCPRKDEFDM
(1652) DNA topoisomerase 3-beta [Drosophila melanogaster]
3
MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYSDQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPEVTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGDIQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALPIGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV
(816) DNA topoisomerase 3-alpha [Drosophila melanogaster]
3
MKAVLTCFRPVVASHRRYCANPGQAMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPTREKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNKCPRKDEFDM
(818) DNA topoisomerase 3-alpha [Drosophila melanogaster]
3
MKAVLTCFRPVVASHRRYCANPGQAMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPTREKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNKCPRKDEFDM
(1651) DNA topoisomerase 3-beta [Drosophila melanogaster]
3
MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYSDQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPEVTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGDIQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALPIGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV
(1653) DNA topoisomerase 3-beta [Drosophila melanogaster]
3
MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYSDQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPEVTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGDIQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALPIGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV
Family distribution
Taxonomy tree
no name