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Taxon : Trypanosomatidae
Informations
Name
Trypanosomatidae
Rank
family
# topoisomerases
15
Lineage and sub-taxa
Lineage
Eukaryota
>
Euglenozoa
>
Kinetoplastida
>
Trypanosomatidae
Sub-taxa
Topoisomerases
Select all
Name
Family
Sequence
(768) DNA topoisomerase 1A [Leishmania major]
3
MLRRSVRALEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASGVTAADFPANGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPQLNAPFTRAYMHSITADGIRRAMEERHEAFDYNLANAAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDREDKIKSYLESHASTFEIQVVCYFTSKHHQRFSQVVKVTPARKGGAAPVDWSDKATVKQRCEQWALSSATHFSVSPGAKPQETVTPPPKPFTMATLIARANRQLHYSSDMVSSCLQDLFQMGYITYPRTDSTRIDESILPSIYAAVRREHGKRLLQEQDGPSKAGVRRSTAQKEAADANVEDAHEAIRPTNIDTTVEELGAVSAPMKHIYDLVRRNTMAVHMIPMKTERIVVLVACKAANGEEVEFELQGKHVVEPGWSAAFHGSKGTATPVTETDQDVEAVEDGGVVVPSISDDEFKAIMDIAAQRGGGTGVQKGSMQLESAQVAENRPSPPLPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVNKGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKPRSTKELALPPNVSDADYVLSSFISNFLNYVTEATKAQRVAITTRSLALQQEKRAASNTPMSPTDFQANLEKETKRVLTQVPDLVDNMKSYRTFTALQNSLNDYLRRNFPPSAAAMAPASSSGTARSYGSSSSSSSSTKKKESYGATYRVDKKTPRHFRAKLKKAKK
(1666) DNA topoisomerase [Leishmania major]
3
MPTWLNVAEKPSVAKEMAQSLSGGNCRTVPSQSRFNPVYEFKFEGKTMLVTSVAGHLMEDQFPPNTKNWSTYPFQGLFSAPITKYVRADLEPVKKNLEALAGRADTLVLWLDCDREGENICFEVMQVVQSKRPQVQVKRAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMDLRIGAAFTRYQTVKFRHLFAAIPGVLSFGPCQFPTLGFVVRRYWQQQGFVPEDFFTLQLQHGDTKFHSSRGSMYDQVAATLIYEDMLLAAAAEGHKGRITNVQQRPSHRRPPVPLATVVMQKLAATHLRIPSERCMALAESLYQEGLISYPRTETDSYTFQESELLELVRVQISNADVAEYATAMLADIATRVRPPLRGGRDDKAHPPIHPTKAWNATQDERGRLYNLIVRHFLASLSPDAVAATTQVSAEFGGELFSTGGTTILQRGWLDIFPYERWNSTCIPNYQIGDAFQPTAVPLKKGCTSAPPHLTETHLISLMDSNGIGTDATIAQHIKTVLDREYVKREGQSLVPTTLGIALASAYESLGLASLLQPQLRAQMELAMGDIANGAATKEQVVAAAVQLYEEIFSRLMANTNAFYEELKRYLQPEVETDACAVQATVVKANFIPCGTCGRLMDLVERAGERDREVWSVRCHACNKMHRVPNGRLNTLEPVSPPHTCPLCGFLALRVANREKQTSYHVCPHCFGSPPKAWSVTTYGCVGVAASLPDVEAAAEFRCFQCTADCPLAKGLEAIGITTCIACRQHELRLRSGANGFFLSCRGYPSCQLRVSLPAAASVKPSPSQRCPACSAVLLTFDFSGRQGVPGLNMLDTICVRCDARIKDYIAVKGMPTSGANSSAVPSAAASVASTASGTYTLPSVKPSARRSVRGGGQRGGRGGDAAAANTPSGGVDPVCGCGTPAKQLVSRKEASRGKRFLTCANRQCSFFQWLD
(55) Putative DNA topoisomerase III [Leishmania major]
3
MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYPGNFMGSPAYFKVTSTTGHVFSCDFTSQHQNWDRTDEEQLFTAPITWKDTSGKVTHHLEHEAQGCDTLVLWLDCDREGENICFEVMQVVRREIYSHHNIFRAHFSAITAEEIFQAFRNLGKPNKNISDAVTCRQELDLKVGVAFTRFQTKYFQGKYGDLDASVISYGPCQTPTLGFCVQRHDEILNFKPENFWRLVPVASRGGALLQFEWDRGRLFDETMARLILQRITKNGKVATVVNVSVSNDTRPRPTGLNTVDLMKIASRALGIGPHYVMSIAENLYIRGYISYPRTESTAYPSSFNLAGTLAQQKNHSMWGAYVTTLLQQGHARPKAGKDAGDHPPITPMRSASPGELSGDEWRIFEYITRHFIASVSPDCRLIKTKITIELGGELFSISGKVVEDPGFTEIMPHARVEDDRMPTGVHKGDSFQLSDVRLQAGQTQPPSYLTESDLIGLMEKNGIGTDASISTHVNNIVERGYCSVQAGRVMKPSKLGIVLIHGIKAIDPELVLPLVRSRVEEYVTHIAEGRAQLDDVLSYSLDLFFAKFKFFKEHIDVFDALMGASFSAISAAGKPITRCGNCMRYLKHLDTRPQRLYCPYCEVTFALPQGGAIKPYSSFTCPIDNFELVICHIEGGKSFPICPHCYNNPPFEDMRPAIQHHDRGYGGGAATTMAPSTRHMACDECRHPTCEHSLATNYVCDCVDGSCAGSMAFVPRTAGQWKVCCNKCPMMIKLPPTAQRVYVTSEECSECAANCLDIMFPEGKSVLPNRKDRIVACIFCHPGLSPLCEEVRGRIGNFRRIGGAAAGGRGGRGGRGRGRGRGRGNREDRR
(1031) DNA topoisomerase 1A [Leishmania donovani BPK282A1]
3
MLRRSVRALEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASRVTAADFPSNGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRSMFPQLNVPFTRAYMHSITAEGIRRAMEERHETFDYNLANAAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILIKDREDKIKSYLDSHASTFEIQAVCYFTSKQNHRFSQVVKVTPAHKGGAAPVDWSDEATVKQRCEQWALSSATHFSVSPGAKPQETVTPPPKPFTMATLIARANRQLHYSSDMVSLCLQDLFQMGYITYPRTDSTRIDESILPSIYAAVRREHGKRLLQEQDGPPKSGSRRSTAQKEAADANVEDAHEAIRPTNIDTTVEELGAVSAPMKHIYDLVRRNTMAVHMIPMKTERIVVLVACKAANGEEVEFELQGKHVVEPGWSAAFRGSKGTATPVTETDQDMEAVEDGGVVVPSISDDEFKAIMDFAAQRGGGTGVKKGSMQLESAQVAENRPSPPLPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVKKGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKPGSAKEWALSPNVSDADYVLSSFISNFLNYVTEATKAHRVAITTRSLALQQEKRVASNTPMSPTDFQANLVKETKRVLTQVPDLVDNMKSYRTFTALQNSLNDYLRRNFPPSAAAVAPASSSGTARSYGSSSSSVKKKESHGAACKVDKKTPRRFRAKPKKPKK
(1191) DNA topoisomerase [Leishmania donovani BPK282A1]
3
MPTWLNVAEKPSVAKEMAQSLSGGNCRTVPSQSRFNPVYEFKFEGKTMLVTSVAGHLMEDQFPPNTKNWSTYPFQGLFLAPITKYVRADLEPVKKNLEALAGRADTLVLWLDCDREGENICFEVMQVVQSKRPQVQVKRAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMDLRIGAAFTRYQTVKFRHLFAAIPGVLSFGPCQFPTLGFVVRRYWQQQGFVPEDFFTLQLQHGDTKFHSSRGSMYDQVAATLIYEDMLQAAAAEGHKGRITNVQQRPSHRRPPVPLATVVMQKLAATHLRIPSERCMTLAESLYQEGLISYPRTETDSYTFQESELLELVRVQIANADVAEYVAAMLADIATRVRPPLRGGHDDKAHPPIHPTKAWNATQDERGRLYNLIVRHFLASLSPDAVAATTQVSAEFGGELFSTGGTTILQRGWLDIFPYERWNNTCIPNYQIGDTFQPTAVPLKKGCTSAPPHLTETHLISLMDSNGIGTDATIAQHIKTVLDREYVKREGQSLVPTTLGIALASAYESLGLASLLQPQLRAQMELAMGDIANGAATKEQVVTAAVQLYEEIFSRLMANTNAFYEELKRYLQPAVETDACAVQATVVKANFIPCGTCGRLMDLVERAGERDREVWSVRCHACNKMYRVPNGRLNTLEPVSPPHTCPLCGFLALRVANREKQTSYHVCPHCFGSPPKAWSVTAYGSAGAAAPLPDVEAAAEFRCFQCTADCPLAKGLEAIGITTCIACRQHELRLRSGANGFFLSCRGYPSCHLRVSLPAAASVKPSPSQRCPACSAVLLTFDFSGRQGVPGLDMLDTICVRCDARIKDYIAVKGMPTGGANSSAVPSSAASVASTASRTYTLPSVKPSARRSVRGGGQRGGSGGDAAAANTSSGGVDPVCGCGAPAKQLVSRKEASRGKRFLTCANRQCSFFQWLD
(1702) DNA topoisomerase III, putative [Leishmania donovani BPK282A1]
3
MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYTGNFMGSPAYFKVTSTTGHVFSCDFTSQHQNWDRTDEEQLFTAPITWKDTSGKVSRHLEHEAQGCDTLVLWLDCDREGENICFEVMQVVRREIYNHHSIFRAHFSAITAEEIFHAFRNLGKPNKNISDAVTCRQELDLKVGVAFTRFQTKYFQGKYGDLDASVISYGPCQTPTLGFCVQRHDEILNFKPENFWRLVPVASRGGALLQFEWDRGRLFDETMARLILQRITKSGKVATVVNVSVSNDTRPRPTGLNTVDLMKIASRALGIGPHYVMSIAENLYIRGYISYPRTESTAYPPSFNLAGALAQQKNHSMWGAYVTALLQQGHARPKAGKDAGDHPPITPMRSASPSELSGDEWRIFEYITRHFIASVSPDCRLIKTKITIELGGELFSISGKVVEDPGFTEIMPHARVEDDRMPTGVHKGDSFQLSDVRLQAGQTQPPSYLTESDLIGLMEKNGIGTDASISTHVNNIVERGYCSVQAGRVMKPSKLGIVLIHGIKAIDPELVLPLVRSRVEEYVTHIAEGRAQLDDVLSYSLDLFFAKFKFFKEHIDVFDALMGASFSAISAAGKPITRCGNCMRYLKHLDTRPQRLYCPYCEVTFALPQGGTIKPYSSFKCPIDNFELVICHIEGGKSFPICPHCYNNPPFEDMRPAIQHHHRGYGGGAAATTAPSTRHMACDECRHPTCEHSLATNYVCDCVDGSCAGSMAFVPRTAGQWKVCCNKCPMMIKLPPTAQRVYVTSEECPECAANCLDIMFPEGKSVLPNRKDRIVACIFCHPGLSPLCEEVRGRIGNFRRIGGAAAGGRGGRGRGRGRGRGRGRGNREDRR
(57) DNA topoisomerase [Leishmania mexicana MHOM/GT/2001/U1103]
3
MPTWLNVAEKPSVAKEMAQSLSGGNCRTAQSQSRFNPVYEFKFEGKTMLVTSVAGHLMEDQFPPNTKNWSTYPFQGLFSAPITKYVRADLEPVKKNLEALASRAETLVLWLDCDREGENICFEVMQVVQSKRPQVQVKRAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMDLRIGAAFTRYQTVKFRHLFAAIPGVLSFGPCQFPTLGFVVRRYWQQQGFVPEDFFTLQLQHGDTKFHSSRGSMYDQVAATLIYEDMLQAAAADGHKGRITNVQQRPSHRRPPVPLATVVMQKLAATHLRITSERCMTLAESLYQEGLISYPRTETDSYTFQESELLELVRVQTANADVAEYATAMLADIATHVRPPLRGGHDDKAHPPIHPTKAWNATQDERGRLYNLIVRHFLASLSPDAVAATTQVSAEFGGELFSAGGTTILQRGWLDIFPYERWNNTCIPNYQIGDMFQPTAVPLKKGCTSAPPHLTETHLISLMDSNGIGTDATIAQHIKTVLDREYVRREGQSLVPTTLGIALASAYESLGLASLLQPQLRAQMELAMGDIANGAATKEQVVAAAVQLYEEIFSRLMANTNAFYEELKRYLQPAVETDACAVEATVVKANFIPCGTCGGPMDLVERAGERDREVWSVRCHACNKMHRVPNGRLNTLEPVSPPHTCPLCGFLALRVANREKQTSYHVCPHCFGSPPKAWSVSAKGAASAAAPFPDVEAAAEFRCFQCTADCPLAKGLEAIGITTCIACCQHELRLRSGAKGFFLSCRGYPSCHLRVSLPAAASVKPSPSQRCPACSAVLLTFDFSGRQGVPGLNMLDAICVRCDARIKDYITVKGMPTGDPNASAAPNSAASVASTASGTYTLPSVKPSSARRSVRGGGQRGGHGADAAATNTSSGGVDTVCGCGAPAKQFVSRKEASRGKRFLTCANRQCSFFQWLD
(1833) DNA topoisomerase 1A [Leishmania mexicana MHOM/GT/2001/U1103]
3
MLRRGVRALEKLVIVESPNKVIKVEGLLSDPKVIPDWSFSNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQPSSPASGVTAADFPANGLVVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPQLNVPFTRAYMHSITAEGIRRAMEERREAFDYNLANAAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDREDKIKSYLDSHASTFEIQAVCYFTSKHNRRFSQMVKVTPGRKGGAAPVNWSDKATVEQRCEQWALSSATHFSVSPGAKPQETVTPPPKPFTMATLIARANRQLHYSSDMVSSCLQDLFQMGYITYPRTDSTRIDESILPSIYAAVRREHGKRLLQEQDGPSKPGSRRSTAQKEAADANVEDAHEAIRPTSIDTTVEELGAVSTPMKHIYDLVRRNTMAVHMIPMKTERIVVLVMCRAANGEEVEFELQGKHVVEPGWSAAFRGSKGTVTPVTETDQDVEAVEDGGVVVPSISDDEFKAIMDVAAHRGGGTGVKKGSMQLESAQVAENRPSPPLPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVNKGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKPGSAKEWALPPNVSDADYVLSSFISNFLNYVTEATKAHRVAIATRSLTLQQEKRAASAMPMSPTDFQANLEKEAKRVVTQVPDLVDNMKSYRTFTALQNSLNDYLRRNFPPSAAAMMPASSSGTARSYGRSSSSSTKKKGSYGATYKADKKTPRRFRTKLKKPKK
(1165) Putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103]
3
MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYMGNFMGSPAYFKVTSTTGHVFSCDFTSQHQNWDRTDEEQLFTAPITWKDTSGKVTHHLEHEAQGCDTLVLWLDCDREGENICFEVMQVVRREIYNHNNIFRAHFSAITAEEIFHAFRNLGKPNKNVSDAVTCRQELDLKVGVAFTRFQTKYFQGKYGDLDASVISYGPCQTPTLGFCVQRHDEILNFKPENFWRLVPVATRGGALLQFEWDRGRLFDETMARLILQRITKNGKVATVANVSVSNDTRPRPTGLNTVDLMKIASRALGIGPHYVMSIAENLYIRGYISYPRTESTAYPPSFNLAGTLAQQKNHSMWGAYVTALLQQGHARPKAGKDAGDHPPITPMRSASPGELSGDEWRIFEYITRHFIASVSPDCRLIKTKITIELGGEFFSISGKVVEDPGFTEIMPHARVEDDRMPTGINKGDSFQLSDVRLQAGQTQPPSYLTESDLIGLMEKNGIGTDASISTHVNNIVERGYCSVQAGRVMKPSKLGIVLIHGIKAIDPELVLPLVRSRVEEYVTHIAEGRAQLDDVLSYSLDLFFSKFKFFKEHIDVFDALMGASFSAISATGKPITRCGNCMRYLKHLDTRPQRLYCPYCEVTFALPQGGAIKQYSSFKCPIDNFELVICHIEGGKSFPICPQCYNNPPFEDMRPAIQHHHRGYGGGAAATTAPSTRHMACDECRHPTCEHSLATNYVCDCVDGSCAGSMAFVPRTAGQWKVCCNKCPMMIKLPPTAQRVYVTSEECLECAANCLDIMFPEGKSVLPNRKDRIVACIFCHPGLSPLCEEVRGRIGNFRRIGGAAAGGRGGRGGRGRGRGRGRGNREDRR
(1722) DNA topoisomerase [Leishmania braziliensis]
3
MPTWLNVAEKPSVAKEMAQSLSGGHCRTVQSQSRFNPVFEFNFEGKTMLVTSVVGHLMEDQFPPNTKNWSTYPFQGLFSAPISKYVRTDLEPVKKNLEALATRADALILWLDCDREGENICFEVMQVVQSKRPQVQVKRAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMDLRIGATFTRYQTVKFRHLFAEVPGVLSFGPCQFPTLGFVVRRYWKQQGFVPEDFFTLQVQHGDTKFYSSRGSLYDQVAATLIYEDMLQAAAAEGHKGRITNVQQRPSRRRPPVPLATVIMQKLAATHLRISSERCMTLAESLYQEGLISYPRTETDSYTFQESELLELIRLQIANPDVAEYATAMLADIAARVRPPLRGGHDDKAHPPIHPTKAWNATRDERGSLYNLIVRHFLASLSPDAVAATTRVSAEFGGESFSTGGTTIVQRGWLDIFPYERWDSTCIPNYQIGDTFEPTAVLLKKGRTSAPPHLTESRLISLMDSNGIGTDATIAQHIKTVLDREYVRREGQSLVPTTLGIALASAYESLGLASLLQPQLRAQMELAMGDIANGAATKAQVVAAAVQLYEEIFSRLMASTGAFYEELKRHLRLAAETDTHAVQVTVVKDNFIQCGTCGRHMDLVERAGERDHDREVWSVRCRGCNKMHRLPNGRLNTLEPVNPPHTCPLCGFVVLRVTNREKQTSYHVCPHCFGSPPRAWNVTGCGTAGADALLPDIEAAAEFRCFQCTADCPLAKGLEAIGITTCIACHQHELRLRPGPNGFFLSCRGYPSCHLSVSLPAAASVKPSPSQRCPACNAVLLTFDFSGRQGVPGLNMLDTICIRCDARIKDYITVKGFLTGGASSSAMPSSAASVASTVTGTYTLPSVTSSARRSGRGGGQRGGRSGGAAAGEANMSTGRVDTVCGCGMPVKQLVSRKEASRGKRFLTCASRKCAFFQWLD
(1731) DNA topoisomerase 1A [Leishmania braziliensis]
3
MLRRSVRAFEKLVIVESPNKVIKVEGLLSDPKVIPDWSFSNSKLRTISTGPEKAIAMATTGHFMSLKELTWSPQLSRPAPGVTATDFPAKGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRRMFPKLSVPFTRAYMHSITADGIRRAMAERHEAFDYNLANAAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILISDREDKIKSYLDSHASTFEIQAMCHFTSKHDQRFSQVVTVTPAHKGGAAPVVWRDKVTVMHRCEQWALSSATQFSVSRTAKPQETVTPPPKPFTMATLIAKANRQLHYTSDMVSSCLQDLFQMGYITYPRTDSTRIDESILPSIYAAVRREHGKRLLQEQDGAARPSSRRSAAQKETANTNVEDAHEAIRPTNIDTTVEELGAVSAPMRHIYDLVRRNTMAVYMIPMRTERIVVPVTCRATNGEEVEFELQGKHVVEAGWSAAFRGDKGAVAPMAETDQDVQALEDGGIIVPNISDDEFKAIMDVADQRGGAGVKKGNLRLEAAQVSENRPSPPLPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYIMVNKGRCETTPVGRMLVETSRSTFPSIVDIGFTSAFEKKLDRIAKPGCVKELALPPNVSDADYVLSSFISSFLNYVTEATKAQRVAITTRSWTLQQEKSGVSSTPTDFQANLDKEKNRVMAQVPDLVDNMKNYRTFTALQNSLNDYLRRNFPPSATAVTSVSPSGIARSYGSSSTKKRSYGVTCKAAKKTPRRSHAKLKK
(332) Putative DNA topoisomerase III [Leishmania braziliensis]
3
MGRNVLMVAEKPSLAESIATILSSGSCSRRTRALPVYEYMGSFMGSPAYFKVTSTTGHVFSCDFTSQHQNWDRTEEEQLFTAPIVWKDTSEKVTHHLEHEAKGCDTLVLWLDCDREGENICFEVMQVVRREIYNNNSIFRAHFSAITAEEIFHAFCSLGRPNKSISDAVTCRQELDLKVGVAFTRFQTKYFQGKYGDLDASVVSYGPCQTPTLGFCVQRHDEILNFKPENFWRLVPVASRSGAVLQFDWDRGRVFDETMARLILQRITKNGKVATVTNMSVSSDTRPRPTGLNTVDLMKIASKALGIGPHYVMTIAENLYIRGYISYPRTESTAYPPSFNLVGALAQQKNHPIWGGYVTALLQGGHVHPKAGKDAGDHPPITPMRSASPGELSGDEWRIFEYITRHFIASVSPDCRLIKTKITIELGGELFSISGKVVEDPGFTEIMPHARVEDDRMPTGVNKGDSFQLSDVRLQAGQTQPPSYLTESDLIGLMEKNGIGTDASISTHINNIVERGYCSVQAGRVMKPSKLGIVLIHGIKAIDPELVLPLVRSRVEEYVTHIAEGRARLEDVLSYSLDLFFSKFKFFKEHIDIFDGLMGASFSAISATGKPITRCGNCMRYLKHLNTRPQRLYCPYCEVTFALPQGGTVKPYSGFTCPIDNFELVVCHIDGGKSFPICPSCYNNPPFEELPSALQHHNRGNGGGATAKAAPSTRHMACDECRHPTCEHSLATNYVCDCVDGSCPGSMAFVPRTAGQWKVCCNACPMMVKLPPTAQRVYVTAEECAECAANCLDIMFPEGKSVLPNRKDRIVACIFCHPGLSPLCEEVRGRVGNFRRIGGAAAGGRGGRGGRGRGRGRGRGNREDRW
(112) DNA topoisomerase 1A [Leishmania infantum]
3
MLRRSVRALEKLVIVESPNKVIKVEGLLSDPKVIPDWSFNNSKLRAISTGAEKAIAMATTGHFMSLKELTWSPQSSSPASRVTSADFPSNGLLVSFSLEWELIPGRRIQDTVSHYIEEKADNLTEIIVATDPDREGELIAVHAQNLIRSMFPQLNVPFTRAYMHSITAEGIRRAMEERHEAFDYNLANAAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILIKDREDKIKSYLDSHASTFEIQAVCYFTSKHNRRFSQVVKVTPAHKGGAAPVDWSDEATVKQRCEQWALNLATHFSVSPGAKPQETVTPPPKPFTMATLIARANRQLHYSSDMVSLCLQDLFQMGYITYPRTDSTRIDESILPSIYAAVRREHGKRLLQEQDGPSKSGSRRSTAQKEAADANVEDAHEAIRPTNIDTTVEELGAVSAPMKHIYDLVRRNTMAVHMIPMKTERIVVLVACKAANGEEVEFELQGKHVVEPGWSAAFRGSKGTATPVTETDQDMEAVEDGGVVVPSISDDEFKAIMDFATQRGGGTGVKKGSMQLESAQVAENRPSPPLPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVKKGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKPGSAKEWALPPNVSDADYVLSSFISNFLNYVTEATKAHRVAITTRSLVLQQEKRVASNTPMSPTDFQANLVKEAKRVLTQVPDLVDNMKSYRTFTALQNSLNDYLRRNFPPSAAAVTPASSSGTARSYGSSSSSEKKKESHGATWKVDKKTPRRFRAKPKKPKK
(750) Putative DNA topoisomerase III [Leishmania infantum]
3
MGRNVLMVAEKPSLAESIATILSNGSCSRRTRALPVYEYTGNFMGSPAYFKVTSTTGHVFSCDFTSQHQNWDRTDEEQLFTAPITWKDTSGKVSHHLEHESQGCDTLVLWLDCDREGENICFEVMQVVRREIYNHHSIFRAHFSAITAEEIFHAFRNLGKPNKNISDAVTCRQELDLKVGVAFTRFQTKYFQGKYGDLDASVISYGPCQTPTLGFCVQRHDEILNFKPENFWRLVPVASRGGALLQFEWDRGRLFDETMARLILQRITKSGKVATVVNVSVSNDTRPRPTGLNTVDLMKIASRALGIGPHYVMSIAENLYIRGYISYPRTESTAYPPSFNLAGALAQQKNHSMWGAYVTALLQQGHARPKAGKDAGDHPPITPMRSASPSELSGDEWRIFEYITRHFIASVSPDCRLIKTKITIELGGELFSISGKVVEDPGFTEIMPHARVEDDRMPTGVHKGDSFQLSDVRLQAGQTQPPSYLTESDLIGLMEKNGIGTDASISTHVNNIVERGYCSVQAGRVMKPSKLGIVLIHGIKAIDPELVLPLVRSRVEEYVTHIAEGRAQLDDVLSYSLDLFFAKFKFFKEHIDVFDALMGASFSAISAAGKPITRCGNCMRYLKHLDTRPQRLYCPYCEVTFALPQGGTIKPYSSFKCPIDNFELVICHIEGGKSFPICPHCYNNPPFEDMRPAIQHHHRGYGGGAAATTAPSTRHMACDECRHPTCEHSLATNYVCDCVDGSCAGSMAFVPRTAGQWKVCCNKCPMMIKLPPTAQRVYVTFEECPECASNCLDIMFPEGKSVLPNRKDRIVACIFCHPGLSPLCEEVRGRIGNFRRIGGAAAGGRGGRGRGRGRGRGRGRGNREDRR
(1345) DNA topoisomerase [Leishmania infantum]
3
MPTWLNVAEKPSVAKEMAQSLSGGNCRTVPSQSRFNPVYEFKFEGKTMLVTSVAGHLMEDQFPPNTKNWSTYPFQGLFSAPITKYVRADLEPVKKNLEALAGRADTLVLWLDCDREGENICFEVMQVVQSKRPQVQVKRAHFSALTARDLLNAVHNLKLPDKRLSDAVEARQEMDLRIGAAFTRYQTVKFRHLFAAIPGVLSFGPCQFPTLGFVVRRYWQQQGFVPEDFFTLQLQHGDTKFHSSRGSMYDQVAATLIYEDMLQAAAAEGHKGRITNVQQRPSHRRPPVPLATVVMQKLAATHLRIPSERCMTLAESLYQEGLISYPRTETDSYTFQESELLELVRVQIANADVAEYVAAMLADIATRVRPPLRGGHDDKAHPPIHPTKAWNATQDERGRLYNLIVRHFLASLSPDAVAATTQVSAEFGGELFSTGGTTILQRGWLDIFPYERWNNTCIPNYQIGDTFQPTAVPLKKGCTSAPPHLTETHLISLMDSNGIGTDATIAQHIKTVLDREYVKREGQSLVPTTLGIALASAYESLGLASLLQPQLRAQMELAMGDIANGAATKEQVVAAAVQLYEEIFSRLMANTNAFYEELKRYLQPAVETDACAVQATVVKANFIPCGTCGRLMDLVERAGERDREVWSVRCHACNKMYRVPNGRLNTLEPVSPPHTCPLCGFLALRVANREKKTSYHVCPHCFGSPPKAWSVTAYGSAGAAAPLPDVEAAAEFRCFQCTADCPLAKGLEAIGITTCIACRQHELRLRSGANGFFLSCRGYPSCHLRVSLPAAASVKPSPSQRCPACSAVLLTFDFSGRQGVPGLDMLDTICVRCDARIKDYIAVKGMPTGGANSSAVPSSAASVASTASRAYTLPSVKPSARRSVRGGGQRGGSSGDAAAANTSSGGVDPVCGCGAPAKQLVSRKEASRGKRFLTCAHRQCSFFQWLD
Family distribution
Taxonomy tree
Trypanosomatidae