Home | TopoIBase

Name	Family	Sequence
(XP_064393121.1) DNA topoisomerase 3-beta-1-like [Halichondria panicea]	18	MSSVLMVAEKPSLARSLAEILSKKSCNRRKTMCSACDVYEWTGHFPALRGAARFKMTSVCGHVMGLDFPAKYNRWDQVDPIELFDVETEKKESIPNLRMRDFLRSEGQGVDSLVLWLDCDKEGENICFEVIDEVKPVMRRGLPDSQVIWRAKFSAITEGAISQAFNSLGSPNWDQARSVDGRMELDLRVGCAFTRFQTKAFQSKYTGLNNSVISYGPCQTPTLGFCVQRHDEIMAFKSEKYWKLSLKVKHGSAVVTLDWSADGVFDHEVGHLLLSLVRDHTHALVVGVAEKPRSKAPPIALNTVELLRVASSRLHIGPKSTMDMAERLYIEGFISYPRTETTSYPEGFDFQTILNDLKRHTEFAEYTSSLLSIGVKVPSSGRDVGDHPPITPMRSATRAQMRDSDWRLYDYITRHFLATLSPDCKYKQTQVDFALGREAFSWSGLTPVSPGYTAIYSWHAIESSESTVKFEKGQCLEVAQLKLAEHQTTPPGYLTESELISLMEKHAIGTDASIAVHIENITTRNYVHVDSGRRLIPTKLGIVLVHGYQKIDPELVLPTIRAAVEEQLEQIALGKADYSVVVTHALDIFRRKFAYFESNIDAMDELFEASFSSVAESGRPLSKCGLCRRYLKYISSRPQRLYCAQCDQTYSLPQGGSIKLYKEIKCPLDEFELLLFTSVNGRKSYLVCPYCYNEPPFKAVSGGMSCSVCPHESCPHAKPQHRVERCSECENGVLVLEPHWQTGGTPKWKISCNSSKCKEVYVCFAGSTDVSSSPEVCPHCDSNLLSVDLTKVPNLPEAEGKHTGCWQCDPLLSELVTPFDARTDRPRPRHTGGRRGRGRRGRDRGRR
(XP_064405762.1) DNA topoisomerase 3-alpha-like isoform X2 [Halichondria panicea]	15	MVMTSVSGHLLSLDFNLAYKNWNNCTPGTLFTADVQRFCPDNFIPIKKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV
(XP_064405763.1) DNA topoisomerase 3-alpha-like isoform X3 [Halichondria panicea]	15	MTPVFWRQIGRLFWGRKGYLCCKEKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV
(XP_064405761.1) DNA topoisomerase 3-alpha-like isoform X1 [Halichondria panicea]	15	MPGYKVLNVAEKNDAAKELANVMGRGRVRRREGCSKFNKIYEFDFNLFGQNCLMVMTSVSGHLLSLDFNLAYKNWNNCTPGTLFTADVQRFCPDNFIPIKKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV
(XP_065913914.1) DNA topoisomerase 3-beta-1-like isoform X1 [Dysidea avara]	18	MNNVTHISIYLCALFGVVNKPGKHASSAMPVVLMVAEKPSLAKSLADILSRRNFNTRKSVCGACPVHEYEGSFPPGSSRRAKFKMTSVCGHVMSLDFQPCYNNWEKTDPEELFTAKTMKKEAMPNLHICKFLDIEARGVDYLVLWLDCDKEGENICYEVIDVVAPMMHQPMGSYQTIFRARFSAITEKEINKAMATLVEPDWNQSRSVDARQELDLRIGCAFTRFQTMYFQSKYSDLDSALISYGPCQTPTLGFCVQRHDIIQSFKPEKYWMIDCKLSYGSCTLSVDWTRQRIFDREAALMFLGILQEHQQAMITDVSEKLRNKSPPVALNTVDMLRVASSQLHMGPQHVMHLAEKLYTQGYISYPRTETTKYPDSFDFHSILVQFKGDAQWREHVDLLLTAKVKCPKGGKDVGDHPPITPMKCASRHELSGDSWRLYEYIVQHFIGSLSPPCQFKVTQATFGVGGEEFTWSGTQPVTPGFTAVMTWMAVASHIAQVELAKGQNWDIKQLKVSEHLTNPPDYLSESELIGLMEKHGIGTDASISVHIENICQRNYVKVDSGRRLIPTKLGIVLVHGYQKIDAELVLPTMRSAVEEQLNLIALGRADFDSVLQHSLDIFGRKFHYFRSGISGMDELFEASFTSVAEGGKPLSRCGRCIRFMRYISAKPQRLYCNTCDETYALPQGGTVKLYKELKCPLDGFELVIFSTGPKGKTYQLCPFCYNQPPFPGVPKNMGCNHCPHVTCPHALPQLSVCDCSECEDGVLVLDPASGPCWRLACNNSQCKVVASLCEGAHRVSVTEQCCACGSRLVQVDFNKANTPLADGSATHVGCPYCDGVISSRMELHHSVRGHGRGRGRGRGGRRGNRRGRGSSGRGRH
(XP_065898717.1) DNA topoisomerase 3-alpha-like [Dysidea avara]	15	MPQRVLNVAEKNDAAKELAKIMSHGRSQRREGCSKFNKIYEFDLRILGQDSRMVMTSVSGHLMTLDFIPAFQKWHSCPPGSLFTAQVMNYCPDNFLPIKKTLEQEAKKCQHLILWTDGDREGENIASEITEVCKNVRPRIQIHRARFSEITPRSIQRAYQNLEQLNVRVSQAVDTRKEVDLRIGCAFTRFQTLRLTKVFPSVLNSHTISYGPCQFPTLGFVVDRYKQVQAFVSETFYKVKVTHTTQEASCEFNWKRVRLFHHTACLVIYQICMEDPVAKVITIQRKRKSKWRPVALDTVELEKTVSRKLKINAKETMRITEKLYTRGYISYPRTETNMFPDSFDLRSVVEAQTVDRAWGGFANQVLTDGPNPRQGHKTDNAHPPIHPVRHATNLEGNEKRIYEFIVRHFLACCSQDAQGQETTVEIDIANERFTTQGLVITARNYLDVYPYETWSAKTIPQYQEGDTFQPTAMEMVEGQTTAPPLLQEADLIALMEKHGIGTDATHAEHIETIKQRQYVGVQSDGSFVPGELGMGLVEGYDSMGYELSKPFLRAEMEADLVRICEGEKRAEDVLRETIQKYTDVFNQAASQAHKLDEALSHYFGPAQSYEPSSSSDEAYYSNPVRKCPICKNSDMAIKKKRDGCYVLTCLAYPNCKAAQFFPSSVLDLSVHHSSCDQCQPQPVKKLQFKFKRGSVPPFMGEEYVGCTGCDTDLKEALSLREWLPPGHTSTHTASTGRSTTAGRALPTAGRGSGRAPPTSAAPGPSRGRGGNPSRKRKHPYNNNDDNDDNDSGCVITSVNGISQTFSSSQSSQRWNSTSRNYGTSHGSQPRPPPSFASSGYGSQSALSTSRFTGGSYSSSGMDTTGDNCVVCSCGTPAILLTVKNPSSSNLGRQFYKCSKRDGGCDFFLWADSPPTAAAPMNSTGTAPPSRFGGDSSHNYRGDTTTIGQDPTCKCGLKAVKRTVQKDGPTKGKQFYTCSKPRESQCGHFQWSDEVDQFDGGGSSSSFASSHHSGGGAPGFLPPLKKSRSNFSNATRSTNNTGAAAKRKCSVCKQEGHTKRTCPQLK
(XP_065913915.1) DNA topoisomerase 3-beta-1-like isoform X2 [Dysidea avara]	18	MMHQPMGSYQTIFRARFSAITEKEINKAMATLVEPDWNQSRSVDARQELDLRIGCAFTRFQTMYFQSKYSDLDSALISYGPCQTPTLGFCVQRHDIIQSFKPEKYWMIDCKLSYGSCTLSVDWTRQRIFDREAALMFLGILQEHQQAMITDVSEKLRNKSPPVALNTVDMLRVASSQLHMGPQHVMHLAEKLYTQGYISYPRTETTKYPDSFDFHSILVQFKGDAQWREHVDLLLTAKVKCPKGGKDVGDHPPITPMKCASRHELSGDSWRLYEYIVQHFIGSLSPPCQFKVTQATFGVGGEEFTWSGTQPVTPGFTAVMTWMAVASHIAQVELAKGQNWDIKQLKVSEHLTNPPDYLSESELIGLMEKHGIGTDASISVHIENICQRNYVKVDSGRRLIPTKLGIVLVHGYQKIDAELVLPTMRSAVEEQLNLIALGRADFDSVLQHSLDIFGRKFHYFRSGISGMDELFEASFTSVAEGGKPLSRCGRCIRFMRYISAKPQRLYCNTCDETYALPQGGTVKLYKELKCPLDGFELVIFSTGPKGKTYQLCPFCYNQPPFPGVPKNMGCNHCPHVTCPHALPQLSVCDCSECEDGVLVLDPASGPCWRLACNNSQCKVVASLCEGAHRVSVTEQCCACGSRLVQVDFNKANTPLADGSATHVGCPYCDGVISSRMELHHSVRGHGRGRGRGRGGRRGNRRGRGSSGRGRH
(XP_065178079.1) DNA topoisomerase 3-alpha-like isoform X2 [Sycon ciliatum]	15	MAQAVEARQELDFRIGCAFTRFQTMHLKRVFAGTLGHQKVISYGPCQFPTLGFVVDRYKQVQAFIPEGFFKLKVTYETEGGRMEFAWKRFRVFHRLPAEIILGLCQEQPTAKVTSVRGSNTTKYRPVALDTVEFEKLASRKLRINAKEAMRVAEKLYTSGFISYPRTETNIFPKSLNLTPLVEMQTQDHQWGEFAQRILNVYGGPNARNGRKSDNAHPPIHPTKFTNTLAGNEKTVYEFVVRHFLACVSKDAQGHETNVEIEIAEEKFTAKGLEILQRHFLDVYPYERWSDRIMPQHFEVNDTFQPTSIDLIEGETSAPPLLKEADLIALMDKHGIGTDATHAEHIETIKNRLYVGVQPDGSFVPGELGMGLVDGYDSMGFQMSKPDLRAELESDLKSICERRKQKNDVVRDMLQRYRHVFEQALAQKNLLENALSVYFGDPTNQPPPPGGGGPGGPGGGGGGGFDGGGGGGGGGLHPNPNAGEPAGPCPQCGVGQMCIREKKAGGFMIGCNCYPGCRASIFFPEIVTGLTAAKKKCDQCKPPGAVFKVKVKFKRGGAPTGLKQGYEGCYRGCDAMFASALKLTDRMRNLSRSRPATTGGAASSVSAGSRPPAPAQSLASSTAAANTHSANSREHPRSSNVSGGTFSSSSSATRGGGGSGGAGGGSHVSSSAAGRSAQGASAAGSGAQRHISAFSNDNQSHVFDHGAATTSSHHSMTSSSHHSYSAGHHQSSARPAQSSSSNGAYNPPSHNPYSSTTAAGGQHSLSSTARGQQGESNQSNSFGGDGFEGLDEEMLLEGIGDFGDDGTTSTGAGEAPVVLCRCEQRAVVKTVRKEGPNQGREFYGCPKPYKEGCDFFQWADDTATSGGGGGGFGGGGGGRGNGTGTSYESRRSSDGVSGYSNQAGGGGSGGGDGGGTVRCNCDLACAQYAVRKEGPNQGRLFYKCGKAQRESQCSFFKWVDEVTTDGASSTSNSAATSAGGFGSSSTRGWGGGGGGGGGQTNTSSGYNSAPGMLGAPGRGQKRAYAMQSSTGDDGYAGAGGGAGTGAGAGTAKKRKPPACSVCRKPGHTKRSCPMVKQYS
(XP_065178078.1) DNA topoisomerase 3-like isoform X1 [Sycon ciliatum]	15	MKVLNVAEKNDAAKALANVMGAGRSRRREGRSKYNKIYEWQMRLLNEDCDMVMTSVSGHLMEMEFAGAFRQWHGCQPLNLFDCPITKYVPENMKGIKQTLEQEIKRCTCLVLWTDGDREGENIAFEIASVCKAAKRNIDVYRARFSEITPVSIQRACRELGRIDDDMAQAVEARQELDFRIGCAFTRFQTMHLKRVFAGTLGHQKVISYGPCQFPTLGFVVDRYKQVQAFIPEGFFKLKVTYETEGGRMEFAWKRFRVFHRLPAEIILGLCQEQPTAKVTSVRGSNTTKYRPVALDTVEFEKLASRKLRINAKEAMRVAEKLYTSGFISYPRTETNIFPKSLNLTPLVEMQTQDHQWGEFAQRILNVYGGPNARNGRKSDNAHPPIHPTKFTNTLAGNEKTVYEFVVRHFLACVSKDAQGHETNVEIEIAEEKFTAKGLEILQRHFLDVYPYERWSDRIMPQHFEVNDTFQPTSIDLIEGETSAPPLLKEADLIALMDKHGIGTDATHAEHIETIKNRLYVGVQPDGSFVPGELGMGLVDGYDSMGFQMSKPDLRAELESDLKSICERRKQKNDVVRDMLQRYRHVFEQALAQKNLLENALSVYFGDPTNQPPPPGGGGPGGPGGGGGGGFDGGGGGGGGGLHPNPNAGEPAGPCPQCGVGQMCIREKKAGGFMIGCNCYPGCRASIFFPEIVTGLTAAKKKCDQCKPPGAVFKVKVKFKRGGAPTGLKQGYEGCYRGCDAMFASALKLTDRMRNLSRSRPATTGGAASSVSAGSRPPAPAQSLASSTAAANTHSANSREHPRSSNVSGGTFSSSSSATRGGGGSGGAGGGSHVSSSAAGRSAQGASAAGSGAQRHISAFSNDNQSHVFDHGAATTSSHHSMTSSSHHSYSAGHHQSSARPAQSSSSNGAYNPPSHNPYSSTTAAGGQHSLSSTARGQQGESNQSNSFGGDGFEGLDEEMLLEGIGDFGDDGTTSTGAGEAPVVLCRCEQRAVVKTVRKEGPNQGREFYGCPKPYKEGCDFFQWADDTATSGGGGGGFGGGGGGRGNGTGTSYESRRSSDGVSGYSNQAGGGGSGGGDGGGTVRCNCDLACAQYAVRKEGPNQGRLFYKCGKAQRESQCSFFKWVDEVTTDGASSTSNSAATSAGGFGSSSTRGWGGGGGGGGGQTNTSSGYNSAPGMLGAPGRGQKRAYAMQSSTGDDGYAGAGGGAGTGAGAGTAKKRKPPACSVCRKPGHTKRSCPMVKQYS
(XP_065181209.1) DNA topoisomerase 3-beta-1-like [Sycon ciliatum]	18	MKTVLMVAEKPSLATSLAKILSHGQSTSRKSSCRACQVHEYTGKFHGEPVYFKMTSVCGHVLSLDFEARFNNWDKVDPVELFSAPTEKKEASPDLNMERFLAQEARGVDYLVLWLDCDKEGENICFEVINAVKRSMNGGGRMSSVYRARFSAITDTEIRQAMQNLARPNENEARAVDARQELDLRIGCAFTRYQTRFFQGKYGDLDSTLISFGPCQTPTLAFCVERHDSIQTFKPEAFWRLDVRVQCGEHRVLSLDWERGRMFDREAVQMFAGVVRAESSATVLSVQRREKVKQRPVALNTVEMLRVASAGLGIGPSTTMMVAERLYTQGYISYPRTETTSYSSTFDLKAAIRPLERVRGMGEAVRDLLSSGGGHARGGHDVGDHPPITPLRAAGEEELGGDAWRLYQYVVAHFLASVSADCRYAATTLELRIAGELFSMTGKKVIKPGFTALLPSHAIRDDETVPDLASGAQLPVKDVRVADGQTSPPDYLTESELISLMEQHGIGTDASIPVHINNICQRNYVTVTAGRRLQPTPLGIVLVHGYQKIDRDLVQANMRGAIEKQLNLIAAGQADFDAVLEHTLATFRAKFQYFVAQIAGMDQLFEVTFSKLAESGRPLSRCGKCMRYMKYISAKPQRLYCAQCDETHALPPNGSIKLNKEIKCPLDNFELVLWSAGGRGKTYSLCPYCYSHPPFPGMKRASSCIQCYHPTCALALPKLAVAACDECEDGSLVIDPNSGPKWKMFCNTVACNVLLHLCADAFSVTVCEDALCEVCDAKLLSVQFHKDKTPLGDGETKRVACMFCDALLSSLVRWEHAVAKHPMHRRGGGGKRRGGGGHKRRSNKPKDKMAALEAYFV
(XP_062507523.1) DNA topoisomerase 3-alpha-like [Corticium candelabrum]	15	MRRLRVLNVAEKNDAAKEIARVMSRGSCRKREGRSKYNKIYEFPFDLFGNNCQMVMTSVSGHLMNNEFTTMYKSWKSCSPVALFTARIEKYCLENYLPIKATLEEEATMSDVLILWTDGDREGESIAYEIMEVCCTVNSRLDVHRARFSEITPQSIYRACQHLDVIDLHVVDAVDVRQELDLRIGAAFTRFQTLYLKKKFPEALEDKLISYGSCQFPTLGFVTERFKQIEDFVPESFHKIKVTYETTEDVVMFHWKRVRVFRKLACQILYDMCLENPTAHVLSISSRHKSKWRPQALETVELEKLSSRKLHINAKETMRIAEKLYTQGLISYPRTETNMFPSSMDLNSIIQEQTQDQHWGAFASEILAHGGATPRNGHKTDNAHPPIHPTKHTNHLQGNEQRIYELVARHFLACCSKDAHGQETTVEIEIAGERFTAQGLMITARNYLDVYPYDRWSDKTIPVFQQGQTFQPTQLEMVEGETSPPHPLQEADLIALMEKHGIGTDATHAEHIETIKLREYVGCTNDGSFLPAQLGLGLVNGYDAMGFQMSKPHLRAELEADLKHICNGVKRKEDVLPLHIDKYKDVFKRACEQAHRLDEALLEFFGEPADVPQDEVTITTGDPVVRHCPACNDADMLLRISRDGRYFIGCAGYPSCRACAFFSTSVTSVAVTEDVCSRCQPAPVVKVRLKCRRGTLPPHIVQEDGEYLVCVGGCDQTIVQALDVRVRTNTREHASIAASDQESQPFVPISQQHQRCLNSRSLQHGQSQNNRDAYSPFGCNSSGFSSSRNMSQGLGTSTGSNLAFHSDGGLHQSSAGTNSRLCSDSAIVCSCGTPAARKTTRKAGPNQGRDFFCCVNSRCNYFTWVDSEPNTSTGVSSPFTGGFSSGNLMSQHPVGDRPFVHKDTVARSQCNDVMAAGSRTFPTVMCDCGQLAARRTTHKSGPNQGRDFFCCENRSCNFFLWADSEQAAAAVSNQSSSFGGTLYGNSSDRSSGSLFSVQSSSQPTGSMQQSNSRTDDSENAVVCSCGQPAVRRTTRKAGPNQGRDFFVCMKPQESRCDFFIWADAQQGPSTWNTSLSDNSGSTWSDSKRKKVKQKGRKFYQDENDCWFGGPNTVQKRKCSNCQQIGHDRRTCPRLQ
(XP_062517426.1) DNA topoisomerase 3-beta-1-like [Corticium candelabrum]	18	MKVVLMVAEKPSLASSIAKILSRGTMQSRKSASTACQVHEFVGPFRGEPSVRFKMTSVCGHVMSLDFQGRYNNWEAVEPGELFGAPTIRKEANPNLHIEKFLQLEGRGVDYLVLWLDCDKEGENICFEVINAVQSGMKSHSRGEQTIYRAHFSSITERDINQAMKQLGSPNHNEARSVDARQELDLRIGCAFTRFQTKFFQGKYGDLDSSVISYGPCQTPTLGFCVDRHDKIQSFKPESYWQLHVQIRCDSQLVSLEWERGRIFDKEVVQVFMALVKQTTTAKVLSVQQKEKSKSRPLPLNTVEMLRVASSGLNIGPQHTMQLAERLYTQGYISYPRTETTHFAENFDIRGTLKEHVRHPSWGGVVNSLLGGNMQKPKKGHDAGDHPPITPTRCATESEIGGGDAWRLYQYITQHFIATVSPDCSYIQTTAQFDINGEQFSCSGKRVTDPGYTALLTWQAVLDSDKMPALTKGQTHEVTDVKIVDKQTSPPAFLTESELISLMEKHGIGTDASISVHINNICERNYVRVEAGRQLIPTSLGIVLVHGYQKIDPDLVLPTMRSAVEQQLNLIAAGNADYDSVLSHALGIFTHKYEYFVQHVNSMDELFEVSFSKLADTGRPMSRCGLCRHFMKFVQAKPSRLYCQHCDTVYALPQNGTIKLYKELKCPLDDFELVLWSTGAKGKSTPVCPYCYNHPPFNDMKKGMSCGECSHPTCPHALSQSKVCSCLECDQGFLLLDMTSGPKWKMACNRCNVLVHFFENASRVSTVRESCPDCGTVYLEAAFKAPSPLASGELECRGCVFCDAALSSLVQVHHAVAQHPMYHRRRGRGRGRGRRGGRGRGRGGRGPKDKMAQLDAYFV
(XP_065835336.1) DNA topoisomerase 3-beta-1-like [Oscarella lobularis]	18	MKSVLMVAEKPSLATSIAKILSHGNFKSRKSACPACQVHEYAGRFNRSEAFFKMTSVCGHVFSLDFQSRYNNWDAVDPIELFDAETEKKEANPKLHMVKFLQQEARGVDYLVLWLDCDKEGENICYEVIDSVGSFMKHTSGSQNVFRAKFSAITDKDIRQAMETLGTPNFNEARSVDARQELDLRIGCAFTRFQTRYFQGKYGDLDSSIISYGPCQTPTLGFCVERHDQIQSFKPESYWLVAVKVSVGSFGSQTVSLEWDRVRLFDREAVQMFVSRVKESKTAKVLSVQQKEKTKARPIALNTVEMLRTASSGLGIGPQHTMMLAERLYVQGYISYPRTETTHYPENFDLKGALRQLSGQSSWAPTVKDLLSGNMQTPKKGHDAGDHPPITPLRAATETELGGDAWRLYRYIVDHFIATLSRDCRYVMTTATVDVNGELFSCSGKSVTEPGYTAVMTWQAIPSDERMPDVKKGDTLNVADVKLVERQTSPPDYLTESELITLMEKHGIGTDASIPVHINNICERNYVSIASGRRLIPTTLGIVLVHGYQKIDPDLVLPTMRSAVEEQLNLICHGKADFDSVLRHTLDIFTRKFRYFVEYVTSLDELFEVSFTKLSETGKPLSKCGICRHYMKLVTAKPTRLHCKTCDKTYRLPQNGAIKLYKELKCPLDEFELVLWTTGTRGKTAPVCPNCYNYPPFPAMSKDSTCSMCTHPTCKHSMTAHKVGACWECPSGDLVLDPTSGPKWKIACNKCNVLIHLCENAFRVSKSSTPCDECSSFYLVDVDFNKTNTPLSGGETRYQGCIFCDPVLNPLVQLHHAARQHPMYHRGRGRGRRRGRGRGHRGP
(XP_065846647.1) DNA topoisomerase 3-alpha-like [Oscarella lobularis]	15	MSGWKRILNVAEKNDAAKEISTILSRGSLRRRDGRSVYNKIYEFSYNIFGANCQMLMTSVSGHLLDIEFGPLNRKWYSCPPAALFTAAIQRICPQNFVAIKETLQELAPQCQVLILWTDCDREGEGIGFEIQEVCCAANPHLDIYRARFSEITGHSIHGASQNLGRLDRRIVDAVETRRELDLRIGAAFTRFQTMRLCKVFPADLADQLISYGSCQFPTLGFVVERHKQIENFISETFHKIKVTYQTNEGLTEFNWKRGRLFLQIACEVLHDRCMENSLATVVAKTSKHKSKWRPLPLDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPLTLNLNEIIGKQTNDPNWGAFAAGILQQGGATPRRGSKTDNAHPPIHPTKYSAGLQGNEGRVYEFVVRHFLACCSKDAQGEETTVEIDIASERFTASGLSITVRNYLDVYPYDKWSEKTLPVFQQGQTFQPTSIEMIQGETSPPSLLHEADLIALMEKHGIGTDATHADHIETIKQRGYVGLLPDGGFVPGGLGMGLVDGYDSMGLQMSKPNLRAELEADLKSICEGRKQKRDVLDAMIAKYKDLFVRATAQCLKLDEALSEYFGDPQSVAENEGFAREHPVVRKCPSCKEADMTLRTKKDGGGFIIGCGHFPNCRASIFLPSSITRATVTEESCTQCQPGPVFKLRLTCRRGTLMDQYMQEDGTYLCCVFGCDESIRVALDIRTNLLRPRDSAPSLPTPSNRSTFSSSGYNSGTSSSSSSRQRRPPGGASGFRSEGNSGYSSASFASVAGSSQNLPVNCSCNVEAVRRTVRKDGPNCGREFFCCSKPQNSRCDFFLWADNAATTAPSHPPPPPPPPPPQSSNQVSCRCGQEAVKRTVRKQGPNCGREFFCCSKPQNSRCDFFLWVDDAAEASSGPMRQATQPFSSNPTTSVSCSCGQEAVRRTVRKEGPNCGRDFFGCSKPQGSSCNFFLWCDDAASSGGHQAPQIRQSNAPSNPGQVSCSCGNAAAKRTVRKTGPNQGREFFCCMTSPNGCDFFLWVDDAQDAGGGQTGRGGESFGSRGRGRDEGGRKRKCGNCHQYGHTRRKCPNI

(XP_064393121.1) DNA topoisomerase 3-beta-1-like [Halichondria panicea]

18

MSSVLMVAEKPSLARSLAEILSKKSCNRRKTMCSACDVYEWTGHFPALRGAARFKMTSVCGHVMGLDFPAKYNRWDQVDPIELFDVETEKKESIPNLRMRDFLRSEGQGVDSLVLWLDCDKEGENICFEVIDEVKPVMRRGLPDSQVIWRAKFSAITEGAISQAFNSLGSPNWDQARSVDGRMELDLRVGCAFTRFQTKAFQSKYTGLNNSVISYGPCQTPTLGFCVQRHDEIMAFKSEKYWKLSLKVKHGSAVVTLDWSADGVFDHEVGHLLLSLVRDHTHALVVGVAEKPRSKAPPIALNTVELLRVASSRLHIGPKSTMDMAERLYIEGFISYPRTETTSYPEGFDFQTILNDLKRHTEFAEYTSSLLSIGVKVPSSGRDVGDHPPITPMRSATRAQMRDSDWRLYDYITRHFLATLSPDCKYKQTQVDFALGREAFSWSGLTPVSPGYTAIYSWHAIESSESTVKFEKGQCLEVAQLKLAEHQTTPPGYLTESELISLMEKHAIGTDASIAVHIENITTRNYVHVDSGRRLIPTKLGIVLVHGYQKIDPELVLPTIRAAVEEQLEQIALGKADYSVVVTHALDIFRRKFAYFESNIDAMDELFEASFSSVAESGRPLSKCGLCRRYLKYISSRPQRLYCAQCDQTYSLPQGGSIKLYKEIKCPLDEFELLLFTSVNGRKSYLVCPYCYNEPPFKAVSGGMSCSVCPHESCPHAKPQHRVERCSECENGVLVLEPHWQTGGTPKWKISCNSSKCKEVYVCFAGSTDVSSSPEVCPHCDSNLLSVDLTKVPNLPEAEGKHTGCWQCDPLLSELVTPFDARTDRPRPRHTGGRRGRGRRGRDRGRR

(XP_064405762.1) DNA topoisomerase 3-alpha-like isoform X2 [Halichondria panicea]

15

MVMTSVSGHLLSLDFNLAYKNWNNCTPGTLFTADVQRFCPDNFIPIKKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV

(XP_064405763.1) DNA topoisomerase 3-alpha-like isoform X3 [Halichondria panicea]

15

MTPVFWRQIGRLFWGRKGYLCCKEKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV

(XP_064405761.1) DNA topoisomerase 3-alpha-like isoform X1 [Halichondria panicea]

15

MPGYKVLNVAEKNDAAKELANVMGRGRVRRREGCSKFNKIYEFDFNLFGQNCLMVMTSVSGHLLSLDFNLAYKNWNNCTPGTLFTADVQRFCPDNFIPIKKTLEREVRGCQHLVLWTDGDREGEGIAAEIVEVVTNVKSRGLQIHRARFSEITHQSIMRACANLGVVDSRVVDAVQVRQELDLRIGCAFTRFQTRRMTKAFPSVLSDQLISYGPCQFPTLGFVVERYKQVQAFIPEAFYKIKVCHEVDELKVEFNWKRVRVFNHLVCLILCQICLENPTALVLGTTSRPRSKWRPLPMDTVELEKLASRKLRISAKETMKIAEKLYTQGYISYPRTETNIFPDSFDLNAIVQAQAGDPQWGDFAGNILTRGATPRQGAKTDNAHPPIHPTKYTNTLQGNEQRIYELVVRHFLACCSQDARGQETTVDIEIAKEKFSAQGLMIIERNYLDVYPYDRWSTKVIPVYNQGSTFQPSSIEMVEGETTPPPLLHEADLITLMEKYGIGTDATHAEHIETIKTRNYVGVQHDDSLVPGELGMGLVEGYDSMGFELSKPQLRAELEADLKRICEGSKTRDDVLSSTLEKYHEVFQNAYQQANKLEESLSKYFGPSQPIAEDEPPSLGEVIRRCPLCQQNDLVIKRKRDGGYMLSCLGFPGCRAVQFFPASVLDVKMDPSLCSTCQPPPVHHLALSLKPGSVPPYLGSQLVGCSSCDPCFRNELDIRPIRSSGDNSGGGSRSQTSSSQSRGGARGSSSRGANHRGSSSRGANYRGGPSPRGRGSSRKRPHPDSWGGPEDPQSLSAPSRRPALFGISGSLSSADNQTLCVCGEPAILLTVRKEDSSNKGRQFYKCAKRDGGCDFFLWADEPPPTPTNDNWSHPPPSRNTHPSHNTQPSRNTQRSYSDARGSNPITCNCGLDAVQKTVQKDGPNKGKLFHTCSKPRDEQCGYFEWCKGASTSSRGRGRGGRQQRGAGGGEKKTRTCSVCRQPGHTKRSCPRQKELV

(XP_065913914.1) DNA topoisomerase 3-beta-1-like isoform X1 [Dysidea avara]

18

MNNVTHISIYLCALFGVVNKPGKHASSAMPVVLMVAEKPSLAKSLADILSRRNFNTRKSVCGACPVHEYEGSFPPGSSRRAKFKMTSVCGHVMSLDFQPCYNNWEKTDPEELFTAKTMKKEAMPNLHICKFLDIEARGVDYLVLWLDCDKEGENICYEVIDVVAPMMHQPMGSYQTIFRARFSAITEKEINKAMATLVEPDWNQSRSVDARQELDLRIGCAFTRFQTMYFQSKYSDLDSALISYGPCQTPTLGFCVQRHDIIQSFKPEKYWMIDCKLSYGSCTLSVDWTRQRIFDREAALMFLGILQEHQQAMITDVSEKLRNKSPPVALNTVDMLRVASSQLHMGPQHVMHLAEKLYTQGYISYPRTETTKYPDSFDFHSILVQFKGDAQWREHVDLLLTAKVKCPKGGKDVGDHPPITPMKCASRHELSGDSWRLYEYIVQHFIGSLSPPCQFKVTQATFGVGGEEFTWSGTQPVTPGFTAVMTWMAVASHIAQVELAKGQNWDIKQLKVSEHLTNPPDYLSESELIGLMEKHGIGTDASISVHIENICQRNYVKVDSGRRLIPTKLGIVLVHGYQKIDAELVLPTMRSAVEEQLNLIALGRADFDSVLQHSLDIFGRKFHYFRSGISGMDELFEASFTSVAEGGKPLSRCGRCIRFMRYISAKPQRLYCNTCDETYALPQGGTVKLYKELKCPLDGFELVIFSTGPKGKTYQLCPFCYNQPPFPGVPKNMGCNHCPHVTCPHALPQLSVCDCSECEDGVLVLDPASGPCWRLACNNSQCKVVASLCEGAHRVSVTEQCCACGSRLVQVDFNKANTPLADGSATHVGCPYCDGVISSRMELHHSVRGHGRGRGRGRGGRRGNRRGRGSSGRGRH

(XP_065898717.1) DNA topoisomerase 3-alpha-like [Dysidea avara]

15

MPQRVLNVAEKNDAAKELAKIMSHGRSQRREGCSKFNKIYEFDLRILGQDSRMVMTSVSGHLMTLDFIPAFQKWHSCPPGSLFTAQVMNYCPDNFLPIKKTLEQEAKKCQHLILWTDGDREGENIASEITEVCKNVRPRIQIHRARFSEITPRSIQRAYQNLEQLNVRVSQAVDTRKEVDLRIGCAFTRFQTLRLTKVFPSVLNSHTISYGPCQFPTLGFVVDRYKQVQAFVSETFYKVKVTHTTQEASCEFNWKRVRLFHHTACLVIYQICMEDPVAKVITIQRKRKSKWRPVALDTVELEKTVSRKLKINAKETMRITEKLYTRGYISYPRTETNMFPDSFDLRSVVEAQTVDRAWGGFANQVLTDGPNPRQGHKTDNAHPPIHPVRHATNLEGNEKRIYEFIVRHFLACCSQDAQGQETTVEIDIANERFTTQGLVITARNYLDVYPYETWSAKTIPQYQEGDTFQPTAMEMVEGQTTAPPLLQEADLIALMEKHGIGTDATHAEHIETIKQRQYVGVQSDGSFVPGELGMGLVEGYDSMGYELSKPFLRAEMEADLVRICEGEKRAEDVLRETIQKYTDVFNQAASQAHKLDEALSHYFGPAQSYEPSSSSDEAYYSNPVRKCPICKNSDMAIKKKRDGCYVLTCLAYPNCKAAQFFPSSVLDLSVHHSSCDQCQPQPVKKLQFKFKRGSVPPFMGEEYVGCTGCDTDLKEALSLREWLPPGHTSTHTASTGRSTTAGRALPTAGRGSGRAPPTSAAPGPSRGRGGNPSRKRKHPYNNNDDNDDNDSGCVITSVNGISQTFSSSQSSQRWNSTSRNYGTSHGSQPRPPPSFASSGYGSQSALSTSRFTGGSYSSSGMDTTGDNCVVCSCGTPAILLTVKNPSSSNLGRQFYKCSKRDGGCDFFLWADSPPTAAAPMNSTGTAPPSRFGGDSSHNYRGDTTTIGQDPTCKCGLKAVKRTVQKDGPTKGKQFYTCSKPRESQCGHFQWSDEVDQFDGGGSSSSFASSHHSGGGAPGFLPPLKKSRSNFSNATRSTNNTGAAAKRKCSVCKQEGHTKRTCPQLK

(XP_065913915.1) DNA topoisomerase 3-beta-1-like isoform X2 [Dysidea avara]

18

MMHQPMGSYQTIFRARFSAITEKEINKAMATLVEPDWNQSRSVDARQELDLRIGCAFTRFQTMYFQSKYSDLDSALISYGPCQTPTLGFCVQRHDIIQSFKPEKYWMIDCKLSYGSCTLSVDWTRQRIFDREAALMFLGILQEHQQAMITDVSEKLRNKSPPVALNTVDMLRVASSQLHMGPQHVMHLAEKLYTQGYISYPRTETTKYPDSFDFHSILVQFKGDAQWREHVDLLLTAKVKCPKGGKDVGDHPPITPMKCASRHELSGDSWRLYEYIVQHFIGSLSPPCQFKVTQATFGVGGEEFTWSGTQPVTPGFTAVMTWMAVASHIAQVELAKGQNWDIKQLKVSEHLTNPPDYLSESELIGLMEKHGIGTDASISVHIENICQRNYVKVDSGRRLIPTKLGIVLVHGYQKIDAELVLPTMRSAVEEQLNLIALGRADFDSVLQHSLDIFGRKFHYFRSGISGMDELFEASFTSVAEGGKPLSRCGRCIRFMRYISAKPQRLYCNTCDETYALPQGGTVKLYKELKCPLDGFELVIFSTGPKGKTYQLCPFCYNQPPFPGVPKNMGCNHCPHVTCPHALPQLSVCDCSECEDGVLVLDPASGPCWRLACNNSQCKVVASLCEGAHRVSVTEQCCACGSRLVQVDFNKANTPLADGSATHVGCPYCDGVISSRMELHHSVRGHGRGRGRGRGGRRGNRRGRGSSGRGRH

(XP_065178079.1) DNA topoisomerase 3-alpha-like isoform X2 [Sycon ciliatum]

15

MAQAVEARQELDFRIGCAFTRFQTMHLKRVFAGTLGHQKVISYGPCQFPTLGFVVDRYKQVQAFIPEGFFKLKVTYETEGGRMEFAWKRFRVFHRLPAEIILGLCQEQPTAKVTSVRGSNTTKYRPVALDTVEFEKLASRKLRINAKEAMRVAEKLYTSGFISYPRTETNIFPKSLNLTPLVEMQTQDHQWGEFAQRILNVYGGPNARNGRKSDNAHPPIHPTKFTNTLAGNEKTVYEFVVRHFLACVSKDAQGHETNVEIEIAEEKFTAKGLEILQRHFLDVYPYERWSDRIMPQHFEVNDTFQPTSIDLIEGETSAPPLLKEADLIALMDKHGIGTDATHAEHIETIKNRLYVGVQPDGSFVPGELGMGLVDGYDSMGFQMSKPDLRAELESDLKSICERRKQKNDVVRDMLQRYRHVFEQALAQKNLLENALSVYFGDPTNQPPPPGGGGPGGPGGGGGGGFDGGGGGGGGGLHPNPNAGEPAGPCPQCGVGQMCIREKKAGGFMIGCNCYPGCRASIFFPEIVTGLTAAKKKCDQCKPPGAVFKVKVKFKRGGAPTGLKQGYEGCYRGCDAMFASALKLTDRMRNLSRSRPATTGGAASSVSAGSRPPAPAQSLASSTAAANTHSANSREHPRSSNVSGGTFSSSSSATRGGGGSGGAGGGSHVSSSAAGRSAQGASAAGSGAQRHISAFSNDNQSHVFDHGAATTSSHHSMTSSSHHSYSAGHHQSSARPAQSSSSNGAYNPPSHNPYSSTTAAGGQHSLSSTARGQQGESNQSNSFGGDGFEGLDEEMLLEGIGDFGDDGTTSTGAGEAPVVLCRCEQRAVVKTVRKEGPNQGREFYGCPKPYKEGCDFFQWADDTATSGGGGGGFGGGGGGRGNGTGTSYESRRSSDGVSGYSNQAGGGGSGGGDGGGTVRCNCDLACAQYAVRKEGPNQGRLFYKCGKAQRESQCSFFKWVDEVTTDGASSTSNSAATSAGGFGSSSTRGWGGGGGGGGGQTNTSSGYNSAPGMLGAPGRGQKRAYAMQSSTGDDGYAGAGGGAGTGAGAGTAKKRKPPACSVCRKPGHTKRSCPMVKQYS

(XP_065178078.1) DNA topoisomerase 3-like isoform X1 [Sycon ciliatum]

15

MKVLNVAEKNDAAKALANVMGAGRSRRREGRSKYNKIYEWQMRLLNEDCDMVMTSVSGHLMEMEFAGAFRQWHGCQPLNLFDCPITKYVPENMKGIKQTLEQEIKRCTCLVLWTDGDREGENIAFEIASVCKAAKRNIDVYRARFSEITPVSIQRACRELGRIDDDMAQAVEARQELDFRIGCAFTRFQTMHLKRVFAGTLGHQKVISYGPCQFPTLGFVVDRYKQVQAFIPEGFFKLKVTYETEGGRMEFAWKRFRVFHRLPAEIILGLCQEQPTAKVTSVRGSNTTKYRPVALDTVEFEKLASRKLRINAKEAMRVAEKLYTSGFISYPRTETNIFPKSLNLTPLVEMQTQDHQWGEFAQRILNVYGGPNARNGRKSDNAHPPIHPTKFTNTLAGNEKTVYEFVVRHFLACVSKDAQGHETNVEIEIAEEKFTAKGLEILQRHFLDVYPYERWSDRIMPQHFEVNDTFQPTSIDLIEGETSAPPLLKEADLIALMDKHGIGTDATHAEHIETIKNRLYVGVQPDGSFVPGELGMGLVDGYDSMGFQMSKPDLRAELESDLKSICERRKQKNDVVRDMLQRYRHVFEQALAQKNLLENALSVYFGDPTNQPPPPGGGGPGGPGGGGGGGFDGGGGGGGGGLHPNPNAGEPAGPCPQCGVGQMCIREKKAGGFMIGCNCYPGCRASIFFPEIVTGLTAAKKKCDQCKPPGAVFKVKVKFKRGGAPTGLKQGYEGCYRGCDAMFASALKLTDRMRNLSRSRPATTGGAASSVSAGSRPPAPAQSLASSTAAANTHSANSREHPRSSNVSGGTFSSSSSATRGGGGSGGAGGGSHVSSSAAGRSAQGASAAGSGAQRHISAFSNDNQSHVFDHGAATTSSHHSMTSSSHHSYSAGHHQSSARPAQSSSSNGAYNPPSHNPYSSTTAAGGQHSLSSTARGQQGESNQSNSFGGDGFEGLDEEMLLEGIGDFGDDGTTSTGAGEAPVVLCRCEQRAVVKTVRKEGPNQGREFYGCPKPYKEGCDFFQWADDTATSGGGGGGFGGGGGGRGNGTGTSYESRRSSDGVSGYSNQAGGGGSGGGDGGGTVRCNCDLACAQYAVRKEGPNQGRLFYKCGKAQRESQCSFFKWVDEVTTDGASSTSNSAATSAGGFGSSSTRGWGGGGGGGGGQTNTSSGYNSAPGMLGAPGRGQKRAYAMQSSTGDDGYAGAGGGAGTGAGAGTAKKRKPPACSVCRKPGHTKRSCPMVKQYS

(XP_065181209.1) DNA topoisomerase 3-beta-1-like [Sycon ciliatum]

18

MKTVLMVAEKPSLATSLAKILSHGQSTSRKSSCRACQVHEYTGKFHGEPVYFKMTSVCGHVLSLDFEARFNNWDKVDPVELFSAPTEKKEASPDLNMERFLAQEARGVDYLVLWLDCDKEGENICFEVINAVKRSMNGGGRMSSVYRARFSAITDTEIRQAMQNLARPNENEARAVDARQELDLRIGCAFTRYQTRFFQGKYGDLDSTLISFGPCQTPTLAFCVERHDSIQTFKPEAFWRLDVRVQCGEHRVLSLDWERGRMFDREAVQMFAGVVRAESSATVLSVQRREKVKQRPVALNTVEMLRVASAGLGIGPSTTMMVAERLYTQGYISYPRTETTSYSSTFDLKAAIRPLERVRGMGEAVRDLLSSGGGHARGGHDVGDHPPITPLRAAGEEELGGDAWRLYQYVVAHFLASVSADCRYAATTLELRIAGELFSMTGKKVIKPGFTALLPSHAIRDDETVPDLASGAQLPVKDVRVADGQTSPPDYLTESELISLMEQHGIGTDASIPVHINNICQRNYVTVTAGRRLQPTPLGIVLVHGYQKIDRDLVQANMRGAIEKQLNLIAAGQADFDAVLEHTLATFRAKFQYFVAQIAGMDQLFEVTFSKLAESGRPLSRCGKCMRYMKYISAKPQRLYCAQCDETHALPPNGSIKLNKEIKCPLDNFELVLWSAGGRGKTYSLCPYCYSHPPFPGMKRASSCIQCYHPTCALALPKLAVAACDECEDGSLVIDPNSGPKWKMFCNTVACNVLLHLCADAFSVTVCEDALCEVCDAKLLSVQFHKDKTPLGDGETKRVACMFCDALLSSLVRWEHAVAKHPMHRRGGGGKRRGGGGHKRRSNKPKDKMAALEAYFV

(XP_062507523.1) DNA topoisomerase 3-alpha-like [Corticium candelabrum]

15

MRRLRVLNVAEKNDAAKEIARVMSRGSCRKREGRSKYNKIYEFPFDLFGNNCQMVMTSVSGHLMNNEFTTMYKSWKSCSPVALFTARIEKYCLENYLPIKATLEEEATMSDVLILWTDGDREGESIAYEIMEVCCTVNSRLDVHRARFSEITPQSIYRACQHLDVIDLHVVDAVDVRQELDLRIGAAFTRFQTLYLKKKFPEALEDKLISYGSCQFPTLGFVTERFKQIEDFVPESFHKIKVTYETTEDVVMFHWKRVRVFRKLACQILYDMCLENPTAHVLSISSRHKSKWRPQALETVELEKLSSRKLHINAKETMRIAEKLYTQGLISYPRTETNMFPSSMDLNSIIQEQTQDQHWGAFASEILAHGGATPRNGHKTDNAHPPIHPTKHTNHLQGNEQRIYELVARHFLACCSKDAHGQETTVEIEIAGERFTAQGLMITARNYLDVYPYDRWSDKTIPVFQQGQTFQPTQLEMVEGETSPPHPLQEADLIALMEKHGIGTDATHAEHIETIKLREYVGCTNDGSFLPAQLGLGLVNGYDAMGFQMSKPHLRAELEADLKHICNGVKRKEDVLPLHIDKYKDVFKRACEQAHRLDEALLEFFGEPADVPQDEVTITTGDPVVRHCPACNDADMLLRISRDGRYFIGCAGYPSCRACAFFSTSVTSVAVTEDVCSRCQPAPVVKVRLKCRRGTLPPHIVQEDGEYLVCVGGCDQTIVQALDVRVRTNTREHASIAASDQESQPFVPISQQHQRCLNSRSLQHGQSQNNRDAYSPFGCNSSGFSSSRNMSQGLGTSTGSNLAFHSDGGLHQSSAGTNSRLCSDSAIVCSCGTPAARKTTRKAGPNQGRDFFCCVNSRCNYFTWVDSEPNTSTGVSSPFTGGFSSGNLMSQHPVGDRPFVHKDTVARSQCNDVMAAGSRTFPTVMCDCGQLAARRTTHKSGPNQGRDFFCCENRSCNFFLWADSEQAAAAVSNQSSSFGGTLYGNSSDRSSGSLFSVQSSSQPTGSMQQSNSRTDDSENAVVCSCGQPAVRRTTRKAGPNQGRDFFVCMKPQESRCDFFIWADAQQGPSTWNTSLSDNSGSTWSDSKRKKVKQKGRKFYQDENDCWFGGPNTVQKRKCSNCQQIGHDRRTCPRLQ

(XP_062517426.1) DNA topoisomerase 3-beta-1-like [Corticium candelabrum]

18

MKVVLMVAEKPSLASSIAKILSRGTMQSRKSASTACQVHEFVGPFRGEPSVRFKMTSVCGHVMSLDFQGRYNNWEAVEPGELFGAPTIRKEANPNLHIEKFLQLEGRGVDYLVLWLDCDKEGENICFEVINAVQSGMKSHSRGEQTIYRAHFSSITERDINQAMKQLGSPNHNEARSVDARQELDLRIGCAFTRFQTKFFQGKYGDLDSSVISYGPCQTPTLGFCVDRHDKIQSFKPESYWQLHVQIRCDSQLVSLEWERGRIFDKEVVQVFMALVKQTTTAKVLSVQQKEKSKSRPLPLNTVEMLRVASSGLNIGPQHTMQLAERLYTQGYISYPRTETTHFAENFDIRGTLKEHVRHPSWGGVVNSLLGGNMQKPKKGHDAGDHPPITPTRCATESEIGGGDAWRLYQYITQHFIATVSPDCSYIQTTAQFDINGEQFSCSGKRVTDPGYTALLTWQAVLDSDKMPALTKGQTHEVTDVKIVDKQTSPPAFLTESELISLMEKHGIGTDASISVHINNICERNYVRVEAGRQLIPTSLGIVLVHGYQKIDPDLVLPTMRSAVEQQLNLIAAGNADYDSVLSHALGIFTHKYEYFVQHVNSMDELFEVSFSKLADTGRPMSRCGLCRHFMKFVQAKPSRLYCQHCDTVYALPQNGTIKLYKELKCPLDDFELVLWSTGAKGKSTPVCPYCYNHPPFNDMKKGMSCGECSHPTCPHALSQSKVCSCLECDQGFLLLDMTSGPKWKMACNRCNVLVHFFENASRVSTVRESCPDCGTVYLEAAFKAPSPLASGELECRGCVFCDAALSSLVQVHHAVAQHPMYHRRRGRGRGRGRRGGRGRGRGGRGPKDKMAQLDAYFV

(XP_065835336.1) DNA topoisomerase 3-beta-1-like [Oscarella lobularis]

18

MKSVLMVAEKPSLATSIAKILSHGNFKSRKSACPACQVHEYAGRFNRSEAFFKMTSVCGHVFSLDFQSRYNNWDAVDPIELFDAETEKKEANPKLHMVKFLQQEARGVDYLVLWLDCDKEGENICYEVIDSVGSFMKHTSGSQNVFRAKFSAITDKDIRQAMETLGTPNFNEARSVDARQELDLRIGCAFTRFQTRYFQGKYGDLDSSIISYGPCQTPTLGFCVERHDQIQSFKPESYWLVAVKVSVGSFGSQTVSLEWDRVRLFDREAVQMFVSRVKESKTAKVLSVQQKEKTKARPIALNTVEMLRTASSGLGIGPQHTMMLAERLYVQGYISYPRTETTHYPENFDLKGALRQLSGQSSWAPTVKDLLSGNMQTPKKGHDAGDHPPITPLRAATETELGGDAWRLYRYIVDHFIATLSRDCRYVMTTATVDVNGELFSCSGKSVTEPGYTAVMTWQAIPSDERMPDVKKGDTLNVADVKLVERQTSPPDYLTESELITLMEKHGIGTDASIPVHINNICERNYVSIASGRRLIPTTLGIVLVHGYQKIDPDLVLPTMRSAVEEQLNLICHGKADFDSVLRHTLDIFTRKFRYFVEYVTSLDELFEVSFTKLSETGKPLSKCGICRHYMKLVTAKPTRLHCKTCDKTYRLPQNGAIKLYKELKCPLDEFELVLWTTGTRGKTAPVCPNCYNYPPFPAMSKDSTCSMCTHPTCKHSMTAHKVGACWECPSGDLVLDPTSGPKWKIACNKCNVLIHLCENAFRVSKSSTPCDECSSFYLVDVDFNKTNTPLSGGETRYQGCIFCDPVLNPLVQLHHAARQHPMYHRGRGRGRRRGRGRGHRGP

(XP_065846647.1) DNA topoisomerase 3-alpha-like [Oscarella lobularis]

15

MSGWKRILNVAEKNDAAKEISTILSRGSLRRRDGRSVYNKIYEFSYNIFGANCQMLMTSVSGHLLDIEFGPLNRKWYSCPPAALFTAAIQRICPQNFVAIKETLQELAPQCQVLILWTDCDREGEGIGFEIQEVCCAANPHLDIYRARFSEITGHSIHGASQNLGRLDRRIVDAVETRRELDLRIGAAFTRFQTMRLCKVFPADLADQLISYGSCQFPTLGFVVERHKQIENFISETFHKIKVTYQTNEGLTEFNWKRGRLFLQIACEVLHDRCMENSLATVVAKTSKHKSKWRPLPLDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPLTLNLNEIIGKQTNDPNWGAFAAGILQQGGATPRRGSKTDNAHPPIHPTKYSAGLQGNEGRVYEFVVRHFLACCSKDAQGEETTVEIDIASERFTASGLSITVRNYLDVYPYDKWSEKTLPVFQQGQTFQPTSIEMIQGETSPPSLLHEADLIALMEKHGIGTDATHADHIETIKQRGYVGLLPDGGFVPGGLGMGLVDGYDSMGLQMSKPNLRAELEADLKSICEGRKQKRDVLDAMIAKYKDLFVRATAQCLKLDEALSEYFGDPQSVAENEGFAREHPVVRKCPSCKEADMTLRTKKDGGGFIIGCGHFPNCRASIFLPSSITRATVTEESCTQCQPGPVFKLRLTCRRGTLMDQYMQEDGTYLCCVFGCDESIRVALDIRTNLLRPRDSAPSLPTPSNRSTFSSSGYNSGTSSSSSSRQRRPPGGASGFRSEGNSGYSSASFASVAGSSQNLPVNCSCNVEAVRRTVRKDGPNCGREFFCCSKPQNSRCDFFLWADNAATTAPSHPPPPPPPPPPQSSNQVSCRCGQEAVKRTVRKQGPNCGREFFCCSKPQNSRCDFFLWVDDAAEASSGPMRQATQPFSSNPTTSVSCSCGQEAVRRTVRKEGPNCGRDFFGCSKPQGSSCNFFLWCDDAASSGGHQAPQIRQSNAPSNPGQVSCSCGNAAAKRTVRKTGPNQGREFFCCMTSPNGCDFFLWVDDAQDAGGGQTGRGGESFGSRGRGRDEGGRKRKCGNCHQYGHTRRKCPNI

Name	Porifera
Rank	phylum
Topoisomerases	14

Lineage	Eukaryota > Opisthokonta > Metazoa > Porifera
Sub-taxa

Taxon : Porifera