Selection 1

Selection 2

Selection 3

All selections

Taxon : Sphingobacteriia

Informations

Name	Sphingobacteriia
Rank	class
# topoisomerases	14

Lineage and sub-taxa

Lineage	Bacteria > Bacteroidetes/Chlorobi group > Bacteroidetes > Sphingobacteriia
Sub-taxa

Topoisomerases

Select all	Name	Family	Sequence
	(1387) DNA topoisomerase type IA central domain protein [Pedobacter heparinus DSM 2366]	7	MKIVIAEKPSVGRELAKVFGATTKKDGYIEGKGYSFTWAFGHLLQLAPPQEYGFIGWRRQHLPMLPKKFKLAIRKIKTKDGMVEDPGVRKQLDIIKKLFDEATEIIVATDAGREGELIFRYIYYFLKCKKPFRRLWISSQTDEAIKEGFRNLKPGTDYDTLFNSAHCRSESDWLVGMNATQALSISAGNRSVLSLGRVQTPTLAMICSRFLEIKNFVPQTYYQLAIQLDKDGQLFRAMSVSNFDKKEEAEELLAKIEDVASGFSNGGKILSVEAKPRKEPPPLLHDLSSLQQEANKRKGFTADQTLSLLQGLYESKLVTYPRTGSRYIGDDIFAGVPALIDKVRGHKDFGKQAEFLLTVPLNKRSVNAKKVTDHHAILPTGESPYQLNGDKQAVYDMVVGRMIEAFHQECVKEITKISVESGSLFIANGTVIRAAGWRSVFNESDEEKKDEDNPALPKLKKGEELPVTNKALLEKQTKPKAMYNEASLLKALETSGKDIEDEELRYAMKDSGLGTPATRAAIIETLISREYVSREKRNLVPTTKGLAVYDVVKDQKIAQAELTGQWEKRLEEIRSGASVSDFKAEIADYTKTITNELLAAGLTLAEKI
	(2) DNA topoisomerase 1 [Pedobacter heparinus DSM 2366]	1	MAKNLLIVESPAKAKTIEGYLGKDFLVKSSYGHIRDLVKGDMAIDTANNFAQTYEVPSDKKQVVAELKKLAKDAEMVWLASDEDREGEAISWHLYETLGLKENKTKRIVFHEITKPAILKAIETPRSIDYNLVNAQQARRVLDRLVGFELSPVLWKKIKPSLSAGRVQSVAVRLIVDREREVNKFNAAAAFKITAEFVTGNGKELVKAELPQRFEKEADAEKFLNDCAGAGFSVDSLETKPAKRNPAAPFTTSTLQQEASRKLGYSVSRTMQIAQRLYESGRITYMRTDSVNLSETALQAAASEIRSAWGDKYHQPRTYKTKSAGAQEAHEAIRPTYFNQHTVPGDSSEQRLYELIWKRAIASQMSEALFEKTTAQIGISTRKEQLIAEGEVLKFDGFLKVYLESSDEEDAEDSEGNNMLPALSRGQALTLKVMNATERFSRPPARYTEASLVKKLEELGIGRPSTYAPTISTIQNRGYVVKEDRDGRQRSFAAIELSNGSVTKKTKTEITGAEKGKLFPTDIGEVVNDFLVEHFKGIVDFNFTANVEKEFDEIAQGLQEWTKMLHSFYTPFHLEVENTLETADRANGERLLGLDPATGKNVYTKVGRFGPLVQIGENDDEEKPRYASLSKSQSVGTVTLEEALEQFKLPFSLEDYQGKEVSVGVGRFGPYVKWGDAFISVPKNEDPLSIDQARAIEIIGEKITADAPVAHYQGMPVTKGTGRFGPFIKWNDLFINVPKAYNFDRLSQQDIEELIGKKIEKEANRFIQQWPAEKIAIENGRWGPFIRFGKEMLKLRKNPATNDKYTPEELASIALDEVKKLIVEQVPNAFEPKKKAAAKKTGAAKKAPAKKKAVAKK
	(1571) DNA topoisomerase [Pedobacter saltans DSM 12145]	7	MKVVIAEKPSVGRELAKVFGATTRKDGYIEGKGYTFTWAFGHLLQLAPPQEYGFYGWRKENLPMLPQKFKLSIRKIKTKDGVVEDPAVKKQLDTIKRLFDECDEIIVATDAGREGELIFRYIYYYLKCKKPFRRLWISSQTDEAIKNGFRNLKPGTEYDTLFNSAHARSQSDWLVGMNATQALSISAGNKSVLSLGRVQTPTLAMICARFLEIKNFVPKIYYQVAIQLCKDEQFFKAISTKNFDTKEEAEEVLAKVLDVESGSPTGGHIKNVEGKAKKEPPPLLHDLSSLQQEANKKKGYTADQTLGILQNLYESKLVTYPRTGSRYIGDDIFATVPDLISKYKNHGLFGKSAEYLLENKLNKRSVNAKKVTDHHAVLPTGIDPGYLPEDKQAVYDMVVGRMLEAFHQDCIKETTKISIESGSDFVANGTVIKIAGWRSVFNDPDDEKKDASENATLPKVDKGENLPVTKKAVVEKQTKPKPQYTEATLLKALETCGKDIEDEELRYAMKDSGLGTPATRAAIIETLITREYISREKKNLIPTSKGLAIYEVVKEKKIAQAELTGQWEKRLEEIRGGASVLDFKNEIIDYTRNITQELLAAGIGLEKVLVTG
	(35) DNA topoisomerase III [Pedobacter saltans DSM 12145]	7	MKAIIAEKPSVAREIATLLGATEKRDGYLTGNGYEVTWALGHLVGLAMPEDYGVSGFQREALPILPNPFLLTVRKIKKDKSYVPDNGALKQLNIIEQVIGRCDSIIVATDAGREGELIFRYIYEYLKCRKPFERLWISSLTEKAIKQGFDNLKAGSDFDGLYRAGQGRSKADWLVGINASQALSISAGRGVYSLGRVQTPTLALICKRYLENKDFAVKKYFQIQLEHRKEFTDFKSLSKTKWDDRKLADDTLKSIQRNGTATVTAMETKTVTEQPPLLFDLTGLQKEANKRASYTAEETLNIAQSLYEKKFITYPRTGSKYIPEDMWSEIPALVRNLEARASCKKAVGKVKWGRFNKRIVNDVKVTDHHGLLITEKIPSELTAHENVIYDMIAYRLLEALSSACTKEITDIGLQAFHYDFTLKGCKIIEAGWRGIKGKFTDEDSDPVQELPELKVGDELKIKVASVLEKITKPPVLYTEAGLLSAMENAGKEIDNEDERKALKDIGIGTPATRASIIETLFKRDYIRREKKSLIPTHKGLQVYGAVKDKKIADVAMTAEWEMALQKIENNDANADAFHRDMETYATFITRELLDTGIAKEKQPELTCPKCKSRQLLVWNKVVKCPDEACGWLQFRIVCGVPLSVADIESLVTKGKTNLIKGMKSNSGNKFNAYIVMNDKAETSFEFENRKPKRK
	(1349) DNA topoisomerase III [Pedobacter saltans DSM 12145]	7	MKTIIAEKPSVAREIAGLVGASDKKDGYLTGNGYFVTWAFGHLIGLGMPEDYGISGFDKASLPILPNPFLLTVRKVKKDKGYTADTGALKQLKVIEQLFKQSNSIIVATDAGREGELIFRYIYEYLKCNKPFERLWISSLTEKAIKQGFNNLKDGAAFDGLYQAAQGRSRADWLVGINATQALSIAAGNGIYSLGRVQTPTLALICKRYLDNKNFTVKKYWQIQLTHNKAQVDFKSISATKWDEKQLADDTLKAIQRGATATFTSVETKSVTEQPPLLFDLTGLQKEANKRLKLSAEATLNIAQSLYEKKFITYPRTGSKYIPEDMWAEIPNLVRALQNREDCKQALTKIKWGRFNKRIVNDLRVTDHHGLLITDKVPSVLNADENKIYNMIALRLLEAISQACVKEITDVSLQVLHYDFTAKGCKIQEAGWRSIKGSFTDDGEEPVQELPELHKGDELAIKEAAVLEKQTKPPVLYTEAGLLSAMETAGKEIENEEERKALKNIGIGTPATRAAIIETLFTRNYIQRDKRSLIPTEKGLQVYGLVKDRKIADVAMTAEWELALQKIENNEADAGTFQKEMETYAKSITDELLQTSIASTNQPKLTCPKCKSQQLIIRDKIVKCPDEACNWVQFRTVCGVQISIENVTNLVNKGKTSLIKGMTSKAGKKFDAYIILKENAESSFEFEKNKSSKRNGK
	(1102) DNA topoisomerase 1 [Pedobacter saltans DSM 12145]	1	MAKNLLIVESPAKAKTIEGYLGKDFLVKSSYGHIRDLRKDDGAIEVDNNFKQHYEIPADKKQVVAELKKLAKSAETVWLASDEDREGEAIAWHLYESLGLKENQTKRIVFHEITKPAITKAIENPRTIDYNLVNAQQARRVLDRLVGFELSPVLWKKVKPSLSAGRVQSVAVRLIVEREREINLFNAESAYKIIAIFSTGKGKEIFKAELSQRYAEQKEAEKFLEDCKSALYKINDLDIRPTKRTPAPPFTTSTLQQEAGRKLGFSVSRTMSIAQRLYETGKITYMRTDSVNLSETALNASEIEINSAYGSKYHHKRIFKTKSAGAQEAHEAIRPTHFEWHTIEGDASEKRLYELIWKRAIASQMSEAQFEKTTARIGISTRKEELVANGEVLKFDGFLKVYLESEDEESDSHLDDKTDNGILPPLNIGQELILNEMTALERFTRPAARYSEASLVKKLEELGIGRPSTYAPTISTIQNRGYVVKEDRDGRSRTYKTFTLKDGEVKSIVKSEITGTEKGKLFPTDIGAVVNDFLVEHFKGIVDYNFTATVEKQFDEIANGLKEWTDMLKKFYQPFHSEVEDTLKNADRATGERLLGLDPESGKNVYTKVGRFGPMVQIGEMDEEDKPRYASLLKSQSVETISLEEALNLFQLPFQLSDYKDKEVSVGVGRFGPYVKWGDTFISLPKNEDPLTVTNERAIEIIEEKISIDAPVAEYQGHPVSKGKGRFGPFLKWKDLFINVPVRYNFDKLSQSDINELISAKIEKEANRYIQQWETEKIAIENGRWGPFIRFGKQMLKLGKNPTTGQKYTAEELSTVSLEDVKKLIVEQVPDAFDAKAKKTGRKTTKK
	(331) DNA topoisomerase III [Niastella koreensis GR20-10]	7	MKVCIAEKPSVARDIAAVIGAKQKKDGYLEGNGYQVTWTFGHFCTLKEPHDYTDQWKYWRLEDLPMIPPNFGIKLIPNDGVQKQFKVIEQLVQNCEEVINCGDAGQEGELIQRWVLLKAQCNAPVKRLWISSLTEDAIREGFKKLKDSNQYDNLYAAGSARAIGDWLLGMNATRLFTKKFAQGKAVLSIGRVQTPTLAMIVARQKEINAFVSEEYWELKTIYREVEFTAAIDRIKVLDRAEKGLAYLKEHPFEITSFERKDGKEGNPRLFDLTALQVEANKKFAYSADDTLKYVQNLYEKKMVTYPRVDTTYLSEDLHPKIEGILRDLTPYAALTASILANPIPKLKTVFDDKKVTDHHAIIPTGVYPSNLPAEEKRIYDLIARRFIAAFYPECKISNTTVLGKVGQVPFKVTGKQILEPGWREVYANDVKTEKEKEEEEEKVLPVFVVGESGPHTPRIHKGKTSPPKAYTEATLLRAMETAGKQVDDEEMRELMKDNGIGRPSTRANIIETLFRRKYIEKKKKNIYATQTGIDLIDTIQTELLKSPELTGIWERKLRLIEKGEYPKDTFKQELIQMVIDLTAEVKTATYRAITVVEQQPAKKEKDTPDKPKKEAKPKEPKKAVAIEEQQCPKCKSHPLKKGNTAYGCANFKVCGFKVPFEVFGKKLTDKQIADLLTRGKTGKAKGWVVAGAEKEGKLRFSDAFDLEIE
	(1494) DNA topoisomerase 1 [Niastella koreensis GR20-10]	1	MAKNLLIVESPAKAKTIEKILGKDFEVKSCFGHIRDLEKEEMGIDIKNGYQPRYKVPADKERVVKELKSLANKSDEVWLATDEDREGEAISWHLCEVLGLDPSTTKRIVFHEITKPAIQKAVTSPRLLDMNLVNAQQARRVLDRIVGFELSPVLWRKISARGSNLSAGRVQSVAVRLIAEREREINAFQATSTFKIEALFTTPDITGKNVTFVAEGKKYDTAENAEKFLQTCIGAKYKVNDIQVKPGKKSPAAPFTTSTLQQEASRKLGYGVKRTMTLAQRLYESGNITYMRTDSVNLSDTAMAEIRKQVTGQYGNNYYQPRKYKNKNESAQEAHEAIRPTYMENSTIDDPDCKRLYELIWKRTMASQMADAELEKTIAKIEISTNKEELTASGEVLKFDGFLKVYREDRDEEDITDDEQQEGMLPPLTVNQQLPLNEMKAIERFSRPSPRYTEASLVKKLEELGIGRPSTYAPTINTIQERKYIEKRDKEAVKRNFRILTLKEDKISKVTEQENTGAEKSKLFPSDLGLVVTDFLKQYFDDIMDYGFTARIENEFDEVAAGKLKWNNMIDDFYLPFKKDVDNTIETAERAKGERELGIDPQSGKKITARIGRFGPMVQIGDANEEEKPRFAGLRRGQSIETITLEEALKLFELPKTLGEHEGQEIVVNMGPFGPYIKFGEQNISMPRGIDPNDVNMEKALEFIADKQKADAPIAHYDNKPVTKGTGRFGPFIKWNNMYINVPKKGYDFENLTQDDIDKLIEGKIKKEENRYIQNWPDEKISIENARWGPVLKFGKKILKVGRKADDTKYTAEELVSVPLDDVKKMIEAQVPNAFASKKAAAKKAPGKKAAPKKDATKKKAAPKKK
	(457) DNA topoisomerase 1 [Haliscomenobacter hydrossis DSM 1100]	1	MSKNLLIVESPAKAKTIEKFLGKDFAVRSSYGHVRDLDKGNQAVDVKNGFSPKYTISPEKHKVVKELKDWVKKVDEVWLATDEDREGEAISWHLCEVLGLDPKSTKRIVFREITKPAIEKAVQQPRTVDLNLVNAQQARRVLDRLVGFELSEILWKKVKGKLSAGRVQSVAVKLVVEKEREINSFKSEAYFKIEALFDVKNEQGRTVSLKAEGTDRIKTEMDAETFLKKCIGAAYKIQSIDVKPLKRRPTAPFTTSTIQQEASRKLGFSVNRTMVTAQKLYEAGFITYMRTDSINLSETAIASISQEIEKLFGKKYVEVRRFKGKSANAQEAHEAIRPTYIENQTVPGDRDEKRLYELIWKRTIASQMADAELEKTVVDIGISTQPGVSLQAEGEVLKFDGFLKVYLESNDDDEEDEAQGVLPPLKVGQVLPFNQMKATERFTRPPSRYSEAGLVKKLEELGIGRPSTYAPTISKIMEEGRGYVVKENRDGAPRAFRELTLKDAQISKKELSEMTGVIKGRLFPTDMGSTVSDFLDQHFDKIMDYKFTAEIEKLFDDIAAGSREWTEMLGTFYWPFHEIVEETMANADRPTRERILGKEEGTGYSVLTRMTRLGPVVQIGTPEELIPGEKPRYANLKPGQSIETIEMEEAMKLFELPKILGDYRSQEVAVGTGRYGPYVRFGEKFISIPKGEDPLSVTLERALELIEEREKVDAPVASYKGFPITKGTGRFGPFIKWNDTFINVPKKYNLETLTPEEMHELIEGKMEKEANRYIQNWPDEKISIENGRWGPFIRFKKDMLKLPRLDGQKMSPEDAALLSLEDVKKTIEEQVPDAFAKKAPVKKAPAKKAAPKAAAAKGAKVKK
	(153) DNA topoisomerase [Sphingobacterium sp. 21]	7	MKIIITEKPSVARDLAKVFGATTKRDGYIEGKGYSFTWAFGHLLQLAPPQEYGYIGWKVKNLPMLPQKLKLSVRKIRTNEGMIEDPSVRKQLNTIKALFDIATEIIVATDAGREGELIFRYIYHYLHCQKPFRRLWISSQTDAAIKDGFRNLKPGKDYDTLFYSAHCRSESDWLVGMNATQALSISAGSKTVLSLGRVQTPTLAMICARYLENKNFIPQTYFQVIISLQKDGQNFKAVSKKNYYKREEAEEILNAVKSVADGFATGGDISKVETKTKKEQPPLLHDLSSLQQEANKKKGYTADETLAILQRLYEEKLITYPRTGSQYIGDDVFETIPQLIEKQQQHPFFSKQAIVLANNKLNKRSVNAKKVTDHHAILPTGEPARNLSPDKQVLYDMIIGRMLEAFHEVCVKDLTKITIESGSTFIANGTVIRSAGWRAVYNEPEENDQDQPENNTIPKVSEGESLAIIEKSIAEKQTKPKPLYTEASLLKAMETAGKEIENEELRYAMKGSGLGTPATRASIIETLIKRSYITRKKKNLLPSETGLAVYDIVKDKLIAQAELTGQWEKRLEEIRSGASVKAFKEEIKQYTRKITEELLIAGKELELLLEDQG
	(1224) DNA topoisomerase III [Sphingobacterium sp. 21]	7	MKAIIAEKPSVAREIAALLGATEKRDGYQTGNGYQVTWALGHLVGLAMPEDYGVSGFQREALPILPDPFILTVRKVKKNKSYVPDSGALKQLKVIEQVIGRCDSIIVATDAGREGELIFRYIYEYLKCRKPFERLWISSLTEKAIKQGFDNLKAGNEFDGLYRAGQGRSKADWLVGINASQALSISAGRGVYSLGRVQTPTLALICKRYLENKDFVVKKYFQIQLEHRKEFTDFKSLSKTKWDDRKLADDTLKSVQRNGTATVTAVETKTVTEQPPLLFDLTGLQKEANKRAFYTAEETLNIAQSLYEKKFITYPRTGSKYIPEDIWPEIPALVRNLEARASCKKVVGKVKWGRFNKRIVNDVKVTDHHGLLITEKIPSELSAHENVIYDMIAHRLLEALSPTCTKEITDIRLQALHYDFTLKGCKILEAGWRGIKEKFIDEDSEPVQELPELKVGDELKIKKASVVEKKTKPPVLYTEAGLLSAMENAGKETHNEEERKALKDIGIGTPATRASIIETLFKRDYIRREKKSLIPTDKGLQVYSVVKDKKIADVAMTAEWEMALQKIENNEADADAFHRDMEAYATSITRELLDTGIAKEKHPALTCPKCKSRQLLMWHKVVKCPDEACGWLQFRTVCGVPLSLADIESLVSKGKTNLIKGMKSKSGNKFDAYIIMDDTGKVSFEFEKRKPKRK
	(174) DNA topoisomerase 1 [Sphingobacterium sp. 21]	1	MAKNLLIVESPAKAKTIEGYLGKDFLVKSSYGHIRDLVKTDDAIDTANNFEQKYEVPADKKAVVSELKKLAKSAETVWLASDEDREGEAISWHLYETLNLKESSTKRIVFHEITKPAILKAIEQPRKIDFNLVNAQQARRVLDRLVGFELSPVLWKKVKPSLSAGRVQSVAVRLLVDREREINKFEPEAAFRVVAIFFTEENKKELFKAELSKRFATINEAEKFLNDCIPASYHVKSLETKPSKRNPAAPFTTSTLQQEASRKLGFSVARTMTVAQRLYESGKITYMRTDSVNLSDTALQAAEQEIRSAYGDKYHKRRQYKTKSAGAQEAHEAIRPTYFNQHTIEGDHSEKRLYELIWKRAIASQMSEAEFEKTTAKINISTRNEEFTASGEVMKFDGFLKVYFESTDEESEVNLEESDDNALLPPLRNGQQLGLKEMTATERFSRPPARYTEASLVKKLEELGIGRPSTYAPTISTIQNRGYVVKEDREGKQREYNVLTLGHGKVNTTKKTEITGAEKSKLFPTDIGILVNDFLVEHFKDIVDFNFTATVEKEFDEIANGLKEWTAMLHNFYGPFHKEVTDTIENADRASSERILGTDPQTGKQVSVRIGRFGPLVQIGSADDEEKPVFASLRSGQMIETISLEEALELFKLPKKVGKYEDKEMTVAIGRFGPYIRHNNAFYSLPKGIDPMDVNETQAIEIIELKRKKDIEKVIKTFDENPEARIEQGRWGPFIRFGKQNIKIPKDKDVDKITYNDILQLAESDKSNTGTKKKVPAKGKSKTAKKK
	(1323) DNA topoisomerase 1 [Chitinophaga pinensis DSM 2588]	1	MAKNLVIVESPAKAKTIEKILGKDFEVKSCFGHIRDLEKDDMGIDIANNFKPKYTIPDDKEKIVKELKKLAKDTDEVWLATDEDREGEAISWHLCEVLGLDPDVTKRIVFHEITKPAIERAVQQPRLLDMNLVNAQQARRILDRIVGFELSPVLWRKMSMRNSLSAGRVQSVAVRLIVEREREINTFNAVSSFKVEAFFTAKDLQGKNITFKAEGPTRFKTAEDAEKFLQQCIGAAYSVKDIQVKPGKKSPAAPFTTSTLQQEASRKLGYSVSKTMLLAQKLYESGKITYMRTDSVNLSDTALGDIQNAITTNYGQRYHQHRKFKNKNESAQEAHEAIRPTYMENATVDDSDTKKLYELIWKRTIASQMSDAELEKTIAKIDISTNHEELTASGEVLKFDGFLKIYMEGKDDEDVSDEEESDGSLPALTVKQALDLKEMKATERYSRPAPRYTEASLVKKLEELGIGRPSTYAPTITTVQKRGYVEKRDKEGIKRDFRILSLKADKITKVTESENTGAEKSKLFPTDLGMIVTDFLNQYFSSVMDYGFTAKIEGEFDEVAHGKKIWNKMLNDFYTPFHKDVENTLEKAERVKGERQLGTDQETGKPIVARMGRYGPMIQIGKAEDEEKPKFAKMKSTQSIETITLEEAMELFRLPRNLGQFEDQDVLVNIGRFGPYAAHNKQFYSLKKEMDPYTVELDEIAPLIVEKRTAKDERTIKIFEKEKIQILKGPYGPYIKQGLRNYKIPKEKIDAAADITLEEAKAIIEDVKANPPKKKAPPRKKKAE
	(1838) DNA topoisomerase III [Chitinophaga pinensis DSM 2588]	7	MKVCIAEKPSVARDIAEVIGAKERKDGYYEGNGYQVTWTFGHFCTLKEPHDYTEQWKFWRLEDLPMIPSSFGIKLIDNSGVQKQFKIIEQLVQHSEEVINCGDAGQEGELIQRWVLLKAQCTAPVKRLWISSLTEQAIREGFQKLKDADQYNNLYAAGSARAIGDWLLGMNATRLFTKKFAMGKTVLSIGRVQTPTLAMIVARQKEINAFVSEEYWELKTVYREVEFTATIDRIKVLDRAEKGLAYLKEHPFEVTSFEKKEGKEGNPKLFDLTALQVEANKKYAYSADDTLKYIQNLYEKKLVTYPRVDTTYLSEDLHPKIAGIMQDLTPYAALTAPILANPIPKLKTVFDDKKVTDHHAIIPTGIYPSNLGMEEKRIYDLVARRFIAAFYPECKISNTTILGKVGQVEFKVTGKQILEPGWKEVYANDVTPKKEGEEEEKILPVFEVGESGPHTPRIHQGRTTPPKAFTEATLLRAMETAGKQVDDEEMRELLKDNGIGRPSTRANIIETLFRRKYIEKRKKNIFATQTGIDLIDTIQTELLKSPELTGIWEGKLRQIEKGEYAMETFKQELIQMVIDLTIEVKTSNYKVITVRPDQPEEKEKEKEEKPKKEAKPKEPKKAVVIAEQQCPKCKAHPLKKGNTAYGCANFNVCGFKVPFEVFGKKLTDKQIADLLAKGKTGKIKGWKLPGAAGDTEGKLILNKGFELEVEKA

Family distribution

Taxonomy tree

Sphingobacteriia