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Taxon : Mycobacteriaceae
Informations
Name
Mycobacteriaceae
Rank
family
# topoisomerases
20
Lineage and sub-taxa
Lineage
Bacteria
>
Actinobacteria
>
Actinobacteria
>
Actinobacteridae
>
Actinomycetales
>
Corynebacterineae
>
Mycobacteriaceae
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(479) DNA topoisomerase 1 [Mycobacterium avium 104]
8
MADPKLKENTSGGNGSRRRLVIVESPTKARKLASYLGSRYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPEKKHTVSELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPNIPVKRMVFHEITEPAILEAAENPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSASYWDIVAQLDASVSDPQASPPTFAARLTSVDGLRVATGRDFDSQGQLRKADEVIVLDEPQATELAAGLQGAQLSVASVEEKPYTRRPYAPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSGSAINAARTQARQLYGEEYVSPSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGDEFRLYELIWQRTVASQMADARGTTLSLRIGGQAGDRQVVFSASGRTITFPGFLKAYVETVDELAGGEADDAESRLPQLTQGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDAIASGQERRTDWLNNFYFGGEHGVADSIARSGGLKKLVGVNLEGIDAREVNSIKLFDDEQGRPVYVRVGKNGPYLERMVTGDDGEPTPQRANLNDSLTPDELTLEVAEQLFATPQEGRVLGVDPATGHEIVAKDGRYGPYVAEVLPEPPPDDDDGSGAPAKKGKKPTGPKPRTASLLRTMDLQTVTLEDALRLLSLPRVVGVDPETGEEITAQNGRYGPYLKRGNDSRSLATEEQLFDITLEEALKIYAEPKRRGRQGAAAPPLRELGADPATGKPMVIKDGRFGPYVTDGETNASLRKGDDVMSLTDQRAAELLADRRARGPAKRTAKKTSRKAPAKKAAKRG
(1086) DNA topoisomerase 1 [Mycobacterium gilvum PYR-GCK]
8
MADGDRGSGKNGSVRRLVIVESPTKARKIAGYLGSNYVVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPDKKATVADLKDKLKNVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEDPRDLDNDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFRSAGYWDVTAELDASVSDAQATPPTFVAKLNTVDGRRVAAGRDFDSLGAVKKPGEVLVLDEAAANALAGGLRGAQLSVSSVEQKPYTRRPYAPFMTSTLQQEAGRKLRMSSERTMSIAQRLYENGYITYMRTDSTTLSQSAIDAARNQARQLYGEEYVHPTPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHSQLDTDEFRLYELIWQRTVASQMADARGTTLSLRIAGAATSGEQVVFNASGRTITFAGFLKAYVESLDEQAGGEADDAESRLPNLTQGQRVDAKDLTADGHTTSPPARYTEASLIKALEDLGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVIGLLEQHFSRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGEHGVEGSIAREGGLKKLVGGNLEEIDAREVNSIKLFDDSEGRAVNVRVGRNGAYLERMVADPDNPGELKPQRANLKDELTPDELTLELAEKLFATPQEGRSLGIDPATGHEIVAKDGRYGPYVTEVLPEPPDDGEAGATAKKGKKPTGPKPRTGSLLRSMDLETVTLDDALRLLSLPRVVGVDPANGEEITAQNGRYGPYLKRGTDSRSLATEEQMFDITLEEALKIYAEPKRRGRQGAATPPLRELGVDPVSEKPMVIKDGRFGPYVTDGETNASLRKGDDVMSITDARASELLADRRARGPVKKKAAKKAAVKKTAAKKAAKKAPAKKAAKKA
(208) DNA topoisomerase 1 [Mycobacterium sp. MCS]
8
MKNWSRIQLADGSPRGGNGGGEPPARRANGSVRRLVIVESPTKARKIAGYLGSNYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVDVEHDFEPLYIISPDKKSTVADLKDKLKNVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEDPRDLDNDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFRTAGYWDVSAELDASVSDPQATPPTFTAKLNSVDGRRVATGRDFDSLGQVRKPDEVLVLDEAAAGALAAGLQAAQLSVSSVEQKPYTRRPYAPFMTSTLQQEAGRKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSQSAIDAARNQARQLYGEEYVHPTARQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHAQLDTDEFRLYELIWQRTVASQMADARGTTLSLRIAGDSRDGQSVVFSASGRTITFAGFLKAYVESIDELAGGESDDAESRLPNLTQGQRVDAKELTPAGHQTSPPARYTEASLIKALEDLGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVIGLLEQHFGRLVDYGFTAAMEDELDEIASGTERRTNWLKNFYFGGEHGVGDSIARAGGLKKLVGVNLEEIDAREVNSIKLFDDAEGRPIYVRVGKNGPYLERMVADEENPGELKPQRANLKDELTPDELTLELAEKLFSTPQEGRTLGVDPETGHEIVAKDGRYGPYVTEVLPAPPEEPEDGAPAKKGKKPTGPKPRTGSLLRTMDLETVTLDDALKLLSLPRVVGVDPNTGEEITAQNGRYGPYLKRGTDSRSLATEEQMFTITLDEALKIYAEPKRRGRQGAATPPLRELGVDPVSEKPMVIKDGRFGPYVTDGETNASLRKGDDVMSITDARASELLADRRARGPVKKKAAAKKAPAKKTAAKKTAAKKASAKKA
(1014) DNA topoisomerase 1 [Mycobacterium abscessus ATCC 19977]
8
MRRLVIVESPTKARKIAGYLGDGYVVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIVSPDKKGTVTELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPKVPVRRMVFHEITEQAILAAAQDPRDLDNNLVDAQETRRILDRLYGYEVSPVLWKKVGRNLSAGRVQSVATRIIVQRERDRMAFRSAGYWDLGAELDAGKDNPAAKPPRFHARLVSVDALRVASGRDFDSLGQVKETSNGPGVLVLDETRANALVAGLSQATLTVVSAEEKPYTRKPYPPFMTSTLQQEAGRKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSDSALQAARSQAAELYGNEYVHPSPRQYTRKVKNAQEAHEAIRPAGETFKTPGQLHSSLDNDEFRLYELIWQRTVASQMADARGTTLSLRLAGTATSGEQVVFTASGRTITFPGFLSAYVETVDELSGGEADDEERRLPQLRQGQSVTVAELSADGHTTNPPARYTEASLIKALEELGIGRPSTYSSIIRTIQDRGYVHKRGSALVPSWTAFAVIGLLEQHFGRLVDYDFTAAMEDDLDEIASGNERRTNWLNAFYFGGDHGVEGSVARAGGLKRLVGVNLEEIDAREINSIKLFDDDQGRPIYVRVGKNGPYLERMVADPDGEAGALIPQRANVKDGVTPDELTVEMAEQLFAIPQEGRTLGVDPETGHEIVAKDGRFGPYVTEVLPAPPEPVEAEKPKRGAKKVEGPKPRTGSLLKSMTLETVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGTDSRSLATEGQIFTVTLDEALKIYSEPKRRGGQAASAAPLRELGVDSATGKPMVIKDGRFGPYVTDGETNASLRKGDDVLSITDERASELLADRRARGPVKRAKKAPAKAAKKAPAKKAPAKKAAKKAT
(1075) DNA topoisomerase 1 [Mycobacterium ulcerans Agy99]
8
MADPKTKGPGSRSSGGNGSGRRLVIVESPTKARKLAGYLGPRYIVESSRGHIRDLPRAAADVPAKFKSEPWARLGVNVDADFEPLYIISPEKKSAVSELKDLLKDVDELYLATDGDREGEAIAWHLLETLKPRVPVKRMVFHEITEPAILEAAENPRDLDMDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRMIVQRERDRMAFRRASYWDIVATLDASVSDPKAAPPTFVARLTSVDGLRVATGRDFDSLGTLRKADEVTVLDEARAAALATGLHGAQLSVASVEEKPYSRRPYPPFMTSTLQQEAGRKLRFSGERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVASSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGDEFRLYELIWQRTVASQMADARGTTLSLWIGGSAGEQQVVFSASGRTLTFPGFLKAYVETVDELVGGEADDAERRLPNLTPGQRLDAVELTPDGHTTNPLARYTEASLVKAFEELGIGRPSTYTPIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGHLVDYGFTAAMEDELDAIASGQERRTDWLNNFYFGGDHGVSDSVARAGGLKKLVGVNLEGIDAREVNSIKLFDDEQGRPIYVRVGKNGPYLERTITGEDGEPTPQRANLNDSLTPDELTLVLAEELFATPQEGRVLGIDAESGHEIVAKDGRYGPYVTEILPEPPAPEAGTEAPAKKSKKATAPKPRSGSLLRSMDLQTITLEDALKLLSLPRVVGTDPASGEEITAQNGRYGPYLKRGTDSRSLATEDQIFSITLDEALKIYAEPKRSGRQSASAPPLRELGTDAASGKAMVIKDGRFGPYVTDGETNASLRKGDEVASITDERASELLADRRARGPVKRAAKKTTRKSPAKKAVKRA
(106) DNA topoisomerase 1 [Mycobacterium tuberculosis H37Rv]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(107) DNA topoisomerase 1 [Mycobacterium tuberculosis H37Rv]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(774) DNA topoisomerase 1 [Mycobacterium tuberculosis F11]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASMRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(1617) DNA topoisomerase 1 [Mycobacterium canettii CIPT 140010059]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(929) DNA topoisomerase 1 [Mycobacterium avium subsp. paratuberculosis K-10]
8
MADPKLKENTSGGNGSRRRLVIVESPTKARKLASYLGSRYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPEKKHTVSELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPNIPVKRMVFHEITEPAILEAAENPRDLDIDLVDAQETRRILDRLYGYEVTPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSASYWDIVAQLDASVSDPQASPPTFAARLTSVDGLRVATGRDFDSQGQLRKADEVIVLDEPQATELAAGLQGAQLSVASVEEKPYTRRPYAPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSGSAINAARTQARQLYGEEYVSPSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGDEFRLYELIWQRTVASQMADARGTTLSLRIGGQAGDRQVVFSASGRTITFAGFLKAYVETVDELAGGEADDAESRLPQLTQGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDAIASGQERRTDWLNNFYFGGEHGVADSIARSGGLKKLVGVNLEGIDAREVNSIKLFDDEQGRPVYVRVGKNGPYLERMVTGDDGEPTPQRANLNDSLTPDELTLEVAEQLFATPQEGRVLGVDPATGHEIVAKDGRYGPYVAEVLPEPPPDDDDGSGAPAKKGKKPTGPKPRTASLLRTMDLQTVTLEDALRLLSLPRVVGVDPETGEEITAQNGRYGPYLKRGNDSRSLASEEQLFDITLEEALKIYAEPKRRGRQGAAAPPLRELGADPATGKPMVIKDGRFGPYVTDGETNASLRKGDDVMSLTDQRAAELLADRRARGPAKRTAKKTSRKAPAKKAAKRG
(1200) DNA topoisomerase 1 [Mycobacterium bovis AF2122/97]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
(385) DNA topoisomerase 1 [Mycobacterium vanbaalenii PYR-1]
8
MADEERGSGKNGAEPRRGNGSSVRRLVIVESPTKARKIAGYLGSNYIVESSRGHIRDLPRNAADVPAKYKSEPWARLGVNVEHNFEPLYIISPDKKSTVADLKDKLKNVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEDPRDLDNDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFRSAGYWDVTAELDASVSDAQASPPTFVAKLNTVDGRRVATGRDFDSLGAVRKPDEVLVLDEAAANALATGLRGAQLAVSSVEQKPYTRRPYAPFMTSTLQQEAGRKLRFTSERTMSIAQRLYENGYITYMRTDSTTLSQSAIDAARNQARQLYGEEYVHPTPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHSQLDTDEFRLYELIWQRTVASQMADARGTTLSLRIAGAAPATTLGGGTASDVQVVFNASGRTITFPGFLKAYVESIDDLAGGEADDAESRLPNLTQGQRVDAKGLTADGHTTSPPARYTEASLIKALEDLGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVIGLLEQHFGRLVDYDFTAAMEDELDEIAAGHERRTNWLNNFYFGGEHGADGSIARSGGLKKLVGGNLEEIDAREVNSIKLFDDAEGRAVNVRVGRNGAYLERMVADPDNPGELKPQRANLKDELTPDELTLELAEKLFATPQEGRSLGVDPATGHEIVAKDGRYGPYVTEVLPEPPDEGEAGATAKKGKKPTGPKPRTGSLLRSMDLETVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGTDSRSLATEEQMFDITLEEALKIYAEPKRRGRQGAATPPLRELGVDPVSEKPMVIKDGRFGPYVTDGETNASLRKGDDVLSITDARASELLADRRARGPVKKKAVKKAPAKKTPAKKTAAKKAAKKA
(1065) DNA topoisomerase 1 [Mycobacterium rhodesiae NBB3]
8
MADGNVRRLVIVESPTKARKIAGYLGSNYIVESSRGHIRDLPRNAADVPAKFKSEPWARLGVNVEDDFEPLYIISPEKKSTVAELKDLLKSVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAADDPRDLDNDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVSRERERMAFRSAGYWDVTAELDASVSNAQASPPTFTAKLNSVDGRRVATGRDFDSLGGLKKPDEVLVLDQSAAGALAAGLRGAQLEVSSVEQKPYTRRPYAPFMTSTLQQEAGRKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQATQLYGQEYVHPSPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHAQLDTDEFRLYELIWQRTVASQMADARGTTLSLRISGSSSDGQQVVFSASGRTITFAGFLKAYVESIDEQAGGEADDAESRLPNLEQGQRVDAKELTADGHTTSPPARYTEASLIKALEDLGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFSRLVDYGFTAAMEDELDEIASGNERRTNWLHNFYFGGDHGVEDSIARSGGLKKLVGVNLEGIDAREVNSIKLFDDDQGRAINVRVGRNGPYLERMVPDPDNSGELKPQRANLNDELTPDELTLELAEKLFSTPQEGRSLGVDPATGHEIVAKDGRYGPYVTEVLPTPDEPDDDAGSTAKKGKKPTGPKPRTGSLLRTMDLETVTLDDALRLLSLPRVVGVDPTTNEEITAQNGRYGPYLKRGTDSRSLATEEQMFDITLDEALKIYSEPKRRGGQRAAAPPLRELGNDPATDKPMVIKDGRFGPYVTDGETNASLRKGDDVMSLTDGRAAELLADRRARGPVKKKSTKKAAKKKAPAKKAAKKA
(641) DNA topoisomerase 1 [Amycolicicoccus subflavus DQS3-9A1]
8
MAARGSGTANGSARAGDSRVVRRLVIVESPTKAKKIASYLGSGYVVESSRGHIRDLPKGAADVPAKYKGEAWARLGVNVDEDFEPLYVVSADKKATVSELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPKIPVRRMVFHEITEPAIRAAAENPRDLDSDLVDAQETRRIVDRLYGYEVSPVLWKKVMPKLSAGRVQSVATRIIVQRERERMEFTAAEYWDIAATLDAGSGVTPQTFGAKLMSVGGERVATGRDFGPNGALKSSSAVRVLDEAHAGRLAEALQGQALAVTSAEEKPYTRRPYAPFMTSTLQQEAGRKLRFSADRTMRIAQRLYENGYITYMRTDSTTLSSSAIDAARNQARELYGPEYVAPSPRQYTRKVKNAQEAHEAIRPAGETFQTPGQLHRVLEADEFRLYELIWQRTVASQMADAKGTTLSLRITGTAATGEECVFSSSGRTITFPGFLSAYVETVDEEAGGQADDEERRLPRLTEGHAVTASELRPDGHSTSPPSRYTEASLVKKLEDEGIGRPSTYASIIKTIQDRGYVYKKGNALVPSWVAFAVVGLLERHFGRLVDYNFTASMEDDLDAIAEGRERRSDWLAAFYFGSDDRAEGTLAKLGGLKRLVGVNLEGIDAREINSITLFDDSDGRPVNVRVGRFGPYLERTIGEGDAAESQRANLPEDLPPDELTREIAEKLFSTPQEGRVLGVDPDTGHEVVAKEGRFGPYVTEIIPDDEKNGGAKKVKPRTGSLLKSMEISTVTLEEALKLLALPRVVGKDPESGDEITAQNGRYGPYLKKGSDSRSLATEDQIFTVTLDEALKIYAEPKRRGRQAAATEPLREVGNDPATGKPMVIKDGRFGPYVTDGETNASLRKGDEVATLTVERGAELLADRRARGPVKRTAKKTAAKKTTAKKSPAKKTAAKKTAKKSSS
(229) DNA topoisomerase 1 [Mycobacterium leprae TN]
8
MKGPRGSRSGRNGSPRRLVIVESPTKARKLSGYLGSAYIVESSRGHIRDLPRTAADVPAKFKSEPWARLGVNVDADFEPLYIITPEKKSTVTELKGLLQGVDELYLATDGDREGEAIAWHLMQTLKPRVPVKRMVFHEITEHAILAAAAHPRELDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFCSAVYWDIVAKLDASVSDPTAQPLTFVARLTAVDGLRVATGRDFGAMGTLRGDCEVSKIIVLDDLTATTLAAGLRGAQLTVASAEEKLYTRRPYPPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVSDSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVCNELDGDEFRIYELVWRRTVASQMADARGTTLSLRIEGRAGEQHVVFSASGRTLTFPGFLKAYVETVDELAGGEADDAERRLPHLTSGQLLDVIDLTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTVQDRGYVQKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIANGNEQRTNWLNNFYFGGNHGVSDSIARSGGLKKLVGVNIEGIDAREVNSIKLFDDEHGRPVYVRVGKTGPYLERLLAGDDGELTPQRANLNGTLTPDELTLEVAEELFATPHEGRVLGVDPETGHEIVAKDGRYGPYVTEVLPKHDDDYGAADQGTKKTKKGRRASASQGPKPRTGSLLRSMDLQTITLEDALKLLLLPRVVGVDPASGEEITAQNGRYGPYLKRGKDSRPLTTEDQMFIITLDEALKIYAEPKRAGRQSTSPPPLRELGTDPTSGKPMLIKDGRFGPYVTDGETNASLRKGDDVVSITDERAAELLADRRARGPVKRPAKKARKVPAKKAARLAPARGISQSPR
(230) DNA topoisomerase 1 [Mycobacterium leprae TN]
8
MKGPRGSRSGRNGSPRRLVIVESPTKARKLSGYLGSAYIVESSRGHIRDLPRTAADVPAKFKSEPWARLGVNVDADFEPLYIITPEKKSTVTELKGLLQGVDELYLATDGDREGEAIAWHLMQTLKPRVPVKRMVFHEITEHAILAAAAHPRELDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFCSAVYWDIVAKLDASVSDPTAQPLTFVARLTAVDGLRVATGRDFGAMGTLRGDCEVSKIIVLDDLTATTLAAGLRGAQLTVASAEEKLYTRRPYPPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVSDSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVCNELDGDEFRIYELVWRRTVASQMADARGTTLSLRIEGRAGEQHVVFSASGRTLTFPGFLKAYVETVDELAGGEADDAERRLPHLTSGQLLDVIDLTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTVQDRGYVQKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIANGNEQRTNWLNNFYFGGNHGVSDSIARSGGLKKLVGVNIEGIDAREVNSIKLFDDEHGRPVYVRVGKTGPYLERLLAGDDGELTPQRANLNGTLTPDELTLEVAEELFATPHEGRVLGVDPETGHEIVAKDGRYGPYVTEVLPKHDDDYGAADQGTKKTKKGRRASASQGPKPRTGSLLRSMDLQTITLEDALKLLLLPRVVGVDPASGEEITAQNGRYGPYLKRGKDSRPLTTEDQMFIITLDEALKIYAEPKRAGRQSTSPPPLRELGTDPTSGKPMLIKDGRFGPYVTDGETNASLRKGDDVVSITDERAAELLADRRARGPVKRPAKKARKVPAKKAARLAPARGISQSPR
(248) DNA topoisomerase 1 [Mycobacterium smegmatis str. MC2 155]
8
MAGGDRGSGGTGNVRRLVIVESPTKARKIAGYLGSNYVVESSRGHIRDLPRNAADVPAKFKSEPWARLGVNVDQNFEPLYIVSPEKKSTVTELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPRVPVKRMVFHEITEPAIRNAAENPRDLDIALVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFHSASYWDVTAELDASVSDPSASPPKFTAKLNTVDGRRVATGRDFDSLGQLKRPDEVLVLDEASAGALASGLRGAQLAVTSVEQKPYTRRPYAPFMTSTLQQEAARKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVHPSPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHSALDTDEFRLYELIWQRTVASQMADARGTTLSLRIGGSASSGEQVVFNASGRTITFPGFLKAYVESIDELAGGESDDAESRLPNLTQGQRVDAADLSADGHQTSPPARYTEASLIKALEELGIGRPSTYSSIIKTIQDRGYVQKKGSALVPSWVAFAVVGLLEQHFGRLVDYDFTAAMEDELDEIANGQEQRTNWLNNFYFGGEHGVEGSIARAGGLKQLVGGNLEGIDAREVNSIKVFDDSEGRPVYVRVGRNGPYLERMVDDPDNPGEQKPQRANLKEDLTPDELTPELAEKLFATPQEGRSLGIDPETGHEIVAKDGRFGPYVTEVLPEPEDGGDDGTAGTPAKKGKKPTGPKPRTGSLFRSMDLETVTLEDALKLLSLPRVVGVDPTTNEEITAQNGRYGPYLKRGTDSRSLATEDQIFTITLDEALKIYAEPKRRGRQAASAPPLRELGNDPVSGKPMVIKDGRFGPYVTDGETNASLRKGDDVLTITDERASELLADRRARGPVKKKAPAKKAAKKAPAKKAAAKKA
(249) DNA topoisomerase 1 [Mycobacterium smegmatis str. MC2 155]
8
MAGGDRGSGGTGNVRRLVIVESPTKARKIAGYLGSNYVVESSRGHIRDLPRNAADVPAKFKSEPWARLGVNVDQNFEPLYIVSPEKKSTVTELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPRVPVKRMVFHEITEPAIRNAAENPRDLDIALVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERERMAFHSASYWDVTAELDASVSDPSASPPKFTAKLNTVDGRRVATGRDFDSLGQLKRPDEVLVLDEASAGALASGLRGAQLAVTSVEQKPYTRRPYAPFMTSTLQQEAARKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVHPSPRQYTRKVKNAQEAHEAIRPAGDVFQTPGQLHSALDTDEFRLYELIWQRTVASQMADARGTTLSLRIGGSASSGEQVVFNASGRTITFPGFLKAYVESIDELAGGESDDAESRLPNLTQGQRVDAADLSADGHQTSPPARYTEASLIKALEELGIGRPSTYSSIIKTIQDRGYVQKKGSALVPSWVAFAVVGLLEQHFGRLVDYDFTAAMEDELDEIANGQEQRTNWLNNFYFGGEHGVEGSIARAGGLKQLVGGNLEGIDAREVNSIKVFDDSEGRPVYVRVGRNGPYLERMVDDPDNPGEQKPQRANLKEDLTPDELTPELAEKLFATPQEGRSLGIDPETGHEIVAKDGRFGPYVTEVLPEPEDGGDDGTAGTPAKKGKKPTGPKPRTGSLFRSMDLETVTLEDALKLLSLPRVVGVDPTTNEEITAQNGRYGPYLKRGTDSRSLATEDQIFTITLDEALKIYAEPKRRGRQAASAPPLRELGNDPVSGKPMVIKDGRFGPYVTDGETNASLRKGDDVLTITDERASELLADRRARGPVKKKAPAKKAAKKAPAKKAAAKKA
(1195) DNA topoisomerase 1 [Mycobacterium marinum M]
8
MADPKTKGPGSRSSGGNGSGRRLVIVESPTKARKLAGYLGPRYIVESSRGHIRDLPRAAADVPAKFKSEPWARLGVNVDADFEPLYIISPEKKSAVSELKDLLKDVDELYLATDGDREGEAIAWHLLETLKPRVPVKRMVFHEITEPAILEAAENPRDLDMDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRMIVQRERDRMAFRSASYWDIVATLDASVSDPKAAPPTFVARLTSVDGLRVATGRDFDSLGTLRKADEVTVLDEARAAALATGLHGAQLSVASVEEKPYSRRPYPPFMTSTLQQEAGRKLRFSGERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVASSPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGDEFRLYELIWQRTVASQMADARGTTLSLRIGGSAGEQQVVFSASGRTLTFPGFLKAYVETVDELVGGEADDAERRLPNLTPGQRLDAVELTPDGHTTNPPARYTEASLVKAFEELGIGRPSTYTPIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGHLVDYGFTAAMEDELDAIASGQERRTDWLNNFYFGGDHGVSDSVARAGGLKKLVGVNLEGIDAREVNSIKLFDDEQGRPIYVRVGKNGPYLERTITGEDGEPTPQRANLNDSLTPDELTLVLAEELFATPQEGRVLGIDPESGHEIVAKDGRYGPYVTEILPEPPAPEAGTEAPAKKTKKATGPKPRSGSLLRSMDLQTITLEDALKLLSLPRVVGTDPASGEEITAQNGRYGPYLKRGTDSRSLATEDQIFSITLDEALKIYAEPKRSGRQSASAPPLRELGTDAASGKPMVIKDGRFGPYVTDGETNASLRKGDEVASITDERASELLADRRARGPVKRAAKKTTRKSPAKKAVKRA
(299) DNA topoisomerase 1 [Mycobacterium africanum GM041182]
8
MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
Family distribution
Taxonomy tree
Mycobacteriaceae