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Taxon : Lachnospiraceae
Informations
Name
Lachnospiraceae
Rank
family
# topoisomerases
25
Lineage and sub-taxa
Lineage
Bacteria
>
Firmicutes
>
Clostridia
>
Clostridiales
>
Lachnospiraceae
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(92) DNA topoisomerase III, bacteria and conjugative plasmid [Ruminococcus torques L2-14]
7
MAQHKLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRYDDLPILPEHWQMVVGKDKKKQFDILKKLMNAPDVTEVVNACDAGREGELIFRSVYELAGCKKPMKRLWISSMEDSAIREGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYHRTLNIGRVMSPTLALIVQREAEIDTFQPVPFYTVALELPGLTVSGERMADKAAAKQLKETCRGANVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTYPRTDSRYLTSDMADSLPVLVNLVANAMPFRKGIAITCDPQTVINDKKVTDHHAVIPTRNLKDADLSALPAGEKAVLELVALRLLCAVAQPHIYSETVVIAACAGGEFTAKGKTVKHPGWKALEDAYRAKMKDAEPKKEGAEKALPELTEGQTLSVAAAIVKEGKSSPPQHFTEDTLLSAMETAGKENMPEEAERKGLGTPATRAGILEKLVSAGFLERKKSRKTVQLLPSHDAVSLITVLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLDGISTMLKDLVGTYQVIKGTEYLFTPPREVVGKCPRCGGEVAELQKGFFCQNDSCKFAIWKNNKWWDAKKKQPTKAVVSALLNDGCVRVTGLYSEKTGKTYDAAVVLEDDGQYANFKLEFDQRKGGSR
(644) DNA topoisomerase 1 [Ruminococcus torques L2-14]
1
MAHYLVIVESPAKVKTIKKFLGSNYTVAASQGHVRDLPKSQLGIDVENDYEPKYITIRGKGEILATLRKEAKKSDKVYLATDPDREGEAISWHLAAALKLDEKKMRRITFNEITKNAVKASLKAPRDIDMDLVDAQQARRELDRMVGYKISPLLWAKVKRGLSAGRVQSVALRIVADREAEIDAFIPEEYWSLDAQLKVKGEKRPLTAKFYGTEKKKMTIHSKEEMDEILKKLENEEFQITDIKNSERTRKAPLPFTTSTLQQEAAKALNFGTQKTMRIAQQLYEGVDIKGNGTVGVITYLRTDSTRISEEADAAARSYIAETYGEAYVAEGTKTKSADKKIQDAHEAIRPTDITRTPAAIKDSLSRDQFRLYQLIWKRFTASRMQPAKYETTAVKIGAGEYCFTVSTARVAFDGFRSVYVEAEEEKEESNVLVGHLSMDSVLTKEEFDPKQHFTQPPAHYTEASLVKTMEELGIGRPSTYAPTISLILGRRYITKEGKNLYLTEIGEVVNNIMKQSFPSIVDVHFTANMEGLLDMVEEGKVPWKEVIRNFYPDLEEAVEIAEKELEEVKIEDEVTDVICEECGRNMVIKYGPHGKFLACPGFPECRNTKPYLEKIGVPCPVCGKEVVIRKTKKGRKYYGCEDNPECEFMSWQKPSSKKCPECGGYMVEKGNKLVCADEKCGYVETIKKED
(489) DNA topoisomerase [Ruminococcus torques L2-14]
7
MGKSVYIAEKPSVAQEFAKALKLNTKRRDGYLESDEAIVTWCVGHLVTMSYPEEYDPALKRWNLQTLPFIPEEFKYEVIPSVAKQFQIVSGILNREDVDTIYVCTDSGREGEYIYRLVEQEAHVEGKKRRRVWIDSQTEEEILRGIREAKDLSEYDNLGASAYLRAKEDYLMGINFSRLLTLKYGNSISNFLQTKYSVISVGRVMTCVLGMVVRREREIRDFVKTPFYRVLSTIDAQGHTFEGEWRAVKGSRYFESYDLYKENGFKERKKAEELIQYLQTPDDESVNVAGIQRQLGLNCRIESIEKKKEKKNPPLLYNLAELQNDCSKRFKISPDETLRIVQELYEKKLVTYPRTDARVLSTAVAKEITRNLNGLSKYPMAAPYMQDILNFGSYKTLAKTRYVNDKQITDHYAIIPTGQGLNALSTVSSTAKGVYDLIVRRFLSIFYPPAVYQKVAIVTKIKEESFFSSFKVLAEEGYLKVAGIPKKKASQTATKDSSNGNSENTNNDTNDEAGSDSSDQSLDTGLFEVIKSLKKGAVLQVRALDIKEGETSPPKRYNSGSMILAMENAGQLIEDEELRAQIKGSGIGTSATRAEILKKLVNIKYLALNKKTQVITPTLQGEMIYDVVDHSIRSLLNPELTASWEKGLNYVAEGSITSDEYMRKLDHFITSRTVGVKGLNNQYQLRACYEKAAGFYPSVNNNKTIGRTKTGNKSK
(292) DNA topoisomerase 3 [Coprococcus catus GD/7]
2
MKTLVIAEKPSVGRDIARVLQCTRNSQGALEGEKYIVTWALGHLVTLADPEGYDAKYKSWRGEDLPMMPQHFKLVVIKQTHRQFQIVKNQLLRKDVGTIVIATDAGREGELVARWILKIAGNKKPVKRLWISSVTDKAIREGFKNLKDGRAYLNLYAAAEARAEADWLVGMNGTRALTCRYNAQLSCGRVQTPTLALIASREQEIKSFVPKKYYTLTTVSHGMTWNWQDGKSGSNRSFDRGRIQSIAEKAEKDEMVITDVQRTVKKSYSPGLYDLTELQRDANKRFGYSAKETLNIMQRLYENHKVLTYPRTDSRYIGKDVAETLKERLQACAVGPYRKVAGKLLLQPIRMDKRFVDDSKVSDHHAIIPTEQFVQLDHMSSEERKIYDLVVRRFLAVLYPPCEYEQIKLTGSCAGEKWTAGSRMMKEAGWQQAYESEWEEEDDDSLMTVTSMPKLEKGRKDTVMRPKVSEGQTKPPAYYNEGTLLTAMEKGNLGTVATRADIIDKLFNSFLMEKKDKDIRVTSKGRQLLGLVPEDLKKPELTADWEKKLLAISEGRLKKDVFISEIRGYTEEIVKEIAGGEGQFRHENLTNHLCPNCGKRMLSVQGKNSKMLVCQDRSCGYRESIARKTNARCPKCHKKMEMYGKGDAQTFVCTCGYKEKLSAFQNRRKKEGAGVSKRDVQQYMKRQQKEANEPINNAFAAAFAKLNLETKEGE
(1278) DNA topoisomerase [Coprococcus catus GD/7]
7
MYLVIAEKPSVSKAIAEVIGAQEREDGYLQGTDCMVSWCFGHLAEYVSPDAYDEKFNQWRYEDLPIIPKDWKVTVSEDKKDQFYILKRLLNSPEIEYVVNACDAGREGELIFKHVYDLSGSKKPVKRLWISSLEDSAILDGMQHLRSAEEYRHLAEAAVCRSQADWLVGMNATRAYTTKYFKKLTVGRVQTPTLAMLVERAGQISNFQKEKYFNVELDCDGIPAVKPKIFDPDEAEQLRSRCQGSEAIVTAVKETEKKVKAPKLYDLTTLQREANRIYGMTAKQTLDTAQSLYEKKLITYPRTDSQYLTEDMEQTARNVVRQIYEKYQLTGPFDQPEQPDVKKVMNNSKVTDHHAIIPTMELASCHLDELKSWEEKILFLIAVHTVMAMSKDHIYQETEIEVECQEEIFKAKGKIVLQDGWKLFENCFKNKDRMAIVDPDQEMKERMPKVTQGQTFYAVDAEKTEHFTSPPKPYSEDTLLAAMETAGNKEFDEDTEKKGLGTPATRAGIIEKLVYSQYATRKGKQIIPTDDGKVLVEILPDFLKSASMTAEWENQLLLMEHGEIAPEQFMTGIKNMLTMMLNGCDAISEEETRRFQTRESIGTCPVCGSLVYESKTNFYCSNHDCHFALWKDNRYLQSMEKNMDKKMAAELLKSGCVHVKDLYSRKKNMYFEADLHMDADETGRVKFSLSFPKKKPKNKSKKK
(1772) DNA topoisomerase 3 [Clostridium lentocellum DSM 5427]
2
MGKILVFAEKPSVGKDIARVLKCTQKQNGFFEGPKYVVTWAMGHLVGLSDPEAYGNQYKTWSMETLPMLPERMKLTVLKGTGKQFQIVKSLMLRKDIDEIIIATDAGREGELVARWTIDKVGVKKPIKRLWISSVTDKAISEGFKNLKPGKDYENLYKAAVCRAEGDWLVGLNVTRALTCKFNAQLSAGRVQSATLAMIVAREEAIKNFQPKPYFTLSAKCKGIQLAYKGKKGDRFFDEKQIVTLIGKLEGSKAQVTEYKETSKKQYAPALYDLTELQRDANKRFGFSPKETLSVMQRLYENYKVLTYPRTDSRFLSEDIVPTLKERINAIAIGPYKVGAREVLKNGIKSSKHFVDNSKVSDHHAIIPTEESPDLSKLNSDERKIYDLVVKRFLSVLLPPMAYNEGVLEVSSEGECFVAKGKKVIEPGWKMLYEIEADEDEDEVVQSLPEVKKGETVVLEQFFKTKQMTKAPSRFTEATLLSAMEKPHQYVEVDQKAAKTLGETGGIGTVATRADIIEKLYNMFYIEKSGKEIVPTSKGKQLIELVPVDLKSPLLTAEWEMALEQISKGKQDPKAFMKKIRVYSEELVQSVKGSGEKYIHDNLTGKRCPECNKLMLEVKGKHGKLYVCQDRNCGYRENISRFTQTRCPNCHKKLELRGEGEGQIYVCTTCTFREKLSVFNKKYRSESKKVDKKSVQKYLKEQTKKEEGNFAFAEAFAKLNK
(1795) DNA topoisomerase [Clostridium lentocellum DSM 5427]
3
MKKVIIAEKPSVAKNIADAFDIKTKRDGYYEGEDYLITWAFGHLLQLYDAKDYDESMKSWRLEKFPFIPEEFKYKVKSDGKNKAIEDVGARKQLNIIKDLIDREDVESVISATDFDREGQVIGDEIFLYFNEKKPIYRILLNEWTPEEVKKGISQLRPNEEMKSLQDAGIGRQWADWMIGINLTSVATVKYNSGSKKILNIGRVLLPTLKIIYDRDKEIEQFEASTYYKLLANFKTSQDEVFEGTYYEKDEEGKDNEKFDNKATLESMVELIKNKPAQIVEKQVEKKKEYAPFLFNLSNLQGYITSKYKGWTSDKVLKVAQSLYEKKYITYPRTGSLALEESLKGRTKKVLDTLKIGLPYEGQICFADHKRIFDNSKVESHSAIVPTYIIPKSLTPDEQVVYNAVKNRFLMQFLPIAEFEETKLITKIIDVPEESLKGVFISKGKVQLVEGWRIVEKFEAKGTKEGKENKDTLLPQVTQDELVEMKNANVAEVTRKPPKAHTEKTLLRVMETCGKSFKGDEKEEGKEESEEDTLKMMASILSGFSIGTPATRAETIKKLKDAEYIRAKGKSLVCTDLGKALVETFPAKQLLDLEYTGRLEKTLSDIEKGKFQKDEFLSMIKAFTEEAVEAIKNDTRVLSGTKVEVPKNMEPVGVCPVCGNAVVENEKAFGCVNWKSGCKYTIWKNDKYITMLGKNVTRQMVELLLKNGKVGFRNLKGRNGNTYAAYLKYVKNDQTGYFNWEQEFI
(440) DNA topoisomerase 1 [Clostridium lentocellum DSM 5427]
1
MADNLVIVESAAKVNTISRFLGKNYKVEASIGHVRDLPKSQLGVDTANNYEPKYITIRGKGELLQKLRKDVKNAKCVYLATDPDREGEAISWHLYHALKLQEKKVCRITFNEITEQAVKEAIKHPRDINTDLVDAQQARRVLDRLVGYEISPILWKKVRKGLSAGRVQSVTLRLISDRDKQIREFVEEEYWSITANLQQGKGKTFEAKLDTYKNEKCDINNEEEAKKIVKACKKGHFQVVSSKKGTRVKNTVLPFTTSTLQQEAAKHLGFSTQKTMNIAQQLYEGIKVGKKEVGVVTYIRTDSIRIADKAKEEATTYITQKYGEQYLGAKKQIEKAKKAHIQDAHEAIRPTYMEYEPNEIKEYLSRDQFRLYQLIWNRFVASQMAPAQYETYSIKVQNGDYEFKASYSIELFDGFIKVYNLGEEKAKKEAKFQVEEGEQLVCGSIIPNQHFTQPPAHFSEATLVKTLEENGVGRPSTYAPTITTLLARGYIVKESKILYMTELGEVVNQIMKEYFDEVVDVDFTANMERILDEIASGNVEWKEIIKSFYPHFHHTVEYAESQIENIDLTEHTDIPCEKCGTHMVVRYGKYGKFLGCPNFPECNGTKPWYEETGISCPECNGKILMKKTKKGRSYYGCEHNGEGCEFMSWDKPTGEKCPICGEALIEKGNSKNKKIVCRNSKCNYGKQNKN
(906) DNA topoisomerase 1 [Coprococcus sp. ART55/1]
1
MIRITGNLQKGQIAMAKNLVIVESPAKAKTIKKFLGSNYEVIASNGHVRDLPKSQMGIDVDNDFEPKYITIRGKGDILAALRKAVKKADKIYLATDPDREGEAISYHLMKALKLENKDYKRITFNEITKNAVKNSIKQARDIDMNLVDAQQARRVLDRLVGYKISPVLWAKIKRGLSAGRVQSVALKLVCDREKEINDFIPQEYWTLDANLTGGKLKKPITFKFTGDGKNKEEISGRAALDEILSGLQDGEYVVKSIKESERNKKAPLPFTTSTLQQEASSKLNFATSKTMRIAQQLYEGVDIKGRGTIGLITYLRTDSTRISEEAVAAADKYITDNFGEIYIGDSNGRAKTDKKIQDAHEAIRPTDVTLSPVMVKEQLSRDQFRLYQLIYNRFLASQMAGAVYSVKSVKVSCGDATFQTSASKIAFDGFLAVYNLDNDRGETVAGINNLAEGDVLELDGFEEKQHFTQPPARYTEALLVKTLEELGIGRPSTYAPTISTILARRYITKEQKKLYVTAIGDAVNQSMEQAFPVIIDVNFTANMESLLDKIGEGTVDWKVVVRNFYPDLDEAVKKAEAELESIKIEDEVSEEVCDVCGRNMVIKYGPHGKFLACPGFPECRFTKPFYEKIGVTCPKCGGDVVIKTTRKGRRYYGCINAPECDFMSWAMPSNEKCPECGKYMIVKGNKLVCSDQECGYTCNNKAAETADK
(460) DNA topoisomerase III, bacteria and conjugative plasmid [Coprococcus sp. ART55/1]
7
MQLVIAEKPSVAKSIADVLGALDRQDGYFEGGGYLVSWCVGHLIELAEPESYGEQWKKWTYESLPVNPEHWQYEIKEDTKEQYDVLYGLLHDSRVDEVVCATDAGREGELIFRLVYNMASCKKPMKRLWISSMEESAIREGVENLKPGSDYDHLYHSALCRQEADWLVGINGTRLFTVLYGGKVLKVGRVQTPTLAMLVEREAKIMNFKKEQYFMAHILCGGVDAVTERIDNKTEAENVAGACRNGQALVTSVEKEEKTVSPPKLYDLTTLQRDANRLFGFTAKQTLEYTQSLYEKKMCTYPRTDSQYLSDDMEQTAGNVIEAIFSSILFEENRMFNPDIKRVLNSKKVTDHHAIIPTMEIAKADLAALPETERKILSLVANRLLCATGEKHLYETVKAELSCGGYTFTTSGKSVLKNGWKDFEDAFKRSFKATEEKEQEDKKLPELSEGQTFDGVQTKISEHYTTPPKHFTEDSLLSAMERAGNEDMSDDVERKGLGTPATRADIIEKLVKDGFVKREKKQMLPTEDGMKLITVLPDVVKSSKLTADWENALTLVAKGEMEREDFMADIETMESDLIHTYHEVSDEQKKMFAQEQKVLGKCPNCGGEVVKGKYGAFCKNKCGMNVSRIMGVALSDEQVESLLAGKKTLLKGITSKAGKKYDAYIIPSGTEEYHYTKDGEEKSGAQFKFVMEFPNKKFTGKKK
(552) DNA topoisomerase 1 [Butyrivibrio proteoclasticus B316]
1
MASKTTTTKKNSLLIVESPTKVKAIKKFLGNGYDVAASNGHVRDLPKSQMGVDVEHDFEPKYITIRGKGDVLADLRKKVKKADHVYLATDPDREGEAISWHLIAALKLDEADAKIQRVTFNEITKNAVKEAMKHPRDIDMNLVDAQQARRVLDRMVGYSISPLLWSKIKRGLSAGRVQSVALRIIADREEEIESFIPSEYWTLDVNLAAEGEKKPLVAHYYGTGNDKKEIKSKEELDKICASLKGAKYVVSDVKKGERNKKAPLPFTTSTLQQEASKALNFSTQKTMRVAQQLYEGIELGKQGTVGLITYLRTDSTRVSDEAVAAANAYISSNFGDKYLSEGTTAKKSDAKIQDAHEAIRPTYVENTPVVVKEFLSRDQFRLYQLIWRRFMASRMAPAKYETTSVKIDAGEHRFTVAASKTVFDGFLNVYTDEDDQIEKNVLMKNLDINTKLSFDSFDSAQHFTQPAPHYTEASLVHDLEALGIGRPSTYAPTISTILARHYITKENKAIFITELGQAVNKMMNDAFPQIVDVNFTSNMEALLDGIADGNVKWKTVVENFYPDLNEAVEAAEKEMEKIQVQDEVTDEICPNCGRNMVIKYGPHGKFLACPGFPECKNTMPYFEKIGVECPKCGKDLVLKRTRKGRIYYGCIGSPECDFMSWARPVKEKCPKCGKYMVAKSNKLACSDQECGFSCNKDELKKE
(294) DNA topoisomerase [Butyrivibrio proteoclasticus B316]
7
MAKKLIITEKPSVARDFARVLNVSGNNNGYIENDQYVISWCFGHLVEMVYPEEYDPKYKKWRLEDLPFLPAKYKYGVIKNSADQYKLINNLLHREDIDTVYWAGDSGKEGQTIEENIRNYGGVRDGMTELRVWIDSMTDEEVRRGIAQARPMSDYALLGESGIMRAIEDYSLGINFSRALSVKYGKLINDAAATKSYTAIAIGRVMTCVLGMVVRREREIRNFEKTPFFRIVGSFSDAKILAEWKAVSGSAYFESPLLYKENGFKKEDSAKALIDSFNGKEAVIDSIETGNSKKRAPLLYNLTELQADCTKRFKISPSQTLEIAQELYEKKLTTYPRTDARVLTTAVAKEIYKNVKGLSAVNEVSGFVDHVLKNGLYKGIEKSPYTDDSKVTDHYAIIPTGQTSAMGSLSPLAMNVYLLICRRFVSIFYPSAEYKTAKLQIAVGNEKFFAAAKVLVSPGYLEVAGIPKDKKAEDKKGDEEGNSSEDEEDVGISKEEFLKFVENAHKGDRISVNDYMIKEGATAPPKRYTSGDLVIAMENAGNLIEDEELRETIKKKGIGTAATRAAIIQKLIDNKYLAQSKSQIITPEKLGEMIYEVVYLSVPTLLNPEMTASWEKGLEGIYNGSVNGQDYRAKLEEYIRRETGKLIEKDLTTEIVGRINQFTGKESKGLASRKPIGIKCPVCGGEITTTSFGYGCSNYFNDQIKCTFSVGRIAGKDLDEETVKTLITEGKTGVIEGFVGKNKSSFSASLRLGKDENGKYAISFNFDDVPTVYVDNMNCPACGGRIIRTVNGYSCENRGKEEGGCYFYLGEVAGKKLTEEQVRTILSGEETEVIRGFKSKNNKPFNAKLVMKTSENGKKEITFDFEGVEPDYLADVVCPDCGGRIIKKTVGFGCENFKADDPQSCKFFIGKIAQKQISEANVIELLKEGRTGTIRGFKSKDKKPFDACLVMKKNENGVSEISFDFENVEAKTVKGVTCPLCGGDIVKTPFGYGCSNYKKDDPENSCKFNIGAIAGKNLKDAQIKELLLTGETTKISGFKSKSGKPFEAKLALDKGEDGKVKGIRFVFESEDEVMEDAKCPICGKQIIKGHLGYRCEDYKKGDEGCSFFIGKIAGVMIDKENFKKLVNEKITDKIAGFTSKKGTSFDAKLAFDEKFNVVFNFDN
(712) DNA topoisomerase 1 [Roseburia hominis A2-183]
1
MAKYLVIVESPAKVKTIKKFLGKNYEVVASNGHVRDLPKSQMGIDVEHDYEPKYITIRGKGDILAKLRKEVKKADKVYLATDPDREGEAISWHLSQALKLDGKNVRRISFNEITQNAVKASLKQPRDIDMNLVNAQQTRRILDRIVGYKISPLLWAKVKRGLSAGRVQSVALRIICDREDEINAFIPEEYWTLDAKLKADGEKKPLTAKFHGDENGKLAITCREEADRIMDEIRGERFEVLEVKKGERVKKAPLPFTTSTLQQEASKTLNFPISKTMRIAQQLYEGVDVKGQGTVGLITYLRTDSVRISDEADADARAYIAQNYGEEFVATQTVTQKGGAKIQDAHEAIRPSDIARTPAVVKESLSRDQFRLYQLIWKRFAASRMASAVYETTNVKIGAGKYRFGVAASKVSFEGFMSVYTSEDDEKDTNNVLLKGIDEDTKLTLDTFDEKQHFTQPPAHYTEASLVKTLEELGIGRPSTYSPTITTLLGRRYIVKEAKNLYVTELGEVVNQIMKESFPSIVDEHFTANMESLLDSIGEGAVNWKTVVRNFYPDLEAAVEVAEKELQKVKIEDEVTDVVCDQCGRNMVVKYGPHGKFLACPGFPECRNTKPYLEKIGVPCPKCGKDVVLRKTKKGRKYFGCENNPECDFMSWSRPVAEKCPKCGGYMVVKGNKIACADAGCGYTRDRKADEDTK
(610) DNA topoisomerase III [Roseburia hominis A2-183]
7
MAQHKLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRYDDLPILPEHWQMVVGKDKKKQFDILKKLMNAPDVTEVVNACDAGREGEMIFRSVYELAGCKKPMKRLWISSMEDSAIRKGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYHRTLNIGRVMSPTLALIVQREAEIDTFKPIPFYTVALELPGLTVSGERMADKAAAEQLKEACQGVNVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTYPRTDSRYLTGDMADSLPVLVNLVANAMPFRKGIAITCDPQTVINDKKVTDHHAVIPTRNLKDADLSALPAGEKAVLELVALRLMCAVAQPHIYSETVVIAACAGGEFTTKGKTVKHPGWKALEDAYRAKMKDTEPKKEGVEKALPELTEGQTLSVSAAIVKEGKSSLPQHFTEDTLLSAMETAGKDDMPEDAERKGLGTPATRAGILEKLVSAGFLERKKNRKTVQLLPSHDAVSLITVLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLDGISTMLKDLVGTYQVIKGTEYLFTPPREVVGKCPRCGGEVAELQKGFFCQNDSCKFAIWKNNKWWAAKKKQPTKAVVSALLNDGCVRVTGLYSEKTGKTYDAAVVLEDDGQYANFKLEFDQRKGGSR
(1268) DNA topoisomerase [Roseburia hominis A2-183]
7
MQLVVTEKPSVAQAISHVIGAKERKDGYMEGNGFLVSWCVGHLVELAQPEMYSEAWKKWSYESLPMIPEQWQHEVKKETATQYKILKNLMHDTRVESVVCATDAGREGELIFRLVYEQAGCRKPMKRLWISSMEESAIRDGFENLKPGSDYDSLYQSALCRQQADWLVGLNGTRLFTVLYGGKVLKVGRVQTPTLAMLVDREVKIMNFEKEQYYMAHILMDGIDAMTERIDDKARAESIAAACESQSGVVRSVIKENKSVAPPKLYDLTTLQRDANRIFGFTAKQTLEYTQSLYEKKLVTYPRTDSQYLSDDMEETAKAVIGAVYQAILFEEQTGAEPDIKRVLNSKKVTDHHAIIPTIEITKTDLSAVPEGEMKILSLVANRLLCATGKKQLYETVKAEFSCGGYSFHVSGKTVLQNGWKEFEAALKRTYRVEKTDEDKEEKKLPELSEGMTFPVIQTKVTEHFTQPPKHFTEDSLLSAMERAGAEDMGDEVERKGLGTPATRADIIEKLVKDGFVKREKKQMLPTEDGMKLITVLPDMVKSPKLTADWENTLTLVEKGEYTMQEFMDGIEDMVRELVQTYHSISDDQKSLFGTMQEVLGKCPKCGSDVVKGKFGAYCKQKCGMNVGRAMGATFSDTQMKSLLEGKKTLVRGLKGKKGSYDAYLIPEGIEDYSYIKDGKEIKGSQYKFKMEFPPRKSK
(10) DNA topoisomerase [Roseburia hominis A2-183]
7
MAKSLIITEKPSVAQEFARILGVSGRNDGYIENDGYVITWCVGHLVEMVYPEEYDERYKKWRLEDLPFLPRDYKYNVIPSVSRQYDVVHKMLHREDIDTVYWAGDAGKEGQTIEENIRKFGGVREGMKELRVWIDSQTEEEILRGIREAKDMSEYDNLAKSGVMRTIEDYAMGINFSRAMSVKYGKLLNDAAGTSSYTAIAVGRVMTCVLGMVVIREREIRNFTETPFYRVVGTFHPEGEEECRITAEWKAIEGSKYFESPLLYKENGFKKEESAQTLIAELKGQEALIDSVETGTQKKRAPLLFNLAELQAECSKRFKISPDETLQVAQDLYEKKLTTYPRTDARVLSSAVAKEITKNISRLKNFAPVAPYVERIMKEGRCRNIANTQYTDDSKITDHYAIIPTGQLTELESLNSLERSVYEMIVRRFLSIFYPPAEYQTVKLVVAAGGEKLYTSAKQLKVPGYLEIAGIPKSAKERNAAKTDGEEQTQGGDAEAAQEEEENAGLLAYADKLQKGETLFSDGYVIREGKTSPPKRYTSGSMVLAMENAGQLIEEEELREQIKGSGIGTSATRAEIIKKLVRVGYLNLNKKTQVLTPERLGEMIFEVVSMTVPALLNPKMTASWEKGLDGITRGAVVMEDYRSKLEDFIRRETVAMIEQDLTGQIATRIHPLVGKGGKGLAAKRSLGIPCPVCGGTIETTPFGYGCSNYQKDGGGCRFSIGTIAGRDLNDEEVKELLTEGHTGVLSGFVSKSKKKFSASLILEKDDEGKVSVGFDFSKNQPEILEGVVCPVCGSAVEITPFGYSCVKHHEHPDECYFSVGKIAGKALGVDDLTELLTTGKTGLIRGFTARNKKKFNACLKLEQTEDGRKNIAFDFSQNDAAVVPDVVCPICGGAIVETSFGFGCANYRQDDPDSCRFAIGTMAGKDLNAAQVKELLNQGRTGTIRGFKSKSGKKFDACVALEHTEDGRIELRFDFEHVEAKKIKDVVCPICGGDIVATPFGFGCANYVKDDPNSCRFSVGKMAEKALTEANVKELLTNGRTGTIRGFKSKSGKKFDARVALAKDEKGKVTGLKFDFTDLEAPKVKDVKCPVCGGDIVKTMFGYGCANYSKENPDSCRFAIGKIAGVSLKEAQVKELLLRGKTDVIKGFVAKTGMKFDAPLKLTPEGQIAFDFPEKPKPVETTLACPKCGKMLKKSQWYYECECGFKVSHTVAKVALTEEVMRELLETGKTKDKVTGFVSKAGNTFDTCLKLEDDRIVFDFDNPGTKREGASDGKGGERMFYEELEENAQPQPLAAEDGAQYIEEDVPPFYDAMAEEYAAYEEEEAKQQAAASNFLDEFPG
(770) DNA topoisomerase 1 [Butyrivibrio fibrisolvens 16/4]
1
MAKNLVIVESPAKVHTIKKFLGSSYEVMASQGHVRDMPKSQLGFDPENDFEPKYITIRGKGELLAALRKEVKKADKIYLATDPDREGEAISWHLTHALNLQDKKVYRITFNEITKTAVKNSLKNPREIDMDLVDAQQARRMLDRMVGYEISPLLWAKVKRGLSAGRVQSVALRIICDREKEIEQFIPQEYYTLDVLLDAAGSKKPIVAKYYGDTSGKKDISDKESLDKIMESLKGASFNIASIKRGTREKKAPLPFTTSTMQQEASKALNFSIQKTMSVAQQLYEGVTVKGYGTVGLITYLRTDSTRVSDEAKAAAESFISSNYGDNYLSESAGNAKKNSGKVQDAHEAIRPANIELIPSEIKDSLTRDQFRLYQLVWKRFVASQMANAVYDTVSLSVSAKDQVFTASESSINFDGFMMIYTAADDEEESKTHPLAKLTEDTKLSFNSFEEKQHFTQPSPHFTEASLVKTLEELGIGRPSTYSPTITTLIKRHYITKEAKNLFVTELGEVVNSIMVDSFPIIVDDKFTANLELLLDGVEEGTVDWKSVVRNFYPDLEKAVKVAEEELAKVEIHDEVTDVICEECGRNMVIKFGPHGKFLACPGFPECRNTKPFLEKIGVPCPKCGGDVVIRKSQKGRKFYGCSNHPECDFISWSKPTTVKCPKCGTYMVEKGNKLVCGNDECRFVQSQN
(189) DNA topoisomerase III, bacteria and conjugative plasmid [Ruminococcus obeum A2-162]
7
MKLVIAEKPSVAMSLAAVLGATERKDGYLEGSGYLVSWCVGHLLELAQPEAYKEQYAKWRYEDLPILPENWKYEVPKDKKTQLALLCRLMKDKRVDSVVCATDAGREGELIFRLVYEYAGCKKPMERLWISSMEDAAIREGFDHLHPGSDYDKLYDAAVCRAGADWLIGINATRLFSVLYGVTLNVGRVMSPTLALLVQRESDIESFISKPFYVPEITCGGFTASGEKMTERSEAEKIRMDCDHNSAFVRSVEKQVKTIQPPRLYDLTTLQRECNRIYGYTAQQTLDYVQSLYEKKLATYPRTDSQYLTKDMQATAASLILWLRDNMTFGKGYAGEPDIDRVTDDSKVTDHHAIIPTVEIARTDLSELPSGERDVLTLLAVRLLCATTQVHRFEAVTAILDCQGYTFTAKGKTILQSGWKEVERIHRMSIRQSETERRENEDAALPVLKEGQTFETVSASLREGKTSPPKHYTEDTLLSAMETAGAEDMPEDAERKGLGTPATRAATLEKLVSAGFVQRKKKQLIPTEKGKNLIAVLPDNIKSPILTAEWESMLKQVEHGELSATSFMDQIADMSRTLVKEHTTPEERFADLFPSSKGTAHEAVGVCPRCGAPVFEGKKGFFCGNRECSFALWKDNRFFSSKKKSITKSVAAALLKEGRISMSGLYSEKTGRTYDAEVILDDTGGKYVNFKLEFPVKKGRRK
(658) DNA topoisomerase [Ruminococcus obeum A2-162]
7
MSKFLVIAEKPSVAQSYAKNLSAYKKEDGYLEGESCIVSWCLGHLAEYAQPEEYDPKYEKWQFDDLPILPQVWKLKVSRDKKKQFDVLKSLMNRADVDYLVNGCDAGREGELIFQRVYDLAGCRKPVKRLWISSMEDTAIRTGFQTMKGAEEYRNICMAAVCRAQADWLIGMNGTRAYTTCYFKRLVVGRVQTPTLAMLAERQDKIEHFQKEAFYKVALTDGRLTVVSENIANEEAADLLASLCMGSEAVITQVKKEQKKAFPPKLYDLTSLQREANRYFGYTAKKTLDMLQELYEEKLVTYPRTDSQFVTEDMRDTVEELVGKMPVLLPFLDYGQLGHNITRVINNAKVSDHHAILPTKEAVEKGISDLPADKKNLMMLVCQQLVQATGEEYQYEQTDITVKCQEHDFTARGKVPVQMGFKEAGNAFKNQCVKAKPEEETEKETSIPYSYEEGMTLSPVKAEKTVHFTSPPKPFNEDTLLAAMETAGNKDFDSETEKKGLGTPATKAGIIEKLVSSGYAVRKGKQILPSTEGRELVNVMPAYLKSAAMTAEWENQLLMMEKGQITDTQFMGEITSLVGKILSVCREIPEVERRRFQKAREVIGKCPVCGSDVYEGKQNFYCSNRQCDFALWKENRFLGSMEKTLDKKMAVELLDKACTHVKGLYSRKKDIKFDADLLLTLEDGKPRFHLEFPKKKKK
(1000) DNA topoisomerase [Ruminococcus obeum A2-162]
7
MAKFLVIAEKPSVAQSLAKNLSAYQRKDGYLEGNSCIVSWCLGHLAEYAPPEIYDEKYAKWQFEDLPIIPKVWKVQVSEDKKKQFDVLCNLINRADVAYLVNGCDAGREGELIFKRVYDLAGCQKPVKRLWISSMEDEAIQKGFQSLTDGREYAGLCNAAVCRAQADWLIGMNATRAYTTRYFKRLVVGRVQTPTLAMLTERKEKIEHFKKEAYYKVSLSDGKLMVTSESIPLEMEAEELRKLCDGTEALVTRVKREQKKTFPPKLYDLTSLQREANRFFGYTAQKTLDMLQELYEEKMVTYPRTDSQYVTEDMKETVKMLAEGMTGFLPFLESGQTRGNIDRVVNNAKVSDHHAILPTKEAMEKGMGGLSSGKKNLLMLIGQQLVQATGEEYLYEQTEISVQCKEHEFAAKGKLSVQMGFKEVEEAFRKYCVKDKKSDEPDNKTELSEGYEEGMILASVKAEKSTHYTSPPKMFTEDTLLAAMETAGNKEFDSETEKKGLGTPATRANIIEKLVSSGYAERKGKQILPTVAGCELIHVMPENLKSASLTAEWENLLLMMEKGKIQEDEFMNGIVSMINEILSLCRAIPEEERNRFQTAREVIGKCPVCGSDVYEGKTNYYCSDRSCQFALWKSNRFLESMKKSMDKKMAVELLKKGRTHVKGLYSKKKDSKFDADLVLGVEEGKARFSLEFPKKKK
(1705) DNA topoisomerase [Ruminococcus obeum A2-162]
7
MGKSLYIAEKPSVAQEFAKALKINGQRRDGYLESEDSVVTWCVGHLVTMSYPEKYDIKYKRWSLDTLPFLPHEFKYEVIPGVQKQFNIVKGLLNRPDVETIYVCTDSGREGEYIYRLVAQMAGVKDKNQRRVWIDSQTEEEILRGIREAKELSAYDNLADSAYLRAKEDYLMGINFSRVLTLRYGNSVSNYLNSRHQAISVGRVMTCVLGMVVRREREIRSFVKTPFYRVLSSIVLEGERFEGEWRAVDGSRYFQSPYLYKENGFKEKKHAEELIGMLQAQQPLSCRVEKVERKKENKNPPLLFNLAELQNVCSKLFKISPDETLRITQELYEKKLVTYPRTDARVLSSAVAKEIYKNISGLRRYPAIDNAAEEILQMGSYKSIAKTRYVNDKQITDHYAIIPTGQGMNALNGLSLTSQRVYETIVRRFLCVFCPPAVYQKVSLTTEMQGEKFFSSFKVLQEEGYLKYATNSFAKKSLAEKETEKNDEEDVSCDSQLLNALQALKKNDILTVDALNIKEGETSPPKRYNSGSMILAMENAGQLIEDEELRAQIKGSGIGTSATRAEILKKLVSIKYLSLNKKTQVITPTLLGEMIFDVVNCSIRSLLNPELTASWEKGLTYVAEGSITPQEYMDKLEHFVRVRTNQVEQSNYQYALRQFFDAAAANYTKKPTTVKRGGKA
(239) DNA topoisomerase [Ruminococcus obeum A2-162]
7
MKLVICEKPSVGAAVAAALGVREKKDGYIEGNGYVISWCIGHLVGLAEAAAYGEQYRKWSYDSLPILPQEWQYTVAADKGKQFKILKDLMQRSDVSEVVNACDAGREGELIFRFVYHQAGCKKPFTRLWISSMETDAIKSGFDNLKDGRRYDALYHSALCRAKADWLIGINATRLFSCLYGKTLNVGRVQTPTLKMLVDRDAAIMNFKKEKYYHVRLMLPGAEAASAKICAADEAGKLKAACEASAAVCTSLTRENKTAIPPKLFDLTSLQREANRIYGYTAKQTFDLAQTLYEKKLLTYPRTDSNYLTDDMGDTAASIVSLLCGKLPFMASAAYEQSISRVLNSKKVSDHHAIIPTMEIAKTDLTTLPESERNILILTGARLLMATAEPHVYEAVTAVFSCADHEFTARGKTVIAAGWKNIERLYRATLKKKPDSDDENELVLDVPDFTEGQTFENPAAKVTEHETTPPKPHNEASLLSAMERAGNEDTDPDAERRGLGTPATRAAVIEKLVKGGFVERKGKQLLPTKDGTSLVCVLPDSLTSPQLTAAWENNLTQIAKGNADPAAFMQGIEAMAQELVKTYASVLGEKQELFKTEKTELGKCPRCKSPVYEGKKNYYCSNKECSFTMWKNDRFFEERKTVFTPKIAAALLKSGKAKVKKLYSVKTGKTYDGTVLLADTGGKYVNYKVTISKDKELE
(415) DNA topoisomerase 3 [Ruminococcus obeum A2-162]
2
MKSLVIAEKPSVARDIARVLHCNQKGNGILEGKEYVVTWALGHLVTLADPEEYDKKYVKWDMETLPMMPEKMKLVVIRQTSKQYQAVKDQLFRKDIGDIIIATDAGREGELVARWILDKSGCRKPIRRLWISSVTDKAIRDGFHNLKGGREYDNLYRAAVARAEADWLVGINGTRALTCRHNAQLSCGRVQTPTLAIIARREEEIRKFQPEEYYGVTLQAGGIQWTWKDTRSGSYRTFQKDRAEDIRKNISDGVLEITSVAKKPKKTYAPGLYDLTTLQREANQKYGFSAKETLNIMQRLYENHKVLTYPRTDSRYIGKDVVPTIKERLKACGTGPYRKLAGVLISKPIQTNGGFVDDKKVSDHHAIIPTEQFVQLDHMTNEERKIYDMVVRRFLSVLYPAFEYEQTSLEAKAAGQTFAANGKTVIRAGWKAVYEEGMQEEDTEDNALKDQKLPVFRQGEKIHIDSVRLTNGKTKPPAHFTEATLLAAMENPVKYMSTKDSQAAKTLGETGGLGTVATRADIIEKLFHTFLMEKRGNEIYLTSKAKQLLELVPEDLKKPELTADWEKKLSDISKGKLKQKVFLDGIREYTEEIVGEIKTGTGTFRHDNLTNKICPNCGKRLLAVNGKNSKMLVCQDRECGYRETISRTTNARCPKCHKRMEMLVKGKEETFVCACGYKEKLSSFQARRAKEGAGVNKRDVQKYLKKQQKEAAEPVNNAFAQALAGIKLD
(1027) DNA topoisomerase 1 [Ruminococcus obeum A2-162]
1
MAKYLVIVESPAKVKTIKKFLGSNYDVQASNGHVRDFPKSQFGIDVENDFEPKYITIRGKGELLANLRKAAKKADKIYLATDPDREGEAISWHLMQALKEDPAKMRRISFNEITKTAVKASIKQPRDLDLNLVDAQQARRMLDRMVGYTISPLLWVKVKRGLSAGRVQSVALRIICDREEEINSFIPEEYWSLDGEFKIKGEKKPLQAKFYGTDKKLPIHNKAEMDKILKALENAQYEITEVKKGERTKNAPLPFTTSTLQQEAAKTLNFSTQKTMRLAQQLYEGIDIKGSGTVGLISYLRTDSTRISQEADQAAREYIEAQYGDNYVSTTGKTVKKEQKIQDAHEAIRPTDITRLPAMIKESLSRDQFRLYQLIWKRFTASRMSAAKYETTSVKIGAGEYTFTVAASKIVFDGFMSVYVQEEDNQKGNVLSQSLEKGMKLELTELKPEQHFTQPPAHYTEASLVKALEEQGIGRPSTYAPTITTIISRRYVSKEQKNLYVTELGEVVNNIMKQAFPSIVDVRFTAMMEGLLDCVEEGTVQWKTVVRNFYPDLKRDVDAAEKELEKVEIQDEVSDEVCDVCGRNMVIKYGPHGRFLACPGFPECRNTKPYYEKIGVACPKCGKDVVLKKTQKGRKYYGCIDNPECDFMSWQKPSAKKCPKCGSYMVEKGNKIVCSETTCGYVEQKSKED
(1210) DNA topoisomerase 1 [Roseburia intestinalis M50/1]
1
MAKYLVIVESPAKVKTIKKFLGKNYEVVASNGHVRDLPKSQMGIDIENDFEPKYITIRGKGDILAKLRKEAKKADKVYLATDPDREGEAISWHLSQALKLDDKNAQRITFNEITQNAVKASLKEPRKIDMNLVDAQQTRRILDRLVGYEISPLLWAKVKRGLSAGRVQSVALRIICDREDEINAFIPEEYWTLDAELSVKGERKTLLAKFYGDENGKLTISSKEQADRIMAEMQKEEFHVLEVKKGERVKKAPLPFTTSTLQQEASKALNFPISKTMRIAQQLYEGVDVKGQGTVGLITYLRTDSVRISEEADAQAREYIAGNYGENYIAGEKTTKKNGAKIQDAHEAIRPSDINRTPVMVKESLSRDQFRLYQLIWKRFTASRMAQAVYETTNVKIGAGEYRFTVSASKIAFDGFMSVYTSDDDEKAENNVLVGSIDENTVLNLKEFDEKQHFTQPPAHYTEASLVKTLEELGIGRPSTYSPTITTLLGRRYIVKEAKNLYVTELGEVVNQIMKESFPSIVDEHFTANMESLLDGVEEGNVNWKTVVRNFYPDLDEAVKAAQKDLEKVKIEDEVTDVICDVCGRNMVVKYGPHGKFLACPGFPECRNTKPYLEKIGVTCPKCGKEVVLRKTKKGRKYFGCEDNPECDFMSWSRPVAEKCPKCGGYMVIKGNKIVCADEQCGYVTDRKNVEKDSE
Family distribution
Taxonomy tree
Lachnospiraceae