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Taxon : Bacillaceae
Informations
Name
Bacillaceae
Rank
family
# topoisomerases
73
Lineage and sub-taxa
Lineage
Bacteria
>
Firmicutes
>
Bacilli
>
Bacillales
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Bacillaceae
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(157) DNA topoisomerase III [Bacillus halodurans C-125]
7
MGAVVVIAEKPDQGMKLAAPFPHRNKRGYVEVAPCDQFPAGAFFTWAVGHLCELCPPEQYDPSWKKWTLEALPLIPQSFVHRVSRGKKDQFQVIRSLVHRKEVTEIVMAGDAGREGELIVRLILKQCRVKKKTSRLWLSSLTKQAVVSGFHQLKSAESTEPLYHEALSRSCADWLIGMNVTRAYTLLLKKKGVDSLFSTGRVQTPTLALIVKREKEIEAFESKPFWEVKATFRVQGHEYEGIWHKDRETRLFDQPMAEAIAAFCRGKQGKVTKVKKETKTLKPPYLFNLSSLQATANKRFTFSPKKTLDVAQKLYVKGHISYPRTDSSFLTAEEGKAAKRIVQLLKQEDAYASLFPLDRDNLLQDRRYVNQSKVTDHYAIIPTDDVPKVQTLAKDEQLLYDLIVRQFLAAHMREAKIAYTEVETLVDERATFLTKGKQLLDQGWKQIIGLSKDDKDEDIPPLEEGWTGDVKHADVREGKTKPPSRYTEGQLITLMKTVGKHVEDDELEKVLMRTEGLGTEATRAGIITLLKDRQYIEIKKNVVYATEKGKLLIEALGPSLLASPEMTAKWEQRLFEIGRGQADAHAFMEQVKKLSDHLVKEAHQRANTWDFSSFDQEALEEKTKKRKKRRPTYVGSCLACDGKLLDRGEFYGCTNYEAKSCRFTISKTILGKRLSQANVKKLLQGETTNVIKGLKKGSDTFDAKLYWDKEKKKLGFQPVES
(1137) DNA topoisomerase 1 [Bacillus halodurans C-125]
1
MADYLVIVESPAKAKTIGKYLGKKYTVKASMGHVRDLPKSQMGVDIEDEYSPRYITIRGKGPVLKELKSAAKKVKRVYLAADPDREGEAIAWHLAHSLDIDETSECRVVFNEITKQAIKDAFKSPRPINMDLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKMIIDREKEIQAFEPEEYWSIQGTFALDGEPFEAKFYGTNGKKVELKSEDDVNNVLAKLKGDQFHVDSVQKKERKRNPVSPFTTSSLQQEAARKLNFRAKKTMMLAQQLYEGIDLGKEGTVGLITYMRTDSTRISDTAKAETKEYIESKFGKEYAQNGTKAVKKDKKSQDAHEAIRPTSVERDPKSLKEYLSRDQLRLYKLIWERLVASQMAPAIMDTMTVDLSNEGVLFRATGSKVKFPGFMKVYIEGNDEGKKEEDRLLPNLQEGQTVTKEEIEPSQHFTQPPPRYTEARLVKTMEELGIGRPSTYAPTLDTIQKRGYVALDERRFVPTELGEIVLELMTEFFPEILDVEFTAKMEDDLDSIEEGKQQWIKIIDDFYKGFEERLKVAEEEMKEVEIKDEPTGEMCEKCGHEMVYKMGRYGKFMACSNFPDCRNTKPIVKEIGVKCPKCEKGEIVERKSKKRRVFYGCNQYPECDFVSWDKPIARSCPKCSSYLVEKRTKKQVQVQCSSCDYKEEAN
(1172) DNA topoisomerase [Bacillus coagulans 36D1]
2
MKSLVLAEKPSVGRELARVLGCTENKKRYIEGPRYIVTWALGHLIELKMPEDYHPKYKEWRMEDLPILPDKMEIKTIRQTYPQYKAIEQLGKRSDIKDCIIATDAGREGELVARWILEKMHWRKPVKRLWISSQTDKAIKDGFKQLKPAKQYDNLYHSAVCRSEADWLIGLNVSRALTVKYNDPLSAGRVQTPTLAMVLEREREIQSFVPKKYWTIEALAGKLEVSYDHHGEKRIFDEQKANAIHAALSGQTAVVTEVIRKQKQEQQPLPYDLTELQRDANHRFGFTAKKTLNVLQNLYEQHKLVTYPRTDSKYLTKDMENMMYDRLLAVKDAYKEEVQPILSRKGKILAKRVINDAKVTDHHAIIPTDERPALSDLSADERKIYDLIVKRFLALFYPVYEYETVQFKLQAGGKTMTGRTMAVKNAGFTAVLHHEQERENTALLSIKEGKKFKLEQIRLSQHLTEAPKRYSEADILSRMEKYGLGTPATRADIIERLVSSETISRESGRLVPTPKGKQLIDLVNDELKSPELTAKWEEQLEAIARGKGNPKQFLETIRRETVRLVREIRTSDKKYRAHNLTGTKCPECGSLMKEVNGKDGKKLVCSNRECRFTKRKSPKLSNRRCPTCHKKMEIHHGKSGVYFQCRHCNIVQKADEKKKTLSKHEEKKLLQKYTKKEESFGNSLADALKAALEKE
(1637) DNA topoisomerase 1 [Bacillus coagulans 36D1]
1
MDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIDRENEIKSFVPEEYWTIAGSFKKGKDTFQASFYGVDGKKIQLKSEADVKKITGMLKSDKFQVSSVTHKEKKRNPAPPFTTSSLQQEAARKLNFRAKKTMMVAQQLYEGIDLGKEGTVGLITYMRTDSTRISEVAKTEANQYIREKFGENYLRQEERKEKKQANAQDAHEGIRPTSIFRDPGSVKSFLSRDQYKLYKLIWERFMASQMAPAILDTMSATLANGTVLFRASGSKIQFPGFMKVYVEGSDDQQEEGERYLPHLEEGDVVQSESIEPKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRGYVALENKRFVPTELGEIVLELIREFFPEIIDVEFTADMEKDLDEIEEGKVPWVQIIDAFYQNFEARLKKAETEMEKIEIKDEETGEMCELCGSPMVYKMGRYGKFMACSNFPDCRNTKPIVKKIGVTCPKCGKGEIIERKTKKNRIFYGCDRYPECDFVSWDKPVGRKCPKCGDMLVEKKLKKGTQIQCVHCDYKEQSVK
(1856) DNA topoisomerase [Bacillus coagulans 36D1]
7
MSFPLIIAEKPDQGRTLCSVFPHVKREGYIEIRPNEIFPEGAFCTWAIGHLTQLVPPEHYNPAWEQWKLETLPILPETFKYEVAKSKYKQFQIVKKLVKDARVTNIIHAGDAGREGELIIRNILHLCGAKKPLRRLWISSLTPQSIREGFRHLLHDEDTRPLYDEAYARACADWLVGMNASRVYSLLLRQKGMRDVFSVGRVQTPTLALIVKRELEIEHFKPEPFWEVTAMFQFDDKQYEGKWVKDGESRLNDPAMAARIAAFCRQKPAEVAELKKEKKEFQPPLLFNLSSLQAAANRAFQFPPKKTLDLVQSLYQKGIVSYPRSDSQYVTKGEAETFPGILEKLSACPEYAPYFPLPKRSILQNKRYVNEKKVSDHYAIIPTEQVVAPGSLPDGEKKIYDMIVRRLIAAHYGNAVFHYTTVKTVVDSRATFLSKGTQMEAEGWRKVIFSKEKEKDGILPDVKQGEKGVVIDTNVKEGKTQPPKRYTEGQLITLMKTAGKYIEDRELEKVMAEVEGLGTEATRAGVITILKDRKYIEVKKNQVYATDKAKVLIRAIGGKILASPEMTAKWEKRLREIGKGAAEAAAFMEQTKKLSRKIVQDAVQAAAEWDFSGLKTDDIKRPESKYTIGKKAGKCPACGGDIVDKGDFYGCSAYRKSGCTFTLSKSILGKKISLANVRKLLAGEETNMIKGFRKNGKTFDAKLKWEDGKLRFIFAKQQTGR
(1713) DNA topoisomerase [Bacillus cellulosilyticus DSM 2522]
7
MKLIIAEKPDQGAKLAAPFSSKKQAGFIEISPNDTFPKGALVTWAVGHLCELVPPDYYHPHWKKWSLKNLPIIPEQFQHRVITSKWKQFNIIKRLIHDQRITEIIIAGDAGREGEAIIRIVLTLCKNSKPMKRLWISSLTKNAVLTGFNHLLDEAETRSLYYEALSRSCADWIVGINASRAYTLLLQQKGIKDIFSIGRVQTPTLALIVQREKEIETFKQEEFWEVVATFHMNNNQYKGKWHKENDSRLKEKELAEKIRRFCVHKEATIQSIEKKRKDFKPPFLLNLSNLQALANKRFKYSPQKTLDIAQKLYTKGIISYPRSDSNFITKEEAKMLPDILFKLSKLEHFEKYFPLQVESILNNKRYVNDKKVSDHYAIIPTEQVTNPTKLQSEESNIYILIVEQLIAAHYKSAIIDYTTIQTLVDNRATFLTKGKEIVQAGWREVLYKNDDKASNDEDQQLPALREGESGHVFDVDIKSGKTQPPKRFTEGELITVMKTAGKALDDKELVHILKNTEGLGTEATRAGIIQVLKDRKYIQVIKNQVFVTEKGKLLVEAVGDSILASPEMTAKWEKRLSEIGEGKAAPKIFIEQAKNLACNVLETANKQVENWDFKNIDISSIESFSSKNKKGRRQTVVGKCKKCDGQIIDKGSFYGCSNYRNTNCSFTLSKILLGKTITQTQVKKLLTKGKTDIIHGFKKNSKTFNASLILNTTTYKLEFKWDN
(1822) DNA topoisomerase 3 [Bacillus cellulosilyticus DSM 2522]
2
MKKSVVIAEKPSVARDIARVLKCNKKGNGFIEGDKYIITWALGHLVTLADPEAYDQKYKSWKIEDLPMIPNHLKLVVIKKTSKQFHAVKSQLHRSDVGDIIIATDAGREGELVARWIIEKAKISKPTKRLWISSVTDKAIKEGFQQLKNAKAYENLYESAVARSEADWYIGLNATRALTCKYNAQLSSGRVQTPTLAIISQREEEIRSFRPKAFYGITAKTEENLSLSWQDKRSKDFRSFSKDNITNILSNIKGNNATVVEVSKKNKKNFAPQLYDLTELQRDANKAFHYSAKETLSIMQRLYEQHKVLTYPRTDSRYISDDIVDTLKDRVIACGKSYSEYSKLANKIVQKPLQANKSFVDNTKVSDHHAIIPTEEVANIAMFSDKERKIYDLVVKRFLAVLSPPFEYEQTTIVAEIASETFIARGKKVNSLGWKEVYGNVIEDEESDDVKEQVIPQIVKGDTLTITKVSQTEGETKPPARFNEATLLSAMENPAKYIVGETKELAKTLEKTGGLGTVATRADIIEKLFNSFLIEKKEKDIHLTSKGKQLLDLVPSDLKSPALTGEWEQKLEAIAKGNLKKNDFINDMKEYAKTVVHEIKNSDKKFKHNNMTGTKCPECGKNMLEVNSKKGKMHICQDRECGHRKNISKVTNARCPKCKKKLELRGQGEGQVFACKCGHKEKLATFNERKKKEKNTKLSKREVNNFMKKQNKQQDDEPFNPALADALAKLKLK
(1364) DNA topoisomerase 1 [Bacillus cellulosilyticus DSM 2522]
1
MSDYLVIVESPAKAKTIGKYLGKKYAVKASMGHVIDLPKSQMGVDVEEGFTPKYITIRGKGPILKDLKAAAKKAKRVYLAADPDREGEAIAWHLAHSLNIDEKSECRVVFNEITKQAIKDSFKRPRTINMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKMIIDREKEINAFEPEEYWSIDAKFEKDGEAFEAKFISKDGEKLSLKSENDVKEVLKALSGESFQIEKVKKRERKRNPVVPFTTSSLQQEAARKLNFRAKKTMMLAQQLYEGIDIGKLGTVGLITYMRTDSTRLSETAKAEAKTYIESHYGKEYVNQQEAKTKQKSNSQDAHEAIRPTSVDLDPKSVKSYLSRDQLRLYKLIWERMVASQMAPAILDTMSVDLVNNGVAFRATGSKLKFAGFMKVYIEGNDDGKKEEDRLLPEMSEGEQAKAEAIDPNQHFTQPPPRYTEARLVKTMEELGIGRPSTYAPTLDTIQRRGYVALEDKRFIPTELGEIVLELIEEFFPEILNVTFTAKMENDLDSIEDGEEEWVKVIDEFYSDFERRLKTAEEEMKEVEIKDEPAGEDCEKCGHEMVYKMGRFGKFMACSNFPDCRNTKAIVKDIGVKCPECKEGNVVERKSKKRRIFYGCDRYPECEFISWDKPIARKCPKCEHMLVEKKTKKGIHVQCSKCDYREDQN
(63) DNA topoisomerase 3 [Bacillus licheniformis DSM 13 = ATCC 14580]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFQAVKSQLIRKDVKDIVIATDAGREGELVARWIIEKAKVTKPLKRLWISSVTDKAIKDGFKNLKNGKDFENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREEDIKNFKPVPYFGLRAAVDGMTLTWQDKKTSQTRTFNASVTSQLAGALQGKPAVIVDLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSNDIVPTLKDRLEGMQVKPYAQHVARILKRGVKANKSFVNDAKVSDHHAIIPTEEPLALGALSEKERKLYDLIAKRFLAVLMPPFEYEETKVFAEIGGETFTAKGKTVQSQGWKAVYDFADEDDDEEEKDQTLPKLAKGDTLSVRSLTETKGETKPPARFNEGTLLSAMENPAAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNTFLIEKKGKDIYITSKGKQLLELVPSDLKSPALTAEWEQKLSGIAKGKLKSSAFIKEMKEYAKQTIREIKSSNQKFKHDNITGTHCPDCGKLMLKVNGKRGTMLVCQDRECGHRKTVAKQTNARCPVCHKRMELRGHGEGQTFACVCGHREKLSVFEKRRAKDKNSKASKRDVHSYMKKQNKDEPINNALAEQLKKLKLDQ
(1156) DNA topoisomerase 1 [Bacillus licheniformis DSM 13 = ATCC 14580]
1
MSEYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLNSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREKEINDFIPEEYWTIEGSFLKGKETFEASFFGINGEKHQLKSEDDVKQILSRIKGNKFEVKKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISNTAQEEAASFIGEQYGKEFLGSKRKPAKKNENAQDAHEAIRPTSVLRKPSDLKAVLGRDQLRLYKLIWERFVASQMAPATLDTMSVDLENNGLTFRANGSKVKFSGFMKVYVEGKDDQMEEKNKMLPDLAEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRGYVALDNKRFIPTELGEIVLDLIMEFFPEIINVEFTAKMEKELDDVEDGNIQWVQIIDSFYKDFEKRVEKAEAEMQEVEIEPEYAGVDCEACGHPMVYKMGRYGKFMACSNFPDCRNTKPIVKEIGVKCPSCKTGNIVERKSKKRRIFYGCDRYPECEFVSWDKPLERKCPKCEDMLVEKKLKKGVQVQCVNCDYKEEQQK
(1157) DNA topoisomerase 1 [Bacillus licheniformis DSM 13 = ATCC 14580]
1
MSEYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLNSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREKEINDFIPEEYWTIEGSFLKGKETFEASFFGINGEKHQLKSEDDVKQILSRIKGNKFEVKKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISNTAQEEAASFIGEQYGKEFLGSKRKPAKKNENAQDAHEAIRPTSVLRKPSDLKAVLGRDQLRLYKLIWERFVASQMAPATLDTMSVDLENNGLTFRANGSKVKFSGFMKVYVEGKDDQMEEKNKMLPDLAEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRGYVALDNKRFIPTELGEIVLDLIMEFFPEIINVEFTAKMEKELDDVEDGNIQWVQIIDSFYKDFEKRVEKAEAEMQEVEIEPEYAGVDCEACGHPMVYKMGRYGKFMACSNFPDCRNTKPIVKEIGVKCPSCKTGNIVERKSKKRRIFYGCDRYPECEFVSWDKPLERKCPKCEDMLVEKKLKKGVQVQCVNCDYKEEQQK
(62) DNA topoisomerase 3 [Bacillus licheniformis DSM 13 = ATCC 14580]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFQAVKSQLIRKDVKDIVIATDAGREGELVARWIIEKAKVTKPLKRLWISSVTDKAIKDGFKNLKNGKDFENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREEDIKNFKPVPYFGLRAAVDGMTLTWQDKKTSQTRTFNASVTSQLAGALQGKPAVIVDLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSNDIVPTLKDRLEGMQVKPYAQHVARILKRGVKANKSFVNDAKVSDHHAIIPTEEPLALGALSEKERKLYDLIAKRFLAVLMPPFEYEETKVFAEIGGETFTAKGKTVQSQGWKAVYDFADEDDDEEEKDQTLPKLAKGDTLSVRSLTETKGETKPPARFNEGTLLSAMENPAAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNTFLIEKKGKDIYITSKGKQLLELVPSDLKSPALTAEWEQKLSGIAKGKLKSSAFIKEMKEYAKQTIREIKSSNQKFKHDNITGTHCPDCGKLMLKVNGKRGTMLVCQDRECGHRKTVAKQTNARCPVCHKRMELRGHGEGQTFACVCGHREKLSVFEKRRAKDKNSKASKRDVHSYMKKQNKDEPINNALAEQLKKLKLDQ
(1429) DNA topoisomerase 3 [Bacillus subtilis subsp. spizizenii TU-B-10]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDQYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKSQLTRKDVNQIVIATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGIRAAVDGMTLTWQDKKSKQTRTFNQDVTSRLLKDLEGKQAVIAELKKTAKKSFAPALYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSSDIVPTLKDRLEGMEVKPYAQYVSQIKKRGIKSHKGYVNDAKVSDHHAIIPTEEPLVLSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVIAEIGGETFTAKGKTVQSQGWKAVYDMADEDDEQEDDRDQTLPALQKGDALTVRMLTETNGQTKPPARFNEGTLLSAMENPSAFMQGEEKGLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKDKDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSAIAAGKLKSSVFIKDMKAYANQTVKEIKNSSQTFRHDNVTGTACPECGKMMLKVNGKRGTMLVCQDRECGSRKTIARKTNARCPNCHKKMELRGQGEGQTFACVCGHREKLSVFEKRKNKDKGRASKRDVSSYMKKQNNKEEPINNALAEQLKKLGLDK
(791) DNA topoisomerase 1 [Bacillus subtilis subsp. spizizenii TU-B-10]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLNSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREKEINDFKPEEYWTIDGTFLKGQETFEASFFGKNGKKLPLKSEADVKDILSQLKGNKYTVEKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGREGTVGLITYMRTDSTRISNTAVDEAAAFIDQAYGKEFLGGKRKPAKKNENAQDAHEAIRPTSVLRKPSELKAVLGRDQMRLYKLIWERFVASQMAPAVLDTMSVDLTNNGLTFRANGSKVKFSGFMKVYVEGKDDQMEEKDRMLPDLQEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQRRGYVGLDNKRFVPTELGQIVLELIMEFFPEIINVEFTAKMEKDLDNVEEGNIEWVQIIDNFYTDFEKRVKKAESEMKEVEIEPEYAGEDCELCSSPMVYKMGRYGKFLACSNFPDCRNTKPIVKQIGVKCPSCGEGNIVERKSKKKRVFYGCDRYPDCEFVSWDKPIERKCPKCGKMLVEKKLKKGIQVQCVECDYKEEPQK
(533) DNA topoisomerase 1 [Bacillus anthracis str. CDC 684]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(895) DNA topoisomerase [Bacillus anthracis str. CDC 684]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDESDTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYDGKWEKDNESRLQDPDMANKIAAFCQGKPAVVKEMKTERKEFQPPLLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPVESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSRLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTIVTLVDERAEFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEEGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGSCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKTISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(12) DNA topoisomerase 3 [Bacillus anthracis str. CDC 684]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(295) DNA topoisomerase 1 [Bacillus weihenstephanensis KBAB4]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKYPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREKEIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNEAQVNEIIEKMKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARDYITEAFGAEYIGTEKRKETKKSKAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTAKLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDIEPKQHYTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVALDNKRFVPTELGGIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCSHPMVFKMGKYGKFMACSNFPECRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(222) DNA topoisomerase [Bacillus weihenstephanensis KBAB4]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLNTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDEADTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYEGKWEKDNESRLNDPDLANKIAAFCQNKPAVVKEMKTERKEFQPPFLFNLSALQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPIESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSKLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTITTLVDERAAFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEQGKVGKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVQKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGNCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKAISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(577) DNA topoisomerase 3 [Bacillus weihenstephanensis KBAB4]
2
MAKSIVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKQWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIIATDAGREGELVARWIIDKVKMQKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKHFKAQTYYGIEAQTAERLKLTWQDTKGNSRSFNKEKTDAIVNKISKQNATVVDIDKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPVKSNKSFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFIARGKTILHAGWKEVYENRFEDDDASDDVKEQILPRIEKGDTLNIKLIVQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLLEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVAEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGSKADKRDVQKYMKQQNKEEEPLNNPFAEALKKLKFD
(940) DNA topoisomerase 1 [Bacillus pseudomycoides DSM 12442]
1
MESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIDREKEIQSFIPEEFWTIKTEFVKGKDTFEASFYGVNGEKVQLTNEAQVKDIIETMKNNAFSVENVTKKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDIGKQGTVGLITYMRTDSTRISETAQEEARSYITEAFGSEYIGTEKKKETKKANAQDAHEAIRPTSVMRKPEELKSFLSRDQHRLYKLIWERFVASQMASAVMDTVTARLINNNVQFRASGSVVKFSGFMKVYVESKDDGAEEKDKMLPPLEIGETVFSKDMDPKQHFTQPPPRYTEARLVRMLEELGIGRPSTYVPTLETIQKRGYVALDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQNLDEVEEGKANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCGHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(1583) DNA topoisomerase [Bacillus pseudomycoides DSM 12442]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTGIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDEADTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYEGKWEKDNESRLKDPDMANKIAAFCQNKPAEVKEMKTERKEFQPPFLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFEEYKDLLPAPIESIMNNKRYVNEKKVTDHYAIIPTEQATNPNKLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTITTLVDSRAEFISKGKQQIQEGWRKVIFQDDKEDETILPIVVEGEQGKVVTVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGIASPATFMEQTKKLSAKIIEDAIEMSEKWDFTGLHVESIERKESKFTTGKKVGKCKKCDGDIIDKSTFYGCSNYNTTQCDFTISKKILGKTISQKNMTKLLKGEQTDLIKGFKKNDKTFDAKLEWKENKINFVFEK
(1608) DNA topoisomerase 3 [Bacillus pseudomycoides DSM 12442]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGNKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLIRKDVTEIIVATDAGREGELVARWIIDKVKINKPIKRLWISSVTDKAIKDGFANLKPGKAYENLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAIIAGREDEIKNFKAQTYYGIEAQTTDKLKLTWQDGKGNGRSFDKAKIDTIVKKLDKQNATVTEIEKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKILNKPIKSTKAFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFVARGKTILHSGWKEVYENRFEDDDAVEDLKEQILPRIEKGDTLSVKLIAQTSGQTKPPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTAEWEQKLEAIAKGKLKKEIFISEMKNYTKEIVAEIKSSDKKYKHENISTKTCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGDGQIFACKCGYREKLSTFQERRKKESGNKADKRYVQKYMKQQQKEEEEPLNNALAEALKKLKFE
(990) DNA topoisomerase [Geobacillus thermoglucosidasius C56-YS93]
7
MKVIIAEKPDQGATLASIFQTKKHQGYIEIYPNELFPKGAYMTWAVGHLFQLVPPEWYRPEWKQWKLETLPIIPERFQYEVERAKAKQFAIVKELLRKPEVTEIIHAGDAGREGELIVRNIIHMSGVKKPMKRLWLSSLTPKAIYEGFRQLLDEAETRNLYEEAYARACADWLVGMNASRVYSILLKQKGMNDVFSVGRVQTPTLAFIVKREKEIEQFRPEPFWEVVAAFAVNGKQYEGKWTNEEGETRIKEEQLAQKIAQFCRNKLAEIHEVKTERKTFLPPLLFNLSSLQATANKMYQFSPKKTLDILQNLYQKGIVSYPRSDSNYVTKGEAETFPDILQKLRAFSDYQPFFPLPNALILHNKRYVNEKKVTDHYAIIPTEQVVDPAKLPADERKIYDLIVRRLIAAHYEAAVFDFTTVITLVDGRARFVSKGKQQIQEGWRKVISPREDDDGALLPLLHEGEQGDVLNVRVKVGKTQPPKRYTEGQLITLMKTAGKFLDNEELEKVLAKTEGLGTEATRAAIITTLKERNYIEVRKNQVYATDKAKVLIEAIGDKILASPEMTAKWEQRLSEIGEGKASAAQFMEQVKKLSAKIVQDAVEMSETWDFAGLDTASIQRTTSKAALGKPVGPCKLCGGTVIDKGAFYGCANYAKTKCPFAISKKILGKTVSRANVKKLLEHGRTGVIKGFKKEGKTFDAALVWDEKEKKITFSFAKK
(1342) DNA topoisomerase 1 [Geobacillus thermoglucosidasius C56-YS93]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDINNGYEPKYITIRGKGQIIKELKTAAKKAKKVFLAADPDREGEAIAWHLANMLELDIHSDCRVVFNEITKDAIKESFQHPRAIDMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREKEIKQFQPEEYWTIQAEFVKGNETFTASFYGADGQKLDLKNEADVSAILRRINGNHFTVTSVAKKERKRNPVPPFTTSSLQQEAARKLNFRTKKTMMIAQQLYEGIDLGSEGTVGLITYMRTDSTRVSESAQQEALSYIEATFGKEFAAQEKRKEKKSANAQDAHEAIRPTSVFRDPEKVKPYLTRDQFRLYKLIWERFVASQMAAALLDTMSVELENGGVIFRANGSKVKFPGFMKVYVEGTDDQTDEQDRLLPDLQEGETVFSKDIEPKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTIDTIQKRNYVVLENKRFVPTELGEIVVELILEFFPEIIDVEFTAKMEKNLDEIEEGKVQWVKVVDEFYREFEKRLQIAEKEMKEVEIKDEPAGVDCEVCGSPMVYKMGRFGKFVACSNFPECRNTKPIVKEIGVKCPKCHEGNIVERSSKKKRIFYGCDRFPQCDFVSWDKPLARRCPKCEGVLVEKKLKKGVQVQCTSCDYEEEPQS
(1299) DNA topoisomerase 1 [Geobacillus thermoleovorans CCB_US3_UF5]
1
MSDYLVIVESPTKAKTIERYLGKKYTVKASMGHVRDLPKSQMGVDIDHGYEPKYITIRGKGQVIKELKTAAKKAKKVFLAADPDREGEAIAWHLAHMLDLDIHSDCRVVFHEITKDAIQQSFQQPRAINMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREREIREFQPEEYWTIQATFQKEGETFAASFYSIDGQKRDLKTEADVKAVLDRLNGTAFAVKTVTKRERKRSPVPPFTTSSLQQEAARKLNFRTKKTMMIAQQLYEGIDLGSEGTVGLITYMRTDSTRVAETAQQEAAAYIEATFGAMYVNQEKRKEKKSTNAQDAHEAIRPTSAFRDPDKVKPYLTRDQFRLYKLIWERFIASQMAAAVLDTMSVELENNGVVFRASGSKVKFPGFMKVYIEGTDDQTEEQDRILPDLEEEETVESETIESKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRNYVVLENKRFVPTELGEIVVELMLEFFPEIIDVEFTAKMEKELDEIEEGKVEWIKVVDEFYREFEKRLKVAEKEMRAVEIKDEPAGIDCEVCGSPMVYKMGRFGKFIACSNFPECRHTKPIVKEIGVKCPKCREGNIVERSTKRKRVFYGCDRFPDCDFVSWDKPLARPCPKCAGLLVEKVLKKGVQVQCTACDYEERLEA
(1063) DNA topoisomerase [Geobacillus thermoleovorans CCB_US3_UF5]
7
MKVIIAEKPDQGATLASIFRTKKRQGYIEILPNDLFPDGAYMTWAIGHLFQLAPPERYRPEWKRWTLNTLPIIPERFEYEIEKAKAKQFQVVKELLRKPEVTEIIHAGDAGREGELIVRNLIRLSGVNKPMKRLWLSSLTPKAIEEGFRRLLDEQTTRPLYEEAYARACADWLVGMNASRVYSLLLKERGMNDVFSVGRVQTPTLALIVRREREIEQFRPEPFWEVVASFVIGDKRYEGKWTDKNGQTRLGDEEMAKKIAAFCQGKRAEVADVRTERKTYQPPLLFNLSTLQATANKLYRFSPKKTLDVLQSLYQKGIVSYPRSDSMHVTKGEAETFPAILQKLSSFPAYAPYFPLPQPSILQNKRYVNEKKVTDHYAIIPTEQVVAPEKLSDDERKVYDLVVRRLIAAHHQAAVIDYTTVTTLVDGRARFVSKGRQVVEEGWRAVIRPHEEEKDAALPPLERGEAGKAAAVKVKEGKTEPPKRYTEGELITLMKTAGKFLDDEELEKVLAKTEGLGTEATRAAIITMLKERKYIEVKKNLVYATDKAKVLIEALGGTILASPEMTAKWEQRLSEIGEGSASPAAFMEQVKKLAQKVVADAIAAAPNWNFRGVDTASIQRTRKKKTMGEKLGPCPLCGGTVIDKGTLYGCDQYAKTKCSFTISKRILGKSISAANVKKLLAQGKTNVIKGFKKGGKTFDAILVWDENEKKLSFQFPKR
(1298) DNA topoisomerase [Geobacillus thermoleovorans CCB_US3_UF5]
7
MKSLVLAEKPSVARDIARVLGCKQAHKHYFEGKQHIVTWALGHLVELKMPEDYDRKYETWRLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRPDVKDVIIATDAGREGELVARWILEMIGWTKPIWRLWISSQTDRAIRDGFRQLKPGAQFDRLYQSAVCRAEADWLIGLNVSRALTTKYNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIRAKIGSITAVWERHGGHRLFDQDEAKQLIARLDGQPARVVSVKRKRKSEPAPLPYDLTELQRDANKRFGFSAKKTLSVLQRLYEQHKLVTYPRTDSRYLPSDMEATMTERLLAMKSGYEDVIAPLLAKGKAKAAKRVFNDDKVTDHHAIVPTDERLNLSRLSTDERKLYDLIARRFLALFFPPYESETTTAVFDIGGEMFVAKETAVVNFGFKAVLGKEETDAKPTLSHLAEGQTLPSVQLEREQSFTEPPARYSEADLLAQMEKYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEELKSPELTARWERELEAIARGKGNPQQFLANIRRQTETLVAEIKQSEQVYKAPNLTNLTCPECGALLKERKTKDGRMLVCSNLACRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGMYFQCRPCNIVEKADETKRIAAKGSERALLKKYSPANESFGTSLGELLKQALNEKKE
(558) DNA topoisomerase 1 [Bacillus thuringiensis serovar konkukian str. 97-27]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEIEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(1090) DNA topoisomerase 3 [Bacillus thuringiensis serovar konkukian str. 97-27]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(233) DNA topoisomerase 1 [Bacillus cereus ATCC 10987]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMNLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIERLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAFGTEYIGTEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(828) DNA topoisomerase 3 [Bacillus cereus ATCC 10987]
2
MSKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGRAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVMEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSKFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(1809) DNA topoisomerase 1 [Geobacillus sp. WCH70]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDINNGYEPKYITIRGKGPIIKELKTAAKKAKKVFLAADPDREGEAIAWHLANMLDLDIHSDCRVVFNEITKDAVKESFQHPRPINMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREKEIKQFQPEEYWTIQAEFVKGNETFTASFYGVDGQKLELKKEADVAAILQRINGNHFTVTSVAKKERKRNPVPPFTTSSLQQEAARKLNFRTKKTMMIAQQLYEGIDLGSEGTVGLITYMRTDSTRVSESARQEALSYIEATFGKEFVAQEKRKEKKNANAQDAHEAIRPTSAFREPEKVKPYLTRDQFRLYKLIWERFIASQMAAALLDTMSIELENEGVIFRASGSKVKFPGFMKVYVEGTDDQTDEQDRLLPDLQEGETVFSKDIEPKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRNYVVLENKRFVPTELGEIVLELMLEFFPEIIDVEFTAKMEKNLDEIEEGKVEWVKVVDEFYQEFEKRLQTAEKEMKEVEIKDEPAGVDCEVCGSPMVYKMGRFGKFVACSNFPECRNTKPIVKEIGVKCPKCREGNIVERSSKKKRIFYGCDRFPQCDFVSWDKPLARPCPKCGGLLVEKKLKKGVQVQCTACDYEEAPQS
(860) DNA topoisomerase 1 [Oceanobacillus iheyensis HTE831]
1
MSDYLVIVESPAKAKTIERYLGKKYTVKASMGHIRDLPKSQTGVDVENNFTPKYITIRGKGDVLKELRKAAKKAKKIYLAADPDREGEAIAWHLAYILGVDPSSNCRVVFNEITKEAIKESFKHPRAIDLDLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALKMIIDREKEIQNFKPEEYWSIDAKFQKDKEIFDGSFYGINGKKVALKNEQDVKDIKQQLNGKKFAVDKVKKRERKKNPALPFTTSSLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKKSGGITGLITYMRTDSTRISNTAKDEAKNYIVDNYGEKYLGKQASTKNKEGAQDAHEAIRPTSALRDPKNLKNILSRDQFRLYKLIWERFVASQMAPAVMDTMTVHLLNNNIEFRATGSKIKFKGFMKVYVEGNDDNKKTEDKLLPELEEGMEVDSKEIKPNQHFTQPPPRYTDARLVRTMEEIGIGRPSTYAPTLDTIQRRGYVTMDNKRFIPTELGEIKCDLMIEFFPEVVDADFTAKMEDDLDSIEEGNIEWKQIIDSFYKDFKVRLDKAEDEMEKVEIKDEPAGIDCENCGHEMVYKMGRYGKFLACSNFPECRNTKPILKEIGVDCPKCEEGNVVERKSKKKRTFYGCDRFPECDFVSWDKPIARKCPKCESMLVEKKNKKETQVQCTNCEYKEVAQT
(400) DNA topoisomerase 3 [Oceanobacillus iheyensis HTE831]
2
MSKTVVLAEKPSVGRDIAKVLGCHKKGNGFLEGSKYIVTWALGHLVTLADPDMYDSKYKTWRMEDLPMLPDHLKLVVMKKTGKQFQSVKTQLNRQDVVEIVIATDAGREGELVARWIIEKARVKKPIKRLWISSVTEKAIKDGFKQLKPGKNYWNLYQSAVARSEADWYVGLNATRALTTKHNAQLSSGRVQTPTLEMVSLREQEIKNFQPKKFYQLEAKTTKGHRFLWKNDENQNRIFSKNEAIKLEEKLSNKQATVVHVDKKLKKKHAQGLYDLTDLQRDANRIFQFSGKQTLSVMQKLYEQHKLVTYPRTDSRHLSTDIVSTLKDRVKACGVDEYAKIANTILNKELRLNKSVVDNAKVTDHHAIIPTEVPVVWTALDDKEKKIYHLIVQRFLAALSDPMEYEQTTITIDIAGEQFIANGKVTKRLGWKEIYKHNDEEDEIQPLNVTKGSKLTLKVELKEGETKPPERFTEGTILQAMENPTRYMGTNKKELVDTIKETGGIGTVATRADIIEKLFMNSYIELKGRNIYLTQTGRQLLDLAPEELRSPLLTAEWEQKLSLIAEGKLKKDQFIKEIKSYTKEAVTEIKQSSETFKHDNMTGTKCPKCGKLMLEIKNKHGKKLVCQDRSCGGKKNIAKFTNARCPNCHKRLELRGEGEGQIFTCKCGHREKLSTFQARKEKEKKQRVSKKDVKKYLNKQDEGFKNNALADALAKLKNDE
(657) DNA topoisomerase 1 [Bacillus atrophaeus 1942]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLNSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREKEINEFKPEEYWTIDGSFLKGQETFEASFFGKGGKKLPLKSEADVKEILSQLKGNKYTVEKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISNTAVEEAAAFIDQTYGKEFLGGKRKPAKKNENAQDAHEAIRPTSILRKPNELKTVLGRDQLRLYKLIWERFVASQMASAVLDTMSVDLENNGLTFRATGSKVKFSGFMKVYVEGKDDQLEEKDRMLPDLQEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQRRGYVGLDNKRFVPTELGQIVLELIMEFFPEIINVEFTARMEQDLDNVEDGNTEWVQIIDRFYTDFEKRVKKAEAEMKEVEIEPEYAGEDCELCSSPMVYKMGRYGKFLACSNFPDCRNTKPIVKQIGVKCPKCEEGNIVERKSKKKRVFYGCDRYPQCDFVSWDKPIERKCPKCGKMLVEKKLKKGIQVQCVECDYKEEPQK
(1155) DNA topoisomerase 3 [Bacillus atrophaeus 1942]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKAQLTRKDVSGIVIATDAGREGELVARWIIEKAHVNKPIKRLWISSVTDKAIKDGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYFGIRAAVEGMTLTWQDKKTKQSRTFDQAVTSRLLDKLEGKSATIADLKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFISNDIVPTLKDRLEGMEVKPYALYVTKILKRGVKAHKGFVNDAKVSDHHAIIPTEEPLIPSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVIADIGGETFTAKGKTVQSQGWKAVYDAYDEEDDQDEDRDQTLPALQKGDSLPVRALKETSGQTKPPARFNEGTLLSAMENPSAFMRGDEKNLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKDKDIFITSKGKQLLQLVPEDLKSPALTGEWEQKLSAIAAGKLKSSVFIKEMKAYANETVKDIKNSSQTFRHDNVTGTACPECGKMMLKVNGKRGTMLVCQDRECGSRKTIARKTNARCPNCHKKLELRGQGEGQIFACVCGHREKLSVFEKRKSKEKTGRASKRDVSSYLKQQNKDEPINNALAEQLKKLGLDK
(311) DNA topoisomerase 3 [Bacillus clausii KSM-K16]
2
MKKKAVLAEKPSVARDIARVLGCNQKGNGYLEGNGYIITWALGHLVTHADPEHYGKQYKTWKLEELPMLPKRLELVVIKQTAKQFHAVKHVLNRQDVGEVVIATDAGREGELVARWILEKAHVKKPVKRLWISSVTDKAIKDGFKQLKDGKRYETLYAAAAARAEADWYVGINGTRALTTKHNAQLSCGRVQTPTLAILADREEAIRKFVPKPYHTISVETKDGVTFRWADRRSKEERIFDDKRAKTLQEKLQQSAIVIDSVNAKTKRTPPPPLYDLTELQREANKRFGYSAKETLAALQRLYEQHKAVTYPRTDSRYLSSDLVETLKERLHAVDVQPFRKMVANAKKQGLANAKRQMVNDAKVSDHHALIPTEQPQSASAMSDKEAKLYHLIVRRFLANFFPPSESELTSVEATANGELLRAKGERLVSAGWRGQETGEEDEALARLLPAMSKGDKKAVKWVGMTQGKTSPPPRFNEGTLLAAMEKPAQHMEAKDETIKKTLAQAGGIGTVATRADIIEKLFSSFYIEKKGKDLYITSKGKQLLELVPAELKSPALTAEWEQRLEKIVQGKEQKQMFIAEMKEYAKAVVAQVKADTATFRHDNKTGEKCPECGKFLLEVNGKKGKMRVCQDRECGYRKNIAMTTNARCPKCKKKLELRGEGEGQVFACVCGHREKKAQFEQRRKQNKHKNVSKREVQSYMKKQNKQDQFANSALADQLAKLGLKGDDS
(1709) DNA topoisomerase 1 [Bacillus clausii KSM-K16]
1
MSDYLVIVESPAKAKTIGKYLGKKYVVKASMGHVRDLPKSQMGVSVEDNYEPRYITIRGKGPVLKELKTAAKKAKRVYLAADPDREGEAIAWHLAHSLNIDENSDCRVVFNEITKTAIKDAFKHPRPINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKLITDREKEIQQFVPEEYWSITGTFLLGDEPFEAKFYGRNGKKESLTSEENVNEVLKQIKGKQFAVADVVKKERRRNPVSPFTTSSLQQEAARKLNFRAKKTMLIAQQLYEGIDLGKEGTVGLITYMRTDSTRISDTAKQETYEYIRSTYGEEYARKGERKQKQDKNAQDAHEAIRPTSVKYEPKQLKEYLSRDQLRLYRLIWERLVASEMAPAIMDTMTVDLENNGVKFRANGSKVKFPGFMKVYIEGNDDNKKEEDRLLPALAKGQQVEKTEVTPNQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQRRGYVALDEKRFVPTELGEIVLDLIVEFFPEILDVEFTAKMEEDLDSIEDGRDNWISIIDQFYQSFEKRLKVAEEEMEEVEIKDEPAGEDCEKCGHEMVYKMGRYGKFMACSNFPECRNTKAIVKEIGVTCPTCKQGNIVERKSKKRRIFYGCDRYPDCEFVSWDKPISRPCPKCQGLLVEKKSKKGVFVACTSCDYEEEKQ
(869) DNA topoisomerase 1 [Bacillus amyloliquefaciens LL3]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLSSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDREKEINDFKPEEYWTITGSFLKGKETFEAGFFGKNGKKLPLKSEEDVKAVLAELKGNKYTVDKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISNTAVEEASAFIDQAYGKEYLAGKRKAAKKNENAQDAHEAIRPTSVLRKPAELKAVLGRDQLRLYKLIWERFVASQMAPAVLDTMSVDLSNNGLTFRANGSKVKFAGFMKVYVEGKDDQLEEKDRMLPDLKEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQRRGYVALDNKRFVPTELGQIVLDLIMEFFPEIINVEFTAKMERDLDHVEDGETEWVQIIDSFYTDFEKRVKKAEAEMKEVEIEPEYADEDCELCGSRMVYKMGRYGKFMACSNFPDCRNTKPIVKQIGVKCPKCHEGNIVERKSKKKRVFYGCDRYPECDFVSWDKPIERKCPKCENMLVEKKLKKGIQVQCVECDYKEEPQK
(1431) DNA topoisomerase 3 [Bacillus amyloliquefaciens LL3]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEYQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKAQLIRKDVSEIVIATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGLRAAADQMTLTWQDKKTKQTRTFDQTVTGRLAKDLQGKPAVISELKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSADIVPTLKDRLNGMEVKPYAQYVNQILKRGVKAHKGFVNDAKVSDHHAIIPTEEPLILSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVTADIGGETFTAKGKTVQSPGWKAVYDMYEDDDDHEEDKDQTLPALQQGQRLSVSSLKETSGQTKPPARFNEGTLLSVMENPSAFMQGEEKNLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKEKDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSSIAAGKLKSAVFIKDMKSYAGKTVKEIKNSSQTFRHDNISGTACPDCGKMMLKVNGKRGTMLVCQDRECGSRKTVARKTNARCPNCHKKMELRGQGEGQTFACVCGHREKLSVFEKRKAKDKSGRASKRDINSYMKKQNNDEPMNNALAEQLKKLGLDK
(428) DNA topoisomerase 3 [Bacillus mycoides DSM 2048]
2
MFLNMAKSIVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKQWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIIATDAGREGELVARWIIDKVKMQKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKHFKAQTYYGIEAQTAERLKLTWQDTKGNSRSFNKEKTDAIVNKISKQNATVVDIDKKQKKSFAPGLYDLTELQRDANKIFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPVKSNKSFVDDSKVSDHHAIIPTESYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKIGDETFIARGKTILHAGWKEVYANRFEDDDASDDVKEQILPRIEKGDTLNIKLIVQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLLEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVAEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGSKADKRDVQKYMKQQNKEEEPLNNPFAEALKKLKFD
(953) DNA topoisomerase [Bacillus mycoides DSM 2048]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLNTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDEADTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYEGKWEKDNESRLNDPDLANKIAAFCQNKPAVVKEMKTERKEFQPPFLFNLSALQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLNQFDEYKGLLPAPIESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSKLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTITTLVDERAAFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEQGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVQKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGNCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKAISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(963) DNA topoisomerase 1 [Bacillus mycoides DSM 2048]
1
MGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKYPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREKEIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNEAQVNEIIEKMKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARDYITEAFGAEYIGTEKRKETKKSKAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTAKLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDIEPKQHYTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVALDNKRFVPTELGGIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCSHPMVFKMGKYGKFMACSNFPECRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(501) DNA topoisomerase 1 [Bacillus pseudofirmus OF4]
1
MADYLVIVESPAKAKTIGKYLGKKYIVKASMGHVRDLPKSQMGVDVEENFQPKYITIRGKGPVLKELKTAAKKVKRIYLAADPDREGEAIAWHLAHSLNIDEQSDCRVVFNEITKQAIKDAFKTPRKINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKMIIEREKEIQAFVPEEYWTIQGKFSLGDEAFDAKFYGVDGKKQELKSEEEVQAVLKQLKGKSFDVASVKKKERKRNPVTPFTTSSLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISETAQNETRQYIVEQFGEEYTRVGQRAVKKDKKAQDAHEAIRPTAVFKDPKSLKSYLSRDQLRLYRLIWERLVASEMAPAIMDTMSVDLVNEGVLFRATGSKVKFPGFMKVYIEGNDDGKKEEDRLLPNLEEGQKVKKESIDPNQHFTQPPPRYTEARLVKTMEELGIGRPSTYAPTLDTIQKRGYVALEEKRFVPTELGEIVLELIVEFFPEILDVEFTAKMEGDLDSIEEGNHEWVHIIDGFYQGFEKRLKVAEEEMKEVEIKDEPAGEDCEKCGHEMVYKMGRYGKFMACSNFPECRNTKAIVKDIGVKCPTCKEGNIVERKSKKRRTFYGCDRYPECEFISWDKPISRPCPKCSAMLVEKKTKKGVNVQCSSCDYKEEAN
(1642) DNA topoisomerase III [Bacillus pseudofirmus OF4]
7
MKLIIAEKPDQGAKLAAPFPMVKKQGYIEIKSCEMFPEGAFVTWAVGHLCELESPEKYDPKWKSWKLDTLPILPPTFKYKVSKGKYKQFQVVKKLIENRNVREIIMAGDAGREGELIVRLIIEQCRASHPLKRLWLSSLTRQAVIDGFNTLKPEQETRPLYDEALSRACADWLIGMNASRAYTLLLGEKGIDDVFSTGRVQTPTLALIVKREKEIEAFKPEPFWEVKAAFKMGEKTYEGVWHKKGETRVNSSRQALQIAQFCEGKPAIVQAIKEEKKEYAPPYLYNLSSLQTAANKRYKYSPKKTLDLAQKLYVKGYISYPRTDSSFVTKGEASTFPAILQKLSAFKEYESFFPLPVKSLMNNRRFVNDQKVSDHYAIIPTEQVPKQERLGAEERNIYDLIVRSLLAAHENAAIISHTQVETIVDGRATFQSKGKQMINEGWRKIIYEGKKQEDTLLPPLSHGEEGVVSKSVVKEGMTQPPKRYTEGQLITVMKAAGKSIEDKELEKVMMESHGLGTEATRAGIITVLKDRGYMMVEKNIVFPTQKGRLLIDSLGTSILASAEMTAKWEQRLREIGKGAASKNDFMEQARKLSVHLINEAVSQSRSWDFTNIDTSSIKRRGGKGSKSYTGNRQVKKTVGQCRLCQGEILDRGTFFGCSNYKSKKCMFTLSKTLLGKKLTETTVTTLLSKGETRVLKGFKKGEQTFDAALRLTPEGKITFQKKE
(931) DNA topoisomerase 3 [Bacillus pseudofirmus OF4]
2
MKKSVVLAEKPSVARDLARVLKCEKKGNGYFEGSKYIVTWALGHLVTLADPESYGDTYKSWKLEDLPMLPSKLNLVVIKKTSKQFHAVKAQLNRGDVEQVIIATDAGREGELVARWILAKAHCHKPVKRLWISSVTDKAIQEGFSQLKDGKRYEPLYDAAVARSEADWYVGLNGTRALTTKYNAQLSCGRVQTPTLAMIAKREADIQAFKPKSFDQLFITVKDSLRFQWYQKESGERRIFDDQHAKNLKEKLEGEKLTVKAVKKQKKKTLAPKLYDLTELQREANQKFGFSAKETLSTLQKLYEHHKAVTYPRTDSRYLSSDLVETLDDRLKACDVQPYRKFVSDIRKRPLKANTHFVDDRKVTDHHAIIPTEQAPAPSALSEREYKLYQLIVRRFLAVLYPAYEYEQTKIEAEACGEQFEAKGDQVLKLGWKVVYDTKEESEGLPVVKEAEEFTIKNCTLTKGETKPPARFNEGTLLSVMERPQAFMENKTEEIAETLGKTGGIGTVATRADIIEKLFQSFLIEKRGKDLFITSKGKQLLDLVPEDLRTPALTAEWEQKLEAIANGKLTKQAFISDMKQYAKSIVGSIKASDKTFRHDNITGSKCPECGKLMLEVNGKRGKMRVCQDRECGYKKNIAKVTNARCPKCKKKLELRGEGEGQTFACVCGHREKLSVFNERKKKNKHKQVSKREVSNYMKKQNKDEDFGNTALADALAKLKLDK
(1584) DNA topoisomerase 1 [Anoxybacillus flavithermus WK1]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGVDIQNDYEPKYITIRGKGSVIKELKTAAKKAKKVFLAADPDREGEAIAWHLAHLLDLNTESPCRVVFNEITKDAIKQSFEQPRAINMHLVHAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREKEIQSFQPEEYWTIQGTFMKGNDTFEAQFYRLGSEPFDLKTEQDVQHVLNHIQGNEFVVTAVTKKERKRNPVAPFITSSLQQEAARKLNFRTKKTMMVAQQLYEGIDLGSEGTVGLITYMRTDSTRVSESAQQEAIQYIEQTFGTSYVATEKRKEKQKANAQDAHEAIRPTSVWRHPSAIKPHVTRDQYQLYKLIWERFIASQMAPAVLDTVAIELSNGSVVFRATGSTVKFPGFMKVYVEGTDDPKDEQQRLLPDFVEGERVFSKDIEGKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRNYVTLENKRFVPTELGEIVLDLMMQFFPEILDVEFTAKMEKSLDDIEEGKVEWVRIIDEFYREFEKRLKIAEVEMEKVEIADESADVDCEVCGSPMVYKMGRFGKFIACSNFPQCRNTKAIVKDIGVKCPRCHEGNIVERKSKKKRMFYGCDRFPTCDFVSWDKPINRPCPKCGGMLVEKKGKKSVHIQCTQCEYNEQQ
(589) DNA topoisomerase [Anoxybacillus flavithermus WK1]
7
MKVIIAEKPDQGKTLASIFQTKKREGYIEILPNEMFPKGAYMTWAVGHLFELASPETYEASWKRWTLDTLPIIPDRFQYEIDRKKAKQFAIIKQLLRKPEVVEIIHAGDAGREGELIIRNIIYMSGVKKPIKRLWISSLTPKAIEQGFRQLLDEKQTRPLYEEAYARTCADWLVGINASRVYTILLKQKGMNDVFSVGRVQTPTLALIVRREKEIEQFHPKPFWEVVATFDVDGKRYEGKWWHENETRTYDRELAEKVSAFCRRKQVEVAEVVCERKTFLPPLLFNLSTLQATANKRFKYSPQKTLDILQKLYQKGYVSYPRSDSQYVTKGEAETFPHILKQLSQKEEYAPYFPLVHESILHNKRYVNEKKVTDHYAIIPTEQVPNLTKLSQDERNIYDLIVRRLIAAHSEEAIFDYTTIVTVVDGRARFISKGKKQIQAGWRDVLMSQDDDVQLLPNVQSGEKGTVYDVYVKEGKTQPPKRYTEGELITLMKTAGKFLDDEQLEKVLAKTEGLGTEATRASIITTLKQRNYIEIKNNQVYVTDKGKVLIDAIGPHLLASPEMTAKWEQRLSEIGEEKASATAFMEQVKKLAAKIVADAVQVANDWSFEGLDTASIQRKKKTTIGKHVGVCKLCGGSVIDKGSFYGCVNYTKTKCSFTISKTILGKSISQANVKKLLAEGKTNVIKGFKKGENTFNAAVIWDETEKRISFSFEK
(179) DNA topoisomerase III [Bacillus selenitireducens MLS10]
7
MQLIIAEKPDQGAKLAAPFNPQKKKNFITIPACSHFPEGAVVTWAVGHLCELVPPEHYRSEWKTWSMDTLPILPEEFRFQVIKGKGKAFQTIKSFIHDQDITGIIHAGDAEREGEAIIRMILHQARNQKPVKRLWISSLTPDAVKEGFSALLDSIDTDHLYDEALSRSFADWLVGINASRAYTLQFKKHGINDVYSTGRVQTPTLALIVKRENEIDEFVSKPFWEVHATFSHEQGSYGAVWHKDGDSRLLNSVMAERIQAFCTNRPARILDQRVKQKAIPAPSFFNLSSLQAAMNKRYTFSPKHTLEIAQKLYVKGYISYPRTDSTFITTQEERQFPGILKKLEKKEPFSAHFPLPFSSLQNRNRYVNEKKVRDHYAIIPTEQVPSFSKLSADEQKIYEVIVNSLIAAHYPPLMMSYTEIDTIVDERAEFKSKGKSVISPGWRDVIPFPKANSQEQWLPNVDKGDAVTGDSFEVKESETKPPKRYTEGELITLMKTAGKHVDDRELTGILHETEGLGTEATRANIIAVLQQRNYITITKNTVFPTDKGKLLITALGSSPLASHAITARWEQALSSIGNGKKSKDEFMASIHTFIQNLIDESLHLSAEWVFTPEDIAKLPARKSKWDAYKNRSKEPLGPCPICGAQVMDKGKFYGCEAYLSNKCSFTLSKRIMKKTLPKTAVKNMLKSKESPVISGFQSKGKSFAASMIWSESEKRFIFDFKEPRKMKPE
(998) DNA topoisomerase 1 [Bacillus selenitireducens MLS10]
1
MSDYLVIVESPAKAKTIGKYLGKKYNVKASMGHVIDLPKSQMGVDVENNYEPKYITIRGKGPILKDLKQAAKKAKRIYLAADPDREGEAIAWHLADSLKIEEGSKCRVVFNEITKDAIKESFKHPREINTNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVAVKMIIDRENEINAFVPEEYWSITAHLSKDGKQFEAKFQQLDGEKKPLSSKEDVDDILNRLEGGSFEVTGIKRRERKRNPVAPFITSSLQQEAARKLNFRAKKTMMLAQQLYEGVDLGKSGTVGLITYMRTDSTRLSDTAKGEAKEYIGIHYGEEYHQEPKAAKKNEKAQDAHEAVRPTSVMRDPKAMKPHLSRDQYRLYKLIWERMVASQMAPAVMDTMSVDLDVNGAMFRATGSKLKFAGFMKVYIEGNDEGKEEKDKLLPDLNQGDKPASEKVEPAQHFTQPPPRYTEARLVRTMEELGIGRPSTYAPTLDTIQRRGYVSLEEKRFVPTELGTIVLEMIEEFFPEILNVEFTADMETRLDSVEEGSEEWIRIIDEFYQGFEKRLKYAEEEMKEVEIKDEPAGEDCEKCGHEMVYKMGRYGKFMACSNFPNCRNTKAIVKEIGVGCPKCEKGQIVERKSKKRRIFYGCDQYPECDFISWDKPIARTCPKCSEMLVEKKSKKTVQVVCVSCDYKEDSV
(513) DNA topoisomerase 1 [Geobacillus kaustophilus HTA426]
1
MSDYLVIVESPTKAKTIERYLGKKYTVKASMGHVRDLPKSQMGVDIDHGYEPKYITIRGKGQVIKELKTAAKKAKKVFLAADPDREGEAIAWHLAHMLDLDIHSDCRVVFHEITKDAIQQSFQQPRAINMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREREIREFQPEEYWTIQATFQKEGETFAASFYSIDGQKRDLKTEADVKAVLDRLNGTAFAVKTVTKRERKRSPVPPFTTSSLQQEAARKLNFRTKKTMMIAQQLYEGIDLGSEGTVGLITYMRTDSTRVAETAQQEAAAYIEATFGAMYVNQEKRKEKKSTNAQDAHEAIRPTSAFRDPDKVKPYLTRDQFRLYKLIWERFIASQMAAAVLDTMSVELENNGVVFRASGSKVKFPGFMKVYIEGTDDQTEEQDRILPDLEEEETVESETIESKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRNYVVLENKRFVPTELGEIVVELMLEFFPEIIDVEFTAKMEKELDEIEEGKVEWIKVVDEFYREFEKRLKVAEKEMRAVEIKDEPAGIDCEVCGSPMVYKMGRFGKFIACSNFPECRHTKPIVKEIGVKCPKCREGNIVERSTKRKRVFYGCDRFPDCDFVSWDKPLARPCPKCAGLLVEKVLKKGVQVQCTACDYEERLEA
(803) DNA topoisomerase [Geobacillus kaustophilus HTA426]
7
MKVIIAEKPDQGATLASIFRTKKRQGYIEILPNDLFPDGAYMTWAIGHLFQLAPPERYRPEWKRWTLGTLPIIPERFEYEIEKAKAKQFKVVKELLRKPEVTEIIHAGDAGREGELIVRNLIRLSGVNKPMKRLWLSSLTPKAIEEGFRRLLDERTTRPLYEEAYARACADWLVGMNASRVYSLLLKERGMNDVFSVGRVQTPTLALIVRREREIEQFRPEPFWEVVASFVIGDKRYEGKWTDKNGQTRLGDEEMAKKIAAFCQGKRAEVADVHTERKTYQPPLLFNLSTLQATANKLYRFSPKKTLDVLQSLYQKGIVSYPRSDSMHVTKGEAETFPAILQKLSSFPAYASYFPLPQPSILQNKRYVNEKKVTDHYAIIPTEQVVDPEKLSADERKVYDLVVRRLIAAHHQAAVIDYTTVTTLVDGRARFVSKGRQVVEEGWRAVIRPHEEEKDAALPLLERGEAGEAAAVKVKEGKTEPPKRYTEGELITLMKTAGKFLDDEELEKVLAKTEGLGTEATRAAIITMLKERKYIEVKNNLVYATDKAKVLIEALGGTILASPEMTAKWEQRLSEIGEGSASPAAFMEQVKKLAQKVVADAIAAAPNWNFRGVDTASIQRTRKKKTMGEKLGPCPLCGGTVVDKGTLYGCDQYAKTKCPFTISKRILGKSISAANVKKLLSQGKTNVIKGFKKGEKTFDAILVWDENEKKLSFQFPKR
(1640) DNA topoisomerase [Geobacillus kaustophilus HTA426]
7
MKSLVLAEKPSVARDIARVLGCKQAHKHYFEGKQHIVTWALGHLVELKMPEDYDRKYETWRLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRPDVKDVIIATDAGREGELVARWILEMIGWTKPIWRLWISSQTDRAIRDGFRQLKPGVQFERLYQSAVCRAEADWLIGLNVSRALTTKYNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIRAKIGSITAVWERHGGHRLFDQDEANRLMTRLKGQPARVTSIKRKRKSEPAPLPYDLTELQRDANKRFGFSAKKTLSVLQRLYEQHKLVTYPRTDSRYLPSDMEATMTERLLAMKSGYEDVIAPLLAKGKAKAAKRVFNDDKVTDHHAIVPTDERLNLSRLSTDERKLYDLIARRFLALFYPPHESETTTAVFDIGGETFVAKETAVVNAGFQAVLSKEDNKAQPTLLHLAEGQTLPSVQLELEQSFTEPPARYSEADLLAQMEKYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEELKSPELTARWERELEAIARGKGNPQQFLANIRRQTQQLVAEIKQSEQVYKAPNLTNLTCPECGALLKERKTKDGRMLVCSNLQCRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGLYFQCRPCNIVEKADETKRIAAKGSERALLKKYSASNESFGVSLGELFKQALSQKEE
(1750) DNA topoisomerase [Bacillus anthracis]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDESDTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYDGKWEKDNESRLQDPDMANKIAAFCQGKPAVVKEMKTERKEFQPPLLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPVESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSRLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTIVTLVDERAEFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEEGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGSCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKTISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(351) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(837) DNA topoisomerase 1 [Bacillus anthracis]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(1751) DNA topoisomerase [Bacillus anthracis]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDESDTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYDGKWEKDNESRLQDPDMANKIAAFCQGKPAVVKEMKTERKEFQPPLLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPVESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSRLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTIVTLVDERAEFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEEGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGSCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKTISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(352) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(838) DNA topoisomerase 1 [Bacillus anthracis]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(836) DNA topoisomerase 1 [Bacillus anthracis]
1
MSDYLVIVESPSKAKTIEKYLGKKYKVVASMGHVRDLPKSQMGIEVKNNFTPKYITIRGKGPVLKDLKSAAKKAKKVYLAADPDREGEAIAWHLANTLNVDVESDCRVVFNEITKDAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSVAVRLIIEREREIQSFEPEEFWTIKTEFVKGKDTFEASFYGVDGEKVQLTNETQVNEIIEQLKDNAFSVENVTRKERKRNPALPFTTSSLQQEAARKLNMRAKKTMMLAQQLYEGIDLGKQGTVGLITYMRTDSTRISETAQTEARTYITEAYGTEYIGAEKKKETKKSNAQDAHEAIRPTSVMRKPEELKSFLSRDQLRLYKLIWERFVASQMASAIMDTVTARLINNNVQFRASGSVVKFPGFMKVYVESKDDGAEEKDKMLPPLEVGETVFSKDLEPKQHFTQPPPRYTEARLVRTLEELGIGRPSTYVPTLETIQKRGYVGLDNKRFVPTELGEIVIELILEFFPEIINIEFTANMEQSLDEVEEGNANWVKIVDDFYVGFEPRLEKAEKEMREVEIKDEPAGEDCELCNHPMVFKMGKYGKFMACSNFPDCRNTKPIVKEIGVTCPKCDKGQIIERRSNKKKRLFYGCGTYPECDFVSWDKPIGRKCPKCEGMLVEKKLKKGVQVQCISCDYEEEQQM
(350) DNA topoisomerase 3 [Bacillus anthracis]
2
MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
(1749) DNA topoisomerase [Bacillus anthracis]
7
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDESDTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYDGKWEKDNESRLQDPDMANKIAAFCQGKPAVVKEMKTERKEFQPPLLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPVESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSRLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTIVTLVDERAEFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEEGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGSCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKTISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
(102) DNA topoisomerase 1 [Bacillus megaterium WSH-002]
1
MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGIDIEQDYNPKYITIRGKGPVLKELKTAAKKAKKIYLAADPDREGEAIAWHLAHSLDVDIASDCRVVFNEITKEAIKESFKHPRAINMDLVDAQQARRILDRLVGYNISPLLWKKVKKGLSAGRVQSIAVRLIIDREKEIAKFIPEEYWTVKATFQKGNDQFEGQLIEYQGKKVELSNENDVTNIVKQLDGNEFSISKVTKRERKRNAAPSFTTSSLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISETAQTEARDYITNAYGNQFVATEKRKEKKNSNAQDAHEAIRPTSALRKPGEVKEFLSRDQYRLYKLVWERFVASQMAPAIMDTMAVDLKNGDVTFRANGSKVKFPGFMKVYVEGNDDQVEEKENLLPDLEEGEVAYSKDIDEKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRGYVALDNKRFVPTELGEIVLELVLEFFPEILDVEFTAKMENDLDEVEDGNVQWVRVIDEFYSDFEKRLEHAEKEMREVEIKDEPAGEDCEECGSPMVYKMGRYGKFMACSNFPDCRNTKPIVKEIGVKCPKCEEGNIVERKSKKKRTFYGCDRFPGCDFVSWDKPIARKCPKCENLLVEKKQKKGTQVVCTSCDYKEEAQQ
(1314) DNA topoisomerase [Bacillus megaterium WSH-002]
7
MKLIIAEKPDQGSTLASQFKPKRHDGYLEIPPNEVFTDGAYVTWAVGHLCQLVSPEDYKPEWKKWSIDTLPMIPDRFQYEVTRSKAKQFQVVKKLLKKPTVTEIIHAGDAGREGELIVRNIIQLSGVHKPMKRLWISSLTPKAIYDGFQQLKDESDTRNLYYEAYTRACADWVVGMNASRVYSILLKKHGMSDVFSAGRVQTPTLALIVKREKEIDNFKSEPFWEVLAKFDIEGKKYEGKWHQDGESRLKEKEMAYKIAQFCEGKDAEVHELVTERKEFQPPLLFNLSSFQATANKAFKFSPKKTLDVLQGLYQKGIVSYPRSDSNYVTEGEAETFPEILEKLSAFSEYEHLFPLPYSSILGNKRYVNAKKVSDHYAIIPTEQVKDPSKLSGDEQKIYDLVVRRLIAAHYEKAIFDYTTITTLVEKRAAFISKGKQQIQEGWRKVIFQNEKDDDVILPNVQEGEEGKVIKVDVKEGKTQPPKRYTEGQLITLMKTAGKHLDNDELEKILAKSEGLGTEATRAGIITMLKDRKYIDVKKNQVFATDKGKVLIDAIGDKILASPEMTAKWEQRLAEIGEGAASAAAFMEQTKKLSAKIIEDAVEAESKWNFSGYDTESIQRKGKGKGKSFSSKSFGSCKLCDGKVVDKGSFYGCSNYAKTKCTFTVSKKILGKTVTQANLKKLLSEGQTDLIEGFKKGDKTFNAKLEWKENKVQFLFEK
(216) DNA topoisomerase [Bacillus megaterium WSH-002]
2
MKSLVLAEKPSVARDLARVLGSTQTKKGYIEGPKYVVTWALGHLVELQTPEDYDNQYKTWRLEDLPIMPEKMKLKVIRKVSSQFRTVSDLAKRKDIGELIIATDAGREGELVARWIMEKVRWNKPFKRLWISSQTDKAIRDGFKQLKPGKEFNRLYDSAVCRSEADWLIGLNVTRALTTKYEEPLSAGRVQTPTLAMIIEREQVINTFKPSEYWTLTAQFSSFEAAWQKGNEKRIFDEKRAKELHSKLSGEAVVNTIKRKMHKEAQPLPYDLNELQRDANKRFNFSAKKTLNVLQKLYEQHKLVTYPRTDSRYLTTDMVSTMKERLESISAVYKEEVRPILRNAQLPKRVVNNEKVSDHHAIIVTDQPVFLQDLSADERKLYDLIAKRFISLFYPAYEYEVVKAELEVNGEQLVASGKQVVNAGFKKVSGGESEATVKLPDMKEGSKLSIQDVTMKSAFTEPPQRYTEADLLGQMEKHNLGTPATRADIIEKLLQNESIDRQNNRLHATKKGKQLIDLVADELKSPELTAKWERELEAIAKGKGNAKEFLTNIREQTEKLVKQVKTSNQTYKPHNLTGSKCPECGTFLKEKKTKQGRVLVCSSLECSYRRAKDPKLSNRRCPQCHKRMEIHSGKAGTYFQCRSCQVVEKAEDKKKKISKREERKLLNKYNDDGAFGSSLGDALKQALQDKKD
(111) DNA topoisomerase III [Lysinibacillus sphaericus C3-41]
7
MKIVIAAKPDQAAKLAAPWSFTIKTGYFEVKANSYFPNGAIITWATGHLCELKTPEEYDSTWKKWKLETLPIIPDRFEYKVSKSKYKQFTIIKNLVKRADIQEIIIGGDAGREGELIIRTILRVCGVNKPMKRLWISSLTENSVKNGFSNLLPEAQTKDIYYEALSRSCADWLIGINTSRLYTVLLKKNGVKDVFSIGRVQTPTLALIVHREHEIANFKSEPFWEVEAVFHFAGKMLKAKWHKNNMSRVLEEKQAIAIANFCLHKNVDITKIIKETKEYAPPLLFNLSGLQATANKAYKFSPQKTLDILQKLYVKGLVSYPRSDSQFLTSEEAKTLPTILNNLSKMDKYKNLLPPPINSIMHNKRYVNEKKVTDHHAIIVTEQMPNLSKLSMEEEKIYDLVARQVIAAHYNHAIFAYTTIHSLVDKRAEFISKGKEQIEEGWRKVIYPTKDSSSQEEEEMLPLLHENELGTVAQASVKQGATQPPNRYSEGHLITLMKTAGKHLDDAELEKVLSKTEGLGTEATRAGIIGTLKDRQYIEIKKNQVFATSKGMLLIEALGENSLLTSPSMTAKWEQRLAEIGEGHASPQAFMEQVKKLTYKLITDAHEREKAWTFDQKEVEKISANNPYQKKYKKEKTVVGKCILCNGSIIDHGTFYGCSNYKAANCKFSVSKKILSKTISQTNVRKLLATGETDMIKGFKKGQKTFNAHLIWDKQEHRVHFKFPQ
(1855) DNA topoisomerase 3 [Lysinibacillus sphaericus C3-41]
2
MLYMAKSLVLAEKPSVARDIANVLKCHKKGNGYIEGDKYIVTWALGHLVTLADPESYDEKYKKWNLEDLPMLPERLKLTTIKQTSKQYNAVKSQLTRNDVNEIIIATDAGREGELVARWIIDRAKVNKPIKRLWISSVTDKAIKDGFANLKPGKNYDNLYQAAVARSEADWYLGLNSSRALSTKFNAQLNTGRVQTPVVAMVAAREDEIKNFKAQTFYGIEAQTKELKLTWQDASGNSRSFSKEKVDAIVNSLDKQDAKVIEIERKPKKSFSPGLYDLTELQRDANKIFGYSAKETLNIMQKLYESHKVLTYPRTDSRYLSSDIVSTLPERLKACGIGEYRTLANKVLSKPIKANKSFVDDSKVSDHHAIIPTEEYVNFANFTDKERKIYDLVVKRFLAVLFPAYEYEQLTVQGQIGNEKFIARGKTVISAGWKEVYSNRFDDEESSEDVKEQLLPRLEKGQVLKVNLITQTSGQTKPPARFTEATLLSAMENPTKYMNTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPNELKSPETTAEWEQKLELIAKGKLKKETFINEMKQHTKEIVADIKNSDKRFKHDNISTKTCPDCGKPMLEVNGKKGKILVCQDRECGHRKNVSRVTNARCPQCKKKLELRGEGDGQIFVCKCGYREKLSAFEARRKKEGGGKVDKRSVQKYMKQQEKEAEPLNNAFADLLKGFNVDK
(1837) DNA topoisomerase 1 [Bacillus pumilus SAFR-032]
1
MADYLVIVESPAKAKTIERYLGKKYKVKASMGHIRDLPKSQLGVDTEHDFEPRYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDLSSDCRVVFNEITKDAIKDSFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKKGLSAGRVQSVALRLIIDRENEINEFKPEEYWTIDGTFLKGKESFEASFFGVNGKKHPLKTKEDVKEILSKLKGSKFSVEKVTKKERKRNPAVPFTTSTLQQEAARKLNFRAKKTMMIAQQLYEGIDLGKEGTVGLITYMRTDSTRISNTAIEEVSAFIDQTYGKNFLNTTKRTVKKNENAQDAHEAIRPTSTLRKPADVKHVLSRDQLRLYKLIWERFVASQMAPAVLDTMSVDLDNNGLTFRANGSKVKFPGFMKVYVEGKDDQLEEKDKMLPDLKEGDTVLSKDIEPEQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRGYVALDNKRFIPTELGEIVLNLIIEFFPEIINVEFTAKMEKELDSVEEGTIEWVRIIDSFYQDFAKRVEKAEAEMQEVEIEPEYAGVDCEECGHPMVYKMGRYGKFMACSNFPDCRNTKPIVKDIGVKCPTCHEGNIVERKSKKRRIFYGCDRFPECEFVSWDKPIERKCPKCENMLVEKKLKKGMQVQCVNCDYKEEQQK
(1582) DNA topoisomerase 3 [Bacillus pumilus SAFR-032]
2
MSKTVVLAEKPSVGRDLARVLKCHKKGNGFLEGDQYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVMKKTGKQFQAVKAQLARKDVKDIVIATDAGREGELVARWILEKAHVKKPLKRLWISSVTDKAIQEGFKRLKDGKEYDNLYRSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTIAMIFKREEDIQQFQPKPFYGLTAQVDGLTLTWQDAKTKQNRTFQENVIKERLAACKGKPAVVDALKKTAKKAFAPGLYDLTELQRDAHKRYGFSAKETLSTLQRLYEQHKLVTYPRTDSRFISADIVPTLKDRLKGMNVRPYAQHVNRILQSGVKAHKGFVNDAKVSDHHAIIPTEEELYPGVLSDKERKLYDLIAKRFLAVLMNPFEYEETTVITKIGSETFTAKGKTVQAAGWKAVYDDSYEEEESAEADQHLPLLSEGQSLDVRQLKETRGETKPPARFNEATLLSAMENPAAFMQNEEKDLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKGKDIFITSKGKQLLSLVPEDLKSPALTAEWEQKLSKIAKGQLKASQFMSEMKSYAKQAVSEIKQTNQTFKHDNVTGTHCPDCGKLMLKVNGKHGTMLVCQDRECGHRKNVAKKTNARCPNCHKKLELRGEGDGKIFACVCGHREKLSVFEKRKSQSNQKKASKHDVSKYMKKQKKVEEPINNALAEQLKKLKLDQ
(303) DNA topoisomerase [Geobacillus thermodenitrificans NG80-2]
7
MKSLVLAEKPSVARDIARVLGCKKTHKSYLEGPRYIVTWALGHLVELKMPEDYDRKYETWRLEDLPIIPKKMGLKVIRQTSHQFRAIERLAKRRDVKDCIIATDAGREGELVARWILQKIDWKKPIWRLWISSQTDQAIRDGFRQLKPGTQFDRLYESAICRAEADWLIGLNVTRALTTKYNDPLSAGRVQTPTLAMIIEREREIQSFVPVPYWTIHARIGSVTAVWERHGGKRLFDKDEANELMTRLKGQPARVTSVKRKRKSEPVPLPYDLTELQREANKRFGFSAKKTLSVLQRLYEQHKLVTYPRTDSRYLPSDMKATMTDRLLAMKPGYEDVISSLLTKKNVKAANRVFQDDKVTDHHAIIPTDERLDLAKLSVDERKLYDMIARRFLALFYPPYEYETATVVFEIGDETFVARETAVVNAGFKAVLGKEETEAKPTLLHLSEGQTLASVQLEMEQSFTEPPSRYSEADLLAQMERYGLGTPATRADIIERLVETEVVERKDGRFYPTKKGKQLIELVNEELKSPELTARWERELEAIARGKGNPKQFLANIRRQTEQLVTEIKQSEQTYKAPNLTNLTCPECGSLLKERKTKDGRMLVCSNLECRYRRRRDPKLSNRRCPQCHRRMEMHEGKAGLYFQCRPCNIVEKAEETKRTSAKGTERALLKKYSPSNESFGTSLGELLKQALEKKE
(576) DNA topoisomerase [Geobacillus thermodenitrificans NG80-2]
7
MKVIIAEKPDQGATLASIFRTKKRQGYIEILPNDLFPDGAYMTWAIGHLCQLAPPERYRSEWKRWTLKALPIIPERFEYEVEKAKAKQFKVVKELLRKPEVKEIIHAGDAGREGELIVRNIIRLSGVNKPMKRLWLSSLTPKAIEEGFRRLLDERTTRPLYEEAYARACADWLVGMNASRAYSLLLKERGMNDVFSVGRVQTPTLALIVRREREIEQFRPEPFWEVVASFVIGDKQYEGKWIDENGQTRLKDEAMAKNIAAFCRGKQAVVADVRTDRKTFQPPLLFNLSTLQATANKLYRFSPKKTLDVLQSLYQKGIVSYPRSDSMHVTRGEAETFPAILQKLSAFSAYASYFPLPQPSILHNKRYVNEKKVTDHYAIIPTEQVVDPEKLSADERKVYDLIVRRLIAAHHQAAVIDYTTVATLVDGRARFITKGRQVIEEGWRAVIRPHEEEKETVLPLLCQGEAGEVADIQVKEGKTEPPKRYTEGQLITLMKTAGKFLDDEALEKVLAKTEGLGTEATRAAIITMLKERKYIEVKNNLVYATDKAKVLIEALGGTILASPEMTAKWEQRLSEIGEGAASSAAFMEQAKKLAQKVVADAIAAAPSWNFSGLDTASIQRTKTKKTVGEPLGRCPLCGGTVVDKGTLYGCDQYVKTSCSFTVSKRILGKSISAANMKKLLAKGKTNVIKGFKKGGKTFDAVLVWDENDKKLSFQFPKR
(74) DNA topoisomerase 1 [Geobacillus thermodenitrificans NG80-2]
1
MSDYLVIVESPTKAKTIERYLGKKYTVKASMGHVRDLPKSQMGVDINDGYTPKYITIRGKGQVIKELKTAAKKAKKVFLAADPDREGEAIAWHLANMLDLDIHSDCRVVFHEITKDAIKQSFQQPRSINMNLVDAQQARRVLDRLVGYNISPLLWKKVKKGLSAGRVQSVALRLIIDREKEIRQFQPEEYWTIQAKFQKGKEAFAASFYGVDGEKLELKTEADVKEVLARLNGRAFTVKTVTKRERRRSPVPPFTTSSLQQEAARKLNFRTKKTMMVAQQLYEGIDLGGEGTVGLITYMRTDSTRIAETAQQEAAAYIEATFGAQYVHQEKRKEKKSTNAQDAHEAIRPTSAFRDPDKVKPYLTRDQFRLYKLIWERFIASQMAAAVLDTMSVELENNGVLFRASGSKVKFPGFMKVYIEGTDDQTEEQDRLLPDLEEGEAVESEMIEPKQHFTQPPPRYTEARLVKTLEELGIGRPSTYAPTLDTIQKRNYVVLENKRFVPTELGEIVVELILEFFPEIIDVEFTAKMEKELDEIEEGKVEWIKVVDEFYREFEKRLKVAEKEMREVEIKDEPAGIDCDVCGSPMVYKMGRFGKFIACSNFPECRHTKPIVKEIGVKCPKCHEGNIVERNSKRKRVFYGCDRFPECDFVSWDKPLARPCPKCGGLLVEKKLKKGVQVQCTACDYEEQPEA
Family distribution
Taxonomy tree
Bacillaceae