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Taxon : Lactobacillales
Informations
Name
Lactobacillales
Rank
order
# topoisomerases
87
Lineage and sub-taxa
Lineage
Bacteria
>
Firmicutes
>
Bacilli
>
Lactobacillales
Sub-taxa
Topoisomerases
Select all
Name
Family
Sequence
(937) Putative DNA topoisomerase [Lactobacillus brevis]
3
MSIVVLTEKSSQIDPYAKALGTPKKKQGSVWVHSALLNADVQFVAASGHLFKLDGPEDYNDAWRDRSNYEQLPMVPQKFKARIKDARARASFNRIKQAITAADEVILATDPDQQGEVIGREILQRIPGGMEKCQRRLLNSSLTAKGALRSFENLVPMAKQEHLGAAGFLQNRLNWLIGMNLSRVGGIQLKKRGYYFPVAAGTVKTPTLALVVANDQEIKHFKEAPYWQIELTDQANQQRFKAQPSRHFSIEDEAKQALAQVTDTLTIKSVDQVEQHRLPPKLFNLTALQGYAAKKWGYSGTEVLETMEHLYKDLAITSYPRTESTVIEDAEFDYLKANFNDYAATLNLKMAMQVPDARPEFVKTTTDGHPALIPTDKVADLSQLTERERRCYGAVVKRTLLMFAGDCVLDKTVVKGTLGTEQIYEATGQQFKDLGWTEFDVVKTENRELPSYQQGQQVKIETSLVEGKTKVPQRITEGMLFSKLFPKYNLGTPATRAGIVSELIEKNHYIEVKGKRRELYPTSEGINMVAFWQGTLLTDLKLAKSWQDIFDKVIQGNMQPDRYQEQMVEALTDIVADYRTKKPDLPIAPKPHTSYEFKPLTPAVKCPKCHRGELGLLVATNAKNNQFYACSQKKCHFSLPNKYSGIALTSELVRQLATKKQTDWLPEVKSSQGKVYRNQVAFILAEKLKLQWTFKQTAKKTERTD
(1078) DNA topoisomerase 1 [Streptococcus gordonii str. Challis]
1
MYKLVTKTSKKSTTKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSTMSIDFENNYEPQYINIRGKGPLINDLRKEAKKAKQVFLASDPDREGEAISWHLAHILNLDEKEKNRVVFNEITKDAVKNAFKEPRQINMDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEINAFKPEEYWTIDSTFKKGSRQFQASFYGINGRKMKLTNNDEVKEVLSLLKGDDFKVESVERKERRRNAPLPYTTSSMQQDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAANYITDRFGAKYSKHGSKIKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMNVKIEQNGVQFTANGSQVKFDGYLAIYNDSDKNKMLPDMEKGDTVKRVNTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVKLVSKRFEPTELGEIVNSLIVEFFPGIVNVKFTAEMEAKLDDVEVGKEQWQKVIDEFYRPFEKEVAKAESEMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVTCPQCQKGHVIERKTKRNRIFYGCNRYPDCDFTSWDKPVGRNCPKCDHYLVEKKVRGGGKQVVCSNGDYEEEKVK
(815) DNA topoisomerase 1 [Lactobacillus johnsonii NCC 533]
1
MPTKRKNKKNLVIVESPHKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGVDVEHDYEPKYISIRGKGDTIKELKSEAKKAKYVYLASDPDREGEAIAWHVAHALNLDPKEHNRVAFNEITKDAVKNAFKNPRTIDMDIVDAQQARRVLDRLVGYSISPILWQKVKKGLSAGRVQSIALKLVIDRENEIKNFKPEEYWTIDADFEKGSEKFKGAFYGIKGKKQELPNNEAVQDVLKRIDKRKNFEITKVVKKERRRQPAAPFTTSTMQQEANKRLGYRTRRTMRIAQSLYEGVNLGKGSVGLITYMRTDSKRIANVAKHEASKFIHEEYGENYAAVKPQHFKNDADAQDAHEAIRPTSAFRTPASVKEYLTTEEYRLYTLIWSRFIASQMTPAVYDTVRADIEQNDVTFRTTGSKLKFAGFTKVYDNQKEKSNELPELNEGDKVKLKKTDDRQHFTQPPARYTEASLVRTLEENGVGRPSTYAPTIDTIQKRYYVKLEGRSIVPTELGEIVDKLIEEFFPDIVNVDFTAQLENDLDGVEVGKKNWIKVVDEYYKPFSKELDKADQQIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVTCPKCGKGEVIEKKSKRNRKFYGCSRYPDCDFVSWDQPIGRNCPNDGHFLVQKKNKKGLVILCPNGDYREEPEEN
(809) DNA topoisomerase 1 [Lactobacillus acidophilus NCFM]
1
MPTKAKSKSKTKKRKKILVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHVAHALDLDENAKNRVTFNEVTKDAVKESFKHPRSIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWSIDAEFSKGKDTFKSSFYGIDGKKKELPNNDAVKEVLAKIDKRKNFEVENVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKEGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVMFRTTGSKMKFPGFTKVYDNQQEKSVDLPDLQEGDKVKMTKSDNKQHFTLPPARYTEASLVRALEENGVGRPSTYAPTIDTIQRRYYVKLDGRSIVPTELGEIVDTLIEEFFPDIANVDYTAHLENELDEVEDGKKEWVHVVDEYYQPFKKELTKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVVCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVVLCPNGDYKEEPQEGETDK
(379) DNA topoisomerase 1 [Weissella koreensis KACC 15510]
1
MPTTTKDKPKAKKRTTTKRKKNLVIVESPSKAKTIEKYLGSGYKVVASIGHIRDLPKSQMGVDTENDYNPKYINIRGKGDVIKNLKKEAKAAKHVYLASDPDREGESIAWHLAHILDLDTSSEENRVVFNEITKDAVKDAFKRPRQLDMNLVNAQQARRILDRLVGYSISPLLWKKIKKGLSAGRVQSGALGLIIDRENDIQAFQPEEYWELPAEFKKSNKKFKAGFYGLDGQKVKRIPDNEMVQSILKRIDQNQEFDISEVVKSEGKNNPSPAFTTSTLQQAANTQLSFQTRRTMSTAQQLYEGINLGGKEGSVGLITYMRTDSTRISSIAKNDASKFIHEEYGDEYAATKPVQGKLQEGAQDAHEAVRPTSVFRTPKSIKDKLTNDQFKLYQLIWSRFVASQMTAEVIDRVRVTLTQNGVMFRANGATTKFAGYTKAYPAAKAKDNVLPEMVEGGNVKLDKINPEQKFTQPKPRYTEAALVKALEEAGVGRPSTYAATIETLKSRAYVKMDAKKFIPTEIGKMVQDAVRDYFPDVADLKFTAQIEGELDNVETGNEDWVKVVDEFYKPFKGELDIAESEMEKIVVKDKLAGENCEICGAPMLERLGRYGKFFACSRFPDCRNTKTIVKEIGLVCPKCHQGQIIERKTKRGRTFYGCSRYPDCEFISWDKPTEKTLADGTTPKDGEDNKKSKTTKSKKPATKKATKKKAAKK
(5) DNA topoisomerase [Weissella koreensis KACC 15510]
7
MRTIILAEKPTQAVAYSKAFKSSKKREGYIEVSNEYFDGETYITYGFGHLVELYLPEQYDEKYKNWSINNLPIIPDQFKFKTGKGKAEQFKIVKNLLSEADQIIIATDADREGENIAWSIINQSGINPQEKIMKRLWINSLESSAIRDGLTNLHEAKQHYSAYIEAQTREFSDWLVGMNASPLYSLSLRKQGIRGVFSIGRVQTPTLYMIYKRQVEIDNFKPKPYIELLAHVKTGKSEFEAKLDPFIRFDNQDKVKVFLSDNELVLVNKSQSKENNNNFGIINNIIKDKKKQPSPKLFSLSTLQSRANKAFKASAQNTLDAVQSLYEKKFLTYPRTDTQFISDEEFSYLLDNINQYCEFANVTANIAHKEPRKRYVNSKKVQEHHAIIPTRTIPTKNQFMKLTSLEKSIYELVLRTTIAMFLDDLNYDEQVIIVKSGQAQFKAMGRVITTPGWKLLFKTNSKKSSANGEVSLPRVDIGQKVDFDLLDEHKVTVAPSAYTEGTLITAMKNAGRDLADAQKEILKETEGIGTEATRAGIIERLKAKSYIELKDNSLAVTMSGIILCQAVELQPLLNSPELTAQWEMALHEIGQNNRTQASFLKQIEKFILKLINEVPDQIETNQKLTDQINSQKDTNADQYKEHMGICPVCKAGHMIDRGKFYGCSNYNSKEACNFSLPSKWAGKILPKTAIKDLIKKGHTKEISGFKSKAGKSFSAILELVDGKLKFVFDK
(1561) DNA topoisomerase 1 [Streptococcus mutans UA159]
1
MTSKTTTTVKKTSKKRATPKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKNAKQIFLASDPDREGEAISWHLAHILDLDLKGKNRVVFNEITKDAVKNAFVEPRQIDMDLVDAQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWSIDGFFKKGNKKFQANFYGLDNKKTKLKSNDDVKKVLTRIKNDDFLVDKVEKKERKRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGIRLGSNGQQGLITYMRTDSTRISPVAQNDAANYITEHFGAEYSKHGNHVRNASGAQDAHEAIRPSNVNHTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLTQNGVLFIANGSQIKFKGYMAVYNDSDKTKVLPEMIKGETVKKISANPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLETIQKRYYVRLVSKRFEPTELGEIVNSLIIEFFPDIVDVKFTAEMESKLDEVEIGKEEWQKVIDQFYKPFEKEVIKAEEQMEKIQIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPDCHNTKAITKEIGVICPICQKGQVIERKTKRNRIFYGCDRYPDCDFTSWNKPIGRDCPKSGDFLVEKKIRGGGKQVVCSNEECDYKEKAVK
(760) DNA topoisomerase 1 [Streptococcus suis ST1]
1
MATKTVSKKKTTTKKNLVIVESPAKAKTIEKYLGKNYKVVASVGHIRDLKKSSMSIDFDNNYAPEYINIRGKGPLINSLKKEAKNAKQVFLASDPDREGEAISWHLAHILGLDANDKNRVVFNEITKDAVKNAFQEPRAINLDLVDAQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEISNFKPEEYWTIDATFKKGSKKFQASFYGIDGKKTKIENNEQVKEILARLDGDDFLVEQVERKERKRNAPLPYTTSTMQMDAANKINFRTRKTMMVAQQLYEGVSLGTGGTQGLITYMRTDSTRISPVAQAQAADFITERFGATYSKHGNKVKNASGAQDAHEAIRPSNVNLTPESIAKYLDKDQLRLYTLIWNRFVASQMAAAVFDTMSVRLGQNGIVFAANGSQVKFDGYMAVYNDADKNKMLPDMEQGDTVVRASTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVKLAAKRFEPTELGEIVNKLIVEFFPDIVNVKFTADMEQKLDDVEIGKEQWQKVIDGFYQPFKVELSKAEEQMEKIQIKDEPAGFDCDVCGHEMVIKLGRFGKFYACSNFPDCRNTKQITKEIGVTCPVCQKGQVIERKSKRNRLFYGCDRYPECEFTSWDKPVGRSCPKCDHYLVEKKVRGGGKQVVCPNGDYEEDKIK
(1201) DNA topoisomerase 1 [Streptococcus thermophilus JIM 8232]
1
MATATTTKTKAKKKTKAKKATKKRATPKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLIKELKKEAKKAKKVFLASDPDREGEAISWHLSHMLGLEPEDKNRVVFNEITKDAVKNAFAEPRAIDMDLVDAQQARRVLDRIVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWTIDGAFKKGAKKFQASFYGLDGKKLKLNNNDDVKDVLSRIISDDFNVDKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGINLGSGAQGLITYMRTDSTRISPVAQNQAAEFITERFGSKYSKHGSKVKNSSAAQDAHEAIRPSNVFQTPESIAKYLDKDQLKLYTLIWNRFVASQMAAAVFDTMKVTLSQNGVIFTANGSQIKFDGYMAVYNDSDKNKMLPEMAEGDTIKKVVTTPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLDVIQRRYYVKLVAKRFEPTELGEIVNSLIVEFFPDIVDVKFTAEMEAKLDKVEIGKEQWQKVIDEFFKPFQKELEKAEEGIEKIQIKDEPAGFDCDLCGHPMVIKLGRYGKFYACSNFPDCHNTKAITKEIGVTCPTCGQGQVIERKTKRNRVFYGCDRYPDCEFTSWDIPIGRNCPKSGDYLVEKKVRGGGKQVICSKEECDYKESVIK
(1013) DNA topoisomerase 1 [Streptococcus sanguinis SK36]
1
MSKLVTKTKKKSTTKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSTMSIDFENNYEPQYINIRGKGPLINDLKKEAKKAKQVFLASDPDREGEAISWHLAHILNLDEKEKNRVVFNEITKDAVKNAFKDPRQIDMDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEINAFKPEEYWTIDGTFKKGTRQFQASFYGMNGKKMKLTNNEYVKEVLSHLKGDDFTVDSVEKKERRRNAPLPYTTSSMQQDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDKFGAKYSKHGSKAKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMNVKLGQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMEKGDTVKRVNTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVKLVSKRFEPTELGEIVNSLIVEFFPGIVNVKFTAEMEAKLDDVEVGKEQWQKVIDEFYRPFEKEVAKAETEMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVTCPQCQKGQVIERKTKRNRIFYGCDRYPDCDFTSWDKPVGRNCPKCDHYLIEKKVRGGGKQVVCSNGDYEEEKVK
(545) DNA topoisomerase 1 [Lactobacillus gasseri ATCC 33323]
1
MPTKRKNKKNLVIVESPHKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGVDVEHDYEPKYISIRGKGDTIKELKSEAKKAKYVYLASDPDREGEAIAWHVAHALNLDPKEHNRVAFNEITKDAVKNAFKNPRTIDMDIVDAQQARRVLDRLVGYSISPILWQKVKKGLSAGRVQSIALKLVIDRENEIKNFKPEEYWTIDADFEKGKEKFKGAFYGIKGKKQDLPNNEAVQDILKQIDKRKNFEVTKVVKKERRRQPAAPFTTSTMQQEANKRLGYRTRRTMRIAQSLYEGVNLGKGSVGLITYMRTDSKRIANVAKHEASKFIHEEYGANYAAIKPQHFKNDADAQDAHEAIRPTSAFRTPASVKEYLTTEEYRLYTLIWSRFIASQMTPAVYDTVRADIEQNDVTFRTTGSKLKFAGFTKVYDNQKEKNNELPELNEGDKVKLKKTDDRQHFTQPPARYTEASLVRALEENGVGRPSTYAPTIDTIQKRYYVKLEGRSIVPTELGEIVDKLIEEFFPDIVNVDFTAQLEDDLDGVEVGKKNWIKVVDEYYKPFSKELDKADQQIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKVGVTCPKCGKGEVIEKKSKRNRKFYGCSRYPDCDFVSWDQPIGRNCPNDGHFLVQKKNKKGLVILCPNGDYREEPEEN
(1488) DNA topoisomerase [Streptococcus infantarius subsp. infantarius CJ18]
3
MKYLLLAEKPDQAKKYANALGNPKKDKGVWRVQSSVLNAEVIVAPAVGHLVERINPYTNFENWEMANLPALPDGFAYEPKKDTAKRFKAIKQSVKEVDAIIIGTDPDREGEAIAYRILELIPGALRKIKYRLWANSLTKKGLEQAFSKLKNPKDSINYFHEADARGDADWLVGFNLSPFVTIKMKEEGYLDKKEHSMSVGRVQTPIVSLVVRNDEAIENFKPSPYWQLKLIDPEAKVTFGNDIKYQSKAEAEQMLQQLANIAVVKTVTSEEKVQEAPELYNLTNFQSEMSKLYHFDATKTKELVQSLYQKGYLSYPRTDSTLITTNEFAYLVEHIEDYQKAINKHLETPNRSPRKNYVNDKKVLEHYAIIPTETIPDLSELSNDEKLIYQKVVFRTLLMFTPDYRYQSTSVILDNQGLEFKATGAVTKDKGWRNYLAVKKEDKELPDYQEGQTITIECKLLEEMTKPPTRITEQILLKKLLPKYNLGTSATRDGMIDLIQDKGYVTKNKKTGQFFPTERGKLLIHYLDQLEIAYTNPETTGKWEEVLAQIGQGKIQKEAFVNKIKWAITKQIEKGKQL
(263) DNA topoisomerase 1 [Streptococcus infantarius subsp. infantarius CJ18]
1
MATTTTKAQTAVKKTSKKTTKKKTAAKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLINDLKKEAKKSKKVYLASDPDREGEAISWHLAHILGLDENEKNRVVFNEITKDAVKNAFVEPRQIDMDLVDAQQARRVLDRIVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIRNFKPEEYWTIDGFFKKGTKKFQAAFYGIDGKKLKLSTNEEVQEVLARLTSDEFNVAKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGKSGTQGLITYMRTDSTRISPVAQNDAAGFITERFGENYSKHGNRVKNASGAQDAHEAIRPSNVNLTPESIAKHLDKDQLKLYTLIWNRFVASQMTAAVFDTMKVNLEQNGVRFTANGSKVKFDGYLAVYNDSDKNKMLPDMVEGDVVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLDVIQRRYYVRLVSKRFEPTELGEIVNNLIVEFFPDIVDVKFTADMEGKLDEVEEGKEQWQKVIDAFYKPFEKELAKAETEIEKIQIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPECHNTKAITKEIGVTCPICGEGQVIERKTKRNRLFYGCDRYPECEFTSWDKPVGRSCPKCGQFLVEKKIRGGGKQVVCSSEECDYEEAKVK
(1599) DNA topoisomerase 1 [Streptococcus mitis B6]
1
MATATKKKKSTAKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAISWHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTIDGVFKKGTKQFQASFYGVDGKKLKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGSKYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDYDKNKMLPDMAVGDVVKQVNSKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTELGEIVNKLIVDYFPDIVNVTFTAEMEGKLDDVEVGKEQWQRVIDAFYKPFSKEVAKAEEEMEKIQIKDEPAGFDCEVCSSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPSCHQGQIIERKTKRNRLFYGCNRYPDCEFTSWDKPVGRDCPKCGHFLMEKKVRGGGKQVVCSKGDYEEEKIK
(1763) DNA topoisomerase 1 [Streptococcus oralis Uo5]
1
MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAISWHLAHILDLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEINAFQPEEYWTIDGVFKKGTKQFQASFYGMNGKKMKLTTNEEVKEILSHLTSKDFTVDQVDKKERKRNAPLPYTTSTMQMDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASYINDRFGSKYSKHGSKIKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTGAIFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNSKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTELGEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWQRVIDAFYKPFSKEVAKAESEMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGNSMLVAISQTAVTHKLLSKRLESSVQAVIKDKSSNEKPSVIVSSMVAIAIQNVNLLPGTNQLDVIVQNADTSLWRKRSVAVVNRLYVVMATTKKRKLNNTKSPENKFQALFT
(240) DNA topoisomerase 1 [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
1
MGTKTTTKPKTGTKKSTTKKKSAAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHILGLDPEDKNRVVFNEITKDAVKNAFVEPRQIDMNLVDSQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFVPEEYWSIDGLFKKGTKKFQASFYGLDGKKMKLSNNDDVKAVLAKLKGDDFLVSKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFISNRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPEAIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKNKMLPEMEEGETVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPICHKGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRDCPKSGDYLVEKKVRGGGKQVVCSNETCDYKEEKIK
(1128) DNA topoisomerase [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
3
MTTVILAEKPSQARAYAVAFTQSQKGEGQIKVADPILPADTVITYGFGHLVEMALPEAYDASYKRWSLKKLPIFPDQYKYLVSRDKKKQFNIVANLLKRADTIVIATDSDREGENIAWSIMRQAGIDLKQKHLFRLWINSLEKAAIREGFQNLRPGWDYYYRYKEAQTRQISDWLVGMNGSPLFTLLLRKQGIKGTYSIGRVQTPTLYMVYKRDQEIANFKPEKYWLLMADFWQGRKKFTGRLLPETKFKSPAELEQFLLAKGGSLGKQTGRVAKVDKEQKSQASPRLFSLSSLQTEANRRYHASASQVLQAVQNLYENKFLSYPRTDCNYITDNEYAYLAQNLDRYQGLLPNSAEVKEQMKPLKAEKRYVDSGKVQEHHAIIMTKTVPSQAQMGKMSKLEGQVYGLVLRRTLEMFLKAYVYEKTTALINVGQLTFKASGNVSVNLGWKILEGPVKDAQLPSLEVGQELTAKLKEQEEETKPPAKFTEGSLITAMKTAGKTLDDEDAQATLKDVEGIGTEATRASTIEILKKRGYMQSRQNKLSVTPEGTILCKVAEAEPLLVSAQMTAQWEKALKQVGAKERSQDNFLGQIKKFISKMITEVPGKIQVDQGLQEEAQTRQAKTAAIGPCPVCKQGEITDKGKFYGCSNYRGGCHFTLPKKFAGKNMGKRIVKTLISKGKTDKLDGFISKKSGQRYSAKLQLEGDKLSLVFD
(1067) DNA topoisomerase 1 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
1
MPATAKEDKSKSSKKTTAAAKKSSPKRKKSKVKKDLVIVESPAKAHTIEKYLGRKYRVIASKGHIRDLPKSQMGVDIDHDYQPKYISIRGKGDTIKELKAEAKKANKVYLASDPDREGEAIAWHVAHVLGLDEKEANRVTFNEVTKDAVKDAFNHARTIDMDTVNAQQARRVLDRLVGYSLSPILWSKVKKGLSAGRVQSVALKLVIDREKEIKAFKPVEYWTIDAEFAKGKDKFQASFYGEEGKKTELPNNEAVQKLLAKFDKKQPFTVSKVVKREVRRQPAAPFTTSTMQQEANRRLNFRTSKTMNIAQHLYEGISLGKEGTVGLITYMRTDSKRISPVARQEAAQFIVEEYGSDFAVKKERHFKNQGDAQDAHEAVRPTSVYRTPKSLEKVLTKDELRLYTLIWSRFVASEMTPAVFDTVRYDLTQNGVTFRASGSVMKFAGYTKVYDNRSEKNVALPALEEGDEVKLTKSDNKQHFTQPPARYTEASLVRALEENGVGRPSTYAPTIQNIQSRNYVKLEGRAIVPTELGEIVDGLVEQFFPDITSVDYTAKLEDELDEVEEGKKDWVSVVDQYYKPFSKELEKADSEIQKIQIKDQPAGFDCEVCGAPMLVKMGRYGKFYGCSRFPDCRHTQTIVKKVGVTCPKCGEGEVLEKKSKRGRKFYGCSRYPDCDFVSWDKPISRVCPHDGHFLVEKKRKDGMVVLCPNGDYKEEPREEQGEAAE
(281) DNA topoisomerase [Streptococcus pasteurianus ATCC 43144]
3
MNAEVIVAPAVGHLVERINPYTNFENWEMANLPALPDGFAYEPKKDTAKRFKAIKQSVKEVDAIIIGTDPDREGEAIAYRILELIPGALRKIKYRLWANSLTKKGLEQAFSKLKNPKDSINYFHEADARGDADWLVGFNLSPFVTIKMKEEGYLDKKDHSMSVGRVQTPIVSLIVRNDEAIENFKPSPYWQLKLIDPEAKVTFGNDIKYQSKAEAELMLQQLANIAIVKTVTSEEKVQEAPKLYNLTNFQSEMSKLYHFDATKTKELVQSLYQKGYLSYPRTDSTLITTNEFAYLVEHIDDYQMAIHKQLETPNRSPRKNYVNDKKVLEHYAIIPTENIPDLNELSDDEKLIYQKVVFRTLLMFAPDYRYQSTSVILDNHGLEFKASGTVTKDNGWRNYLAAKKEDKELPHYQEGKNLVVDCKLLEEMTKPPTRITEQILLKKLLPKYNLGTSATRDGMIDLIQDKGYVTKNKKTGQFFPTERGKLLIHYLDQLEIAYTNPETTGKWEEVLAQIGQGKIQKEAFVNKIKWAITKQIEKGKQI
(1860) DNA topoisomerase 1 [Streptococcus salivarius 57.I]
1
MATATTTKTKTKTTKKTTAKKATKKRATPKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLINELKKEAKKAKQVFLASDPDREGEAISWHLSHILGLEPDDKNRVVFNEITKDAVKNAFVEPRAIDMDLVDAQQARRVLDRIVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWTIDGAFKKGAKKFQASFYGLDGKKLKLNNNDDVQAVLSRITSDDFNVDKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGINLGSGAQGLITYMRTDSTRISPVAQNQAAEFITERFGSKYSKHGSKVKNSSGAQDAHEAIRPSNVFQTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMKVTLSQNGVIFTANGSQIKFDGYMAVYNDSDKNKMLPDMAEGDTVKKVVTTPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLDVIQRRYYVKLVAKRFEPTELGEIVNSLIVEFFPDIVDVKFTAEMEGKLDKVEIGKEQWQKVIDEFFKPFQKELEKAEEGIEKIQIKDEPAGFDCDLCGHPMVIKLGRYGKFYACSNFPDCHNTKAITKEIGVTCPTCGKGQVIERKTKRNRVFYGCDRYPDCEFTSWDIPVGRNCPKSGDYLVEKKVRGGGKQVICSNEECDYKESIVK
(1537) DNA topoisomerase 1 [Streptococcus pneumoniae TIGR4]
1
MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAISWHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHASFYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGSKYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNSKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTELGEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEEEMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPSCHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQVVCSKGDYEEEKMALCQL
(915) DNA topoisomerase 1 [Lactococcus garvieae ATCC 49156]
1
MAKASEKQTTKKKKTSSKKTASKKKTKIVKGKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSTMSVDIDNDYEPQYINIRGKAPLINSLKKEAKAAKAVYLASDPDREGEAIAWHLAHILGLPLEDKNRVVFNEITKDAVKNAFKEPRSIDVDLVDAQQARRILDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIVDRENEINAFIPQEYWSIDGEFKKGAKKFKAAFWGVDGKKRALNNNDDVMEVMSRLSGPDFDVDKVEKKERRRNSPLPYTTSSMQQDAANKINFRTRKTMMVAQQLYEGLTLGAQGHQGLITYMRTDSTRISPVAQGVAADFITDRFGAKYSKHSSKVSNKAGAQDAHEAIRPTNVLNTPEAIAKYLDKDQLKLYTLIWNRFVASQMTAAIFDTMKVNLSQNGVIFIANGSQVKFDGYLAIYNDSEKNNMLPDIAAGDVVKKANLKPEQHFTQPPARYSEATLIKVLEENGVGRPSTYAPTLETIQKRYYARLVAKRFEPTELGEIVNKLVVEFFPNIVNTEFTAEMEKDLDKVEEGQRRWVDVVDQFYKPFAVELEKAEVEMEKIVIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPECHNTKAIVKEIGVTCPSCHKGQIIERKTKKNRLFYGCDRYPECEFTSWDKPVGRSCPKCEHYLVEKKVRGGGKQVVCSNETCDYKEEKQK
(916) DNA topoisomerase 1 [Lactococcus garvieae ATCC 49156]
1
MAKASEKQTTKKKKTSSKKTASKKKTKIVKGKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSTMSVDIDNDYEPQYINIRGKAPLINSLKKEAKAAKAVYLASDPDREGEAIAWHLAHILGLPLEDKNRVVFNEITKDAVKNAFKEPRSIDVDLVDAQQARRILDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIVDRENEINAFIPQEYWSIDGEFKKGAKKFKAAFWGVDGKKRALNNNDDVMEVMSRLSGPDFDVDKVEKKERRRNSPLPYTTSSMQQDAANKINFRTRKTMMVAQQLYEGLTLGAQGHQGLITYMRTDSTRISPVAQGVAADFITDRFGAKYSKHSSKVSNKAGAQDAHEAIRPTNVLNTPEAIAKYLDKDQLKLYTLIWNRFVASQMTAAIFDTMKVNLSQNGVIFIANGSQVKFDGYLAIYNDSEKNNMLPDIAAGDVVKKANLKPEQHFTQPPARYSEATLIKVLEENGVGRPSTYAPTLETIQKRYYARLVAKRFEPTELGEIVNKLVVEFFPNIVNTEFTAEMEKDLDKVEEGQRRWVDVVDQFYKPFAVELEKAEVEMEKIVIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPECHNTKAIVKEIGVTCPSCHKGQIIERKTKKNRLFYGCDRYPECEFTSWDKPVGRSCPKCEHYLVEKKVRGGGKQVVCSNETCDYKEEKQK
(917) DNA topoisomerase 1 [Lactococcus garvieae ATCC 49156]
1
MAKASEKQTTKKKKTSSKKTASKKKTKIVKGKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSTMSVDIDNDYEPQYINIRGKAPLINSLKKEAKAAKAVYLASDPDREGEAIAWHLAHILGLPLEDKNRVVFNEITKDAVKNAFKEPRSIDVDLVDAQQARRILDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIVDRENEINAFIPQEYWSIDGEFKKGAKKFKAAFWGVDGKKRALNNNDDVMEVMSRLSGPDFDVDKVEKKERRRNSPLPYTTSSMQQDAANKINFRTRKTMMVAQQLYEGLTLGAQGHQGLITYMRTDSTRISPVAQGVAADFITDRFGAKYSKHSSKVSNKAGAQDAHEAIRPTNVLNTPEAIAKYLDKDQLKLYTLIWNRFVASQMTAAIFDTMKVNLSQNGVIFIANGSQVKFDGYLAIYNDSEKNNMLPDIAAGDVVKKANLKPEQHFTQPPARYSEATLIKVLEENGVGRPSTYAPTLETIQKRYYARLVAKRFEPTELGEIVNKLVVEFFPNIVNTEFTAEMEKDLDKVEEGQRRWVDVVDQFYKPFAVELEKAEVEMEKIVIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPECHNTKAIVKEIGVTCPSCHKGQIIERKTKKNRLFYGCDRYPECEFTSWDKPVGRSCPKCEHYLVEKKVRGGGKQVVCSNETCDYKEEKQK
(347) DNA topoisomerase 1 [Lactobacillus buchneri NRRL B-30929]
1
MATSTKTKPKAKAKSKTKRKSPKKNLVIVESPAKAKTIEKYLGRSYKVVASKGHVRDLPKSKMGVDIDHDYEPHYISIRGKGDTIKELRSAAKKAKKVYLAADPDREGESIAWHLQHILDLDPNEDNRVVFNEITKDAVKESFKHPRNIDMNLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALWLIIQREKAIKDFTPEEYWSIDSEFKKGRSKFKAAFYGLNGKKKELPNNEAVQKVLQQLDPKGDFDITKVTRRERKRQPQPPFTTSTMQQEANRKLNFRTRKTMMAAQQLYEGINIGKEGSQGLITYMRTDSTRISVIAKHEASQFLHEKYGAEYAATKPIKGKLPEGAQDAHEAIRPTSVFRTPASLKQYLTRDQFRLYQMVWSRFVASQMTPAIMDTMAVTIEQNNVTFKANGSKMKFDGFLKVYGDSKEKDNLLPDLESSDVVKLVKNNPDQHFTQPPARYSEATLIKALEEKGVGRPSTYSPTIDTIQRRYYVKEVGRRFEPTELGEIVNKIIVEYFPDVVNIDFTANLEGKLDQVEEGKENWIKLVDTFYKPFSDEVDAATKNMEKVQIKDEPAGINCEICGAPMVIKMGRYGKFYACSRFPDCRNTKAIVKEIGVICPKCHKGQVIERKSRKNRIFYGCSRYPDCDFVSWDKPIGRDCPKDGHFLVEKRVKGGTQVVCPNGDYEEPAQK
(273) DNA topoisomerase 1 [Lactobacillus helveticus DPC 4571]
1
MPTKAKSKSKTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHIAHALNLDENAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWTIDAEFAKDKEKFKSAFYGVDGKKKELPNIDAVKDVLAKIDKKKNFTVEKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKNQRHFKNQEDAQDAHEAIRPTSVYRTPESLKDVLTKEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKMKFAGFTKVYDNQQEKNVELPDLQEGDQVKMTKSDNKQHFTLPPARYTEASLVHALEKNGVGRPSTYVPTIDTIQRRYYVKLDGRSIVPTELGEIVDTLVEEFFPDIANVDYTAHLENELDEVEDGKKQWVNVVDEYYQPFKKELNKADSEIQKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVVCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVTLCPNGDYREEPQENEDK
(1107) Uncharacterized protein [Lactobacillus reuteri SD2112]
1
MATKTTKSTAKKTTRRRSKIKKNLVIVESPSKAKTIGKFLGRSYKVVASLGHIRDLPKKPDGGRY
(1379) DNA topoisomerase 1 [Lactobacillus amylovorus GRL 1112]
1
MPTKAKSKPKTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFDDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHVAHALNLDENAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKEFKPKEYWSIDADFKKGKDSFKSAFYGVDSKKKELPNIDAVKEVLAKIDKKKDFEVAKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRISPVAQQEASKFLHEKYGAEYAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFVASEMKPAVYDTVRADIVQNGVMFRTTGSKMKFAGFTQVYDNQQEKNVDLPDLEEGDKVQMTKSDNKQHFTQPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLEGRSIVPTELGEIVDTLIEQFFPDIANVDYTAHLEDELDEVEDGKKQWVNVVDEYYQPFKKELDKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVVCPKCGKGQVVEKKSRRNRKFYGCSRYPDCDFVSWDKPIGRNCPNDGHFLVEKRSKKGPVILCPNGDYREDPQEDEIDK
(214) DNA topoisomerase [Lactobacillus salivarius UCC118]
7
MKKLILAEKPSVARDIGRILNANEKKKNYLEGKNYIITWALGHLLGLKMPEDLNKKWEKWQLETLPMLPKFIGIKPLPKTRGQLKTIESLVKRKDINEIVIATDAGREGELVARWILQYVHANKKVTRLWISSQTDKAVKQGFKELKPAEKYDNLYESALARATADWLVGLNVTRALTVKYQDNLSAGRVQTPTLALVRRQEEKIEKFMPQKYYRIALRIGKQTAYMKQKNIYAIKERDEAEKKKRHLDNFKGQIKDINSKIKREPAPLLYDLTELQREANKRYGYSAKKTLSLVQSLYEIHKVVSYPRTDSRYLSNDIKATLMERLQAIRKYDSRAEEAIKNKAKVILKKVFNDSKVTDHHALIPTEQVPNYSKFSADEQKIYNLIVSRFLGIFAQPYTVEELRVVVTFDKDEFIFVGKKVLDYGWKNKDAAEEVVLNLKKDTAVSPNFTVEEKLTTPPAPLTEAGLLAQMEKFGLGTPATRAEIIEKLVKSELMERTGHALRVTPKGKQLLNLVNKELVSPKLTAKWEKQLEDIAHGKMKSQKFIGDIKNDTKRLVSEVKNSKEDYKDFSLTKKRCPECNSFLKVRKTRDGEIYVCSNPECNYRRRKDAKVSNHRCPQCHRKMLIVEGKNGKYFRCKYDGTTEKMTVGKKSKKMTKHEERRLLKKINQDDEPQESPLALALKAAMGKNE
(1686) DNA topoisomerase 1 [Lactobacillus salivarius UCC118]
1
MPTTQKPKKKTTKRTRKKNLVIVESPSKAKTIEKYLGSNYKVMASLGHIRDLPKSKMGIDVENGYEPHYISIRGKGDVIKELRKEAKKASHVYLAADPDREGEAIAWHLSYLLGLNPEDKNRVVFNEITKDAVKNAFKSPRSIDMNLVDAQQARRVLDRLVGYSISPLLWSKIKKGLSAGRVQSIALNLIIQREKEIRDFKPEEYWTIDAKFKKGRTKFEADFWGVDNKKKKLSNEKDVKEVIEKIDKDKPFNVINIEQKERKRMPPLPFTTSAMQQTANNNLKFRTQKTMMVAQQLYEGINIGRGGAVGLITYMRTDSTRISSVAKHEAAVFLHENYGEEYAASKPRQGKLSENAQDAHEAIRPSSVERTPEKMAKYLDKDQLKLYTLIWSRFVASQMTPAVFDTMRVDIEQNGVQYRANGSKMKFPGFIKVYKAATSKDNLLPELKVGDEVDMVQNQPNQHFTLPPARYSEATLIRTLEENGVGRPSTYAPTLSTIQKRYYVKLVSRKFEPTELGEIVNSMIEECFPDILNVDFTAHLEDQLDDVEEGKEEWVRIIDEFYQPFSKEVDNAQVKMDKIKIKDEPAGIDCEICGAPMVIKLGRYGKFYACSRFPDCRNTKAIVKEIGVVCPKCHKGQIIERKSKKNRVFYGCSLYPDCDFVSWDKPIGRDCPKCSHYLVEKKTKKGMQVKCSNCDYEEAIQNN
(1657) DNA topoisomerase 1 [Pediococcus claussenii ATCC BAA-344]
1
MPTAKKNLVIVESPSKAKTIEKYLGRSYKVIASLGHIRDLPKSKMGVDIDNNYDPHYISIRGKGDTIKKLRTEAKKAKKVYLASDPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDAVKNAFKTPRSIDTSLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALSLIIKREQEIRDFKPEEYWSIDSEFKKGRSKFNASFYGTGGKKKALKNEKAVQKILKLINPKDDFDVTSVKRKERKRFPSPAFTTSSLQQEANKTLNFRTRKTMMAAQQLYEGINIGKEGTVGLITYMRTDSTRISDIAKHEASVLIHEKYGAEYAAIKPRKGKMPEGAQDAHEAIRPSSVNRTPEDLKEYLSKDQYRLYNLIWSRFMASQMTPEVSDTMAVTIEQNDVQYRANGSKTKFEGFTKVYKTNKEKDNSLPAMEEGDKVKLVSNNPNQHFTQPPARYSEANLVKALEENGVGRPSTYAPTLDTIQKRYYVKLESRRFEPTELGEIVNDIIYEFFPDIVNIDFTAHLETELDEIEEGKEDWVKVVDGYYKPFSKEVDTAQEQIEKVQIKDELAGFDCEVCGSPMVVKMGKYGKFFACSRFPDCRNTQAIVKEIGVTCPKCGIGQIIERKSKRGRLFYGCSRYPDCDFVSWDKPVGRKCPVCHSFLVEKKIKGGKQVVCPNGDYEETPQK
(1042) DNA topoisomerase [Pediococcus claussenii ATCC BAA-344]
7
MKKKLIITEKPSVATDLARVLGVEQKNKTYYEGNNYIITWAYGHLLTLKLPEDINKDWQNWDLNDLPIIPKNIGIKPLPKTKQQLKAISRLAKRTDVESAIIATDSGREGEAVARYILEWIRFNKPVERLWISSQTTKAIREGFSNLRPAEQFDDLYASALARGKADWLVGLNVTRALTTKYKDNLSAGRVQTPTLSFIWKQEQEINSFRPHKFYKIYLVYQGQTADLLLKNSEQFETREQAEKVVQGLQKKSGLVEDLKVKQNMQDAPLPYDLTELQRTANSMYAFSAKKTLSIVQSLYEVHKIVSYPRTDSKYLSTDIKDTLKERLSALSGFDSQAKAYLRRGAKIVQRSVFNDQKVTDHYALIPTEESVQPAKLSSDELRIFRLIEKRFLGLFAEKFITETTNTTIGFGSAKFVFKQTRVVKPGWRFDLETETKKTKVQLKLKQQIEGQFIIKEKLTTPPKPLTEGTLLGKMEKFGLGTPATRAEIIEKLTQSELVKRTNGALITTPKGQQLLKLVNKSLASPDLTSKWEKSLESIAHGKVNYMDFVKDVEKETRRLVSEIKTSEIEYRDFGVTNKLCPECGYALKERNSRDGKILTCSHCGYRRRKDPKVSNHRCPQCHKKMVILEKNGQSYFRCLNDGTTEKMLDKKERKKKISKKEERKLLSKINNEDPEESPLAIAMKKAMEK
(1197) DNA topoisomerase [Carnobacterium sp. 17-4]
1
MEKVKKGLSAGRVQSVALKLICEREDEINRFEPEEYWSIGANFKKDKKKFKANFYGLKGKKQALSNAEDVQKIIKELDGDQFEVMSVTKKERLRNPALPFKTSSLQQEAARKLNFRTRKTMMVAQQLYEGISLGRGGAVGLITYMRTDSTRIALSAKNEAAEYIIKEFGPEYAASKPRIGKKAEGDQDAHEGIRPSSVLRTPKEVEKYLTKDQYKLYNLIWSRLVASQMTPAVFDTMKVDIAQKDVYFRANGSKVKFPGYQKVYIEGNDEGKEEKDNLLPEMEKGDKVKSIDIEPKQHFTQPPARFSESTLIRVLEDNGVGRPSTYAPTLETIQRRYYVKLQNKRFEVTELGGIVNGLINEFFPQIVDVHFTADMEKNLDEVEEGNKEWEKVIDQFYQPFAVEVEKAEENMEKVQIKDEPAGFDCELCGHPMVIKLGRYGKFYACSNFPDCRNTKPIVKEIGVACPVCGEGHVIERKSKKNRIFYGCDRYPTCEFVSWDKPVGRSCPKCEHYLVEKKAKGSKQVICSNCDYKEEVQK
(1700) DNA topoisomerase [Carnobacterium sp. 17-4]
7
MKTLIIAEKPSVGKEIARVLGATQKSKTHIEGKDVIVTWALGHLLGLKMPEDYKAEWATWDLNALPLIPEKMTTKPLTNTRGQLKAIKQLANRKDIGSAVIATDAGREGELVARWILEYVNFNKPVKRLWISSQTDKAIKDGFNQLQPSKKYDTLYDSAVARSEADWLIGLNVTRALTVKYQDNLSAGRVQTPTLAMVRKQEAKIQSFVPETFYTVQLTVDGKKAVLQEGAPRKFNDREKAEALVSSLKDKPITVVDIKEKQSVQQAPMPYDLTELQREANQRYQFSAKKTLSLMQTLYERHKVLSYPRTDSKYLTQDMVGTLKERVMAIQGFAPEEAKGILKRGAQVTQKGVFNTAKVTDHHGIIPTEERPRPEKMEADELKIYRMVVERFIGLFLPAYKVSKTTIVFSAADVLFSLQQETVLEKGWKKDVPKQSENVYKLNEQLMRTAYTIQKQLTEAPTRLSEGTLLQNMEKNGLGTPATRAEIIEKLISSELMERNQNKLSTTPKGQQLLTLVNPALVTPELTSKWEKSLEEISNGGLKKEDFLKNIKQETARLVTEIKTSTQTYKDHALTSKICPECGELLKERSGRDWKLLICSSSTCSYKRRKDPKVSNHRCAQCHRKMEIHEGKNGNYFKCKYCNITEKLEGKSSKKPSKHETKKLMQKINNQQEEVESPLALAMKAAMAKKE
(441) DNA topoisomerase [Carnobacterium sp. 17-4]
3
MDQSMGHTVILAEKPSQAQAYAESFGKFSKKDGYIVLNSSNDVITWGFGHLVELASPEEYKDEWKKWNMKELPIIPEIFKFKVGQGKAKQFNVVKKLLQEADQIIIATDSDREGENIARSIINQAKAGNKEIKRLWINSLESDEIQKGFSDLRDGREFYSSYIEAQTRQISDWLVGINLSRMYTLSLQKKGINEGVFSVGRVQTPTLYMIYTRQKQIENFIPEPFFELHATVKAENGLFKAKYSKKFSTKKELQELIQKHGLLASNPGMISSVETKRISQPSPFLFSLSDLQSLVNKKYKVSPSDTLKHVQSLYEAKLVSYPRSDCRYITDSEFRYLLERIEGYQGILNHTIKEPNTSKRKRYVDGSKVQEHYAIIPTKKVPTQKALEKLPSIQREIYFTILRRSMAMFETDYKYDETTVTVDIKTVPFISKGKVILDKGWQRLEYGASKKSNKETTSELPLVKKGELVEADLNTSEGFTSPPKTYTEGTLITAMKTCGKELENEEEKEILKATEGIGTEATRANVLETLKKQNYIEIQKNNVTVTQKGEILCQAVENTLLSSPEMTAKWETYLKKIKNEDGTQQAFLDSIQKFIAHTLDSSAQVIEKRDWSTHTNSINHLSQKTIGKCPVCGQMMIDKGKFYGCSGYSNGCTFTLPKRYVGKTLSEATLKKLLDTRETQLLKGFKKKTGQTFSAALILTEDNKLLFKPYEKTEKK
(839) DNA topoisomerase 1 [Enterococcus faecalis V583]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLPKSKMGIDIENNYEPHYISIRGKGDVIKSLKAAAKKAEKVYLAADPDREGEAIAWHLAYLLGLDLKDKNRVVFNEITKEAVKAAFKEPRTINVDLVDAQQARRILDRLVGYSISPILWRKVKKGLSAGRVQSVALKMIIDRENEIREFKPEEYWSIDGNFQKGRKKFKANFWGVDGKKKKLPNAEAVKEITSRIDGKDYDVTKVEKKERKRNPALPFTTSSLQQEAARKLNFRTRKTMMVAQQLYEGIALGKQGTVGLITYMRTDSTRIADSAKAEAAEFIEKTYGDEFSAHGGRKAKNTQGAQDAHEAVRPSSVLRTPDEMKKYLDKDQLKLYTLIWSRFVASQMTPAILDTMKVTLQQNGVTFIANGSKVKFKGFMQVYVEGRDDGKEDKENILPELVEGDVVKSVDIEPKQHFTQPPARFSEATLIRTLEENGVGRPSTYAPTLETIQRRYYVKLTNKRFEPTELGEIVNSLVSEFFPQIVDTHFTATMETDLDKVGEGQEKWVEVVDRFYKPFEKELTNAEEKIEKIQIKDEPAGFDCELCGHPMVIKLGRYGKFYACSNFPDCRNTKAIVKEIGVTCPVCHEGQVIERKSKKNRIFYGCSRYPECDFTSWDKPVGRPCPKCGQYLVEKKVKGGKQVVCINGDYEENVQK
(1315) DNA topoisomerase [Enterococcus faecalis V583]
7
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLSVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
(25) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(26) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(841) DNA topoisomerase 1 [Enterococcus faecalis V583]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLPKSKMGIDIENNYEPHYISIRGKGDVIKSLKAAAKKAEKVYLAADPDREGEAIAWHLAYLLGLDLKDKNRVVFNEITKEAVKAAFKEPRTINVDLVDAQQARRILDRLVGYSISPILWRKVKKGLSAGRVQSVALKMIIDRENEIREFKPEEYWSIDGNFQKGRKKFKANFWGVDGKKKKLPNAEAVKEITSRIDGKDYDVTKVEKKERKRNPALPFTTSSLQQEAARKLNFRTRKTMMVAQQLYEGIALGKQGTVGLITYMRTDSTRIADSAKAEAAEFIEKTYGDEFSAHGGRKAKNTQGAQDAHEAVRPSSVLRTPDEMKKYLDKDQLKLYTLIWSRFVASQMTPAILDTMKVTLQQNGVTFIANGSKVKFKGFMQVYVEGRDDGKEDKENILPELVEGDVVKSVDIEPKQHFTQPPARFSEATLIRTLEENGVGRPSTYAPTLETIQRRYYVKLTNKRFEPTELGEIVNSLVSEFFPQIVDTHFTATMETDLDKVGEGQEKWVEVVDRFYKPFEKELTNAEEKIEKIQIKDEPAGFDCELCGHPMVIKLGRYGKFYACSNFPDCRNTKAIVKEIGVTCPVCHEGQVIERKSKKNRIFYGCSRYPECDFTSWDKPVGRPCPKCGQYLVEKKVKGGKQVVCINGDYEENVQK
(27) DNA topoisomerase III [Enterococcus faecalis V583]
7
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
(1317) DNA topoisomerase [Enterococcus faecalis V583]
7
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLSVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
(840) DNA topoisomerase 1 [Enterococcus faecalis V583]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLPKSKMGIDIENNYEPHYISIRGKGDVIKSLKAAAKKAEKVYLAADPDREGEAIAWHLAYLLGLDLKDKNRVVFNEITKEAVKAAFKEPRTINVDLVDAQQARRILDRLVGYSISPILWRKVKKGLSAGRVQSVALKMIIDRENEIREFKPEEYWSIDGNFQKGRKKFKANFWGVDGKKKKLPNAEAVKEITSRIDGKDYDVTKVEKKERKRNPALPFTTSSLQQEAARKLNFRTRKTMMVAQQLYEGIALGKQGTVGLITYMRTDSTRIADSAKAEAAEFIEKTYGDEFSAHGGRKAKNTQGAQDAHEAVRPSSVLRTPDEMKKYLDKDQLKLYTLIWSRFVASQMTPAILDTMKVTLQQNGVTFIANGSKVKFKGFMQVYVEGRDDGKEDKENILPELVEGDVVKSVDIEPKQHFTQPPARFSEATLIRTLEENGVGRPSTYAPTLETIQRRYYVKLTNKRFEPTELGEIVNSLVSEFFPQIVDTHFTATMETDLDKVGEGQEKWVEVVDRFYKPFEKELTNAEEKIEKIQIKDEPAGFDCELCGHPMVIKLGRYGKFYACSNFPDCRNTKAIVKEIGVTCPVCHEGQVIERKSKKNRIFYGCSRYPECDFTSWDKPVGRPCPKCGQYLVEKKVKGGKQVVCINGDYEENVQK
(1316) DNA topoisomerase [Enterococcus faecalis V583]
7
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLSVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
(1550) DNA topoisomerase 1 [Enterococcus sp. 7L76]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLPKSKMGIDIENNYEPHYISIRGKGDVIKSLKAAAKKAEKVYLAADPDREGEAIAWHLAYLLGLDLKDKNRVVFNEITKEAVKAAFKEPRTINVDLVDAQQARRILDRLVGYSISPILWRKVKKGLSAGRVQSVALKMIIDRENEIREFKPEEYWSIDGNFQKGRKKFKANFWGVDGKKKKLPNAEAVKEITSRIDGKDYDVTKVEKKERKRNPALPFTTSSLQQEAARKLNFRTRKTMMVAQQLYEGIALGKQGTVGLITYMRTDSTRIADSAKAEAAEFIEKTYGDEFSAHGGRKAKNTQGAQDAHEAVRPSSVLRTPDEMKKYLDKDQLKLYTLIWSRFVASQMTPAILDTMKVTLQQNGVTFIANGSKVKFKGFMQVYVEGRDDGKEDKENILPELVEGDVVKSVDIEPKQHFTQPPARFSEATLIRTLEENGVGRPSTYAPTLETIQRRYYVKLTNKRFEPTELGEIVNSLVSEFFPQIVDTHFTATMETDLDKVGEGQKNGLKLSIASTSPSKKN
(1313) DNA topoisomerase [Enterococcus sp. 7L76]
7
MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDSLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEASINVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGEHAEVDVKSAEKETQPPKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFINNIKKFIVHLLEAVPTDIEKLSFADYQVQKEKEAEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK
(1719) DNA topoisomerase [Melissococcus plutonius DAT561]
7
MIKKQLIIAEKPSVAKDLSKVLGANQKNKGYFEGDTAIVTWALGHLLGLKMPEEINKEWQSWQMTTLPMLPKHLGIKPLPKTGQQLKTIKQLVNRKDIKEIVIATDAGREGELVARWILEYTHVTKPIKRLWISSQTDKAIKEGFKHLRPAKEYDHLYYSALARAKADWLVGLNVTRALTVKYQDSLSAGRVQTPTLALVRQQEKDISAFQAQTYFTISLQVADEKAKMVQKNPYSLKTRNEAELLVNKWNQQIGKVTDIKEKLKVESAPLPYDLTEIQKEANQRYQFSAKKTLSLVQSLYEVHKIVTYPRTDSKYLTTDMKETMNERLLAIREFDPIVKEYIKTGSQVKQTKVFQNAKVTDHHGLIPTEQRPNYTKLSNDEQKIYTMIVYRFLSLFAGPYKVAQTKITVTFGEQSFIFNQNKVESLGWRRETLEEKKKVSWKIGMTVSPKFSIQKELTSPPKPLTEGTLLAKMEKYSLGTPATRAEIIEKLIRSELMERTSQGIAVSPKGRQLLELVNPSLVTPELTEKWEKELEAIALGKQSSQNFLKEIETDTKKLVSEIKNSQKSYQDFSITQKKCPECQTNLKEKNTKEGKIYSCPNSECSYRRRKDPKLSNHRCPQCHKKMLIMDNQKNAYFKCKYCSITEKMLDKKNKKQKLTKQEERRLMKKYTKSETPQESALAQALKAAMSEKNPNH
(434) DNA topoisomerase 1 [Melissococcus plutonius DAT561]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLPKSKMGIDIENDYAPHYISIRGKGDVIKSLKTAAKKADKVYLAADPDREGEAIAWHLSYLLGLDPNEKNRVVFNEITKEAVKAAFKEPRTINLDLVNAQQARRILDRLVGYSISPILWRKVKKGLSAGRVQSVALKIIIDREKEIKEFIPEEYWTIDGNFQKGRKKFKASFWGIEGKKKKLPKADSVKEITDKLKDDKYQVTKVEKKERKRNPALPFTTSSLQQEAARKLNFRTRKTMMIAQQLYEGISLGKKQGTVGLITYMRTDSTRIAASAKVEATEYIEQTYGKEFSIQEERKVKKAQGTQDAHEAVRPSSVLRTPDSIKEYLNKDQLKLYTLIWSRFLASQMAPALLDTMKVTLEQNQVMFIANGSKIKFKGFMQVYIEGRDDGKEEKENILPELVEGDSVTSINIEPKQHFTQPPARFSEATLIHNLEENGVGRPSTYAPTLETIQKRYYVKLTNKRFEPTELGEIINTLIVDFFPQIVDVHFTAAMEEDLDKIGDGKEEWITVVDRFYQPFEKELTNAEEKIEKIQIKDEPAGFSCEECDHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVRCPICHEGQVIERKSKKNKLFYGCSRYPDCDFTSWDKPVGRLCPKCGKYLVEKKVKGGKQVVCINGDYEENVQK
(1759) DNA topoisomerase 1 [Tetragenococcus halophilus NBRC 12172]
1
MAYKYLVIVESPAKAKTIEKYLGRNYKVVASVGHVRDLPKSKMGIDVENNYEPYYITIRGKGDVIKDLKKHAKKAERVYLASDPDREGEAIAWHLSYILGLDPHDKNRVVFNEITKDAVKEAFKEPRTIDLDLIDAQQARRVLDRLVGYSISPILWRKVKKGLSAGRVQSVALKMIIDREKEIRNFTPEEYWSIDGNFKKGRKKFKANFWGLDGKKKKLPNEDAVKEVTQRISGKDYNVTKVEKKERKRNPAAPFTTSSMQQEAARKLNFRTGKTMMVAQQLYEGISLGKGGTTGLITYMRTDSKRISDTAKQEATDFIEQTYGKNYAAHSNKKLKNAQGAQDAHEAIRPTSAMRSPEEIGKYLDKDQLKLYRLIWSRLIASQMKPAILDTVKATLDQNGVIFVANGSKVKFKGFMEVYVEGRDDGKKDKENVLPELASGDIVQSEDITPNQHFTQPPARFSEATLIRTLEENGVGRPSTYAPTLQTIQKRYYVKLTQKRFEPTELGEIVDNLIEDFFPEIVDASFTAGMEEDLDHIEEGKEEWVKVIDRFYQPFEKELETAEEKMEKIEIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPECRNTKPIVKEIGVTCPKCQKGQVIERKSKKNRIFYGCDRYPDCDFISWNKPIGRNCPKCDHYLVEKKKKASKQVVCSNCDYKEDEQK
(585) DNA topoisomerase [Tetragenococcus halophilus NBRC 12172]
7
MKQLILAEKPSVAKDLGRVLGANKKTKNYYEGPNVIVTWALGHLLGLKMPEDINKNWQTWQMETLPMIPKNIGIKPLPKTGQQLKAIKQLAHRKDIKEFVIATDAGREGELVARWILEWVHFDKPVKRLWISSQTNKAIKEGFKQLKPAKEYDALYESALARSKADWLVGLNISRALTVKYEDSLSAGRVQTPTLSFVRQQEKQIDKFRPQTYYVIELEVAGQKAARIQKNPYEIKEQQEAQNLITQMSQHAGAVVSVNEKNKTENAPLPYDLTEIQREANQRYGFSAKKTLSVVQSLYETHKVVTYPRTDSKYLTNDMKKTMKERLQAIANFSPEVKDYIKSGAKVEQKAVFNDAKVSDHSGLIPTEQGANPAKFSNDEQKIYNMIVTRFLTLFAKAHKKLQQKATVKFGDETFVFTQNKIIEAGWKGQEESEKNVNKWQEGQKIQPNFSIKKELTKPPKPLNEASLLAKMEKFSLGTPATRAEIIDKLLRSELMERTPSGLQVSPKGKQLLDLVNPSLVTPDLTKKWEEELEAIAQNKFSSKKFLAQIEKDTKELVNEVKNSQKKYQDFSITQKKCPECRSFLREKNTRNGKIYVCSNSECSYHRRKDPKVSNHRCPQCHKKMEIIEGKNGAYFRCKFDGITEKIPNKKEQKKKMSKQEEKRLLKQYSKPDEPEESPLAIAMKEAMNKD
(1062) DNA topoisomerase [Tetragenococcus halophilus NBRC 12172]
7
MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPILPDRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQDTFSLGRVQTPTLYLIFQRQEATENFKKEPFFEVEASIKVNQGSFKGVLSPTQHFKTQEELLAFVSSKQAKIGNQEGIIADVRTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPNESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVDVKSVEKETQPPKAFTEGTLLTAMKTANKTVDNEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWEIIESEQVIVRKDRLPAHFL
(1034) DNA topoisomerase 1 [Leuconostoc sp. C2]
1
MVEPGKVAKKPAAKKTTKRKKSKNQKKLVVVESPAKAKTIEKYLGSTYKVVASLGHIRDLPKSTLGVDVDNDYDPKYINIRGKGDLIKGLRKEAKAAKVVYLASDPDREGEAISWHLQHILGLDPDQPNRVVFNEITKDAIKNAFKTPRKINQDLVDAQQARRILDRLVGYSISPILWKTVKRGLSAGRVQSVALGLIIAREREIQAFEPEEYWSLDSEFQKSRQKFKATFYGFDAKKQVLPDNDSVQSVLKNIDQSADFDVMKVNAKERKRNPQPAFTTATMQQTANTQLNFRTRKTMMAAQQLYEGINLGRGIGQIGLITYMRTDSTRISSVARHAAAVYIHDTWGEEYSQHKLVQGKLPEGAQDAHEAIRPSDVTITPSSIKDKLTPDQFKLYSLIWSRFVASQMTPEILDTMAVTIEQNGVIFRANGSKTKFQGFTKAYPAAKEKDNALPDLAEGDRVKLANINPEQHFTLPPARYSEAALIKALEENGVGRPSTYAPTLDTIQRRNYVRIDARKFVPTELGEIVQTIVENSFPDVTNMKFTARVEHELDEIETGDKQWVPVIDSFFKPFSKELEIAETTLEKVVMHDELAGMDCDICGAPMLVKMGRYGKFHACSRFPDCRHTQTIVKEIGLICPKCGKGQIIERKTKRQRTFYGCSRYPDCDFVSWEKPTEKTLPDGTTPKDDEMSDGQQNSQQPTDNKEEAT
(1858) Topoisomerase IA [Leuconostoc sp. C2]
3
MPNYLILTEKPSAAANFVKALGGKTGTFNNFTYKITNLRGHVMTLKDPEEMVAEDLKKQYKSWLVKHLPWDLNDFSWERTYIRQRNMRTGKTESTKKIIDELKKEAKTGYDAIVIATDTDPSGEGELLAWEALDAIKWRGQVLRANFMDESATGVKTAMMNLRDVSDKQQDGEYIKGESRNRWDFASMQLTRIATTAAKKQGFKVVAREGRLKSVIVWQIYAQLLAIKNYVKKPYFEVKFKDPAGHIFGRVTPDGDVIPWRFSTKNDAQKDMTQYHESAVANEKHQTRTQAPGKLLDLAGLAAILAPRGFSAKEVLSTYQKMYEAQVVSYPRTEDKTVTPEQFNELLPKIDQIAQLVQVDTRLLTHRQPRPTHVKKQGAHGANRPGENIPTSLTSLTKFGPSAQAIYDILAKNYLAMLAEDYVYDHVTADLQDYPRFKTAFNIPIEMNFKAVYDSQRAVKVEDEVEDDNSGQLGPNAQPYLYEGANKKPQTPTTKWIMAFLEKHHVGTGATRVSTLSDMSRGTKSMIKETRGKLMLTETGNVSAVMVKDTWIASPKITKRLFEMMDQVGQFEITMPKLLDSITQVVEHDMPIMLSNADELELLLGKPKPALKRPVTEKITGVFKGEEITFAKSWSGHSFTDDELTKLLNGDEISFDAKSKRGKSYTAIGKMAKQTFKGRTFYGFKLNPK
(1270) DNA topoisomerase 1 [Leuconostoc mesenteroides subsp. mesenteroides J18]
1
MAETKTATKKKKAAPRKKSKIKKNLVIVESPSKAKTIEKYLGRNYKVVASLGHIRDLPKSTLGVDVENDYDPKYINIRGKGDVIKGLRKEAKAAKAVYLASDPDREGEAIAWHLQHILDLNPEQPNRVVFNEITKDTIKNSFKTPRVINQDLVDAQQARRILDRLVGYSISPILWKTVKRGLSAGRVQSVALGLIIAREREIQAFQPEEYWTLDSMFKKNRTKFKSIFYGFDGKKQPLPDNDSVQDVLKRINKDGDFDIVKVDTKQRKRQPQPPFTTSTMQQTANTQLKFRTRKTMMAAQQLYEGINLGKGLGQVGLITYMRTDSTRISSVAKNAAAQFIHDTWGEEYSQHKPVQGKLQEGAQDAHEAIRPSDVNRTPESIKDKLTPDQFKLYSLIWSRFVASQMTPEILDTMAVTIEQNGVIFRANGSKTNFEGFTKAYPTAKKKDNVLPSLSEGDKVSLANTDPEQHFTLPPARYSEATLIKALEENGVGRPSTYAPTLDTIQRRNYVRIDARKFVPTELGEIVQTIVEESFPDVTNMKFTAAVEHELDEVETGNKHWVPVIDSFFKPFQKEVEKAETSLEKIIMHDELAGMDCEVCGAPMLVKMGRYGKFYACARFPDCRNTKAIVQEIGLLCPKCHKGQIVQRKTKRGRTFYGCQRYPDCDFVTWDKPTEKTLADGTTPKDDEKKEPVKK
(1176) DNA topoisomerase 1 [Leuconostoc gasicomitatum LMG 18811]
1
MVETKNKTTKLVTKKTTKRKRAKVKKNLVIVESPSKAKTIEKYLGSSYKVVASLGHIRDLPKSTLGVDVENDYDPKYINIRGKGDVIKGLRKEAKAAKKVYLASDPDREGEAIAWHLQHILELNPEEPNRVVFNEITKDTIKNAFKIPRKINQDLVDAQQARRILDRLVGYSISPILWKTVKRGLSAGRVQSVALGLIISRERKIQAFEPEEYWTLDSEFKKSRSKFKSSFYGFDGKKQPLPDNESVQYVLKQIDQSADFNIVKVEAKERKRNPQQPFTTSTMQQTANTQLNFRTRKTMMAAQQLYEGVNLGRGIGQIGLITYMRTDSTRISSLARNAAALYIHDTWGEAYSQHKPIQGKLPEGAQDAHEAVRPTDVTRTPESIKDKLTPDQFKLYSLIWSRFVASQMTPEILDTMAVTIEQNNVVFRANGSKTKFQGFTKAYPAAKEKDNALPDLSVGDKVKLTNTNPEQHFTLPPARYSEAALIKALEENGVGRPSTYAPTLDTIQRRNYVRIDARKFVPTELGEIVQTIVEESFPDITDTHFTASIEHELDEVEVGDKHWVPVIDSFYKPFSKEVEQAAATLEKVIMHDELAGMNCETCGAPMIVKMGRYGKFYACARFPDCRNTQTIIKEIGLLCPKCHKGQIVERKTKRQRTFYGCSRYPDCEFVSWDKPTEKTLADGTTPKVPEDEVSKA
(920) DNA topoisomerase I-like [Leuconostoc gasicomitatum LMG 18811]
3
MTNYLILTEKPSAAANFTKALGGKTGVFNDFTYKIANLRGHVMTLKDPEAMVAEELKKQYKSWLVKHLPWNLSDFSWARTYIRQRNMRTGKVESTKKLIDDLKKESKSGYDAIVIATDTDPSGEGELLAWEALDAIGWRGQVLRANFMDESVSGIQKAMHQLRDVSDKMADGEYVKGESRNRWDFASMQLTRIATTAAKKAGFKVVAREGRLKSVIIWRVYQQLDAIKNYVKTPYFEVKFKDPAEHVFGRVTPQGDVIPWRFATKEEAEIDFSQYHKTDVINEKHQTRTQAPGKLLDLAGLASILAPRGFSSKEVLSTYQKMYEAQIVSYPRTEDKTVTPEQFNELLPLIDQIADVVGVDKMLLTHRSPRTTHVKSQGAHGANRPGENLPKTTQSLVKFGASGPAIYEVLAKNYLAMLAEDYVYDHVTANLKDYPEFKTAFNRPLKMNFKLVYDSQKAIKVEEEEEENSTASQLGPQARPYLHEGANPKPQTPTTKWIMAFLEKHNVGTGATRVSTLSEMSRGIKAMLTETRGKLGLTETGQVSAIMVKDTWIASPKITKRLFEMMDQVGQFDMTMDQVLDSVTKVVEHDMPIMLDNAEQLETLLGKPKQVPKKKVTEKMTGLFKGEEITFAREWSGHIFTDDELTKMLNGAEISFQSKSKRGKIYTATGKLAKQTFKGSTFYGFKLNPKAKK
(592) Dna topoisomerase i (Omega-protein) [Leuconostoc kimchii IMSNU 11154]
3
MPNYLILTEKPSAAANFVKALGGKTGTFNNFTYKITNLRGHVMTLKDPEEMVAEDLKKQYKSWLVKHLPWDLNDFSWERTYIRQRNMRTGKTESTKKIIDELKKEAKTGYDAIVIATDTDPSGEGELLAWEALDAIKWRGQVLRANFMDESATGVKTAMMNLRDVSDKQQDGEYIKGESRNRWDFASMQLTRIATTAAKKQGFKVVAREGRLKSVIVWQIYAQLLAIKNYVKKPYFEVKFKDPAGHIFGRVTPDGDVIPWRFSTKNDAQKDMTQYHESAVANEKHQTRTQAPGKLLDLAGLAAILAPRGFSAKEVLSTYQKMYEAQVVSYPRTEDKTVTPEQFNELLPKIDQIAQLVQVDTRLLTHRQPRPTHVKKQGAHGANRPGENIPTSLTSLTKFGPSAQAIYDILAKNYLAMLAEDYVYDHVTADLQDYPRFKTAFNIPIEMNFKAVYDSQRAVKVEDEVEDDNSGQLGPNAQPYLYEGANKKPQTPTTKWIMAFLEKHHVGTGATRVSTLSDMSRGTKSMIKETRGKLMLTETGNVSAVMVKDTWIASPKITKRLFEMMDQVGQFEITMPKLLDSITQVVEHDMPIMLSNADELELLLGKPKPALKRPVTEKITGVFKGEEITFAKSWSGHSFTDDELTKLLNGDEISFDAKSKRGKSYTAIGKMAKQTFKGRTFYGFKLNPK
(529) DNA topoisomerase 1 [Leuconostoc kimchii IMSNU 11154]
1
MVEPGKVAKKPAAKKTTKRKKSKNQKKLVVVESPAKAKTIEKYLGSTYKVVASLGHIRDLPKSTLGVDVDNDYDPKYINIRGKGDLIKGLRKEAKAAKVVYLASDPDREGEAISWHLQHILGLDPDQPNRVVFNEITKDAIKNAFKTPRKINQDLVDAQQARRILDRLVGYSISPILWKTVKRGLSAGRVQSVALGLIIAREREIQAFEPEEYWSLDSEFQKSRQKFKATFYGFDAKKQVLPDNDSVQSVLKNIDQSADFDVMKVNAKERKRNPQPAFTTATMQQTANTQLNFRTRKTMMAAQQLYEGINLGRGIGQIGLITYMRTDSTRISSVARHAAAVYIHDTWGEEYSQHKLVQGKLPEGAQDAHEAIRPSDVTITPSSIKDKLTPDQFKLYSLIWSRFVASQMTPEILDTMAVTIEQNGVIFRANGSKTKFQGFTKAYPAAKEKDNALPDLAEGDRVKLANINPEQHFTLPPARYSEAALIKALEENGVGRPSTYAPTLDTIQRRNYVRIDARKFVPTELGEIVQTIVENSFPDVTNMKFTARVEHELDEIETGDKQWVPVIDSFFKPFSKELEIAETTLEKVVMHDELAGMDCDICGAPMLVKMGRYGKFHACSRFPDCRHTQTIVKEIGLICPKCGKGQIIERKTKRQRTFYGCSRYPDCDFVSWEKPTEKTLPDGTTPKDDEMSDGQQNSQQPTDNKEEAT
(995) DNA topoisomerase 1 [Lactobacillus plantarum WCFS1]
1
MAASTTKAKPAAKRKTATKTATKRKSKTPAKKLVIVESPSKAKTIEKYLGRSYKVVASLGHIRDLPKSKMGVDVDNDYEPHYISIRGKGDVIKGLRKEAKKAKAVYLASDPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDTVKNAFKEPRSIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSIALDLIIQRENEIKAFKPQEYWTIDSEFQKGRSKFMASFYGTHGKKQPLDDNDAVQKILGQLDRNGDFNVVKVVKKERKRFPAPPFTTSTMQQDANRKLNFRTRKTMMAAQQLYEGINVGGKEGSVGLITYMRTDSTRISSIAKHEASQFLHKEYGAEYAATKPVKGKLPEGAQDAHEAIRPSSVFRTPASIKDYLTKDQFRLYQLIWSRFVASQMTPEVLDTMAVTIDQNDVQFRANGSKTKFAGFTKIYDKTEKNNVLPDLSEGDVVKLSKTDPQQHFTQPPARYSEANLIKALEENGVGRPSTYAPTLDTIQRRYYVKLEARRFVPTELGEIVNDIIQEYFPDVVNVGFTASLEEQLDATEEGKENWVKVVDSFYKPFSKEVATAEESMEKIQIKDELAGFNCDICGAPMVVKMGRYGKFFACSRFPDCRNTKPIVKEIGVVCPQCKKGQVIERKSKKNRIFYGCSRFPDCDFVSWDKPVGRDCPKDGHYLVEKKVKGGKQVLCPNGDYTENVQK
(1615) DNA topoisomerase 1 [Lactobacillus rhamnosus ATCC 8530]
1
MADKKLVIVESPAKAKTIEKYLGRTYKVVASLGHIRDLPKSQMGVDVENNYEPKYISIRGKGDVIKSLKKDAKKASRVYLAADPDREGEAIAWHVSHILGLDPNAKNRVVFNEITKDAVKNAFKTPRGIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKNFIPEEYWSLDAEFQKGRSKKFSASFYGIKNKKMALKNNEAVQKVLSQIDKAKPFSVTNVVKKERKRFPAPPFTTSTLQQEANRKLGFRTRKTMMLAQQLYEGINLGGKLGTVGLITYMRTDSTRVSNVAKTETSHYLHEKYGEAYAAVKIRQGKLQEGAQDAHEAIRPTSTLRTPESLASVLDKDQMKLYRLIWSRFVASEMTPAIIDTVAVTLNQNDVTFRANGSQMKFEGFTKLYVSSRDSGEKDNVLPPLAVGDAVKMLKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYAPTIETIQKRYYVKLNARRFEPTELGEIVNSLIVEFFPDIVNIKFTANVESELDSIETGEANWVKVIDQFYKPFEKEVAHAETGIEKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKAIVKEIGVICPKCHKGQVVERKSKRNRVFYGCSRYPDCDFVSWDKPVGRDCPVCGHFLVEKKSKAGTQVVCPNNDYKEALQKA
(361) DNA topoisomerase 1 [Lactobacillus crispatus ST1]
1
MPTKAKSKTTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDDYKPKYISIRGKGDTIKELKSEAKKAKDVYLASDPDREGEAIAWHVAHALNLDEKAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWSIDAEFAKGKETFKSAFYGVDGKKKELPNIDSVKDVLAKIDKKKDFVVDKVVARQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKLKFAGFTKVYDNQQEKNVDLPDLEEGDKVKMTKSDNKQHFTLPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLDGRSIVPTELGEIVDGLIESFFPDITDVDYTARLENELDEVEDGKKDWVHVVDEYYQPFKKELNKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIIKEIGVVCPKCGKGQVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVILCPNGDYREDSENEKNN
(521) DNA topoisomerase 1 [Streptococcus parauberis KCTC 11537]
1
MVTKTTSKAKTTSKKATSKKKTTSPKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPEYINIRGKGPLINSLKKEAKNAKQVFLASDPDREGEAISWHLSHILGLNLEDKNRVVFNEITKDAVKNAFIEPRQVDMNLVDSQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWTIDSLFKKGTKKFQASFYGVDGKKVKLNTNEEVKDVLSRIKNDDFTVEKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMIAQNLYEGINLGSQGTQGLITYMRTDSTRISPSVQNEAATFISNRFGSKYSKHGSRIKNASGAQDAHEAIRPSNVNHTPESIAKHLNKDQLKLYTLIWNRFVASQMTAAIFDTVKVTLEQNKVTFVANGSQIKFDGYMAVYNDSDKNKMLPEMTESETVKRESSSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYYVKLAAKRFEPTELGEIVNKLIVEFFPNIVDVAFTASMEAELDQVEEGQVKWQTVIDHFYKPFSNDLVKAEDEIEKIQIKDEPAGFDCDLCGHPMVIKLGRFGKFYACSNFPDCRNTKAITKEIGVTCPICQKGQVIERKTKRNRIFYGCDRYPECDFTSWDIPVGRTCPKSGDYLVEKKIRGGGKQVVCSSETCDYKEEKVK
(178) DNA topoisomerase 1 [Streptococcus macedonicus ACA-DC 198]
1
MATTTTTKAQTAVKKSSKKTTKKKTAAKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLINNLKKEAKKSKKVYLASDPDREGEAISWHLAHILDLDENDKNRVVFNEITKDAVKNAFIEPRQIDMNLVDAQQARRVLDRIVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWTIDGFFKKGTKKFQASFYGIDGKKLKLETNEDVQKVLALLTSDEFTVAKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGKSGTQGLITYMRTDSTRISPIAQNDAANFITERFGEKYSKHGSRVKNASGAQDAHEAIRPSNVNLTPESIAKHLDKDQLKLYTLIWNRFVASQMTAAVFDTMKVNLEQNNVRFTANGSQVKFDGYLAVYNDSDKNKMLPNMVEGDIVKKVSTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLDVIQRRYYVRLAAKRFEPTELGEIVNNLIVEFFPDIVDVKFTADMEGKLDEVEEGKQQWQKVIDEFYKTFEKELAKAETEIEKIQIKDEPAGFDCDLCGHPMVIKLGRYGKFYACSNFPECHNTKAITKEIGVTCPVCGKGQVIERKTKRNRIFYGCDRYPECEFTSWDKPVGRSCPKSGDFLVEKKIRGGGKQVVCSNEECDYEEAKIK
(1394) DNA topoisomerase [Streptococcus macedonicus ACA-DC 198]
3
MKYLLLAEKPDQAKKYANALGNPKNDKGVWRVQSSVLNAEVIVAPAVGHLVERINPYTNFENWEMANLPALPEGFSYEPKKDTIKRFKAIKKAVKEVDAIIIGTDPDREGEAIAYRILELIPGALRKIKYRLWANSLTKKGLEQAFSSLKNPKDSVNYFHEADARGDADWLVGFNLSPFVTIKMKEEGYLDKKDHSMSVGRVQTPIVSLIVRNDEAIENFKPSPYWQLKLIDPEAKVTFGNDIKYQSKAEAEQMLQQLANIAVVKTVTSEEKVQEAPKLYNLTNFQSEMSKLYHFDATKTKELVQSLYQKGYLSYPRTDSTLITTNEFAYLVEHIEDYQKAINKQLETPNRSPRKAYVNDKKVLEHYAIIPTETIPDLSELSDDEKLIYQKVVFRTLLMFTPDYRYQSTSVILDNHGLEFKATGAVTKDKGWRNYLAVKKEDKELPNYQEGQTITVECKLLEEMTKPPTRITEQILLKKLLPKYNLGTSATRDGMIDLIQDKGYVTKNKKTGQFFPTERGKLLIHYLDQLEIAYTNPETTGKWEEVLAQIGQGKIQKEAFVDKIKWAITKQIEKGKQI
(889) DNA topoisomerase 1 [Streptococcus pyogenes str. Manfredo]
1
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENKIKAFVPEEYWSIDGLFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVSNGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
(1432) DNA topoisomerase 1 [Streptococcus equi subsp. zooepidemicus ATCC 35246]
1
MCQLVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKYLGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINSLKKEAKNAKKVYLASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPKEYWSIDGLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSQLSSDDFMVSKVEKKERRRHAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVAQNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKSKMLPEMAEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRYYVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQFYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHHTKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGDYLVEKKIRGGKQVVCSNEACDYKEEIVK
(1493) DNA topoisomerase 1 [Lactococcus lactis subsp. lactis IO-1]
1
MPTSTKSKTKKTTKKKTTRKRVTPGKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSTMSVDIENDYEPQYINIRGKAPLINSLKKEAKAAKAVYLASDPDREGEAISWHLAHILNLPLEEKNRVVFNEITKDAVKNAFKEPRQIDVDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIVDRENEINAFIPEEYWSIDGEFKKGTKKFKASFWGIDGKKHPLKTNEDVIKVMERLDGPDFNVDKVEKKERRRNAPLPYTTSSMQQDAANKLNFRTRKTMMVAQQLYEGLTLGSQGHQGLITYMRTDSTRISPVAQSAAHNYIADQFGEKYSKHGSKVKNASGAQDAHEAIRPSNVFNTPDAIAKYLDKDQLKLYTLIWNRFVASQMVAAIFDTVKVNLSQNGVIFIANGSQVKFDGYLRIYNDSDKSNMLPEMEENETVKKANVKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLETIQKRYYVRLSAKRFEPTELGEIVNKLIVEFFPNIVNTEFTAEMEKDLDEVEEGKRQWIEVVDQFYKPFAKELENAEEGMEKIQIKDEPAGFDCDVCGSPMVIKLGRFGKFYACSNFPDCRNTKAIVKEIGVKCPLCHEGNIIERKTKKNRIFYGCDRYPECEFTSWDKPIGRDCPKSGHFLVEKKVRGGGKQVVCSNDECDYQEEKQK
(1845) DNA topoisomerase [Lactobacillus sakei subsp. sakei 23K]
7
MRKKLVITEKPSVAKELAKVLGTNQKTKTYFEGDQYVITWAFGHLLSLQLPEDIKKEWQQWRLEDLPIIPKHIGLKPLPKTGGQLKAISHLAHRQDISGAVIATDSGREGEAVARYILEWIKFDKPVERLWISSQTTKAIKDGFANLKPAKQFDNLYASALARGHADWLIGLNVTRALTTKYEDNLSAGRVQTPTLAFVNETAQQISRFKPEKYYTIQLKVGQEQATLQMAKPQGLKDRAQAETLVAKLKQAQGKVGSVKTSQKSQAAPLPYDLTELQQVANAMYGLSAKKTLSLIQSLYEIHKVVSYPRTDSKYLSTDIEGTLKERLSALVKFDPRAKQYLGQGAKVKQPAVFNDRKVTDHYALIPTEEPVRAEKLSTDELRMYRLIVERFMGLFADQYVTAVTKATVQFGDHTFTFKQTKVVQQGWHADSKETPTTSVDWQEGAVVPADFSIKEQLTSAPKPLTEGTLLGKMEHYGLGTPATRAEIIEKLVRSELLERRGHSLAVTPKGQQLLKLVNKTLVSPELTGKWENSLEAIARGQENQKAFITEIEAATKTLVSEIKKSETEYHDFAITNKKCPECDHPLKERNTRDGKVYVCTNCHYRRRKDPKVSNHRCPQCHKKMVIIEGQAGAYFRCLNDGTTEKMLDKKDCKKKISKHEERRLIQKVNQEEEPAESPLAAALRKAMEK
(1150) DNA topoisomerase 1 [Lactobacillus sakei subsp. sakei 23K]
1
MAGKNLVIVESPAKAKTIEKYLGRNYKVVASKGHIRDLPKSQMGVDFENNYEPKYISIRGKGETIKELKKHAKKADHIYLAADPDREGEAIAWHVSHILKLDPTDKNRVVFNEITKDTVKSAFKNPRSIDMKLVDAQQARRVLDRIVGYSISPLLWQKVKKGLSAGRVQSVALKLVIDREQEIKAFKPEEYWSLDAEFKKGRSKFKASFYGLNGKKTALGNNDAVQDVLKQIDKTQPFTIEDVKKRERKRFAAAPFTTSSLQQEANRKLNFRTRKTMMQAQQLYEGINLGGKEGTVGLITYMRTDSTRISTGAKHEASQFIHDNYGEEYAAVKAHKTKNPEGAQDAHEAIRPTSVMRTPKSLKDVLTNDQYKIYNLIWSRFVASQMTPAVFDTVAVKINQNNVLFKANGSQMRFPGFTKLYVSSRDTEDSAKDNLLPELAVGDEVKLAKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYSPTIETIQRRYYVKLNAKRFEPTELGEIVNNLIVEFFPDIVSIDFTADLEHRLDEVETGQENWIKIIDNFYQPFEKEVEKASVQIEKVQIKDEPAGFDCDICGAPMVVKMGRYGKFFACSRFPDCRNTKAIVKEIGVTCPKCGKGQVIERKSKKNRLFYGCDRYPDCDFVTWDKPVGRNCPKCEHYLVEKKIKGGKQVICPNGDYEEAVQK
(486) DNA topoisomerase 1 [Lactobacillus casei ATCC 334]
1
MADKKLVIVESPAKAKTIEKYLGRTYKVVASLGHIRDLPKSQMGVDVDNDYEPKYISIRGKGDVIKSLKKDAKKASKIYLAADPDREGEAIAWHVSHILGLDPKAKNRVVFNEITKDAVKNAFKTPRGIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKNFTPEEYWSLDAEFQKGRSKKFSASFYGLKNKKQALKNNEAVQKILGQVDKTKPFAVTNVVKKERKRFPSPPFTTSTLQQEANRKLGFRTRKTMMLAQQLYEGINLGGKLGTVGLITYMRTDSTRVSNVAKTETSHYLHEKYGEAYAAVKIRQGKLQEGAQDAHEAIRPTSTLRTPDSLTAVLDKDQMKLYRLIWSRFVASEMTPAIIDTVAVTLDQNGVTFRANGSQTKFEGFTKLYVSSRDSDQKDNILPPLAVGDDVKMLKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYAPTIETIQKRYYVKLNARRFEPTELGEIVNSLIVEFFPDIVNVKFTANVESELDRIETGEADWVKVIDQFYKPFEKEVAHAETGIAKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPNCRNTKAIVKEIGVVCPKCHIGQVVERKSKRNRVFYGCSRYPDCDFVSWDKPVGRDCPVCGHFLVEKKSKAGTQVVCPNNDYKEALQKA
(1100) DNA topoisomerase 1 [Lactobacillus ruminis ATCC 27782]
1
MESPSKAKTIEKYLGNRYKVMASLGHIRDLPKSKMGIDVENNYEPHYISIRGKGDVIKELRKEAKKADHVYLAADPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDAVKNAFKTPRAIDMNLVDAQQARRALDRLVGYSISPLLWSKIKKGLSAGRVQSIALNLIIKREKEIRNFKPEEYWTIDAEFKKGRSKFEGSFYGIDGKKTALQNNDAVKSVMERIDTKKPFTVDNVEKKERKRQPPLPFTTSTMQQVANNNLKFRTQKTMMVAQQLYEGINIGRSGTVGLITYMRTDSTRISEVAKHEASEFIHSEYGENYAAIKPRQGKLAEGAQDAHEAIRPSSVLRTPKSLEKYLDKDQMKLYSLIWSRFVASQMTPAVIDTMRVDLEQNGVSYRSTGSKLKFDGFTKVYADSKHKDNMLPDLENGDEVIMSRNQPNQHFTLPPARFTEAALIKTLEENGVGRPSTYAPTLNTIQKRYYVKLAARKFEPTELGEIVDNMIGKCFPDILNVKFTAKLEDQLDEIEEGKQEWVKVVDEFYKPFSTEVKTAEEKMAKVKIKDEPAGFDCEICGAPMVVKMGRFGKFYACSRFPDCRNTKAIVKQIGVKCPQCKRGEIIERKSKKNRLFYGCNRYPECDFISWDKPIARDCPKCGHFLIEKKTKQGMQVKCPNNDYEEAIQK
(242) DNA topoisomerase [Lactobacillus ruminis ATCC 27782]
7
MKQLILAEKPSVARDLSQILGATEKHKDYFEGDGVIVTWALGHLLGLKMPEDLNKDWQKWQLETLPMLPKFIGTKPLPKTRHQLQAIERLAKRSDVKEAVIATDAGREGELVARWILQYVRFNKPVKRLWISSQTTKAVKEGFARLKPASDYDDLYQSALARATADWLVGLNVTRALTVKYQDNLSAGRVQTPTLALVLKQEDKISSFIPQKYYQIALNASNQKALMEQKNPYGIKNREAAQKIVSELERTIGKVEKITVKEHSEKAPLPYDLTELQRAANEKYGYSAKKTLSVVQSLYEVHKIVSYPRTDSKYLSTDMISTMKERLQAVGSMVPEALEYAKKGAKVVQKKVFNNEKVTDHHALVPTEQRPDYAKLSSDEHRIYGMIVKRFVMLFAPEYREQKEKITVSFANRRFNFSKTTVLQKGWKENAQTSGEALHFKEGQQIKGTFEVKEKLTTPPNPLTEGGLLALMERYSLGTPATRAEIIEKLVSSELMERSGNFLRVTRKGRQLLELVNPSLVTPELTEKWEKQLEAIALGKFSSQKFIAEIKDDTKKLVSEVKNSTKKYQDFSMTQKKCPECGAFLKEKKVRDGKLLVCSNAECDYKRRAEARVSNHRCPQCHKKMLIVSGEKGEYFRCKYDGTTEKLGGKKGKKKMSRHEERRLLKKINQDDEPQESALAAALKKAMEEK
(77) DNA topoisomerase 1 [Aerococcus urinae ACS-120-V-Col10a]
1
MATKRKKTPKKDLVIVESPTKAKTIEKYLGRKYKVVASKGHLRDLPKSKMGIDIENNYDPHYITIRGKGDTIKDLKKEAKKANNIYLASDPDREGEAIAWHLAHILKLDPKEDIRVTYNEITKDTVKEAINNPRAIDKDLVDAQQARRILDRLVGYNLSPILWAKVKKGLSAGRVQSVALKMVVDREDEIRNFVPEEYWSIEGVFQKGKETFKANASKYKGKKIDLKNEDDVKALMANLSSDQFEVQNLTKKQRKRNPQKPFTTSSLQQEASKRLRFRTRKTMMVAQQLYEGIKLGSEGTVGLITYMRTDSTRISEGAKQEAGQFIQEKYGKEYIGKGTSGASGQGAQDAHEAIRPTSAFRHPDSVEAYLSKDQFKLYSLIWSRFMASEMAPAVYDTVACDLVQNDVSFRANGSKIKFTGYLRVYPDNNEKDNLLPELENGEKVKSKELTPNQHFTQPPARYTEASLIKTLEELGVGRPSTYSPTLETLIKRYYVKLEARRFEPTELGEIVNSLISEFFPDIVDPQFTANLEDELDHVEDGNKNWIDVVDAFYQPFSKDIEKADQEMEKIEIKDEPAGFDCDVCGHPMVIKLGRYGKFYACSNFPDCRNTKAIVKEIGVNCPTCKEGQVVERKSKKKRIFYGCSRYPDCDFVSWDKPVGRSCPKCDHYLVEKKKRGSKQVICSNCDYKEDVQKGDD
(850) Topoisomerase IA [Leuconostoc citreum KM20]
3
MPNYLILTEKPSAAANFVKALGGKNGQFDTFTYTITNLRGHVMTLKDPEEMVSEDLKKQYKSWLIKHLPWNLNDFNWARTYIRQRNLRTGKVASTKQLVDDLKKEAANGYDAIVIATDTDPSGEGELLAWEALEAIKWRGQVLRANFMDESVKGIQTSMQHLRDVSDKNQDGEYIKGESRNRWDFASMQLTRIATTAAKKQGFKVVAREGRLKSVIVWQIYAQLEAIKRYVKKPYFEVKFKDLAGHIFGRITPEGDVIPWRFDSKAVAQQDLLQYHESAVTNERYQTRTQAPGKLLDLAGLAAILAPRGFSAKEVLSTYQKMYEAQVVSYPRTEDKTVTPEQFNELLPKIDQIAQVVHVDTALLTHRQPRATHVKNQGAHGANRPGENVPTDLATLTKFGASAQAIYEVLAKNYLAMLAEDYVYDHVTANLTDYPIFKTAYNVPVQLNFKAVYDSQRAIKVDDDDETAVMGQLGPTAQPYLYEGANKKPQAPSTKWIMAFLEKHNVGTGATRVSTLSDMSRGTKAMIKETRGKLTLTETGNVSAVMVKGTWIASPKITKRLFEMMDQVGRFEMTMPKLLDSVTQVVVHDMPIMVANAEQLETLLGQPKIKPKRPVSEKTTGQFKGEEITFAKEWSGHVFTDEELTKLLNGAEISFEAKSKRGKLYTATGTMAKQTYKGRTFYGFKLKPKPKK
(141) DNA topoisomerase 1 [Leuconostoc citreum KM20]
1
MAESEKKKTTTTKKTKKTTTKTRKKNLVIVESPSKAKTIEKYLGSTYKVIASLGHVRDLPKSTLGVDVDNNYEPKYINIRGKGDIIKGLRQAAKAAKNVYLASDPDREGEAIAWHLQHILQLDDTAPNRVVFNEITKDTVKNAFKTPRLINQDLVDAQQARRILDRLVGYSISPILWKTVKRGLSAGRVQSVALGLIIKREKEIQSFEPEEYWTLDAVFKKGRSKIQSVFYGVDDKKQQLPDNDSVQDVLRRLNRNEPFEIGKVEAKERKRNPQRPFTTSTLQQTANTQLNFRTRKTMMAAQQLYEGINLGRGIGQTGLITYMRTDSTRISEMARHAATQYIHETWGEEYAQHRLVKQPSAEGIQDAHEAVRPTDVTRTPDSIKDKLTPDQFKLYSLIWSRFVASQMTPEILDTMAVTITQNGVLFRANGSKTKFPGFTKAYPAAKEKDNTLPHLEEGDQVKIEQTDPEQHFTQPPARYSEAALIKALEENGVGRPSTYAPTLETIQKRNYVRLDARKFVPTELGEIVQTIVEESFPDVTNTQFTARIEHELDEVEVGAKYWVPVIDEFFKPFSKEVEKAETTLEKIIMHDELAGIDCSVCGAPMLVKMGRYGKFYACARFPDCRHTETIVKEIGLLCPKCHKGQIVERKTKKQRTFYGCSRYPDCDFVSWEKPTDKTLPDGTTPKENSKNQAKTTD
(578) DNA topoisomerase 1 [Lactobacillus brevis ATCC 367]
1
MPTKAKPKAKTKTRRKPQKKLVIVESPAKAKTIEKYLGRTYKVVPSLGHVRDLPKSSMGVDTENDYDPHYISIRGKGDVIKGLRSEAKKAKAVYLASDPDREGESIAWHLAHVLNLDVTDKNRVTFNEITKDAVKEAFKTPRSIDMNLVNAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSIALSLIIQREKEIKAFIPEEYWTIDGEFKKARHTFAASFYGLNGKKTGLKDNDAVQAVLSKLDKKGNFDITNVVRKERKRTPQPPFTTSSMQQDANRKLNFRTRKTMMAAQQLYEGINLGKEGTQGLITYMRTDSTRISNIAKHEASTFIHEKYGAEYAATKPIKGKLPEGAQDAHEAIRPTSVFRTPASLKERLTKDQFRLYQLIWNRFVASQMTNAIMDTMAVTLEQNGVTFRANGSKMKFEGFLKIYKDGKEKDNLLPDLEIGDQVKLAKTDPAQHFTQPPARYSEANLIKALEENGVGRPSTYAPTLDTIQRRYYVKLVGRRFEPTELGEIVDGIINDYFPDVVNVDFTADLEHELDGIEDGKQDWVKVIDSFYKPFSTEVAHAEDAIEKIQIRDEPAGFDCDIYGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVTCPVCHKGEVIERKSKKNRIFYGCSRYPDCDFVSWDKPVGRDCPKDGHYLVAKKIRGGSQIVCPNGDYEEAPQK
(466) DNA topoisomerase 1 [Lactobacillus fermentum IFO 3956]
1
MSLATKQESTTKKKTTRRKVSRTNQKKLVIVESPSKAKTIGKYLGRTYKVVASLGHVRDLPKSRMGVDIDHDYQPDYISIRGKGDVIKELRKDAKAAKAVYLASDPDREGEAIAWHVANLLKMDPTEKNRVTFHEITKDAVKEAFKEPRTINMNLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSVALNLIIQRENEIRNFVPEEYWTIDADFKKGREKFQASFYGQNGKKANLKNQEAVQAVLQQLDRQQDFSITKVDRRERRRMPQPPFTTSTMQQDANRRLNFRTRKTMMAAQQLYEGINIGQGAAVGLITYMRTDSTRIAGVAKHEASTFIHEHYGAEYAATKPVKGKLQEGAQDAHEAIRPTSVNRTPAEMKEFLTPDQYKLYNLIWSRFVASQMTPQVTDTMAVTITQNGVDFRANGSKVKFDGFTKVYKGSQGKDNILPNLEEGDAVKMVADNPAQHFTQPPARFTEAALVKTLEENGVGRPSTYAPTLDTIQRRYYVKLESRHFEPTELGEIVNDLITKQFPDIVNVKFTAEVEDSLDKIEEGKENWVQVVDGFYKPFSKEVATAEEQVAKIEMKDELAGSNCEICGAPMVIKMGKYGKFYACSRFPNCRNTKAIVKDTGVECPLCHQGTVVERKSKKNRVFYGCSRYPDCDFLSWDRPIGRDCPKDGHFLVEKKVKGGKQVLCPNGDYKEEVQK
(886) DNA topoisomerase 1 [Streptococcus agalactiae A909]
1
MATTTKTSTKKTSKKKSATAKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLINDLKKEAKKAKKVYLASDPDREGEAISWHLAHILDLDKEDRNRVVFNEITKDAVKNAFVEPRQINMDLVDAQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFQPEEYWTIDGSFKKGTRKFNATFYGLDGKKFKLSNNEDVKTVLKRIKTDEFLVEKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMIAQQLYEGLSLGTAGHQGLITYMRTDSTRISPLAQNEATEFITNRFGANYSKHGNKVKNASGAQDAHEAIRPSSVNHTPESIAKYLDKDQLKLYTLIWNRFIASQMTAAVFDTMKVNLTQNGVTFIANGSQVKFDGYMAVYNDTDKNKMLPDMEEGESVKKVNTNPEQHFTQPPARFSEASLIKTLEENGVGRPSTYAPTLETIQKRYYVKLAAKRFEPTELGEIVNSLIVEFFPDIVDVTFTAEMEGKLDEVEIGKEQWQKIIDEFYKPFEKELAKAETEMEKIQIKDEPAGFDCELCGSPMVIKLGRYGKFYACSNFPECHNTKAITKEIGVICPICQKGQVIERKTKRNRIFYGCDRYPECEFTSWDKPIGRTCPKSNDFLVEKKVRGGGKQVVCSNEKCDYQEEKIK
(134) DNA topoisomerase 1 [Streptococcus uberis 0140J]
1
MVTKTKSVAKTAKKKATKKKSTSPQKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPEYINIRGKGPLINSLKKEAKNAKKVFLASDPDREGEAISWHLSHILGLESDDKNRVVFNEITKDAVKNAFLEPRVIDMDLVDAQQARRVLDRIVGYSISPILWQKVKKGLSAGRVQSVALKLIIDRENEIKAFVPEEYWTIDGLFKKGRQKFQASFYGLNGKKMKLETNDDVKFVLSHLKSDAFDVTTVEKKERRRNAPMPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGINLGSNGTQGLITYMRTDSTRISPIAQNEAAAFITERFGSNYSKHGNKVKNTNGAQDAHEAIRPSNVHYTPESIAKYLNKDQLKLYTLIWNRFVASQMTAAIFDTVKVTLEQNSVSFIANGSQIKFNGYMAVYNDSDKNKMLPEMTQGEVVTKESTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVNVTFTAEMEAKLDQVETGERQWQTVIDTFYKPFAKDLEKAEDEIEKIQIKDEPAGFDCDLCGHPMVIKLGRFGKFYACSNFPDCRNTKAITKEIGVTCPICKKGQVIERKTKKNRVFYGCDRYPECEFTSWDIPVGRECPKSGDYLVEKKIRGGGKQVVCSSESCDYKEEKIK
(1728) DNA topoisomerase [Oenococcus oeni PSU-1]
7
MTTVILAEKPSQARSYVEALKNSTKKEGYFSVSDPVLANETFITYGFGHLVELATPEKYDQKYKRWSLSNLPIFPDKYKFIVPRDKKTQFKIVKDLLMKADTIIIATDSDREGENIAWSIMNQAKINLKSKTIKRLWINSLEKDAILNGFKNLKDAWNYYPAYQEAQTRQISDWLVGMNGSPLYTLLLRQSGVRGVYSIGRVQTPTLYMVYQRDQEIKNFKPEPYFEISAEIEANRQKFVAKLDPYQRFKDEESLTIYMEAKGLRTGFQEALTKDVLQETKRTASPRLFSLSSLQSAINKRYHASASDVLKAVQALYEAKLLTYPRTDCNYITDQEFSYLLSNLMGYLSLVSSQVSLNNTEANKRYVNSKKVQEHHAIIMTKTIPNKAKLAALPKLQQQVYGLVLRTTLAMFADPYEYEQTIIITEVGKANFKATGNVPIKQGWKLLFADDKDKNDETVVTLPKVTKNQKVQADLKTPQKETTPPVPFTEGTLITAMKTAGRTLDDEEAQSILKDVEGIGTEATRANVLEVLKKRGYLLSKKNQLHVSEQGITLCTAVELEPLLTSPEMTAKWELALKEISQKKRSQESFLIQIKKFVSKLVDEVPTQMKQSEGLSKQVKNQKIVEIQDRQQEAIGRCPLCKEGMIVDKGKFYGCTNYKAAVPCRFTLPKKWSEKTIGKTAIKALITKGESNRLKGFKSKKSGKKFDAKLKLEGSKLSFDFS
(3) DNA topoisomerase 1 [Oenococcus oeni PSU-1]
1
MVTKKKKAKKLVIVESPAKARTIENYLGRDYEVLASMGHIRDLPKSQLGVDTEHNYEPKYINIRGKAPLINSLKKAAKSASAVYVASDPDREGEAIAWHLGHILGLPDGGKNRVTFNEITKPAVKEAFKHPRGIEQDLVDAQQARRVLDRLVGYSISPILWQKVKRGLSAGRVQSVALGLILDKEKEIAAFVPKEYWSLNANFKAGKHEFSAEFYGTDGKKVKLDNQKSVSKILKRIDSSKDFKITDISTKESKRNAPNPFTTSSLQQTANSQLNYHARKTMQIAQGLYEGISLPKIGHVGLITYMRTDSTRLSETAQEMAKKFIVDKFGKEYYHRHNVVKKSENVQDAHEAIRPTDAERTPESLKEILTRDQYRLYNLIWSRFIASQMSEQKLENQSLMIEQNKTVWRATGIKVLFEGWTMALKTSSTKNNILPALKIGDLVQMVNNLPEQHFTQPPARYTEASLIKALEELGVGRPSTYAPTMDTIQRRGYIGFDQKKIVPTDLGDIVQDVVVKSFPEVTDKQFTSKIEDELDKVETGNVKWQKVIDEFYKPFSKEVDAAIENLEKVPIYDRIAPELCDICGSLMVIRRSRRGEFYACSRFPDCHGTKSIVEEIGMKCPKCGIGEVVIKRTKRGRIFYGCSRYPDCDFASWTKPKKNEETEENNETK
(1308) DNA topoisomerase 1 [Streptococcus gallolyticus UCN34]
1
MATTTTTKAPTAVKKSSKKTTKKKTAAKKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSSMSIDFENNYEPQYINIRGKGPLINDLKKEAKKSKKVYLASDPDREGEAISWHLAHILDLDENDKNRVVFNEITKDAVKNAFVEPRQIDMDLVDAQQARRVLDRIVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKAFKPEEYWTIDGFFKKGTKKFQASFYGIDGKKLKLETNEDVQKVLALLTSDEFTVAKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGKSGTQGLITYMRTDSTRISPIAQNDAANFITERFGEKYSKHGSRVKNASGAQDAHEAIRPSNVNLTPESIAKHLDKDQLKLYTLIWNRFVASQMTAAVFDTMKVNLELNSVRFTANGSQVKFDGYLAVYNDSDKNKMLPDMVEGDIVKKVSTNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLDVIQRRYYVRLAAKRFEPTELGEIVNNLIVEFFPDIVDVKFTADMEGKLDEVEEGKQQWQKVIDEFYKPFEKELAKAETEIEKIQIKDEPAGFDCDLCGHPMVIKLGRYGKFYACSNFPECHNTKAITKEIGVTCPVCGKGQVIERKTKRNRIFYGCDRYPECEFTSWDKPVGRSCPKSGDFLVEKKIRGGGKQVVCSNEECDYEEAKIK
(784) DNA topoisomerase [Streptococcus gallolyticus UCN34]
3
MVSSLKYLLLAEKPDQAKKYATALGNPKNEKGVWRVQSSVLNAEVIVAPAVGHLVERINPYTNFENWEMTNLPALPEGFSYEPKKDTIKRFNAIKKAVKEVDAIIIGTDPDREGEAIAYRILELIPEALRKIKYRLWANSLTKRGLEQAFANLRSPTDSINYFHEADARSDADWLVGFNLSPFVTIKMKEEGYLDKKDHSMSVGRVQTPIVSLIVRNDEAIENFKPSPYWRLKLIDSEAEVIFSNDIKYQSQMEAEQVLQQLANTAVVKTVTSEEKAQEAPKLYNLTNLQSEMSKLYHFDATKTKELVQSLYQKGYLSYPRTDSTLITTNEFSYLVDHIEEYQKAINKQLETPNRSPRKNYVNDKKVLEHYAIIPTENIPDLSELSDDEKLIYQKAVFRTLLMFTPDYRYQSTSVILDNHGLEFKATGTVTKDKGWRGYFAVKKEDKELPHYQEGQEVIVDCNLLEEMTKPPTRITEQILLKKLLPKYHLGTSATRDGMIDLIQDKGYVTKHKKTGQFFPTERGKLLIHYLDQLEIAYTNPETTGKWEEVLAQIGQGKIQKEAFVNKIKWAITKQIEKGKQL
(868) DNA topoisomerase 1 [Streptococcus pseudopneumoniae IS7493]
1
MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGHIRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAISWHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTIDAIFKKGTKQFQASFYGVDGKKLKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGSKYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQMTAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNSKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTELGEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWQRVIDAFYKPFSKEVAKAEEEMEKIQIKDEAAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPSCHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQIVCSKGDYEEEKIK
(843) DNA topoisomerase 1 [Lactobacillus sanfranciscensis TMW 1.1304]
1
MVESPAKAKTISKYLGRTYTVVASKGHIRDLPKSRMGIDIPDDFKPDYISIRGKGDTIKMLKAEAKKAKEVFLASDPDREGEAIAWHVSHVLNLDVNDKNRVTFNEITKETVKDALKHPRTIDMNLVDAQQARRIIDRLVGYSISPILWKKVKKGLSAGRVQSVALWIIIKREREIQAFNPEEYWTIDSIFKKGRSKFKASFYGVDGKKFPLGNNDDVQNVLKRLDAKADFEITDVKKREKKRQPPRPFTTSTLQQDANKKLHFKTGRTMMAAQQLYEGINIGKEGSQGLITYMRTDSTRISAGAKLEAAQFIHDEYGPEYALNHPRKLKLPEGAQDAHEAVRPTSVMRTPKQIEKYLTKDQFKLYNLIWSRFVASQMTPAIVDTETIKVVQNGVEYRANGSKLNFEGYLKAYSAGKKKDNILPDLEIGDHITLDNNVPNQHFTQPPARYTEASLIKALEENGVGRPSTYAPTLMTIQKRYYVKLDARRFVPTELGEIVNKLIEEYFPEIVNVDFTADIEGKLDDIEEAKLRWVKLVSEFYQPFSKEVSYAEKEMEDVQIKEPLAGFNCNICGSPMVEKMGKYGKFFACSRFPDCRNTQTIVKEIGVICPKCHEGQVIERKTKKNRLFYGCSRYPDCDFVTWDKPIGRDCPKCGHFLVNKKVRGGWQVICPEGDYEENAIK
(910) DNA topoisomerase 1 [Lactobacillus kefiranofaciens ZW3]
1
MPTKVKSKTKTTKRNTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKDVYLASDPDREGEAIAWHVAHALNLDEKAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWTIDAEFKKEKESFKSAFYGLNGKKTELANIDAVKDVLAKIDKKKDFTVEKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQKEASQFLHENYGAEFAAKSQRHFQNQEDAQDAHEAIRPTSVYRTPASLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKMRFAGFTKVYDNQQEKNVDLPDLQEGDRVKMSKSDNKQHFTLPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLEGRSIVPTELGEIVDTLIEQFFPDIANVDYTAHLENELDEVEDGQKEWTHVVDEYYQPFKQELNKADSEIEKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVTCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKKSKKGLTVLCPNGDYREEPQEGESNK
(1669) DNA topoisomerase 1 [Pediococcus pentosaceus ATCC 25745]
1
MPAAKKNLVIVESPSKAKTIEKYLGRTYKVVASLGHIRDLPKSKMGVDLENDYEPHYISIRGKGDTIKNLRKEAKKAKKVYLASDPDREGEAIAWHLSYLLGLDPKDQNRVVFNEITKDAVKNAFKTPRSIDMTLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALSLIIKREQEIKAFEPEEYWSIDSEFKKGRSKFKAAFYGVNNKKMKLPNNDKVQEVLKKIDPKADFDITEVKRRERKRYPAPAFTTSSMQQEANKTLNFRTRKTMMAAQQLYEGINIGKEGTVGLITYMRTDSTRISEVAKHETSLFIHDEFGAEYAATKPRKGKMPEGAQDAHEAIRPSSVLRTPESIKEYLNKDQFRLYNLIWSRFVASQMTPEVSDTMTVKIEQNGVQFRANGSKTKFEGFTKVYKTNKDKDNVLPNLEEGDQVQLVTNNPNQHFTQPPARYSEATLIKALEENGVGRPSTYAPTLDTIQRRYYVKLESKHFEPTELGEIVNEIIYDFFPDIVNIDFTAGLEKDLDSIEEDKEDWVKVVDRYYKPFAKELAKAQEQIEKVQIKDELAGFNCEICGSPMVVKMGRYGKFFACSRFPDCRNTQAIVKEIGVTCPKCHQGQIIERKSKRGRLFYGCSRYPDCDFVSWDKPIARECPVCHSYLIEKKIKGGKQIVCPNGDYEETPQK
Family distribution
Taxonomy tree
Lactobacillales