Selection 1

Selection 2

Selection 3

All selections

Taxon : Thermotoga

Informations

Name	Thermotoga
Rank	genus
# topoisomerases	15

Lineage and sub-taxa

Lineage	Bacteria > Thermotogae > Thermotogae > Thermotogales > Thermotogaceae > Thermotoga
Sub-taxa

Topoisomerases

Select all	Name	Family	Sequence
	(627) Reverse gyrase [Thermotoga maritima MSB8]	6	MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLPEDSPSDIYRALLERKTLKEYRFYHEFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTTFGMMTALWLARKGKKSALVFPTVTLVKQTLERLQKLADEKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISSRSKEKLVELLEIFRDGILIFAQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGVDLPERIKYVIFWGTPSMRFSLELDKAPRFVLARVLKEMGLIKAQENPDVEELRKIAKEHLTQKEFVEKVKEMFRGVVVKDEDLELIIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEEAEANWKELVHEVEESRRRSERELTDTSRSLLIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEENGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPSTRSLRRIEMHEITRYGFKKARESVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQEAEEEKNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLRKIGKEDIFMGRSWSTEGAHEAIRPVKPIDARELEEMIEEGLIADLTKKHLRVYELIFNRFLASQSAAVKVKKQIVTVDVDGKRMGIEQIVEILRDGWNLFVPLTVSPRFEHRTYKIKEKKFYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEEG
	(91) DNA topoisomerase 1 [Thermotoga maritima MSB8]	1	MSKKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKSKFGVDLEKDFEPEFAVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGRKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKSNLSAGRVQSATLKLVCDREREILRFVPKKYHRITVNFDGLTAEIDVKEKKFFDAETLKEIQSIDELVVEEKKVSVKKFAPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERRKSNAKIQDAHEAIRPTNVFMTPEEAGKYLNSDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWKTERNTGEFPFEEGESVKPVVVKIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTIVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYESFSSVFDRNDRIVVDFPTNQKCSCGKEMRLSFGKYGFYLKCECGKTRSVKNDEIAVIDDGKIFLGRKDSESGSPDGRSVEGKGNLSEKRRKGKKGS
	(90) DNA topoisomerase 1 [Thermotoga maritima MSB8]	1	MSKKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKSKFGVDLEKDFEPEFAVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGRKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKSNLSAGRVQSATLKLVCDREREILRFVPKKYHRITVNFDGLTAEIDVKEKKFFDAETLKEIQSIDELVVEEKKVSVKKFAPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERRKSNAKIQDAHEAIRPTNVFMTPEEAGKYLNSDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWKTERNTGEFPFEEGESVKPVVVKIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTIVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYESFSSVFDRNDRIVVDFPTNQKCSCGKEMRLSFGKYGFYLKCECGKTRSVKNDEIAVIDDGKIFLGRKDSESGSPDGRSVEGKGNLSEKRRKGKKGS
	(626) Reverse gyrase [Thermotoga maritima MSB8]	6	MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLPEDSPSDIYRALLERKTLKEYRFYHEFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTTFGMMTALWLARKGKKSALVFPTVTLVKQTLERLQKLADEKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISSRSKEKLVELLEIFRDGILIFAQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGVDLPERIKYVIFWGTPSMRFSLELDKAPRFVLARVLKEMGLIKAQENPDVEELRKIAKEHLTQKEFVEKVKEMFRGVVVKDEDLELIIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEEAEANWKELVHEVEESRRRSERELTDTSRSLLIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEENGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPSTRSLRRIEMHEITRYGFKKARESVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQEAEEEKNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLRKIGKEDIFMGRSWSTEGAHEAIRPVKPIDARELEEMIEEGLIADLTKKHLRVYELIFNRFLASQSAAVKVKKQIVTVDVDGKRMGIEQIVEILRDGWNLFVPLTVSPRFEHRTYKIKEKKFYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEEG
	(1106) DNA topoisomerase 1 [Thermotoga neapolitana DSM 4359]	1	MSKKKKYIIVESPAKAKTIKGILGPEYEVFASMGHIVDLPKSKFGVDLKNDFEPQFTVIKGKEKIVEKIKAISKVGEIFIASDMDREGEAIAWHVARLTNTLGKRNRIIFSEITPRVIKEAVKNPRKIDMNKVHAQLARRILDRIVGYSLSPVLWKNFKSNLSAGRVQSATLKLVCDREREILRFVPKKYHRVVVKFHGLEAEMITKEKTFLEEDVLKELQSIEELVVEEKTVSRKKFSPPDPFKTSSLQQEAYAKLGFSVAKTMLLAQQLYEGVETKEGHIAFITYMRTDSTRVSDYAKEAARELIEKDFGKEYIGTGRRKKSRTARIQDAHEAIRPTDVFMTPEKISKYLNPDQRKLYELIWKRFFASQMKPSEYEETRFVLRSKDGKYRFKGSILKRIFDGYERVWKTERNVGDFPFEEGEIVKPVEVEIKELETKPKPRYTEGTLVKEMERLGIGRPSTYASTIKLLLSRKYVKKIRGYLYPTVIGSVVMDYLEKKYADIVDISFTAEMEKELDEVEQGKKTDKVVLQDFYRTFSKVFNENDRIIINYPTDQKCSCGKDMVLSFGRYGFYLKCECGKSRSVRNDEVAVIENGKMFIGRKNDEDSTSDGGNVKRKRSLTEKRRKGKKSS
	(1506) Reverse gyrase [Thermotoga neapolitana DSM 4359]	6	MAVNLKYHHSCINCRGVNTDERNERGLPCEVCLPEESPSDIYEALLERRTLKDYRFYHRFWREYEDFRNFFKEMFGKNLTGYQRLWAKRTILGKSFTMVAPTGVGKTTFGMVASLWLARKGKKSALIFPTVTLVKQTLERLRNMSEDAKIIGFYSSMGKEEKKKFEESFEKDDYHILVVSTQFVSRHREELSRKKFDFVFVDDVDAVLKASRNIDTLLMMVGIPENVIKKALSAIKQGKIYERPDNLKTGILVVSSATARPRGIRPLLFRDLLNFTVGRLVSVSRNITHVRISRKSRERLVELLRVFRDGVLIFTQTEEEGRNLVDYLKGQGIRVEGTWERFEENFDAFKNGDIDVLVGVQAYYGKLTRGVDLPERIKYVIFWGVPSMKFPLELDRAPKFVLTRLLRESGLIKGREVNEEELRKLAKSHFSQEEFVERVKEIFRGSAVRGEELIIPDIYTYIQASGRSSRILNGVLVKGLAVIFEEDEEIFESLRTRLLLVAEEEILEESEVDWEKLIREVEESRKSLKKEFSDTSRSLLIVVESPTKADTISKFLGKSSSRRERNILVHEAVTDEGIILFTATRGHVYDLVTRGGIHGVEEKNGIFVPVYNSLKRCRSCGYQFTEDREECPICSSKDLDDKTETLRALREISLEVDEILVATDPDVEGEKISWDVTQYLIPANGSLKRIEMHEITKYGFKKARESVRFVDFNLVKAQVVRRIQDRWIGFELSGKLQKQFGKPNLSAGRVQSTVLGWIVDREEEYRKSEKNFTLITLENGAQLEVEGKVSVDAISVSKVEETEEDIAPPPPYTTSSALSEISQKLRLGVQETMDILQDLFEKGFITYHRTDSIRVSLEGQNVARSYLRKIGKEELFTGRSWSTEGAHEAIRPVKPIDDKEIEEMMEEGLITDLTKKHLRVYSLIFNRFLASQSSPVKVKRQSVFFDVEGKELKKEYVVEILKDGWNLFMPLTISPRFEHRSYRILERKIYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFKRGYVYEDKYRRIRPTKLGVMVYSFLKERYERFVTEETTRRLEEIMDRVEKGEEDYQSTLRLLYEEIKSLTEEG
	(360) DNA topoisomerase 1 [Thermotoga lettingae TMO]	1	MANKIIIVESPAKAKTIKEILKGEYDVLSSKGHVRDLPEKEFGVNIEKDFEPTFKIIYGKEKIVQELKKKAKNKQVLLGSDMDREGEAIAWHLADILGVANEKNRIIFNEITPQAIKNAVKEPRNIDMNKVHAQLARRILDRIVGYKISPLLWKMLKTSSSAGRVQSAALKIVCEREIQRHKFQPKKFWKVQGYIGSLKFYLTHIDGKKIDMQQIDEKLAKEIEKNVKVLKVIQIKTRKIQKKAPSPFITSTLQQEAANKLGFSVKKTMQIAQQLYEGIDTPKGHRAFITYMRTDSTRVSEIAKQKAIEFITDKFGKNYLGKKVRTEKAKQNVQDAHEAIRPVNIDLTPDQVEGDLGKDQYRLYKLIWERFMASQMADAIYEETTIQFQSDRYTFESKIERRIFDGFEIILKKDKEQEITIPSGEIRISKWQIEEDETKPPARYTEASMVRALEIRGIGRPSTYATIISTLLERKYVIKSSNQLIPTVMGFVVNHYLEKKFPEIVDLQFTAKMEEALDKIEQGQKDYKELLRDFYNDFSKYLDEAQQKWLSIDMNTNLECDCKSKYKLKVGRYGLYLLCENCSKTTSLALETPAVFYENTMYFTHQEKESIETVCPVCGGKLEQMSGRYGNYIKCQNCGKTYTGFARGKCPKCSAVVEKKISKNKRIFFKCTSDNCDFISWLEPSNETCPECSQRLYYKKYRSKEVLYCQNCKKTFQLKTKK
	(1745) DNA topoisomerase 1 [Thermotoga petrophila RKU-1]	1	MNRKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKSKFGIDLEKDFEPEFVVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGKKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKTNLSAGRVQSATLKLVCDREREILRFVPKKYHKITVKFDGLTAEIDVKEKKFFDSETLKEIKSIDELVVEEKEVSLKNFSPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKDEARNLITEVFGEDYVGAKGAKRKGNTKIQDAHEAIRPTNVFMTPEEAGKYLNPDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWTTERNTGEFPFEEGESVKPVVVEIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTVVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLQEFYQSFSSVFDRNDRIVIDFPTNQKCSCGKEMRLSFGKYGFYLKCECGSTRSVRNDEIAVIDDGKIFLGRKDSESGSPDGRSIKGKRNLPEKRRKGKKSS
	(246) Reverse gyrase [Thermotoga petrophila RKU-1]	6	MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLPEESPSDIYGALLERKTLKEYRFYHEFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIIQGKSFTMVAPTGVGKTTFGMMTALWLAEKGRKSALIFPTVALVKQTLERLQKFSDGKVKILGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIKKAFSAIKQGRIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISTRSKEKLIELLEIFRDGILIFTQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKLNILIGVQAYYGKLTRGVDLPERIKYVIFWGTPSMRFSLEFDRAPRFVLARVLKEMGLIKAQENPDVEELRKIAKEHLTQKEFVEKVKEMFRGVVVKDEDLEMTIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEESETNWKELVHEVEESRKRIEGELTDTSKSLLIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVVLFTATRGHVYDLVTRGGIHGVEEEDGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPATRSLRRIEMHEITRYGFKKARENVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQEVEEERNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLKKIGKEDIFMGRSWSTEGAHEAIRPVKPIDARELEEMVEEGLIADLTKKHLRVYELIFNRFLASQSAAVKVKKQIATVELNGKRLGIEQIIEVLKNGWNLFVPLTVSPRFEHRNYKIKEKKFYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRLGVKVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEEG
	(1141) DNA topoisomerase 1 [Thermotoga naphthophila RKU-10]	1	MSKKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKNKFGVDLEKDFEPEFVVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGKKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKTNLSAGRVQSATLKLVCDREREILRFVPKKYHKITVKFDGLTAEIDVKEKKFFDSETLKEIKSIDELVVEEKEVSLKNFSPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKDEARNLITEVFGEDYVGAKGAKRKGNTKIQDAHEAIRPTNVFMTPEEAGKYLNPDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWTTERNTGEFPFEEGESVKPVVVEIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTVVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLQEFYQSFSSVFDRNDRIVIDFPTNQKCSCGKEMRLSFGKYGFYLKCECGSTRSVRNDEIAVIDDGKIFLGRKDSESGSPDGRSIKGKRNLPEKRRKG
	(1233) Reverse gyrase [Thermotoga naphthophila RKU-10]	6	MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLLEESPSDIYRALLERKTLKEYRFYHDFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTTFGMMTALWLAGKGKKSALIFPTVTLVKQTLERLQEFADEKVKILGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIKKAFSAIKQGRIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVERLVSVARNITHVRISTRSKEKLIELLEIFRDGILIFTQTEEEGKELYEYLRRFKFNVGETWSEFEKNFEDFKSGKLNVLIGVQAYYGKLTRGVDLPERIKYAIFWGTPSMRFSLELDRVPRFVLARVLKEMGLIKVQENPDVEGLRKMAKERLSQEEFVEKVKEIFRGAVVKDEDLELIIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEESEANWKELIHEVEESRKRIEGELSDKSKSLLIIVESPTKAETISRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEEDGKFVPVYNSLKRCRDCGYQFTEDRNECPVCSSKNIDDKTETLSALREISLEVDEILVATDPDVEGEKISWDVTQYLLPATRSLRRIEMHEITRHGFKKARENVRFVDFDLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLLLENGVNLEVEGKITDDVVAVVELKEVEEEKNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLKKIGKEDIFTGRSWSTEGAHEAIRPVKPIDARELEEMLEEGLITDLTKKHLRVYELIFNRFLASQSAAVKVRKQIVTVDVDGNRVGIEQIIEVLKNGWDFFVPLTVSPRFEHRTYKIKEKKFYKKHTVPLFSQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDRYKRVRPTRLGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEEG
	(1859) DNA topoisomerase 1 [Thermotoga sp. EMP]	1	MSKKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKSKFGVDLEKDFEPEFAVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGRKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKSNLSAGRVQSATLKLVCDREREILRFVPKKYHRITVNFDGLTAEIDVKEKKFFDAETLKEIKSIDELVVEEKKVSVKKFAPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERRKSNAKIQDAHEAIRPTNVFMTPEEAGKYLNSDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWKTERNTGEFPFEEGESVKPVVVKIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTIVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYESFSSVFDRNDRIVVDFPTNQKCSCGKEMRLSFGKYGFYLKCECGKTRSVRNDEIAVIDDGKIFLRRKDNESGTSDGRSVEGKGNLPEKRRKGKKGS
	(550) Reverse gyrase [Thermotoga sp. EMP]	6	MAVNSKYHHSCINCGGLNTDERNERGLPCEVCLPEDSPSDIYRALLERKTLKEYRFYHEFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTTFGMMTALWLARKGKKSALVFPTVTLVKQTLERLQKLADEKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISSRSKEKLVELLEIFRDGILIFAQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGVDLPERIKYVIFWGTPSMRFSLELDKAPRFVLARVLKEMGLIKAQENPDVEELRKIAKEHLTQKEFVEKVKEMFRGVVVKDEDLELIIPDVYTYIQASGRSSRILNGVLVKGVSVIFEEDEEIFESLKTRLLLIAEEEIIEEAEANWKELVHEVEESRRRSERELTDTSRSLLIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEENGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPSTRSLRRIEMHEITRYGFKKARESVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQEAEEEKNPLPPYTTSSALSEISQKLRLGVQEVMDILQDLFEKGFITYHRTDSTRISLEGQNVARTYLRKIGKEDIFMGRSWSTEGAHEAIRPVKPIDARELEEMIEEGLIADLTKKHLRVYELIFNRFLASQSAAVKVKKQIVTVDVDGKRMGIEQIVEILRDGWNLFVPLTVSPRFEHRTYKIKEKKFYKKHTVPLFTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEKDYQATLRLLYEEIKSLMEEG
	(328) Reverse gyrase [Thermotoga thermarum DSM 5069]	6	MPLAIYKEFCPNCGGEIEAERLEKGLACSKCIPDEISETELCEILARKSELKNYSWVCCLKSLERQFCDFFTKNLGFEPWALQRLWAKRVLSGESFTLIAPTGVGKTTFGIAMANFLPGKAYILLPTRLLVEQVAERCKTFKAKKVVAYTGKTSERKTIEAGDYEILVTTNMFLATNFELVQDQRFSFIFVDDVDSLLKSGKNIDRVLKLLGFTDEEISQAWQKVSGKLLEEKEEETMEEEEENILEESSQEDEFNEENVLQTKGKGILVVSSATLKPKTQRVKLFKSLLGFNVTPVKLTIRNVCDAVEWVDGPQQALYRLADWIRFFGKGGLVFVNREMGKDGVTTVVDFLKQQGINVSSYEELDLESMRNGLIDVAVGIATYNNALVRGVDLPEVIRYAIFIDSPKISFAIEQFDNPRNFVPLLLALREVVEDKSKIDLYLERLRRYQVFKFEKQLPKPLLEIAEYLRKNLNDESIVEKLEKAETIGLQRKEGKLFITFGDAANYLQASGRTSRLYPGGISRGISLILVWDKKAFHSLVQRLRLFYEEVDFLSADQVNWEEELKNVDADRKKIREIKKQFKPSEQLSLKSTLVIVESPNKARTISHFFGVPQQRILNGLHFWEILTGDRLLSITASIGHTVDLIEREEIYGVSKANGHFVPIYSTIKTCSKCGQQTTSEICSCGKQPDKDKLTLIKALQQVAPQFDEIIIATDPDMEGEKIGYDLMVALKPFNSNIVRAEFHEVTRQAFLKALNSPRELSKDLVKAQITRRILDRWVGFYLSQELWKAFKKYNLSAGRVQTPVLGWVIDRTNSARQKKAKLQISVKSILEGKTAALIYEHEDINFAKQLVSMLQQAQVTLEDVGQETENPPAPYNTASLLSEMGAFASAVDIMNTLQELFEQGLITYHRTTSTRVSQTGIKLAEEFLKQMGLHQIFHPRTYGTEGAHECIRPTKLLNVDDLKLWIHTGRVKFENQNLALQLYGRILNRFLASQSAPAVVQKSKLTIKLPDWSYEWTLTTKIIEPGFRTILPAKVFDLKPPLKVVWTTLRLVAKELPFTQGSLVQQMRERGLGRPSTYATIVQTLLDRKYVEERNGYLYATPLGYKVYHWLRTNYPQLTDESLTRKMEDVLDEIEAGNADYQSFLSEFYRDFLQKVFENKT
	(492) DNA topoisomerase 1 [Thermotoga thermarum DSM 5069]	1	MSKKVIIVESPAKAHTIQEILNDEYEVLASKGHVRDLPEDEFGVNLKKDFEPKFEIIKGKEKTIQELKEKTKGKSVFLASDMDREGEAIAWHLSLLLGLKNGKNRIIFSEITPKAIREALKNPREIDMKKVEAQIARRILDRIVGYKISPLLWRALKANLSAGRVQSAALRLLCERELQRYKFEPKKFWRVEGYIGEIKFKLTHIDGKKIEMQDVNEKLAKQIEQAVVTLNVTRVSRRTIRKKSPDPFITSTLQQEAANKLGFSVSKTMQIAQQLYEGVETKEGHKAFITYMRTDSTRISDYARQQAEKYIKENFGEKYIGEVRQLKKTKNVQDAHEAIRPVDVYVTPERAKNLLQSDQYKLYKLIWDRFLASQMADAVYEETTIFLESGQYGFEAKVERPIFDGFELIYGKTASKNVKIPQGTVKVDRWEIVEDETKPPARYTEASMVRALEAKGIGRPSTYATIISTLLERKYVVKRGKELVPTVIGFVVNNYLQERFPSVVDLEFTARMEEELDKIEQGKKNYKEILRDFYNDFSDYLNKAQESWFSIDFKTNKLCECGESLTLRVGKYGLYLTCKKCSKSQSVRLDELAVLDKDTMYFYEENFEKKFCPSCGEQLKQVRGKYGVFQRCEKCGKTYGLFAEGECPKCGSAVERKTSKSNKVYYKCTNQDCDFISWLEPAKEKCPNCQNQLYYKVIGSRKRLFCANCNKTIWKRKS

Family distribution

Taxonomy tree

Thermotoga