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Taxon : Alphaproteobacteria
Informations
Name
Alphaproteobacteria
Rank
class
# topoisomerases
139
Lineage and sub-taxa
Lineage
Bacteria
>
Proteobacteria
>
Alphaproteobacteria
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(170) DNA topoisomerase 1 [Sinorhizobium fredii NGR234]
1
MNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMADPRDIDISLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLQPKAVGNGEEANRLKALLDGASYVVESVEAKPVKRNPGPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDVGGETVGLITYMRTDGVQMAPEAIDAARRAIGSQFGTRYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDEVRRFLDGDMLKLYDLIWKRGIASQMASAEIERTTAEIAADNGGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDESGRLPEINARENLAKQKINATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATISTLVDRDYVEIDKRKLMPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLREFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRTCQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAVSNEPQSLGKDPHTGEEITLRSGRFGPYVQRGDGKDAKRASLPKGWTPATIDHEKALALLSLPRDIGKHPETGKMISTGIGRYGPFVLHDGTYANLESVEDVFSIGLNRAVSALADKQSKGAGGGRTAAAALKELGEHPDGGVMTVRDGRFGPYVNWGKVNATLPKGKDPQSVTVEEALALIAERAAKGGVSKGKAGNGKAARGRSSTAATKSTAAKAEKPKAAAKAKSKTAAKAKKG
(1339) DNA topoisomerase 1 [Gluconacetobacter diazotrophicus PAl 5]
1
MTDVVVVESPAKAKTINKYLGDGFTVLASFGHVRDLPPKDGSVRPDENFAMDWQADERGSRQMAAIAKALRGARHLYLATDPDREGEAISWHVRAMLEEKNLLKGVDVQRVTFNEITKSAIRAAMAQPRDLDQPLIEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIESFRAREYWTVAAQFTTPGGAAFTARLTHLAGCKLDQFDLHDEAGAMAAKAAVEAGRFAVQSVERRKVRRNPPPPFTTSTMQQEASRKLGMGAQGTMRTAQQLYEGIDLGGETVGLITYMRTDGVQMAGEAIAAIRGHIGESFGAPYVPEKARIYSTKAKNAQEAHEAIRPTDVSRTPAQMARYLNDEQRRLYELIWKRSVASQMQSAELDQVIVEIADAGGAATLRATGSMIAFDGFLKLYSEGRDDAAPKDEQDDDSRMLPPMRERDALKTGEVAADQHFTQPPPRFSEASLVKKMEEIGIGRPSTYASILTVLRDRNYVRLDARRFVPEDRGRLVTAFLTSFFERYVDTQFTAGLEEQLDDISGGRADWRDVMSAFWQDFSRAVDQTKDLKISDVISALDADLAPHFFPAHPDGSDPRVCTACGTGRLGLKLGRYGAFIGCSNYPTCQFTRRLVVDPKEDGEADTLKDGMRLLGQTPGGEDVTVRRGPWGLYVQQGEPDPEDKKAKPRRATIPRGIEGDKITLDQALGLLSLPRVVGIHPETGEQIEAGLGRFGPYVKMGAVYGSLDKDDDILTVGLNRAVDVLARKLASVRTIAPHPKDGEPVIVRKGRFGPYIQHGTMVVNVPRGEAMEDVTLDQAVALLAEKGKPLKPKGKAAAKKAPARKTAARKAPAKTAAKKAAPDGDADTQARAAKPPARKAAARKTPAGKATGKTAKGKAEPGEGAGPRTRRTATEAG
(45) DNA topoisomerase 1 [Gluconacetobacter diazotrophicus PAl 5]
1
MTDVVVVESPAKAKTINKYLGDGFTVLASFGHVRDLPPKDGSVRPDENFAMDWQADERGSRQMAAIAKALRGARHLYLATDPDREGEAISWHVRAMLEEKNLLKGVDVQRVTFNEITKSAIRAAMAQPRDLDQPLIEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIESFRAREYWTVAAQFTTPGGAAFTARLTHLAGRKLDQFDLHDEAGAMAAKAAVEAGRFAVQSVERRKVRRNPPPPFTTSTMQQEASRKLGMGAQGTMRTAQQLYEGIDLGGETVGLITYMRTDGVQMAGEAIAAIRGHIGESFGAPYVPEKARIYSTKAKNAQEAHEAIRPTDVSRTPAQMARYLNDEQRRLYELIWKRSVASQMQSAELDQVIVEIADAGGAATLRATGSMIAFDGFLKLYSEGRDDAAPKDEQDDDSRMLPPMRERDALKTGEVAADQHFTQPPPRFSEASLVKKMEEIGIGRPSTYASILTVLRDRNYVRLDARRFVPEDRGRLVTAFLTSFFERYVDTQFTAGLEEQLDDISGGRADWRDVMSAFWQDFSRAVDQTKDLKISDVISALDADLAPHFFPAHLDGSDPRVCTACGTGRLGLKLGRYGAFIGCSNYPTCQFTRRLVVDPKEDGEADTLKDGMRLLGQTPGGEDVTVRRGPWGLYVQQGEPDPEDKKAKPRRATIPRGIEGDKITLDQALGLLSLPRVVGIHPETGEQIEAGLGRFGPYVKMGAVYGSLDKDDDILTVGLNRAVDVLARKLASVRTIAPHPKDGEPVIVRKGRFGPYIQHGTMVVNVPRGEAMEDVTLDQAVALLAEKGKPLKPKGKAAAKKAPARKTAARKAPAKTAAKKAAPDGDADTQARAAKPPARKAAARKTPAGKATGKTAKGKAEPGEGAGPRTRRTATEAG
(950) DNA topoisomerase 1 [Rhodobacter capsulatus SB 1003]
1
MAVVVVESPAKAKTINKYLGSDYTVLASFGHVRDLPPKDGSVDPDADFEMKWEVAADSKKHIKAITDALANDDELILATDPDREGEAISWHLQQALASKLKKKKVSRVTFNAITKSAITEAMKAPREVDQALVDAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVCLRLIVEREMEIEAFRAREYWTVTAELTTPRGQTFTARLTVLGGKKLDKFDLTTATDAELAVQAVTSRDLTVKSVEAKPATRNPYPPFMTSTLQQEASRKFGMGAKACMSAAQRLYEAGHITYMRTDGIDMAPEAVMAARDEIKRRFGDKYVPSSPRMYKNKAKNAQEAHECIRPTDMSQSPDKLKLADDQWKLYDLIWKRTLASQMSAAVMERTTVDVGSKDNEVELRATGQVVTFDGFLKIYDQGRDDDEGEDGARLPQIMQGEPAQKGAITPEQHFTQPPPRYTEATLVKRMEELGIGRPSTYASILTTIVDRGYVRKDKNRLIPEDTGRLVTAFLSNYFRRYVEYDFTADLETELDDISAGDRPYRDVLARFWRDFSAALAETADLRIGEVLSKIDEVLGPHLYPARADGSDPRSCPVCSAGRLHLKTARSGGAFIGCGNYPDCRYTRPLSAPADGEAGVLDGKVLGEDEGAQITLRVGRFGPYVQKGEASEEIPKPPRASLPKGWSPESIDLERALQLLNLPRPIGNHPEDGALVEAGIGRFGPYVKHNSTYANLPDVEEVFTIGMNRAVEVLAQKLARGGARGSAAAAQPLKDLGEHPEGGVVQVMPGRYGPYVKWGKVNATLPKGTEPEAMTLEEALPLLEAKASKGGKKAAPKKAAKPAAEKKPAAKKAATKTATKTAAKKPAAKKAAPKKAAPEADVVED
(321) DNA topoisomerase 1 [Methylocella silvestris BL2]
1
MYVVIVESPAKAKSINKYLGKGYEVYPSYGHVRDLPAKDGSVDPDADFAMLWDVDVKSAKRLNEIARAVKDADKIILATDPDREGEAISWHVLEVLKAKKVLKDKPVERVVFNAITKSAVLEAMQHPRQIDVALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEAFVAREYWSIVAHLRTQADAPFTARLVGADGKKITRLDVGTGAEAAAFKTDLENATFRVAEIEAKPAKRHPSAPFTTSTLQQEASRKLGFAPARTMQLAQRLYEGADIDGETVGLITYMRTDGVDLAPEAITSARSVIARQFGDAYVPKAPRKYTVKAKNAQEAHEAIRPTDLARLPRAVARALEPDQAKLYELIWTRTIASQMESAELERTTVDIEALAGARKLDLRATGQVVRFDGFLKLYQEGRDDEDDDESARLPDMAKDERLKRERIEADQHFTEPPPRFTEATLVKRMEELGIGRPSTYASTLAVLRERDYVRIEKKRLHPEDKGRLVTAFLEAFFARYVGYDFTADLEEKLDRVSNHEIDWKQVLRDFWLDFSGALAGTKDLRTTEVLDRLNEILGPHIFPPKEDGSDPRGCPSCGEGKLSLKLGKFGAFIGCSNYPECKFTRTLAAPDGAEANGGERPGVKSLGVDPDSGEEITLRDGRFGVYVQQGEGEKPKRSSLPPTIAPADLTLEQAIALLSLPREVARHPESKEPIVAGIGRYGPYVQHGKTYANVAKDEDIISIGANRAIDLIVAKESGLTGRRFGASESAPARVLGEHPAGGAVSVKAGRYGPYVTHGKINATLPKEADPTTLTLEGAVALLAAKASGGGAPMQGRLLGDHPSGGPITVRAGRFGAYVNHGKTNATLKRDASAETITLEEAIRLIEDKEAAGGGPRKAAAPKKAAKSSAAAKKAAPNAKNKTAPANDEDPPFEPSPNRKPAAKAAAAAHKKPAAKAAAAKLKQAKQA
(739) DNA topoisomerase 1 [Asticcacaulis excentricus CB 48]
1
MNLVIVESPAKAKTINKYLGKDYTVLASYGHVRDLPSKDGSVKPDEDFAMSWEVDAKASKRLSDIADAARKSERVILATDPDREGEAISWHVLEVLNKKKVLKEKVVERVTFNAITKASVQEAMAAPRQIDMELVEAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALKIIVDRELEIEKFKSEEYWTVDAEVSANSPPFTARLNVLNGKKLAKFDLENAEKAEAARKAISLSKFAVESVEQKPGKRTPPPPFTTSTLQQEAARKLGFSAQRTMQTAQKLYEGVDIGGETTGLITYMRTDGVFIDPAAIGEIRKAVGERFGSAYVPSEPRLYKVKAKNAQEAHEAIRPTSIFRRPETLRLEGDQARLYELIWKRTMAAQMEAARVEKTTIDLLNHDKSIGLRSTGQVITFDGYLALYEEGKDDETDEDGGRLPQLRTGTLVDVHDIKPAQHFTEPPPRYSEASLVKRMEELGIGRPSTYASILSVLRDRDYVRMDKNRFIPEDKGRLVTAFLDQFFSRYVQYDFTADLEEKLDLVSAGDLNWKALLREFWQDFHAKAGEISEFRVSEVLDRLNDALAPHIFPDKGDGSNPRACPTCGTGQLSLKTSRFGAFVGCSNYPECKYTRPVGNPENASEVAAASGDRELGRDPETGKVVALKIGRFGPYVQLGEAESKDDKPKRSSLPKAWPPASIDLDRALKLLSLPRKVGDHPEDGKPITAALGRFGPFIEHEKTYANLPSFDEIFEVGLNRAVVLLAEKRANAKGKASTVATLKELGAHPESGDAIQVMAGRYGPYVKCGKVNATIPKDTAPEDVTLEQALALIEAKGGVKKTAAKKTTAKKAAPAKKPATKKATTSKKAPAKKAKAEA
(1418) DNA topoisomerase 1 [Acetobacter pasteurianus IFO 3283-01]
1
MTDVVVVESPAKAKTINKYLGDGYTVLASFGHVRDLPPKDGSVLPDEDFAMKWQSDERGMKQVAAIAKALKGAHRLYLATDPDREGEAISWHVRAMLEERKALKGVDVQRVTFNEITKSAIRYAMEHPRDLDFPLIEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIEVFKPREYWSVIASLLTPAGAAFTARLTHLNGKKLDQFDLHNAELAEAAKKAVEAENLAVKSIERRKVRRNPQPPFTTSTLQQEASRKLGMSAQTTMRTAQQLYEGMDLGGETVGLITYMRTDGVTMAQEAINAIRQHIGQKIGTEYVPAKPRIYTSKVKNAQEAHEAVRPTDVSRTPESVARFLNNDQRRLYELVWKRAVASQMESASLDQVAVDIAGPSGQTVLRANGSIITFEGFLKLYREGRDDTEKAADDDARMLPSMQEKDPLKREKVDAEQHFTQPPPRYSEASLVKKMEELGIGRPSTYASILTVLQDRSYVRLENRRFIPEARGRLVTAFLVSFFERYVDTGFTASLEELLDDISGGRAQWKQVLAAFWNDFSKAVSGTKELTITDVLNALDKDLGPFFFPERADGSDPRVCPSCGTGRLGLKLGRYGAFIGCSNYPECQYTRRLTSDSAEEGDDAALKDGMRLLGQNPETGEDITVRQGPWGLYVQQGEPNPEDKKAKPKRASLPKNINGESITLDQALGLLSLPRLVGIHPETGEPIQAGLGRFGPFVKMGAVYGSLDKDDDVLTIGLNRAVDALAKKLASIRNLGVHPKDGEPVMVRKGRFGPYVQHGQMVATLPRGTDMDAVTLDEAVALLADKGKPLKAKAGAKKKATTTKTAAKKKTATKSTAKADAEGAEKAAPKKKAPAKKKATTTTRKKKAETE
(587) DNA topoisomerase 1 [Brucella microti CCM 4915]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1830) DNA topoisomerase 1 [Brucella suis VBI22]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRITNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRNIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1690) DNA topoisomerase 1 [Brucella melitensis NI]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEILRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYPRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(20) DNA topoisomerase 1 [Pseudovibrio sp. FO-BEG1]
1
MESPAKAKTINKYLGKDYTVLASYGHVRDLPPKDGSVLPDDDFAMSWSVDSKSQKRLSDIASAVKEADRLILATDPDREGEAISWHVLEVLKKKRVLKDKKVERVVFNAITKSSILEAMKNPRELDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCQRENEIETFLSQEYWSILANLNTPENAPVQARLTGFDGQKITRLDIKNEQEATTIKQMLDGANFSVSNVESKPQRRNPYAPFTTSTLQQEASRKLGFAAARTMQVAQKLYEGANIGGETTGLITYMRTDGVQIAPEAITSARGVIASRYGDEYVPEKPRMYSSKAKNAQEAHEAIRPTDLTRHPRDMAKFLDEDGARLYELIWKRTIASQMESAVLERTTVDIDAVNGAKKAALRASGSVVRFDGFLTLYQEGKDDEEDEESKRLPPMTRGDSLGRKGIEANQHFTEPPPRFTEATLVKKMEELGIGRPSTYAATLQTLRDRGYVELDKKRLIPQDKGRLVTAFLEDFFNRYVEYDFTASLEDQLDKISAGDLEWKAVLRDFWNPFHEICDEVIKRSNTEVLDALNETLKAHVFPDKEDGSDPRKCPKCDTGRLSLKVSRFGAFVGCSNYNKDKKDGKEPNENPPHCDYTRQLTSGGDSDAGAAADGPQVLGIDPETGLEVSLRTGRFGPYVQLGEEAKPKRSSLPRGWSTADLDLEKALQLLSLPREVGTHPEDGKTISAGLGRFGPFVLHDGTYANLDSPDEVFSVGINRAVTLLAEKRAKGGGRGAAAKPLKELGNHPDGGAINVYSGRYGPYVKWEKINATLPKDVAPEAVTLEQAIELVNAKAATKGKKKAPAKKAAAKKTTAKKAAPKGALKEFGDHPDGGAMELRDSGRLGVRIKWGKEFVSLPKGTDPETVTREQAIELINAKKG
(1747) DNA topoisomerase 1 [Candidatus Liberibacter asiaticus str. psy62]
1
MNVIIVESPAKAKTISKYLGSNYKVLSSFGHIRDLPAKKGSVLPEKEFEMIWNIDPSSQKHLQNIIHAVKSSTILILATDPDREGEAISWHVLDVLRQKNLIEKTKIQRVSFNAITKQVVLNAMKSPRDINLDLVNAYLARRALDYLVGFNLSPILWQKLPGARSAGRVQSVALRLICNRENQIESFVSEEYWSLSVLLETPRNDKFTAHLTDFNGQRIEKKSISNKKEADDLISFVKKATYSVEKIENKPIKRNPWPAFTTSTLQQVASSRLGFSASHTMRIAQKLYEGIDVNGEIVGLITYMRTDGVHMSPDALEAVRRSITSHYGDHYLPEKPRIYSSKSKNAQEAHEAIRPNDFDFLPSKMKQFLDSDQFQLYNLIWKRSVASQMASAKFERTTVNIIATYNDQIGHLRTTGSLLCFDGFLKVWENQYDQEKNSEEDILLPYISANEQLIATETNASQHFTEPPPRYSESSLIKKMEEIGIGRPSTYATILETLYKRKYVIAEKRKILPQNTGRIVTAFLENFFSQYVEYDFTADLEEKLDEISTGKLNWKEVLHEFWEEFIEKIDSIKKLRISNVLDILNDTLSSVIFPPKENNEDSRTCPECHTHSLSLKLSSKYGAFVGCTNYPECKYTRQLTSNPQDIPEMKESVLLGNDLETKESVTLRSGRFGLYVQRGDGKDAKRCSLPKTWKSDSVDYDKAMSLLSLPREIGIHPETQKNIIAGTGKYGYYLNHDGAYTKLESIEQVLTIDLEQAISCITEKKKIEKSSRKNSKNQGHVIGTHPEGGSITVHNGRYGPYLHWKKINASLSKEESPDTVDLEKALKILNIKKQKKL
(1624) DNA topoisomerase 1 [Agrobacterium sp. H13-3]
1
MLTDQFQRKNNMNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMSWEVDSASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKRVLGDKPVKRVVFNAITKKAVLDAMANPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVSLRLVCDREAEIERFVSEEYWNISALLKTPRGDEFEAKLVSADGKKLQGRSIKTGDDANRLKALLEGATYIVDTVEAKPVKRNPGPPFTTSTLQQAASSRMGFSASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQMAPEAIDAARRAIGEQFGDRYVPEKARFYSTKAKNAQEAHEAIRPTDFNRTPDQVKRYLDADQLRLYDLIWKRGIASQMASAEIERTTVEILADKDGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDDEGRLPQINARENLAKQKINASQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLKTLSDREYIIIDKRKLIPHSRGRLVTAFLESFFAKYVEYDFTADLEEKLDRISAGELDWKQVLRDFWKDFFAQIEDTKELRVTNVLDALNEVLAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNFTRQLTSDGSEAEASVSNEPKALGADPMTGEELTLRSGRFGPYIQRGDGKEAKRSSLPKGWKPEEIDHEKALALINLPRDIGKHPETGKMISAGLGRYGPFLLHDGSYANLESIEDVFSIGLNRAVTVIAEKQSKGPGRGRNGTPAALKELGDHPDGGPITVRDGRYGAYVNWGKVNATIPKGQDPTSVTLDESLVLIAERIAKTGTGGKPAKAKKPAAKKADGDTAAKPKATKAKAATKSKTAAKPKAAAKPKKAES
(1515) DNA topoisomerase 1 [Agrobacterium fabrum str. C58]
1
MNVVVVESPAKAKTINKYLGSGYKVLASFGHVRDLPAKDGSVLPDQDFEMSWEVDSASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKRVLGDKPVKRVVFNAITKKAVLDAMANPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFVSEEYWNISALLKTPRGDEFEAKLVSADGKRLQSRGIKTGEDANRLKALLEGATYVVDTVEAKPVKRNPGPPFTTSTLQQAASSRMGFGASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQIAPEAIDAARLAIGEQFGERYVPEKARFYSTKAKNAQEAHEAIRPTDFTRTPDQVKRYLDADQLRLYDLIWKRGIASQMASAEIERTTVEILADKNGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDDEGRLPQINARENLAKQKINASQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLKTLSDREYIVIDKRKLIPHSRGRLVTAFLESFFTKYVEYDFTAALEEKLDRISAGELDWKQVLRDFWKDFFAQIEDTKELRVTNVLDALNEVLAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNYTRQLTSDGAEADAAASNEPKALGADPMTGEELTLRSGRFGPYIQRGDGKEAKRSSLPKGWKPEDIDHEKALALINLPRDIGKHPETGKMISAGLGRYGPFLLHDGSYANLESIEDVFSIGLNRAVTVIAEKQAKGPGRSGTPAALKELGDHPDGGAITVRDGRYGAYVNWGKVNATIPKGQDPASVTLDESLVLIAERIAKTGTGGKPAKAKKTTAKKADGEAAAKPKATKAKAATKSKAAAKPKAAAKTKKAAE
(1503) DNA topoisomerase 1 [Agrobacterium vitis S4]
1
MNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDTASAKRMKDIADAMKGADALFLATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMAAPRDIDGDLVDAYLARRAMDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRENEIERFVSEEYWNLSALLKTPRGDEFLARLVSADGKRLQARSVGNGDMANRLKDLLDGANYVVESIEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARSAITQQFGPRYMPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRYLDADQLRLYDLVWKRGIASQMASAEIERTTAEILADKAGEKAGLRAVGSVIRFDGFIAAYTDHREEGEKSDDDDEDGRLPEINAREALAKQKVNATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATLKTLSDREYVVIDKRKLIPEAKGRLVTAFLESFFTRYVEYDFTADLEEKLDKISAGELNWKDVLREFWQNFFAQIEGTKELRVTNVLDALNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNFTRQLSADGGTEAEAVGNEPKALGEDPTTGEQITLRSGRFGPYVQRGDGKEAKRSSLPKGWSPTDVDFDKALSLLSLPREVGLHPETGKMMTAGLGRYGPFVLHDGTYANLDGIEDVLTIGLNRAVTVLAEKQANPGGRGRAAPAALKEIGDHPDGGAITVRDGRYGPYVNWGKINATIPKGMDPQAVTMEEAIALIVERAAKEGSGKTKAKPAAKSASAKKAPAKKPAAKATKADADDAADAKPKKAAAKPKATKPKAKPAAKTEKA
(994) DNA topoisomerase 1 [Sinorhizobium fredii HH103]
1
MTMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMADPRDIDISLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNIVALLKTPRGDEFEARLVSADGKRLQPKSIGNGEDANRLKALLDGASYVVESVEAKPVKRNPGPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDVGGETVGLITYMRTDGVQMAPEAIDAARRAIGSQFGPRYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRVLDGDMLKLYDLIWKRGIASQMASAEIERTTAEIAADNGGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATISTLVDRDYVEIDKRKLMPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLREFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRTCQVCGTGKLSLKLGKYGAFVGCSNYPDCNYTRQLSSDSNGDAEAAVSNEPQSLGKDPHTGEEITLRSGRFGPYVQRGDGKDAKRASLPKGWTPATIDHEKAIALLSLPRDIGKHPETGKMISTGIGRYGPFVLHDGTYANLESVEDVFSIGLNRAVSALADKQSKGAGGARGRTAAAALKELGEHPDGGAMTVRDGRFGPYVNWGKVNATLPKGKDPQSVTVEEALALIAERAAKGGVSKGKSAKGRSAATKSTAAKAEKPKAAAKAKSKTAAKAKKG
(389) DNA topoisomerase 1 [Sinorhizobium meliloti AK83]
1
MNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLRKKKVIGDKPVKRVVFNAITKKAVLDAMAEPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPPKAIGNGEEANRLKSLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFDRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLVPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAAANEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPAAIDHEKALALLSLPRDIGPHPESGKMISTGIGRYGPFVLHNGTYANLESVEDVFSIGLNRAISVLADKQSKGAGGGRASAAALKELGEHPDGGAITVRDGRFGPYVNWGKVNATLPRGKDPQSVTVEEALALIAEREAKGGVTKGKAAKGKPTGGKSAGTKSAKAASAGTAKAEKPKSAAKTKTKAAAKAKKD
(330) DNA topoisomerase 1 [Paracoccus denitrificans PD1222]
1
MPVVVVESPAKAKTINKYLGDDYTVLASFGHVRDLPPKDGSVDPEADFAMKWEVASESKKHVKAIRDALAADPNLILATDPDREGEAISWHLLETLAPALKKGAEVSRVTFNAITKAAVTEAMANPRQIDQPLVDAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVALRVIVDREMEIEAFKAREYWSVHARLATPRGDEYDATMTVFGGKKLERFDIASEEQAKLAVAAITSRDLRVASVAAKPASRNPWPPFMTSTLQQEASRKLGLGARACMSAAQRLYEAGHITYMRTDGIDMAPEAVMAARDAIKARFGAEYLPKSPRMYKNKAKNAQEAHECIRPTDMMLSPDRLPVSDKDQKALYDLIWKRTIASQMESARMERTTVEIGSADGQVGLRANGQVMLFDGFLRVYDQGRDDEEDEDSRRLPSIEEGERAEKRSVTPEQHFTQAPPRYTEATLVKRMEELGIGRPSTYASIVTTIQDRDYVRKEQNRLIPEDKGRLVTIFLLKYFPRYVSYDFTANLEGELDDISSGERAYREVLRRFWRDFTAALEGTSELRITEVLDAIDEALAPHLYPPRADGSDPRECPLCHKGRLHLKTARSGGAFIGCSNYPDCRFTRPISSPDAEVVGDAVLGVDNGDEISLKNGRFGPYVQRGEATAENPKPPRASIPKGWDLASVDLERALALLSLPREIGSHPEDGVPVEAGIGRYGPYVKHGAKYANLPDVDEVFTIGMNRAVEVLASKQVRGRAAVAAPLAELGEHPEGGSVQVMSGRYGPYVKWGKVNATLPRDLEPGAVTLERALELIAEKAAKSGKKPAKKAAAKKPAAKKPAAKKPAAAKAKKAG
(1266) DNA topoisomerase 1 [Rickettsia heilongjiangensis 054]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRIAFNEITKKAIIHAVENPRKLDNNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTEKLKSQKFHVDKIEKKQQKRQPQPPFITASLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDKAEEENKMLPPLKEQEPLKTKKVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKVCPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGEQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGKFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKPA
(1207) DNA topoisomerase 1 [Rickettsia peacockii str. Rustic]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKTGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTQVNDQKLEKFSIINEKNAKDLTKKLKSQKFHVDKIEKKQQKRQPQPPFITSSLQQEAVRKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDEAEEENKMLPPLKEQEPLKTKEVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGTLEWKAALNNFWSGFNHNIESVNEQNITEIISYVQKALDYHLFGENKESKICPSCHTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGKFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
(623) DNA topoisomerase 1 [Sinorhizobium medicae WSM419]
1
MSWRRYWRAWSPKQLFQRMSMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKASDGLILATDPDREGEAISWHVLDLLRKKKVLGDKPVKRVVFNAITKKAVLDAMAQPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPAKAIGNGEEANRLKTLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQMAPEAIDAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKRAGLRATGSVIRFDGFIAAYTDMKEDGEQTDDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLLPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDRISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSSGDAEAAASNEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPATIDHEKALALLSLPRDLGPHPETGKMISAGIGRYGPFVLHNGTYANLESVEDVFSIGLNRATSVLADKQSKGAGGAGGRTGAAAVKELGEHPDGGAITVRDGRYGPYVNWGKVNATLPRGKDPQSVTVEEALAFIAERAAKGGVTKGKTAKGKSAGRKQAGTKTAKAAGTATAEKPKRAAKTKTKSAAKAKKD
(659) DNA topoisomerase 1 [Roseobacter denitrificans OCh 114]
1
MPVVVVESPAKAKTINAYLGDDYTVLASYGHVRDLPPKDGSVNPDADFEMLWEVGYDSRKHVKAIADALKEDNALILATDPDREGEAISWHLQEALTKRKSIKKDTPVSRVVFNAITKAAVTEAMQNPRQVDMPLVEAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVTLRLIVEREMEIEAFRAREYWSVKALLATPRGQEFEAKLTVLAGKKLDRFDIENQTQAELAVQAITSRDLSVKSVEAKPANRNPSAPFMTSTLQQEASRKFGMGARQTMSTAQRLYEAGYITYMRTDGIDMAPEAVTAARDAIKTLYGSKYVPEKPRIYKNKAKNAQEAHECVRPTDMMTKAEDLKTTDADQRKLYDLIWKRTLACQMEAARMERTTAEIASEDGQVGLRATGQVMLFDGFLRVYEEGRDDVAVVDDDDKRLPQIDQGDRLDKRTVTPEQHFTQPPPRYTEATLVKRMEELGIGRPSTYASVVTTIQDREYVRKDKNRLIPEDKGRLVTAFLSNYFRKYIGYDFTADLEDQLDTVSAGNADYKEVLGRFWRDFSAAIAETADLRITEVLEKINEVLEPHLFPPNEDGSDPRLCPNCGAGRLSMRTARSGGAFIGCSNYPECRYTRAFGPPGEEDDSGIPPEGKLLGEDGDDKIYAFKGRFGPYVQRGEVTEDNKKPPRQSIPKDWPPEDVDLPQALKLLSLPREIGPHPEDGIMVWANIGRYGPYLKHAPSTSDRGGTNANLESIEEVFTVGMNRAVQLLAEKVASRGRRGGAAKTLRDLGEHPEEGGPVAIMEGKYGPYVKWDKINATLPKDSDPAELTMEAAIALIDEKAASKGKKRRKAAPKKAAAKKTATKKAAPKKTAAKKKAPAKKAKE
(1205) DNA topoisomerase 1 [Ochrobactrum anthropi ATCC 49188]
1
MNVVVVESPAKAKTINKYLGSNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSSKRLADIVKALKDSDGIILATDPDREGEAISWHVLEVLNQKKALKGKTVKRVAFNAITKKAVLDAIANPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVADRESEIERFIREEYWNIAALLKTPRNDGFTARLTAVDGKKLGKLDIKNGEQATAIRTMLEGASFKALSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIGKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRYLDDDQARLYELIWKRAIASQMQAADIERTTVDIEAVNSSRSAMLRANGSVTKFDGFLAAYMDHREEEDDDEDSAKLPEIRSGEALAREKIDATQHSTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDREYITIDKRKLIPEPKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKDVLRDFWRDFSGNVDDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGMLSLKLGKYGAFVGCSNYPECKYTRQLGGDANGESAAADEPKSLGKDPFTGEEITARTGRFGPYVQRGEGKEAKRASLPKGWTVDTLDHEKAVALLSLPRDIGQHPETGKMISAGIGRYGPYVSHDGTFANLENAEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGSITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKSKKTPARKASASTEKKAAAKKPAAKKAPAKAKSTAKPKAKSKAETVEE
(1623) DNA topoisomerase 1 [Rhodopseudomonas palustris CGA009]
1
MNLVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDADFQMIWEVDPKAASRLNDIAKALKGADKLILATDPDREGEAISWHVLEVMKQKRALKDQQVERVVFNAITKQSVTDAMKHPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRETEIEKFVPREYWSLIATMATPRGETFEARLVGADGKKIQRLDIGTGAEAEDFKKAIEAANFRVATVEAKPARRNPYAPFTTSTLQQEASRKLGFAPAHTMRVAQRLYEGVDIGGETVGLITYMRTDGVQIDSSAITQARKVIAEDFGNAYVPDAPRQYTAKAKNAQEAHEAIRPTDLSRRPSDVSRNLDSDQARLYELIWIRTVASQMESAELERTTVDIEAKAGSRVLELRATGQVVKFDGFLAAYQEGRDDDSEDEDSRRLPAMSENEALKREALAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVRLEKKRLHGEDKGRVVVAFLESFFTRYVEYDFTAGLEEDLDRISNNEVSWKQVLSDFWRDFIGAVDEIKDLRVAQVLDVLDEMLGPHIYPAREDGGDPRQCPSCGTGKLNLKAGKFGAFVGCSNYPECRYTRPLASDSAGDADRVLGTDPDSGLEVAVKSGRFGPYIQLGEAKDYAEGEKPKRAGIPKGTSPSDVDLEMALKLLALPREVGKHPETGQPIKAGIGRFGPYVQHEKTYASLEAGDDVHTIGLNRAVTLIAEKVAKGPSKGRFGSDPGKALGDHPSLGAVAVKKGRYGAYVTAGGVNATIPNDKTEDTITLPEAIALLDERAAKGGGKAKKAPAKKAAAKKASADGEAKPVKKAAAKKAKPKAEGAAASKARAPVAAKTAAKKAAKPKDAAKSSAAKNG
(1366) DNA topoisomerase 1 [Oligotropha carboxidovorans OM4]
1
MNLVIVESPAKAKTINKYLGSSYEVLASYGHVRDLPAKNGSVDPDANFQMIWETDPKAASRLNDIAKALKGADKLILATDPDREGEAISWHVLEVMKQKRALKDQKVERVVFNAITKQSVTEAMNNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREIEIEKFVAREYWSLVATLATPRNDTFEARLVGADGKKIQRLDIGTGAEAEDFKKALETAAFTVSLVEAKPARRNPQAPFTTSTLQQEASRKLGFAPSHTMRIAQRLYEGIDIGGETTGLITYMRTDGVSIAPEAIPALRKVIAEEYGSNYVPSAPRQYTSKAKNAQEAHEAIRPTDVSRRPAKLKARLDNDQYRLYELIWMRAIASQMESAELERTTVDITAKAGARTLELRASGQVVKFDGFLAVYQEGRDDDPEDEESRRLPAMSEGEALKRESLAVTQHFTEPPPRYSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLSAEDKGRVVVAFLQKFFARYVEFDFTADLEEQLDKISNNEVAWKNVLSDFWRDFIGAVDEIKDVKVSEVLDVLDAMLGEHIYEPRADGGDPRQCPSCGTGRLNLKAGKFGAFVGCSNYPECRYTRPLAASSGTSDRVLGKDPKTNLDVAVKAGRFGPYIQLGEPNDYAEGEKPKRAGIPKNMSPADVELDLAIKLLSLPRDVGPHPEDGEIITAGIGRFGPFVRHGKTYASLEAGDDVYTIGLNRAVTLIAEKIAKGPSRRFGADPGKEVGDYPARGGKIMLKKGRYGAYVTIDGINATIPDDKEPDQITLEEAIALIEARAAKGGKAKRAPKKAAAKKAAPKKKATAKKKADSEPESGAKPAKKAATRTAPKARTSTAKPAAKTAAKAKPTAKKSAGKARG
(184) DNA topoisomerase 1 [Hyphomicrobium sp. MC1]
1
MNVVIVESAAKAKTINKYLGSGYKVIASYGHVRDLPAKDGSVEPDHDFNMHWEVDTKSQKIMREIAEAVKKADKLILATDPDREGEAISWHILQILNQKKALGKDTEVERVAFNAITKQSILAALKEPRKIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLVCDREAEIEAFKTEEYWTIEALLSTAKNEDVRSRLVAIDGTALKKLDIKDEATATAIRKALLGQDFRIASVEKKATKRNPFPPFTTSTLQMDASRKLGFSAKQTMQIAQRLYEGVDIGGETVGLITYMRTDGVQIVPEAVSQIRDVISAEYGKNYTPFAREYKTKAKNAQEAHEAIRPTDPRRKPDQVRKHLEKDQAALYDLIWKRTIASQMAAADIEQTTAEIDVKGSDGKAYGLRANGSVLMFDGFLKVYEEGRDDRVRTIEKGKDDTADEDDDSRRLPPLAVGDRLKDKEISADQHFTQPPPRFSEATLVKRMEELGIGRPSTYASTMAVLVDRDYVRIEKKRLIPEDKGRLVIAFLESFFKRYVEYDFTADLEEKLDLISNDELEYKQVLRDFWRDFMAAVGEIKDLRVGDVLEALNEMLGPHVFPDKGDGSDPRLCPKCGTGRLSLKISGKYGAFIGCGNYPECNYTRQLTQSSDGDAAALDGKILGYNDDGLAVTMKTGRFGPYIQLGEAEGDEKPKRSSIPRGIDAATLDFERAMQLLSLPRDVGEHPDEGGMITAGLGRFGPFIVHEKDGAKTYVNLESLEDVFTVGLNRAVTLIAEKRAGGGKSRFQRNAPKVVKDLGQHPSEGGAVQVLEGRYGPYVTHNKVNATVPKAKNPAELTMDEAVALINERTANGGGKKGKPARGAKAKAAKDDKPAKAPKADKAAAPKAAKKPAATKTAAAKAEKAPAKKAPATSAGAKKLARAKA
(396) DNA topoisomerase 1 [Hyphomicrobium denitrificans ATCC 51888]
1
MNVVIVESAAKAKTINKYLGSGYKVIASYGHVRDLPAKDGSVEPDHDFAMQWEVDSKSQKIMREIADALKNADKLILATDPDREGEAISWHILEILNNKKALKKGTEVERVAFNAITKQSILAALKEPRKIDEPLVEAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFKTDEYWTIEALLTTSRGDDVKTRLVAIEGTALKKLDIKDEASATAIKAALEGRDFRVASIEKKAAKRNPYPPFTTSTLQMDASRKLGFSAKQTMQIAQRLYEGVDIGGETVGLITYMRTDGVQIVPEAVSQIRDVISAEYGKQYTPFAREYKTKAKNAQEAHEAIRPTDPRRKPDQVRKYLEKDQAALYDLIWKRAIASQMAPADMEQTAVEIEAKGSDGKNYGLRANGSVLLFDGFLKVYEEGRDDRFRYIEKGKDDPEGEDEDRRLPALAEGDHLKDKEISADQHFTQPPPRFSEATLVKRMEELGIGRPSTYASTMAVLVDRDYVRIEKKRLVPEDKGRLVIAFLESFFKRYVEYDFTAELEEKLDLISNNELAYKEVLRDFWRQFIASVGEIKDLRVGDVLEALNEMLGPHVFPDKGDGSDPRLCPKCNQGRLSLKISGKYGAFIGCGNYPECNYTRQLSQSANNGEAALDGKVLGYNDDGIAVALRTGRFGPYIQLGEATGDEKPKRSSIPKGIDAATLDFEKAMQLLSLPRDVGVHPTEGGMITASLGRFGPFILHEHDGAKTYVNLGNVEDVFTIGINHAVTLLAEKRAGGGKSRFQRNAPKVLKDLGAHPSEGGPVQVLEGRYGPYVTHNKVNATVPRGKDPSALTMDEAVALIAERIANGGGKKSKASRSSAKPKAAKAAKPAKGEAAPAAKRTAKPAAAKKAAPAKKSAAKPAAKKLAKAKA
(1146) DNA topoisomerase 1 [Rhodomicrobium vannielii ATCC 17100]
1
MNIVIVESAAKAKTINKYLGADYKVIASYGHVRDLPAKDGSVLPDNDFEMTWEVEADSNRIVNEIAKAVKGADRLILATDPDREGEAISWHLLKILEQKRALNGVSVERVAFNAVTKDAILTAMKNPRKIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVVDREAEIEAFRTREYWTVEAALKNGGGDAFTARLVARAGKKLDKFDIPNEALAHAYRDAIKGQSYRVDSVDAKDHKRNPAPPFTTSSLQQEASRKLGLSPRQTMQIAQKLYEGIDIGGETVGLITYMRTDGVQIVGEAIAQARGQIESQFGARYVPSAPRIYKTKAKNAQEAHEAIRPTDFGRQPDKLRGLSAEEARLYKLIWQRAVASQMASADIERTTAEISVPGKDGVPYGVRATGSVVKFDGFMRLYEEGRDDTDDEDSARLPPLKQGEALKDSGVTAAQHFTEPPPRYTEATLIREMERLGIGRPSTYASTMAVLREREYVKLEKKRLVPEDKGRLVTTFLEAFFKRYVEYDFTAYLEDRLDQISDGKLDWKALLREFWQDFIGAVTDIKDLRVTQVLDALNELLGPHIFPAKEDGGDPRLCPLCNQGQLSLKIGKFGAFVGCSNYPECRYTRQLKTGENGNGDGAAPAGDTVLGNDPETGLAVCLKNGRFGPYIQLGEGGDGEKPKRASIPGGMGLADVDFAYALKLLALPREVGPHPETQKTIMAGFGRYGPYVEHDGKYVKIDAEEVFTIGLNRAVTVIAEGGTGGKGRAPKTEPIKVLGEHPEKGGKMEVLAGRFGPYIKWGKVNATIPKGTEPQDVTVDEAVRLIAARIEAGDGKKGRGKPTKSAKAPAKEKKPAKAKTADAGDEAEAPKKAKTAAPKKAAANGKAKSSAKEKSAKADEADKKPKAKASAKKTTSKAAGGTT
(1538) DNA topoisomerase 1 [Pelagibacterium halotolerans B2]
1
MKVVIVESPAKAKTINKYLGKDFEVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDTNSKKRLADITRALKGADELILATDPDREGEAISWHLLDALKAKKAIKADMPVKRVVFNAITKDAVTTAMQHPRDIDAPLVDAYLARRALDYLVGFTLSPILWRKLPGSRSAGRVQSVALRLVTEREEEIERFKPQEYWSVIPTLNQTGKSFATRLYSVDGDKTDKLAIKTGEDAQGLKTAIEKGNFKVASVDRKPTKRNPYAPFTTSTLQQDASSRLSLSPSRTMQIAQRLYEDGLITYMRTDAVQMAPEAIEAARRVIGKEFGSEYVPEKPRFYSTKAKNAQEAHEAIRPTDLGKHPDTLRNLDPDQHKIYQLIWRRALASQMRSAEIERTTADIDVLAAGRAITLRATGSVVTFPGFLGVYGVEKTDEDDEDGKDLPALNVGDTPALENVAIEQHFTQPPARYTEASLIKKMEELGIGRPSTYAATLKTLQDRDYIKLEKRAIMPEDRGRLVTAFLQSFFTKYVEYGFTAGLEEELDEISAGEIDYKEVLRRFWKDFSHQADEIKDLRVSEVLDALNDLLGHHIFPERPDGTDPRLCPTCGTGQLSLKLGKYGAFIGCSNYPECRHTQQLAESATGQASEAAQGDGVLGADPETGAEIYLKTGRFGPYVQLGEDAKDAKRSSIPKGWDAGSMDLEKALKLLSLPREVGLHPEDGKPISAGIGRYGPFVLHEKTYANLPDVEEVFTVGLNRAVDLIAQKRAGGGRGGRGAAVAAIQTFEHDDGPITVRAGRYGPYVNQGKVNATLPKDLAPEAVTLEKALELIAAKGGSKSKAKAKPKPAAKKPAAKKTATKKPAAKKKAEA
(503) DNA topoisomerase 1 [Mesorhizobium ciceri biovar biserrulae WSM1271]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHIRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAALLGTPRNENFEARLTAFDRKKLQKLDISNKAQADDIKSMLEGATFKAVSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSASRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRQYTAKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAIASQMQPAEIERTTAEIEAVNGSRTAELRAIGSVVRFDGFIAAYTDQKDDDAEDEENRRLPEIRAGEQLARQAINATQHTTEPPPRYSEASLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFKRYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGEDGTKVIGKDPYTSEEITLRSGRFGPYLQRGDGKEAKRSSLPKGWTAESIDHEKALALLSLPRDVGQHPETAKMISAGLGRYGPFVLHDGTYANLESIEDVFSIGLNRAVSVIAEKQLKGKGGRNGGTAAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTMEDALALIAEKEAKGGGGKKPFRKAAAAKAPATKKVAAKKPAAKKPAAKKKG
(662) DNA topoisomerase 1 [Mesorhizobium opportunistum WSM2075]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAAILGTPRNEAFEARLTAFERKKLQKLDISNKAQADDVKAMLEGAAFKALSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSATRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRVYTTKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAISSQMQPAEIERTTVEIEAVNGSRTAELRAVGSVVRFDGFIAAYTDQKEDDAEDEENRRLPEIRVGEQLARQAINATQHTTEPPPRYSEATLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFERYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGEDGTKVLGKDPYTAEEITLRSGRFGPYIQRGDGKEAKRSSLPKGWTPESIDHEKALALLSLPRDVGKHPESGKMISAGLGRYGPFVLHDGTYANVDSIEDVFSIGLNRAVTVIAEKQSKAKGGRNGGTAAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTIEDALALIAEREAKGGGGKKPFRKAASPATKKAATKKPAAKKKG
(47) DNA topoisomerase 1 [Chelativorans sp. BNC1]
1
MDVVVVESPAKAKTINKYLGKDYKVLASFGHVRDLPAKDGSVRPEEDFAMSWEVDSPSAKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLRQKRALKDKPVRRVVFNAITKKAILDAMASPREVDASLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDLEAEIERFVREDYWQIAALLDTPRGDSFEARLTTLDGKRLQKLDIKSQEEADSIKALLDGAAYRVLSVEAKPTRRNPGPPFTTSTLQQAASSRLSFSASRTMQVAQRLYEGVEIGGETTGLITYMRTDGVQMAPEAIEAARSAVSNTFGPRYLPEKPRHYSSKAKNAQEAHEAIRPTDFSRTPDEVRKYLDSDQARLYEMIWKRAIASQMEAAEIERTTVEIEASGAGRAAGLRAVGSVVRFDGFLAAYAEVKDEDSQDEEDRRLPEINSGEALKRNSVNVTKHTTEPPPRYSEASLIKKLEELGIGRPSTYAAILKTLDDRGYVSNERRKLVPQAKGRIVTAFLENFFRRYVEYDFTADLEEKLDEISDGKLSWKQVLRDFWKDFSAAVGDIKELRVTDVLDALNEELAPLVFPTREDGGDPRICPKCGAGKLSLKLGRYGAFVGCSNYPECDYTRQLGENPAENGEAEAGLNGNKVLGTDPFTGEEITLRSGRFGPYVQRGEGKDAKRAGLPKGWTPEDLDHEKAIALLSLPRDVGKHPETGKMISAGIGRYGPFLLHDGTYANLETVEDVFSVGLNRAVSLLAEKQAKTNGARAKPAALKELGEHPDGGVITVRDGRFGPYVNVGKVNATLPKGKDPMSLTREEALELLAAKAGKTGKKPAKSKARS
(1004) DNA topoisomerase 1 [Azorhizobium caulinodans ORS 571]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATDPDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTAAFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATRNAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTADIIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRDFWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSGGEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPEDGEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFGPYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKKTAKAKADAAAEE
(183) DNA topoisomerase 1 [Starkeya novella DSM 506]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHVRDLPAKDGSVDPEHDFHMLWDIDPKAQKRLSDIARAVKGADGLILATDPDREGEAISWHVLEILKEKRALKDQPISRVVFNAITKQAVLDAMAHPRTIDAALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIETFVKREYWSIAATLATPRNETFEARLVGADGKKITRLDVGTEAEATDFRKALESADFKVRSVEAKPARRHPYPPFTTSTLQQEASRKLGLAPAVTMRIAQRLYEGVDVGGETVGLITYMRTDGVDMAPEAVAQARSVIGRDYGDRYVPNAPRKYTAKAKNAQEAHEAVRPTDLSRRPKDVSRHLEPEQAKLYELIWLRTVASQMESAELERTTVDIDAKAAGRALELRATGQVVKFDGFLTLYREGIDDGDEDEENRRLPAMSTGEALANKGIKADQHFTEPPPRYSEASLVKRMEELGIGRPSTYASVLAVLRDREYVKLDKRRLVPEDKGRLVTAFLESFFDRYVEYDFTADLEEKLDLISNGELAWKDVLRDFWRDFTAAVGETKELRVSDVISALDEMLTAHIFPPKEDGSDPRICPTCGTGRLSLKVGKFGAFIGCSNYPECKYTRPLAVQNGDSDNPAEANGTRVLGTDPVSGLEVTVRDGRFGAYLQLGEAKDGEKPKRSSLPKGLAPADVDLETGLALLSLPREIGVHPDNGEPILAGIGRFGPYVQHGRTYANLEAGDDVLSIGLNRAVALIADKQNKGPGRGRGAVGGRELGEHPTLGGQVTVRPGRFGAYVNHGKVNATLPKSMPAESVTLEQAVELITAKAGSAPAKPARRAAAKTASGDKPAKKAAPKKAAAKKSPAKKSG
(1057) DNA topoisomerase 1 [Candidatus Liberibacter solanacearum CLso-ZC1]
1
MNVIIVESPAKAKTISKYLGPDYKVLSSFGHVRDLPAKKGSVLPEKNFEMLWETDKSSQKHLENIISAVKSSTLLILATDPDREGEAISWHVLDILRQRNLIGERKIKRVSFNAITKKVVLNAMENTRDLNLDLVNAYLARRALDYLVGFNLSPILWRKLPGARSAGRVQSVALRLICHRENQIECFVSEEYWLLSVLLETPRGDKFIARLVDFNGQRIEKTSIGNKKEADKLISFLEKATYIVKNTETKPIKRNPWPAFTTSTLQQAASSRLGFSPSYTMRIAQKLYEGIDVNGEVVGLITYMRTDSVHLSLDALEEVRRSISSNFGNSYLPDKPRIYSVKAKNAQEAHEAIRPNDFNFLPSEMKKFLDSDQFQLYNLIWKRSVASQMASAEFERTTISIDATYEDQIAHLRTVGSCLRFDGFLKVWENQNDQENNSDEDKLLPCINKNEKLLAKETNASQHFTEAPLRYSESSLIKKMEELGIGRPSTYAAILETLSKRRYIVIEKRKLFPQNTGRIVTAFLENFFSRYVEYDFTADLEEKLDKISSGKLDWKEVLHEFWKEFIEKIDSTKELRTSNVLDILNDTLSSVIFPAKDNNEDSRTCPSCQKNPLSIKLSSKYGAFVGCTNYPECKYTRQLTTSNQQYIEENLEPLLLGDDPETKEPITLRSGRFGFYVQRGDGKDAKRCGLPKNWDRESIDYDKALSLISLPREIGIHPETQKSIIASMGKYGCYLKHDGHHTKLESIEQVLTINLDQAISCMIQKNKKEKSSRTSTKNQGHVIGIHPEGGSITIHRGRYGPYLNWGKINASIPNNENPDTIDLENALKIFETKIKGKKKS
(1309) DNA topoisomerase 1 [Bartonella clarridgeiae 73]
1
MNIVIVESPAKAKTINKYLGSQYKVIASFGHVRDLSAKDGSVLPDKDFAMKWDIDTASAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDILKQKKVLNNKPIKRVVFNAITKKSVLAAMKNPRDIDISLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICNRESEIEQFIKEDYWSITTYLKTLQDNIFYARLTEFNHKKLGKLDIRSQEQADQIFFMLEKANYRTLSIEAKPIKKNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVEINGETAGLITYMRTDGVQMASEAIDAARKAIIDSFGNHYVPEKPRFYSTKAKNAQEAHEAIRPTDFKRHPNQICNVLDSDQAKLYELIWKRAIASQMRSAEIERTTVEIEAFQEENHANLRAIGSVIHFDGFISAYTDPKEEENSEEDESTRLPQINIGESLKKEKVELTQHTTEPPPRYSESALIKKLEELGIGRPSTYASTLSTLCDRGYIITDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTANLEEKLDLISDGKLSWKDVLHDFWDEFNASITSIQELRIMNVLDVLNVTLAPLAFPTREDGSDCRSCPLCINGQLSLKLGRYGAFVGCSNYPECKYTCQLGTDTKEKSKVVHNDEPIMLGIDPETGKDISLRNGRFGPYIQLGEDKKSKRASLPKGWQIENINFDKALALLSLPREVGTHPETGKIITAAIGRYGPYLAHDGKYANLFSIDEVFDIGINRAITILAEKKNNETNRRRILPTVLTTLGDHPEGGTITIRDGRYGPYVNWNKINATLPRDKDPTTVTLSEALELISAKASTKKTGQKATSKKKLTPKKASPRKEKA
(494) DNA topoisomerase 1 [Bartonella bacilliformis KC583]
1
MDIVIVESPAKAKTINKYLGSQYKVIASFGHVRDLSAKDGSVLPDKDFSMKWDVDTASAKRLNEIAKAVKEANSLILATDPDREGEAISWHILDVLNQKKILNDKPVKRVVFNAITKQSVLDAMNNPRDIDVSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEREHFVKEDYWSITTYLKTPRNDVFQARLIEFNQKKLSKLDIQSQEQANQIRLMLEEAEYCTLSVEAKPTKRNPSPPFTTSTLQQASSSKLGFSASRTMQIAQKLYEGVEMNGETAGLITYMRTDGVQIAPEAIDSARRAISNSFGNNYLPEKPRFYSTKAKNAQEAHEAIRPTDFKRHPDQVRNFLDNDQAKLYELIWKRAIASQMRSAEIERTTVEIKAVQEENYANLRATGSVTRFDGFIAVYTDQRDETNGDEDDLARLPPINVNEILTKEKIETAQHTTDPPPRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIIIDKRQLTPDAKGRIVTAFLENFFNRYVEYGFTANLEEKLDLISDGKLFWKDVLRDFWDEFNASVTNIQELRITNVLDVLNTTLAPLAFPTREDSSDPRSCSLCKHGQLSLKLGRYGAFVGCSNYPECKYTKQLGTDAGEEREAAHNDEPVILGVDPETGKDIFLRNGRFGPYIQLGEGKEAKRSGLPKGWKTENVNLDKALSLLSLPREVGIHPETGQMITATIGRYGPYLTHDRKYAALSNVDDVFDIGINRAVTVLAEQKENKANRGKTVSSVLAALGDHPDGGSITVRDGRYGSYVNWGKINATLPKDKDPANITLSEALELLSAKTSAPSKTRKVAAKKTAPKKNTTVKKASSTIKKAK
(38) DNA topoisomerase 1 [Bartonella tribocorum CIP 105476]
1
MNIVIVESPAKAKTINKYLGPQYKVVASFGHVRDLPAKDGSVLPDQDFSMKWDIDSAAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPIKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTQLKTIRNDHFQARLTMFNQRKIGKLDIQSQEQADQIRLMLEKAQYHTLSVEAKPTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGEVAGLITYMRTDGVQIAPEAIDAARKVIHESFGKDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRSPNQVRNFLDDDQAKLYELIWKRAIASQMCSAEIERTTVEIEAQQGDNRANLRATGSVVRFDGFISVYTDQRDEENNEENETTRLPQINTGEALTKEKVESLQHTTEPPSRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIVIDKRKLIPDAKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNTSISNIQELRIANVLDVLNVTLAPLAFPEREDGSDVRSCPLCKNGQLSLKLGRYGAFVGCSNYPECRYTRQLGTTDTEEENEAVRNDEPVMLGIDPETGKDISLRNGRFGPYIQRGESKEVKRAGLPKEWQAENITLERALALLSLPREIGIHPETGKMITATIGRYGPYLSHNGKSARLLHADEVFDIGINRAVTVLAEQQENKTKQSRTTSAALATLGEHPEGGTVTVRNGRYGPYVNWGKINATLPKEKDPISVTLSEALELISAKASSKKAISKRASSKTKAKTKET
(155) DNA topoisomerase 1 [Bartonella quintana str. Toulouse]
1
MNIVIVESPAKAKTINKYLGSQYKVLASFGHVRDLPAKDGSVLPDQDFSMKWDVDSAASKRLNEIAKAVKEADSLILATDPDREGEAISWHILDILRQKKVLKDKPVKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTDLKTIRNEGFQARLTMFNHKKIGKLDIQSQEQADQMRHMLESAKYHTLSVEAKHTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGVEINGEMAGLITYMRTDGVQIAPEAIDSARKVIHEFFGSDYVPEKPRFYSTKAKNTQEAHEAIRPTDFQRIPNQVRNFLDTDQVKLYELIWKRAIASQMRSAEIERTTVEIEAQQGENHANLRATGSVIRFDGFISVYTDQRDEENSEENEITHLPQINTGETLTKEKVEAIQHSTEPPPRYSEASLIKKLEELGIGRPSTYASTLATLSDRGYIIIDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRNFWDGFNASITNIQELRITNVLDVLNITLAPLIFPGREDGNNVRSCPLCSSGQLSLKLGRYGAFVGCSNYPECKYTRQLGTDPGEEKEVMRNDEPVMLGIDPKTGKDVSLRNGRFGPYIQVGEQKEAKRVRLPKEWQTEKMTLDKALALISLPREIGIHPETGKIITATIGRYGPYLAHDGKYAPLLHADEIFDIGINRAVTVLAEKQENKTKRNRTKTAALATLGDHPDGGTVTIRNGRYGPYVNWGKINATLPKDKDPISVKLSEALELISDKASSKKTTAKKASSKRKET
(1356) DNA topoisomerase 1 [Wolbachia endosymbiont of Drosophila melanogaster]
1
MALLIVESPAKAKTIGKYLSKEFKVAASFGHVRDLPAKNGSVDPDNDFTIKYETIEKAEKYIKELVKAASKTSDIYLATDPDREGEAMAWHVIETLKEKKAISNENNIYRVVFNEITKRAVQEAIKNPREINMDLVRAQQARRALDYLVGFSLSPLLWTKLSGSKSAGRVQSVALKIICEREDEISKFITQEYWSIKAEMQNSKDEAFFAMLSHYDNKKLEKFDIKNEEEAKNLVREIESRQYAVSTVERKQVKRNPLPPFITSSLQQDAVNKLYFNVKSVMRIAQNLYEGIDIGGETVGLITYMRTDGFHIADEAINSIRGSIKSLYGDKYLPQSPRKYVKKVKNAQEAHEAIRPTDINRTPGSIKDYLTPEQFKLYDLIWKRTIASQMESAILDQVVVEISSTDQKVILRASGSSIFFDGFYRVYQDNIEAENEGLLPAMKEGEACKLISVEPKQHFTQPPPRYSEASIVKKMEEIGIGRPSTYATIISVLQDREYVSLDSKRFIPSSRGKIVTIFLETFFQRCVEYDFTAQMEEKLDLISNGHADWKKELGHFWVPFFGHVNSVKQMTHDEVFSGIHDLVIDWFCSEEGRKEVNTKCPACLGGILKLNFGKAGVFLGCSNYPECNHTKEITGSNDNSEYPKSLGIDDITNQEVMIKKGPFGLYLEFNNELKKKKTVSIPKDINVNEIDLSTATQLLSLPKVIGEHPETGKEVKIGLGRFGYYIFYDGRYFSLKKSSKEVLNTELSEAVQIIANSPRKELKSLGVNEKGKEVFICNGRYGFYIKCGKTNVALGKSADIESIDLEKALELIKGKK
(496) DNA topoisomerase 1 [Rickettsia japonica YH]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPNENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRIAFNEITKKAIIHAVENPRKLDNNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTEKLKSQKFHVDKIEKKQQKRQPQPPFITASLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAQANGSTIAFDGFYKVYRESMDDKAEEANKMLPPLKEQEPLKTKKVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKVCPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGEQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGKFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKPA
(1592) DNA topoisomerase 1 [Ehrlichia ruminantium str. Welgevonden]
1
MSLIIVESPSKAKTIGKYLGSKYKVVASFGHIRDFPAKSGSVDPDKDFAMTYEIIAKSEKYVSKLVQVANKETKEIYLATDPDREGEAIAWHIVEVLREKNAINNNIVINRMVFNEITKNAILASVKNPRNINMDLVYAQQARRALDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLICDRENEIEKFITQEYWDIEAKLQNVEGREFSAYLKCYSGNKLEKFDIKNEEDANRLSAEIRQRSYSVSSVEKKHTKRNPYPPFITSSLQQEASTKLGFSAKSTMLIAQKLYEGVDIGGEIVGLITYMRTDGVYISDEAVEHIRSVISSMFGKEYLPESPRKYVKKIKNAQEAHEAIRPTNITITPDSLVSYLTQEQLKLYDLIWKRTVASQMNSAVLDQVIVELSSLDGIVILRALGSSLSFDGFYKVYGHDDDSKNSILPLLNENDHCPLNDVIPNQHFTNPPARYSEASLVKKMEEIGIGRPSTYASIISVLQDRQYVVLNQKRFFPTERGRVVNIFLVNFFNRYVEYDFTADLEEKLDLISNGKIGWKEVLHQFWFLFIDNVNSVKKLEFTQILNAISSEMESHIFPSDVSEVDKMCPVCNVGTLSLNISKNGVFLGCSQYPECKYTKNIGDSTVDNTEVSQYPRVLGSDAASGEDIYLKKGPYGIYLQIGSGKDGKRATLPKDIDLNLLDLEMAKKILSLPISLGMYPDTNSEIKLGLGKFGAYIFYEGKYFSIKKFEGNFLDITLENAIAIIQKNRTNGVIKSLGMSQDNKEVFLCKGRYGFYLKYDKLNIAIKKGIDVEQMSLVDALKLISEKL
(1593) DNA topoisomerase 1 [Ehrlichia ruminantium str. Welgevonden]
1
MSLIIVESPSKAKTIGKYLGSKYKVVASFGHIRDFPAKSGSVDPDKDFAMTYEIIAKSEKYVSKLVQVANKETKEIYLATDPDREGEAIAWHIVEVLREKNAINNNIVINRMVFNEITKNAILASVKNPRNINMDLVYAQQARRALDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLICDRENEIEKFITQEYWDIEAKLQNVEGREFSAYLKCYSGNKLEKFDIKNEEDANRLSAEIRQRSYSVSSVEKKHTKRNPYPPFITSSLQQEASTKLGFSAKSTMLIAQKLYEGVDIGGEIVGLITYMRTDGVYISDEAVEHIRSVISSMFGKEYLPESPRKYVKKIKNAQEAHEAIRPTNITITPDSLVSYLTQEQLKLYDLIWKRTVASQMNSAVLDQVIVELSSLDGIVILRALGSSLSFDGFYKVYGHDDDSKNSILPLLNENDHCPLNDVIPNQHFTNPPARYSEASLVKKMEEIGIGRPSTYASIISVLQDRQYVVLNQKRFFPTERGRVVNIFLVNFFNRYVEYDFTADLEEKLDLISNGKIGWKEVLHQFWFLFIDNVNSVKKLEFTQILNAISSEMESHIFPSDVSEVDKMCPVCNVGTLSLNISKNGVFLGCSQYPECKYTKNIGDSTVDNTEVSQYPRVLGSDAASGEDIYLKKGPYGIYLQIGSGKDGKRATLPKDIDLNLLDLEMAKKILSLPISLGMYPDTNSEIKLGLGKFGAYIFYEGKYFSIKKFEGNFLDITLENAIAIIQKNRTNGVIKSLGMSQDNKEVFLCKGRYGFYLKYDKLNIAIKKGIDVEQMSLVDALKLISEKL
(794) DNA topoisomerase 1 [Rickettsia bellii RML369-C]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVIPDENFSMKYDISEKAGKYVDAIIKDAKKAESVYLATDPDREGESISWHIAEVIKEKNKVKSDDFFKRVAFNEITKKAITHAIENPRKLDNNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMLNSNNELFTAKLTHINDQKLEKFSITNDKEAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAVDEIRKLINKDYGDKYLPSSPRIYKSKVKNAQEAHEAIRPTNINYIPNDLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVNATLASENKEYLARANGSTIAFDGFYKVYRESIDDEAEEENKMLPPLKEQEHLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYATILSVLQDRKYVTLEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKSALGNFWNGFNHNIESVNKQNITEIISYVQQALDYHIFGENKDSKVCPSCKTGELSLKLGKFGAFLACSNYPECNFRKSIVSGNDNNEADGEAKDIVNENKVLGKDKEGIEIYLKKGPYGPYIQYGEQVDSKIKPKRSPLPAGLNQNDITLDMALKLLSLPLKIGNHKESGEEVLVGYGKFGPYIKYMGKFISIPKKYDFLNLSLDDAMKLIEEKLNAIAAKQPNPLNMDEVTNLVDKKIKVKKTKK
(932) DNA topoisomerase 1 [Rickettsia typhi str. Wilmington]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDKNFAMEYDISDKASKYVDAIVKYARKAEAVYLATDPDREGESISWHVAEVIKEKNKVESDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICDREDEIERFKAEEYWDISLKMQNSNNELFTAKLTHVNDQKLKKFSIINEKEAKDLTRKLKLQKFYVEKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGNKYLPINPRIYQSKVKNAQEAHEAIRPTNITYTPDNLKQKLEKDYYKLYELIWQRTIACQMENVIMDLVIANLASENKEYLAKANGSIIAFDGFYKVYRESLDDEDEEDNKMLPPLKAQEHIKTKEVIPNKHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVTLEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKTSLNNFWSGFNNNIESVNEQKITEIINYLQKALDYHLFGENKESKVCPSCKTGQLSLKLGKFGAFLACSNYPECTFKKSIVSGNDNNEDEGNLSTILNDNKILGTDKDGVEIYLKTGPYGPYIQLGEQCGKVKPKRTPVPTNLKQSEITLEVALKLLSLPLKIGIHKDSGEEIIIGYSKFGPYIKYMCKFISVPKKYDFLNLNLDDAIKLIENNKAKLEKKHRSMV
(1052) DNA topoisomerase 1 [Orientia tsutsugamushi str. Ikeda]
1
MKLLIVESPAKAKTINKYLGSDFQVVASYGHVRDLLAKAGSVLPEQDFLIKYEINPKSTRHIKTICDLAKKSECIYLATDPDREGESISWHIVEVLKEKKIFANFKRIIFNEITKKAIGDALQQPRDINLNLVNAQQARRSLDYLVGFSLSPLLWRKLPGCKSAGRVQSVGLRLICEREEEISKFISQEYWNIHIDMISNKDEIVTAKLIEFDGNKLEKFSITNQSQAQDIVKNIENQQFKVIDITRKQRKKSPPPPFITSSLQQEAAGKLGFTAKKTMTIAQKLYEGIDLNNESTALITYMRTDSVMLSKDFIDETRNFISSSFGSNYLPKQIRAFKSKVKNAQEAHEAIRPININLTPELLLNKIEKDYLKLYELIWQRTVACQMENVILNLESINFASFNQLHVAKATGSTIAFDGFYKVYKEINDEEENKKLLPNLSQNEVMQVKNILPKQHFTEPPPRYSEATLVKTLEDLGIGRPSTYATIISVLQERDYVILDQKRFIPQNKGRLVTAFLTAFFKKYVEYDFTAKLEDQLDSIAKGMIEWQEILKNFWTGFNNNVQEIEQYKITDIIPQIETLLSNFLFPAQNDETDHKLCTLCKVGKLSLKLSKYGAFLACDNYPSCNFTRNIAAAFENNDNLPKGKNNKAIGYSDDMQKTIYLKEGPFGWYIQAGEDSTNKNDKPKRVPISVISSSPQDITLETAVKLLALPKVIGLNPNTNKEITVAVGRYGPYLKHDGKFISIPKNYDYLNLSINDCIKIITSSSSQLRKAKKDAPTNSDKVAKSKS
(508) DNA topoisomerase 1 [Anaplasma centrale str. Israel]
1
MMGVVIVESPSKAKTISKYLGGKYKVVASFGHVRDFPAKSGSVDPDDDFRMIYEIIPKSEKYIDKIVKAVSSEKSGIYLATDPDREGEAIAWHIIEVLRERSAIGGDVAINRMVFNEVTKRAVTAAISDCRSINMDLVHAQQARRVLDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLVCEREHEIERFDSKEYWNIEVLLKSKSGEELTAALKCYNGEKLDKFAIPNADSASAIAEHVRNGTYHVASVEAKRTKRNPHPPFITSSLQQEASTKLGFSAKNTMMVAQKLYEGIDIGGETVGLITYMRTDGFYISSEAISYIRDTIKMQFGEQYLTKSPRKYVKKVKNAQEAHEAIRPTDITMTPDSLAQYLSEDQLKLYDLIWRRTMASQMESAVIDQVIVDIQSKDGSVVLHAVGSSLGFDGYQRVYGTDDDDKRKMLPKLEAGEDCSLVEVSPSQHFTQPPPRYSEASLVKKMEEIGIGRPSTYATIISVLQERGYTQLEQKKFVPSERGRIVNAFLTNFFGRYVEYDFTANLEEELDLISNGNMAWKEVLRRFWDKFISDVSTVKGIEVSEILKSITKDLEEYAFSPNAGEAVNRSCPGCGEGELMLNIGKYKAFLGCNRYPECKYTRGVGGDSGVCRDEFPKVLGLDDATQEEIILKHGPYGEYLQLGDNAKGKRVAVPQGIQEITLDVAKKLLSLPITLGHYPNTAQDVKLGTGRFGPYVLYGGTYFSVKGREDFWNLTFEEAVNVIDSQAQKKSKLLGLHDNGKEIYVCKGRYGFYLKCDKKNVAIKGKGGDITLEDAVSLLNQKP
(534) DNA topoisomerase 1 [Anaplasma phagocytophilum str. HZ]
1
MGVVIVESPSKAKTISKYLGKKFNVIASFGHIRDFPAKSGSVDPSNDFKMIYEIIPKSEKHLDKIVKTVSAEKEAIYLATDPDREGEAIAWHIVEVLKEKCAIAKDVTVNRMVFNEVTKRAVTAAVDNCRPINMDLVRAQQTRRVLDYLVGFTLSPLLWRKLPGSRSAGRVQSVALRLLCEREYEVEQFKTQEYWDVGVDLQNQGGEKFEAVLKCYAGEKLEKFSIGTEEQAKEYAETVKNQSYTVESVESKKTKRNPYPPFITSSLQQEASTKLGFSAKNTMMIAQKLYEGIDIGGEIVGLITYMRTDGFYISEDAVNYIRDTIKMQFGEKYLSKSVRNYTKKVKNAQEAHEAIRPTDITMLPEQLSKYLTDEQLKLYTLIWKRTLATQMESAVIDQVAVDIKSSCGKISLHATGSTLSFDGYYRVYGSEDSDKRRMLPQLREGESCELLEVHPNQHFTQPPARYSEASLVKKMEEIGIGRPSTYATIISVLQERGYTQLEQKRFIPSERGRIVNAFLTNFFRKYVEYDFTANLEEELDLISNGKMVWKEVLSQFWDKFISDVSSVKTIEASEILKAITRDLENYAFSSVDGESISRVCPQCGSGELMLNIGKTSAFLGCNRYPECRYTRGIGGDGSASPADDASRILGIDEETQEEIFLKRGPYGEYLQLGNSTKRVSLTKSAGEITVDLAKKMLSLPLVLGCYPDTDKEIKLGIGRFGPYLFYNGVYFSIKDREDYINISHQEAVEIIDKQSDKKAKLLGQNKDGKDIYVCKGRYGFYLKCDKTSVALKGRSEDITLEDAILLLSQKQ
(1552) DNA topoisomerase 1 [Ehrlichia canis str. Jake]
1
MSLIIVESPSKAKTIGKYLGSKYKVVASFGHIRDFPAKSGSVNPDKDFAMTYEIISKSEKYVNKLIQVASKETHGIYLATDPDREGEAIAWHIVEVLKENNAIDDNVVINRMVFNEVTKNAILESIKHPRSINMDLVYAQQARRALDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLICDRESDIEKFVTQEYWDIEAKCQNVEGKQFSAFLSYYAGKKLEKFDIKNEEDAKRLAEEVKSRNYSVVKVEKKHTKRNPYPPFITSSLQQEASTKLGFTAKNTMLIAQKLYEGIDVGGEIVGLITYMRTDGFYIADEALDHIRSIIVSIFGKEYLPASARKYVKKVKNAQEAHEAIRPTNITITPDSLSNYLTPEQLKLYDLIWKRTVASQMNSAIIDQVVVELASSDKVVTLRATGSSLFFDGFYKVYGHNEDDDNKNNMLPLLQVSDECPLNEVIPHQHFTIPPARYNEASLVKKMEEIGIGRPSTYASIISVLQDRQYVILNQKKFFPTERGRIVNIFLVNFFSRYVEYDFTADLEEELDLISNGKINWKKVLHKFWFLFIDNVNSVKKLEFTEILKVISCEMENYIFSSDKSETGRVCPACNDGTLGLNISKNGIFLGCSGYPECKYTKNVGGDLVDDVDNVQYPKVLGIDTATCQEIYLKKGPYGVYLQIGSDKNGKRAAIPKNMNANLLDLQMAEKILNLPISLGTHPETCKEIKLGLGKFGAYILYEGKYFSIKNESNFLDVKLEDAIDIIANSSTNGVIRSLGISEDNKEVLLCKGRYGFYLKYDKLNVALKKGTDVEQMSLSDAMKLISEKK
(1230) DNA topoisomerase 1 [Wolbachia endosymbiont strain TRS of Brugia malayi]
1
MALLIVESPAKARTISKYLSKEFKVAASFGHVRDLPVKNGSVDPDNDFAIKYEIIEKAEKYVKELVKEASQTSDIYLATDPDREGEAIAWNVIEALKERKAINDKSNIYRVVFNEITKRAVQEAVKNPREINMDLVRAQQARRALDYLVGFSLSPLLWTKLSGSKSAGRVQSVALKLICEREDEISKFVSQEYWSIRAEIKDSKGETFFAMLSHYDNKKLEKFDIKNEEEAKGLVKQIESRQYAVSTVERKQVKRNPLPPFITSSLQQDAVNKLYFNVKNVMRIAQDLYEGIDIGGETVGLITYMRTDGFYIADEAVNSIRRSIKSLYGNKYLPKSSRQYVKKVKNAQEAHEAIRPTDIDRTPDSIKDYLTPEQFKLYGLIWKRTIASQMESAILDQVVVEISSTDQKVILRASGSIIFFDGFYKVYKNNVDGEDESMIPTMKEGEECKLISVDPEQHFTQPPSRYSEASIVKKMEEIGIGRPSTYAAIISVLQDREYVTLDNKRFIPSSRGKIVTIFLETFFQRCVEYDFTAQMEEKLDLISNGRADWKKELGYFWVPFFNHVNSVKQMTHDEIFNGIRDLVVDWFCSEEGKKEVNKKCPDCPDGILKLNFGKAGVFLGCSNYPTCTHTKEITGSNDNSEYPKSLGIDGVTEQEVVIKKGPFGLYLEFNSESEKKKTVSIPKDINVNDIDLSTATRLLSLPKVIGEHPETGKEVKIGLGRFGYYIFYDSKYFSLKKSFKEVLEIQLDEAVQIIANSPRKELKSLGFNEKGKEVFICNGRYGFYIKCGKTNVALGKNADIESVDLRRALELIKSKK
(23) DNA topoisomerase 1 [Bradyrhizobium japonicum USDA 6]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDANFKMIWEVDPKAAGRLNDIAKSLKGADRLILATDPDREGEAISWHVLEVLKEKRALKDQKIERVVFNAITKQAVTDAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLIATLLTPRGDAFEARLVGADGKKIQRLDVGSGAEAEDFKKALEAAAYAVTAVDAKPARRNPQAPFTTSTLQQEASRKYGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDPSAITQARKVIGEDYGNAYVPEAPRQYQAKAKNAQEAHEAIRPTDMSRRPDSMSRKLDADQARLYELIWKRTIASQMESAELERTTVDITAKAGSRTLELRATGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSPNDALKRQSLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLHGEDKGRVVVAFLESFFNRYVEYDFTANLEEQLDRISNNEISWQQVLKDFWTGFIGAVDEIKDLRVAQVLDVLDDMLGQHIYPPRADGGDIRQCPSCGNGRLNLKAGKFGAFVGCSNYPECRYTRQLAADSETTADRSLGQDPDTGRDVWVKAGRFGPYIQLGEPKDYEEGEKPKRAGIPKGTSPGDVELELALKLLSLPREIGKHPETGQPITAGLGRFGPFVKHEKTYASLESGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKAIGDHPTLGTVTVKSGRYGAYVTAGGVNATIPAEFEKDTVTLPQAIALIDERAAKGGGKTKAKKAAKPAKAKKAAEKAADGDDAAPKPKKPAAKKAAKPKSESTSKARAAVSSTAKTSPTKAAAPKAPAKKSAGKT
(942) DNA topoisomerase 1 [Bradyrhizobium sp. ORS 278]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPEENFRMIWEVDPKAAGRLNDIAKSLKGADRLILATDPDREGEAISWHVLEVMKEKRALKDQKIERVVFNAITKQAVSEAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLIATLATPRGDTFEARLVGADGKKIQRLDIGTGAEAEDFKNALNAATYSVATVDAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIAPEAITQARKVIGEIYGNKYVPDSPRQYQTKAKNAQEAHEAIRPTDLSRKPAELRKRLDDDQAKLYELIWTRTIASQMESAELERTTVDIVAKAGGRTLELRATGQVIKFDGFLALYQEGRDDEEDEDSRRLPQMSQGEALKRQNLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILDVLKARGYVKLEKKRLHGEDKGRVVIAFLENFFRRYVEYDFTADLEEQLDRISNNEIAWQQVLKDFWTGFIGAVDDIKDLRVAQVLDALDEMLGPHIYPPREDGGDVRQCPTCGTGRLNLKAGKFGAFVGCSNYPECRYTRPLAADSEAAADRMLGQDPDSGLEVAVKAGRFGPYIQLGEQKDYAEGEKPKRAGIPKGTQPSDVDLDLALKLLSLPREIGKHPETGLPITAGLGRFGPFVKHDKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSKRFGADPGKALGDHPSLGPVAVKAGRYGAYVTAGGVNATIPGDKEKDTITLAEAIALIDERAAKGGGKAKAPKKAAKPKAAAKPKAGGDDDTPKPAKKAVAKKAAAKPKSDSTSKARAPVAKAAKTSAKPATKATPKKSAGKARG
(1368) DNA topoisomerase 1 [Bradyrhizobium diazoefficiens USDA 110]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDANFKMIWEVDPKAAGRLNDIAKSLKNADRLILATDPDREGEAISWHVLEVLKEKRALKDQKIERVVFNAITKQAVTDAMKHPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVAREYWSLVATLLTPRGDAFEARLVGADGKKIQRLDIGTGAEAENFKKALEAAAYAVTAVDAKPARRNPQAPFTTSTLQQEASRKYGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDPSAITQARKVIGEDYGNAYVPEAPRQYQAKAKNAQEAHEAIRPTDMSRRPDSMSRKLDSDQARLYELIWKRTIASQMEAAELERTTVDITAKAGGRTLELRATGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSAGDGLKRQSLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLHGEDKGRVVVAFLESFFSRYVEYDFTANLEEQLDRISNNEISWQQVLKDFWNGFIGAVDEIKDLRVAQVLDVLDDMLGQHIYPPRADGGDIRQCPSCGNGRLNLKAGKFGAFVGCSNYPECRYTRQLAADSEATADRSLGQDPDTGRDVWVKAGRFGPYIQLGEQKDYEEGEKPKRAGIPKGTSPGDVELELALKLLSLPREIGKHPETGQPITAGLGRFGPFVKHEKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKAIGDHPTLGTVTVKSGRYGAICHRRRRQRDDPGRVRKGHRHAAAGDRTD
(280) DNA topoisomerase 1 [Nitrobacter hamburgensis X14]
1
MFAPKPSAHLSRNRPRVFPLSYWNNMNIVIVESPAKAKTINKYLGASYEVLASFGHVRDLPAKNGSVDPDANFQMIWEVDPKAVGRLNDIAKSLKGADKLILATDPDREGEAISWHVLEVLKQKRALKDQKIERVVFNAITKQAVTDAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCSREIEIEKFVPREYWSLIATLATPRGDTFEARLVGADGKKIQRLDIGSGAEAEDFRKAIEAANFIVSTVEAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDGSAITQARKVIGEDYGNAYVPDAPRQYQTKAKNAQEAHEAIRPTDLSRRPADMKRRLDADQARLYELIWIRTIASQMESAELERTTVDIAARAGSRVLELRASGQVIKFDGFLALYQEGRDDEEDEDSRRLPAMSDGEALRRENLSVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLYGEDKGRVVVAFLENFFARYVEYDFTANLEEQLDRISNNEVSWQQVLKDFWNDFIGVVNEIKDVRVSEVLDVLDNMLGPHIYAPREDGGDPRQCPTCGTGKLNLKAGKFGAFVGCSNYPECRYTRPLAADGEAGGDRILGKDPESGLDVTVKSGRFGPYIQLGEPSDYGEGEKPKRAGIPKNTSPADMELDLAVKLLSLPREIGKHPETGEPITAGIGRFGPFVRHEKTYASLEAGDEVFDIGLNRAVTLIAEKIAKGPSRRFGADPGKPLGEHPTLGSVAVKSGRYGAYVTAGGVNATIPSDKTQDTITLPEAIALIDERAAKGGGKPKRAAKKAKSAGTERTGKAGAVAAKPAKKAAAKQASVKPKSAAVSKARGSIAAVKPPAKAEKAPAKKSAGKNG
(1115) DNA topoisomerase 1 [Polymorphum gilvum SL003B-26A1]
1
MESPAKAKTINKYLGSGYQVLASYGHVRDLPAKDGSVKPDEDFAMSWEVDSKSQKRLNEIAAAVKDADRLILATDPDREGEAISWHVLEVLHKKRVLKDKPVERVVFNAITKQAILEAMKHPRAIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLICDREMEIETFVKEEYWSILANLKTPSAEVLQAGLTGFDGRKIGRLDIKTGDEAETIRRMLEAARYTVASVVSKPAKRHPQPPFTTSTLQQEASRKLGFAAARTMQVAQKLYEGVAIGGETTGLITYMRTDGVQIAGEAISATRKVIGQDFGDNYVPEKPRFYSSKAKNAQEAHEAIRPTDLARRPRDVARFLDPDQARLYELIWKRTMASQMESAVLERTTIDIDAAGAGKTATLRATGSVVRFDGFLALYQEGRDDEEDEAARRLPAVDDGAPLALAAVEGKPSAIEADQHFTTPPPRYTEASLVKKMEELGIGRPSTYASTLQTLRDRDYVAFDKKQLVPQDKGRIVTAFLESFFNRYVEYDFTASLEEQLDRISAGELSWREVLANFWRDFSASVDETKDLRVSQVIDALNDLLAAHIFPPREDGKDPRACPTCATGQLSLKVSRFGAFIGCSNYPECSYTRQLARNGDGEGEDAASDGPKVLGTDPATGLEVSLRSGRFGPYVQLGEDAKPRRSSLPRGWSAADLDLARALQLLSLPRDVGAHPEDGKMITAGLGRYGPFVQHDGTYANLGSADEVFSVGLNRAVDLLAEKRSKTGRGRATPAALKELGEHPSAGGPITVRDGRYGPYVNWAKVNATLPKGSDPMAVTLEQAVELIAAKGGGKAAPKKAATKKPAAKKPAAAKKSASRTKAKAGGAAADGTS
(499) DNA topoisomerase 1 [Caulobacter crescentus CB15]
1
MNVVVVESPAKAKTINKYLGSDYTVLASYGHIRDLPSKDGSVEPDNDFAMSWEVDAKASKRVSDIVDAMKKADRLILATDPDREGEAISWHVLEVLNKKKALKDKTVQRVTFNAITKTAVTEAMKAPRDLDMELVEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLVVDRELEIERFKTQEYWTVDADVSAGSDPFLARLVKHEGKKLTKFDLGNETSALTAKAAVEAAVFKVEAVEKKPGKRSPAPPFTTSTLQQEAARKLGFSAQRTMQAAQKLYEGVDIGGETVGLITYMRTDGVSMAPEAIFEARDVIGAVYGKEYVPDSPRMYKSKAKNAQEAHEAIRPTAMGRNPGSLRLEPELGRLYELIWKRTIASQMESARIERTTVDLTSADGQTGLRATGQVVQFPGYLAVYEEGRDDEGDEDSARLPAITEGASAKVLKSRADQHFTEPPPRYSEASLVKKMEELGIGRPSTYASVLGVLRDREYVRMEKQRFIPEDKGRLVTAFLEQFFKRYVEYDFTAALEEKLDLVSDGKLDWKEFLREFWKDFHAAVGEIAELRTTNVLDALNEALGPHIFPDKGDGSNPRLCPTCGSGQLSLKTGKFGAFIGCSNYPECRYTRQLGVSEGDGDAESADKQLGLNPATGLAVWLKNGRFGPYVEELAAEGSSDKPKRSSLPKGWIASAMDMEKALRLLSLPREVGKHPDDGKVITAGLGRFGPFVLHDGTYANLENADEVFDVGLNRAVAILADKRAGGGRPQRGAAAALAELGNHPEDGKPIRVLSGRFGPYIKHGDTNANVPKGKDPAAITLEEALALIAERAAKGGAKKPAKKAAATKSKAKAESDAPAKKTAAKKPAAKKPAAKKAAPKAKAKATAASDDGAAPWDDEG
(1277) DNA topoisomerase 1 [Caulobacter segnis ATCC 21756]
1
MNVVVVESPAKAKTINKYLGSDYTVLASYGHIRDLPSKDGSVEPDNDFAMSWEVDAKASKRVSDIVDALKKADRLILATDPDREGEAISWHVLEVLNKKKALKDKSVQRVTFNAITKTAVTEAMKAPRDLDMELVEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLVVDREIEIERFKTQEYWTVEADVSAGSDPFLARLVKHEGKKLTKFDLGNETSALAAKAAVQAAVFKVEAVEKKPGKRSPAPPFTTSTLQQEAARKLGFSAQRTMQAAQKLYEGVDIGGETVGLITYMRTDGVSMAPEAITEARDVIGKVYGKEYVPDVPRLYKSKAKNAQEAHEAIRPTSMGRNPGSLRLDPELGRLYELIWKRTIASQMESARIERTTVDLESADGKTGLRATGQVVQFPGYLAVYEEGRDDEGDEDSARLPAIVEGSPAQVREARADQHFTEPPPRYSEASLVKKMEELGIGRPSTYASVLGVLRDREYVRMEKQRFIPEDKGRLVTAFLEQFFKRYVEYDFTAALEEQLDLVSDGKLDWKQFLRDFWKDFHAAVGEIAELRTTNVLDALNEALGPHIFPDKGDGSNPRLCPTCGTGQLSLKTGKFGAFIGCSNYPECRYTRQLGVSEGDGEAESADKELGVNPATGRAVWLKNGRFGPYVEELAAEGDKPKRSSLPKGWIASAIDLEKALRLLSLPREVGKHPDDGKVITAGLGRFGPFVLHDGTYANLENADEVFDVGLNRAVAILADKRAGGGRPQRGAAAALAELGNHPEDGKPIRVLSGRFGPYIKHGDTNANVPKGKDPAAITLEEALALIAERAAKGGGKKPAKKAAASKAKAPTKAEGDKPAKKTAAKKPAAKKTAPKAKAKAPAASDDGAAPWDDEA
(1848) DNA topoisomerase 1 [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]
1
MKLVVVESPAKAKTIEKYLGSGYQVLASYGHIRDLPSKDGSVNPDNGFSMVWQNYPDKAHRLKAIEDAVKESDSLILATDPDREGEAISWHILELLKTKKLLPDDVERVTFNAITKAAVTDAMAHPRQLDNDLINAYLARRALDYLVGFTLSPILWRKLPGAKSAGRVQSVALRLVVDREQEIEGFKPQEYWSVEADMEADSIGFTSRLIQWRGQKLEKLSIADKTQAEAAQSDVESGHFTVSNVETKPVSRNPQPPFTTSTLQQEAARKLGFAASHTMRLAQSLYEEGLITYMRTDGVQMDESAIAAARKTITQRYDGGYVPDKPRQYQVKAKNAQEAHEAIRPTDFSRDKAASGDHARLYELIWKRALASQMASAKLERTTVDLTDGTGQNVLRVTGQVVLFSGFLTLYEESADDNANDRDGKEGRARLPLLRAGDAPLKKEVRADQHFTQPPPRYSEASLVKKMEDLGIGRPSTYASVIQVLKDRAYVTLERNRFIPSEAGRLLTAFLERFFERYVSYDFTAGLEDSLDEISGGRADWQKVLDAFWHDFKPKTAEVMEQQPSAITAELDKFLEPWLFPDKGDGHDPRECPSCHTGRLALKGGRFGAFIACSNYPECKYTRGFGQGEDGVDDNEPVLLGYMPENSDDDGYMAFSDQGDILPANTASASETGVTDGGIAANAAFSGKGNSASHTDRDDLPFDPDEPASSTGNVASSQSRMTGDETASSGNSRDSSAHGVSTTAGIDAESQAGISNQALAGKNNAGRTAVSDNKGNNSSSTIAAARKGGSTDDNATVSDPDGDIGSGASSSGQDADNRLLSHRNGDIDSRAIPADHKDSSSDQNASHALSPDRNSDDASVSNSDKKIDSKAVSTGHDVGNAITSDNSPSDNVAHLASTPSSATSSVKVALETENNDTAASKADEQAKEEEESRKARAVTRRTGRFGPYIQLGEGKNAKRVSVPRDVNPREVDFSLASRLLALPREIGLHPESGKMIIAGTGRYGPYLNCDGKYARLSSTEELLDIDIDRAVVKLAEAAQNKGRTGATLSREPLKVFGDSPVTEKPVQLMNGRYGPYVTDGETNASLPKDTTPESLTFEEALALLEARAKMPKKKKTKKAAAKKPAAKKTTTKKAAPKKATTKTATPKSATTDNATSEDGDATPAKSPAKKAVAKKTTAKKPASKSATKKAPSSKTTAAKKTSKATPKDEVAE
(1847) DNA topoisomerase 1 [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]
1
MKLVVVESPAKAKTIEKYLGSGYQVLASYGHIRDLPSKDGSVNPDNGFSMVWQNYPDKAHRLKAIEDAVKESDSLILATDPDREGEAISWHILELLKTKKLLPDDVERVTFNAITKAAVTDAMAHPRQLDNDLINAYLARRALDYLVGFTLSPILWRKLPGAKSAGRVQSVALRLVVDREQEIEGFKPQEYWSVEADMEADSIGFTSRLIQWRGQKLEKLSIADKTQAEAAQSDVESGHFTVSNVETKPVSRNPQPPFTTSTLQQEAARKLGFAASHTMRLAQSLYEEGLITYMRTDGVQMDESAIAAARKTITQRYDGGYVPDKPRQYQVKAKNAQEAHEAIRPTDFSRDKAASGDHARLYELIWKRALASQMASAKLERTTVDLTDGTGQNVLRVTGQVVLFSGFLTLYEESADDNANDRDGKEGRARLPLLRAGDAPLKKEVRADQHFTQPPPRYSEASLVKKMEDLGIGRPSTYASVIQVLKDRAYVTLERNRFIPSEAGRLLTAFLERFFERYVSYDFTAGLEDSLDEISGGRADWQKVLDAFWHDFKPKTAEVMEQQPSAITAELDKFLEPWLFPDKGDGHDPRECPSCHTGRLALKGGRFGAFIACSNYPECKYTRGFGQGEDGVDDNEPVLLGYMPENSDDDGYMAFSDQGDILPANTASASETGVTDGGIAANAAFSGKGNSASHTDRDDLPFDPDEPASSTGNVASSQSRMTGDETASSGNSRDSSAHGVSTTAGIDAESQAGISNQALAGKNNAGRTAVSDNKGNNSSSTIAAARKGGSTDDNATVSDPDGDIGSGASSSGQDADNRLLSHRNGDIDSRAIPADHKDSSSDQNASHALSPDRNSDDASVSNSDKKIDSKAVSTGHDVGNAITSDNSPSDNVAHLASTPSSATSSVKVALETENNDTAASKADEQAKEEEESRKARAVTRRTGRFGPYIQLGEGKNAKRVSVPRDVNPREVDFSLASRLLALPREIGLHPESGKMIIAGTGRYGPYLNCDGKYARLSSTEELLDIDIDRAVVKLAEAAQNKGRTGATLSREPLKVFGDSPVTEKPVQLMNGRYGPYVTDGETNASLPKDTTPESLTFEEALALLEARAKMPKKKKTKKAAAKKPAAKKTTTKKAAPKKATTKTATPKSATTDNATSEDGDATPAKSPAKKAVAKKTTAKKPASKSATKKAPSSKTTAAKKTSKATPKDEVAE
(566) DNA topoisomerase 1 [Novosphingobium aromaticivorans DSM 12444]
1
MQLVIVESPAKAKTIEKYLGPGYKVLASYGHVRDLPVKDGSVRPDEDFAMDWELYGDKQARVKAISDAAKGADRLILATDPDREGEAISWHVRELLAKRRVLPKEVERVTFNAITKQTVTDAMKKPRALDQDLIDAYLARRALDYLFGFTLSPVLWRKLPGAKSAGRVQSVALRLIVEREREIEAFRAQEYWSVIARLEHAGTEFAARLVKFDGQKLDKLTLGDEGAAMRAKGVVEAATFRVEEVETKPTRRNPYPPFTTSTLQQEAARKLGFSASHTMRVAQTLYEAGAITYMRTDGVQMDPSAISAARKAISDRYDGHYLPEKPRHYETKAKNAQEAHEAIRPTDFSKDRYGSADEARLYDLIYKRAMASQMASANIERTTVTLRDGTGKHELRATGQVVKFPGFLAVYEEGRDQKQDGDEEDGSLLPAMASGDTPAKRGVDATQHFTQPPPRYSEASLVKRLEELGIGRPSTYAATLQVLKDRNYVRTEKNRFFAEESGRLLTAFLERFFPRYVAYEFTAGMEEELDDVSGGRAEWKKVLADFWRDFKPKSDEVMEKKPSEVTAELDEFLSDYLFPPRADGTDPRLCPKCEEGRLSLRGGRYGAFVACSNYPECKYTRKFAQPGGADGDGGEDGALGKDPETGLEVVRKAGRFGPYIQLGDGKEAKRASIPKDIGELDLEWALKLLSLPREVGVHPETGNPITASIGRYGPYLAHDGKYARLKSTAEVFETGMNAAVMLLAAAAAGAGARGSRAAAEPLKVFGAHPTSGGEIKLMAGRYGPYVTDGTTNATLPRDKQPEALTLEEAITLIDERAAKGPAKGKKKAPAKKASAAKKPPAAKKAPAKKAAPKKAAAAE
(1132) DNA topoisomerase III [Azospirillum sp. B510]
3
MATLIITEKSSQAKDLRAALGDRFGRILPAEGHLLRLAEPDEVDPAWKRWSPTLLKPDGLYPTRPDQGGNKAAKLQAITTALRACDEVILATDCDREGQLIGQEILEHVGYRGKVRRALFTAQDPKTLRDAFAALKPNDSMRPLYEAAVARQQADQIYNLSLTRTATKTLLAPGTRGVIGIGRVKTPTLAIVCLRELEIRDFKPEDYFEVVATANVAEGRFLMRHAPAPKDRIKDRATAEAIARAADQHRGPLTVTVEEKRQAPPRLYDLPSLQKTCGQRWGWTADRTLAVAQELYDGDGKKLITYPRAEARYLSENQIGDAPAIVGALTRLRGFAHLGEHMDVRRPVIRKGKSGHFCDKALEGVSHHAVIPNVNVLDDLESRLGRLSDDEKRLFALICRSYLAAVMPDYEYRQTGVTMPVPVPPPEGARTEGAKPVAFRAVGRIPLKLGWKAAFGSAETEDRSGGKPEEEAEQTLPPLRDGEPATLTDPKVEAKRTQAPPRYNEGTLVDAMQNAWRFVEDPALRDRLKEAKGIGTPATRAEVIKGLRKQNLLGADGKWLVPTPAGLHLFETLRAAAPTLVDPGTTALWEMKLDEVVTGRADFRGVIDAIAGEADRLIGALLGQRGTMLDLGQPAAKTRFTRRRTGATRAASAQTGAPAAPKGRRTRKATVVPADGAAMPPKPRRTRKAKEAAVAPPVTGSAVAQPMESQAGPEARRRREPTERMVAFARSLAERKGIALPDPCLRDFERCRSFLDEHAR
(187) DNA topoisomerase 1 [Azospirillum sp. B510]
1
MPGSNVVIVESPAKAKTINKYLGDDYTVIASFGHVRDLPARDGSVRPDEDFAMEWELGDRSKRHIDEIAKAVKSADRIYLATDPDREGEAIAWHLSELLREKHLSDNRDVQRVTFNEITKSAVQTAMANPRAVSQELVDAYLARRALDYLVGFTLSPVLWRKLPGSKSAGRVQSVALRLICERESEIEVFKPQEYWSIAVGFTTPSGSAFTASLTQLDGKRLDKFGLPNREAAEAAVAKILPRSFAVSSVERKQSRRNPSPPFTTSTLQQEASRKLGFGATRTMRTAQKLYEGVDIGGETVGLITYMRTDGVSLSQEAIDGARGLIGSHYGERYVPDQPRVYKTAAKNAQEAHEAIRPTDLHRRPETVAAYLEQDELRLYELIWKRTLASQMESAVLDQVAVDIASPSDNGAKAVVLRATGSIVVFDGFLKVYQEDRDDAAEDEQQERRLPAMDQGDALARGDIAQDQHFTQPPPRYSEASLVKKLEELGIGRPSTYASILQVLQDRNYVRLDKRRFIPEDRGRLVTAFLENFFHRYVEYNFTAELENQLDEISDGKIDWKTVLRDFWTAFDVAVNGTKDLTITQVLTTLDNELGAHFFPAATEGGHDPRVCPVCREGRLGLKLGKMGAFIGCSRYPDCRYTRPLAVANDENGEAQEGPRELGNDPETGLPVTVRRGPFGAYIQLGPAPAAATPPEEPAAEEPAADGKKPKAKKKKKDEAPKPKRVSLPKGMAAADVDLDTALRLLALPRAIGNHPETGEEISAGIGRFGPYLKHGSVYKSLTADDDVLTIGINRAVDLLAGAAKKASAPAKTLGDHPKTGKPITMGSGRFGPYVKHASVYASIPKGTEPDSVTLEQALELIEAKVAKDAAKKGKAPKDAEPAKAEGAEAEKPAKAKVPAKKPAAKKATKAKAAKDAPAETAAPKKKTVKAS
(1111) DNA topoisomerase 1 [Hyphomonas neptunium ATCC 15444]
1
MKLVVVESPAKAKTINKYLGKDYKVLASYGHIRDLPSKNGSVDPENDFEMVWEADSKSAKRISDIANALKDADTLILATDPDREGEAISWHLVEALRKRRALKKDVAIERVVFNAITKSAVTQAMEHPRAIDAELVDAYLARRALDYLVGFNLSPVLWRKLPGSRSAGRVQSVALRIVCDRENEIESFRAQEYWNIVAELRAPDGTAFEARLHSLDGETLKKFTLGNQGDANRALEIVKVGGYSVVSVEAKPVKRNPPPPFITSTLQQEASRKLGFNAKRTMQAAQKLYEEGRITYMRTDGVNMAEEAYVAARTMIQSNYGARYLPENTRRYSSKAKNAQEAHEAIRPTDFNLRPEDYHGDGDLKKLYTLVWRRAVASQMETALFERTTIDLASKDKRAGLRATGQVLVFDGFIKLYTEGHDAGDDDDDAEGRLPKMAEGQHADLLKADANQSFTQPPPRYTEASLVKRLEELGIGRPSTYASTMSTLEDRGYVRIEGKALVPEDKGRLVTAFLENFFSRYVEYDFTAGLEEKLDVISDGKLDWKAFLREFWQQFAADIDGTKDLRVSAVLDALNEALGAYVFPRQDAEGNPIENPRQCPLCKEGELSMKLGKFGAFVGCSRHPECKYTRQFSSEGGDAAINPDGNEIGIHPDTGAMILLKSGRFGPYVEMANGEKPKRASLAKADNAAELTLERAVELLSLPREVGPHPEDGEMILANFGRFGPYVQHGKTYANLKDPRDVFTIGVNHAVSLIEDKKARGSARGGAAALKALGDHPDGGAIEVFEGRYGPYVKWGKVNATLPKEITPDVVTLEQAIELVNAKGGSAKKKAPAKKAAAKKPAAKKAAPKKKAPAKKAEE
(1028) DNA topoisomerase 1 [Hirschia baltica ATCC 49814]
1
MQVVVVESPAKAKTINNYLGKDYIVLASYGHIRDLPSKDGSVDPDADFAMKWEGDSKSNKRIKDIADALKGADGLILATDPDREGEAISWHVLDVLSKKRGLMKDKKIERVVFNAITKKSILEAMQNPRSLDQELVDAYLARRALDYLVGFNLSPVLWRKLPGSRSAGRVQSVALRLICEREVEIEAFKPEEYWTIKGLMDSVSKTEFEARLYELEGKKTQKFSFPNKEAADKALEVVRVGGYTVQSVEAKPVKSNPPPPFTTSTLQQEASRKLGFNASRTMGAAQKLYEAGLITYMRTDGVEMAQEAIHAARDAIKERYGAPYVPSSPRIYTSKAKNAQEAHEAVRPTDFLKHPSEVRLEADLQRLYDLVWKRAVASQMATAQLERTTADLKSKDGQAILRATGQVVKFDGFLTLYQEGKDDANGDEDAKRLPAMSVGDVIDLKKADANQSFTQPPPRFTEASLVKKMEELGIGRPSTYASTLATLRDRDYVEMDKNRFVPADKGRLVTIFLENYFNQYVQYDFTAELEEKLDLVSDGKLEWKVFLAEFWKQFSLKIAEVMELRVTNVLDLLNDVLGPKIFPPKLDEKTGEPTGEDPRLCPLCKEGQLSMKLGRNGAFIGCSNYPECKHTRPFTTDGSDAEDAVSPDGKLLGQDPETGKDISLRTGRFGPYVQLGEGIGKEKPKRGSIPKGWKADELTLAQAIQLINLPREIGPHPEDGEMMYANFGRYGPYVQHQKTYANLPDPMDVFEVGLNRAVALIAEKNAKGGRGGAAKALKELGKHPDTDEPINVFDGRYGPYVKHQKTNATLPKDLTPETITLEKAIELINAKAGASKKKAPAKKKAPAKKTAAKKAPAKKAPASDS
(1756) DNA topoisomerase 1 [Parvularcula bermudensis HTCC2503]
1
MQVVIVESPSKAKTINKYLGSDYKVLASYGHIRDLPSKNGSVDPEADFSMIWESDARSKKHVSDIVDAVKAADGVILATDPDREGEAISWHLLEVLDKKKALKDKSIQRVAFNAITKRAVEEAIANPRTIDQDLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLICERELEIEKFIAEEFWTLEANVSADDSPQFAARLVKLDGTKVEKFTLTTEEDGSRAKKAVEDAQFLIKSVEAKPTRRNPAAPFTTSTLQQEASRKLGFNARRTMQTAQRLYEGITIGGETTGLITYMRTDGIDMAPEAVMAVRDEIKSTFGADYLPSSPRMYKSKQKNAQEAHECIRPTNFARHPDALKQLDQDQYRLYDLIWKRAMACQMETARLEQTTIDIESRDGKTGLRATGSVVVFDGFLKLYAEGRDDTEDEKDRSLPKVSEGSDAQVTDPTPEQHFTQPPPRFTEASLVKRLEELGIGRPSTYASIISTLQDRSYVTMDKNRFIPDDKGRIVTAFLENFFGRYVEYDFTAKLEETLDDISNGEMAWKAFLRRFWDEFHARVEDMSDLRISEVLDALNEALGPHIFPQREDGRPPRECPTCGEGELSLKVGRYGAFIGCSRYPECKHTRPLGQSEQGNAPAEDRQLGVDPDTSQAVWLKSGRFGPYVQLGEPDPDTKEKPKRSSIPKSWDAASLDFDKAMKLLALPRDVGPHPEDGEMIEASLGRYGPYVKHGKLYANLESIDDVFDIGINRAVAVLEDKKANPRGRGRSAAKPQRELGNHPDTDELVAVYDGRYGPYVKHQKTNATIPQGVDPAEITLEQALELISAREAKKPTKKKKTAKKKSAKKPAKKKTTKKAAKKATKKTTNSAGKD
(1811) DNA topoisomerase 1 [Magnetococcus marinus MC-1]
1
MTAVVIVESPAKAKTINKFLGRGYKVVATYGHIRDLPSKNGSVDTEHGFAMKYSVPKDSTKRVDELAKAVKGAEQVLLATDPDREGEAISWHVYEVLNEKKLLENVQVKRVVFHEITKTAIQDAVAHARDVDMDMVNAQQARRALDYLVGFNLSPLLWRKVRRGLSAGRVQSVALRLVCEREAEIQAFEAREYWSITALAAQAAQSAPRPFEARLAVADGEKLSKFSIGDEAYAKRLIKAVEKRPLYVSEIEKKQSKRNPAPPFITSTLQQEASRKLGFSAKKTMTVAQRLYEGMEVPTADGGKETVGLISYMRTDSVNLANEAIESIRKQIEIRYGKEYLPKSPRKYKSSAKNAQEAHEAIRPTDVIRTPEMLREILEKDQFRLYELIWKRTVACQMAQAKIDKVAANLSVDSQDPNAAYRFRATGSSVAFAGFMKVYMEGKDEVSAQDREDDDDDNESILPPLEVGQQLEQKSLDARQHFTEPPPRYTEATLVKVLESYGIGRPSTYAPTMSTLQDRGYVKLDARKFYPEDVGMVVNSYLTKHFSTYVDYNFTANLEDQLDAVSRGEKSWVPLMEDFWQPFIQQITLKDETTSKEEVTTEQIDEPCPKCGAPLSIKLGRFGKFKACTGYPECKHTEPLNKEEEVSRPEPELTDIPCDKCGKPMLIKEGRYGKYYGCSGAPECKNNQPLNKPRDTGVACPSCGQGTFLEKKSRRGKIFYSCSNYPKCKQALWDEPLEIPCPKCQAPFVTKKVTKTRGTEHICVAEGCDYKEVVEAPIKTSKQ
(654) DNA topoisomerase [Magnetococcus marinus MC-1]
4
MILYLCEKPSQGRDIGRVLGATSRHEGYVAGAGVCVTWCIGHLMEMVAPDGYRPEWKSWRLDTLPIIPQQWQLELTARGRKQFKVIQGLLKGVTEVVLATDADREGETIGREVLERCQYRGKISRLWLSALDDASIRKALGNLLPGEQTEPLYQAGLGRSRADWMVGMNLTRAYTLLGRQGGYAGVLSVGRVQTPTLKLVVDRDRLIENFKPVDYFEIFALHRVHSGTFIAKWVPPPKPCDAEGHCLDRTLAETVIHKVQGHSGTITKAETKRVKEPPPLPLELSTLQQEASRRWGMGAKQTLEIAQSLYEKHKAVTYPRTDCRYLPSNQFKEAPAVLQGLTTNDASLTPLVEGADAQLRSKAWNDKKITAHHAIIPTAAKINIDALSREEALLYDLIRRHYLAQFYPPFEYDRTVIDTQVAMETFHATGRVELIPGWKRVLAANQEKKEGDEDEQTLPVVRSGEAATIEGAELKQKQTKPPNRYTEGTLIQAMKSVGKLVEDARLRKILRETSGIGTEATRAAILETLIKRNLLAKQGKKSLVSMPAGRLLVDALPHSVTDPATTAVWEQTLDDIAHGGGSLETFLAKSELWLNKLIHNVHQRQQLGLNPFRGLPPSTSHTDPAQPTPRRQRRSKAEVTPTPNAAPLCPQCGGPMLQRKSPQGAFWSCAEQATCTGTRPGSPLAAHSPLMQPNPERGPLCPKCQQAPLVQRTAYRGKNSGQPFWGCQRYPQCRYTQASQTTES
(121) DNA topoisomerase 1 [Maricaulis maris MCS10]
1
MNVVVVESPAKAKTINKYLGADYTVLASFGHVRDLPAKDGSVKPDEDFEMAWEIDTASAKRVKAIADAVRESDRLILATDPDREGEAISWHLLEALQKRRVLKDVTVQRVAFNAITKPAILEAMAHPRAVDMELVNAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICDRELEIEKFRSEEYWTVDADLTANSDSFRAKLVTLGGKKLQKLSIKDRASANAAVEAVNSANLSITGVEAKPAKRNPPPPFTTSTLQQEAARKLGFSATRTMQTAQKLYEGVTLGGETTGLITYMRTDGVTMVPEAVSQARDVIGKEHGSLYVPSAPRHYASKAKNAQEAHEAIRPTSFSRLPEKLSLDADMARLYQLIWRRAVASQMESARFERTTVDIASPDGQTALRAVGTVQLFDGFLALYQEGRDDEEDEGENRLPKLTQGAAATVAKTHADQHFTQPPPRFTEASLVKRMEELGIGRPSTYASTLQVLRDREYVQMEKNRFHPFDKGRVVIAFLENFFARYVEYDFTASLETQLDKVSAGELDWKQLLRDFWTDFRAAIDEIGELRITNVLDALNEALAPHIFPEKEDGTDPRLCPSCKEGTLSLRLGKFGAFLGCSNHPDCSFTRQMSPPGEDDAQGDRVIVQHPETGKDVELKNGRFGWYLQMQLDGEDKPKRSSIPKGWDAATLTEEQAIKLIDLPRTVGEHPDDGQPITANIGRYGPYVHHDKTYANIPSVEEVFEIGLNRAVSVIADKRANGGRRGATASALKELGEHDGKPVRIMSGRYGPYVKYEKINATLPKDTDPESVTLEQAMEWVEAKAAKGGKKKAPAKKKAPAKKKAPAKKATAKKPAAKKTAAAKDKAE
(700) DNA topoisomerase 1 [Granulibacter bethesdensis CGDNIH1]
1
MPHDVAIIGILMTDVVVVESPAKAKTINKYLGGNYTVLASFGHVRDLPPKDGSVRPDQDFAMDWEADERGRKQVAAIAKALKGAETLYLATDPDREGEAISWHVRAMLEEARALKGVEVRRITFNEITRNAIRHAIEHPRDLDQPLIEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIEVFRPREYWTVETHFFTPAGAPFTARLTHLDGKKLDQFDLNTEALAMRARALVEQGQFHVGMIERKKVKRNPPPPFTTSTLQQESSRKLGFGAQATMRLAQQLYEGVEIGGETVGLITYMRTDGVQMAREAMFSIRDHVKDSYGLDYLPAAPREYSSKAKNAQEAHEAIRPTDVERTPDSVARYLNPEQRRLYELVWKRAVASQMQSAELDQVTVDIFPQTGDAKSVQLRATGSIIAFDGFLKLYREGQDDTEEEEGRMLPPMAERDPLRQDRVDASQHFTQPPPRYSEASLVKRMEELGIGRPSTYASILSVLQDRNYVRLDKRRFHPEDRGRLVTAFLTSFFERYVDTNFTASLETQLDEISDGRADWRQVMQAFWQDFYQAVEQTKDLKISDVIDALDRDLGPHFFPTREDGTDPRICPACGDGRLGLRLGRHGSFIGCSNYPGCSYTRRLGIDGAEGEAETLKEGMRVLGQHPETGEDITVKRGPYGLYVQQGEAEEGSKKKPRRASLPRGVDGETILLDQALGLLSLPRLVGIHPETGEPIEANLGRFGPYVKMGGIYGNLDKDDDVLTVGLNRAVDVLAKKMASIRTLGTHPKDKEPVVVRKGRFGPYVQHGQVVANVPREIEMDDVTLDDALGWLAEKGKPLKAKGGRKVAAKSSGKKAASADGNEAQPLKKATAKKTTRAAGAGKAAAKKSGTRSATAKTAKAER
(1149) DNA topoisomerase 1 [Xanthobacter autotrophicus Py2]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHVRDLPSKDGSVDPDADFRMLWEVDPKAQKRLNEIATAVKGADGLILATDPDREGEAISWHVLEVLKQKKALKDQKVERVVFNAITKQAVLDAMKAPRAIDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIETFVQKEYWSILARLATPRAEEFEARLTGADGKKITRLSVGTAEEAKAFRAALEAADFRVRSVEAKPMRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDVGGETVGLITYMRTDGVDMAPEAVAATRSAIGKQFGPKYLPGVPRKYTTKAKNAQEAHEAIRPTDPSRHPREVARHLDGEQAKLYELIWIRTVASQMESAELERTTADIEAKAGGRTLDLTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSANEKLNRRDILTTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLESFFKRYVEYDFTADLEEKLDEVSAAELDWKEVLRAFWQDFHTAVEATKDLRVSQVLDALDEMLTAHIFPPTQDGSDPRLCPTCGNGRLSLKMGKFGAFIGCSNYPECRHTRPLTGDGAPEGDGKRELGIDPESGEDVTIRAGRFGTYLQLGEGKDGEKPKRSSLPKGLAPADVDLETALKLLALPREVGKHPEDGEPILAGIGRYGPYVQHGRTYANIEDGDDILAIGLNRAVVLIAEKQSKGRGGRGAATPGRTLGDHPTLGGPVTVRPGRFGPYVNHGKVNATLPKSVDPEALTLAEAVTLIDAKAALSPSKAKAPRKAATKAAASGEDAPAKAATKTAAKKPAAKSAAKKTATKQPAAKKTTKTASKGPKAAE
(140) DNA topoisomerase [Methylobacterium sp. 4-46]
3
MFFFEKPSAMRELQRFFRAPTTVCIAAEGHLLAAQEPAEIRPAWKAWRFEDLPIAVDEIPLCCGQSRSGASHAARIAAIRRALDGVERVIIATDPGREGSMIAWEVLEHLGYRGRVDRLRLGALDEVSIRRAFAALGRDPDSGERDYAAYQEALCRRYEDWHLGLNGTRAVSLRLRPAAFREPWRFGGVQTPTLALLADLERRIRDFVPREFFRIALPVATVSGAELTLWHAPKERIFAREEAEAIAAAARGWAGPLAVAERDVRRPPPRLFSKDTLARRCAKSFGFDPQRTASLAQDLYDRGFLSYPRTESEHLPESQSGDAPAVLAALGASLPDLAGLVPAPGAVVLRRGPRGHYVKDPGEHHAIVPLRKVPRPGEVGPEAWRLWELVAKAFLAAHLPDGIDARTTVSAEVATALGPKRFAVTGSVVRAPGWRAVYGAEAEDEEPVPGKAKREDEPSAGRLPPVAPGEAARAGEARVEGAMTEPPRRITRGELPVVMGRLIDQVEDPALKRALENPANPNEPRGLGTAATRDAVLPKLEKSGYVVLGGALPADARAGAGGNAPRRRRDTPGRADRGGGGARGRDPTITVTEAGLAFIDAVRRVFPAYGDPVGRAVFEADLAEIGRAATRAEAVSRAETFRQRTRARLDALIAAVAGLERAAVEGPAAAPAGRPPSDAMVAFATALAARKNLPLPRGVARDAAVCRRFLDAHAEKREPTAPGAPRPPTPAMLRYAESLAREAGLPDLPEEARTEFAACRAFLDAHARPAPAEARERAGPRRPGAGRPRRRPARSPRARTAGTALGEPA
(167) DNA topoisomerase 1 [Methylobacterium sp. 4-46]
1
MKVVVVESPAKAKTINKYLGHDYEVLASFGHVRDLPAKDGSVDPEQDFKMLWELEERGAKRVSEIARAVKGADTLILATDPDREGEAISWHVLEALQAKRVLKDVAVERVTFNAITKDAVQTAMANPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFKPREYWSLVATLATAKGATFEARLVGADGKRIQRLDVGTAEEAEAFRRDLELATFAVASVESKPAKRHPQPPFTTSTLQQEASRKLGLAPAQTMRIAQRLYEGVEIGGETVGLITYMRTDGVDMAPEAIRDARRVIGAEFGDAYLPGAPRSYSVKAKNAQEAHEAVRPTDLGRLPKEVARFLEPEQAKLYELIWIRTIASQMESAELERTVVEIAAQVGPRRLDLRATGQVVRFDGFLTLYQEGKDDEEDEESRRLPPMQAGDPLRRERVAATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQVLRDREYVRLDKKRLVPEDKGRLVTGFLESFFQRYVEYDFTADLEEQLDRISNAEIDWREVLRDFWRDFSAALAGTKELRTAEVLEALNQLLGPHIFPPRADGANPRACPNCAGGTLSLKLGKFGAFVGCSNYPECKYTRQLSAAGLDGDGEGSAGEGGQPGVRVLGEDPATGLPVTLRDGRFGPFVQLGEASAEKGAEKPKRSSLPRGLTPADVTLETALKLLALPREVARHPESGEPILVNLGRFGPYVQHGKTYANLGKDDDLLEIGANRAIDLIVAKEQGGGRPAADPGRVLGNDPEGRAVTVKAGRYGPYVTDGEVNATLPKGADKEALTLEEALRLIVARREAGGGTKKKTSGRARAARKTEAKPAAKAKAEKAAKPAAAGKSASAGKSASAAKSATAPEKAPARKKAAAAE
(1512) DNA topoisomerase 1 [Methylobacterium radiotolerans JCM 2831]
1
MKVVVVESPAKAKTINKYLGRDYEVIASFGHIRDLPPKDGSVDPEQDFRMVWELADRGASRVSEIAKAVKGADKLILATDPDREGEAISWHVLEALTARKALKGIPVERVTFNAITKASVEQAMRKPREIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWTLIATLTTADGATFEARLVGADGKRIQRLDVGTGEEAAAFRRDLELATFQVASVEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQRLYEGVDIGGETVGIITYMRTDGVDMAPEAIQDARRVIGKEFGDRYVPDVPRKYSVKAKNAQEAHEAVRPTDMGRLPKTVARHLEPEQARLYELIWTRTMASQMESAELERTTVDVTAKVGPRTIDLRATGQVVKFDGFLTLYQEGKDDEEDEESRRLPPMKAGDPLTRERISATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVKIEKKRLQPEDKGRLVTGFLESFFRRYVEYDFTAGLEEQLDRVSNAEIDWRAVLRDFWRDFSAAIGETKELRVADVLEALNGLLGPHIFPDKGDGSNPRTCPTCGSGQLSLKLGKFGAFIGCSNYPECKYTRQLSATGIDGDGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFLQLGEASTEKGAEKPKRSSLPKGLSPSDVDLNKALALLALPREVARHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRLAADPGRPLGKDEASGRDLVVKAGKYGPYVTDGEVNATLPKTMSAEALTLDEAIALVNAKRAAGGGKPAKRGAARKSSARAASGDKPAAKKTATKKPAAKKAATKKSSSG
(300) DNA topoisomerase 1 [Rhodospirillum centenum SW]
1
MPGHNVVIVESPAKAKTINKYLGQDFTVLASYGHVRDLPPRDGSVRPDEDFEMDWELGDRSKRHIDEIARAVRGADRVYLATDPDREGEAIAWHMKEVLGERRLLGKVDVKRITFNEITKSAVQTALAQPRDVNRELVDAYLARRALDYLVGFTLSPVLWRKLPGSKSAGRVQSVALRLVCEREAEIEVFRPQEYWTIEADFRTQEGQTFTARLSQLDGKRLEKFTLGTQGDADAAVARIRPMTFRVGRIERKEVRRNPFPPFTTSTLQQEASRKLGFGATKTMRTAQRLYEGVDIGGETVGLITYMRTDGVALSQEAIDAARRLIDESWGRSYVPEKPRIYKAAAKNAQEAHEAIRPTDLFRRPEHVARYLEKDELALYELIWKRTLASQMASAVLDQVTVDIISKGAEAVFRATGSVIRFDGFLKVYQEDKDDADEDEDHRRLPPMRDGDDLARGEIRPNQHFTQPPPRYSEASLVKKLEELGIGRPSTYASILQVLQDREYVRLEKRRFIPEDRGRLVTAFLESFFPRYVEYTFTADLEGKLDDISGGRIDWKQVLREFWRQFSAAVEDTRDLTITQVLTALDELLGPHFFPRRLGPDGQEVDARVCPTCGTGRLSLKLGKSGGFIGCSNYPECRYTRPLSVAGEGGEAESGDRMLGNDPETSLPVWVKTGRFGAYVQLGNGDGKEEKPKRASLPRGMLPATMDLDTALRLLALPRSLGTHPESGLEIVAGIGRYGPYLKHGASYKNLTAEDDVLTIGLNRAVVVLGDAPAKKAVAGRELGAHPKDGKPVKVGSGRFGPYVQHNKLFASIPKSMSADTVTLAEALELLAAKAAKDGAKKGPAKAEGGEEAAATPAKKTTAKKAPAKKAPAKKTGAAKAESAGTDAEAETAEKPARRTAAKTTKAPAKASAAKASGTKAATRKAAAGD
(1832) DNA topoisomerase 1 [Gluconobacter oxydans 621H]
1
MTDVVVVESPAKAKTINKYLGSGYTVLASFGHVRDLPPKDGSVRPDENFAMSWQTDERGAKQISAITKALKGAKNLYLATDPDREGEAISWHVRSVLEEKKLLKNVDVHRVTFNEITKSAVTAAMAAPRELDRPLIDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIEVFRPKEYWTVTGGFTTPGKAAFQARLTHLKSEKLDQFDLNNEQLAFGARDTVLGGQFTVRSVERKRTKRNPPPPFTTSTLQQEASRKLGMSAQTTMRTAQQLYEGVDLRGETTGLITYMRTDGVTMAKEAIGSIRGHIGKAFGDEYVPDYPRSYSTKAKNAQEAHEAIRPTDVFLTPQQVAHALTPEQKKLYELIWKRSVASQMQSAELDQVAVTLADASGQTLLRATGSTIAFDGFLKLYIEGRDDTKAEDEDGKLLPPMKEGDRLTTGAVEAEQHFTQPPPRYSEASLVKKMEEIGIGRPSTYASILGVLRDRNYVRLDARRFVPEDRGRLVTAFLTSFFERYVDTGFTASLEEQLDDISGGRADWHDVMAAFWHDFSAAVAQTKDLKISDVIDALDEDLGPHFFPPRPDGADPRVCTSCGTGRLGLRLGKFGAFIGCSNYPTCQFTRRLVAEEGDTEGLNDGPKVLGQDPETGEDVTIRRGPYGLYIQRGEPNPEDKKAKPKRTTIPKGLDGNTMTLEQALGLLSLPRLVGLHPETGEKIEAGLGRFGPYVKMGAIYGTLDKDDDVLTVGLNRAVDALAKKLASIRNLGPHPKDGEPVMIRKGRFGPYAQHGQLIANLPKGQDMDEVTLDEAVALLAEKGKPLKGGAKKTSAKKAAPKAAKAKKNVAAAEGDETAPKKVTKRSPAKSATKTKTTTPRKRKTVSDTSSEG
(498) DNA topoisomerase 1 [Acidiphilium multivorum AIU301]
1
MNAIVVVESPAKAKTINKYLGDGFTVLASFGHVRDLPPKDGSVRPDEDFAMSWEEDARGDRQVAAIAKALKGADTLYLATDPDREGEAISWHVRAMLEARNVLKGKQVRRITFNEVTKSAVQAALRAPRDLDTPLIEAYLARRALDYLVGFTLSPVLWRKLPGSKSAGRVQSVALRLICEREAEIELFRPREYWTIEAEFRTPAGAPFRARLTHLDGRKLDQFDLADKAAADAAKAAVERGAFSVVSIEKKRVRRNPPPPFTTSTLQQDASRKLHMTAQAIMRTAQQLYEGVEIGGETVGLITYMRTDGVQMAREAITAARQQVKDAFGANYLPAAPREYQSKAKNAQEAHEAIRPTDFTLTPERAARHLSPEQARLYELIYKRALASQMQSAELDQTTVELADAAGTTLRATGSILAFDGFLKLYREGMDEDPEDETARLLPPMAKSDPLASGPVTAEQHFTQPPPRYSEATLVKRMEELGIGRPSTYASILTVLRERNYVRMENRRFIPEDRGRLVTAFLVSFFGRYVETGFTADLEEKLDEVSDGRLDWRSVMRDFWADFSGAVEQIKDLKISDVIDALDEELGPHFFPAREDGSDPRVCQACGTGRLGLRLGRFGAFIGCSNYPECQYTRRLAVEGGEDEGDQLRDGMKLLGENAEGIPVTLRRGPYGLYVQLGEPDPEDKKAKPRRAALPRGMSGETITLEQAIGLLSLPRVIGVHPETKQEIQAGIGRFGPYVKMGPIFASLDKDDDVLAVGLNRAVMVLAKKQEGIRDLGPHPKDGESVTARKGRFGPYVQHGKTVATLPRGSELGAVTLDEAVALLAEKGKTLAPRGRKGAKPAAKPKDAAAPKAARPAKAKAAAKPKAAAAKPKAAAAKAKPAARKTARSGG
(70) DNA topoisomerase 1 [Methylobacterium nodulans ORS 2060]
1
MKVVVVESPAKAKTINKYLGHGYEVLASFGHVRDLPAKDGSVDPEQDFKMLWELEDRGAKRVSEIARAVKGADKLILATDPDREGEAISWHVLEALQAKRVLKDVSVERVTFNAITKDAVQTAMAQPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFRPREFWSLVATLATARGAVFDARLVGADGKRIQRLDIGTAEEAEAFRRDLELATFTVGNVEAKPARRHPQPPFTTSTLQQEASRKLGLAPAQTMRIAQRLYEGVEIGGETVGLITYMRTDGVDMAPEAIQDARRVIGAEFGDAYVPAAPRSYSVKAKNAQEAHEAVRPTDLGRLPKEVARFLEPEQARLYELIWIRTVASQMESAELERTTVDIAAQVGPRRLDLRATGQVVKFDGFLTLYQEGKDDEEDEESRRLPSMAAGEALRRERIAATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQVLRDREYVRLDKKRLVPEDKGRLVTGFLESFFRRYVEYDFTADLEEQLDRISNAEIDWRAVLRDFWRDFSAAIAGTKELRTAEVLEALNQLLGPHIFPPRADGANPRACPNCASGTLSLKLGKFGAFVGCSNYPECKYTRQLSAAGVEGEGDGSSGEGGQPGQRVLGEDPATGLPVTLREGRFGPFVQLGEASAEKGAEKPKRSSLPRGLSPAEVSLETALKLLALPREVARHPETGEPILVNLGRFGPYVQHGKTYANLGKGDDLLEIGANRAIDLIVAKEQGGGRPAADPGRVLGNDPESGRAVTVKAGRYGPYVTDGEVNATLPKGADRDAITLDEALRLIAARREAGGGTKKKATTRTRKSETAAKPAGKATKKAPTKASAAKKKAAAE
(1787) DNA topoisomerase [Methylobacterium nodulans ORS 2060]
3
MARASADRTLFFFEKPSAMRQLQRFFKAPTTICVSAEGHLLAAQEPAAIRPAWKAWRFDDLPIALDEIPVAYARNRSGASHAGRIEAIRGALQGVDRVIIATDPGREGSMIAWEVLEHLGYRGRVERLRLGALDEVSIRRAFAALAREPDSGERDYAAYLEALCRRYEDWHLGLNGTRAVSLRLRPPAFREPWRFGGVQTPTLAILADLERRIRDFVPRDFFKVAMPVETETGAALTLWHAPKERIFDRAEADAIREAAAGWSGPLSVVQKDVRRPPPRLFSKDTLARRCAKRFGWDPQRTAATAQDLYDSGFLSYPRTESEHLPESQSGDAAAILAAIAGCLDDVAELVPAGEAIVVRRGPRGHYVKDPGEHHAIVPLRKVPRRGELGPEAWRLWELVAKSYLAAHLPDGIDARTTVAAEVATPPGPKRFAVTGSVVRAPGWRAVYGSEAEDEDPVPGKARRDDEPTTGRLPPLRDGAAARATDATVETAVTEPPRRITRGELPVVMGRLIDQVEDPVLRRALENPANPNEPRGLGTAATRDAVLPKLEKSHYVVLAKGKDPAITVTEAGLAFIDAVRRVFPAYGDPVGRAVFEADLAEIGRAPSRAEAVRRAEEFRQRTRARLDALIAAVAGSERLAVAAPSPDGAGRPPTPAMVAFATALAARKGLRLPRGLKQDAAICRRFLDAHAEQREAAAPGAPRPPTPAMRRYAEALARENGLDKLPDDAATDFSACRRFLDAHAAPRPDAPAKPSPRKPAPRRRTRPPAGADRHADTSN
(798) DNA topoisomerase 1 [Methylobacterium populi BJ001]
1
MKVVVVESPAKAKTINKYLGRDYEVLASFGHIRDLPAKDGSVDPEADFAMVWELEDRGSKRVSEIARAIKGAEKLILATDPDREGEAISWHVIEALSARKALKGIPVERVTFNAITKASVDAAMRKPREIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWSIVATLATEAGGVFEARLVGADGKRIQRLDVGNAEEAAAFKRDLELATFQVASVEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQKLYEGVDVGGETVGIITYMRTDGVDMAPEAISDARRVIGREFGDDYVPGAPRKYSVKAKNAQEAHEAVRPTDMGRLPKQVARYLEPEQAKLYELIWTRTIASQMESAELERTTVEVTASVGPRRIDLRATGQVVKFDGFLALYQEGKDDEEDEDSKRLPAMAAGDPLKRERIASTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVKIEKKRLQPEDKGRLVTGFLESFFKRYVEYDFTASLEEQLDRVSNAEIDWRSVLRDFWRDFSAAIGGTKELRVAEVLEALNGLLGPHIFPEKADGGDPRACPTCGSGQLSLKLGKFGAFIGCSNYPECKYTRQLSASGVEGEGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFVQLGEASSEKGAEKPKRSSLPKGTSPGSVTLEIALRLLSLPREVAKHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRPSSDPGRALGPHPDGAALVVKAGKYGPYVSDGSVNATLPKTMAAESLTLEQAIELINAKRASGGGKKPVRKTATRARTATKAADGAEAKKPAVRKTASKTASKSTTKAAAKPAAAKKAAAKTKAS
(1752) DNA topoisomerase 1 [Ketogulonicigenium vulgare WSH-001]
1
MPVVVVESPAKAKTINKYLGSDYQVLASYGHVRDLPPKDGSVDTDEDFAMTWEVDANSKKHIKAIADALKADPNLILATDPDREGEAISWHLVEALTDRKAIKKDTPVSRVVFNAITKSAVTEAMQNPRQVDAPLVEAYLARRALDYLVGFKLSPVLWRKLPGAKSAGRVQSVCLRVIVDREVEIEAFRAQEYWTVAAEIETPRGQIFTARLVTLGGKKLDKFDLGNQVAAEMAVQAVTSRALSVQGVEAKPAQRHPSAPFMTSTLQQEASRKFGMGAKATMSAAQRLYEAGLITYMRTDGIDMAPEAVMAARDAIRDKFGADYLPASPRMYKNKAKNAQEAHECIRPTDMTRGVEQQKIVDADQRKLYDLIYKRTIASQMAAARLERTTVDIGAADGQVGLRATGQVVLFDGFLAIYEEGRDDSTDEDEGRLPQMMQGEALKKLAVTPDQHFTQPPPRYTEATLVKRMEELGIGRPSTYASIVTTIQDRGYVQKDKNRLIPQDKGRLVTAFLENYFPRYVEYDFTAGLEDQLDKVSAGDADYKDVLRQFWRDFSAALNETSELRITDVLEKLNEVLSPIMFPPKPDGSDPRACPNCGNGHLSMRTARSGGAFIGCSNYPECRFTRPFGPPELAEGAIGPDGRLLGHDEGDPITLRDGRFGPYVQRGEATEEVPKPPRASLPKTWSPDEVTLERAVSLLNLPRPVGPHPEDGVLIEAGLGRFGPFIKHGSTYANLKSIDEVFEIGMNHAVELLAQKLAGGRGRTAVAKPLKELGDHPDGGAITVMPGRYGPYVKWEKVNATIPKDIEPEALTIEQALELITAKAGKKPAKKPAKKAATAKAATTKAKAAPKAKTTKAKAASADPAKPKRKTAKAAPDVVEDEA
(36) DNA topoisomerase 1 [Ruegeria sp. TM1040]
1
MPVVVVESPAKAKTINKYLGSDYTVLASYGHVRDLPAKNGSVDPEDDFAMTWEVGNDSKKHVRAIAEALKDDNALILATDPDREGEAISWHLQEALTKRRSIKKDTDVKRVTFNAITKDAVAEAMKNPRDVDMPLVEAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVCLRLIVEREMEIEAFNPQEYWSVRANLATPRGQSFEARLTVLGGEKLDKFSLANSTAAELAVQAVSSRKMSVLSVEAKPAARNPSAPFMTSTLQQEASRKFGMGAKQCMNAAQRLYEAGLITYMRTDGIDMAPEAVSAARDEIAKRYGQEYVPGEPRIYKNKAKNAQEAHECIRPTDMSRDAASLKVSEDDQRKLYDLIWKRTLACQMAGARLERTTVDIGSDDKQVVLRATGQVVMFDGFMRVYEEGRDDVVDEDDKRLPQIMQGEALKFAGSLAAQAEKAGKDGSVLSQDGATLALQHHTQPPPRYTEATLVKRMEELGIGRPSTYASVITTIQDREYVRKDKNRLFPEDKGRIVTIFLLNFFKRYVEYDFTAALENQLDDVSAGGKDYKELLDSFWRDFSAAISETSDLRISEVLDVLDEALAPQLYPPREDGGDPRICPKCGAGQLHLKTSRTGGFVGCGNYPECNYTRPISGEGAEGYERVLGEDDGDEIHLKSGRFGPYVQRGEATPENKKPPRSSLPKQGKDYLPGWGPNEITLEQAVTLLTLPREIGAHPEGGVVSSNLGRFGPYIMHQRPDEEKPVYVNLKETLDVFEIGMNRAVEMLAEKRANPGRGRSAAAKPLRELGEHPDDKAPVNIMDGRYGPYVKWGKVNATLPKDTEAKDVTMEMAVELLNEKAAKSGKKKAPAKKAAAKKTTAKKTTAKKAPAKKKEAKASGD
(619) DNA topoisomerase 1 [Sphingobium chlorophenolicum L-1]
1
MQLVIVESPAKAKTIEKYLGGDFHVLASYGHIRDLPAKDGSVDPDAGFAMQWENYGDKGKQLKAIADEAKKATRLILATDPDREGEAISWHVQEVLRAKKALPQKVDRVTFNAITKQAVTEAMAQPRALDEDLIDAYRARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLVVEREREIESFVPQEYWSVAAEMEQGGQGFTARLVRWRGEKIERLTIGREGDAMAAKADVEAGRFTVEKVETKPVSRNPPPPFTTSTLQQEAARKLGFSASHTMRIAQQLYEDGAITYMRTDGVQMDGSAISAARKAIAERYDGGYLPEKPRQYQTKAKNAQEAHEAIRPTEFYRDKVGSGDHARLYDLIFKRALASQMASARLERTTIDLVDGTGQHGLRATGQVVIFPGFLALYEEGRDDTEDDDSKLLPRMAEGDAPAKKKVTAEQHFTQPPPRYSEASLVKKLEELGIGRPSTYASTLQVLKDRDYVRIEKNRFFAEESGRLVTAFLERFFERYVSYDFTAGLEEELDDISGGRAQWQAVLEAFWRDFKPKTTEVMEQKPSDITAELDKFLEPMLFPPKADGSNPRACPMCGDGQLSLRGGRFGAFIACSNYPECKYTRKFGQPGGKDGAEDSGPEVLGKHPETGQDIVRKSGRFGPYIEMGEGKEAKRGSIPKDLPDGEMTLDWAVKLLSLPREIGLHPETGKPIVANIGRFGPYLLHDGKYGRLSSTAEIFEVGMNSAVAKLADAANRGGRGASSREPLKVLGKHPRTEAEIKLMAGRYGPYVTDGTTNATLPKTIEQDALTLEEAAQLIDARAAAAPAKKGKKAPAKKAAAKKPAAKKAPAKKKVAAE
(680) DNA topoisomerase 1 [Phenylobacterium zucineum HLK1]
1
MNVVIVESPAKAKTINKYLGSDYKVLASYGHVRDLPAKDGSVRPDEDFAMSWDVDAKAAKRLSEIAEAAKGADRVILATDPDREGEAISWHVLEVLQKKRALKDAKVQRVVFNAITKSAVTEAMANPRELDMELVEAYLARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLIVDRELEIERFRTQEYWTVEAEVAAGGDPFTARLVKHEGKRLSKFDLGNEASAFAARDAVKAATFKVAAVERKPGRRSPPPPFTTSTLQQEAARKLGFSAQRTMQAAQKLYEGVDIGGETVGLITYMRTDGVQTAPEALDEARAVIGGLYGKDYVPEKPRFYSTKAKNAQEAHEAIRPTSLGRNPGKLRLEGDLGRLYELIWKRMIASQMESARIERTTIDLESADGRTGLRATGQVVTFPGYLAVYEEGRDDPEDEEGGRLPQVAEGAQATVRQAKADQHFTEPPPRYSEASLVKKMEELGIGRPSTYASILERLRDRSYVRMEKQRFVPEDQGRIVTIFLEEFFGKYVEYDFTADLEDQLDQVSAGDLDWKVLLKNFWADFNAKVGELGQIGTREVIDALDESLASTLFPPMADGSDPRVCPRCGSGRLSLKPSRTGAFIGCSNYPECRFTRPFGPPDAEGAEASGDRDLGTDPQTGETVWLKAGRFGPYVQLGEGEKPKRSSLPKGWSVADMDLEKALRLLRLPREIGPHPEDGKPILAGIGRYGPFVQHNGTYANLPSVDEVFEVGLNRAVDLIATKRAGGKRGGEAEALKDLGAHPADGQPVRVLAGRYGPYVKHGSTNATIPKGADPKALTLDEAVKLLAEREAKGGGKKKPARKAKAEPKAKKAPAKKAPAKKAAAKTPAKATPAGDIDDDESPF
(1109) DNA topoisomerase III [Azospirillum lipoferum 4B]
3
MATLIITEKSSQAKDLRAALGDRYGRILPAEGHLLRLAEPDEVDPAWKRWSPTLLKPDGLYPTRPDQGGNKAAKLQAITAALRACDEVILATDCDREGQLIGQEILEHVGYRGKVRRALFTAQDPKTLRDAFSALKPNDSMRPLYEAAVARQQADQIYNLSLTRTATKTLLAPGTRGVIGIGRVKTPTLAIVCLRELEIRNFKPEDYFEVVATASVAEGSFQMRHAPAPKDRIKDRATAEAIARAADNHRGPLTVTVEEKRQVPPKLYDLPALQKTCGQRWGWTADRTLAVAQELYDGDGKKLITYPRAEARYLSENQIADVPAIVGALTRLRGFAHLDIARPVIRKGKSGHFCDKALEGVSHHAVIPNVNVLDDLESRLVRLTDDEKRLYALICRSYLAAVMPDYEYRQTSVTMPVPMPTPGGTKPVAFRAVGRIPLKLGWKAAFGSAESDDRSGGKPEEEAEQTLPPLTDGEPATLSDPKLEAKRTQAPPRYNEGTLVDAMQNAWRFVEEPSLRDRLKEAKGIGTPATRAEVIKGLRKQNLLGADGKWLVPTPAGLHLFETLRAAAPTLVDPGTTALWEMKLDDVVTGRADFRRVIDAIATEAERLIGALVGQRGTLLDLGMPAPKARFARRGTGGRTTGAAAGAAKPVRRRTRKAEAPVEGGAAAPKPRRVRKAKAPASAPPTSAQADNGRPAAPATAPAPPNGLRRREPTERMVAFARSLAERKGIDLPDPCLRDFDQCRSFLDQHAR
(744) DNA topoisomerase 1 [Azospirillum lipoferum 4B]
1
MPGSNVVIVESPAKAKTINKYLGDDYTVIASFGHVRDLPARDGSVRPDEDFAMEWELGDRSKRHIDEIAKAVKSADRVYLATDPDREGEAIAWHLSELLREKHLTDNRDVQRITFNEITKSAVQAAIANPRDVSRELVDAYLARRALDYLVGFTLSPVLWRKLPGSKSAGRVQSVALRLICERESEIEVFKPQEYWSIAVGFTTPAGAGFTASLTQLDGKRLDKFGLPNREAAEAAVAKILPQSFAVSSVERKQSRRNPSPPFTTSTLQQEASRKLGFGATRTMRTAQKLYEGVDIGGETVGLITYMRTDGVSLSQEAIDGARSLIGSQYGERYVPAQPRVYKTAAKNAQEAHEAIRPTDLQRRPDSVAGYLESDELRLYELIWKRTLASQMESAVLDQVAVDIANPSKDVVLRATGSIVVFDGFLKVYQEDRDDAAEDDQQERRLPAMDQGDALARGDIAQDQHFTQPPPRYSEASLVKKLEELGIGRPSTYASILQVLQDRNYVRLDKRRFIPEDRGRLVTAFLENFFHRYVEYNFTAELENQLDEISDGKIDWKTVLRDFWTAFDVAVNGTKDLTITQVLTTLDNELGAHFFPAATADGHDPRVCPVCREGRLGLKLGKMGAFIGCSRYPECRYTRPLAVANDENGEAQEGPRELGNDPETGLPVTVRRGPYGAYIQLGPAPTVAAPPEEPAVEEPAADGKKPKAKKKKKDEAPKPKRVSLPKGMAAADVDLDTALKLLALPRTIGNHPETGEEISAGIGRFGPYLKHGSVYKSLTPDDDVLTIGINRAVDLLAGAAKKASAPAKTLGDHPKTGKPITMGSGRFGPYVKHASVYASIPKGTEPDSVTLEQALELIDAKVAKDAAKKGKAPKDAEPAKAEGAEAEKPAKAKAAAKKPAAKKATKAKAAKDAPAEAAAPKKKTAKAS
(68) DNA topoisomerase 1 [Rhodospirillum rubrum F11]
1
MHVVVVESPAKAKTINKYLGKDYVVLASYGHIRDLPPKDGSVRPDEGFAMDWEIDAKSEKHVKDITQALKSADGLLLATDPDREGEAISWHVRDVLEKRKALVGKQVQRITFNAITRSAVEEALRNPRDLDTPLVEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREQEVERFVSREYWTVDAILASPQGQIFRARLSQLDGQKLDKFGLPDETTALAALERIKAATLRVESVERKQARRNPAAPFTTSTIQQEASRKLYFSARQTMQVAQKLYEGVDLGGETVGLITYMRTDGVSIAPEAVFATRDLIGAEFGAAYLPEQPRVYKTKAKNAQEAHEAIRPTDVARTPQSVAPYLTAEQRKLYELVWKRTVASQMASAILDQVAVDIADPEAKVVLHATGSVIQFDGFLKVYREDFDDRPESSPDGAGEDENRLLPPLREGDGVKREDVKADQHFTQPPPRYTEASLVKRMEELGIGRPSTYASILSVLQDREYVRLDARRFIPEDRGRLVTAFLENFFSRYVQYSFTADLENQLDEISDGKLGWKTVLERFWMDFKAAIEGTATLRVSEVLDALDKELGPHLFPQAEDGHDPRVCPVCSAGRLGLRIGKFGAFVGCSNYPDCKFTRPLVTKEGEGGDGAALAEDGTKPLGKDPVSGEDVTLRKGPYGLYVQKGEAAPVEKGKKAVKPPRVSIPKDMDAATIDLDIALKLLSLPRPVGDHPETGTMISAGIGRFGPYIKHGDIYKSLPKDDDVLTIGLNRAVSLLAEAGKGGRARQPARSLGDHPADTKPVTIHDGRFGPYVQHGGVRATIPRTADPATYTLAEAVELIAAKAAKDGDGKKAPAKKAATKAPVKKAAAEKKAPAKTATKKAAPKKAADSAEDAPAKAPRKSKAKPASADPD
(1771) DNA topoisomerase 1 [Micavibrio aeruginosavorus ARL-13]
1
MSASNLVIVESPSKAKTINKYLGPDYEVLASYGHVRDLPPKDGSVDPENGFAMLWELGDRAAKPVNDIRRAVKKAKALYLATDPDREGEAISWHVQELLKDEKLLEGKQVFRVTFNEITKKAVQEAFKNARDLDAPLVEAYLARRALDYLVGFNLSPVLWRKLPGSRSAGRVQSVALRLICERESEIEKFRADEYWTIEARLHNRDGAPFTARLTHLSGNKLDKLDIGSEAQATAAANRIRGKNLVVQNVEKKQVRRFPPAPFITSTLQQEASRKLGFGASQTMRLAQRLYEGTEINGDTVGLITYMRTDGTTLSEDAVTQCRDVIKSNYGPKYLPDAPRLYKSKAKNAQEAHEAIRPTDLSRTPDEVRMYVDDQMARLYELIWKRTMASQMENAVMDQVGADISDGTTDVVLRATGSTVAFDGFLTLYQEGQDDDETDEENRRLPVLDKGDATKLIDVAQDQHFTQPPPRYSEASLVKKMEELGIGRPSTYASILQVLQDRDYVRLDKKRFIPEDRGRLVTTFLSKFFTRYVDYDFTATLEEELDAIAAGQAHWKDALAQFWKDFSKAVGDTKNLTITEVIDNLDAELGPHFFPVVEHGKDPRICPACNEGRLSLKLGKFGAFIGCANYPDCRYTRPLVVPSADENAEGGEAGGESGLAAQLANAPKILGHDPVTGRAVSLRRGPYGPYVQIDPPEAPPAPAVEEKAPEVEDGTAKKGKGKAKKKKETAEKPKRQGVPKGLKLEDIDLAAALKLLELPREVGLHPETKEMIKAGIGRFGPFLVHQGSYTSIPKGDDVLTIGINRAVDLIAAKAERAANGGGRRGGWGKKKAKADGDDAAPKKTAAKKKAPDKKAAAKKPAAKKTAAKKPAAKKTATKKPAAKE
(1672) DNA topoisomerase 1 [Caulobacter sp. K31]
1
MIVVVVESPAKAKTINKYLGSGYTVLASYGHIRDLPSKDGSVEPDNDFAMHWEADAKGAKRIGDIVDAMKGADGVILATDPDREGEAISWHVLEVLQKKKAIKDKSVQRVTFNAITKTSVLEAMAHPRDIDMELVEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVCLRLIVDRELEIERFKTQEYWSVEADVTAGAEPFVARLVKHENKKLTKFDLNNESSALAAKAAVEKAVFKVAAVEKKPGKRSPAPPFTTSTLQQEASRKLGFSAQRTMQAAQKLYEGIDIGGETVGLITYMRTDGVSVEPEGIAEARSVIGSVYGETYVPETPRYYKAKAKNAQEAHEAIRPTSLKRNPGSLRLESDLGRLYELIWKRMIASQMESARIERTTVDLESADGQTGMRATGQVVLFPGYLAVYEEGRDDEGDEDSARLPMIEEGAAAKVLDARADQHFTEPPPRYSEASLVKKMEELGIGRPSTYASVLTVLRDREYVRMDKQRFIPEDKGRLVTAFLEQFFRRYVEYDFTAALEEQLDLVSDGKLDWKQFLRDFWKDFHAAVGEIAELRTTNVLDALNESLGPHIFPDKGDGSDPRLCPTCGTGQLSLKVGKFGAFIGCSNYPECRFTRQLATAEGEGEAEAADKELGINPATGRAVWLKNGRFGPYVEEPAAEGSGDKPKRSSLPKGWTPAGLDLEKALRLLALPREVGMHPDDGKKITAGLGRFGPFVLHEGTYANLENPEEVFDIGLNRAVALLADKRAGGGRPQRGQAAALADLGVHPEDGKPVKVLSGRFGPYIKHGDTNANVPKGADPAALTLAEAVVLLADRVAKGGGKKPAKKAAAKKAPAKAKAAAATDGGAPAKKAPAKKAPAKATGAKKTAAKKPAAKKAKAEA
(741) DNA topoisomerase 1 [Candidatus Pelagibacter sp. IMCC9063]
1
MNLVIVESPAKAKTINKYLGSNYIVLASFGHVRDLPSKNGSVDTENNFNMVWEIDTASKKHIKEIADAAEDCEKIILATDPDREGEAIAWHVRHILEDKNLLKGKKVERVVFNEITKKAVVYGVENPRDLNIELVNAYLARRALDYLVGFNISPILWTKLPGSKSAGRVQSVALKIIVEREYEIELFKPEEFWTLNAVFKNSQNKEINSKLNIYDSKKVEKFSFKNKKAAENAVAEINKNEFKVKSIESKPFKRNPYAPFRTSTMQQDASRKLGFGASRTMQVAQRLYQGIDIEGETVGLITYMRTDGTDISLDAVADCRTFIKNEIGEKYLPSEARNYSGKKAKNAQEAHEAIRPTDITRTPNSLKSKLDKDQMRLYELIWNRTVSSQMESAEFERTAIDFTNQSSSMIFRANGSIQKFDGFLKLYQEVKDEDDKEKEDSDEDNILPEVVKDEILKIDKVLNEQHFTQPPPRYSEASLVKKLEELGIGRPSTYASIISVLSTRNYVEVLNKKFTPTDRGKLITSFLNQLFTRYVDYNFTAGLEESLDDITTGKADWIEVLAKFWKEFNQNVLEVKELRTRAILDMMNESLGEIIFDKDNEGKIKRSCECGGELSLKTGRFGAFIGCSKYPDCKFTRPMSRIKAAEQDYLAEPKEIGKTEDDKNIVLKKGRFGPYLQVGNDEKEMKNVSIPKGISLDDIDLDKARFLASLPKVLGQYPENSMDITLNNGRYGPYVKCDKKSATLEAPEDIFSIGLNKAITMIADAKPGRRSSNEIKLIGEHPEDKKPVKVMKGSYGPYIKYKTINATIPDDKDPESVTMEEALDLIEKRLEYDSTKKGKKIKKKTAKKRKPKKKADKNKDEEK
(313) DNA topoisomerase 1 [Rickettsia akari str. Hartford]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKASKYVDAIVKDAKKADSVYLATDPDREGESISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDKIERFKSEEYWDISIKIQSSNNELFTAQLTHVNDQKLEKFSIINAKDAKDLTEKLKSQKFHVDKIEKKQQKRAPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDTSYGNKYLPSSPRIYKSKVKNAQEAHEAIRPTNITYTPDNLKELLEKDYYKLYELIWKRTVACQMENVIMDLVVASLASENKEYLAKATGSTITFDGFYKIYRESVDDEDEEENKMLPPLKEQESLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVTLEKKRFIPEELGRLVTVFLVGFFRKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNNNIKSVNEQKITEIISYVQKALDYHLFGENKESKVCPSCKTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEAELSAIPNGNKILGTDKDGIEIYLKKGPYGPYIQHGEQEGKVKPKRSPIPAILNQNDITLEIALKLLSLPLKIGIHKDSGEEIMIGYGKFGPYIKYMSKFISIPKKYDFLNLSLDDAMKLIEDNNAKLETTQG
(699) DNA topoisomerase 1 [Rickettsia slovaca 13-B]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTKKLKSQKFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKIKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDEAEEENKMLPPLKEQEPLKTKEVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKICPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPSENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGQFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
(83) DNA topoisomerase 1 [Rickettsia africae ESF-5]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRIAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTKKLKSQKFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESIDDEAEEENKMLPPLKEQEPLKTKEVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKICPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPATMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMDQFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
(1643) DNA topoisomerase 1 [Rickettsia rickettsii str. 'Sheila Smith']
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDATKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTQVNDQKLEKFSIINEKNAKDLTKKLKSQKFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDEAEEENKMLPPLKEQEPLKTKAVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKICPSCHTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIIIGYGKFGPYIKYMGKFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
(1876) DNA topoisomerase 1 [Rickettsia conorii str. Malish 7]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTKKLKSHKFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDEAEEENKMLPPLKEQEPLKTKAVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKICPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGQFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
(900) DNA topoisomerase 1 [Sphingobium sp. SYK-6]
1
MKLVIVESPAKAKTIEKYLGGDYRVLASYGHVRDLPPKDGSVDPEHGFAMAWENYGDKARQLKAITDEAKKADELILATDPDREGEAISWHVQEVLRAKKALPERVERVTFNAITKATITEAMKHPRALDDDLIDAYRARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLIVEREREIEAFVSQEYWSVTALLEQGGQRFDARLVRWRGEKLDRLSIGKEGDALAAKADVEAGRFTVSSVETKPATRNPPPPFTTSTLQQEAARKLGLSASETMRVAQQLYEDGAITYMRTDGVQMDESAISAARNAIAKRYDGGYLPDKPRHYQTKAKNAQEAHEAIRPTDFSRESAGSGVHAKLYDLIFKRALASQMASARLERTAVELTDGTGQHVLRATGQVVLFPGFLALYEEGRDDPVGRQGAGDGEDEESRLLPALKAGDQPAKKDVRADQHFTQPPPRYSEASLVKRLEELGIGRPSTYASTIQTLKDRDYVRIEKNRFFAEESGRLVTAFLERFFERYVSYDFTAGLEEELDEISGGRAQWQQVLEAFWRDFKPKTAEIMEQKPSEITAALDEYLAPMLFPDKGDGSDPRLCPLCHDGRLSLRGGRYGAFIACSNYPECRYTRKFGQPGGADGDAAGGNEELGTHPETGEPILRKSGRFGPYVEMGSGKEAKRASIPKDLPNGELTLDWATRLLSLPRTIGDHPETGKPITASLGRYGPYLAHDGKYARLASTAEIFETGMNAAVAKLADAANRGGARKAAEPLKILGAHPRTEAEIRLMEGRYGPYVTDGTTNATLPKTVAPDALTLEEAAQLIDERAAKAPAGKRKGKAKSSAGKSGAAKKTTVKGKAPSKAKSKAPAAAE
(138) DNA topoisomerase 1 [Sphingobium japonicum UT26S]
1
MQLVIVESPAKAKTIEKYLGGDFHVLASYGHIRDLPPKDGSVDPDNGFAMSWENYGDKGKQLKAIADEAKKATRLILATDPDREGEAISWHVQEVLRAKKALPQKVDRVTFNAITKQAVTEAMAQPRALDEDLIDAYRARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLVVEREREIESFVPQEYWSVAAEMEQAGQGFTARLVKWRGEKIERLTIGREGDAMAAKADVEAGRFTVEKVETKPVSRNPPPPFTTSTLQQEAARKLGFSASHTMRIAQQLYEDGAITYMRTDGVQMDGSAISAARKAIAERYDGGYLPEKPRQYQTKAKNAQEAHEAIRPTEFYRDKVGSGDHARLYDLIFKRALASQMASARLERTTVDLVDGTGQHGLRATGQVVIFPGFLALYEEGRDDPERGSGKHASADGEDDDSKLLPRMAAGDAPAKRKVTAEQHFTQPPPRYSEASLVKKLEELGIGRPSTYASTLQVLKDRDYVRIEKNRFFAEESGRLVTAFLERFFERYVSYDFTAGLEEELDDISGGRAQWQAVLEAFWRDFKPKTAEVMEQKPSDITAELDKFLEPMLFPPKADGSNPRACPMCGDGQLSLRGGRFGAFIACSNYPECKYTRKFGQPGGDKDGEDTGPEVLGQHPETGQDIVRKSGRFGPYIEMGEGKEAKRGSIPKDLPDGELTLDWAVKLLSLPREIGPHPETGKPIVANIGRFGPYLLHDGKYGRLSSTAEIFEVGMNSAVAKLADAANRGGRGASSREPLKVLGKHPRTEAEIKLMAGRYGPYVTDGTTNATLPKTIEQDALTLEEAAQLIDARAAAAPAKKGKKAVAKKAGAKKPAAKKAPAKKKVAAE
(1017) DNA topoisomerase 1 [Sphingopyxis alaskensis RB2256]
1
MQLVIVESPAKAKTIEKYLGRDFKVLASYGHVRDLPPKDGSVDPDDGFAMQWQLYPDKAKRLKEISDAAKGADRLILATDPDREGEAISWHVQELLRSKKALPAAVDRVTFNAITKQAVTDAMRHPRELDTDLIDAYRARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLVVEREREIEAFVAQQYWSVTGLFEMGGTPFKARLSRWRGDKIERLSITSEADARAAEADVKAGHFTVDTVETKPLTRNPPPPFTTSTLQQEAARKLGFSASHTMRIAQALYEDGAITYMRTDGVQMDGSAISAARKAIATRYDGGYVPDKPRQYQTKAKNAQEAHEAIRPTDFGKDKVGGGDHARLYELIWKRALASQMASARLERTSVELSDGTGKTTLRATGQVVKFPGFLALYDEGRDDAEDEDARLLPAMAKGDAPAKTGVEVERHETQPPPRYSEASLVKKMEELGIGRPSTYASILQVLKDRDYVRVEKNRFIPEESGRLLTAFLERFFERYVGYDFTAELEEELDDVSGGRAQWQAVLERFWRDFKPRTGEVMEQKPSEITAALDEFLGPYLFPDKSDGSDPRLCPNCGTGRLALRGGKFGPFIACSNYPDCKFTRKFAQSGGNGEADNGPETLGTDPESGLEVTKRSGRFGPYIQLGEGSEAKRSSIPKDIPAEDFDLDYALRLLSLPREVGVHPESGKPIMAGLGRYGPYLLHDGKYAKLGGTAEIFDIGMNAAVVRIAEAANGGGRGRAKAEPLNTFGPHPTSGGEMKLMEGRYGPYVTDGTTNATLPKTTDPATLTMEEAIALIDARAAKGPVKGKKKAAPKKKAAAKKAAAKEAPARKTAAE
(820) DNA topoisomerase 1 [Neorickettsia sennetsu str. Miyayama]
1
MNVLIVESPTKGKAIAQYLGKDFRVLSSFGHVRALPNKKGSVDVTESFEMLYKLTDTGETVVPQLIKDVKKATALYLATDPDREGEAISWHLVEVFKENDVLPKDVHRVVFHEITKTAVQNAIASPRKIDENLVRAQRLRQALDYLVGFSISPVLWKKLPGSKSAGRVQSVALRILCDRENEIGLFTPEEYWTVTVNMTDGEALVLPTQLSHMNGEKLERMSIRRAEEAEKIVEEISGLPFLVEEIKKKELKQKPSPPFITSTMQQTASTILGFSVKKTMSLAQKLYEGIEIGGVIEGLITYMRTDATHLSVESVDAIREFIQEKFGQEYLPASPVLFKKKVKNAQEAHEAIRPTSIFRTPEEIESYLTPDQYKLYRLIWERALACQMSDAITSSQNIVFVSQDKKFKTSASASLLIFDGFNAAFSHGKNKNKNQDVIDFIKKHKEGAQVKVGDVLLTQNFTEPPHRYSEAGLVKHLEELGIGRPSTYATVVSVLQERGYASIVNKSFIPESRGRLVSEFLVHFFSKYVEYHFTAELEDRLDKVADGTIFWLDVIQDFWDSFHSNVEEVEKVPITEVLAFVNGALARQKLVSAEVKVGDKCPKCEKGYMHLNVSRYGVFLGCTDYPVCRFIVNSYSTDNDTEYPKQIAQDISLHKGPYGIYLKCKGKNSSIPKDVDPVSIDEEFAHKIASLPKILGKHPIDGKEIKMGLGPYGLYLFWNAKYYNLQFSQMDEMTLDQAVQFMEDYVSHDKSLLRVLGSHEGEEIQIRDGRYGPYIKYSKMNVPIPKGESPESLSLETAILLIEKKKNTSKSARKVTTKRKVFTKEKK
(477) DNA topoisomerase 1 [Candidatus Midichloria mitochondrii IricVA]
1
MNLLIVESPAKAKTIGKYLGPSYKVISSYGHVRALPSEEGAVDPEHDFAMRYEIPPKAAKQIAAIVAEAKHSDHIYLATDPDREGEAISWHVLEILKQKKAIKNSTKVYRAVFHEITKKAIADSLKTPRDLNNDLVSAQKTRQGLDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRMICEREAEIESFKSQEYWSIHGRFSTEKGEEFDSTLIEFQGKKLEKFTTVNEAQAADVISKIKDNSFSVKRVEKKKVNRNPQAPFSTSTMIQEASRKLGFSAKKTAQIAQKLYEGININGELTGLITYMRTDSTSISAEATKAASELITKIYGSNYLPPSPRVYKTKTKNAQEAHEAIRPTDVFKKPESIKSFLEEDQFKLYELIWNRLVASQMASAILDVMTVDIADDQGNTFRATGSSIAFSGFYKVYREGIDDADEEKDRILPILKEKELLKLLEAIKEQHFTQPPPRYTEASLVKRMEELGIGRPSTYPTIISILQDRKYVIFEKKRFIPEPRGRLVNTFLTLFFNQYVEYGFTANLEEQLDEIAAGKVIWKKVMKDFWYPFKNKTDEVLSIKTSEILAKMEEQLLNYLFHKEILQDSKSIEEVLKCSKCVTGKLQLKNGRFGSFLACSNYPNCNYTKAIGSNDNNMQDTCNEPAVADLPKVLGTDPNTKEEVSIRKGPYGFYVQRGEGKKVKRTGLPKDLNYQNIDLNYAIGLLNMPRELGLDQEGVLIRAGAGKFGPYLERSGKYISLRTARIDPVLITLEEALGIIKKSSSDKKDKSSQGKRSAKATI
(796) DNA topoisomerase 1 [Novosphingobium sp. PP1Y]
1
MQLVIVESPAKAKTIEKYLGKDFKVLASYGHVRDLPPKDGSVRPDEGFEMDWELYGDKQKQVRAITDAAKVSDRLILATDPDREGEAISWHVLELLKKRRALPKDVQRVTFNAITKDTVTKAMQAPRELDQDLIDAYLARRALDYLFGFTLSPVLWRKLPGAKSAGRVQSVALRLIVDREREIEAFRPQEYWSVAAHMEQDGTPFTAKLVAFEGQKLDRLSLGDEGIAMRAKAAVEQGAFKVENVETKPHRRNPQPPFTTSTLQQEASRKLGFSASQTMRVAQSLYEAGAITYMRTDGVQMDPSAISACRKAISDRYDGHYLPEKPRHYETKAKNAQEAHEAIRPTEFTRDRFGSGDEARLYDLIFKRAMASQMASAALERTTITLRDGTGRNELRATGQVVKFPGFLAVYEEGRDQKDDDEESGLLPMMRSGDAPAKKDVTAEQHFTQPPPRFSEASLVKRLEELGIGRPSTYAATIQVLKDRNYVRTEKNRFFAEESGRLLTAFLERFFERYVAYDFTAGMEEELDDVSGGRHAWKELLEAFWRDFKPKSDEVMERKPSEVTEVLDEFLSDYLFPPKDDGSDPRACPKCADGRLALRGGRYGAFVACSNYPECKFTRKFAQPGGNGETADDEELGKHPETGEEITRRVGRFGPYIQLGEGKEAKRASIPKDIDELTLDWALKLLSLPREVGKHPETGKEIVANIGRYGPYLLHDGKYGKLRSTADVFETGMNAAVSILAEAAQGGGRGQRAKAEPIKVLGKHPTSEGEIKVLAGRYGPYVTDGTTNATLPRDQKPEELTAEQAIALIDAKAAKGPAKGKKKASAKKAPAKKATAKKAAGKSGEAKTATKKAPARKASVTKTSNDTSEQDGEVPWDVDA
(1221) DNA topoisomerase 1 [Sphingomonas wittichii RW1]
1
MKLVVVESPAKAKTIEKYLGPGHRVLASYGHVRDLPAKDGSVDPDNGFAMEWEAYADKSRQLKAIADEAKGADTLILATDPDREGEAISWHVKEVLGKRRVLPKDVRRVTFNAITKAAVTEAMANPRDLDEDLIDAYRARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVALRLVVDREREIELFKAQEYWSVTADMEYDGIGFLTRLVRWKGQKIDRLTIGNGKDAEAAKADVEAGRFTVASVETKPLTRNPPPPFTTSTLQQEAARKLGFSASHTMRIAQALYEDGAITYMRTDGVQMDGSAISAARGAIANRYDASYVPDKPRQYSAKAKNAQEAHEAIRPTDFSRDRAGSGDHGRLYDLIFKRALASQMASARLERTTVDLVDGTGQNALRATGQVVLFPGYLALYEEGRDDPNPQGQQAGGGDADEDSRRLPRMKEGDSPAKKKVDAEQHFTQPPPRYSEASLVKKMEELGIGRPSTYASILQTLKDRDYVTVEKNRFTPNESGRLVTSFLERFFERYVSYDYTAHLEEELDDVSGGRAGWQQVLEAFWKDFKPKTAEVMDQKPSEVTAALDEFLAPYLFPDKGDGTDPRLCPVCQEGRLSLRGGRFGAFIACSNYPECKFTRRFAQAGAANDGADTGPVVIGTDPATGLEVSKRAGRFGPYIQLGDGKDAKRSSIPKDVLGDDLDLGWALKLLSLPRLIGPHPETGHPITASIGRFGPYLAHDGKYARLGSTAEVFETGMNAAVVKLAEAANGGGRQRGKAEPLKTFGASPVTGSEVKLMAGRFGPYVTDGETNATLPKTANPDELTAEAALELLAARAAKGPPAKGKKKAPAKKAAPKKAAAKK
(419) DNA topoisomerase 1 [Brevundimonas subvibrioides ATCC 15264]
1
MNLVIVESPAKAKTINKYLGSGFEVLASYGHIRDLPSKDGSVKPDEDFAMEWEVDARASTRMTEIAAAAKRADRVILATDPDREGEAISWHVLEVLNKKKAIKDTPVERVTFNAITKSAVLEAMANPRQIDMELVEAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIVVDRELEIERFRPQEYWSIEADLAADSPPFTTRLVKHAGKRIQRLDIKDEATANAARDAIQTGDFTIRSIEKKPVRRFPSPPFTTSTLQQEASRKLGFDAQRTMRAAQKLYEGVDETGGLITYMRTDGVQTTPEGIAQAREVIGETFGPAFVPAEARYYKTKAKNAQEAHEAIRPTNIARRPDSLRLESDLQRLYELIWKRMVASQMEAARLDRTTVEVETPDGQTGLRATGQVVTFDGFLAVYEEGRDEKQKGAESEEDDDTARLPTLKEGAKAKVEAIRTDQHFTEPPPRYSEATLVKKLEELGIGRPSTYASILTTLRDREYVRMDKNRFIPEDNGRLVTAFLEQFFGRWVEYDFTAALENQLDEVSAGDMDWKALLREFWSKLKPATAAVLERQGVIDELDTAIGPFLFPEKADGSDARLCPLCKTGHLHLKASFKMKSSFIGCSNYPECRYTRGFGAGENAGDEAGGDRELGIDEATGLPVALKIGRFGPYVETANPGEEKPKRSSLPKGWSPATLTLEQAVRLLALPRPVGDHPEDGKPITAGLGRYGPFILHAGTYANVADIDEVFDIGLNRAVVLLAEKRAGKFAGRGAAVAPLKDLGAHPESGEPVHVMAGRFGPYVKSGKINATLPKGTAPEDMTMEIAVPLLAARALVAPKAKKAPAKKAAPKTAAAKKPAAAKKPAAKKPAAKKTKTVA
(1580) DNA topoisomerase [Parvibaculum lavamentivorans DS-1]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGSSKRGASRPRRSGRKGS
(46) DNA topoisomerase 1 [Parvibaculum lavamentivorans DS-1]
1
MDVVIVESPAKAKTINKYLGKGFKVLASYGHVRDLPSKDGSVLPDQDFAMAWDVDAKSQKRLNEIATAVKGADRLILATDPDREGEAISWHVLEVLNKKKVLKDVEVQRVVFNAITKKSVTEAMEHPRGLDKELIDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICDRELEIEAFRSQEYWTVEADMKTGGGSPFVARLTVLDGKKLDKFDIPDKKSADDIEARIKASRFSVKSVESKPTRRNPNPPFTTSTIQQEASRKLGFSASRTMQVAQRLYEGVEIDGETTGLITYMRTDGVQIAPEAIAQARTVINNEFGEAYLPDAPRVYTTKAKNAQEAHEAIRPTDLSRLPKHAAKYLDDDQRRLYELVWNRTIASQMESVQLERTTIEIEADDAPIGLRATGSVIVFDGFLRLYQEGRDEPDDGEDGGRLPKVARGDKLGLEKVRPEQHFTEPPPRFTEASIVKRMEELGIGRPSTYASTLQTLRDRDYVHMDKNRLVPQDKGRLVTAFLENFFTRYVEYDFTAELEEKLDKVSAGELDWKDLLREFWKEFTVNVAEALELRITEVLDRLNEVLGPHVFPEKEDGSNPRACPSCGNGILSLKVGRFGAFVGCSNYPDCKFTRQLTVGAEGEEQAGDRVLGTDPETGAEVSLKTGRFGPYVERAPLGDDEKPKRSGLPAKMSAADVDLDTALRLLTLPREIGIHPETGKKITAGLGRFGPFVLHDGTYANLKDPEELFDIGLNRAIAVLAEKVIRAEERAGKVLKELGDHPDTGKPVQVREGKYGPYIKHGTTNATLPKSADPAAVTLEEALALVAEKDAKSGKKKPAAKKAAKKPAAEKKPAAKKAPAKKPEKKKAPAKKKAPAKKPAAKARKTDKASELAD
(701) DNA topoisomerase 1 [Nitrobacter winogradskyi Nb-255]
1
MNIVIVESPAKAKTINKYLGTSYEVLASFGHVRDLPAKNGSVDPDANFQMIWEVDPKAAGRLNDIAKSLKGADKLILATDPDREGEAISWHVLEVLKQKRALKDQKIERVVFNAITKQAVTEAMKSPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLVTTLATPRGETFDARLVGADGKKIQRLDIGNGAEAEDFRKAIEAANFTVSTVEAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDVGGETTGLITYMRTDGVQIDGSAITQARKVIGEDYGHAYVPEAPRQYQTKAKNAQEAHEAIRPTDLSRRPSDMKRRLDADQARLYELIWIRTIASQMESAELERTTVDIAARAGARTLELRASGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSEGEALRRENLSVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLYGEDKGRVVIAFLENFFARYVEYDFTANLEEQLDRISNNEVSWQQVLKDFWDDFIGVVNEIKDVRVSEVLDVLDNMLGPHIYAPREDGGDPRQCPTCGTGRLNLKAGKFGAFVGCSNYPECRHTRPLAADGEAGGDRVLGKDPESGLDVAVKSGRFGPYIQLGEASDYGEGEKPKRAGIPKNTSPADIELDLAVKLLSLPREIGKHPETGEPITAGIGRFGPFVRHEKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKPLGDHPTLGPVAVKSGRYGAYVTAGGVNATIPSDKTQDTITLPEAIALIDERAAKGGGKPKRAAKKAKPAQTEKAGKDGAATKKPAKKAASKQASTKPKSEAVSKARGSIAAAKAPPNTVKAPTKKSAGKNG
(318) DNA topoisomerase 1 [Erythrobacter litoralis HTCC2594]
1
MQLVIVESPAKAKTIEKYLGKDFKVLASYGHVRDLPPKDGSVRPDEDFAMDWELYRDKQKRFKEISDAAKQADRLVLATDPDREGEAISWHVQELLAKRKALPAKVDRVTFNAITKSAVTEAMGRPRELDQPLIDAYLARRALDYLFGFTLSPVLWRKLPGAKSAGRVQSVALRLIVDREREIEAFKPEEYWSVLARFEHDGTEFDARMVRFDGKKLDKMTLGNEGSALAAKAAVDAGRFTVSDIETKPLKRNPAPPFTTSTLQQEAARKLGFSASHTMRCAQSLYEAGAITYMRTDGVQMDGSAIAACRHAIEERYESAYLPEKPRFYATKAKNAQEAHEAIRPTNFNRDSAGSGDEAKLYGLIFKRAMASQMATAQLERTTITLEDPTGQHALRATGQVVKFPGFFAVYQEGFDDKSDEDEDGLLPAMHKGDAPAKKGVEANQHFTQPPPRFSEASLVKRLEELGIGRPSTYASTIQTLRDRDYVRMEKNRFFAEESGRLLTAFLERFFPNYVAYEFTAGMEEELDTVSDGREEYKELLAKFWADFKPKADEVMEKLPSEVTEVLDDYLSDYLFPPTEDGTEPRACPLCRDEGREGGRLALRGGRYGAFVACANYPECKYTRRFAQPGGNESAADDGIMGQHPETGEDIERKSGRFGPYVQMGEGKEAKRASIPKDLDDFDLDWAVKLLDLPRIVGAHPETGKEIEAAIGRYGPYLRHDGKYGKLQSTRDVFEVGMNAAVTILAEAANRKGGGRGKAEPIKTLGEHPTSGGEMKVMPGRYGPYVTDGTTNATIPKDMKPEDVSEAQAIELIDARAAKGPVKKKRKKAPAKKKAAPKKKAAAKK
(1381) DNA topoisomerase 1 [Roseobacter litoralis Och 149]
1
MPVVVVESPAKAKTINSYLGDNYTVLASYGHVRDLPPKDGSVDPDAGFEMLWEVGYDSRKHVKAIADALKEDNALILATDPDREGEAISWHLQEALTKRKSIKKDTPVSRVVFNAITKAAVTEAMQNPRQVDMPLVEAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVTLRLIVEREMEIEAFRAREYWSVKALLATPRSQEFEARLTVLAGKKLDRFDIENQTQAELAVQAITSRDLSVKSVEAKPANRNPSAPFMTSTLQQEASRKFGMGARQTMSTAQRLYEAGYITYMRTDGIDMAPEAVSAARDAIKTLYGADYVPKSPRIYKNKAKNAQEAHECVRPTDMMTKAEDLKTSDADQRKLYDLIWKRTLACQMEAARLERTTAEIASEDGQIGLRATGQVMLFDGFLRVYEEGRDDVAVVDDDDKRLPQIGQGDRLDKRTVTPEQHFTQPPPRYTEATLVKRMEELGIGRPSTYASVVTTIQDREYVRKDKNRLIPEDKGRLVTAFLSNYFRKYVGYDFTADLEDQLDTVSAGNADYKEVLGRFWRDFSAAIAETADLRITEVLEKINEVLEPHLFPANEDGTDPRLCPNCGAGRLSMRTARSGGAFIGCSNYPECRYTRAFGPPGEEDDSGIPPEGKLLGEDGEDKIYAFKGRFGPYVQRGEVTEDNKKPPRQSIPKDWPPEDVDLPQALKLLSLPREIGPHPEDGITVWANIGRYGPYIKHAPSTSDRGGTNANLEGIDEVFTVGMNRAVQLLAEKLASRGQRGGAAKTLRDLGEHPEEGGPIAIMEGKYGPYVKWEKVNATLPKDSDPAGLTMEAAVALIDEKAASKGKKRRKAAPKKTAAKKTATKKAAPKKTAPKKKAQAKKAEE
(554) DNA topoisomerase 1 [Jannaschia sp. CCS1]
1
MPVVVVESPAKAKTINKYLGSDYTVLASYGHVRDLPSKDGSVDPEEGFFMKWEIGSDSKKHVKAIVDALKDDNSLILATDPDREGEAISWHLQEALTSRKAIKTDTPVSRVTFNAITKDAVTKAMAEPRQVDMELVEAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVCLRLVVEREMEIEAFRPREYWSVRAVLETPRGQTIEARLTVLGGKKLDRYDLPSAAEAGLAVQAVSSRKLSVSDVEAKPANRNPSPPFMTSTLQQEASRKLGMGAKQAMSTAQRLYEAGHITYMRTDGIDMAPEAVEDARGAIKTRYGVDYVPGKPRIYKNKAKNAQEAHECVRPTDMSKAANDLKLSEDDQRKLYDLIWKRTIASQMEAARLERTTVTIASDDREVELRATGQVMLFDGFLKVYEEGRDDAGDDEDSKRLPQVSAGDPLKPSADAMADDYAKYSGDDVVEDDGNGDVRRSKSAILSREGAVLGQQHHTAPPPRYTEATLVKRMEELGIGRPSTYASIMDTIQNRGYVIKDKGRLIPEDKGRLVTVFLSNYFNRYVQYDFTADLEQQLDEVSAGDRHYKDVLDRFWRDFRAAIDETSDLRIGEVLDKINEVLEPHLFPDPGDGTDPRLCPNCGVGRLSMRTARAGGAFIGCSAYPECRYTRPFGPPDPEAEASAIPPDGKLLGEDQGDEIRIFKGRFGPYVQRGAMTEENKKPPRQSIPKDWTPEELDLERALMLLSLPRQIGPHPEDGIMVWSNIGRYGPYLKHAESTSDRGGTNANLDGLDEVFTVGMNRAVQLLAEKVASRGGRGQAAKPLRELGEHPDAGGPVNVMKGKYGPYVKWDKVNATIPEAIDPEAITMDQAVQLIEERAAKSGKKKPAAKKKTTAKKPAAKKKPAAKKTAKSAD
(1792) DNA topoisomerase 1 [Mesorhizobium loti MAFF303099]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAAILGTPRNETFEARLTAFERKKLQKLDIANKAQADDIKAMLEGATFKALSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSATRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRFYTTKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAIASQMQPAEIERTTVEIEAVNGARTAELRAVGSVVRFDGFIAAYTDQKDDDAEDEENRRLPEIRAGEQLARQAINATQHTTEPPPRYSEATLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFERYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGDDGTKVLGKDPYTAEEITLRSGRFGPYLQRGDGKDAKRSSLPKGWTPETIDHEKALALLALPRDIGKHPETSKMISAGLGRYGPFVLHDGTYANLDSIEDVFSIGLNRAVTVIAEKQSKGKGGRNGGTPAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTIEDALALIAEKEAKGGGGKKPFRKAAAAKAPAAKKTAARKPAAKKKG
(1539) DNA topoisomerase 1 [Bartonella henselae str. Houston-1]
1
MNIVIVESPAKAKTINKYLGSQYKVVASFGHVRDLPAKDGSVLPDQDFSMKWDVDSAAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPVKRVVFNAITKKSVLDAMNNPRDIDTSLVNAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTDLKTIRNDGFQARLTMFNQKKIGKLDIQSQEQADQIRLMLEKAKYHALSVEAKPTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGEMAGLITYMRTDGVQIAPEAIDSARKVIHESFGSDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRIPNQVRNFLDSDQAKLYELIWKRAVASQMRSAEIERTTVEIEAQQGENYANLRATGSVIRFDGFLSLYTDQRDEENNEENETTRLPQINTGEELTKEKVDAIQHTTEPPPRYSEASLIKKLEELGIGRPSTYASTLATLSDRGYIIIDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNASITNIQELRITNVLDVLNVTLAPLAFPVREDGSDVRSCPLCTNGQLSLKLGRYGAFVGCSNYPECKYTRQLGTDPGEENEAIRNDEPVILGVDPKTGKDVTLRNGRFGPYIQLGESKEAKRAGLPKEWQAEKITLEKALSLISLPREIGIHPETGKTITATIGRYGPYLTHDGKYAPLLNVDEVFDIGINRAVTVLAEKQENKTKRSRTTTAALATLGNHPDGGVVTVRNGRYGPYVNWGKVNATLPKDKDPINVTLSEALELISVKASGKKTTLKRASTKTKET
(540) DNA topoisomerase 1 [Beijerinckia indica subsp. indica ATCC 9039]
1
MNVVIVESPAKAKTINKYLGKDYEVFASFGHVRDLPPKDGSVDPDHDFAMLWDVDTKSAKRLADIAKAVKEADRVILATDPDREGEAISWHVLEVLKAKKVLKDKPVERVVFNAITQSAILDAMRHPRAIDIDLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCERELEIERFVPREYWSLTAFLRTPADQPFSAKLVGADGKKINRLDIGAGAEAEAFKAALETAKFTVAKVEAKPARRNPAPPFTTSTLQQEAARKLGLAPARTMQLAQRLYEGIDLDGETVGLITYMRTDGVDLAPEAITGARKVIAAEYGDKYVPQAPRRYQVKAKNAQEAHEAIRPTDLARLPKHVARFLDAEQARLYDLIWTRTIASQMESAELERTTVDILAEVGARRLDLRATGQVVRFDGFLKLYQEGRDDEEDEEGGRLPAMQVGDPLKKDRIEASQHFTEPPPRFTEATLVKRMEELGIGRPSTYASTLAVLKDREYVRIDKKRLIPEDKGRLVTAFLESFFGRYVGYDFTADLESSLDKISNHEIDWKQVLRDFWADFSGAIADTKDLRTTQVLDSLNEVLGPYIFPDKGDGSNPRACPSCANGQLSLKLGKFGSFIGCSNYPECKFTRTLSDTGPEGGNGETDRPGVKVLGVDAETGEEISLRDGRFGAYVQRGEGEKPKRASLPKTIAPADLTLDMALGLLSLPREVARHPETHEPILAGIGRFGPYVQHGKTYANIGKDEDILTLGANRAIDLIIAKESGLTGRRFGKGESAPARVLGDHPEGGQVTIKAGRFGPYVNYGKLNATLPKDADPTTLTLEEGLALLAAKASGQGGGKGAVQGQLLGEHPSGGPITVREGRFGPYVNHGKVNATLKSGLSPETLTLEEAIRLIDEKAGAASKKAPAKKAPAKKASGKTTTTEKAPAKKAASKAATAKTTKAKAAKSSEPDEEPPF
(1206) DNA topoisomerase 1 [Rhizobium leguminosarum bv. viciae 3841]
1
MNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDSASAKRMKDIADALKSSDGLILATDPDREGEAISWHVLDMLNKKRALTGKSVKRVVFNAITKKAVLDAMAAPRDLDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNISALLKTPRGDEFEAKLVSASGKRLQPRAIGNGEDAGRLKALLEGASYVVDSVEAKPVKRNPGPPFTTSTLQQAASSNLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARSAIVDQFGERYMPEKPRFYSTKAKNAQEAHEAIRPTDFDRSPDRVRKFLDADQIRLYELIWKRGIASQMASAEIERTTAEITADNKGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDEDGRLPEINAREALAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLIPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKQVLRDFWKDFFAQIEDTKELRVTNVLDSLNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPDCNYTRQLSSENGGEADGAALNEPKNLGTDPTTGEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGKHPESGKMISSGIGRYGPFLLHDGSYANLETVEDVFSVGLNRAVTVIAEKAKQAPGRGARGTPAALKTLGDHPDGGAITVRDGKYGPYVNWGKVNATLPKGKDPQAITVEEALALIAEKAGKAPASKTAKAKAKPKAAAAAAKSTKTAAKPKATKAKAPAKSKKG
(1817) DNA topoisomerase 1 [Sinorhizobium meliloti 1021]
1
MFQRMSMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLRKKKVIGDKPVKRVVFNAITKKAVLDAMAEPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPPKAIGNGEEANRLKSLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFDRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLVPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAAANEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPAAIDHEKALALLSLPRDIGPHPESGKMISTGIGRYGPFVLHNGTYANLESVEDVFSIGLNRAISVLADKQSKGAGGGRASAAALKELGEHPDGGAITVRDGRFGPYVNWGKVNATLPRGKDPQSVTVEEALALIAEREAKGGVTKGKAAKGKPTGGKSAGTKSAKAASAGTAKAEKPKSAAKTKTKAAAKAKKD
(1560) DNA topoisomerase 1 [Brucella abortus A13334]
1
MGREFRLLYMNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEILRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGRDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEQITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(86) DNA topoisomerase 1 [Brucella ovis ATCC 25840]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKTVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAITKSFSAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFAGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(618) DNA topoisomerase 1 [Ruegeria pomeroyi DSS-3]
1
MPVVVVESPAKAKTINKYLGSDYTVLASYGHVRDLPAKDGSVDPEHDFDMTWEVAADSRKHVKAIADALAEDNELILATDPDREGEAISWHLQEALTKRRSIKKGTAVSRVTFNAITKDAVTKAMQNPRQVDMPLVEAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVCLRLIVEREMEIEAFKPVEYWSVKALLETPRGQVYEARLVTLAGNKLDKMDISNATQAELAVQAITSRALSIQSVEAKPAARNPSAPFMTSTLQQEASRKFGMGARHCMSAAQRLYEAGHITYMRTDGIDMAPEAVMATRDAIADRFGAEYVPDSPRMYKNKAKNAQEAHECIRPTDMRKDAAALKLKDEDQRRLYDLIWKRTIACQMAAARLERTTVEIGSADGQVGLRATGQVVLFDGFLRVYEEGRDDVENDEDKRLPQISMGEKAVFAKTSLADQFARATGDTPLTEGAKIAKEAILSENEAVLALQHHTQPPPRYTEATLVKRMEELGIGRPSTYASVITTIQDREYVRKDKNRLIPEEKGRIVTIFLLNFFRQYVGYEFTANLEEQLDDVSAGSRDYKDLLGRFWRDFSAAISETSELRISEVLDKLDEALAPQLYPPREDGSDPRICPKCGTGQLHLKTSRTGGFVGCGNYPECRYTRPISGDADDSAERLLGEDGGDEIWLKAGRFGPYVQRGEISEENKKPPRASLPRGWSAEDLDLEKALVLLSLPRQIGQHPEGGMISSNFGRFGPYLMHQLPDEAKPIYANLKDPSDVFEIGMNRAVELLAEKRANPRGRGRAAAKPLKELGEHPEHGGAVNVLDGRYGAYIKWDKVNATLPKDVEAADVTMEMAVALIAEKSTKKGTKKKAAPRKKTTKKAAEE
(162) DNA topoisomerase 1 [Candidatus Pelagibacter ubique HTCC1062]
1
MNLVVVESPAKAKTINKYLGDDYIVLASYGHIRDLPSKNGSVDPENNFKMEWEVDSFSKKYLKEITDAAKISSKIILATDPDREGEAIAWHVKEYLNEKKLIKDKHIERVVFNEITKKAVIHGIENPRQIEPLLVDAYMARRALDYLVGFNISPILWTKLPGSKSAGRVQSVALKLITEREHEIELFDPEEFWTLSIQFNDSNKNSILASITQLNDKKIEKFSFKNKAEIDKAMKEVKSKNFNINDISSKVVNRNPSGPFTTSTLQQVSSGRLGFGASRTMQIAQKLYQGIEIDGETIGLITYMRTDGTNLSTDAIDTFRKYIKNEFGDEYVPDNAASYSGKKAKNAQEAHEAIRPTDIMRAPDTVKKYLSPDQHKLYDLIWSRALSSQMKPAQFDRNTITITSDDNGTICKASGSVIKFDGFLKVMKDTKKDDDEDILPEMNKGPVNIESLLDEQHFTQPPPRYSEASLVKKLEELGIGRPSTYASIISVISTRGYAETINKRFHPTDRGKLISAFLEKLFSKYVDYNFTASLENQLDDITTGKEGWIKVLELFWKDFNQNVSDVKEKRTREVLDLLNDSLGSLIFERDTEGNINRQCKLCNGGSLSLKNSFRGGAFIGCSNYPDCKFTRPLSKAKAAAQSQLAEPKFIGKHENGNDMYLKNGRFGPYLQYEKIEEIKDEIIIETKKKKKTKKKKIEKEDNNLRNVSIPKGITLDSVDLDRAKFLCSLPKSLGINPENQRDIILNSGRFGPYLKCENKSARIENVEEIFSIGLNRAITLIAEAKPGRMSASIIKDLGEHPEDKKPVRVMKGQYGPYIKYKSLNATIPEEKDPLELNMEEALILIEKRKEYDKNKKVKKKKKK
(1884) DNA topoisomerase 1 [Anaplasma marginale str. St. Maries]
1
MGVVIVESPSKAKTISKYLGGKYKVVASFGHVRDFPAKSGSVDPDDDFRMIYEIIPKSEKYIDKIVKTVSSEKSGIYLATDPDREGEAIAWHIVEVLRERSAIGEDVAVNRMVFNEVTKRAVNAAINDCRSINMDLVHAQQARRVLDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLICEREHEIEQFDSKEYWDIEVLLKNNSGEKLTATLKHYNGEKLDKFAIPDADSANAIAEHVRNGTYHVASVEAKQTKRNPYPPFITSSLQQEASTKLGFSAKNTMMVAQKLYEGVDIGGETVGLITYMRTDGFYISTEAISYIRDTIKMQFGDKYLTKSPRQYVKKVKNAQEAHEAIRPTDITMTPDSLAKYLSDDQLKLYDLIWRRTMASQMESAVIDQVIVDIQSKDGSVVLHAVGSSLGFDGYQKVYGTDDDDKRKMLPQLKVGEACNLVEVSPNQHFTQPPPRYSEASLVKKMEEIGIGRPSTYAAIISVLQERGYTQLEQKKFVPSERGRIVNAFLTNFFSRYVEYDFTANLEEELDLISNGNMAWKEVLRRFWHKFISDVSTVKGIEVSEILKSITKDLEGYAFSSSSGEVVDRSCPGCGEGELMLNIGKYKAFLGCNRYPECKYTRGIGGESGVCRDEFPKVLGLDDATQEEIVLKNGPYGEYLQLGDNAQGKRVAVPQGIQEITLDVAKKLLSLPIVLGNYPDTAQDIKLGTGRFGPYVLYGGTYFSVKGREDFWNLTLEEAVDVINSQAQKKSRLLGLHDNGKEIYVCKGRYGFYLKCGDKNVAIKGKSDDITLEEAVSLLNQKA
(1297) DNA topoisomerase 1 [Rickettsia canadensis str. McKiel]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAIKYDISDKASKYVDAIVKDAQKADAVYLATDPDREGESISWHVAEVIKEKNKVKAADFFKRVAFNEITQKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKAEEYWDISLKMQNSNNELFTAKLTHINNQKLERFSITNKKDAKDLTKKLKSQNFHIDQIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAVADIRKLIDKNYGDKYLPSSPRIYKSTVKNAQEAHEAIRPTNITYTPDSLKEKLAKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPLLKENEQLNTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYATILSVLQDRKYVSLKKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKSALSNFWSGFNHNIKSVNEQKITEIISYVQKALDYHLFGENQESKACPSCKTGELSLKLGKFGAFLACNNYPKCTFRKSIVSGNNNNENEDKLSTTPNEENKVLGTDKDGIEIYLKKGPYGPYIQRGEHEGTVKLKRSPVPASLNQSDITLDIALKLLSLPLKIGTHKDTHEEIMIGYGKFGPYIKYIGKFISIPKKYDFLNLSLDEAIQLIEDNKTKLEKKQA
(1053) DNA topoisomerase 1 [Rickettsia prowazekii str. Madrid E]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDKNFLMEYDISDKAGKYVDAIVKEARKAEVVYLATDPDREGESISWHVAEVIKEKNKVESDDFFKRVAFNEITKKAIMNAVANPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICDREDEIERFKSEEYWDISLKMQNSNNDLFTAKLTHVNDQKLKKFSIINEKEAKDLTQKLKLQKFYVEKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGNQYLPIKPRIYQSKVKNAQEAHEAIRPTNITYTPDSLKQKLEKDYYKLYELIWHRTIACQMENVIMDLVIANLASENKEYLAKANGSIIAFDGFYKVYRESLDDEDEEDNKMLPPLKEQEHIKTKEVIPNKHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKTALNNFWRGFNHNIESVNEQKITEIINYLQKALDYHLFGEDKESKVCPSCKTGQLSLKLGKFGAFLACSNYPECTFKKSIVSGNDNNEDEGDPSTILNDNKILGTDQDGVEIYLKKGPYGPYIQLGEQCGKVKPKRTPVPANLKQSEITLEIALKLLNLPLKIGIHKDSGEEIIIGYSKFGPYIKYMCKFISVPKKYDFLNLSLNDAMKLIQNNKAKLEKKYG
(113) DNA topoisomerase III [Azospirillum brasilense Sp245]
3
MAVMATLIITEKSSQAKDLRAALGDRYGRILPAEGHLLRLAEPDEVNPDWKRWSPTLLKPDGLYPTKPDSGGNKTAKLAAIKAALKGCDQVILATDCDREGQLIGQEILEHLGFRGRVQRALFTAQDPKTIRDAFAKLKPNNELRPLYEAAVARQQADQIFNLSLTRTATKTLLAPGTRGVIGIGRVKTPTLSIVCLRELEIRNFKPEDYFEVVATATAAGGSFLMRHAPPPKDRIKDRARAEAIARAADGHGGPLSVTVEDRRQAPPKLYDLPALQKTCGQRWGWTADRTLEVAQELYDGEGKKLITYPRAEARYLSENQIADVPAIAGALTRLRGFAHLDISRPVIRRGKSGHFCDKALEGVSHHAIVPNVNVLDDLESRLNRLTDDEKRLYALICRSYLAAVMPDYEYRQTTVLMNVPVEGKPVVFRAVGRIPLKLGWKAAFGSAETDGKPDEKEEEQTLPPLTDGEPARLSEPRVEAKRTQAPPRYNEGTLVDAMQNAWRFVEDLALRDRLKEAKGIGTPATRAEIIKGLRRQNLLGADGKWLVPTPAGLQLFETLRGAAPTLVDPGTTALWEMRLDEVVVGRADFRSVIDGIADEAERLIGVLVGNQGSAVDLGVRGGPIRAGRGAGRRRSTSPRAAGAPPRPRTRKAAAAAVGVDGEAPKTPRRSRKAKAAPEVPGSIGPVADAVPPSPAAPSIGARRKAPTDKMVAFARSLADRKGVELSDTVLQDFDSCRQFLDQHAR
(1427) DNA topoisomerase 1 [Ehrlichia chaffeensis str. Arkansas]
1
MSLIIVESPSKAKTISKYLGSKYKVVASFGHIRDFPAKSGSVDPDKDFAMTYEIISKSEKYVNKLIQVANKETQGIYLATDPDREGEAIAWHIIEVLKENNAIDDNVVINRMVFNEVTKSAILESIKRPRSINMDLVYAQQARRALDYLVGFTLSPLLWRKLPGSKSAGRVQSVALRLICDRESDIEKFITQEYWDIEAKCCNTEGKQFSAFLSCYAGKKLEKFDIKNEEDAQKLSEEVRSRSYSVINVEKKHTKRNPYPPFITSSLQQEASTKLGFTAKNTMLIAQKLYEGIDVGGEIVGLITYMRTDGFYIADEALEHIRSIIVSMFGKEYLPESARKYVKKVKNAQEAHEAIRPTNITITPGSLSNYLTPEQLKLYDLIWKRTVASQMNSAVIDQVIVELGSLDKVVTLRATGSSLFFDGFYKVYGHGEDDDSKNNMLPLLQKNDKCPLDEVVPHQHFTNPPARYNEASLVKKMEEIGIGRPSTYASIISVLQDRQYVILNQKRFFPTERGRIVNVFLVNFFSRYVEYDFTADLEEKLDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRVCPVCNDGTLELNISKNGIFLGCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQEIYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAEKILSLPISLGTHPDTGQEIKLGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFLCKGRYGFYLKYDKLNVALKKDTDIEQISLSDAIKLISEKL
(1085) DNA topoisomerase 1 [Dinoroseobacter shibae DFL 12 = DSM 16493]
1
MPVVVVESPAKAKTINKYLGSDFTVLASYGHVRDLPPKDGSVDPEHGFEMLWEIASDSRKHVKAIADALKDDDTLILATDPDREGEAISWHLQEALTKRKAIKKSTDVSRVVFNAITKSAVTEAMKNPRDVDMELVEAYLARRALDYLVGFNLSPVLWRKLPGAKSAGRVQSVCLRLIVEREMEIEAFDPREYWSVRAVLETPRGQTYEARLTELAGKKLDKFDLATAEAAELAVQAVTSRKLSVTSVEAKPGTRNPSAPFMTSTLQQEASRKFGFGARQTMSTAQRLYEAGYITYMRTDGIDMAPEAVTMARDAIKERFGAAYLPDSPRIYKNKAKNAQEAHECIRPTEMSRAPEDLKVTEPDQRKLYDLIWKRTLASQMAAARLERTTVEIGSPDGQVALRATGQVVVFDGFMKVYTEGQDEESTAEDERRLPQIGQGDPAPLHKGGMEAAFAKAGSREDDVVEAAPTGGMQQGPGGLLSENGAVFGQQHFTQPPPRYTEATLVKRMEELGIGRPSTYASIVTTIQDRGYVTKDKNRLIPEDKGRLVTAFLVNYFRKYVGYDFTADLENQLDEVSAGDRNYKDVLDRFWRDFSAAIAETSELRITEVLEKINEVLAPHLFPPREDGKPPRLCPNCEIGQLSMRTARSGGAFIGCSNYPECRYTRPFGPPGMEEASGIPPEGKLLGEDGGDEIRVFKGRFGPYVQRGAVTEENKKPPRQSIPKSWVPEELELDKAVMLLSLPRQIGLHPDDGVPVWANIGRYGPYLKHADSTSDRGGTNANLEDIEEVWTVGMNRAVQLLAEKVASRGGRGAAAKPLRELGEHPEAGGPVNIMKGKYGPYVKWEKINATIPKETDPEQVTMEMAVQLIEERAAKSGKKAPAKKKAATKKKTAAKKTSAK
(1055) DNA topoisomerase 1 [Methylobacterium extorquens AM1]
1
MKVVVVESPAKAKTINKYLGRDYEVLASFGHIRDLPAKDGSVDPEADFAMIWEVEDRGAKRVSEIARAVKGAEKLILATDPDREGEAISWHVIEALTARKALKGIPVERVTFNAITKASVDAAMKKPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWSIIATLVTEAGGVFEARLVGADGKRIQRLDVGNAEEAAAFKRDLELATFQVASIEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQRLYEGVDVGGETVGIITYMRTDGVDMAPEAIQDARQVIGREFGDAYVPSAPRKYTVKAKNAQEAHEAVRPTDMGRLPKHVARHLEPEQAKLYDLIWTRTIASQMESAELERTTVEVSANVGPRRIDLRATGQVVKFDGFLALYQEGKDDEEDEDAKRLPAMKAGDALKRERIASTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVRIEKKRLQPEDKGRLVTGFLESFFKRYVEYDFTASLEEQLDRVSNAEIDWRSVLRDFWRDFSAAIGGTKELRVAEVLEALNGLLGPHIFPEKADGGDPRACPTCGAGQLSLKLGKFGAFIGCSNYPECKYTRQLSASGVEGEGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFVQLGEASAEKGAEKPKRSSLPKGTTPGSVTLEIALRLLSLPREVAKHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRPSSDPGRTLGQHPDGAALVVKAGKYGPYVSDGSVNATLPKTMAAESLTLEQAIDLVNAKRASGGGKKPVRKTASRARAPAKKAEAGEAKKPAVRKTAAKPAAKATATKAAAKPAAAKKATAKTKAG
(531) DNA topoisomerase [Methylobacterium extorquens AM1]
3
MPQRLFIAEKPALGRAIATALATLSGARPSAGRGFIEVGGDCVTWTIGHAYDTAEPGDYSSTWDKWSLDVLPMLPERWKLVPNAEIADQIAVLKDRIRRYDHFVNVGDAEREGQLIVDEILIENGVDPFSPKVSRVWVSSFVEKDVAAAVAGAFPNSQKKSLYEAAVARQRADWLLGMNMSRVFGLMVQQSGARGFRVSVGRVQTPTLKLVVDRDWQIENFKAVDHFAPSITFVHENGTFKAAWQFPADTKGLDPEGRLLDKAVAQALVQKIAGKTGTVESYSETPKSTSPPLPFALSTLQKACSQKFGLTAQQTLDVAQELYEKHKAITYPRSDSQHLPNSVHTDEADGILRNLAGVRELADAAGRANPKLKSPAFDDKKVTDHHGIIPTSEASASKLAAMGEIERKVFLLIARTFVAQFHPDFRYVSSAATVLCEGERFKATGTRVVDQGWKTVFGAEEADEEEEAEGTLPSMKMKDPVDAKAGSIDPKRTKPPAHFDDGTLVEAMAKIHLYVQDQEVRKRLRENDGIGTEATRASMIEKLIRAKYLERRTKGKRKILVSTDAGRQLVDLLPSDLVAPDTTAMWESFLERVKGGEFTLAQFMDRQTQFVRKRVQTAIAAGAIQVKGFSVEPLEGHGTECPHCRAGHLVTQLWPFDDEYKGRRFLRCDNWVKDRADNCRYKTPPEGYKEREKLEGEGNPCPACGKGVLKGGVVRKEGPNRGRPFLMCSEVDREKPDSCQHFEWKDETPCPSCGKGVLKRGVVRKEGPNKGRPFAMCSAVDRTNPDGCQHFSWLDEKAAKGPKIKGEGELCTVCGKGTMMRRTGRTSGKPFLSCSNWKQGASDSCDNRVFPDDGGRRPAGGASAAPAARPRGGRPSPGGGKRSFAKAR
(883) Putative DNA topoisomerase [Methylobacterium extorquens AM1]
3
MADLFVIEAPFKAQLLEGILRELHVDAKVQATRGHFMSMPGKLRPLGIDCRMREFMRVPANPEVFMRLRDMARSADNLYIATDADQEGDVIAWDVYEAVRDIHPSPARVRLKSMDHASIREAIAAAGPVEKAAAVPGRARGIIDRMIGGVFGSPEVPAGRVSTAILGLVASRGLSVTKVRLAAPSKDRGRPWLAEFDLAAPLDLPTAERLAKLDLPPLGSRGSPVVHPTKPSHTGDILVRAGDRLDISPAEAAASLQRSYEAGRMSYPRAGSRGMTPETAKQIAGIFRKSGWTAVKTENFAAKGEDETHEAPHPIGAVDPRLNPGRLGQDEGVRTLVAADLVKAGMEHKRETAFAQDLAPFLRAQGLPGEVADFVAGLRPGRDGATLTWHREHGPAYPGQEVWARSGIERRRPDTVLLEAVVKAGLGRPSTWPRHVQTFMDRGLADDDLKLTPRGRAWVEGSYAPLLDPRLSAAIEVACERVDPSLFDDPDREPWEVMVDQIVNLLPPSVRDPLREAVAHEPPRQKIDWVGKLDARPDLVGRLAQYVSRPEYAPDL
(447) DNA topoisomerase 1 [Rickettsia massiliae MTU5]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQTLEKFSIINEKNAKDLIEKLKSQKFHVDKIEKKQQKRQPQPPFITSSLQQDAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMNLVVANLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKVCTSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGEQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMVGYGKFGPYIKYMGKFIAVQKKYDFLNLSLDDAMKLIEENKEKLEKKQA
(1142) DNA topoisomerase 1 [Agrobacterium radiobacter K84]
1
MMNVVVVESPAKAKTINKYLGPGYTVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDPASQKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLNKKRVINGKPVKRVVFNAITKKAVLDAMADPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNLSAILKTPRGDEFEARLVAANGKRLQPRAIGNGEEAGNLKALLEGASYVVDTVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARTAIADQFGNRYLPEKARLYSTKAKNAQEAHEAIRPTDFDRTPDRVRKYLDADQLRLYDLVWKRGIASQMASAEIERTTVEILADNGGQKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDADDEDGRLPEINARENLAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLLPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKDVLRDFWRDFFAQIEDTKELRVTNVLDALNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNYTRQLSSEGGTEAEASGLNEPKALGTDPVTNEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGKHPESGKMISSGIGRYGPFLLHDGSYANLETVEDVFTVGLNRAVTVLAEKQSKAGGGRGTPAALKDLGAHPDGGGSITVRDGKYGPYVNWGKVNATLPKGSDPQAITVEEALALIVAKAGKSGGGKPARAPAKAKTKTAAAASKTTKTTAKPKAKAATKAKTTKKSAE
(1428) DNA topoisomerase 1 [Rhodobacter sphaeroides 2.4.1]
1
MAVVVVESPAKAKTINKYLGSDYTVLASYGHVRDLPPKDGSVDPEHEFAMTWEVAADSKKHVRAIADALKTDDTLILATDPDREGEAISWHLQEALASSLKKGKTVRRVTFNAITKSAVTEAMKAPREVDTALVEAYLARRALDYLVGFTLSPVLWRKLPGAKSAGRVQSVCLRLIVEREMEIEAFRAREFWTVSAVLATPRGQEFEARLTVLGGKKLEKFDLATSEAAELAVQAVTSRPLKVASVEAKPASRNPSAPFMTSTLQQEASRKFGMGAKQCMSAAQRLYEAGHITYMRTDGIDMAPEAVMAARDEIKRRFGANYVPDSPRMYKNKAKNAQEAHECIRPTDMSASPEKLGLTDTDQRKLYELIWKRTLASQMAAARLERTTVEIASPDGQVGLRATGQVVLFDGFLKVYEEGRDDRSDGDEDDEGRLPQIMANEAVEKKSITPEQHHTQPPPRYTEATLVKRMEELGIGRPSTYASIVSTIQDREYVRKDKNRLIPEDKGRLVTAFLANFFRKYVEYDFTADLEGELDDVSAGERNYKEVLARFWRDFSAAVAETADLRIGEVLDKLDEFLAPHLYPPRPDGSDPRICPTCGSGRLHLKTARGGGAFIGCGNYPDCRYTRPISVTGDEENAISPDGKLLGHDEDGAPISLRSGRFGPYVQKGEVTAEVPKPPRASLPKGWAPDTVDLDRALMLLNLPRLVGSHPEDGQPVEAAIGRYGPYVKHGSTYANLPDVEEVFTIGMNRAVEVLAQKAAGRRGASAPAQPIKELGEHPDGGLLAVMPGRYGPYVKWGKVNATIPKGIEPEAITLEEALALVAEKAGKAPKKKAPARKAKAEEGAPKKAAPKKAAAKTTKTAAKKPAAAKSTAKKKAAPDTDAA
(1542) DNA topoisomerase 1 [Bartonella grahamii as4aup]
1
MNIVIVESPAKAKTINKYLGSQYKVVASFGHVRDLPAKDGSVLPDRDFSMKWDIDSSAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPIKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSVTTQLKTIRNDSFQARLTMFNQRKIGKLDIQSQEQADQIRFMLEKSQYHTLSVEAKPTKRNPLPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGETAGLITYMRTDGVQIAPEAIDSARKVIHETFGKDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRNPSQVRNFLDSDQAKLYELIWKRAIASQMRSAEIERTTVEIEAQQGENRANLRATGSVIRFDGFISVYTDQRDEENNEENETTRLPQVNTGEALTKEKVESVQHTTEPPSRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIVIDKRKLIPDAKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNASISNIQELRITNVLDVLNVTLAPLAFPEREDGSDVRSCPLCKNGQLSLKLGRYGAFVGCSNYPECKYTHQLGTDTGEENEAVRNDEPVILGIDPETGKDISLRNGRFGPYIQLGESKEVKRAGLPKEWQAENVTLDKALALLSLPREIGVHPESGKTITATIGRYGPYLSHNGKSARLLHADEVFDIGINRAVTVLAEQQENKTKQSRATPAALAILGEHPEGGTITVRNGRYGPYVNWGKINATLPKDKDPISVTLPEALELISAKASSKKTTSKRASSKTKAKIKET
(1097) DNA topoisomerase 1 [Rickettsia felis URRWXCal2]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVENPRKLDANLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFSENKESKACPSCKTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENDGDLAATPNENKVLGTDKDGIEIYLKKGPYGPYVQLGEQEGKVKPKRSPVPASLNQNDITLEMALKLLSLPLKIGIHKDSGEEIMIGYGKFGPYIKYMGKFISIPKKYDFLNLSLDDAMKLIEDNKAKLEKKQA
(1755) DNA topoisomerase 1 [Rickettsia endosymbiont of Ixodes scapularis]
1
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFYVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNVQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVCRESVDDEAEEENKMLPPLKEQEPLKTKEVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALSNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKVCPSCKTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPSAIPNENKVLGTNKDGVEIYLKKGPYGPYIQLGEQEGKVKPKRSPVPANLNQNDITLDIALKLLSLPLKIGVPKDSGEEIMIGYGKFGPYIKYMGKFISVPKKYDFLNLRLDDAMKLIEDNKRS
(719) DNA topoisomerase 1 [Neorickettsia risticii str. Illinois]
1
MNVLIVESPTKGKAIAQYLGKDFRVLSSFGHVRALPNKKGSVDVTDSFEMLYKLTDTGETVVPQLIKDVKNATALYLATDPDREGEAISWHLVEVFKENDVLPKNVHRVVFHEITKTAVQNAIASPRKIDENLVRAQRLRQALDYLVGFSISPVLWKKLPGSKSAGRVQSVALRILCDRENEIGLFTPEEYWIVSVNMTDGEGLVIPTQLSHINGEKLERMSIRGAEEAEKIVEEIRELPFLVEEIKKKELKQKPSPPFITSTMQQTASTVLGFSVKKTMSLAQKLYEGIEIGGAIEGLITYMRTDATHLSVESVDAIREFIQKKFGQEYLPESPVLFKKKVKNAQEAHEAIRPTSIFRTPEEIESYLTPDQYKLYRLIWERALACQMSDAITSSQNIVFISQDEKFKTSASASLLIFDGFNAAFSHGKNKNKNQGVIDFIKKHKEGAQVKVGDVLPTQNFTEPPHRYSEAGLVKHLEELGIGRPSTYATVVSVLQERGYASIVNKSFIPENRGRLVSEFLVHFFSKYVEYHFTAEMEDRLDKVADGTIFWLDVIQDFWDSFHSNVEEVEKVPITEVLAFVNGALAKQKLVSAEVKVGDKCPKCEKGYMHLSVSRYGVFLGCTNYPVCRFIVNSYSTDDDTEYPKQIAQDISLHKGPYGIYLKYKGKNSSIPKDVDPVSIDEEFAHKIASLPKILGKHPADGKEIKMGLGPYGLYLFWNAKYYNLQFSQMDEMTLDKAVQFIQSYVIHDKSLLRVLGSYEGEEIQIRDGRYGPYIKCSKMNVPIPKAESPESLSIETAILLIEKKKNTSKSAKKVATKRKVSTKEKK
(1242) DNA topoisomerase 1 [Magnetospirillum magneticum AMB-1]
1
MRMKVVVVESPAKAKTINKYLGSDFHVLASYGHIRDLPPKDGSVRPDEGFAMDWETDPKSERQIKEIVAAVKGADKLFLATDPDREGEAISWHVRQVLEARKALKGVEVKRVVFNEITKSAVLDAMRNPREIHQELVDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICERESEIESFKPREYWTIAADFLTPKGALLSAGLTHLGGKKLDKFDLSSEALARDAESKAASARYAVAAVERKRTRRNPYPPFTTSTLQQEASRKLYFAAARTMQLAQRLYEGVDIGGETVGLITYMRTDGVQMAAEAIAGARAVIAQDFGKVYVPEAPRVYKTKAKNAQEAHEAIRPTDLARRPEDVARYLDKDQLRLYELIWKRTLASQMAAAELDQVGVDIAGDQHGIVFRATGSVVVFDGFLKVYREDKDDSDDEDAEKLLPDVTEKDAMDRKAMRTEQHFTQPPPRFSEASLVKRMEELGIGRPSTYASILSVLQERNYVRLDQRRFIPEDRGRLVTAFLESFFGRYVEYNFTADLENQLDDVSGGRDDWRKVLDRFWRDFSGAVDETKDLRVAQVLDALDELLGPHFFPDNGTGHDPRSCPTCNAGRLSLKLGKFGAFIGCSAYPECRFTRPLTTGGEGEEEVREGPKELGNDPESGLPVTLRKGPYGHYVQLGDETTLKAEPAPVPEKGKKAPKTAKAVKAPKPKRVSLYKGLEPAGVTLDIACRLLALPRLVGTHPETGKSISAGVGRFGPYVVHDGVYKSLAKDDDVLVIGMNRAMELLSQAKGRGGSGPLKTLGEHEGKPVTLHEGRYGPYVSRDGVHATLPKDSSIETVTLEAALALIAAKAAKGPAKPVRGRKAAAPKAEAAPKPAAAKKAPAKKKAPTKKKVAAKG
(734) DNA topoisomerase 1 [Acidiphilium cryptum JF-5]
1
MNAIVVVESPAKAKTINKYLGDGFTVLASFGHVRDLPPKDGSVRPDEDFAMSWEEDARGDRQVAAIAKALKGADTLYLATDPDREGEAISWHVRAMLEARNVLKGKQVRRITFNEITKSAVQAALRAPRDLDTPLIEAYLARRALDYLVGFTLSPVLWRKLPGSKSAGRVQSVALRLICEREAEIELFRPREYWTIEAEFRTPAGAPFRARLTHLDGRKLDQFDLADKAAADAAKAAVERGAFSVVSIEKKRVRRNPPPPFTTSTLQQDASRKLHMTAQAIMRTAQQLYEGVEIGGETVGLITYMRTDGVQMAREAITAARQQVKDAFGANYLPAAPREYQSKAKNAQEAHEAIRPTDFTLTPERAARHLSPEQARLYELIYKRALASQMQSAELDQTTVELADAAGTTLRATGSILAFDGFLKLYREGMDEDPEDETARLLPPMAKSDPLASGPVTAEQHFTQPPPRYSEATLVKRMEELGIGRPSTYASILTVLRERNYVRMENRRFIPEDRGRLVTAFLVSFFGRYVETGFTADLEEKLDEVSDGRLDWRSVMRDFWADFSGAVEQIKDLKISDVIDALDEELGPHFFPAREDGSDPRVCQACGTGRLGLRLGRFGAFIGCSNYPECQYTRRLAVEGGEDEGDQLRDGMKLLGENAEGIPVTLRRGPYGLYVQLGEPDPEDKKAKPRRAALPRGMSGETITLEQAIGLLSLPRVIGVHPETKQEIQAGIGRFGPYVKMGPIFASLDKDDDVLAVGLNRAVMVLAKKQEGIRDLGPHPKDGESVTARKGRFGPYVQHGKTVATLPRGSELGAVTLDEAVALLAEKGKTLAPRGRKGAKPAAKPKDAAAPKAARPAKAKAAAKPKAAAAKPEAAAAKAKPAARKTARSGG
(1357) DNA topoisomerase 1 [Rhizobium etli CFN 42]
1
MNVVVVESPAKAKTINKYLGSGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDGASAKRMKDIAEAVKSSDGLFLATDPDREGEAISWHVLDMLNKKRVLNGKSVKRVVFNAITKKAVLDAMADPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNISALLKTPRGDEFEARLVSAHGKRLPPRAIGNGEDAGRLKALLEGASYIVDTVEAKPIKRNPGPPFTTSTLQQAASSNLGFSASRTMQIAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARRAILDQFGERYLPEKARFYSTKAKNAQEAHEAIRPTDFNRSPDRVRKFLDADQIRLYELIWKRGIASQMASAEIERTTAEITAENKGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDEDGRLPEINARETLAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLIPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKQVLRDFWKDFFAQIEDTKELRVTNVLDSLNEALAPLVFPKREDGGDPRICQVCGTGNLSLKLGRYGAFVGCSNYPECNYTRQLSSENGGEAEGVALNEPKSLGTDPTTGEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGRHPETGKMISSGIGRYGPFLLHDGSYANLETVEDVFSVGLNRAVTLIAEKASKAPGRGARGTPAALKTLGDHPDGGAITVRDGKYGPYVNWGKVNATLPKGKDPQAITIEEALALITEKAGKAPAGKTARGKAKPKAAAAEAKTTKTAAKPKAAKAKAPAKLKKS
(1821) DNA topoisomerase 1 [Candidatus Puniceispirillum marinum IMCC1322]
1
MKVVIVESPAKAKTINRYLGDGYKVLASYGHVCDLPSKDGSVSPENDFEMKWQISSGSEKHLKEITSALKNADKLILATDPDREGEAISWHVLEQLKAKKLVNDMPVERVVFNEVTKSAILTAMDNPRALDEELIDAYRARRALDYLVGFSISPVLWRKLPGSKSAGRVQSVALRLICEREAEIEAFITDEYWSVDTRMAKADGREFTARLTHIDGEKLGKLDIPNEAAAKAAEAKINAADLSVKTIETKRVKRNPSPPFTTSTLQQEASRKLGFSASRTMQIAQRLYEGINIGSDTTGLITYMRTDGVQLGKESIAALRDDIGSRFGNRYLPDSPRIYKTKAANAQEAHEAIRPTDITRDPEAMRSFLDHDQFRLYELIWKRTISSQMQSAELDQTGVDITDPAGTVTLRANGQVMVFDGYLSVYMESQDDKDEKDETRSNLLPEMKEGENLDTQNVSPEQHFTQPPPRFTDASLVKRMEELGIGRPSTYASIIQVLQNRDYVVKDRNRFIPEDRGRLVSTFLGNFFDRYVEYDFTAQLESQLDEVSAGRLDWKALLANFWRDFKSAIDGTKDLTITNVLDVLDEELGPHFFKADENGALMRSCPNCDDGRLGLKLGKFGAFVGCSNYPDCKFTRKLTDSDGTEDDAPVGDKNLGIDPATELPVFLRKGPYGPYVQIGDPETKKPKRASLPKGESAAAIDLDRALSLLALPREVGAHPETGDMIQAGLGRFGPYLKYQGGFTSLPADDDLLTVGINRAVDLLAESAKKKGRVLGAHPAKGDVYVKAGRYGAYVEHNKLRATLPKDVDIADVTLEQAIELLAEKAAKTPAKKPAKKAAAKKKAAPKKKAATKKKATAKKSAKKDS
(487) DNA topoisomerase 1 [Gluconacetobacter medellinensis NBRC 3288]
1
MTDVVVVESPAKAKTINKYLGDNYTVLASFGHVRDLPPKDGSVLPDEGFAMKWEADERGSRQIAAIAKALRGAKHLYLATDPDREGEAISWHVRSMLEEKNLLKGIDVQRVTFNEITKSAIKTAMAHPRELDFPLIEAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICEREAEIEVFRPREYWSITARMTTPAGAAFSARLTHLDGHKLDQFDLGDEARAMAAKAAVEAGDYSVDKVERRKVRRNPPPPFTTSTMQQEASRKLGMGAQVAMRTAQQLYEGIDIGGETVGLITYMRTDGVQMAGEAIGAIRGHIGHSFGPEYVPEKARIYSTKAKNAQEAHEAIRPTDVRRTPADMARYLSPEQKKLYDLVWKRSVASQMQSAELDQVAVDITDRQQRVTLRATGSIIAFDGFLRLYSEGRDDSPAKSDDDQDRMLPAMSEHDAIGRGEVAADQHFTQPPPRYSEASLVKKMEEIGIGRPSTYASILTVLRDRNYVQLENRRFVPEDRGRLVTAFLTSFFERYVDTQFTAGLEEQLDDISGGRANWRDVMSAFWSDFSHAVDQTKDLKISDVITALDADLAPYFFPDREDGQDPRVCTACGTGRLGLKLGRYGAFIGCSNYPTCQFTRKLVIDPSKEGEDAATLKDGMRVLGTAPTGEEVTVRRGPWGLYVQQGEPDPEDKKAKPRRATIPRGLDGDKITLVQAVGLLSLPRIVGIHPELGEPIEAGLGRFGPYVKMGAIYGSLDKDDDVLTVGLNRAVDALAKKLASIRTIGPHPKDGEPVMVRKGRFGPYVQHGTIVATVPRGQDMADVTMEEALTLLNEKGKPLKAKGKKATTTRKPAARKTKAKAAEGTEDAGAAPKKKAAPRKAASKAKTATKTTTRKKATPAKAESESD
(1663) DNA topoisomerase 1 [Brucella canis HSK A52141]
1
MGREFRLLYMNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYTIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRITNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRNIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
Family distribution
Taxonomy tree
Alphaproteobacteria