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Taxon : Epsilonproteobacteria
Informations
Name
Epsilonproteobacteria
Rank
class
# topoisomerases
32
Lineage and sub-taxa
Lineage
Bacteria
>
Proteobacteria
>
delta/epsilon subdivisions
>
Epsilonproteobacteria
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(1113) DNA topoisomerase 1 [Wolinella succinogenes DSM 1740]
1
MKNLIIVESPTKAKTIKNFLGKEYEVIASKGHIRDLPKHNFGIKIEGQSFLPDYKIEKGHEAVVKEIKALAQKAKTIYIATDEDREGEAIGYHISHAIDKDPTTLPRIVFHEITQNAIKHALETPRSINMDMVNAQQARRLLDRIVGYRLSPLISSKIQKGLSAGRVQSSALKLIVDREREIRSFVPVTYFTIEALFEKGIEAELIEFEGEKLEKLSIGESKKANEMVKVLQKESWSITGIEHKRRKTSTPPPFMTSTLQQSASSVLGFSPSKTMMAAQKLYEGVMTHQGVMGVITYMRTDSLNIAKEAQEAARSRIKEVYGERYLPKEPKVYTTKSKSAQEAHEAIRPTLIDFTPQLAAQYLKGDELKLYSLIYNRFLASQMNDAEFELQTILLGSSKGVFKVSGRKLIFDGFYRVMGSEDKDKLLPELQKGEALKLEECKANRHETEPPARFSEASIIKTLEALGIGRPSTYAPTISLLAGRDYIRIEKKQIIPEEVAFKVIEVLEAHFTEIVDSHFTATLEEELDEIAESKKDWQKVLWDFYEKFDAKIALGKKNIESQKVAIPTGEMCPKCGAELVRRMSRYGEFVACSGYPKCKYIKPQESSPEQEGEESEEVCEKCGKPMVKKRGRNGEFLACSGYPDCKNTKSLKKSSTPKKVLEVKCPKCGGEIIERSSRRGNFFGCANYPKCDFISSHEPINEKCQKCGGMMAKRTYRKKEVHECIACKDRIEVEERNEEEK
(1863) DNA topoisomerase 1 [Campylobacter lari RM2100]
1
MKNLIIVESPAKAKTIGNFLGKDYEVIASKGHIRDLPKSSFGIKIEDENFKPEYRISSDHSTLVKELKEKAKNAKQIYLATDEDREGEAIAYHIAKAINKDENSLPRIVFHEITKSAIENALNNPRHLDINSVNAQQARRLLDRIVGYKLSPLLNQKIQKGLSAGRVQSAALKIIVDREREIKAFTPLKYFSIDVIFKKDLEAELVEFQGQKIEKFTITNEDRAKLIFENCKNAKFKINNIESKDRKITPPPPFMTSTLQQSASNRLGFNPKKTMMIAQKLYEGVKTHQGIMGVITYMRTDSLNIAKEALEQVRKLIKDEFGKEYLPAKANIYTTKAKGAQEAHEAIRPTNLSFTPKLASEFLEKDEARLYTLIYNRFLASQMNPAISQTQNVYAKSNEASFKISGRKILFDGHYKVYGDMDKDKILPNLKLEDTLNIQNIEFNSHFTEPPSRYSEAGLVKKLENLGIGRPSTYAPTISLLSARDYVRIDKKQLIPNEIAFNVIEVLEQNFSDIVDSDFTFKMEESLDEIAEGKLDWQELLREFYFPFMRKIDEGKKNIKSQKTITKIDETCPDCGGELAIRKGRYGEFIACLNFPKCKYSRNLKQENKNEEKTQIKQVNSIGLTCPECKKGEIVERFSKRGKFYGCSAYPKCNFISKYKPSEEKCEECGENLIIKELKKGTFLECLKCKIKKEI
(409) DNA topoisomerase 1 [Sulfurovum sp. NBC37-1]
1
MKNLIIVESPAKARTITSFLGKDYKVIASKGHIRDLPKSTFGITIDDETGDLIPKYSIPRDANPTVKELKKLAKEAETIYIATDEDREGEAIGYHIAKAIGKEPTELPRIVFHEITKSAIQHALENPRKVDMDSVDAQQTRRLLDRIVGYKLSPLLASKIQKGLSAGRVQSSTLKIVVDREREIKAFKPEEYWTIDALFEKNIDASIYDYNGLKIDKLTIKTDADANEIVESAKGESFVVSSIEKTKRKTKTPPPFMTSTLQQAASTQLGFSPKKTMMVAQKLYEGVKTDKGTMGIITYMRTDSLNLAKEAVEAARTHIKETYGDKYLPAKAKHYTSKSKGAQEAHEAIRPTRVDFDGTKAANFLNADELKLYRLIYNRFLACQMTEAELESQTILFKGDKCTFKASGRKLLFDGFYRVTGYNEKDKLLPELKKEQPVSLDDIKAEQHFTEPPARYNEASLIKKLESLGIGRPSTYAPTITILQTRKYIEIEKKRIHPTEIAFTVIEMLEKHFPEIVDSGFTANMEETLDKVAEGETDWQTILKEFYTPFLQKIEEGKKNIKSLKVAIPTGENCPKCGSELLLRKGRYGEFIACSNFPKCKYTKNTDGTEVEQPEETDEKCEKCGSPMVIKNSKRGKFLACSAYPKCKNAKSLTPPKELSVPCPECGGKLQEREGRRGKFFGCENYPKCKFIANFEPVDKKCPECGYTMGKKTLRGKEIFECFKCKHKEEAK
(359) DNA topoisomerase 1 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
1
MKKNLIIVESPAKAKTIGNFLGKDYEVIASKGHIRDLPKSSFGIKIEDDEFIPEYRITSDHSALVKELKSKAKDAKEVYLATDEDREGEAIAYHIAKAIGKDENTLPRIVFHEITKSAIENALKNPRKLNMHSVNAQQTRRLLDRIVGYKLSPLLGQKIQRGLSAGRVQSAALKIIVDREKEIRAFVPLEYFSIDMIFQKDLDAELVEFDKAKIEKLTITNKDRAKLILEACKNEVYSISDIESKERKIAPPPPFMTSTLQQSASNRLGFNPKKTMMIAQKLYEGVNTHEGVMGVITYMRTDSLNLAKEAVENARKFIQANFGKDYLPSKANVYTTKTKGAQEAHEAIRPTNLSFTPEIAAKFLDKDELKLYTLIYNRFLACQMSPAISQTQNVFVKNDRVVFKISGRKILFDGYYKVYGDMDKDKILPNFKIGQNLKVQNLEMNSHFTEPPSRYSEAGLVKKLESLGIGRPSTYAPTISILTSRDYVTIDKKQLIPSDVAFNVTEVLEKNFSDIVDSKFTSNLENTLDEIAEDKADWQETLKEFYYPFMRKIEEGKTKIASQKTVTKLGESCPDCGGELAIRKGRFGEFVACLNFPKCKYSRNLKSESKNESENTAAKAKANGTGITCPSCQKGEIVERFSKRGKFYGCSAYPKCNFISKYKPSEEKCEECGETLVIKELKKGTFLECLKCKIKKEMKD
(123) DNA topoisomerase 1 [Campylobacter concisus 13826]
1
MKSLIIVESPAKAKTIKNFLDKSYNVIASKGHIRDLPKTSFGIKIEDDKFTPEYRISSDHSAIVKEIKELAKGADEIYLATDEDREGEAIAFHIANAIGKEPTSLPRIVFHEITKSAIQNALKSPRHVDMNSVNAQQTRRLLDRIVGYKLSPLLNLKIQKGLSAGRVQSAALKIIVDREREIQAFKPVEYYTIDTVFKKDLDAELVKFENQKIEKLTIQNPDRAKYIIENLQNEKFSVREIESKDRKIQPSPPFMTSTLQQSASNRLGFSPKKTMMIAQSLYEGVQTNEGFMGAITYMRTDSLNLAKEAVAAAREHILQNYGKEYLPAKAISYTTSSKGAQEAHEAIRPTNLNFTPQIAAKFLEKDALKLYTLIYNRFLACQMSACVSQTQNVYVASEKGEFKISGRKVLFDGFYKVYGELDKDKILPNLKKGDEMSLQSIKSTQNFTEPPARYSEAGLVKKLESLGIGRPSTYAPTISLLTSRDYVRIEKKQLIPNEIAFSMIGVLEEHFSNIVDSEFTSHLEEKLDEIALDKADWQKVLSDFYYPFMEKISAGKTGIKSLKTATPIGEKCPECGSELVLRKGRYGEFIACSNFPKCKYSRNVAKDNEKSAETGSTTAAKPKRELKKLDVPCPKCGGEIVERFSRRGKFYGCANYPKCDFISNYEPVAQKCDECGGDMIKKELKKGTFIECTKCKKKTLVSEN
(596) Reverse gyrase [Nautilia profundicola AmH]
6
MLHIIYKNECPRCGGDISSVNLNKGMFCDECMKSKKKEWNLENCENLLNYEKYCIADKKVNEFNEFFKFKCGNELNSIQKMWAKRFFLDNSFALLASTGIGKTTFGLLLSAFVKNSYILFPTKLLVAQAAEKYKKWGIEFVAYMGKKSEKELIEKGEYDILITTTQFLYKNRSLIKRNFELIFVDDVDSILKSGKKIADILTLLGIDKNSIEKTYELIKNQKYSEIKSVSKKGNLIVSSATANPKSKKILLFKYLLGFEVSRPNFNLRNIEDLYDENYSWDHSVKWINELGRGGLLFLPGNETKDTLYEYIDFLNTKNIKAYSYEDFEKHLEEFKEGKCFFVGFASYKNPLARGIDLPEYIKYTLFVGVPKIEFNLKDENFRAFYFIMLSLLPYLVKNNLSQKEVSEIQNDLNYLKKYIYLSKINVNTQQKIADILIRFKNTVKKYEDIIKTAENISFDGEKFIIADVTGYIQASGRSSRFYKGHLTKGLSLLLVDNKKAFYSLKKKLKWFGEIEFKNVEDVDIKKVLTEIEKSRTENVKTEFKTSFVIVESPTKAKTISSFFGNPSKRIINNVAVYEVLSQDRVLIIAASIGHDFDLVKDEGVWGVKDLIPIFHVLENKDKILQTLNINANEVEEVYAATDPDREGEKIAFDLTMINKPYNMNIKRIEFHEITKQAFEEALSIPREIDLNLVKSQLFRRITDRWVGFKISLYLQRLLNNTHLSAGRVQTPVLKWICERTGLLKEKIYVVIIRFNNVSIDFEFDTKQEANEFFNSLKESVYIKKLSSNTEVMFEKPFNTPDLLKEASNKLRFSPQKTMQLAQELFEKGFITYHRTDSYRISDTGKAIAKTYILENFSKDYLKFRNFESKGAHEAIRATTSMDADELRSYMLERNILLSEEHLRLYDLIFRKFIASQMKEAKVLKEKFLILLKEKSFITEIVENGYNLIYPINIYIISEGENKIVKELRQKPKAAPYTYAEVIEEMRSKGIGRPSTYAIIIEKLLKRKYITDKNGYLFATKLGFRIIKEVYKSDFKDFVSEEFTAELENIMDKIEEGKTEYEKELKKLFSLLF
(705) DNA topoisomerase 1 [Nautilia profundicola AmH]
1
MAKNLIIVESPAKARTIKNFLGKEYEVVASKGHIRDLPKTSFGIKIEEDKFIPQYRVTADHQPIAKELKEKAKKAETIYIATDEDREGEAIGYHIAHVIGKKPEELPRIVFHEITKTAIKKALENPRTIDLNRVNAQQARRLLDRIVGYKLSPLLNKKIQKGLSAGRVQSAALKLVVDREREIKAFKPQEYWSIEGIFKKIEGSLIKYNGKKLDKFDIKSKDEAQKIVEELKPLEYTVREIETKTTTVKSPAPFMTSTLQQVASSELGFSPRKTMQIAQKLYEGVKTPVGETGIITYMRTDSLNIAKEAQQAALEFIKQNIGEEYAQAKTYATKNQNAQEAHEAIRPVDVRLTPDDLKNYLKPDELKLYALIFNRFLASQMKDAKFETQNIYIANDKGEFKISGRKLIFDGFYKVYGKPSANTLLPEFEKGEKLKPEDVKATQHFTKPPERYTEASLIKKLESLGIGRPSTYAPTITLLQNRNYVEVKDKKLHPTEIAFSVIETLEKHFPDIVDANFTANMEEMLDEVAEAKKDWQEVLKDFYNPFMELVNKGYKEIPSQKIAKPIDETCPLCGSPLVIRKGRFGEFIACSSYPKCKYTRPLEESKEEKKTDVKCDKCGADMVVKKGKSGEFLACSNYPKCKNTKPLNAPEVLDDVKCPECGGDIVKRKSRRGEFYGCANYPKCNFISKYRPVNKKCPECGYLMAERTYRKKDVYECIKCKHREEAKK
(997) DNA topoisomerase 1 [Sulfuricurvum kujiense DSM 16994]
1
MKLIIVESPAKAKTIKNFLSKDYEVIASKGHIRDLPKNRFGIKIDDEKIIAEYRISEDSTATVKQIQELAKKSDTIYIATDEDREGEAIGWHIAHAIDKDPSSLPRIVFHEITKNAIIHALETPRTIDMDRVNAQQARRLLDRIVGYKLSPLLANKIQKGLSAGRVQSSTLKIVVDREREIRAFIPEEYWTIDTLFKKDIEAALVNFENEKIDKLTIKTGDEAARIVETLKGESFKVGEIETKERKSSTPPPFMTSTLQQTASSQLGFSPKKTMMVAQALYEGVKTPEGTSGVITYMRTDSLNLATEAVEAAREVILTRYGKEYLPKEAKVYTKKSKGAQEAHEAIRPTMLGFTPEVAATYLKPDEIKLYRLIYNRFLACQMNDARFEQQSITFESAKAQFRATGRKLLFDGFYRVTGSDDKDKLLPSLTTGDSIEIQTVTPEQHFTEPPARYSEASLIKKLESEGIGRPSTYAPTISTLQARNYIEIEKRAIMPTEIAFTVTEMLENHFNEIVDASFTATMEETLDEISESGKSWHKILLDFYYPFIEKIDAGKSNIVSLKMAKPLGRNCPQCGSELLLRSGRFGEFIACSGFPKCKYTEQTEENQKENPATPDEVSEEVCDKCGSAMVVKNGRNGKFLACSGYPKCKNTKTLNQETKFSQVPCPECGGKLLWRQSRRGAFWGCEHYPKCKFISKFEPSDKKCEVPGCGGALAPRTYRNKEVYECVKCKDRTPREEAGE
(572) DNA topoisomerase 1 [Arcobacter sp. L]
1
MASMGHVRDLPKSSLGFDPSDNFKPKYMVTADKKKVISDLKKHISKDTTIYLAADEDREGEAIAWHLIPALKIEKNPIKRIVFHEITKDAILKALENPRDVDQHLVDAQQARRILDRAVGYELSPLLWKKVRYGLSAGRVQSVAVRIIVDRENEIRAFVPEEYWKVKADFINPELKAELAKISAKTAKVDNEEQALNIESSLNQGIYKLASIEEKESIRNPAAPFTTSTLQQEASRKLGLSVKQTMVIAQQLYEGNVGNIPNHTGGLITYMRTDSLNLSTVATSAAKAVIEEEYGKEYSLSKPRVYKSTAKGAQEAHEAIRPVNLALKPSMIKEFVEPAQYKLYSLIWKRTLATQMAQAKIANTTYKIEAGRDKEFEFQSKGQRIIFAGFMKAYTEGSDNPEAALDSTEKILPNIKVGTVLELEKLESEQNFTKPPARYTEASLVKKLESEGIGRPSTYAPTISTIQAREYVTKTEDKKLIPTQTGEIVNSFLVDHFSDIVDLGFTAKIEEEFDEIALGKIAWEQVMKDFYGNFKKTIDEKEESVHKEDYLQSREIGIDPKSGKPVSARVGRFGPFIQIGTKDDEEKPKFVAIPDNLNMDTITLDEALFLFTLPRVVGLDNSGDEIKANIGRFGPYLQVKTKFYSLKTDDPYTVDLNRALEIIKETDEAKEKSTIKTFDKEKIQILIGQYGPYIKQGRKNFKIPKSVEAKDLTLEQCLEIIAKDSKTKTSSTKKASTEKKASTEKKETKKKTTTAKKTTKKSADK
(1699) DNA topoisomerase 1 [Sulfurimonas autotrophica DSM 16294]
1
MNLIIVESPAKAKTIKNFLGKDYDVIASKGHIRDLPKSRFGITLDEETHELVPKYSVAKENAPTVKEIKEKAKKADTIYIATDEDREGEAIGWHIAHAIKKDPLELPRIVFHEITKTAIKHALESARKIDMDMVNAQQARRLLDRIVGYKLSPLLASKIQKGLSGGRVQSSTLKLVVDREREIKAFVPQEYWSIDTVFKTNIDANLIKHKDKKLSKLSIENKEQAETITQSVKNDNFTIAKIETKQRKSSTPPPFMTSTLQQTASSKLGFTPKKTMMIAQTLYEGVKTPDGTSGVITYMRTDSLNLAQEAVGAVRGIIENRYGKKYLPKEPKIYTKKAKGAQEAHEAIRPTMLQFTPEVAQSFLKADEIKLYRLIYERFMACQMEDAIFEQQSIIFKGNENEFRASGRKLIFDGFYAVTGTEDKDKLLPTLKEGEKAEIQSVKPEQHFTEPPSRYSEASLIKKLEAEGVGRPSTYAPTIATLSNRTYVTIEKKQIIPTEIAFTVTEILEKNFPNIVDINFTAEMEEELDEIAEGKVDWQKLLLEFYEKFMKQIEEGKENIVSLKLAKPLGRTCPKCGEHELLLRSGRFGNFIACSGFPKCKYTEQCDEEGNAVEKKETTADEKCDKCGADMIVKNGRNGEFLACSNYPECKNTKSINVEEKVSETPCPDCGGKISLKNSRRGPFWGCENYPDCKFISKFEPTTIKCKEEGCSGVLAPRTYRNKEVYECVKCKARTPKEEIDTKK
(375) DNA topoisomerase 1 [Arcobacter butzleri RM4018]
1
MASMGHVRDLPKSSLGFDPNDNFKPKYQISTDKKKVITDLKKHISKDTTIYLAADEDREGEAIAWHLIPALKIEKNPIKRIVFHEITKDAILKALENPRDVDQNLVDAQQARRILDRAVGYELSPLLWKKVRYGLSAGRVQSVAVRIIVDRENEIRAFVPEEYWKIKADFINPELKAELAKENGKTLKISNEKQALEIEASLKQGSYKLVDIEEKESTRNPAAPFTTSTLQQEASRKLGFSVKQTMIIAQQLYEGNVGNIPNHTGGLITYMRTDSLNLSTVATTAAKAVIEEEYGKEYALNKPRVYTTKSKGAQEAHEAIRPVNLALRPSQIKEFVEPAQYRLYSLIWKRTLATQMAQAKIANTTYKIEAGKNKEFEFQVKGQRIIFAGFMKAYTEGSDNPEAALDSSEKILPNIKEGTILELEKLESEQNFTKPPARYTEASLVKKLESEGIGRPSTYAPTISTIQAREYVSKTEDNKLIPTQTGEIVNSFLVDHFSNIVDLGFTAKIEEEFDEIAEGKIAWEEVMKNFYGGFKKTIDEKESSVSKEDYLQVNELGIDPKSGKPVSARVGRFGPFVQIGTKDDEEKPKFVAIPDNLNMDTITLEEALFLFNLPRVVGNTENGDEIKANIGRFGPYLQVKTKFYSLKTDDPYTIDLNRALEIIKDIDEAKEKSTIKTFDKEKIQILVGQYGPYIKQGRKNFKIPKGKNAEDLTLEECLEIIEKDSKGSTKRTTTKKSATEKKTTAKKTTKKSTDKK
(1827) DNA topoisomerase 1 [Helicobacter felis ATCC 49179]
1
MGKNTKLIIVESPTKAKTIAHFLDNSYEVIASKGHVRDLSKYAMGIKVQDNKFIPKYAIDKDHEEIVAQILQKAKNAQEIYIATDEDREGEAIGYHIAYLIDQAGNRSKDPLIEMRALEEQSQTKNPHPIFAFPRIVFHEITKTAILHALKHPKTLDVHKINAQLARRLLDRIVGFSLSSLLASKISKGMSAGRVQSAALKLVVDREREIKVFKPIIYYEITGTIAQASVSLQSYRHEKIKKQGLRDSKEALEMVANLSAQTYQVQEISTKEKNTPSPPPFMTSTLQQSASNQLGYSPSKTMSIAQKLYEGVMTSEGVSGVITYMRTDSLNIAKEAIESARVFIEQTYGAPYVPKKPKVYTSKNKSAQEAHEAIRPTNLAFTPAIAKDYLKPEEHKVYTLIYQRFLASQMSDARLESQSVSFACESLGAVFKASGHKLLFEGFYKVLGNGDKDTLLPSFTLHQEVRLEKLEAKECSTQPPARYSEASLIKTLESLGIGRPSTYAPTIALLLSRDYVSLQQKQLTPTPNAFSVIEILEKHFSEIVNATFSAGLEDKLDAIASHELNWQDMLLKFYTPFMAQIEEGKIQIASQKVSAPTGESCPKCGAPLVQRTGRYGVFVACSAYPKCKFIKSEVVQTEDLGVCEKCGAPMVSKRGRFGTFVACSAYPTCKNIRNEESKNTPALAKCPQCGGDVRAKRGKRGMFYGCDNYPSCKFISNYKPAPKPCPECGGLCVMKIYKTKPSVQECLQCHIQVEIEGEQV
(880) DNA topoisomerase 1 [Helicobacter pylori F32]
1
MKHLIIVESPAKAKTIKNFLDKNYEVIASKGHVRDLSKFALGIKIDETGFTPNYVVDKDHKELVKQIIELSKKASTTYIATDEDREGEAIGYHVACLIGGKLESYPRIVFHEITQNAILNALKTPRKIDMSKVNAQQARRFLDRIVGFKLSSLIASKITKGLSAGRVQSAALKLVIDKEREIKAFKPLTYFTLDAYFESHLEAQLISYKGNKLKAQELIDEKKAQEIKNELEKESYTISGIIKKSKKSPTPPPFMTSTLQQSASSLLGFSPTKTMSIAQKLYEGVATPQGVMGVITYMRTDSLNIAKEALEEARNKILKDYGKDYLPPKAKVYSSKNKNAQEAHEAIRPTSIVLEPNALKDYLKPEELKLYTLIYKRFLASQMQDALFESQSVVVACEKGEFKASGRKLLFDGYYKILGNDDKDKLLPNLKENDPIKLEKLESNAHVTEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEKKQISALESAFKVMEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHEKTGQSCPKCGGELVKKNSRYGEFIACNNYPKCKYVKQTENANDGAKQELCEKCGGEMVQKFSKNGAFLACNNYPECKNTKSLKNTPNANEIIEGVKCPECGGDIALKKSKKGSFYGCNNYPKCRFLSNHKPINKRCEKCHYLMSERIYRKKKAHECIQCKERVFLEEDDG
(764) Topoisomerase I [Helicobacter pylori F32]
3
MKDSVIIIESPNKVAKVKEITGAKVFATIGHFMQLKSYDENNNFKPTFEYDSQKKKRIFEIIEACKNKKVYIATDPDREGYAIGYHFYEKIKKIASSIYRAEFFEITPSGINKGLQNALLFENTNKQMYQSALARRVADMLLGFTLSPYLGKALGQMKGSSAGRVQTPCLKLIVDRDREIEKFKALPENEKVSYQIQAKINDNANREVIIKHCDEKGEEIKFNDKEEALKLFESLKDNKACLLKDLKISVVETKPKKPFITSTLLERASSELGLGIAEVQSLAQSLFEAGLITYIRTDAESLSVEFLNEAESFYLPIYKEVYQKREYKAGKQSQAEAHEAIRITHPHKYEDLESIVYNAGITNQDALKLYRLIFERTIESQGKNAIYDKQDLLFKIKNEYFKCSAKSLKSTGFLAMFSKKELENDDESNDDKEDKEKEQNAQFNLKIDDMLSLNDLVLATIKRNAPSPYKEASFVKLLENKGIGRPSTYASYLSTLLKREYISISQDKKHTITPTHKGKRVIEVFENAYQFIIDLTYTKQMEEVLDEIVENKSSYLDFLQNLATKCPKIEKLERNDDEIKPSSEGQITYIENILRDLQLDLSEEFKNYKEDNRIAKAFLDRYIKEHEFFEKNNKKASSSNNNEIRPATPKQINFAEILAKKHNVKLPKDYKSNIKVCGDFINEYHKK
(1497) DNA topoisomerase 1 [Helicobacter hepaticus ATCC 51449]
1
MKDLIIVESPAKARTIKNFLGSKYEVIASKGHIRDLPKYTFGIDIKDKTFHPQYTISKDHMEIVEKIKVASKKAKVTYIATDEDREGEAIGFHITQALNLPYEKIPRIVFHEITKNAITHSLQNPRQIDMAKVNAQQARRLLDRIVGFKLSELISSKIQRGLSAGRVQSSALKIIVDREREIRAFKPTIYFLINAVFNMKPKSKQKNQDNGQNNIEAELITYDKKLEKLSLQNFEAVEAMLEHIQKQQFFIKEIITKSKKISTPPPFMTSTLQQSASSLLGFSPSRTMSIAQRLYEGVETNFGSMGVITYMRTDSLNIAKEAQKAAREMIIKTYGKEYVPAKTKNYATKSKAAQEAHEAIRPTNLDFTPEIAKSYLKPEEHKLYALIYYRFLASQSQDALFEIQNIIFTPHNQTHLIEFKASGRKLVYDGFYKIMGNDDKDKLLPECKEGEDVLLNNIESVQKSTEAPSRYSEASIIKSMESLGIGRPSTYAPTIALLVAREYVNIEKKQLVPQESAFKVIEMLESYFDEIVDTHFTAGLEDKLDEIAQAKMNWESVLWEFYQPFMQKIESGKKVIVSQKVAIPTGEMCPKCGKELVQRKSKYGEFIACSGYPKCKYIKPTQQDSQSQSQEYGVCEKCGEPMIKKFGRNGEFIACSGYPKCKNTKSLTDKAQAHSVEGVVCPECEGEIVKRFSRRGAFYGCKNYPKCTFISKFEPIKEKCPQCGGISVEREYRKKQVRECLKCKHRIEI
(525) DNA topoisomerase 1 [Helicobacter canadensis MIT 98-5491]
1
MSLKDLIIVESPTKAKTIKNFVGSNYEVIASKGHIRDLPKHSFGIKIDNQEFIPEYKIDESHKNIVSELKKLAKDSKTIYIATDEDREGEAIGFHIATAIGKDPQKLPRIVFHEITKKAILDSLKNPRHIDMDKVNAQQARRLLDRIVGYRLSPLIASKIQRGLSAGRVQSSALKIIVDREKEILNFKPITYYSIDIAFKEQLESELLEFKGKKIQKLSLQDKAEALEMIQQLKQESFKVKEIENKKRKTATPPPFMTSTLQQSASSILGFSPSRTMQTAQKLYEGVMTHKGSMGVITYMRTDSLNIAKIAQDEAREFITKTYGKEYAPSKPKNYATKAKGAQEAHEAIRPTLVDFTPQIAAQYLKGDELKLYTLIYNRFLASQMSDAEFELQNIFIDSNSSLLKISGRKLIFDGFYRILGNEDKDKLLPHLKVGEVLKLEKCDLSEHQTEPPARFSEASLIKTLESLGIGRPSTYAPTISLLNSREYISIEKKQIKPQEIAFKVVELLEKHFLEIVDSKFTANLEEKLDEIAENKQDWQKLLWEFYEPFIQKVNEGKTSIQSQKIALPTGENCPLCGKELIKRSGRFGEFVGCSGYPKCKYIKKEVEENAQEESYGVCEKCGKPMVKKRSRSGEFLACSGYPECKNTKSLNNSAPSAKKAVEGVKCPKCSGEILERMSRRGKFYGCANYPKCDFISTYEPTNVHCPKCNSLMAKRTYRKKAVLECIACKERIEEIQTTIKE
(640) DNA topoisomerase 1 [Campylobacter fetus subsp. fetus 82-40]
1
MSKLIIVESPAKAKTIKNFLGSEYKVIASKGHIRDLPKSSFGIKIEDDKFTPEYRVSSDHSAIVKEIKDLAKNADTIYLATDEDREGEAIAYHIAAAIGKKPEMLPRIVFHEITKSAIQNALENPRSLNMDSVNAQQARRLLDRIVGYKLSPLLNSKIQRGLSAGRVQSSALKILVDREREIRNFKPIEYFSIDTKFKKDLEAELVEFEGSKIEKLTITNKDRAKFIVDKIKDESFSVANVESKERKTSPQPPFMTSTLQQSASNRLGFSPKKTMMLAQNLYEGVQTNNGFMGAITYMRTDSLNLAKEAISAARDLIKEQFGDKYLPKSANFYTTKNKGAQEAHEAIRPTNLSFTPTEAAKFLEKDLLKLYTLIYNRFLACQMSASVSETQNIFINSKSSIFKISGRKLTFDGFYRVYGDLDKDRILPNLNVGDKMELESLSSQSHFTEPPSRYSEAGLVKKLESLGIGRPSTYAPTISLLTSRDYVKVDKKQLIPNEIAFNITSMLEEHFNDIVDSDFTSKMEEKLDDIAENKADWQEVLSKFYHPFMQKIDDGKKNIKSQKVTEPIGEKCPECGGELVKRKGRFGEFIACLNFPKCKYSRNLKNEAKIEKKEPQKIGVACPQCGGDIVERFSKKGKFFGCANYPKCNFISKYQPTDQKCPQCGEMMVYKELKKGNFYECSACKFKKEGNNNE
(1703) DNA topoisomerase 1 [Nitratiruptor sp. SB155-2]
1
MGKNLIIVESPAKARTIKNFLGKEYEVIASKGHIRDLPKSSFGIKIEEDKFIPQYRVDKEHSQITKQLKELAKKADTVYIATDEDREGEAIGYHIAEAIGKKPQELPRIVFHEITKSAIQKALQNPRTIDMNRVNAQQTRRLLDRIVGYKLSPLLSSKIQRGLSAGRVQSAALKLVVDKEREIQAFKPQEYWSIDAIFNDTIEAALYEYMNKKIGKMDIKNEKEAQAIVDQVKNESFVVAKIEKKKRITKSPAPFMTSTLQQTASSKLGFSPKKTMMIAQKLYEGVQTPKGITGVITYMRTDSLNIAKEAQEAARDLIKKQFGEKYLPKKPKEYATKSKGAQEAHEAIRPTMLDFTPEVAKNYLSADELKLYTLIYNRFLASQMEDAVFETQTIYFKSPSATFKASGRKLIFDGFYKVLGNEDKDKLLPDLKEGEEAKLTKIEANQHFTEPPARYTEASLIKMLESLGIGRPSTYAPTIALLQARNYIELEKRAIKPTEIAFKVIEVLEKHFPEIVDSSFTAKMEEELDEIAEAKKDWQKVLKAFYDPFIELIEKGKKEIKSQKVAIPVGRNCPECGAELVKRKGRFGEFIACSAFPKCKYTEQIESEEKGPQESNEVCEKCGSPMVVKQGPRGSFLACSAYPKCKNTKPLAKNEPKKLDVKCPECGGEIVERFSRRGKFYGCSNYPKCTFVSKFEPVDKQCSECGYMMAKRTYRNKEVYECIKCKHREEVQ
(69) Reverse gyrase [Nitratiruptor sp. SB155-2]
6
MIDLVYKGLCPNCGGDICSDRLDKGLLCKRCMPKEGEPCEVLKEGEFVKVCEVEQRSVEFEAFFKEKNGFLLRQIQKSWAKRFFLGHSFALLAPTGVGKTTFGLSLASFLDQKSYLLFPTQLLVNQAVEKLRLLGIEPLFYDSGFSKSKKDEVKAKIASGDFEILVTTTAFFYKNFDSIPKAFGFVFIDDVDSILKSARNIDKVMLLLGFSQEDIDAAMQFIDHKIKGDLSYEEFEQWQAKIEAIRSHAKAQLIVSSATANPRSRRVGLFRELLGFEVSRPSITVRNVEDLYEKPEKLWERSVELVERLGRGGLLFLPGNETKERLQEFLAFLEQKGVKAQSYEDFDAKAFEEGEVEVLVGFASYRNPLARGIDMPATIRYALFVGVPKLEFTLDITKHTSLYFFLLALLPVIRNHPNFHQFMQYVNYLKRLVRVPTERLNEKAKARVQTIYHDILAILDEELIDAINKTPDVSLVKEDEYFKIITADVTGYIQASGRTSRLYVGGLSKGLSYLLVDSEKTFSSLQKKVRWFSEEIVFKSAKEADIDAILKIIDEDRKKIALALQGKFQEAKEFFTTSLVIVESPNKARTIANFYGKPMVRDLGGIRVYEVAKEGKILSITASKGHVVDLQKQEGVYGVLRQEHFIPLFEPIDENKRRIIEALRRIGVEVQDVYIATDPDVEGEKISYDLQLLTKPYNHTVQRAEFHEVTKRAFDEALSHPRDFDENLVKAQLVRRIADRWIGFSLSQMLQKKLQKSWLSAGRVQSAVLEWIVLREKEAKEKIFVVHVSFRGLEAEFVFDEKQKAKDFYERLEVVEVRFIQKETKELFRTPFTTDAMLYAASSELHFSPQKTMQLAQDLFESGFITYHRTDSTRISSVGIAIAKEYIQSRFGQDYFVPRSHSKAGGAHEAIRPTKAMDAQELEQFLQMQNSNLTQDHLKLYDLIFKNFIASQMKSAKIEEIAAQVEAFDQKTTIRFYDEIVEHGIDLILPVQLHQLQEGRYAVQKELLTRSKVPKYSYADVIRLMKERGIGRPSTYAITIQKLQERHYIVQRRGILYPTKLGQEVYEELRKNPEVYTFVNEHYTKELEALMDRVEKGEVSYEEVVESLYLQLKERIEF
(751) DNA topoisomerase 1 [Helicobacter acinonychis str. Sheeba]
1
MKHLIIVESPAKAKTIKNFLDKNYEVIASKGHVRDLSKFALGIKIDETGFTPNYVVDKDHKDLVKQIIELSKKASTTYIATDEDREGEAIGYHVACLIGGKLESYPRIIFHEITQNAILNALKTPRQIDMSKVNAQQARRFLDRIVGFKLSSLISSKVTKGLSAGRVQSAALKLVIDKEREIKAFKPLTYFTLDALFEPNLEAQLVSYKGNKIKAQELIDGKKAQEIKNELEKESYIISSIVKKSKKSPTPPPFMTSTLQQSASNLLGFSPTKTMSIAQKLYEGVATPQGVMGVITYMRTDSLNIAKEALEEARDKILKDYGKDYLPPKAKVYSSKNKNAQEAHEAIRPTSVILEPNALKDYLKPEELKLYTLIYKRFLASQMQDALFESQNVVVACEKGEFKASGRKLLFDGYYKILGNDDKDKLLPNLKENDPIKLEELESNTHVTEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEKKQIRALESAFKVIEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHEKTGESCPKCGGELVKKNSRYGEFIACNNYPKCKYVKQVENAHNEAKQELCEKCGGEMVQKFSRNGVFLACNNYPECKNTKSLKNTPNAKEMIESVKCPECGGDIALKRSRKGSFYGCNNYPKCNFLSNHKPIDKRCEKCHYLMSERIYRKKKVHECIKCKERVFLEEDNG
(1668) DNA topoisomerase 1 [Helicobacter bizzozeronii CIII-1]
1
MKANPKKLIIVESPTKAKTIANFLDQNYQVIASKGHVRDLSKYAMGIRIQEDKFIPKYIVDKDHEDIVEQILSLAKSASQIYIATDEDREGEAIGYHIAYLIKENQRTSQTKKMSANQILQETLDLEQQTNHAPSSNPIFHFPRIVFHEITKSAILHALKHPKTLDVYKINAQLARRLLDRIVGFSLSSLLASKIAKGMSAGRVQSAALKIVVDREREIQAFKPLIYYNIEGIFEGCIEASLESYLGEKIKKQSLTDAPDALKMVAHLRAQTYQVQEITHKNKTSPSPPPFMTSTLQQSASTHLGYGPSKTMGIAQRLYEGVATPEGMSGVITYMRTDSLNVAKEAIKAARDFISTTYGAPYLPNKPKTYTAKNKAAQEAHEAIRPTNLNFTPTIAKDYLKPEEYRLYTLIYNRFLASQMTDALFENQTLRLSCADGTFKASGRKLIFDGYHRVLGECDRDKLLPALQKDQSVRLDKLEAKKCSTEPPTRYSEASLIKTLESLGIGRPSTYAPTIALLANRSYVKLENKQLVPTEDAFVVIGILEKHFSEIVDAAFSAGLEDKLDAIASSKASWQQVLFDFYTPFMDKIEAGKAQIASQKSSVPTGEFCPECGLELVQRKGRFGEFVACSGYPKCKFVKPPSEQTPTPLEPCEKCGKPMVLKKGRFGEFVACSGYPQCKNIRSKAPQLKEEKVAGVCPECGGHVVEKRGRRGLFYGCANYPQCQFISNYPPSDQKCPECGYVLVFKAYKRKPSVWACLKCAFTRLADV
(1158) DNA topoisomerase I [Helicobacter bizzozeronii CIII-1]
3
MQKPDVIIIESPNKIKKIASITGAKVLATIGHFMELEGIEGENFKPKFAYRADKKQQIYAMIEQCKGKRVYIATDPDREGYAIGKMFYEKIKNVAKEVFRAEFHEITESGINKGLQSALLFANTNSNHYESFLARSVSDHYIGFTLSPYLGDCLQQRKGNSVGRVQTPCLKLIVDRDKEIEAFKALPESQKVSYQIQAKIYDTHNREVILRHCNGEGKEIKYESQEQALAMLAPLKECKVALVLDIKHFTISSPPPKPFITSSLLKVGSTQLGLSTQQIQEHAQKLFEAGLITYIRTDAETLSQEFLYKAEKFYQPIYTNLYERRAYKAKNSQAEAHEAIRITHCHKFEDTQDILAQAGIADNQAQALYTLIFQRTLESQGKSAVYAKQDLQFKIKDHFFKCSVRSLKQAGYLDMFRHTEQAKSAEQAENEQNAHLDLKTDSTISLLSLDIAPIQKHAKSAYVEASFIEVLEKNGIGRPSTYASYLPKLTQREYIQITPDKKRIVNATHKGKQVISVFEASPYSWIVDTQFTALMEELLDKIVRQECSYVEYMQMIAQRCPQMPSQTPREEYPTRAPRESQVKYVQDILRDLKMELPSEFADYARDDKITKAFLDKFIPKHKEAREKAKQEGHYLGDNTPASKPATAKQVAFAESLSQKHNVKLPKDYKSNMQVCSGFIEEWKGK
(1815) DNA topoisomerase 1 [Sulfurimonas denitrificans DSM 1251]
1
MNLIIVESPAKAKTIKNFLGKEYEVIASKGHIRDLPKSRFGITVDENSHLIPAYSVAKENAATVKEITTLAKKSDIIYIATDEDREGEAIGWHIAHAIKKDPAELPRIVFHEITKTAIENALLNARKIDMDMVNAQQARRILDRVVGYKLSPLLSSKIQKGLSAGRVQSSTLKLVVDREREIRAFVAEEYWTIDTLFAKDIEASLISHMGEKLSKLSITNKADASSIVKSVKEDSFIISKIETKERRSATPPPFMTSTLQQVASSKLGFTPKKTMMVAQTLYEGVKTPSGTSGVITYMRTDSLNLAHEALTAVRGLIESRFGKKYLPAEPKIYTKKAKGAQEAHEAIRPTMLAFTPEVAASFLKPDEIKLYRLIYERFVSCQMNDAVFEQQSIIFSGANNEYKAIGRKLTFDGFYALTGAEDKDKLLPSLSEGQSAQIQKIESTQHFTEPPARYSEAALIKKLESEGIGRPSTYAPTIATLSNRTYVTIEKKQIIPTEMAFTVTEILEKNFSNIVDLSFTANMEEKLDEIAEGQNDWQKLLSDFYGDFLAQVEEGKTNIVSLKMATPLGRACPKCGEELLLRSGRFGEFIACSAFPKCKYTEQVEGEKKEGEENAQSSSSDEICDKCGKEMVTKNGRNGPFLACSGYPDCKNTKSINVEEKTSETPCPDCGGKISLKNSRRGPFWGCENYPTCKFISKFEPSKYKCRESGCDGALAFRVFRGKEIYECIKCKAKTPAQEIVAE
(1164) DNA topoisomerase 1 [Nitratifractor salsuginis DSM 16511]
1
MKNLIIVESPAKARTISNFLGKDYKVVASKGHIRDLPKSSFGITVEEGKFIPKYTVPREASPTVKELKKLAKEAETVYIATDEDREGEAIGYHIAKAIGKDPEELPRIVFHEITKSAIQHALENPRRIDMQSVDAQQTRRLLDRIVGYKLSPLLANKIQKGLSAGRVQSAALKIVVDREREIKAFKPEEYWSIKGIFDKTVDADIYSFEGKKIEKMTLKNGEEANKIVESAKEESFKVASIETARRKSKTPPPFMTSTLQQAASTQLGFSPKKTMMVAQKLYEGVKTHKGTMGVITYMRTDSLNLAKEAVAEAREFIEKNFGEKYLPAKPKFYASKAKGAQEAHEAIRPTMTEFTPKLAAKYLAPDELKLYRLIYNRFLACQMTEAEFETQTILFAGEKSVFKATGRKLIFDGFYRITGYNEKDRLLPELKEEQPVELTEIKAEQHFTEPPARYNEASLIKKLESLGIGRPSTYAPTITILQNRKYIEIEKKRIHPTEIAFTVIEMLEKHFPEIVDSNFTARMEETLDKIAEGKEDWQKVLWEFYQPFIEKIAEGKKNIPSQKMAEPIGEKCPECGAELLKRKGRYGEFIACSNFPKCRYSRNIDGTEPEKPEETDEICDKCGAPMVIKNSRRGKFLACSAYPKCKNAKPLTPPKELAVPCPECGGKLIERQGRRGTFYGCANYPKCKFIANFEPVDKKCPECGYLMGVKHLKSGDVYVCFKCKHKVSAEAET
(367) DNA topoisomerase 1 [Campylobacter curvus 525.92]
1
MKDLIIVESPAKARTIKNFLSKNYDVIASKGHIRDLPKTSFGIKIEDDKFTPEYRVSLDHSKIVKEIKELAKGANEIYLATDEDREGEAIAFHIANAIGKEVSALPRIVFHEITKTAIDNALKHPRKIDMNSVNAQQARRLLDRIVGYKLSPLLNLKIQKGLSAGRVQSAALKIIVDREREIIAFKPVEYYSIDTKFKTDLDAELVKFEGKKIEKLTITNADRARYIVDALKNEKFSVREIESKDRKIQPSPPFMTSTLQQSASNRLGFSPKKTMMLAQTLYEGVQTHEGFMGAITYMRTDSLNLAKEAVEAARELIKNEFGKDYLPPKAVHYATSSKGAQEAHEAIRPTNLNFTPEIAAKFLQKDELRLYTLIYNRFLACQMSACVSQTQNLFVVSDNGEFKISGRKVLFDGFYRVYGDMDKDKILPNLNVGDEMKLESIKESQHFTEPPARYSEAGLVKKLESLGIGRPSTYAPTISLLTSREYVRVEKKQLIPNDVAFSMIGVLEEHFNDIVDSEFTSHLEEKLDLIAEDKADWQKVLSEFYYPFMDKISEGKTGIKSLKVATPIGEKCPQCGGELVKRKGRYGEFIACSNFPKCKYSRNIASQANDAGAQTTEPKAKKELVKLDVPCPKCGGVIVERFSRRGKFYGCANYPKCDFISNYEPTEHKCSECGSMMVKKELKKGTFLECTKCKHKVQIGEN
(1684) DNA topoisomerase 1 [Sulfurospirillum deleyianum DSM 6946]
1
MEKSLKNLIIVESPTKAKTIKNFLGKNYTVVASKGHIRDLPKSSFGIKIDNQTFIPEYRVPKDHASVVKEIKELAKEADQVYIATDEDREGEAIGFHIATAIGKDPKSLPRIVFHEITKNAITHALENPRILDESSINAQQARRLLDRIVGYKLSPLLSSKIQKGLSAGRVQSSTLKIVVDREKEIRAFKEEEFWSIDALFNKTIEASLVEFEGEKIEKMSIGNQERAYAIKEKLLKEAFHVALLEKKERESSPSPAFMTSTLQQSASSALGYSPKKTMMLAQTLYEGVKTHQGVQGVITYMRTDSLNVSKEAIEAAREQILSQYGKTYLPEKARFYANKSKGAQEAHEAIRPTILEFTPAIASAYLAPDELKLYALIYNRFLASQMNNARFESQTLIFESQSGKFKASGRKLLFDGFYKVYGDNDKDKLLPDLALKQEVTLSKLDANQHFTEPPSRYSEASLIKKLESLGIGRPSTYAPTISVLSARDYINIEKKQIVPTEVAFQVTELLEQHFPQIVDSSFTSTMEERLDLIAEDKEDWQAILWNFYEPFDAQVAKGKTEIQSQKVIVFTGEMCPECGKELVRRKGRFGEFIACSTYPTCKYTQNLKKVSESAPKEKVTLSVPCPECGGEIIERSSRRGKFFGCGNYPKCKFISNYEPTDKKCPECGYIMAKRELRKKEIYECIKCKHKEEA
(1786) DNA topoisomerase 1 [Campylobacter hominis ATCC BAA-381]
1
MKNLVVVESPAKAKTIGKFLGDNYNVIASKGHIRDLPKKTFGIKINEKHFEPVYEISEDHAKIVSEIKKLAKKADQIYLATDEDREGEAIAYHIATAIGKEPANLPRIVFHEITKTAIENAIKNPRALDTASVNAQQARRLLDRIVGYKLSPLLSQKIQKGLSAGRVQSSALKIVVDREREINAFKPEKFYTVNMIFKKDLEAEFVKFKNKKIEKMSIKTAKEADEIVQILCDEKFEVSKIESKDRKTNPYPPFMTSTLQQNASTALGFSPKKTMNLAQSLYEGVNAPNGGAITYMRTDSLNIAKEAIVSVRDMIKNEFGSEYLPKSANFYATKSKGAQEAHEAIRPTDLKFTPAIAAKSLPKDELRLYTLIYNRFVASQMNPCVSEIQNVFAKSGSSLFKILGRKVKFDGFYKIYGENDKDKILPDFKIGDELKVQNLKSVENQTEPPARYSEASLIKKLESLGIGRPSTYAPTLSLLISRKYVNTEKKQLVPTEIAFKIVEMLEQNFNNIVDSEFTSKMETKLDEIAEKSADWQEILADFYYPFMEKIAIGKKNIKSQKVAEPIGEKCPECGGELLKRNGRFGEFIACSNFPKCRYSRNLSGEQKIKKEPAKIGVKCPECGGEIVERVSKRGKFYGCSNYPKCNFISNYKPTNEKCPECGEMLFKKSLKKGDFLYCAKCKFQKAIDD
(1151) DNA topoisomerase 3 (DNA topoisomerase III) [Campylobacter hominis ATCC BAA-381]
3
MKLFIAEKPALAKSIAAGIDGEYKNGDGFFQKGENIITWAFGHLLELYMPEDYDENFKKWDLKDLPLKIDEFKYKPIQSSKEQLKIICNLIKRSDVDTIINCGDADEEGQILIDEILKYANNKKPVLRLLLHDLTEKGVRSELKNMKSNNDFSNLSECGFARSIADWIVGINLTRAYTTKAQNNGYKGVISVGRVQTPILGLVVSRDLEREGHKSSFYYTLTGKFKTHQAEILANLKTDEKITDENEANEIKNICLGKNGILNVTNENKLEYPPLPYNLLNLQADCSKKFNFKPDKTLKITQDLREKYKCITYNRSDCEYLPVNMWESSTNVLNSIKSNLSDFENIIKNADPNLKSRAFNDEFITAHFAIIPTETTFDFNSMSKDEQNVYKLISKRYIAQFYEPMQYLQTNIEILINDYKFTTSKKKITKNGYLSLFSGENDSEQKNDDEVENSFDLSLLESGNCQTLNIEINKKQTKPKPYYTMPTLLKDLTSISKYVKDEKIKTLLKEKDKDKKGENGGIGTPATRSEHIKNLFEREYIREEKKSIISTKKGRDLIALAPKILSTPDMTALWYEQQLEIQNGNLSKDDFLNRVFDEVEEQIELIKNNALLDKNFNGIDKTYPCKCGKGFLQKRHSQKTGKDFWGCSNWKNGCSEIYPDLNGKPNIPKYFCPKCGSALNRWKNKKGDGYYWSCSGWKTKGCQIGFINDKNGKPEI
(133) Reverse gyrase [Caminibacter mediatlanticus TB-2]
6
MLEAIYKNRCVRCLGDITSLRLSRGEFCDKCMQEIENLENCNELLNFKKFCEANKKLEEFNNFFKEKTGSTLNSIQKMWAKRYFLDNSFSLLAPTGIGKTTFGLLLSAFVNNSYIIFPTKLLVSQAIERFKLWGIEVLAYTGKKNEKEKIKNGEYNILITTTQFLYKNKKLINKNFDLVFVDDVDSILKSGKKIDDILGLLGFNEEDLQKAMELINKKEYEKISEIAKKKRGNLIVSSATANPKSKRILLFKYLLGFEVSRPNLTLRNIEDLFDEKFSWELSIEWIKKLGIGGLLFLPGNETKEKLYEYLEFLNNKGIKAYSYEEFNDHIDEFKKGECYFVGFASYRNPLARGIDLPQAIRYTLFVGVPKMEFNLNEDNFRSLYLILLSVFPYLMKNNLLDKKEAIEFQNYINFMKKYVFYTILHPKIEEKLRLISTKIKILIKKYENEIKNSPEISFDGEKIITADITGYIQASGRSSRFFNGHLTKGLSLVLVDNKKAFFSLQKKLKWFSEAQFKRVDEVNLEEILEEVEESRKIKKEIKLKTSFVVVESPTKAKTISSFFGKPSKRIINGVSVYEILLEDRNLVIAASVGHDFDLVEDEGDFGVIKKYIPIFKVLGEKDNILKALNLTSSEVEEVYIATDPDREGEKIAFDLTLNNKPFNLNIKRAEFHEITKYAFEDAIKNPREVDLNLVASQFVRRIADRWIGFKVSLYLQKLLKNAHLSAGRVQTPVLKWICERTSKLKEKIYIVRIIFDEIKVDFEFEDKKEAENFYNSLGEYIEIKKISSKEESLLEKPFNTSELLKEASIKLRFSPQKTMQLAQELFENGLITYHRTDSHRISSLGMSIAKEYIKENFGEEFIKLRSFEEGGAHEAIRPTSSMDSEDLRSFIAFKNLELNNEHIKLYDLIFRKFIASQMKEAKVLKETYDILGKNEEFITKIIEDGFNLIYPIKVYNVNEGKKKIEKLKLQKSKYPPYTYADIIELMKQKGIGRPSTYAITIEKLLDRKYVVEKNGYLFATKLGFKVIDIVFNSEYKEFLDEEYTAFLEEIMDKVEKGEVNYKIILEELYQKVILNQK
(1564) DNA topoisomerase 1 [Caminibacter mediatlanticus TB-2]
1
MAKKLIIVESPSKARTIKNFLGKEYEVIASKGHIRDLPKTSFGIKIEEDKFIPQYRVTKDHQSVAKELKEKAKKAETIYIATDEDREGEAIGFHIAHVIGKDPSSLPRIVFHEITKTAIKNALKNPRKLDIDRVNAQQARRLLDRIVGYKLSPLLNKKIQKGLSAGRVQSAALKLVVDREREIKEFIPKEYWSIEGIFKEVEGNLIKYNGKKLEKFDLKTRDEAEKIVNELKPLEYEVSKIEKKTTTTKSPAPFMTSTLQQVASSELGFSPRKTMQIAQKLYEGVKTPVGETGIITYMRTDSLNIAKEAQEAAINFIKENIGSEYAEAKTYTTKNQTAQEAHEAIRPVDVRLTPDDLKNYLSKDELKLYSLIYNRFLASQMKDAKFETQNIYLTNEKGEFKISGKKLIFDGFYKVYGKRGADTLLPEFKEGEKLKPEEIKATQHFTKPPERYTEASLIKKLESLGIGRPSTYAPTITLLQNRNYVEIKDKKLHPTEIAFNVIETLEKHFPDIVDAKFTANMEEMLDEIARGNKDWQEMLKEFYNPFMKLIEKGYEEIPSQKIAKPTGELCPECGNPLVIRKGRFGEFIACSNFPKCKYTRPIEEKEEKKVDVKCDKCGADMVIKRGKRGEFLACSNYPECKNTKPLNPPEVLEDVKCPECGGDIIKRKSRRGEFYGCGNYPKCNFISKYRPVNEKCDECGYMMAKRTYRNKEVLECIKCKARKEI
(1046) DNA topoisomerase 1 [Arcobacter nitrofigilis DSM 7299]
1
MKNLVIVESPAKAKTISKFLGSEYKVMASMGHVRDLPKSKLGFDPADNFKPQYLISTDKRKVIADLKKEITKDTTIYLAADEDREGEAIAWHLIPALKVEKNPLKRIVFHEITKGAILKALENPREVNQNLVDAQQARRILDRAVGYELSPLLWKKVRYGLSAGRVQSVAVRIIVDRENEIRAFIPEEFWKIKADFINPQLNTELAKIDGKVKKIKNEQEAKVIEASINQGEFELFDIDESESKRNPAAPFTTSTLQQEASRKLGYSVKQTMVIAQQLYEGNIQNIPNHTGGLITYMRTDSLNLSTVATSAAKEVIEKTYGAEYSLKSPRVYKSKAKGAQEAHEAIRPVDLSLKPSMIKAYVDNAQFRLYSLIWKRTLATQMQTAKIANTTYKISAGKDKEYEFQVKGQRIIFPGFMKVYTEGSDNPESALDSSEKILPSIKVGTKLDLEKLDLEQNFTKPPARYTEASLVKKLESEGIGRPSTYAPTISTIQAREYITKSEDKKLIPTPTGEIVNSFLTDHFPNILDLGFTAKVEEEFDDIADGKIAWQQVMKDFYGDFKKTIDEKEESVNKEDYLQIREIGTDPKSGKPVSARVGRFGPFVQIGTKDDEEKPLFVAIPAHLNMDTITMDEAMFLFTLPRVVGQTADGEDIKANIGRFGPYLQVKTKYYSLKEDDPYKIELPRALELIKQIDEEKAKATIKNFEKEKIQVLDGRYGPYIKQGRKNYKIPKGKDAASLELEDCLSIIENDSKTSKRAPAKKTAAAKTTTKTATKKAPAKKAPVKKTTTKKTTAKKEK
(974) DNA topoisomerase 1 [Helicobacter mustelae 12198]
1
MKKLIIVESPAKAKTIQNFLGEEYQVIASKGHIRDLPKMRFGIHIKQESFEARYVIDEDHQEIAKNIKELAKQSSQVYIATDEDREGEAIGYHITQAIAKDPQSFPRIVFHEITKTAIQDALANPRNIDMNKVNAQQARRFLDRIVGFKLSSLVSSKIAKGLSAGRVQSAALKIIIDKEREIQKFIPLDYYSIEGNFLGLSAQLIAYQGKKLKEQEITEEARAKQMQENLQKNLYTIGDLQKKSKKSPTPPPFMTSTLQQSASNLLGYSPTRTMSIAQKLYEGVQTHQGYMGVITYMRTDSLNIAKIAQDQAREHILKAFGQAYLPKKPKIYATKNKSAQEAHEAIRPTNLDFTPEIAKNYLKNEELKLYTLIYHRFLASQMEDAILESQSITFIGEEGEFKANGRRLLFDGFYKVLGNEDKDKLLPELEVGAKIKPQSLEVNKHTTQPPARYSEASLIKILESLGIGRPSTYAPTIALLNSRYYIKIENKQIHPQESAFKVIEMLENHFDKIVDATFSASLETKLDEIAENKQNWQKFLWDFYEPFMEQINAGKTDIASQKMKIPTGEYCPQCGSELLLRESRYGEFTACGAYPKCKYIKPQEEEGEKDPESCEKCGKPMVTKMGRNGSFLACSAYPECKNTKSLLAKPSQQKVLEGVACPECGGEILLRNSRRGAFYGCSNYPKCNFLSKFPPTNHKCPECNYLMNDRTYRGRAIFECIKCKHRVDQ
Family distribution
Taxonomy tree
Epsilonproteobacteria