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Taxon : Lactobacillaceae
Informations
Name
Lactobacillaceae
Rank
family
# topoisomerases
27
Lineage and sub-taxa
Lineage
Bacteria
>
Firmicutes
>
Bacilli
>
Lactobacillales
>
Lactobacillaceae
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(937) Putative DNA topoisomerase [Lactobacillus brevis]
3
MSIVVLTEKSSQIDPYAKALGTPKKKQGSVWVHSALLNADVQFVAASGHLFKLDGPEDYNDAWRDRSNYEQLPMVPQKFKARIKDARARASFNRIKQAITAADEVILATDPDQQGEVIGREILQRIPGGMEKCQRRLLNSSLTAKGALRSFENLVPMAKQEHLGAAGFLQNRLNWLIGMNLSRVGGIQLKKRGYYFPVAAGTVKTPTLALVVANDQEIKHFKEAPYWQIELTDQANQQRFKAQPSRHFSIEDEAKQALAQVTDTLTIKSVDQVEQHRLPPKLFNLTALQGYAAKKWGYSGTEVLETMEHLYKDLAITSYPRTESTVIEDAEFDYLKANFNDYAATLNLKMAMQVPDARPEFVKTTTDGHPALIPTDKVADLSQLTERERRCYGAVVKRTLLMFAGDCVLDKTVVKGTLGTEQIYEATGQQFKDLGWTEFDVVKTENRELPSYQQGQQVKIETSLVEGKTKVPQRITEGMLFSKLFPKYNLGTPATRAGIVSELIEKNHYIEVKGKRRELYPTSEGINMVAFWQGTLLTDLKLAKSWQDIFDKVIQGNMQPDRYQEQMVEALTDIVADYRTKKPDLPIAPKPHTSYEFKPLTPAVKCPKCHRGELGLLVATNAKNNQFYACSQKKCHFSLPNKYSGIALTSELVRQLATKKQTDWLPEVKSSQGKVYRNQVAFILAEKLKLQWTFKQTAKKTERTD
(815) DNA topoisomerase 1 [Lactobacillus johnsonii NCC 533]
1
MPTKRKNKKNLVIVESPHKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGVDVEHDYEPKYISIRGKGDTIKELKSEAKKAKYVYLASDPDREGEAIAWHVAHALNLDPKEHNRVAFNEITKDAVKNAFKNPRTIDMDIVDAQQARRVLDRLVGYSISPILWQKVKKGLSAGRVQSIALKLVIDRENEIKNFKPEEYWTIDADFEKGSEKFKGAFYGIKGKKQELPNNEAVQDVLKRIDKRKNFEITKVVKKERRRQPAAPFTTSTMQQEANKRLGYRTRRTMRIAQSLYEGVNLGKGSVGLITYMRTDSKRIANVAKHEASKFIHEEYGENYAAVKPQHFKNDADAQDAHEAIRPTSAFRTPASVKEYLTTEEYRLYTLIWSRFIASQMTPAVYDTVRADIEQNDVTFRTTGSKLKFAGFTKVYDNQKEKSNELPELNEGDKVKLKKTDDRQHFTQPPARYTEASLVRTLEENGVGRPSTYAPTIDTIQKRYYVKLEGRSIVPTELGEIVDKLIEEFFPDIVNVDFTAQLENDLDGVEVGKKNWIKVVDEYYKPFSKELDKADQQIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVTCPKCGKGEVIEKKSKRNRKFYGCSRYPDCDFVSWDQPIGRNCPNDGHFLVQKKNKKGLVILCPNGDYREEPEEN
(809) DNA topoisomerase 1 [Lactobacillus acidophilus NCFM]
1
MPTKAKSKSKTKKRKKILVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHVAHALDLDENAKNRVTFNEVTKDAVKESFKHPRSIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWSIDAEFSKGKDTFKSSFYGIDGKKKELPNNDAVKEVLAKIDKRKNFEVENVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKEGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVMFRTTGSKMKFPGFTKVYDNQQEKSVDLPDLQEGDKVKMTKSDNKQHFTLPPARYTEASLVRALEENGVGRPSTYAPTIDTIQRRYYVKLDGRSIVPTELGEIVDTLIEEFFPDIANVDYTAHLENELDEVEDGKKEWVHVVDEYYQPFKKELTKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVVCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVVLCPNGDYKEEPQEGETDK
(545) DNA topoisomerase 1 [Lactobacillus gasseri ATCC 33323]
1
MPTKRKNKKNLVIVESPHKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGVDVEHDYEPKYISIRGKGDTIKELKSEAKKAKYVYLASDPDREGEAIAWHVAHALNLDPKEHNRVAFNEITKDAVKNAFKNPRTIDMDIVDAQQARRVLDRLVGYSISPILWQKVKKGLSAGRVQSIALKLVIDRENEIKNFKPEEYWTIDADFEKGKEKFKGAFYGIKGKKQDLPNNEAVQDILKQIDKRKNFEVTKVVKKERRRQPAAPFTTSTMQQEANKRLGYRTRRTMRIAQSLYEGVNLGKGSVGLITYMRTDSKRIANVAKHEASKFIHEEYGANYAAIKPQHFKNDADAQDAHEAIRPTSAFRTPASVKEYLTTEEYRLYTLIWSRFIASQMTPAVYDTVRADIEQNDVTFRTTGSKLKFAGFTKVYDNQKEKNNELPELNEGDKVKLKKTDDRQHFTQPPARYTEASLVRALEENGVGRPSTYAPTIDTIQKRYYVKLEGRSIVPTELGEIVDKLIEEFFPDIVNVDFTAQLEDDLDGVEVGKKNWIKVVDEYYKPFSKELDKADQQIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKVGVTCPKCGKGEVIEKKSKRNRKFYGCSRYPDCDFVSWDQPIGRNCPNDGHFLVQKKNKKGLVILCPNGDYREEPEEN
(1128) DNA topoisomerase [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
3
MTTVILAEKPSQARAYAVAFTQSQKGEGQIKVADPILPADTVITYGFGHLVEMALPEAYDASYKRWSLKKLPIFPDQYKYLVSRDKKKQFNIVANLLKRADTIVIATDSDREGENIAWSIMRQAGIDLKQKHLFRLWINSLEKAAIREGFQNLRPGWDYYYRYKEAQTRQISDWLVGMNGSPLFTLLLRKQGIKGTYSIGRVQTPTLYMVYKRDQEIANFKPEKYWLLMADFWQGRKKFTGRLLPETKFKSPAELEQFLLAKGGSLGKQTGRVAKVDKEQKSQASPRLFSLSSLQTEANRRYHASASQVLQAVQNLYENKFLSYPRTDCNYITDNEYAYLAQNLDRYQGLLPNSAEVKEQMKPLKAEKRYVDSGKVQEHHAIIMTKTVPSQAQMGKMSKLEGQVYGLVLRRTLEMFLKAYVYEKTTALINVGQLTFKASGNVSVNLGWKILEGPVKDAQLPSLEVGQELTAKLKEQEEETKPPAKFTEGSLITAMKTAGKTLDDEDAQATLKDVEGIGTEATRASTIEILKKRGYMQSRQNKLSVTPEGTILCKVAEAEPLLVSAQMTAQWEKALKQVGAKERSQDNFLGQIKKFISKMITEVPGKIQVDQGLQEEAQTRQAKTAAIGPCPVCKQGEITDKGKFYGCSNYRGGCHFTLPKKFAGKNMGKRIVKTLISKGKTDKLDGFISKKSGQRYSAKLQLEGDKLSLVFD
(1067) DNA topoisomerase 1 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
1
MPATAKEDKSKSSKKTTAAAKKSSPKRKKSKVKKDLVIVESPAKAHTIEKYLGRKYRVIASKGHIRDLPKSQMGVDIDHDYQPKYISIRGKGDTIKELKAEAKKANKVYLASDPDREGEAIAWHVAHVLGLDEKEANRVTFNEVTKDAVKDAFNHARTIDMDTVNAQQARRVLDRLVGYSLSPILWSKVKKGLSAGRVQSVALKLVIDREKEIKAFKPVEYWTIDAEFAKGKDKFQASFYGEEGKKTELPNNEAVQKLLAKFDKKQPFTVSKVVKREVRRQPAAPFTTSTMQQEANRRLNFRTSKTMNIAQHLYEGISLGKEGTVGLITYMRTDSKRISPVARQEAAQFIVEEYGSDFAVKKERHFKNQGDAQDAHEAVRPTSVYRTPKSLEKVLTKDELRLYTLIWSRFVASEMTPAVFDTVRYDLTQNGVTFRASGSVMKFAGYTKVYDNRSEKNVALPALEEGDEVKLTKSDNKQHFTQPPARYTEASLVRALEENGVGRPSTYAPTIQNIQSRNYVKLEGRAIVPTELGEIVDGLVEQFFPDITSVDYTAKLEDELDEVEEGKKDWVSVVDQYYKPFSKELEKADSEIQKIQIKDQPAGFDCEVCGAPMLVKMGRYGKFYGCSRFPDCRHTQTIVKKVGVTCPKCGEGEVLEKKSKRGRKFYGCSRYPDCDFVSWDKPISRVCPHDGHFLVEKKRKDGMVVLCPNGDYKEEPREEQGEAAE
(347) DNA topoisomerase 1 [Lactobacillus buchneri NRRL B-30929]
1
MATSTKTKPKAKAKSKTKRKSPKKNLVIVESPAKAKTIEKYLGRSYKVVASKGHVRDLPKSKMGVDIDHDYEPHYISIRGKGDTIKELRSAAKKAKKVYLAADPDREGESIAWHLQHILDLDPNEDNRVVFNEITKDAVKESFKHPRNIDMNLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALWLIIQREKAIKDFTPEEYWSIDSEFKKGRSKFKAAFYGLNGKKKELPNNEAVQKVLQQLDPKGDFDITKVTRRERKRQPQPPFTTSTMQQEANRKLNFRTRKTMMAAQQLYEGINIGKEGSQGLITYMRTDSTRISVIAKHEASQFLHEKYGAEYAATKPIKGKLPEGAQDAHEAIRPTSVFRTPASLKQYLTRDQFRLYQMVWSRFVASQMTPAIMDTMAVTIEQNNVTFKANGSKMKFDGFLKVYGDSKEKDNLLPDLESSDVVKLVKNNPDQHFTQPPARYSEATLIKALEEKGVGRPSTYSPTIDTIQRRYYVKEVGRRFEPTELGEIVNKIIVEYFPDVVNIDFTANLEGKLDQVEEGKENWIKLVDTFYKPFSDEVDAATKNMEKVQIKDEPAGINCEICGAPMVIKMGRYGKFYACSRFPDCRNTKAIVKEIGVICPKCHKGQVIERKSRKNRIFYGCSRYPDCDFVSWDKPIGRDCPKDGHFLVEKRVKGGTQVVCPNGDYEEPAQK
(273) DNA topoisomerase 1 [Lactobacillus helveticus DPC 4571]
1
MPTKAKSKSKTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHIAHALNLDENAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWTIDAEFAKDKEKFKSAFYGVDGKKKELPNIDAVKDVLAKIDKKKNFTVEKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKNQRHFKNQEDAQDAHEAIRPTSVYRTPESLKDVLTKEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKMKFAGFTKVYDNQQEKNVELPDLQEGDQVKMTKSDNKQHFTLPPARYTEASLVHALEKNGVGRPSTYVPTIDTIQRRYYVKLDGRSIVPTELGEIVDTLVEEFFPDIANVDYTAHLENELDEVEDGKKQWVNVVDEYYQPFKKELNKADSEIQKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVVCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVTLCPNGDYREEPQENEDK
(1107) Uncharacterized protein [Lactobacillus reuteri SD2112]
1
MATKTTKSTAKKTTRRRSKIKKNLVIVESPSKAKTIGKFLGRSYKVVASLGHIRDLPKKPDGGRY
(1379) DNA topoisomerase 1 [Lactobacillus amylovorus GRL 1112]
1
MPTKAKSKPKTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFDDNYKPKYISIRGKGDTIKELKSEAKKAKEVYLASDPDREGEAIAWHVAHALNLDENAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKEFKPKEYWSIDADFKKGKDSFKSAFYGVDSKKKELPNIDAVKEVLAKIDKKKDFEVAKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRISPVAQQEASKFLHEKYGAEYAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFVASEMKPAVYDTVRADIVQNGVMFRTTGSKMKFAGFTQVYDNQQEKNVDLPDLEEGDKVQMTKSDNKQHFTQPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLEGRSIVPTELGEIVDTLIEQFFPDIANVDYTAHLEDELDEVEDGKKQWVNVVDEYYQPFKKELDKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVVCPKCGKGQVVEKKSRRNRKFYGCSRYPDCDFVSWDKPIGRNCPNDGHFLVEKRSKKGPVILCPNGDYREDPQEDEIDK
(214) DNA topoisomerase [Lactobacillus salivarius UCC118]
7
MKKLILAEKPSVARDIGRILNANEKKKNYLEGKNYIITWALGHLLGLKMPEDLNKKWEKWQLETLPMLPKFIGIKPLPKTRGQLKTIESLVKRKDINEIVIATDAGREGELVARWILQYVHANKKVTRLWISSQTDKAVKQGFKELKPAEKYDNLYESALARATADWLVGLNVTRALTVKYQDNLSAGRVQTPTLALVRRQEEKIEKFMPQKYYRIALRIGKQTAYMKQKNIYAIKERDEAEKKKRHLDNFKGQIKDINSKIKREPAPLLYDLTELQREANKRYGYSAKKTLSLVQSLYEIHKVVSYPRTDSRYLSNDIKATLMERLQAIRKYDSRAEEAIKNKAKVILKKVFNDSKVTDHHALIPTEQVPNYSKFSADEQKIYNLIVSRFLGIFAQPYTVEELRVVVTFDKDEFIFVGKKVLDYGWKNKDAAEEVVLNLKKDTAVSPNFTVEEKLTTPPAPLTEAGLLAQMEKFGLGTPATRAEIIEKLVKSELMERTGHALRVTPKGKQLLNLVNKELVSPKLTAKWEKQLEDIAHGKMKSQKFIGDIKNDTKRLVSEVKNSKEDYKDFSLTKKRCPECNSFLKVRKTRDGEIYVCSNPECNYRRRKDAKVSNHRCPQCHRKMLIVEGKNGKYFRCKYDGTTEKMTVGKKSKKMTKHEERRLLKKINQDDEPQESPLALALKAAMGKNE
(1686) DNA topoisomerase 1 [Lactobacillus salivarius UCC118]
1
MPTTQKPKKKTTKRTRKKNLVIVESPSKAKTIEKYLGSNYKVMASLGHIRDLPKSKMGIDVENGYEPHYISIRGKGDVIKELRKEAKKASHVYLAADPDREGEAIAWHLSYLLGLNPEDKNRVVFNEITKDAVKNAFKSPRSIDMNLVDAQQARRVLDRLVGYSISPLLWSKIKKGLSAGRVQSIALNLIIQREKEIRDFKPEEYWTIDAKFKKGRTKFEADFWGVDNKKKKLSNEKDVKEVIEKIDKDKPFNVINIEQKERKRMPPLPFTTSAMQQTANNNLKFRTQKTMMVAQQLYEGINIGRGGAVGLITYMRTDSTRISSVAKHEAAVFLHENYGEEYAASKPRQGKLSENAQDAHEAIRPSSVERTPEKMAKYLDKDQLKLYTLIWSRFVASQMTPAVFDTMRVDIEQNGVQYRANGSKMKFPGFIKVYKAATSKDNLLPELKVGDEVDMVQNQPNQHFTLPPARYSEATLIRTLEENGVGRPSTYAPTLSTIQKRYYVKLVSRKFEPTELGEIVNSMIEECFPDILNVDFTAHLEDQLDDVEEGKEEWVRIIDEFYQPFSKEVDNAQVKMDKIKIKDEPAGIDCEICGAPMVIKLGRYGKFYACSRFPDCRNTKAIVKEIGVVCPKCHKGQIIERKSKKNRVFYGCSLYPDCDFVSWDKPIGRDCPKCSHYLVEKKTKKGMQVKCSNCDYEEAIQNN
(1657) DNA topoisomerase 1 [Pediococcus claussenii ATCC BAA-344]
1
MPTAKKNLVIVESPSKAKTIEKYLGRSYKVIASLGHIRDLPKSKMGVDIDNNYDPHYISIRGKGDTIKKLRTEAKKAKKVYLASDPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDAVKNAFKTPRSIDTSLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALSLIIKREQEIRDFKPEEYWSIDSEFKKGRSKFNASFYGTGGKKKALKNEKAVQKILKLINPKDDFDVTSVKRKERKRFPSPAFTTSSLQQEANKTLNFRTRKTMMAAQQLYEGINIGKEGTVGLITYMRTDSTRISDIAKHEASVLIHEKYGAEYAAIKPRKGKMPEGAQDAHEAIRPSSVNRTPEDLKEYLSKDQYRLYNLIWSRFMASQMTPEVSDTMAVTIEQNDVQYRANGSKTKFEGFTKVYKTNKEKDNSLPAMEEGDKVKLVSNNPNQHFTQPPARYSEANLVKALEENGVGRPSTYAPTLDTIQKRYYVKLESRRFEPTELGEIVNDIIYEFFPDIVNIDFTAHLETELDEIEEGKEDWVKVVDGYYKPFSKEVDTAQEQIEKVQIKDELAGFDCEVCGSPMVVKMGKYGKFFACSRFPDCRNTQAIVKEIGVTCPKCGIGQIIERKSKRGRLFYGCSRYPDCDFVSWDKPVGRKCPVCHSFLVEKKIKGGKQVVCPNGDYEETPQK
(1042) DNA topoisomerase [Pediococcus claussenii ATCC BAA-344]
7
MKKKLIITEKPSVATDLARVLGVEQKNKTYYEGNNYIITWAYGHLLTLKLPEDINKDWQNWDLNDLPIIPKNIGIKPLPKTKQQLKAISRLAKRTDVESAIIATDSGREGEAVARYILEWIRFNKPVERLWISSQTTKAIREGFSNLRPAEQFDDLYASALARGKADWLVGLNVTRALTTKYKDNLSAGRVQTPTLSFIWKQEQEINSFRPHKFYKIYLVYQGQTADLLLKNSEQFETREQAEKVVQGLQKKSGLVEDLKVKQNMQDAPLPYDLTELQRTANSMYAFSAKKTLSIVQSLYEVHKIVSYPRTDSKYLSTDIKDTLKERLSALSGFDSQAKAYLRRGAKIVQRSVFNDQKVTDHYALIPTEESVQPAKLSSDELRIFRLIEKRFLGLFAEKFITETTNTTIGFGSAKFVFKQTRVVKPGWRFDLETETKKTKVQLKLKQQIEGQFIIKEKLTTPPKPLTEGTLLGKMEKFGLGTPATRAEIIEKLTQSELVKRTNGALITTPKGQQLLKLVNKSLASPDLTSKWEKSLESIAHGKVNYMDFVKDVEKETRRLVSEIKTSEIEYRDFGVTNKLCPECGYALKERNSRDGKILTCSHCGYRRRKDPKVSNHRCPQCHKKMVILEKNGQSYFRCLNDGTTEKMLDKKERKKKISKKEERKLLSKINNEDPEESPLAIAMKKAMEK
(995) DNA topoisomerase 1 [Lactobacillus plantarum WCFS1]
1
MAASTTKAKPAAKRKTATKTATKRKSKTPAKKLVIVESPSKAKTIEKYLGRSYKVVASLGHIRDLPKSKMGVDVDNDYEPHYISIRGKGDVIKGLRKEAKKAKAVYLASDPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDTVKNAFKEPRSIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSIALDLIIQRENEIKAFKPQEYWTIDSEFQKGRSKFMASFYGTHGKKQPLDDNDAVQKILGQLDRNGDFNVVKVVKKERKRFPAPPFTTSTMQQDANRKLNFRTRKTMMAAQQLYEGINVGGKEGSVGLITYMRTDSTRISSIAKHEASQFLHKEYGAEYAATKPVKGKLPEGAQDAHEAIRPSSVFRTPASIKDYLTKDQFRLYQLIWSRFVASQMTPEVLDTMAVTIDQNDVQFRANGSKTKFAGFTKIYDKTEKNNVLPDLSEGDVVKLSKTDPQQHFTQPPARYSEANLIKALEENGVGRPSTYAPTLDTIQRRYYVKLEARRFVPTELGEIVNDIIQEYFPDVVNVGFTASLEEQLDATEEGKENWVKVVDSFYKPFSKEVATAEESMEKIQIKDELAGFNCDICGAPMVVKMGRYGKFFACSRFPDCRNTKPIVKEIGVVCPQCKKGQVIERKSKKNRIFYGCSRFPDCDFVSWDKPVGRDCPKDGHYLVEKKVKGGKQVLCPNGDYTENVQK
(1615) DNA topoisomerase 1 [Lactobacillus rhamnosus ATCC 8530]
1
MADKKLVIVESPAKAKTIEKYLGRTYKVVASLGHIRDLPKSQMGVDVENNYEPKYISIRGKGDVIKSLKKDAKKASRVYLAADPDREGEAIAWHVSHILGLDPNAKNRVVFNEITKDAVKNAFKTPRGIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKNFIPEEYWSLDAEFQKGRSKKFSASFYGIKNKKMALKNNEAVQKVLSQIDKAKPFSVTNVVKKERKRFPAPPFTTSTLQQEANRKLGFRTRKTMMLAQQLYEGINLGGKLGTVGLITYMRTDSTRVSNVAKTETSHYLHEKYGEAYAAVKIRQGKLQEGAQDAHEAIRPTSTLRTPESLASVLDKDQMKLYRLIWSRFVASEMTPAIIDTVAVTLNQNDVTFRANGSQMKFEGFTKLYVSSRDSGEKDNVLPPLAVGDAVKMLKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYAPTIETIQKRYYVKLNARRFEPTELGEIVNSLIVEFFPDIVNIKFTANVESELDSIETGEANWVKVIDQFYKPFEKEVAHAETGIEKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKAIVKEIGVICPKCHKGQVVERKSKRNRVFYGCSRYPDCDFVSWDKPVGRDCPVCGHFLVEKKSKAGTQVVCPNNDYKEALQKA
(361) DNA topoisomerase 1 [Lactobacillus crispatus ST1]
1
MPTKAKSKTTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDDYKPKYISIRGKGDTIKELKSEAKKAKDVYLASDPDREGEAIAWHVAHALNLDEKAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWSIDAEFAKGKETFKSAFYGVDGKKKELPNIDSVKDVLAKIDKKKDFVVDKVVARQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQQEASKFLHENYGAEFAAKSQRHFKNQEDAQDAHEAIRPTSVYRTPESLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKLKFAGFTKVYDNQQEKNVDLPDLEEGDKVKMTKSDNKQHFTLPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLDGRSIVPTELGEIVDGLIESFFPDITDVDYTARLENELDEVEDGKKDWVHVVDEYYQPFKKELNKADSEIEKVQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIIKEIGVVCPKCGKGQVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKHSKKGPVILCPNGDYREDSENEKNN
(1845) DNA topoisomerase [Lactobacillus sakei subsp. sakei 23K]
7
MRKKLVITEKPSVAKELAKVLGTNQKTKTYFEGDQYVITWAFGHLLSLQLPEDIKKEWQQWRLEDLPIIPKHIGLKPLPKTGGQLKAISHLAHRQDISGAVIATDSGREGEAVARYILEWIKFDKPVERLWISSQTTKAIKDGFANLKPAKQFDNLYASALARGHADWLIGLNVTRALTTKYEDNLSAGRVQTPTLAFVNETAQQISRFKPEKYYTIQLKVGQEQATLQMAKPQGLKDRAQAETLVAKLKQAQGKVGSVKTSQKSQAAPLPYDLTELQQVANAMYGLSAKKTLSLIQSLYEIHKVVSYPRTDSKYLSTDIEGTLKERLSALVKFDPRAKQYLGQGAKVKQPAVFNDRKVTDHYALIPTEEPVRAEKLSTDELRMYRLIVERFMGLFADQYVTAVTKATVQFGDHTFTFKQTKVVQQGWHADSKETPTTSVDWQEGAVVPADFSIKEQLTSAPKPLTEGTLLGKMEHYGLGTPATRAEIIEKLVRSELLERRGHSLAVTPKGQQLLKLVNKTLVSPELTGKWENSLEAIARGQENQKAFITEIEAATKTLVSEIKKSETEYHDFAITNKKCPECDHPLKERNTRDGKVYVCTNCHYRRRKDPKVSNHRCPQCHKKMVIIEGQAGAYFRCLNDGTTEKMLDKKDCKKKISKHEERRLIQKVNQEEEPAESPLAAALRKAMEK
(1150) DNA topoisomerase 1 [Lactobacillus sakei subsp. sakei 23K]
1
MAGKNLVIVESPAKAKTIEKYLGRNYKVVASKGHIRDLPKSQMGVDFENNYEPKYISIRGKGETIKELKKHAKKADHIYLAADPDREGEAIAWHVSHILKLDPTDKNRVVFNEITKDTVKSAFKNPRSIDMKLVDAQQARRVLDRIVGYSISPLLWQKVKKGLSAGRVQSVALKLVIDREQEIKAFKPEEYWSLDAEFKKGRSKFKASFYGLNGKKTALGNNDAVQDVLKQIDKTQPFTIEDVKKRERKRFAAAPFTTSSLQQEANRKLNFRTRKTMMQAQQLYEGINLGGKEGTVGLITYMRTDSTRISTGAKHEASQFIHDNYGEEYAAVKAHKTKNPEGAQDAHEAIRPTSVMRTPKSLKDVLTNDQYKIYNLIWSRFVASQMTPAVFDTVAVKINQNNVLFKANGSQMRFPGFTKLYVSSRDTEDSAKDNLLPELAVGDEVKLAKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYSPTIETIQRRYYVKLNAKRFEPTELGEIVNNLIVEFFPDIVSIDFTADLEHRLDEVETGQENWIKIIDNFYQPFEKEVEKASVQIEKVQIKDEPAGFDCDICGAPMVVKMGRYGKFFACSRFPDCRNTKAIVKEIGVTCPKCGKGQVIERKSKKNRLFYGCDRYPDCDFVTWDKPVGRNCPKCEHYLVEKKIKGGKQVICPNGDYEEAVQK
(486) DNA topoisomerase 1 [Lactobacillus casei ATCC 334]
1
MADKKLVIVESPAKAKTIEKYLGRTYKVVASLGHIRDLPKSQMGVDVDNDYEPKYISIRGKGDVIKSLKKDAKKASKIYLAADPDREGEAIAWHVSHILGLDPKAKNRVVFNEITKDAVKNAFKTPRGIDMDLVDAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSVALKLIIDRENEIKNFTPEEYWSLDAEFQKGRSKKFSASFYGLKNKKQALKNNEAVQKILGQVDKTKPFAVTNVVKKERKRFPSPPFTTSTLQQEANRKLGFRTRKTMMLAQQLYEGINLGGKLGTVGLITYMRTDSTRVSNVAKTETSHYLHEKYGEAYAAVKIRQGKLQEGAQDAHEAIRPTSTLRTPDSLTAVLDKDQMKLYRLIWSRFVASEMTPAIIDTVAVTLDQNGVTFRANGSQTKFEGFTKLYVSSRDSDQKDNILPPLAVGDDVKMLKTDPAQHFTQPPARYSEANLVKALEENGVGRPSTYAPTIETIQKRYYVKLNARRFEPTELGEIVNSLIVEFFPDIVNVKFTANVESELDRIETGEADWVKVIDQFYKPFEKEVAHAETGIAKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPNCRNTKAIVKEIGVVCPKCHIGQVVERKSKRNRVFYGCSRYPDCDFVSWDKPVGRDCPVCGHFLVEKKSKAGTQVVCPNNDYKEALQKA
(1100) DNA topoisomerase 1 [Lactobacillus ruminis ATCC 27782]
1
MESPSKAKTIEKYLGNRYKVMASLGHIRDLPKSKMGIDVENNYEPHYISIRGKGDVIKELRKEAKKADHVYLAADPDREGEAIAWHLSYLLGLDPKDKNRVVFNEITKDAVKNAFKTPRAIDMNLVDAQQARRALDRLVGYSISPLLWSKIKKGLSAGRVQSIALNLIIKREKEIRNFKPEEYWTIDAEFKKGRSKFEGSFYGIDGKKTALQNNDAVKSVMERIDTKKPFTVDNVEKKERKRQPPLPFTTSTMQQVANNNLKFRTQKTMMVAQQLYEGINIGRSGTVGLITYMRTDSTRISEVAKHEASEFIHSEYGENYAAIKPRQGKLAEGAQDAHEAIRPSSVLRTPKSLEKYLDKDQMKLYSLIWSRFVASQMTPAVIDTMRVDLEQNGVSYRSTGSKLKFDGFTKVYADSKHKDNMLPDLENGDEVIMSRNQPNQHFTLPPARFTEAALIKTLEENGVGRPSTYAPTLNTIQKRYYVKLAARKFEPTELGEIVDNMIGKCFPDILNVKFTAKLEDQLDEIEEGKQEWVKVVDEFYKPFSTEVKTAEEKMAKVKIKDEPAGFDCEICGAPMVVKMGRFGKFYACSRFPDCRNTKAIVKQIGVKCPQCKRGEIIERKSKKNRLFYGCNRYPECDFISWDKPIARDCPKCGHFLIEKKTKQGMQVKCPNNDYEEAIQK
(242) DNA topoisomerase [Lactobacillus ruminis ATCC 27782]
7
MKQLILAEKPSVARDLSQILGATEKHKDYFEGDGVIVTWALGHLLGLKMPEDLNKDWQKWQLETLPMLPKFIGTKPLPKTRHQLQAIERLAKRSDVKEAVIATDAGREGELVARWILQYVRFNKPVKRLWISSQTTKAVKEGFARLKPASDYDDLYQSALARATADWLVGLNVTRALTVKYQDNLSAGRVQTPTLALVLKQEDKISSFIPQKYYQIALNASNQKALMEQKNPYGIKNREAAQKIVSELERTIGKVEKITVKEHSEKAPLPYDLTELQRAANEKYGYSAKKTLSVVQSLYEVHKIVSYPRTDSKYLSTDMISTMKERLQAVGSMVPEALEYAKKGAKVVQKKVFNNEKVTDHHALVPTEQRPDYAKLSSDEHRIYGMIVKRFVMLFAPEYREQKEKITVSFANRRFNFSKTTVLQKGWKENAQTSGEALHFKEGQQIKGTFEVKEKLTTPPNPLTEGGLLALMERYSLGTPATRAEIIEKLVSSELMERSGNFLRVTRKGRQLLELVNPSLVTPELTEKWEKQLEAIALGKFSSQKFIAEIKDDTKKLVSEVKNSTKKYQDFSMTQKKCPECGAFLKEKKVRDGKLLVCSNAECDYKRRAEARVSNHRCPQCHKKMLIVSGEKGEYFRCKYDGTTEKLGGKKGKKKMSRHEERRLLKKINQDDEPQESALAAALKKAMEEK
(578) DNA topoisomerase 1 [Lactobacillus brevis ATCC 367]
1
MPTKAKPKAKTKTRRKPQKKLVIVESPAKAKTIEKYLGRTYKVVPSLGHVRDLPKSSMGVDTENDYDPHYISIRGKGDVIKGLRSEAKKAKAVYLASDPDREGESIAWHLAHVLNLDVTDKNRVTFNEITKDAVKEAFKTPRSIDMNLVNAQQARRILDRLVGYSISPLLWKKVKKGLSAGRVQSIALSLIIQREKEIKAFIPEEYWTIDGEFKKARHTFAASFYGLNGKKTGLKDNDAVQAVLSKLDKKGNFDITNVVRKERKRTPQPPFTTSSMQQDANRKLNFRTRKTMMAAQQLYEGINLGKEGTQGLITYMRTDSTRISNIAKHEASTFIHEKYGAEYAATKPIKGKLPEGAQDAHEAIRPTSVFRTPASLKERLTKDQFRLYQLIWNRFVASQMTNAIMDTMAVTLEQNGVTFRANGSKMKFEGFLKIYKDGKEKDNLLPDLEIGDQVKLAKTDPAQHFTQPPARYSEANLIKALEENGVGRPSTYAPTLDTIQRRYYVKLVGRRFEPTELGEIVDGIINDYFPDVVNVDFTADLEHELDGIEDGKQDWVKVIDSFYKPFSTEVAHAEDAIEKIQIRDEPAGFDCDIYGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKEIGVTCPVCHKGEVIERKSKKNRIFYGCSRYPDCDFVSWDKPVGRDCPKDGHYLVAKKIRGGSQIVCPNGDYEEAPQK
(466) DNA topoisomerase 1 [Lactobacillus fermentum IFO 3956]
1
MSLATKQESTTKKKTTRRKVSRTNQKKLVIVESPSKAKTIGKYLGRTYKVVASLGHVRDLPKSRMGVDIDHDYQPDYISIRGKGDVIKELRKDAKAAKAVYLASDPDREGEAIAWHVANLLKMDPTEKNRVTFHEITKDAVKEAFKEPRTINMNLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSVALNLIIQRENEIRNFVPEEYWTIDADFKKGREKFQASFYGQNGKKANLKNQEAVQAVLQQLDRQQDFSITKVDRRERRRMPQPPFTTSTMQQDANRRLNFRTRKTMMAAQQLYEGINIGQGAAVGLITYMRTDSTRIAGVAKHEASTFIHEHYGAEYAATKPVKGKLQEGAQDAHEAIRPTSVNRTPAEMKEFLTPDQYKLYNLIWSRFVASQMTPQVTDTMAVTITQNGVDFRANGSKVKFDGFTKVYKGSQGKDNILPNLEEGDAVKMVADNPAQHFTQPPARFTEAALVKTLEENGVGRPSTYAPTLDTIQRRYYVKLESRHFEPTELGEIVNDLITKQFPDIVNVKFTAEVEDSLDKIEEGKENWVQVVDGFYKPFSKEVATAEEQVAKIEMKDELAGSNCEICGAPMVIKMGKYGKFYACSRFPNCRNTKAIVKDTGVECPLCHQGTVVERKSKKNRVFYGCSRYPDCDFLSWDRPIGRDCPKDGHFLVEKKVKGGKQVLCPNGDYKEEVQK
(843) DNA topoisomerase 1 [Lactobacillus sanfranciscensis TMW 1.1304]
1
MVESPAKAKTISKYLGRTYTVVASKGHIRDLPKSRMGIDIPDDFKPDYISIRGKGDTIKMLKAEAKKAKEVFLASDPDREGEAIAWHVSHVLNLDVNDKNRVTFNEITKETVKDALKHPRTIDMNLVDAQQARRIIDRLVGYSISPILWKKVKKGLSAGRVQSVALWIIIKREREIQAFNPEEYWTIDSIFKKGRSKFKASFYGVDGKKFPLGNNDDVQNVLKRLDAKADFEITDVKKREKKRQPPRPFTTSTLQQDANKKLHFKTGRTMMAAQQLYEGINIGKEGSQGLITYMRTDSTRISAGAKLEAAQFIHDEYGPEYALNHPRKLKLPEGAQDAHEAVRPTSVMRTPKQIEKYLTKDQFKLYNLIWSRFVASQMTPAIVDTETIKVVQNGVEYRANGSKLNFEGYLKAYSAGKKKDNILPDLEIGDHITLDNNVPNQHFTQPPARYTEASLIKALEENGVGRPSTYAPTLMTIQKRYYVKLDARRFVPTELGEIVNKLIEEYFPEIVNVDFTADIEGKLDDIEEAKLRWVKLVSEFYQPFSKEVSYAEKEMEDVQIKEPLAGFNCNICGSPMVEKMGKYGKFFACSRFPDCRNTQTIVKEIGVICPKCHEGQVIERKTKKNRLFYGCSRYPDCDFVTWDKPIGRDCPKCGHFLVNKKVRGGWQVICPEGDYEENAIK
(910) DNA topoisomerase 1 [Lactobacillus kefiranofaciens ZW3]
1
MPTKVKSKTKTTKRNTKKRKKTLVIVESPAKAKTIEKYLGRNYHVIASKGHIRDLPKSQMGIDFEDNYKPKYISIRGKGDTIKELKSEAKKAKDVYLASDPDREGEAIAWHVAHALNLDEKAKNRVTFNEVTKDAVKESFKHPRTIDMDTVDAQQARRVLDRIVGYSLSPILWAKVKKGLSAGRVQSVALKLVIDREKEIKNFKPKEYWTIDAEFKKEKESFKSAFYGLNGKKTELANIDAVKDVLAKIDKKKDFTVEKVVSRQRRRQPAAPFTTSTMQQEANKRLGYRTRRTMSIAQQLYEGISLGKQGTVGLITYMRTDSKRTSPVAQKEASQFLHENYGAEFAAKSQRHFQNQEDAQDAHEAIRPTSVYRTPASLKSVLTTEQYRLYKLIWSRFLASEMTPAVYDTVRADIVQNGVIFRTTGSKMRFAGFTKVYDNQQEKNVDLPDLQEGDRVKMSKSDNKQHFTLPPARYTEASLVHALEENGVGRPSTYAPTIDTIQRRYYVKLEGRSIVPTELGEIVDTLIEQFFPDIANVDYTAHLENELDEVEDGQKEWTHVVDEYYQPFKQELNKADSEIEKIQIKDEPAGFNCDICGAPMVIKMGRYGKFYACSRFPDCRNTKPIVKKIGVTCPKCGKGEVVEKKSRRNRKFYGCSRYPECDFVSWDKPIGRNCPNDGHFLVEKKSKKGLTVLCPNGDYREEPQEGESNK
(1669) DNA topoisomerase 1 [Pediococcus pentosaceus ATCC 25745]
1
MPAAKKNLVIVESPSKAKTIEKYLGRTYKVVASLGHIRDLPKSKMGVDLENDYEPHYISIRGKGDTIKNLRKEAKKAKKVYLASDPDREGEAIAWHLSYLLGLDPKDQNRVVFNEITKDAVKNAFKTPRSIDMTLVDAQQARRILDRLVGYSISPLLWQKVKKGLSAGRVQSIALSLIIKREQEIKAFEPEEYWSIDSEFKKGRSKFKAAFYGVNNKKMKLPNNDKVQEVLKKIDPKADFDITEVKRRERKRYPAPAFTTSSMQQEANKTLNFRTRKTMMAAQQLYEGINIGKEGTVGLITYMRTDSTRISEVAKHETSLFIHDEFGAEYAATKPRKGKMPEGAQDAHEAIRPSSVLRTPESIKEYLNKDQFRLYNLIWSRFVASQMTPEVSDTMTVKIEQNGVQFRANGSKTKFEGFTKVYKTNKDKDNVLPNLEEGDQVQLVTNNPNQHFTQPPARYSEATLIKALEENGVGRPSTYAPTLDTIQRRYYVKLESKHFEPTELGEIVNEIIYDFFPDIVNIDFTAGLEKDLDSIEEDKEDWVKVVDRYYKPFAKELAKAQEQIEKVQIKDELAGFNCEICGSPMVVKMGRYGKFFACSRFPDCRNTQAIVKEIGVTCPKCHQGQIIERKSKRGRLFYGCSRYPDCDFVSWDKPIARECPVCHSYLIEKKIKGGKQIVCPNGDYEETPQK
Family distribution
Taxonomy tree
Lactobacillaceae