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Taxon : Rhizobiales
Informations
Name
Rhizobiales
Rank
order
# topoisomerases
57
Lineage and sub-taxa
Lineage
Bacteria
>
Proteobacteria
>
Alphaproteobacteria
>
Rhizobiales
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(170) DNA topoisomerase 1 [Sinorhizobium fredii NGR234]
1
MNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMADPRDIDISLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLQPKAVGNGEEANRLKALLDGASYVVESVEAKPVKRNPGPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDVGGETVGLITYMRTDGVQMAPEAIDAARRAIGSQFGTRYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDEVRRFLDGDMLKLYDLIWKRGIASQMASAEIERTTAEIAADNGGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDESGRLPEINARENLAKQKINATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATISTLVDRDYVEIDKRKLMPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLREFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRTCQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAVSNEPQSLGKDPHTGEEITLRSGRFGPYVQRGDGKDAKRASLPKGWTPATIDHEKALALLSLPRDIGKHPETGKMISTGIGRYGPFVLHDGTYANLESVEDVFSIGLNRAVSALADKQSKGAGGGRTAAAALKELGEHPDGGVMTVRDGRFGPYVNWGKVNATLPKGKDPQSVTVEEALALIAERAAKGGVSKGKAGNGKAARGRSSTAATKSTAAKAEKPKAAAKAKSKTAAKAKKG
(321) DNA topoisomerase 1 [Methylocella silvestris BL2]
1
MYVVIVESPAKAKSINKYLGKGYEVYPSYGHVRDLPAKDGSVDPDADFAMLWDVDVKSAKRLNEIARAVKDADKIILATDPDREGEAISWHVLEVLKAKKVLKDKPVERVVFNAITKSAVLEAMQHPRQIDVALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEAFVAREYWSIVAHLRTQADAPFTARLVGADGKKITRLDVGTGAEAAAFKTDLENATFRVAEIEAKPAKRHPSAPFTTSTLQQEASRKLGFAPARTMQLAQRLYEGADIDGETVGLITYMRTDGVDLAPEAITSARSVIARQFGDAYVPKAPRKYTVKAKNAQEAHEAIRPTDLARLPRAVARALEPDQAKLYELIWTRTIASQMESAELERTTVDIEALAGARKLDLRATGQVVRFDGFLKLYQEGRDDEDDDESARLPDMAKDERLKRERIEADQHFTEPPPRFTEATLVKRMEELGIGRPSTYASTLAVLRERDYVRIEKKRLHPEDKGRLVTAFLEAFFARYVGYDFTADLEEKLDRVSNHEIDWKQVLRDFWLDFSGALAGTKDLRTTEVLDRLNEILGPHIFPPKEDGSDPRGCPSCGEGKLSLKLGKFGAFIGCSNYPECKFTRTLAAPDGAEANGGERPGVKSLGVDPDSGEEITLRDGRFGVYVQQGEGEKPKRSSLPPTIAPADLTLEQAIALLSLPREVARHPESKEPIVAGIGRYGPYVQHGKTYANVAKDEDIISIGANRAIDLIVAKESGLTGRRFGASESAPARVLGEHPAGGAVSVKAGRYGPYVTHGKINATLPKEADPTTLTLEGAVALLAAKASGGGAPMQGRLLGDHPSGGPITVRAGRFGAYVNHGKTNATLKRDASAETITLEEAIRLIEDKEAAGGGPRKAAAPKKAAKSSAAAKKAAPNAKNKTAPANDEDPPFEPSPNRKPAAKAAAAAHKKPAAKAAAAKLKQAKQA
(587) DNA topoisomerase 1 [Brucella microti CCM 4915]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1830) DNA topoisomerase 1 [Brucella suis VBI22]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRITNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRNIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1690) DNA topoisomerase 1 [Brucella melitensis NI]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEILRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYPRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1747) DNA topoisomerase 1 [Candidatus Liberibacter asiaticus str. psy62]
1
MNVIIVESPAKAKTISKYLGSNYKVLSSFGHIRDLPAKKGSVLPEKEFEMIWNIDPSSQKHLQNIIHAVKSSTILILATDPDREGEAISWHVLDVLRQKNLIEKTKIQRVSFNAITKQVVLNAMKSPRDINLDLVNAYLARRALDYLVGFNLSPILWQKLPGARSAGRVQSVALRLICNRENQIESFVSEEYWSLSVLLETPRNDKFTAHLTDFNGQRIEKKSISNKKEADDLISFVKKATYSVEKIENKPIKRNPWPAFTTSTLQQVASSRLGFSASHTMRIAQKLYEGIDVNGEIVGLITYMRTDGVHMSPDALEAVRRSITSHYGDHYLPEKPRIYSSKSKNAQEAHEAIRPNDFDFLPSKMKQFLDSDQFQLYNLIWKRSVASQMASAKFERTTVNIIATYNDQIGHLRTTGSLLCFDGFLKVWENQYDQEKNSEEDILLPYISANEQLIATETNASQHFTEPPPRYSESSLIKKMEEIGIGRPSTYATILETLYKRKYVIAEKRKILPQNTGRIVTAFLENFFSQYVEYDFTADLEEKLDEISTGKLNWKEVLHEFWEEFIEKIDSIKKLRISNVLDILNDTLSSVIFPPKENNEDSRTCPECHTHSLSLKLSSKYGAFVGCTNYPECKYTRQLTSNPQDIPEMKESVLLGNDLETKESVTLRSGRFGLYVQRGDGKDAKRCSLPKTWKSDSVDYDKAMSLLSLPREIGIHPETQKNIIAGTGKYGYYLNHDGAYTKLESIEQVLTIDLEQAISCITEKKKIEKSSRKNSKNQGHVIGTHPEGGSITVHNGRYGPYLHWKKINASLSKEESPDTVDLEKALKILNIKKQKKL
(1624) DNA topoisomerase 1 [Agrobacterium sp. H13-3]
1
MLTDQFQRKNNMNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMSWEVDSASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKRVLGDKPVKRVVFNAITKKAVLDAMANPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVSLRLVCDREAEIERFVSEEYWNISALLKTPRGDEFEAKLVSADGKKLQGRSIKTGDDANRLKALLEGATYIVDTVEAKPVKRNPGPPFTTSTLQQAASSRMGFSASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQMAPEAIDAARRAIGEQFGDRYVPEKARFYSTKAKNAQEAHEAIRPTDFNRTPDQVKRYLDADQLRLYDLIWKRGIASQMASAEIERTTVEILADKDGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDDEGRLPQINARENLAKQKINASQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLKTLSDREYIIIDKRKLIPHSRGRLVTAFLESFFAKYVEYDFTADLEEKLDRISAGELDWKQVLRDFWKDFFAQIEDTKELRVTNVLDALNEVLAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNFTRQLTSDGSEAEASVSNEPKALGADPMTGEELTLRSGRFGPYIQRGDGKEAKRSSLPKGWKPEEIDHEKALALINLPRDIGKHPETGKMISAGLGRYGPFLLHDGSYANLESIEDVFSIGLNRAVTVIAEKQSKGPGRGRNGTPAALKELGDHPDGGPITVRDGRYGAYVNWGKVNATIPKGQDPTSVTLDESLVLIAERIAKTGTGGKPAKAKKPAAKKADGDTAAKPKATKAKAATKSKTAAKPKAAAKPKKAES
(1515) DNA topoisomerase 1 [Agrobacterium fabrum str. C58]
1
MNVVVVESPAKAKTINKYLGSGYKVLASFGHVRDLPAKDGSVLPDQDFEMSWEVDSASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKRVLGDKPVKRVVFNAITKKAVLDAMANPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFVSEEYWNISALLKTPRGDEFEAKLVSADGKRLQSRGIKTGEDANRLKALLEGATYVVDTVEAKPVKRNPGPPFTTSTLQQAASSRMGFGASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQIAPEAIDAARLAIGEQFGERYVPEKARFYSTKAKNAQEAHEAIRPTDFTRTPDQVKRYLDADQLRLYDLIWKRGIASQMASAEIERTTVEILADKNGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDDEGRLPQINARENLAKQKINASQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLKTLSDREYIVIDKRKLIPHSRGRLVTAFLESFFTKYVEYDFTAALEEKLDRISAGELDWKQVLRDFWKDFFAQIEDTKELRVTNVLDALNEVLAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNYTRQLTSDGAEADAAASNEPKALGADPMTGEELTLRSGRFGPYIQRGDGKEAKRSSLPKGWKPEDIDHEKALALINLPRDIGKHPETGKMISAGLGRYGPFLLHDGSYANLESIEDVFSIGLNRAVTVIAEKQAKGPGRSGTPAALKELGDHPDGGAITVRDGRYGAYVNWGKVNATIPKGQDPASVTLDESLVLIAERIAKTGTGGKPAKAKKTTAKKADGEAAAKPKATKAKAATKSKAAAKPKAAAKTKKAAE
(1503) DNA topoisomerase 1 [Agrobacterium vitis S4]
1
MNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDTASAKRMKDIADAMKGADALFLATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMAAPRDIDGDLVDAYLARRAMDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRENEIERFVSEEYWNLSALLKTPRGDEFLARLVSADGKRLQARSVGNGDMANRLKDLLDGANYVVESIEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARSAITQQFGPRYMPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRYLDADQLRLYDLVWKRGIASQMASAEIERTTAEILADKAGEKAGLRAVGSVIRFDGFIAAYTDHREEGEKSDDDDEDGRLPEINAREALAKQKVNATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATLKTLSDREYVVIDKRKLIPEAKGRLVTAFLESFFTRYVEYDFTADLEEKLDKISAGELNWKDVLREFWQNFFAQIEGTKELRVTNVLDALNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNFTRQLSADGGTEAEAVGNEPKALGEDPTTGEQITLRSGRFGPYVQRGDGKEAKRSSLPKGWSPTDVDFDKALSLLSLPREVGLHPETGKMMTAGLGRYGPFVLHDGTYANLDGIEDVLTIGLNRAVTVLAEKQANPGGRGRAAPAALKEIGDHPDGGAITVRDGRYGPYVNWGKINATIPKGMDPQAVTMEEAIALIVERAAKEGSGKTKAKPAAKSASAKKAPAKKPAAKATKADADDAADAKPKKAAAKPKATKPKAKPAAKTEKA
(994) DNA topoisomerase 1 [Sinorhizobium fredii HH103]
1
MTMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLKKKKVIGDKPVKRVVFNAITKKAVLDAMADPRDIDISLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNIVALLKTPRGDEFEARLVSADGKRLQPKSIGNGEDANRLKALLDGASYVVESVEAKPVKRNPGPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDVGGETVGLITYMRTDGVQMAPEAIDAARRAIGSQFGPRYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRVLDGDMLKLYDLIWKRGIASQMASAEIERTTAEIAADNGGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINATQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATISTLVDRDYVEIDKRKLMPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLREFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRTCQVCGTGKLSLKLGKYGAFVGCSNYPDCNYTRQLSSDSNGDAEAAVSNEPQSLGKDPHTGEEITLRSGRFGPYVQRGDGKDAKRASLPKGWTPATIDHEKAIALLSLPRDIGKHPETGKMISTGIGRYGPFVLHDGTYANLESVEDVFSIGLNRAVSALADKQSKGAGGARGRTAAAALKELGEHPDGGAMTVRDGRFGPYVNWGKVNATLPKGKDPQSVTVEEALALIAERAAKGGVSKGKSAKGRSAATKSTAAKAEKPKAAAKAKSKTAAKAKKG
(389) DNA topoisomerase 1 [Sinorhizobium meliloti AK83]
1
MNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLRKKKVIGDKPVKRVVFNAITKKAVLDAMAEPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPPKAIGNGEEANRLKSLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFDRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLVPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAAANEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPAAIDHEKALALLSLPRDIGPHPESGKMISTGIGRYGPFVLHNGTYANLESVEDVFSIGLNRAISVLADKQSKGAGGGRASAAALKELGEHPDGGAITVRDGRFGPYVNWGKVNATLPRGKDPQSVTVEEALALIAEREAKGGVTKGKAAKGKPTGGKSAGTKSAKAASAGTAKAEKPKSAAKTKTKAAAKAKKD
(623) DNA topoisomerase 1 [Sinorhizobium medicae WSM419]
1
MSWRRYWRAWSPKQLFQRMSMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKASDGLILATDPDREGEAISWHVLDLLRKKKVLGDKPVKRVVFNAITKKAVLDAMAQPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPAKAIGNGEEANRLKTLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGIDIGGETVGLITYMRTDGVQMAPEAIDAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFNRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKRAGLRATGSVIRFDGFIAAYTDMKEDGEQTDDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLLPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDRISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSSGDAEAAASNEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPATIDHEKALALLSLPRDLGPHPETGKMISAGIGRYGPFVLHNGTYANLESVEDVFSIGLNRATSVLADKQSKGAGGAGGRTGAAAVKELGEHPDGGAITVRDGRYGPYVNWGKVNATLPRGKDPQSVTVEEALAFIAERAAKGGVTKGKTAKGKSAGRKQAGTKTAKAAGTATAEKPKRAAKTKTKSAAKAKKD
(1205) DNA topoisomerase 1 [Ochrobactrum anthropi ATCC 49188]
1
MNVVVVESPAKAKTINKYLGSNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSSKRLADIVKALKDSDGIILATDPDREGEAISWHVLEVLNQKKALKGKTVKRVAFNAITKKAVLDAIANPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVADRESEIERFIREEYWNIAALLKTPRNDGFTARLTAVDGKKLGKLDIKNGEQATAIRTMLEGASFKALSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIGKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRYLDDDQARLYELIWKRAIASQMQAADIERTTVDIEAVNSSRSAMLRANGSVTKFDGFLAAYMDHREEEDDDEDSAKLPEIRSGEALAREKIDATQHSTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDREYITIDKRKLIPEPKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKDVLRDFWRDFSGNVDDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGMLSLKLGKYGAFVGCSNYPECKYTRQLGGDANGESAAADEPKSLGKDPFTGEEITARTGRFGPYVQRGEGKEAKRASLPKGWTVDTLDHEKAVALLSLPRDIGQHPETGKMISAGIGRYGPYVSHDGTFANLENAEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGSITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKSKKTPARKASASTEKKAAAKKPAAKKAPAKAKSTAKPKAKSKAETVEE
(1623) DNA topoisomerase 1 [Rhodopseudomonas palustris CGA009]
1
MNLVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDADFQMIWEVDPKAASRLNDIAKALKGADKLILATDPDREGEAISWHVLEVMKQKRALKDQQVERVVFNAITKQSVTDAMKHPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRETEIEKFVPREYWSLIATMATPRGETFEARLVGADGKKIQRLDIGTGAEAEDFKKAIEAANFRVATVEAKPARRNPYAPFTTSTLQQEASRKLGFAPAHTMRVAQRLYEGVDIGGETVGLITYMRTDGVQIDSSAITQARKVIAEDFGNAYVPDAPRQYTAKAKNAQEAHEAIRPTDLSRRPSDVSRNLDSDQARLYELIWIRTVASQMESAELERTTVDIEAKAGSRVLELRATGQVVKFDGFLAAYQEGRDDDSEDEDSRRLPAMSENEALKREALAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVRLEKKRLHGEDKGRVVVAFLESFFTRYVEYDFTAGLEEDLDRISNNEVSWKQVLSDFWRDFIGAVDEIKDLRVAQVLDVLDEMLGPHIYPAREDGGDPRQCPSCGTGKLNLKAGKFGAFVGCSNYPECRYTRPLASDSAGDADRVLGTDPDSGLEVAVKSGRFGPYIQLGEAKDYAEGEKPKRAGIPKGTSPSDVDLEMALKLLALPREVGKHPETGQPIKAGIGRFGPYVQHEKTYASLEAGDDVHTIGLNRAVTLIAEKVAKGPSKGRFGSDPGKALGDHPSLGAVAVKKGRYGAYVTAGGVNATIPNDKTEDTITLPEAIALLDERAAKGGGKAKKAPAKKAAAKKASADGEAKPVKKAAAKKAKPKAEGAAASKARAPVAAKTAAKKAAKPKDAAKSSAAKNG
(1366) DNA topoisomerase 1 [Oligotropha carboxidovorans OM4]
1
MNLVIVESPAKAKTINKYLGSSYEVLASYGHVRDLPAKNGSVDPDANFQMIWETDPKAASRLNDIAKALKGADKLILATDPDREGEAISWHVLEVMKQKRALKDQKVERVVFNAITKQSVTEAMNNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREIEIEKFVAREYWSLVATLATPRNDTFEARLVGADGKKIQRLDIGTGAEAEDFKKALETAAFTVSLVEAKPARRNPQAPFTTSTLQQEASRKLGFAPSHTMRIAQRLYEGIDIGGETTGLITYMRTDGVSIAPEAIPALRKVIAEEYGSNYVPSAPRQYTSKAKNAQEAHEAIRPTDVSRRPAKLKARLDNDQYRLYELIWMRAIASQMESAELERTTVDITAKAGARTLELRASGQVVKFDGFLAVYQEGRDDDPEDEESRRLPAMSEGEALKRESLAVTQHFTEPPPRYSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLSAEDKGRVVVAFLQKFFARYVEFDFTADLEEQLDKISNNEVAWKNVLSDFWRDFIGAVDEIKDVKVSEVLDVLDAMLGEHIYEPRADGGDPRQCPSCGTGRLNLKAGKFGAFVGCSNYPECRYTRPLAASSGTSDRVLGKDPKTNLDVAVKAGRFGPYIQLGEPNDYAEGEKPKRAGIPKNMSPADVELDLAIKLLSLPRDVGPHPEDGEIITAGIGRFGPFVRHGKTYASLEAGDDVYTIGLNRAVTLIAEKIAKGPSRRFGADPGKEVGDYPARGGKIMLKKGRYGAYVTIDGINATIPDDKEPDQITLEEAIALIEARAAKGGKAKRAPKKAAAKKAAPKKKATAKKKADSEPESGAKPAKKAATRTAPKARTSTAKPAAKTAAKAKPTAKKSAGKARG
(184) DNA topoisomerase 1 [Hyphomicrobium sp. MC1]
1
MNVVIVESAAKAKTINKYLGSGYKVIASYGHVRDLPAKDGSVEPDHDFNMHWEVDTKSQKIMREIAEAVKKADKLILATDPDREGEAISWHILQILNQKKALGKDTEVERVAFNAITKQSILAALKEPRKIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLVCDREAEIEAFKTEEYWTIEALLSTAKNEDVRSRLVAIDGTALKKLDIKDEATATAIRKALLGQDFRIASVEKKATKRNPFPPFTTSTLQMDASRKLGFSAKQTMQIAQRLYEGVDIGGETVGLITYMRTDGVQIVPEAVSQIRDVISAEYGKNYTPFAREYKTKAKNAQEAHEAIRPTDPRRKPDQVRKHLEKDQAALYDLIWKRTIASQMAAADIEQTTAEIDVKGSDGKAYGLRANGSVLMFDGFLKVYEEGRDDRVRTIEKGKDDTADEDDDSRRLPPLAVGDRLKDKEISADQHFTQPPPRFSEATLVKRMEELGIGRPSTYASTMAVLVDRDYVRIEKKRLIPEDKGRLVIAFLESFFKRYVEYDFTADLEEKLDLISNDELEYKQVLRDFWRDFMAAVGEIKDLRVGDVLEALNEMLGPHVFPDKGDGSDPRLCPKCGTGRLSLKISGKYGAFIGCGNYPECNYTRQLTQSSDGDAAALDGKILGYNDDGLAVTMKTGRFGPYIQLGEAEGDEKPKRSSIPRGIDAATLDFERAMQLLSLPRDVGEHPDEGGMITAGLGRFGPFIVHEKDGAKTYVNLESLEDVFTVGLNRAVTLIAEKRAGGGKSRFQRNAPKVVKDLGQHPSEGGAVQVLEGRYGPYVTHNKVNATVPKAKNPAELTMDEAVALINERTANGGGKKGKPARGAKAKAAKDDKPAKAPKADKAAAPKAAKKPAATKTAAAKAEKAPAKKAPATSAGAKKLARAKA
(396) DNA topoisomerase 1 [Hyphomicrobium denitrificans ATCC 51888]
1
MNVVIVESAAKAKTINKYLGSGYKVIASYGHVRDLPAKDGSVEPDHDFAMQWEVDSKSQKIMREIADALKNADKLILATDPDREGEAISWHILEILNNKKALKKGTEVERVAFNAITKQSILAALKEPRKIDEPLVEAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFKTDEYWTIEALLTTSRGDDVKTRLVAIEGTALKKLDIKDEASATAIKAALEGRDFRVASIEKKAAKRNPYPPFTTSTLQMDASRKLGFSAKQTMQIAQRLYEGVDIGGETVGLITYMRTDGVQIVPEAVSQIRDVISAEYGKQYTPFAREYKTKAKNAQEAHEAIRPTDPRRKPDQVRKYLEKDQAALYDLIWKRAIASQMAPADMEQTAVEIEAKGSDGKNYGLRANGSVLLFDGFLKVYEEGRDDRFRYIEKGKDDPEGEDEDRRLPALAEGDHLKDKEISADQHFTQPPPRFSEATLVKRMEELGIGRPSTYASTMAVLVDRDYVRIEKKRLVPEDKGRLVIAFLESFFKRYVEYDFTAELEEKLDLISNNELAYKEVLRDFWRQFIASVGEIKDLRVGDVLEALNEMLGPHVFPDKGDGSDPRLCPKCNQGRLSLKISGKYGAFIGCGNYPECNYTRQLSQSANNGEAALDGKVLGYNDDGIAVALRTGRFGPYIQLGEATGDEKPKRSSIPKGIDAATLDFEKAMQLLSLPRDVGVHPTEGGMITASLGRFGPFILHEHDGAKTYVNLGNVEDVFTIGINHAVTLLAEKRAGGGKSRFQRNAPKVLKDLGAHPSEGGPVQVLEGRYGPYVTHNKVNATVPRGKDPSALTMDEAVALIAERIANGGGKKSKASRSSAKPKAAKAAKPAKGEAAPAAKRTAKPAAAKKAAPAKKSAAKPAAKKLAKAKA
(1146) DNA topoisomerase 1 [Rhodomicrobium vannielii ATCC 17100]
1
MNIVIVESAAKAKTINKYLGADYKVIASYGHVRDLPAKDGSVLPDNDFEMTWEVEADSNRIVNEIAKAVKGADRLILATDPDREGEAISWHLLKILEQKRALNGVSVERVAFNAVTKDAILTAMKNPRKIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVVDREAEIEAFRTREYWTVEAALKNGGGDAFTARLVARAGKKLDKFDIPNEALAHAYRDAIKGQSYRVDSVDAKDHKRNPAPPFTTSSLQQEASRKLGLSPRQTMQIAQKLYEGIDIGGETVGLITYMRTDGVQIVGEAIAQARGQIESQFGARYVPSAPRIYKTKAKNAQEAHEAIRPTDFGRQPDKLRGLSAEEARLYKLIWQRAVASQMASADIERTTAEISVPGKDGVPYGVRATGSVVKFDGFMRLYEEGRDDTDDEDSARLPPLKQGEALKDSGVTAAQHFTEPPPRYTEATLIREMERLGIGRPSTYASTMAVLREREYVKLEKKRLVPEDKGRLVTTFLEAFFKRYVEYDFTAYLEDRLDQISDGKLDWKALLREFWQDFIGAVTDIKDLRVTQVLDALNELLGPHIFPAKEDGGDPRLCPLCNQGQLSLKIGKFGAFVGCSNYPECRYTRQLKTGENGNGDGAAPAGDTVLGNDPETGLAVCLKNGRFGPYIQLGEGGDGEKPKRASIPGGMGLADVDFAYALKLLALPREVGPHPETQKTIMAGFGRYGPYVEHDGKYVKIDAEEVFTIGLNRAVTVIAEGGTGGKGRAPKTEPIKVLGEHPEKGGKMEVLAGRFGPYIKWGKVNATIPKGTEPQDVTVDEAVRLIAARIEAGDGKKGRGKPTKSAKAPAKEKKPAKAKTADAGDEAEAPKKAKTAAPKKAAANGKAKSSAKEKSAKADEADKKPKAKASAKKTTSKAAGGTT
(1538) DNA topoisomerase 1 [Pelagibacterium halotolerans B2]
1
MKVVIVESPAKAKTINKYLGKDFEVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDTNSKKRLADITRALKGADELILATDPDREGEAISWHLLDALKAKKAIKADMPVKRVVFNAITKDAVTTAMQHPRDIDAPLVDAYLARRALDYLVGFTLSPILWRKLPGSRSAGRVQSVALRLVTEREEEIERFKPQEYWSVIPTLNQTGKSFATRLYSVDGDKTDKLAIKTGEDAQGLKTAIEKGNFKVASVDRKPTKRNPYAPFTTSTLQQDASSRLSLSPSRTMQIAQRLYEDGLITYMRTDAVQMAPEAIEAARRVIGKEFGSEYVPEKPRFYSTKAKNAQEAHEAIRPTDLGKHPDTLRNLDPDQHKIYQLIWRRALASQMRSAEIERTTADIDVLAAGRAITLRATGSVVTFPGFLGVYGVEKTDEDDEDGKDLPALNVGDTPALENVAIEQHFTQPPARYTEASLIKKMEELGIGRPSTYAATLKTLQDRDYIKLEKRAIMPEDRGRLVTAFLQSFFTKYVEYGFTAGLEEELDEISAGEIDYKEVLRRFWKDFSHQADEIKDLRVSEVLDALNDLLGHHIFPERPDGTDPRLCPTCGTGQLSLKLGKYGAFIGCSNYPECRHTQQLAESATGQASEAAQGDGVLGADPETGAEIYLKTGRFGPYVQLGEDAKDAKRSSIPKGWDAGSMDLEKALKLLSLPREVGLHPEDGKPISAGIGRYGPFVLHEKTYANLPDVEEVFTVGLNRAVDLIAQKRAGGGRGGRGAAVAAIQTFEHDDGPITVRAGRYGPYVNQGKVNATLPKDLAPEAVTLEKALELIAAKGGSKSKAKAKPKPAAKKPAAKKTATKKPAAKKKAEA
(503) DNA topoisomerase 1 [Mesorhizobium ciceri biovar biserrulae WSM1271]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHIRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAALLGTPRNENFEARLTAFDRKKLQKLDISNKAQADDIKSMLEGATFKAVSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSASRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRQYTAKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAIASQMQPAEIERTTAEIEAVNGSRTAELRAIGSVVRFDGFIAAYTDQKDDDAEDEENRRLPEIRAGEQLARQAINATQHTTEPPPRYSEASLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFKRYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGEDGTKVIGKDPYTSEEITLRSGRFGPYLQRGDGKEAKRSSLPKGWTAESIDHEKALALLSLPRDVGQHPETAKMISAGLGRYGPFVLHDGTYANLESIEDVFSIGLNRAVSVIAEKQLKGKGGRNGGTAAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTMEDALALIAEKEAKGGGGKKPFRKAAAAKAPATKKVAAKKPAAKKPAAKKKG
(662) DNA topoisomerase 1 [Mesorhizobium opportunistum WSM2075]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAAILGTPRNEAFEARLTAFERKKLQKLDISNKAQADDVKAMLEGAAFKALSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSATRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRVYTTKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAISSQMQPAEIERTTVEIEAVNGSRTAELRAVGSVVRFDGFIAAYTDQKEDDAEDEENRRLPEIRVGEQLARQAINATQHTTEPPPRYSEATLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFERYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGEDGTKVLGKDPYTAEEITLRSGRFGPYIQRGDGKEAKRSSLPKGWTPESIDHEKALALLSLPRDVGKHPESGKMISAGLGRYGPFVLHDGTYANVDSIEDVFSIGLNRAVTVIAEKQSKAKGGRNGGTAAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTIEDALALIAEREAKGGGGKKPFRKAASPATKKAATKKPAAKKKG
(47) DNA topoisomerase 1 [Chelativorans sp. BNC1]
1
MDVVVVESPAKAKTINKYLGKDYKVLASFGHVRDLPAKDGSVRPEEDFAMSWEVDSPSAKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLRQKRALKDKPVRRVVFNAITKKAILDAMASPREVDASLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDLEAEIERFVREDYWQIAALLDTPRGDSFEARLTTLDGKRLQKLDIKSQEEADSIKALLDGAAYRVLSVEAKPTRRNPGPPFTTSTLQQAASSRLSFSASRTMQVAQRLYEGVEIGGETTGLITYMRTDGVQMAPEAIEAARSAVSNTFGPRYLPEKPRHYSSKAKNAQEAHEAIRPTDFSRTPDEVRKYLDSDQARLYEMIWKRAIASQMEAAEIERTTVEIEASGAGRAAGLRAVGSVVRFDGFLAAYAEVKDEDSQDEEDRRLPEINSGEALKRNSVNVTKHTTEPPPRYSEASLIKKLEELGIGRPSTYAAILKTLDDRGYVSNERRKLVPQAKGRIVTAFLENFFRRYVEYDFTADLEEKLDEISDGKLSWKQVLRDFWKDFSAAVGDIKELRVTDVLDALNEELAPLVFPTREDGGDPRICPKCGAGKLSLKLGRYGAFVGCSNYPECDYTRQLGENPAENGEAEAGLNGNKVLGTDPFTGEEITLRSGRFGPYVQRGEGKDAKRAGLPKGWTPEDLDHEKAIALLSLPRDVGKHPETGKMISAGIGRYGPFLLHDGTYANLETVEDVFSVGLNRAVSLLAEKQAKTNGARAKPAALKELGEHPDGGVITVRDGRFGPYVNVGKVNATLPKGKDPMSLTREEALELLAAKAGKTGKKPAKSKARS
(1004) DNA topoisomerase 1 [Azorhizobium caulinodans ORS 571]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATDPDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTAAFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATRNAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTADIIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRDFWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSGGEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPEDGEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFGPYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKKTAKAKADAAAEE
(183) DNA topoisomerase 1 [Starkeya novella DSM 506]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHVRDLPAKDGSVDPEHDFHMLWDIDPKAQKRLSDIARAVKGADGLILATDPDREGEAISWHVLEILKEKRALKDQPISRVVFNAITKQAVLDAMAHPRTIDAALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIETFVKREYWSIAATLATPRNETFEARLVGADGKKITRLDVGTEAEATDFRKALESADFKVRSVEAKPARRHPYPPFTTSTLQQEASRKLGLAPAVTMRIAQRLYEGVDVGGETVGLITYMRTDGVDMAPEAVAQARSVIGRDYGDRYVPNAPRKYTAKAKNAQEAHEAVRPTDLSRRPKDVSRHLEPEQAKLYELIWLRTVASQMESAELERTTVDIDAKAAGRALELRATGQVVKFDGFLTLYREGIDDGDEDEENRRLPAMSTGEALANKGIKADQHFTEPPPRYSEASLVKRMEELGIGRPSTYASVLAVLRDREYVKLDKRRLVPEDKGRLVTAFLESFFDRYVEYDFTADLEEKLDLISNGELAWKDVLRDFWRDFTAAVGETKELRVSDVISALDEMLTAHIFPPKEDGSDPRICPTCGTGRLSLKVGKFGAFIGCSNYPECKYTRPLAVQNGDSDNPAEANGTRVLGTDPVSGLEVTVRDGRFGAYLQLGEAKDGEKPKRSSLPKGLAPADVDLETGLALLSLPREIGVHPDNGEPILAGIGRFGPYVQHGRTYANLEAGDDVLSIGLNRAVALIADKQNKGPGRGRGAVGGRELGEHPTLGGQVTVRPGRFGAYVNHGKVNATLPKSMPAESVTLEQAVELITAKAGSAPAKPARRAAAKTASGDKPAKKAAPKKAAAKKSPAKKSG
(1057) DNA topoisomerase 1 [Candidatus Liberibacter solanacearum CLso-ZC1]
1
MNVIIVESPAKAKTISKYLGPDYKVLSSFGHVRDLPAKKGSVLPEKNFEMLWETDKSSQKHLENIISAVKSSTLLILATDPDREGEAISWHVLDILRQRNLIGERKIKRVSFNAITKKVVLNAMENTRDLNLDLVNAYLARRALDYLVGFNLSPILWRKLPGARSAGRVQSVALRLICHRENQIECFVSEEYWLLSVLLETPRGDKFIARLVDFNGQRIEKTSIGNKKEADKLISFLEKATYIVKNTETKPIKRNPWPAFTTSTLQQAASSRLGFSPSYTMRIAQKLYEGIDVNGEVVGLITYMRTDSVHLSLDALEEVRRSISSNFGNSYLPDKPRIYSVKAKNAQEAHEAIRPNDFNFLPSEMKKFLDSDQFQLYNLIWKRSVASQMASAEFERTTISIDATYEDQIAHLRTVGSCLRFDGFLKVWENQNDQENNSDEDKLLPCINKNEKLLAKETNASQHFTEAPLRYSESSLIKKMEELGIGRPSTYAAILETLSKRRYIVIEKRKLFPQNTGRIVTAFLENFFSRYVEYDFTADLEEKLDKISSGKLDWKEVLHEFWKEFIEKIDSTKELRTSNVLDILNDTLSSVIFPAKDNNEDSRTCPSCQKNPLSIKLSSKYGAFVGCTNYPECKYTRQLTTSNQQYIEENLEPLLLGDDPETKEPITLRSGRFGFYVQRGDGKDAKRCGLPKNWDRESIDYDKALSLISLPREIGIHPETQKSIIASMGKYGCYLKHDGHHTKLESIEQVLTINLDQAISCMIQKNKKEKSSRTSTKNQGHVIGIHPEGGSITIHRGRYGPYLNWGKINASIPNNENPDTIDLENALKIFETKIKGKKKS
(1309) DNA topoisomerase 1 [Bartonella clarridgeiae 73]
1
MNIVIVESPAKAKTINKYLGSQYKVIASFGHVRDLSAKDGSVLPDKDFAMKWDIDTASAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDILKQKKVLNNKPIKRVVFNAITKKSVLAAMKNPRDIDISLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICNRESEIEQFIKEDYWSITTYLKTLQDNIFYARLTEFNHKKLGKLDIRSQEQADQIFFMLEKANYRTLSIEAKPIKKNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVEINGETAGLITYMRTDGVQMASEAIDAARKAIIDSFGNHYVPEKPRFYSTKAKNAQEAHEAIRPTDFKRHPNQICNVLDSDQAKLYELIWKRAIASQMRSAEIERTTVEIEAFQEENHANLRAIGSVIHFDGFISAYTDPKEEENSEEDESTRLPQINIGESLKKEKVELTQHTTEPPPRYSESALIKKLEELGIGRPSTYASTLSTLCDRGYIITDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTANLEEKLDLISDGKLSWKDVLHDFWDEFNASITSIQELRIMNVLDVLNVTLAPLAFPTREDGSDCRSCPLCINGQLSLKLGRYGAFVGCSNYPECKYTCQLGTDTKEKSKVVHNDEPIMLGIDPETGKDISLRNGRFGPYIQLGEDKKSKRASLPKGWQIENINFDKALALLSLPREVGTHPETGKIITAAIGRYGPYLAHDGKYANLFSIDEVFDIGINRAITILAEKKNNETNRRRILPTVLTTLGDHPEGGTITIRDGRYGPYVNWNKINATLPRDKDPTTVTLSEALELISAKASTKKTGQKATSKKKLTPKKASPRKEKA
(494) DNA topoisomerase 1 [Bartonella bacilliformis KC583]
1
MDIVIVESPAKAKTINKYLGSQYKVIASFGHVRDLSAKDGSVLPDKDFSMKWDVDTASAKRLNEIAKAVKEANSLILATDPDREGEAISWHILDVLNQKKILNDKPVKRVVFNAITKQSVLDAMNNPRDIDVSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEREHFVKEDYWSITTYLKTPRNDVFQARLIEFNQKKLSKLDIQSQEQANQIRLMLEEAEYCTLSVEAKPTKRNPSPPFTTSTLQQASSSKLGFSASRTMQIAQKLYEGVEMNGETAGLITYMRTDGVQIAPEAIDSARRAISNSFGNNYLPEKPRFYSTKAKNAQEAHEAIRPTDFKRHPDQVRNFLDNDQAKLYELIWKRAIASQMRSAEIERTTVEIKAVQEENYANLRATGSVTRFDGFIAVYTDQRDETNGDEDDLARLPPINVNEILTKEKIETAQHTTDPPPRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIIIDKRQLTPDAKGRIVTAFLENFFNRYVEYGFTANLEEKLDLISDGKLFWKDVLRDFWDEFNASVTNIQELRITNVLDVLNTTLAPLAFPTREDSSDPRSCSLCKHGQLSLKLGRYGAFVGCSNYPECKYTKQLGTDAGEEREAAHNDEPVILGVDPETGKDIFLRNGRFGPYIQLGEGKEAKRSGLPKGWKTENVNLDKALSLLSLPREVGIHPETGQMITATIGRYGPYLTHDRKYAALSNVDDVFDIGINRAVTVLAEQKENKANRGKTVSSVLAALGDHPDGGSITVRDGRYGSYVNWGKINATLPKDKDPANITLSEALELLSAKTSAPSKTRKVAAKKTAPKKNTTVKKASSTIKKAK
(38) DNA topoisomerase 1 [Bartonella tribocorum CIP 105476]
1
MNIVIVESPAKAKTINKYLGPQYKVVASFGHVRDLPAKDGSVLPDQDFSMKWDIDSAAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPIKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTQLKTIRNDHFQARLTMFNQRKIGKLDIQSQEQADQIRLMLEKAQYHTLSVEAKPTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGEVAGLITYMRTDGVQIAPEAIDAARKVIHESFGKDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRSPNQVRNFLDDDQAKLYELIWKRAIASQMCSAEIERTTVEIEAQQGDNRANLRATGSVVRFDGFISVYTDQRDEENNEENETTRLPQINTGEALTKEKVESLQHTTEPPSRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIVIDKRKLIPDAKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNTSISNIQELRIANVLDVLNVTLAPLAFPEREDGSDVRSCPLCKNGQLSLKLGRYGAFVGCSNYPECRYTRQLGTTDTEEENEAVRNDEPVMLGIDPETGKDISLRNGRFGPYIQRGESKEVKRAGLPKEWQAENITLERALALLSLPREIGIHPETGKMITATIGRYGPYLSHNGKSARLLHADEVFDIGINRAVTVLAEQQENKTKQSRTTSAALATLGEHPEGGTVTVRNGRYGPYVNWGKINATLPKEKDPISVTLSEALELISAKASSKKAISKRASSKTKAKTKET
(155) DNA topoisomerase 1 [Bartonella quintana str. Toulouse]
1
MNIVIVESPAKAKTINKYLGSQYKVLASFGHVRDLPAKDGSVLPDQDFSMKWDVDSAASKRLNEIAKAVKEADSLILATDPDREGEAISWHILDILRQKKVLKDKPVKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTDLKTIRNEGFQARLTMFNHKKIGKLDIQSQEQADQMRHMLESAKYHTLSVEAKHTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGVEINGEMAGLITYMRTDGVQIAPEAIDSARKVIHEFFGSDYVPEKPRFYSTKAKNTQEAHEAIRPTDFQRIPNQVRNFLDTDQVKLYELIWKRAIASQMRSAEIERTTVEIEAQQGENHANLRATGSVIRFDGFISVYTDQRDEENSEENEITHLPQINTGETLTKEKVEAIQHSTEPPPRYSEASLIKKLEELGIGRPSTYASTLATLSDRGYIIIDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRNFWDGFNASITNIQELRITNVLDVLNITLAPLIFPGREDGNNVRSCPLCSSGQLSLKLGRYGAFVGCSNYPECKYTRQLGTDPGEEKEVMRNDEPVMLGIDPKTGKDVSLRNGRFGPYIQVGEQKEAKRVRLPKEWQTEKMTLDKALALISLPREIGIHPETGKIITATIGRYGPYLAHDGKYAPLLHADEIFDIGINRAVTVLAEKQENKTKRNRTKTAALATLGDHPDGGTVTIRNGRYGPYVNWGKINATLPKDKDPISVKLSEALELISDKASSKKTTAKKASSKRKET
(23) DNA topoisomerase 1 [Bradyrhizobium japonicum USDA 6]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDANFKMIWEVDPKAAGRLNDIAKSLKGADRLILATDPDREGEAISWHVLEVLKEKRALKDQKIERVVFNAITKQAVTDAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLIATLLTPRGDAFEARLVGADGKKIQRLDVGSGAEAEDFKKALEAAAYAVTAVDAKPARRNPQAPFTTSTLQQEASRKYGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDPSAITQARKVIGEDYGNAYVPEAPRQYQAKAKNAQEAHEAIRPTDMSRRPDSMSRKLDADQARLYELIWKRTIASQMESAELERTTVDITAKAGSRTLELRATGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSPNDALKRQSLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLHGEDKGRVVVAFLESFFNRYVEYDFTANLEEQLDRISNNEISWQQVLKDFWTGFIGAVDEIKDLRVAQVLDVLDDMLGQHIYPPRADGGDIRQCPSCGNGRLNLKAGKFGAFVGCSNYPECRYTRQLAADSETTADRSLGQDPDTGRDVWVKAGRFGPYIQLGEPKDYEEGEKPKRAGIPKGTSPGDVELELALKLLSLPREIGKHPETGQPITAGLGRFGPFVKHEKTYASLESGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKAIGDHPTLGTVTVKSGRYGAYVTAGGVNATIPAEFEKDTVTLPQAIALIDERAAKGGGKTKAKKAAKPAKAKKAAEKAADGDDAAPKPKKPAAKKAAKPKSESTSKARAAVSSTAKTSPTKAAAPKAPAKKSAGKT
(942) DNA topoisomerase 1 [Bradyrhizobium sp. ORS 278]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPEENFRMIWEVDPKAAGRLNDIAKSLKGADRLILATDPDREGEAISWHVLEVMKEKRALKDQKIERVVFNAITKQAVSEAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLIATLATPRGDTFEARLVGADGKKIQRLDIGTGAEAEDFKNALNAATYSVATVDAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIAPEAITQARKVIGEIYGNKYVPDSPRQYQTKAKNAQEAHEAIRPTDLSRKPAELRKRLDDDQAKLYELIWTRTIASQMESAELERTTVDIVAKAGGRTLELRATGQVIKFDGFLALYQEGRDDEEDEDSRRLPQMSQGEALKRQNLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILDVLKARGYVKLEKKRLHGEDKGRVVIAFLENFFRRYVEYDFTADLEEQLDRISNNEIAWQQVLKDFWTGFIGAVDDIKDLRVAQVLDALDEMLGPHIYPPREDGGDVRQCPTCGTGRLNLKAGKFGAFVGCSNYPECRYTRPLAADSEAAADRMLGQDPDSGLEVAVKAGRFGPYIQLGEQKDYAEGEKPKRAGIPKGTQPSDVDLDLALKLLSLPREIGKHPETGLPITAGLGRFGPFVKHDKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSKRFGADPGKALGDHPSLGPVAVKAGRYGAYVTAGGVNATIPGDKEKDTITLAEAIALIDERAAKGGGKAKAPKKAAKPKAAAKPKAGGDDDTPKPAKKAVAKKAAAKPKSDSTSKARAPVAKAAKTSAKPATKATPKKSAGKARG
(1368) DNA topoisomerase 1 [Bradyrhizobium diazoefficiens USDA 110]
1
MNIVIVESPAKAKTINKYLGSSYEVLASFGHVRDLPAKNGSVDPDANFKMIWEVDPKAAGRLNDIAKSLKNADRLILATDPDREGEAISWHVLEVLKEKRALKDQKIERVVFNAITKQAVTDAMKHPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVAREYWSLVATLLTPRGDAFEARLVGADGKKIQRLDIGTGAEAENFKKALEAAAYAVTAVDAKPARRNPQAPFTTSTLQQEASRKYGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDPSAITQARKVIGEDYGNAYVPEAPRQYQAKAKNAQEAHEAIRPTDMSRRPDSMSRKLDSDQARLYELIWKRTIASQMEAAELERTTVDITAKAGGRTLELRATGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSAGDGLKRQSLAVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLHGEDKGRVVVAFLESFFSRYVEYDFTANLEEQLDRISNNEISWQQVLKDFWNGFIGAVDEIKDLRVAQVLDVLDDMLGQHIYPPRADGGDIRQCPSCGNGRLNLKAGKFGAFVGCSNYPECRYTRQLAADSEATADRSLGQDPDTGRDVWVKAGRFGPYIQLGEQKDYEEGEKPKRAGIPKGTSPGDVELELALKLLSLPREIGKHPETGQPITAGLGRFGPFVKHEKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKAIGDHPTLGTVTVKSGRYGAICHRRRRQRDDPGRVRKGHRHAAAGDRTD
(280) DNA topoisomerase 1 [Nitrobacter hamburgensis X14]
1
MFAPKPSAHLSRNRPRVFPLSYWNNMNIVIVESPAKAKTINKYLGASYEVLASFGHVRDLPAKNGSVDPDANFQMIWEVDPKAVGRLNDIAKSLKGADKLILATDPDREGEAISWHVLEVLKQKRALKDQKIERVVFNAITKQAVTDAMKNPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCSREIEIEKFVPREYWSLIATLATPRGDTFEARLVGADGKKIQRLDIGSGAEAEDFRKAIEAANFIVSTVEAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDIGGETTGLITYMRTDGVQIDGSAITQARKVIGEDYGNAYVPDAPRQYQTKAKNAQEAHEAIRPTDLSRRPADMKRRLDADQARLYELIWIRTIASQMESAELERTTVDIAARAGSRVLELRASGQVIKFDGFLALYQEGRDDEEDEDSRRLPAMSDGEALRRENLSVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLYGEDKGRVVVAFLENFFARYVEYDFTANLEEQLDRISNNEVSWQQVLKDFWNDFIGVVNEIKDVRVSEVLDVLDNMLGPHIYAPREDGGDPRQCPTCGTGKLNLKAGKFGAFVGCSNYPECRYTRPLAADGEAGGDRILGKDPESGLDVTVKSGRFGPYIQLGEPSDYGEGEKPKRAGIPKNTSPADMELDLAVKLLSLPREIGKHPETGEPITAGIGRFGPFVRHEKTYASLEAGDEVFDIGLNRAVTLIAEKIAKGPSRRFGADPGKPLGEHPTLGSVAVKSGRYGAYVTAGGVNATIPSDKTQDTITLPEAIALIDERAAKGGGKPKRAAKKAKSAGTERTGKAGAVAAKPAKKAAAKQASVKPKSAAVSKARGSIAAVKPPAKAEKAPAKKSAGKNG
(1149) DNA topoisomerase 1 [Xanthobacter autotrophicus Py2]
1
MQVVIVESPAKAKTINKYLGPGYEVIASYGHVRDLPSKDGSVDPDADFRMLWEVDPKAQKRLNEIATAVKGADGLILATDPDREGEAISWHVLEVLKQKKALKDQKVERVVFNAITKQAVLDAMKAPRAIDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIETFVQKEYWSILARLATPRAEEFEARLTGADGKKITRLSVGTAEEAKAFRAALEAADFRVRSVEAKPMRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDVGGETVGLITYMRTDGVDMAPEAVAATRSAIGKQFGPKYLPGVPRKYTTKAKNAQEAHEAIRPTDPSRHPREVARHLDGEQAKLYELIWIRTVASQMESAELERTTADIEAKAGGRTLDLTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSANEKLNRRDILTTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLESFFKRYVEYDFTADLEEKLDEVSAAELDWKEVLRAFWQDFHTAVEATKDLRVSQVLDALDEMLTAHIFPPTQDGSDPRLCPTCGNGRLSLKMGKFGAFIGCSNYPECRHTRPLTGDGAPEGDGKRELGIDPESGEDVTIRAGRFGTYLQLGEGKDGEKPKRSSLPKGLAPADVDLETALKLLALPREVGKHPEDGEPILAGIGRYGPYVQHGRTYANIEDGDDILAIGLNRAVVLIAEKQSKGRGGRGAATPGRTLGDHPTLGGPVTVRPGRFGPYVNHGKVNATLPKSVDPEALTLAEAVTLIDAKAALSPSKAKAPRKAATKAAASGEDAPAKAATKTAAKKPAAKSAAKKTATKQPAAKKTTKTASKGPKAAE
(140) DNA topoisomerase [Methylobacterium sp. 4-46]
3
MFFFEKPSAMRELQRFFRAPTTVCIAAEGHLLAAQEPAEIRPAWKAWRFEDLPIAVDEIPLCCGQSRSGASHAARIAAIRRALDGVERVIIATDPGREGSMIAWEVLEHLGYRGRVDRLRLGALDEVSIRRAFAALGRDPDSGERDYAAYQEALCRRYEDWHLGLNGTRAVSLRLRPAAFREPWRFGGVQTPTLALLADLERRIRDFVPREFFRIALPVATVSGAELTLWHAPKERIFAREEAEAIAAAARGWAGPLAVAERDVRRPPPRLFSKDTLARRCAKSFGFDPQRTASLAQDLYDRGFLSYPRTESEHLPESQSGDAPAVLAALGASLPDLAGLVPAPGAVVLRRGPRGHYVKDPGEHHAIVPLRKVPRPGEVGPEAWRLWELVAKAFLAAHLPDGIDARTTVSAEVATALGPKRFAVTGSVVRAPGWRAVYGAEAEDEEPVPGKAKREDEPSAGRLPPVAPGEAARAGEARVEGAMTEPPRRITRGELPVVMGRLIDQVEDPALKRALENPANPNEPRGLGTAATRDAVLPKLEKSGYVVLGGALPADARAGAGGNAPRRRRDTPGRADRGGGGARGRDPTITVTEAGLAFIDAVRRVFPAYGDPVGRAVFEADLAEIGRAATRAEAVSRAETFRQRTRARLDALIAAVAGLERAAVEGPAAAPAGRPPSDAMVAFATALAARKNLPLPRGVARDAAVCRRFLDAHAEKREPTAPGAPRPPTPAMLRYAESLAREAGLPDLPEEARTEFAACRAFLDAHARPAPAEARERAGPRRPGAGRPRRRPARSPRARTAGTALGEPA
(167) DNA topoisomerase 1 [Methylobacterium sp. 4-46]
1
MKVVVVESPAKAKTINKYLGHDYEVLASFGHVRDLPAKDGSVDPEQDFKMLWELEERGAKRVSEIARAVKGADTLILATDPDREGEAISWHVLEALQAKRVLKDVAVERVTFNAITKDAVQTAMANPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFKPREYWSLVATLATAKGATFEARLVGADGKRIQRLDVGTAEEAEAFRRDLELATFAVASVESKPAKRHPQPPFTTSTLQQEASRKLGLAPAQTMRIAQRLYEGVEIGGETVGLITYMRTDGVDMAPEAIRDARRVIGAEFGDAYLPGAPRSYSVKAKNAQEAHEAVRPTDLGRLPKEVARFLEPEQAKLYELIWIRTIASQMESAELERTVVEIAAQVGPRRLDLRATGQVVRFDGFLTLYQEGKDDEEDEESRRLPPMQAGDPLRRERVAATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQVLRDREYVRLDKKRLVPEDKGRLVTGFLESFFQRYVEYDFTADLEEQLDRISNAEIDWREVLRDFWRDFSAALAGTKELRTAEVLEALNQLLGPHIFPPRADGANPRACPNCAGGTLSLKLGKFGAFVGCSNYPECKYTRQLSAAGLDGDGEGSAGEGGQPGVRVLGEDPATGLPVTLRDGRFGPFVQLGEASAEKGAEKPKRSSLPRGLTPADVTLETALKLLALPREVARHPESGEPILVNLGRFGPYVQHGKTYANLGKDDDLLEIGANRAIDLIVAKEQGGGRPAADPGRVLGNDPEGRAVTVKAGRYGPYVTDGEVNATLPKGADKEALTLEEALRLIVARREAGGGTKKKTSGRARAARKTEAKPAAKAKAEKAAKPAAAGKSASAGKSASAAKSATAPEKAPARKKAAAAE
(1512) DNA topoisomerase 1 [Methylobacterium radiotolerans JCM 2831]
1
MKVVVVESPAKAKTINKYLGRDYEVIASFGHIRDLPPKDGSVDPEQDFRMVWELADRGASRVSEIAKAVKGADKLILATDPDREGEAISWHVLEALTARKALKGIPVERVTFNAITKASVEQAMRKPREIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWTLIATLTTADGATFEARLVGADGKRIQRLDVGTGEEAAAFRRDLELATFQVASVEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQRLYEGVDIGGETVGIITYMRTDGVDMAPEAIQDARRVIGKEFGDRYVPDVPRKYSVKAKNAQEAHEAVRPTDMGRLPKTVARHLEPEQARLYELIWTRTMASQMESAELERTTVDVTAKVGPRTIDLRATGQVVKFDGFLTLYQEGKDDEEDEESRRLPPMKAGDPLTRERISATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVKIEKKRLQPEDKGRLVTGFLESFFRRYVEYDFTAGLEEQLDRVSNAEIDWRAVLRDFWRDFSAAIGETKELRVADVLEALNGLLGPHIFPDKGDGSNPRTCPTCGSGQLSLKLGKFGAFIGCSNYPECKYTRQLSATGIDGDGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFLQLGEASTEKGAEKPKRSSLPKGLSPSDVDLNKALALLALPREVARHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRLAADPGRPLGKDEASGRDLVVKAGKYGPYVTDGEVNATLPKTMSAEALTLDEAIALVNAKRAAGGGKPAKRGAARKSSARAASGDKPAAKKTATKKPAAKKAATKKSSSG
(70) DNA topoisomerase 1 [Methylobacterium nodulans ORS 2060]
1
MKVVVVESPAKAKTINKYLGHGYEVLASFGHVRDLPAKDGSVDPEQDFKMLWELEDRGAKRVSEIARAVKGADKLILATDPDREGEAISWHVLEALQAKRVLKDVSVERVTFNAITKDAVQTAMAQPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIEAFRPREFWSLVATLATARGAVFDARLVGADGKRIQRLDIGTAEEAEAFRRDLELATFTVGNVEAKPARRHPQPPFTTSTLQQEASRKLGLAPAQTMRIAQRLYEGVEIGGETVGLITYMRTDGVDMAPEAIQDARRVIGAEFGDAYVPAAPRSYSVKAKNAQEAHEAVRPTDLGRLPKEVARFLEPEQARLYELIWIRTVASQMESAELERTTVDIAAQVGPRRLDLRATGQVVKFDGFLTLYQEGKDDEEDEESRRLPSMAAGEALRRERIAATQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQVLRDREYVRLDKKRLVPEDKGRLVTGFLESFFRRYVEYDFTADLEEQLDRISNAEIDWRAVLRDFWRDFSAAIAGTKELRTAEVLEALNQLLGPHIFPPRADGANPRACPNCASGTLSLKLGKFGAFVGCSNYPECKYTRQLSAAGVEGEGDGSSGEGGQPGQRVLGEDPATGLPVTLREGRFGPFVQLGEASAEKGAEKPKRSSLPRGLSPAEVSLETALKLLALPREVARHPETGEPILVNLGRFGPYVQHGKTYANLGKGDDLLEIGANRAIDLIVAKEQGGGRPAADPGRVLGNDPESGRAVTVKAGRYGPYVTDGEVNATLPKGADRDAITLDEALRLIAARREAGGGTKKKATTRTRKSETAAKPAGKATKKAPTKASAAKKKAAAE
(1787) DNA topoisomerase [Methylobacterium nodulans ORS 2060]
3
MARASADRTLFFFEKPSAMRQLQRFFKAPTTICVSAEGHLLAAQEPAAIRPAWKAWRFDDLPIALDEIPVAYARNRSGASHAGRIEAIRGALQGVDRVIIATDPGREGSMIAWEVLEHLGYRGRVERLRLGALDEVSIRRAFAALAREPDSGERDYAAYLEALCRRYEDWHLGLNGTRAVSLRLRPPAFREPWRFGGVQTPTLAILADLERRIRDFVPRDFFKVAMPVETETGAALTLWHAPKERIFDRAEADAIREAAAGWSGPLSVVQKDVRRPPPRLFSKDTLARRCAKRFGWDPQRTAATAQDLYDSGFLSYPRTESEHLPESQSGDAAAILAAIAGCLDDVAELVPAGEAIVVRRGPRGHYVKDPGEHHAIVPLRKVPRRGELGPEAWRLWELVAKSYLAAHLPDGIDARTTVAAEVATPPGPKRFAVTGSVVRAPGWRAVYGSEAEDEDPVPGKARRDDEPTTGRLPPLRDGAAARATDATVETAVTEPPRRITRGELPVVMGRLIDQVEDPVLRRALENPANPNEPRGLGTAATRDAVLPKLEKSHYVVLAKGKDPAITVTEAGLAFIDAVRRVFPAYGDPVGRAVFEADLAEIGRAPSRAEAVRRAEEFRQRTRARLDALIAAVAGSERLAVAAPSPDGAGRPPTPAMVAFATALAARKGLRLPRGLKQDAAICRRFLDAHAEQREAAAPGAPRPPTPAMRRYAEALARENGLDKLPDDAATDFSACRRFLDAHAAPRPDAPAKPSPRKPAPRRRTRPPAGADRHADTSN
(798) DNA topoisomerase 1 [Methylobacterium populi BJ001]
1
MKVVVVESPAKAKTINKYLGRDYEVLASFGHIRDLPAKDGSVDPEADFAMVWELEDRGSKRVSEIARAIKGAEKLILATDPDREGEAISWHVIEALSARKALKGIPVERVTFNAITKASVDAAMRKPREIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWSIVATLATEAGGVFEARLVGADGKRIQRLDVGNAEEAAAFKRDLELATFQVASVEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQKLYEGVDVGGETVGIITYMRTDGVDMAPEAISDARRVIGREFGDDYVPGAPRKYSVKAKNAQEAHEAVRPTDMGRLPKQVARYLEPEQAKLYELIWTRTIASQMESAELERTTVEVTASVGPRRIDLRATGQVVKFDGFLALYQEGKDDEEDEDSKRLPAMAAGDPLKRERIASTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVKIEKKRLQPEDKGRLVTGFLESFFKRYVEYDFTASLEEQLDRVSNAEIDWRSVLRDFWRDFSAAIGGTKELRVAEVLEALNGLLGPHIFPEKADGGDPRACPTCGSGQLSLKLGKFGAFIGCSNYPECKYTRQLSASGVEGEGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFVQLGEASSEKGAEKPKRSSLPKGTSPGSVTLEIALRLLSLPREVAKHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRPSSDPGRALGPHPDGAALVVKAGKYGPYVSDGSVNATLPKTMAAESLTLEQAIELINAKRASGGGKKPVRKTATRARTATKAADGAEAKKPAVRKTASKTASKSTTKAAAKPAAAKKAAAKTKAS
(1580) DNA topoisomerase [Parvibaculum lavamentivorans DS-1]
4
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGSSKRGASRPRRSGRKGS
(46) DNA topoisomerase 1 [Parvibaculum lavamentivorans DS-1]
1
MDVVIVESPAKAKTINKYLGKGFKVLASYGHVRDLPSKDGSVLPDQDFAMAWDVDAKSQKRLNEIATAVKGADRLILATDPDREGEAISWHVLEVLNKKKVLKDVEVQRVVFNAITKKSVTEAMEHPRGLDKELIDAYLARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICDRELEIEAFRSQEYWTVEADMKTGGGSPFVARLTVLDGKKLDKFDIPDKKSADDIEARIKASRFSVKSVESKPTRRNPNPPFTTSTIQQEASRKLGFSASRTMQVAQRLYEGVEIDGETTGLITYMRTDGVQIAPEAIAQARTVINNEFGEAYLPDAPRVYTTKAKNAQEAHEAIRPTDLSRLPKHAAKYLDDDQRRLYELVWNRTIASQMESVQLERTTIEIEADDAPIGLRATGSVIVFDGFLRLYQEGRDEPDDGEDGGRLPKVARGDKLGLEKVRPEQHFTEPPPRFTEASIVKRMEELGIGRPSTYASTLQTLRDRDYVHMDKNRLVPQDKGRLVTAFLENFFTRYVEYDFTAELEEKLDKVSAGELDWKDLLREFWKEFTVNVAEALELRITEVLDRLNEVLGPHVFPEKEDGSNPRACPSCGNGILSLKVGRFGAFVGCSNYPDCKFTRQLTVGAEGEEQAGDRVLGTDPETGAEVSLKTGRFGPYVERAPLGDDEKPKRSGLPAKMSAADVDLDTALRLLTLPREIGIHPETGKKITAGLGRFGPFVLHDGTYANLKDPEELFDIGLNRAIAVLAEKVIRAEERAGKVLKELGDHPDTGKPVQVREGKYGPYIKHGTTNATLPKSADPAAVTLEEALALVAEKDAKSGKKKPAAKKAAKKPAAEKKPAAKKAPAKKPEKKKAPAKKKAPAKKPAAKARKTDKASELAD
(701) DNA topoisomerase 1 [Nitrobacter winogradskyi Nb-255]
1
MNIVIVESPAKAKTINKYLGTSYEVLASFGHVRDLPAKNGSVDPDANFQMIWEVDPKAAGRLNDIAKSLKGADKLILATDPDREGEAISWHVLEVLKQKRALKDQKIERVVFNAITKQAVTEAMKSPRQIDGALVDAYMARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRELEIEKFVPREYWSLVTTLATPRGETFDARLVGADGKKIQRLDIGNGAEAEDFRKAIEAANFTVSTVEAKPARRNPQAPFTTSTLQQEASRKLGFAPAHTMRIAQRLYEGIDVGGETTGLITYMRTDGVQIDGSAITQARKVIGEDYGHAYVPEAPRQYQTKAKNAQEAHEAIRPTDLSRRPSDMKRRLDADQARLYELIWIRTIASQMESAELERTTVDIAARAGARTLELRASGQVVKFDGFLALYQEGRDDEEDEDSRRLPAMSEGEALRRENLSVTQHFTEPPPRFSEASLVKRMEELGIGRPSTYASILQVLKDRGYVKLEKKRLYGEDKGRVVIAFLENFFARYVEYDFTANLEEQLDRISNNEVSWQQVLKDFWDDFIGVVNEIKDVRVSEVLDVLDNMLGPHIYAPREDGGDPRQCPTCGTGRLNLKAGKFGAFVGCSNYPECRHTRPLAADGEAGGDRVLGKDPESGLDVAVKSGRFGPYIQLGEASDYGEGEKPKRAGIPKNTSPADIELDLAVKLLSLPREIGKHPETGEPITAGIGRFGPFVRHEKTYASLEAGDEVFDIGLNRAVTLIAEKVAKGPSRRFGADPGKPLGDHPTLGPVAVKSGRYGAYVTAGGVNATIPSDKTQDTITLPEAIALIDERAAKGGGKPKRAAKKAKPAQTEKAGKDGAATKKPAKKAASKQASTKPKSEAVSKARGSIAAAKAPPNTVKAPTKKSAGKNG
(1792) DNA topoisomerase 1 [Mesorhizobium loti MAFF303099]
1
MDVVVVESPAKAKTINKYLGKNYKVLASFGHVRDLPAKDGSVRPDEDFAMSWAVDTASGKRLADIAKAVKDADGLILATDPDREGEAISWHVLEVLKQKRALKDKPVSRVVFNAITKSSVLEAMANPRQIDAPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFIREEYWQIAAILGTPRNETFEARLTAFERKKLQKLDIANKAQADDIKAMLEGATFKALSVEAKPTKRNPGPPFTTSTLQQAASSGLGFSATRTMQVAQRLYEGMEIGGETTGLITYMRTDGVQMAPEAIDAARDAIAKEFGPKYLPEKPRFYTTKAKNAQEAHEAIRPTDFMRTPASVRQYLDSDQMRLYELIWKRAIASQMQPAEIERTTVEIEAVNGARTAELRAVGSVVRFDGFIAAYTDQKDDDAEDEENRRLPEIRAGEQLARQAINATQHTTEPPPRYSEATLIKKLEELGIGRPSTYTAILKTLEDRDYVTIDKRRLVPQAKGRLLSAFLESFFERYVEYDFTASLEEKLDEISDGKLAWKDVLRDFWKDFSGAVADIKELRVTDVLDALNEELAPLVFPAREDGSNPRICPKCGTGNLSLKLGKFGAFVGCSNYPECSFTRQLGDAANPNGENGGGDDGTKVLGKDPYTAEEITLRSGRFGPYLQRGDGKDAKRSSLPKGWTPETIDHEKALALLALPRDIGKHPETSKMISAGLGRYGPFVLHDGTYANLDSIEDVFSIGLNRAVTVIAEKQSKGKGGRNGGTPAALKELGDHPDGGGKIVVRDGKYGPYVNFGKVNATLPKGKDPQSVTIEDALALIAEKEAKGGGGKKPFRKAAAAKAPAAKKTAARKPAAKKKG
(1539) DNA topoisomerase 1 [Bartonella henselae str. Houston-1]
1
MNIVIVESPAKAKTINKYLGSQYKVVASFGHVRDLPAKDGSVLPDQDFSMKWDVDSAAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPVKRVVFNAITKKSVLDAMNNPRDIDTSLVNAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSITTDLKTIRNDGFQARLTMFNQKKIGKLDIQSQEQADQIRLMLEKAKYHALSVEAKPTKRNPFPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGEMAGLITYMRTDGVQIAPEAIDSARKVIHESFGSDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRIPNQVRNFLDSDQAKLYELIWKRAVASQMRSAEIERTTVEIEAQQGENYANLRATGSVIRFDGFLSLYTDQRDEENNEENETTRLPQINTGEELTKEKVDAIQHTTEPPPRYSEASLIKKLEELGIGRPSTYASTLATLSDRGYIIIDKRKLIPDVKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNASITNIQELRITNVLDVLNVTLAPLAFPVREDGSDVRSCPLCTNGQLSLKLGRYGAFVGCSNYPECKYTRQLGTDPGEENEAIRNDEPVILGVDPKTGKDVTLRNGRFGPYIQLGESKEAKRAGLPKEWQAEKITLEKALSLISLPREIGIHPETGKTITATIGRYGPYLTHDGKYAPLLNVDEVFDIGINRAVTVLAEKQENKTKRSRTTTAALATLGNHPDGGVVTVRNGRYGPYVNWGKVNATLPKDKDPINVTLSEALELISVKASGKKTTLKRASTKTKET
(540) DNA topoisomerase 1 [Beijerinckia indica subsp. indica ATCC 9039]
1
MNVVIVESPAKAKTINKYLGKDYEVFASFGHVRDLPPKDGSVDPDHDFAMLWDVDTKSAKRLADIAKAVKEADRVILATDPDREGEAISWHVLEVLKAKKVLKDKPVERVVFNAITQSAILDAMRHPRAIDIDLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCERELEIERFVPREYWSLTAFLRTPADQPFSAKLVGADGKKINRLDIGAGAEAEAFKAALETAKFTVAKVEAKPARRNPAPPFTTSTLQQEAARKLGLAPARTMQLAQRLYEGIDLDGETVGLITYMRTDGVDLAPEAITGARKVIAAEYGDKYVPQAPRRYQVKAKNAQEAHEAIRPTDLARLPKHVARFLDAEQARLYDLIWTRTIASQMESAELERTTVDILAEVGARRLDLRATGQVVRFDGFLKLYQEGRDDEEDEEGGRLPAMQVGDPLKKDRIEASQHFTEPPPRFTEATLVKRMEELGIGRPSTYASTLAVLKDREYVRIDKKRLIPEDKGRLVTAFLESFFGRYVGYDFTADLESSLDKISNHEIDWKQVLRDFWADFSGAIADTKDLRTTQVLDSLNEVLGPYIFPDKGDGSNPRACPSCANGQLSLKLGKFGSFIGCSNYPECKFTRTLSDTGPEGGNGETDRPGVKVLGVDAETGEEISLRDGRFGAYVQRGEGEKPKRASLPKTIAPADLTLDMALGLLSLPREVARHPETHEPILAGIGRFGPYVQHGKTYANIGKDEDILTLGANRAIDLIIAKESGLTGRRFGKGESAPARVLGDHPEGGQVTIKAGRFGPYVNYGKLNATLPKDADPTTLTLEEGLALLAAKASGQGGGKGAVQGQLLGEHPSGGPITVREGRFGPYVNHGKVNATLKSGLSPETLTLEEAIRLIDEKAGAASKKAPAKKAPAKKASGKTTTTEKAPAKKAASKAATAKTTKAKAAKSSEPDEEPPF
(1206) DNA topoisomerase 1 [Rhizobium leguminosarum bv. viciae 3841]
1
MNVVVVESPAKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDSASAKRMKDIADALKSSDGLILATDPDREGEAISWHVLDMLNKKRALTGKSVKRVVFNAITKKAVLDAMAAPRDLDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNISALLKTPRGDEFEAKLVSASGKRLQPRAIGNGEDAGRLKALLEGASYVVDSVEAKPVKRNPGPPFTTSTLQQAASSNLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARSAIVDQFGERYMPEKPRFYSTKAKNAQEAHEAIRPTDFDRSPDRVRKFLDADQIRLYELIWKRGIASQMASAEIERTTAEITADNKGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDEDGRLPEINAREALAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLIPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKQVLRDFWKDFFAQIEDTKELRVTNVLDSLNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPDCNYTRQLSSENGGEADGAALNEPKNLGTDPTTGEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGKHPESGKMISSGIGRYGPFLLHDGSYANLETVEDVFSVGLNRAVTVIAEKAKQAPGRGARGTPAALKTLGDHPDGGAITVRDGKYGPYVNWGKVNATLPKGKDPQAITVEEALALIAEKAGKAPASKTAKAKAKPKAAAAAAKSTKTAAKPKATKAKAPAKSKKG
(1817) DNA topoisomerase 1 [Sinorhizobium meliloti 1021]
1
MFQRMSMNVVVVESPSKAKTINKYLGPGYKVLASFGHVRDLPAKDGSVRPDEDFEMSWEVDGASAKRMKDIADAVKSSDGLILATDPDREGEAISWHVLDLLRKKKVIGDKPVKRVVFNAITKKAVLDAMAEPRDIDASLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVTEEYWNISALLKTPRGDEFEARLVSADGKRLPPKAIGNGEEANRLKSLLDGASYVVESVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIEAARQAIGSQFGERYLPEKPRFYSTKAKNAQEAHEAIRPTDFDRTPDQVRRFLDGDMLRLYDLVWKRGIASQMASAEIERTTAEIVADNAGKKAGLRATGSVIRFDGFIAAYTDMKEDGEQADDGDEDGRLPEINARENLAKQKINASQHFTEPPPRYSEATLIKKMEELGIGRPSTYAATVTTLIDRDYVEIDKRKLVPQAKGRLVTAFLESFFTRYVEYDFTASLEEKLDQISAGELNWKDVLRDFWKDFFSQIEDTKELRVTNVLDALNEELAPLVFPKREDGGDPRICQVCGTGKLSLKLGKYGAFVGCSNYPECNYTRQLSSDSNGDAEAAAANEPQSLGKDPHTGEEITLRNGRFGPYVQRGDGKEAKRASLPKGWTPAAIDHEKALALLSLPRDIGPHPESGKMISTGIGRYGPFVLHNGTYANLESVEDVFSIGLNRAISVLADKQSKGAGGGRASAAALKELGEHPDGGAITVRDGRFGPYVNWGKVNATLPRGKDPQSVTVEEALALIAEREAKGGVTKGKAAKGKPTGGKSAGTKSAKAASAGTAKAEKPKSAAKTKTKAAAKAKKD
(1560) DNA topoisomerase 1 [Brucella abortus A13334]
1
MGREFRLLYMNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEILRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGRDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEQITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(86) DNA topoisomerase 1 [Brucella ovis ATCC 25840]
1
MNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKTVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAITKSFSAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFAGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYIIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRVTNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRDIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
(1055) DNA topoisomerase 1 [Methylobacterium extorquens AM1]
1
MKVVVVESPAKAKTINKYLGRDYEVLASFGHIRDLPAKDGSVDPEADFAMIWEVEDRGAKRVSEIARAVKGAEKLILATDPDREGEAISWHVIEALTARKALKGIPVERVTFNAITKASVDAAMKKPRQIDQALVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVVEREMEIERFKPREYWSIIATLVTEAGGVFEARLVGADGKRIQRLDVGNAEEAAAFKRDLELATFQVASIEAKPAKRHPQPPFTTSTLQQEASRKLGMAPAQTMRVAQRLYEGVDVGGETVGIITYMRTDGVDMAPEAIQDARQVIGREFGDAYVPSAPRKYTVKAKNAQEAHEAVRPTDMGRLPKHVARHLEPEQAKLYDLIWTRTIASQMESAELERTTVEVSANVGPRRIDLRATGQVVKFDGFLALYQEGKDDEEDEDAKRLPAMKAGDALKRERIASTQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLQTLRDREYVRIEKKRLQPEDKGRLVTGFLESFFKRYVEYDFTASLEEQLDRVSNAEIDWRSVLRDFWRDFSAAIGGTKELRVAEVLEALNGLLGPHIFPEKADGGDPRACPTCGAGQLSLKLGKFGAFIGCSNYPECKYTRQLSASGVEGEGDGSSAEGGQPGVRVLGDDPATGLPVTLRDGRFGPFVQLGEASAEKGAEKPKRSSLPKGTTPGSVTLEIALRLLSLPREVAKHPETGEPILANLGRFGPYVQHGKTYANLGKDDDVLEIGANRAIDLIVAKEQGGGRGRPSSDPGRTLGQHPDGAALVVKAGKYGPYVSDGSVNATLPKTMAAESLTLEQAIDLVNAKRASGGGKKPVRKTASRARAPAKKAEAGEAKKPAVRKTAAKPAAKATATKAAAKPAAAKKATAKTKAG
(531) DNA topoisomerase [Methylobacterium extorquens AM1]
3
MPQRLFIAEKPALGRAIATALATLSGARPSAGRGFIEVGGDCVTWTIGHAYDTAEPGDYSSTWDKWSLDVLPMLPERWKLVPNAEIADQIAVLKDRIRRYDHFVNVGDAEREGQLIVDEILIENGVDPFSPKVSRVWVSSFVEKDVAAAVAGAFPNSQKKSLYEAAVARQRADWLLGMNMSRVFGLMVQQSGARGFRVSVGRVQTPTLKLVVDRDWQIENFKAVDHFAPSITFVHENGTFKAAWQFPADTKGLDPEGRLLDKAVAQALVQKIAGKTGTVESYSETPKSTSPPLPFALSTLQKACSQKFGLTAQQTLDVAQELYEKHKAITYPRSDSQHLPNSVHTDEADGILRNLAGVRELADAAGRANPKLKSPAFDDKKVTDHHGIIPTSEASASKLAAMGEIERKVFLLIARTFVAQFHPDFRYVSSAATVLCEGERFKATGTRVVDQGWKTVFGAEEADEEEEAEGTLPSMKMKDPVDAKAGSIDPKRTKPPAHFDDGTLVEAMAKIHLYVQDQEVRKRLRENDGIGTEATRASMIEKLIRAKYLERRTKGKRKILVSTDAGRQLVDLLPSDLVAPDTTAMWESFLERVKGGEFTLAQFMDRQTQFVRKRVQTAIAAGAIQVKGFSVEPLEGHGTECPHCRAGHLVTQLWPFDDEYKGRRFLRCDNWVKDRADNCRYKTPPEGYKEREKLEGEGNPCPACGKGVLKGGVVRKEGPNRGRPFLMCSEVDREKPDSCQHFEWKDETPCPSCGKGVLKRGVVRKEGPNKGRPFAMCSAVDRTNPDGCQHFSWLDEKAAKGPKIKGEGELCTVCGKGTMMRRTGRTSGKPFLSCSNWKQGASDSCDNRVFPDDGGRRPAGGASAAPAARPRGGRPSPGGGKRSFAKAR
(883) Putative DNA topoisomerase [Methylobacterium extorquens AM1]
3
MADLFVIEAPFKAQLLEGILRELHVDAKVQATRGHFMSMPGKLRPLGIDCRMREFMRVPANPEVFMRLRDMARSADNLYIATDADQEGDVIAWDVYEAVRDIHPSPARVRLKSMDHASIREAIAAAGPVEKAAAVPGRARGIIDRMIGGVFGSPEVPAGRVSTAILGLVASRGLSVTKVRLAAPSKDRGRPWLAEFDLAAPLDLPTAERLAKLDLPPLGSRGSPVVHPTKPSHTGDILVRAGDRLDISPAEAAASLQRSYEAGRMSYPRAGSRGMTPETAKQIAGIFRKSGWTAVKTENFAAKGEDETHEAPHPIGAVDPRLNPGRLGQDEGVRTLVAADLVKAGMEHKRETAFAQDLAPFLRAQGLPGEVADFVAGLRPGRDGATLTWHREHGPAYPGQEVWARSGIERRRPDTVLLEAVVKAGLGRPSTWPRHVQTFMDRGLADDDLKLTPRGRAWVEGSYAPLLDPRLSAAIEVACERVDPSLFDDPDREPWEVMVDQIVNLLPPSVRDPLREAVAHEPPRQKIDWVGKLDARPDLVGRLAQYVSRPEYAPDL
(1142) DNA topoisomerase 1 [Agrobacterium radiobacter K84]
1
MMNVVVVESPAKAKTINKYLGPGYTVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDPASQKRMKDIADAVKSSDGLFLATDPDREGEAISWHVLDLLNKKRVINGKPVKRVVFNAITKKAVLDAMADPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNLSAILKTPRGDEFEARLVAANGKRLQPRAIGNGEEAGNLKALLEGASYVVDTVEAKPVKRNPSPPFTTSTLQQAASSKLGFSASRTMQVAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARTAIADQFGNRYLPEKARLYSTKAKNAQEAHEAIRPTDFDRTPDRVRKYLDADQLRLYDLVWKRGIASQMASAEIERTTVEILADNGGQKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDADDEDGRLPEINARENLAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLLPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKDVLRDFWRDFFAQIEDTKELRVTNVLDALNEALAPLVFPKREDGSDPRICQVCGTGNLSLKLGKYGAFVGCSNYPECNYTRQLSSEGGTEAEASGLNEPKALGTDPVTNEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGKHPESGKMISSGIGRYGPFLLHDGSYANLETVEDVFTVGLNRAVTVLAEKQSKAGGGRGTPAALKDLGAHPDGGGSITVRDGKYGPYVNWGKVNATLPKGSDPQAITVEEALALIVAKAGKSGGGKPARAPAKAKTKTAAAASKTTKTTAKPKAKAATKAKTTKKSAE
(1542) DNA topoisomerase 1 [Bartonella grahamii as4aup]
1
MNIVIVESPAKAKTINKYLGSQYKVVASFGHVRDLPAKDGSVLPDRDFSMKWDIDSSAAKRLNEIAKAVKEADSLILATDPDREGEAISWHILDVLRQKKVLKDKPIKRVVFNAITKKSVLDAMNNPRDIDTSLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRIICDRESEIEHFIKEDYWSVTTQLKTIRNDSFQARLTMFNQRKIGKLDIQSQEQADQIRFMLEKSQYHTLSVEAKPTKRNPLPPFTTSTLQQAASSKLGFSASRTMQIAQKLYEGIEINGETAGLITYMRTDGVQIAPEAIDSARKVIHETFGKDYIPEKPRFYSTKAKNAQEAHEAIRPTDFQRNPSQVRNFLDSDQAKLYELIWKRAIASQMRSAEIERTTVEIEAQQGENRANLRATGSVIRFDGFISVYTDQRDEENNEENETTRLPQVNTGEALTKEKVESVQHTTEPPSRYSEASLIKKLEELGIGRPSTYASTLATLCDRGYIVIDKRKLIPDAKGRIVTAFLENFFNRYVEYGFTADLEEKLDLISDGKLSWKDVLRDFWDGFNASISNIQELRITNVLDVLNVTLAPLAFPEREDGSDVRSCPLCKNGQLSLKLGRYGAFVGCSNYPECKYTHQLGTDTGEENEAVRNDEPVILGIDPETGKDISLRNGRFGPYIQLGESKEVKRAGLPKEWQAENVTLDKALALLSLPREIGVHPESGKTITATIGRYGPYLSHNGKSARLLHADEVFDIGINRAVTVLAEQQENKTKQSRATPAALAILGEHPEGGTITVRNGRYGPYVNWGKINATLPKDKDPISVTLPEALELISAKASSKKTTSKRASSKTKAKIKET
(1357) DNA topoisomerase 1 [Rhizobium etli CFN 42]
1
MNVVVVESPAKAKTINKYLGSGYKVLASFGHVRDLPAKDGSVLPDQDFEMLWEVDGASAKRMKDIAEAVKSSDGLFLATDPDREGEAISWHVLDMLNKKRVLNGKSVKRVVFNAITKKAVLDAMADPRDIDVPLVDAYLARRALDYLVGFNLSPVLWRKLPGARSAGRVQSVALRLVCDRESEIERFISEEYWNISALLKTPRGDEFEARLVSAHGKRLPPRAIGNGEDAGRLKALLEGASYIVDTVEAKPIKRNPGPPFTTSTLQQAASSNLGFSASRTMQIAQKLYEGVDIGGETVGLITYMRTDGVQMAPEAIDAARRAILDQFGERYLPEKARFYSTKAKNAQEAHEAIRPTDFNRSPDRVRKFLDADQIRLYELIWKRGIASQMASAEIERTTAEITAENKGEKAGLRAVGSVIRFDGFIAAYTDQKEDGEQSDDGDEDGRLPEINARETLAKQKINSTQHFTEPPPRYSEASLIKKMEELGIGRPSTYAATLATLRDRDYVTIDKRKLIPQAKGRLVTAFLESFFTKYVEYDFTADLEEKLDRISAGELNWKQVLRDFWKDFFAQIEDTKELRVTNVLDSLNEALAPLVFPKREDGGDPRICQVCGTGNLSLKLGRYGAFVGCSNYPECNYTRQLSSENGGEAEGVALNEPKSLGTDPTTGEELTLRSGRFGPYIQRGDGKEAKRASLPKGWKPEDIDYEKAMALISLPRDIGRHPETGKMISSGIGRYGPFLLHDGSYANLETVEDVFSVGLNRAVTLIAEKASKAPGRGARGTPAALKTLGDHPDGGAITVRDGKYGPYVNWGKVNATLPKGKDPQAITIEEALALITEKAGKAPAGKTARGKAKPKAAAAEAKTTKTAAKPKAAKAKAPAKLKKS
(1663) DNA topoisomerase 1 [Brucella canis HSK A52141]
1
MGREFRLLYMNVVVVESPAKAKTINKYLGSDYKVLASFGHVRDLPAKDGSVRPDEDFAMSWEVDSNSAKRLADIVKALKDSDGLILATDPDREGEAISWHVLEVLRQKKALNGKTVKRVAFNAITKKAVLDAIAHPRDIDEPLVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREAEIERFVREEYWNIAALLKTPRNDSFTARLTALDGKKLGKLDIKNGEQAGAIRTMLESANFKAVSVEAKPTKRNPGPPFTTSTLQQAASGQLGFSASRTMQVAQRLYEGVDIGGETAGLITYMRTDGVQIAPEAINAARDAIAKSFGAKYVPEKPRYYSSKAKNAQEAHEAIRPTDFSRHPKDVRRFLDEDQARLYELIWKRAIASQMQAADIERTTVDIEATNGSRAAMLRANGSVTKFDGFLAAYMDHREEEDDDEESAKLPEIRSGEALAREKIDATQHSTEPPPRYSEATLIKKMEELGIGRPSTYAATLATLRDREYTIIDKRKLIPEAKGRLVTAFLESFFERYVEYDFTADLEEKLDLISDGKLSWKEVLRDFWRAFSGSVEDIKELRITNVLDALNEELAPLVFPAREDGSDPRSCPTCGTGTLSLKLGRYGAFVGCSNYPECKYTRQLGGEANGETAASDEPKPLGKDPFTGEEITARTGRFGPYIQRGEGKEAKRASLPKGWTLDTVDHEKAIALLSLPRNIGLHPETGKMISAGIGRYGPYVSHDGTFANLENVEEVFSVGLNRAVSVLADKQSKGGGRGRSTPAALATLGDHPDGGAITVRDGRYGPYVNWGKVNATLPKGKDPASVTLEEALALITEKAGSSKGRKAPARKSAASSEKKTTAKKTATKKAPAKAKSKAKAAEE
Family distribution
Taxonomy tree
Rhizobiales