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Taxon : Enterobacteriales
Informations
Name
Enterobacteriales
Rank
order
# topoisomerases
149
Lineage and sub-taxa
Lineage
Bacteria
>
Proteobacteria
>
Gammaproteobacteria
>
Enterobacteriales
Sub-taxa
Topoisomerases
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Name
Family
Sequence
(1016) DNA topoisomerase 3 [Shigella flexneri]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEAGSGAIA
(1727) DNA topoisomerase 1 [Shigella flexneri]
9
MGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1015) DNA topoisomerase 3 [Shigella flexneri]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEAGSGAIA
(1033) DNA topoisomerase 1 [Shigella flexneri]
9
MGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVHKDHALTLVELTPVHHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGRATGWSAFYVDGKWVEGKK
(442) DNA topoisomerase 3 [Photorhabdus luminescens subsp. laumondii TTO1]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGDNQFVTWCIGHLLEQAEPDAYDNRFARWSLVDLPIIPEKWQLKPRPSVEKQLNIIQTLLEKADEIVHAGDPDREGQLLVDEVLDFLKLDAVRRKNVRRCLISDLNPQAVTRAVDRLRDNRDFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPILGLVVRRDEEIEHFVPKDFFEVKAHIVTPKDERFIAIWQPSESCIDFLDEEGRLIHRPLADHIVTRITGQPAYVISYQDKRESEVAPLPFSLSSLQIEAAKRFGLNAQQVLDICQRLYETHKLITYPRSDCRYLPDEHFAGRHAVLNAISIHATKLLPQELLEIDRKNRCWDDKKVDAHHAIIPTARSSHINLTDSEANIYGLIARQYLMQFFPDAIFRKCVIELEIAGGKFIAKARFLAEAGWRTLLGNKERDEENDGTPLPVVAKGDELLCERGEVVERQTQPPKPFTDATILSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKREFLYKKGRHIHATPAGRALIHVLPDMAALPDMTAHWESRLTQISEKQFRYQDFMGPLEETLQQLIWQAKQNRNLTAFRDLPPLPVKDKKGKKIKAPKNTKRAAP
(1735) DNA topoisomerase 1 [Photorhabdus luminescens subsp. laumondii TTO1]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSASQKSSSSSTDKSKKKVKKDEKAVLVNRMGVDPYRGWEANYQILPGKEKVVAELKSLAEKVDHVYLATDLDREGEAIAWHLREVIGGDGDRFSRVVFNEITKNAIKQAFDNPGELNIHRINAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPVEYWQLHADLLAKGEISLHMEVTHQQGKPFKPVNSEQTQAAVSLLEKARYKVLDREDRPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALDMVRDYISDNFGDKYLPEAANTYSSKENSQEAHEAIRPSSVDIVAEQLKDMDVDAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFELRAKGRTLRFDGWTKVMPVLRKGDEDHTLPVVEIGTELDLQQLIPSQHFTKPPARYSEASLVKELEKRSIGRPSTYASIISTIQERGYVRVESRRFYSEKMGEIVTDRLEENFNELMSYDFTARMEDQLDQVASNKVEWKGVLDEFFTDFSEQLDVANKEPEEGGMRPNPMVITSIECPTCQRSMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNVLEGDEAETNALRARRRCKKCGTAMDSYLIDSQRKLHVCGNNPACDSYEVEEGEFRIKGYDGPVIECDKCGAEMHLKMGRFGKYMGCTNETCKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKERLPEKLRYLADAPVVDAEGNKTVIRFSRKTKQQYASSEKNGKATGWSVFYVDGKWVEKDKK
(1061) DNA topoisomerase 1 [Edwardsiella ictaluri 93-146]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKGAASAGDKAKTKAKKNERDALVNRMGVDPYHGWQAHYEVLPGKEKVVSELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDGSRYSRVVFNEITKNAIQQAFSQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWELRADLAVGADVSFQAQVTHYNDKPFKPVNAAQSQAAVTALENARFAVREREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRAYIGDNFGAEYLPTDANVYASKDNSQEAHEAIRPSDVSVLADDLKGMEADALKLYQLIWRQFVSCQMTAAKYDASTITVQAADYTLKARGRTLRFDGWTRVLPQLRKGDEDRALPAVESGRALDLLQLQPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRTDNRRFYAEKMGEIVTDRLEENFRELMSYDFTAHMEDGLDRVASAQADWKVMLDGFFSDFSQQLEVAEKPPEEGGMRPNPMVLTCIACPTCERQMGIRTASTGVFLGCSGYTLSPKERCKTTINLVPEAEVLNVLEGDDAETNALRAKRRCPKCGTAMDSYLIDNHRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGAEMHLKMGRFGKYMGCTNEACKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLAEAPQQDAQGNATLVRFSRKTKQQYVSSEKDGKATGWTAFFIDGKWVVSEKK
(1169) DNA topoisomerase 3 [Edwardsiella ictaluri 93-146]
10
MRLFIAEKPSLGRAIADVLPKPHRRADGYIQCGDGDVVTWCVGHLLEQAEPDAYDARYARWNLVDLPIVPQKWQLRPKASSAKQLKVIERLLRDAQQVVHAGDPDREGQLLVDEVLDFLALAPEKRRQVQRCLINDLNPQAVARALERLRDNHEFMPLCVSALARARADWLYGINMTRAYTLLGRNAGYNGVLSVGRVQTPVLGLVVRRDEEIAHFVAKDYYEVRAHIVTPSGERFWAQWQPSEACEPHQDEEGRLLNRALAEHVIARIQDKPARVTGYNDKRESEVAPLPFSLSALQIEAAKRFAMSAQQVLDICQRLYETHKLLTYPRSDSRHLPEEHFAGRHAVMAAIATHAPTLANLESVDVQRRNRCWDDNKVDAHHAIIPTARAGGVTLNEDERNIYQLVARQYLMQFCPDAQYRKCVIDLEIEGGGFIAKARFLSQAGWRALLGAKERDDEDEGMPLPVVARDDLLHCERGELMARQTQPPRHFTDATLLSAMTGIARFVQDKSLKKILRATDGLGTEATRAGIIELLFRRGFLHKKGRYIHASQTGSALIHCLPEMAGRPDMTAHWESTLTKISERGCRYQDFMHPLVETLQQLIHQARTAVNPRAFRDLPPIENGRSRRTKGTTASNKRKKA
(1383) DNA topoisomerase [Edwardsiella ictaluri 93-146]
4
MQLYLCEKPSQAKDIARVLGISKRGQGFISADNITVTWAIGHLLEQASPDAYGEQFGKPWRVDVLPVLPDNWKMVVKPQTRDQFTVISKLLKQAGEVIIATDADREGEVIARELLAYCGYRGAVRRLWLSALDEASIREALAGILPGENTAKLYDAGLGRSRADWLIGMNLTRLYTLIARESGVSDVLSVGRVQTPTLAIVVNRDKEIADFVPVPWWQVQVLLEKDGVRFRATWQAAAQYCDDEKRCVNKQAANAVGQLCQQQKGATVLEVSQKRDKTPAPLCFDLGTLQLVCSRKFGMGAKETLAVAQSLYETHKATTYPRTDCGYLPTSMQKEIPEVMGSVAKSDPSVAPVLAQLDRGFVSRVWNDKKITAHHAIIPTRQAFDLSRLSADELKVYQLIRQHYFAQFLPLQESDVTDASFNIGGQLFLAKGKVNVITGWTCLFQKEIQEDPPEDDDMALPALNKGDSCIVNGASVGDKVTSPPKPFTEGTLIAAMKNAASFVSDPKLKKVLRDNAGLGTEATRAGVLETLFSRHYLEKKGKHIHATLLARELIAALPETLTSPGMTALWEQALDDIAQGKMSLDTFIQKQLQWTRHLVDKGRADTVKITAPVTPPCPVCKGLTRKRKGKNGDFWGCIRYPECNGIVAGKSGGKGRKIARGKKTVVNTEVELSASQ
(955) DNA topoisomerase 3 [Erwinia amylovora CFBP1430]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNGRFARWSLADLPIVPEKWRLQPRPSVAKQLNVIKGLLSQASVVVHAGDPDREGQLLVDEVLDYLTLPAEKHAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVAKDFFEVRAHIVTPADERFVALWQPSDSCEPYQDDEGRLLHRPLAEHVVARIGGQPAHVTSYNDKRENETAPLPFSLSALQIEAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRHLPDEHFAGRHAVLNAINIHLPNLTPPGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQVALSDHERQIYCLIATQYLMQFCPDAIYRKCVIELAIAGGKFLAKARFLAEAGWRALLGSKERDEENDGTPLPVVTRGDELLCERGEVLEKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRSFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFMSPLVETLHSLIQQARQQPAAYAFRGLPAPATDKTKRPRRKTAQKKESET
(568) DNA topoisomerase 1 [Erwinia amylovora CFBP1430]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGTTVKKSTDSTTSKPTKKVKKDEKTALVNRMGVDPFHGWAANYQILPGKEKVVSELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRHAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINRDQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMARGYIEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMETDAQKLYQLIWRQFVACQMMPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNQAQWKAVLDKFFGDFSQQLEQAEKDPEEGGMQPNQMVVTSIECPSCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPVVECEKCGGEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPRVEELQRFRDRLPEKLRYLADAPAEDAEGNKAVVRFSRKNKQQYVSTEKEGKATGWSAFYVDGKWEVAKK
(79) DNA topoisomerase 1 [Erwinia tasmaniensis]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPISGSTVKKSTDSTTSKTTKKVKKDAKTALVSRMGVDPFHHWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIHQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWDLNADLTTPKGIDLPMQVTHQHDKPFRPVNRDQTYAAVSVLENARFTVVDREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYVEDEFGAKYLPKTANIYSSKENSQEAHEAIRPSDVKIQSEQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDERTLPAVEVGSELSLQQLLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKTVLDKFFGEFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCDKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEDCKNTRKILRNGDVAPPKEDPVPLPELVCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAEDADGNKSVVRFSRKTKQQYVSTEKDGKATGWSAFFVDGKWEVAAKK
(1269) DNA topoisomerase 3 [Erwinia tasmaniensis]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGGDQVVTWCVGHLLEQAQPDSYNSRFARWSLADLPIVPEKWRLQPRPSVAKQLNVIKGLLEQASVVVHAGDPDREGQLLVDEVLDYLTLPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVAKDFFEVRAHIVTPADERFVALWQPSDSCEPYQDEEGRLLHRPLAEHVVARINGQPAHVTSYNDKRENDTPPLPFSLSALQIEAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINLHQPDLSAPTDFNSDQKNRCWDDKKVDAHHAIIPTARSGQVRLTDNEGQIYRLIATQYLMQFCPDAVYRKCVIELDIAGGKFLAKARFLAEAGWRALLGSKERDEENDGTPLPVVAKGDALLCERGEVLEKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAQWESTLTKISEKQCRYQDFMSPLVETLHSLIHQARQQPAAHAFRGLPPPASDKVKKTRRKTTKKKESEA
(517) DNA topoisomerase [Erwinia sp. Ejp617]
4
MRLFICEKPSQGRDLAAVLGATQRGDGFLAGSGITVTWAVGHLLETAPPEAYGQQYGKPWTLAALPIIPSPWQVVVKKETQHQFKIIERLLRQVDEVIIATDADREGEVIARELLDYCRWEGPVQRLWLSSLDELSIRAALQNLRPGGETLGMYHAGLGRARADWLTGMNLSRLYTLRAAEAGFDGVVSVGRVQSPTLALVVRRDREIAAFVPKPYWQVKAQLSAGGITFPAQWVPAKVYTDEEKRCIHQNIAQQVVQICRQSGEATVTECETKREKASPPLAFSLGTLQQAASRLWDMSPQQVLDTAQSLYEKHKATSYPRTDCGYLPESMREEIPALLDAIGRTDPECLPLLSQLDASLVSRIWNDKKITAHHGIIPTRNAFQLSALSETERQVYMLIRRNYLAQFLPLHESDITRLAFDIGGQLFRTTGRTEVVKGWKVLFGKAEEEGSAADDEAVVALPPLKKDDRCGVTGAEVVQLMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRRFIVRKSSKLLATDLGSDVIDSLPPQLTEPGMTALWEQALDEVAAGRMSLSDFLQRQTGWTRNLVSQGAQQQVSIRIPPTPPCPLCGGKTRLRKGQKGDFWSCQRYPDCKGVINIGSGKRKSPRKAKSPKPNKN
(407) DNA topoisomerase 3 [Erwinia sp. Ejp617]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNSRFARWSLDDLPIVPEKWRLQPRPSVAKQLNVIKGLLTQASVVVHAGDPDREGQLLVDEVLDYLTLPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVAKDFFEVRAHIVTPADERFVALWQPSASCEPYQDEEGRLLHRPLAEHVVARIGGQPAHVTSYNDKRENETAPLPFSLSALQIEAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINVHQPNLSPPGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQVSLSDNEQQIYRLIATQYLMQFCPDAVYRKCVIELDIAGGKFVAKARFLAEAGWRALLGSKERDEENDGTPLPVVTKGDELLCERGEVQEKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFMSPLVDTLHSLIQQARQQPAAHAFRGLPASATDKTKRPRRKTAQKKESET
(377) DNA topoisomerase 1 [Erwinia sp. Ejp617]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKTTKKVKKDEKTALVNRMGVDPFHGWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRQAFDRPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVDREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINREQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYVEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMEADAQKLYQLIWRQFVACQMVPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKAVLDQFFGDFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALSPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYDIEQGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAKDADGNKAVVRFSRKTKQQYVSTEKDGKASGWSAFYVDGKWEVTKK
(1698) DNA topoisomerase 3 [Enterobacter aerogenes KCTC 2190]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDGRYARWNLLDLPIVPEKWQLQPKPSVTKQLNVIKRLLGEAQEVVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQDERFIATWVPSEACEPYQDEEGRLLHRPLAEHVVKRIEGQPAIVTGYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAISVHAPDLLPQPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLNDNEEKVYNLIARQYLMQFCPDAVFRKCQIDLDIANGKFVAKARFLAEAGWRALLGNKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRGFLNKKGRYIHSSDAGRALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRQFRGLVAPGGAKKSFSKGKGKPKGKKPEADIAPESPQ
(1358) DNA topoisomerase 1 [Enterobacter aerogenes KCTC 2190]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERGALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDASTTTPGGDALPLQVTHKNDKPFRPVNRDETMAAVALLEKALYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGKKYLPENANQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGEFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPVVNQGDNLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKQVLDNFFGDFTSQLQTAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFFIDGKWTEAKK
(717) DNA topoisomerase 3 [Klebsiella variicola At-22]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLTDLPIVPEKWQLQPKPSVTKQLNVIKRLLGEAQEVIHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFVATWVPSEACEPYQDEEGRLLHRPLAEHVVKRIEGQPALVTGYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAADLLPQPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLTDNEAKVYHLIARQYLMQFCPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKDDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSSDAGRALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRQFRGLAAPGGAKKSFSKGKGKPKGKKAADDAAPPPQ
(972) DNA topoisomerase 1 [Klebsiella variicola At-22]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSTDSTATKGAKKPKKDERGALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVIHKDDKPFRPVSRDETMAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYISDNFGKKYLPESANQYASKENSQEAHEAIRPSDVSVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPVVKQGDRLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKEVLNHFFGDFTTQLETAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFFIDDKWTEAKK
(1590) DNA topoisomerase 3 [Klebsiella pneumoniae KCTC 2242]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDIYDSRYARWNLNDLPIVPEKWQLQPKPSVTKQLNVIKRLLGEAQEVIHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFVATWVPSEACEPYQDEEGRLLHRPLAEHVVKRIEGQPAIVTGYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAADLLPQPVVDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLTDNEAKVYTLIARQYLMQFCPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCERGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLSKKGRYIHSSEAGRALIHSLPEMAGRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQARSTPVRQFRGLVAPGGAKKSFSKGKGKPKGKKAADDTAPPPQ
(730) DNA topoisomerase 1 [Klebsiella pneumoniae KCTC 2242]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTATKGAKKPKKDERSALVNRMGVDPWHDWNAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVTHKDDKPFRPVSRDETMAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYISDKFGKKYLPDSANQYASKENSQEAHEAIRPSDVNVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPLVKQGDRLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKEVLNHFFGDFTTQLATAEKDPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFFIDGKWTEAKK
(1417) DNA topoisomerase 3 [Enterobacter asburiae LF7a]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLNDLPIVPEKWRLQPRPSVTKQLNVIKRFLHEASEVIHAGDPDREGQLLVDEVLDYLELAPEKRQQVQRCLINDLNPQAVERAISRLRANSEFIPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPKEERFTATWQPSDACESYQDEEGRLLHRPLADHVVNRITGQPAIVTSYNDKRESEPAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHYAGRHSVMNAIGVHAPDLLPQPAVNPDTRNRCWDDKKVDAHHAIIPTARTSNVNLTENESKVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGNKERDEENDGTPLPVVAKDDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKKGRYIHSTEPGRALIHSLPELAARPDMTAHWESILTQISEKQCRYQDFMQPLVGTLYQLIDQARSTPVKTFRGMVAPGGGAKKPFKKKKSAA
(1116) DNA topoisomerase 1 [Enterobacter asburiae LF7a]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVNPWHNWDAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDANVTTPGGDALPLQVSHQNDKPFRPENREQTMAAVALLEKARYQVLEREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESANQFASKENSQEAHEAIRPSDVSVLAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDELSLVDLVPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDSLDQVASHQAEWKKVLDSFFSDFTNQLDKAEKDPEEGGMLPNQMVLTSIDCPTCGRKMGIRTATTGVFLGCSGYALSPKERCKTTINLVPENEVLNILEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWAEGKK
(1591) DNA topoisomerase 3 [Enterobacter lignolyticus SCF1]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLTDLPIVPEKWQLQPRPSVTKQLNVIKRLLQDASEVIHAGDPDREGQLLVDEVLDYLNLAADKRQQVQRCLINDLNPQAVERAISRLRANSEFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPADERFTALWQPSEACEPYQDEEGRLLHRPLADHVVSRISGQPAMVTAYNDKRESEPAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRQAVLNAISVHAPDLLPQPAVDPEVRNRCWDDKKVDAHHAIIPTARSSSVKLSDNEANVYGLVARQYLMQFCADAVYRKCQIDLDIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVEKGAELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLVKKGRYIHSTEAGRALIHSLPEMAGRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLFSLIDQARRTPVKQFRGLVAPGGDKKKTFARKGGKRKTAAE
(755) DNA topoisomerase 1 [Enterobacter lignolyticus SCF1]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSATKKSADSASTKTAKKPKKDERGALVNRMGVDPWHDWKAQYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDTRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFVDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDASTTTPSGEVLPLQVSHYLDKPFRPVTRDETMAAVSLLEKARYSVVEREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRGYISDSFGKKYLPESANQYASKENSQEAHEAIRPSDVNVMAEALKDMETDAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDYKLKARGRTLRFDGWTKVMPALRKGDEDRTLPPVKQGDALSLVELQPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKEVLNDFFGDFTRQLETAEKGPEEGGMQPNPMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCAKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELHRFRDRLPEKLRYLADAPQEDGQGNKTMVRFSRKTKQQYVASEKDGKATGWSAFFVDGKWQEAKK
(947) DNA topoisomerase 1 [Enterobacter sp. 638]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVDPWHEWEAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREIIGGDETRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANVTTPAGDALPLQVTHENDKPFRPVNRDHTMAAVAQLEKARYQVVEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVTMVRDYIGENFGKKYLPESANQYASKENSQEAHEAIRPSDVSVVSESLKDMETDAQKLYQLIWRQFVACQMNPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPPVNKGDELSLTELLPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDRLDQVANHQAEWKNVLDSFFSDFTEQLAKAEKDPEEGGMQPNQMVLTSIDCPTCSRQMGIRTATTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLRMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPLQDPEGNKTVVRFSRKTKQQYVSAEKEGKATGWSAFFIDGKWVEGKK
(224) DNA topoisomerase 3 [Enterobacter sp. 638]
10
MRLYIAEKPSLARAIADVLPKPHRKGDGFIECGKGQVVTWCIGHLLEQAQPDVYDSRYARWNLNDLPIVPEKWRLQPRPSVTKQLNVIKRFLHDAAEIVHAGDPDREGQLLVDEVLDYLELAPEKRKQVQRCLINDLNPQAVERAISRLRSNNEFIPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPKDERFVAVWQPSEACEPYQDEEGRLLHRPLAEHVVNRIAGQPAIVTSYNDKRESEPAPLPFSLSALQIEAGKRYGMSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIGVHTPDLLPQPAVNLETRNRCWDDKKVDAHHAIIPTARASNVNLTENESKVYQLVARQYLMQFCADAMFRKCVIELEIAKAKFVAKARFLAEAGWRTLLGNKERDEENDGTPLPVVAKNDELLCEKGEVIERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLIKKGRYIQSTDPGRALIHSLPELAARPDMTAHWESILTKISEKECRYQDFMQPLVGTLFDLINQARTTPVKNFRGMVAPGGAKKPFKKKKSAA
(1627) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Typhi]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLSVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(150) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(148) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(1628) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Typhi]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLSVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(149) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(94) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAEETGRQTE
(1228) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(196) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Newport str. SL254]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAEETGRQTE
(1239) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Newport str. SL254]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFMLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1332) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
10
MANWSRPAAVALWLRFVNLMRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAKETGRQTE
(896) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQLLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(500) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
7
MDLYICEKPSQAKDLAGVMKASQRGDGFIHDGGNRVITWAFGHLLELYMPDDYDERYKSWSLETLPIAPDAWRYNVRKSALKQYKIVEGLVKKASTIYISTDFDREGEAIARSLLDQFRYSGPIRRVCLTALDESSIKKALNNVKDGKETVSLYYAALARQRADWLVGMNVSRLYTVLARDVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEECSDEQGRCINKAYAEQVSSQVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGYTAQQVLDAAQALYETHKATTYPRTDSRYLPESQKENIPDILQALILSDQNVSGLVAGADPHRKARVFNDSKVTAHHAIIPTPARTDISAMSEIELNLYDAIRRFYIAQFYSEFEFTKTSIEVQCGRHLFAASGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALLNGTELMNKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGTVDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVATGSGNMSVFMKQISTWICQMVDQLKVAAPVLTKEGSAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWGCQNEACKKTFPDNRGKPEKRIAAEDCPDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKSDL
(316) DNA topoisomerase 3 [Xenorhabdus nematophila ATCC 19061]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIECGNNQFVTWCVGHLLEQAEPDAYDSRYARWVLTDLPIIPEKWQLKPRPAVAKQLNTIKSLLERASEIVHAGDPDREGQLLVDEVLDFLDLDAEKKQNVQRCLINDLNPQAVIKAVERLRNNREFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFVPKDFFEVKAHIVTPSEERFTAIWQPSESCIDFQDEEGRIIHRPLAEHVVARITGQPAIVTAYQDKRESETAPLPFSLSSLQIEAAKRYGLSAQDVLDICQRLYETHKLITYPRSDSRYLPEEHFTGRHAVLNAISVHAAHLLPQDALDTERKNRCWDDKKVDAHHAIVPTARSSQVNLTKNENDIYSLIARQYLMQFFPDAIFRKCTIELDIAGGKFIAKARFLAEAGWRTLLGHKERDEENEGTPLPIVAKGDELLCEKGEMVERQTQPPRPFTDATLLSAMTGIARFVQDKALKKVLRATDGLGTEATRAGIIELLFRREFLYKKGRHIHATPAGRALIHVLPDMAVLPDMTAHWESRLTQISEKQFRYQDFMSPLQETLQQLIRQAKQYRNLKAFRDLPPVPAKGKKGKQLKSSKSKNR
(549) DNA topoisomerase 1 [Xenorhabdus nematophila ATCC 19061]
9
MAKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGAASQKSSISSTDKNKKKVKKDEKTALVSRMGVDPYHDWEANYQILPGKEKVVAELKTLAEKAEHVYLATDLDREGEAIAWHLREVIGGDDARFSRVVFNEITKNAITQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWQLHADLVAKGEIALRMEVTHEKGKPFKPVNAQQTHAAVSLLEKAKYSVIDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALDMARGYISTHFGDKYLPKEGNVYSSKENSQEAHEAIRPSNVEVMAEELKDMEADAQKLYQLIWRQFIACQMMPAKYDSTTLTVQAGNFELRAKGRTLRFDGWTKVMPVLRKGDEDNTLPAIEANTELDLQQLFPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVNDRLEENFNELMSYDFTARMEDQLDHVANNEANWKGVLDEFFSNFSEQLDVASKEPDEGGMRPNPMVITSIDCPTCCRAMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNILEGDDAETNALRARRRCKKCGTAMDSYLIDNQRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGSEMHLKMGRFGKYMGCTNEECKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLHYLAEAPVADPEGNKTVVRFSRKTKQQYVSSEKNGKATGWAAFFVEGSWAVKEK
(1543) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGGSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILPGEQTESLWQAGLGRARADWLTGINLTRLYTLKAQEQGFGEVLSIGRVQTPTLALVVNRDNDIARFEQKPYWQVMATLQKDDISFRAKWLPAPDDGDEEKRCIREDIAQRVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGTLQQVASRQWGMGAGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDASAFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVTFTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTALPALKKEEISPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(1717) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MQLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCHFTGPVRRLWLSALDETSIRQALAAILPGEKTAPLWQAGLGRARADWLTGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMATLQKDDISFRAKWLPAPDDGDEEKRCIREDIAQSVVQRCQQTQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDASAFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVTFTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTALPALKKEEISPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(50) DNA topoisomerase [Xenorhabdus nematophila ATCC 19061]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILPGEKTESLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVVATLQKDGIGFRVKWLPAPDDCDEEKRCIKEDIAHSVVQCCQEAQNAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHPFDMTKLTADELKVYQLIRQYYLAQFLPAQETDVTDVTFTIGGQVFQATGRVSVVTGWKALFADEKQAQDQDGNTALPVLKKAETCPVIRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVIGSRKTRRGNSPD
(1671) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAAETGRQTE
(284) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1883) DNA topoisomerase 3 [Salmonella bongori NCTC 12419]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWSLADLPIVPEKWQLQPRPSVTKQLNVIKRFLQDAGEIVHAGDPDREGQLLVDEVLDYLQLPAEKRQRVQRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMKAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYALIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPIVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVRQFRGIIAPVGEGKKKSAPRKRPAKKSPPQA
(844) DNA topoisomerase 1 [Salmonella bongori NCTC 12419]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFDKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGDALPLQVTHQNDKPFRPVSREQTLAAISLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVSVMAESLKDMEADAQKLYQLIWRQFVACQMTSAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKSDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVIRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWVEGKK
(743) DNA topoisomerase [Serratia plymuthica AS9]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
(369) DNA topoisomerase 3 [Serratia plymuthica AS9]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGNNDVVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNAIKKLLHDADEVVHAGDPDREGQLLVDEVLDYLALTPEKRHSVRRCLINDLNPQAVERAIDRLRDNRDFIPLCVSALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPKEERFVALWQPSDSCEPYQDEEGRLLHRPLAEHVLKRIEGQPALVTSYNDKRESDTAPLPFSLSTLQIEASKRFNLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAISAHQPDLYPQPVIDSDRRNRCWDDKKVDAHHAIIPTARASKVSLSQDELNVYGLVARQYLMQFCPDAMFRKCVIELDIAGGKFVAKARFLAEAGWRTLLGSKERDEENEGSPLPVVAKDDELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKALKKILRATDGLGTEATRAGIIELLFKRAFLYKKGRYIHSSETGRALIHSLPDIAARPDMTANWEATLTQISEKSCRYQDFMQPLVGTLQELIYQAKQSRASMAFRGLPPSPSAGAKKRKKSAGKAREKSE
(1540) DNA topoisomerase 1 [Serratia plymuthica AS9]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDEKTALVNRMGVDPYHGWKADYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDEKRFSRVVFNEITKNAIQQAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKNDTALQMEVTHAHDKPFKPVNREQTHAALKLLEKARYTVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMEDGLDQVANNHAEWKAVLDEFFAEFSEQLETAEKDPEDGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNETCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADGEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1816) DNA topoisomerase 3 [Shigella boydii Sb227]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTRQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEVGSGAIA
(1810) DNA topoisomerase 1 [Shigella boydii Sb227]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(310) DNA topoisomerase 3 [Shigella flexneri 5 str. 8401]
10
MANWCQRAAVVPWLRSVNLMRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEAGSGAIA
(1024) DNA topoisomerase 1 [Shigella flexneri 5 str. 8401]
9
MRRIPGRIKLGKVNMGKALVIVESPAKAKTINKYLGCDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(366) DNA topoisomerase 3 [Yersinia enterocolitica subsp. enterocolitica 8081]
10
MMRLFIAEKPSLARAIADILPKPHRRGDGFIACGSDNMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWRLQPRPSVSKQLNVIKQLLQQADEVIHAGDPDREGQLLVDEVLDYLDLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIEDFVAKDFFEVKAHIVTPADERFIALWQPSDSCESYQDEEGRLLHRPLAEHVVNRIAGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISMHQADLLPLDVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDESKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVEKGAELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVATLQDLISQAKQNRSPQVFRGLPAAPSGAIKKRKKTSSKTKENKS
(1742) DNA topoisomerase 1 [Yersinia enterocolitica subsp. enterocolitica 8081]
9
MGKALVIVESPAKAKTINKYLGNNYVVKSSVGHIRDLPTSGSASKKSANSTEDKAKKADKPKTKVKKDEKVALVNRMGVDPYHGWKAQYEILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKGEVPIQMEVTHAHNKPFKPVNREQTHAALKLLENARYKVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPSAPNQYSSKENSQEAHEAIRPSDVNVMAEQLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSELDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKAVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPEAEILNILEGDDAETNALRAKRRCQKCGTAMDSYLIDNQRKLHVCGNNPTCDGYEIEEGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVTDNEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEAKK
(323) DNA topoisomerase 3 [Yersinia pestis A1122]
10
MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALWQPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEGKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPSGAPKKRKKISSKAKESKS
(1303) DNA topoisomerase 1 [Yersinia pestis A1122]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSANSAEEKAKKDDKPKKKVKKDEKVALVNRMGVDPYHGWKAQYEILSGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNISRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLVAKGDIPIQMEVTHAHGKPFKPVNREQTHAALTLLENARYKVLDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPATPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQRLYQLIWRQFVACQMPPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSDLDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKAVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPDAEILNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLLELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVVDKEGNKTLVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEAKK
(1001) DNA topoisomerase 3 [Yersinia pestis]
10
MMRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALWQPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTACASKVNLTTDEGKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPSGAPKKRKKISSKAKESKS
(1798) DNA topoisomerase 3 [Yersinia pestis]
10
MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALWQPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEGKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPSGAPKKRKKISSKAKESKS
(490) DNA topoisomerase 3 [Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGDNQFVTWCIGHLLEQAEPDAYDSRFARWSLVDLPIVPEKWQLKPRPSVAKQLDIIQELLKKADEVVHAGDPDREGQLLVDEVLDFLNLDGEKRKNVRRCLINDLNPQAVAKAVDRLRDNRDFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYRGVLSVGRVQTPVLGLVVRRDEEIEHFVPKDFFEVKAHIVTPKDERFTAIWQPSESCIDFQDEEGRLIHRPLAEHVVARITGQPAYVTSYQDKRESEVAPLPFSLSSLQIEAAKRFGLNAQQILDICQRLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAISVHTINLLPQDLLEVDRKNRCWDDKKVDAHHAIIPTARNSHINLTDNEANIYGLIARQYLMQFFPDAIFRKCVIELEIAGGKFIAKARFLAEAGWRTLLGNKERDEENDGTPLPVVAKGDELLCERGEVVDRQTQPPKPFTDATILSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKREFLYKKGRYIHATPAGRALIHVLPDIAALPDMTAHWESRLTQISEKQFRYQDFMKPLEETLQQLIWQAKQSRNLQAFRDLPPVPVKGKNGKKSKSGKNTKATAP
(1696) DNA topoisomerase 1 [Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSASQKSSSSSTDKSKKKVKKDEKAALVSRMGVDPYRGWEANYQILPGKEKVVAELKSLAEKADHVYLATDLDREGEAIAWHLREVIGGDSDRFSRVVFNEITKNAIKQAFDKPGELNIDRINAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWQLHADLLAKGEISLHMEVTHKRGKPFKPVNSEQTQAAVSLLEKARYKVVDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALDMVRGYISDNFGDKYLPKTANTYSSKENSQEAHEAIRPSSVDVMAEQLKDMDADAQKLYQLIWRQFVACQMTPAKYDSTTLTVQAGDFELRAKGRTLRFDGWTKVMPALRKGDEDHTLPVVEVGTELDLQQLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYSEKMGEIVTDRLEENFNELMSYDFTARMEDQLDQVASNKAEWKGVLDEFFTDFSEQLEVANKDPEDGGMRPNPMVITSIACPTCDRPMGIRTATTGVFLGCSGYALSPKERCKQTINLIPENEILNILEGDEAETNALRARRRCKKCGTAMDSYLIDNQRKLHVCGNNPACDSYEVEEGEFRIKGYDGPVIECDKCSSEMHLKMGRFGKYMGCTNETCKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADAEGNKTVIRFSRKTKQQYAASEKNGKATGWSVFYVDGKWIEKDKK
(147) DNA topoisomerase 3 [Citrobacter rodentium ICC168]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLSDLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEVVHAGDPDREGQLLVDEVLDYLQLAAEKRQQVQRCLINDLNPQAVERAIERLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFIPKDFFEVRAHIVTPADERFIAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPAFVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAIGVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSTINLSENEAKVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFIAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKSTPVRRFRGIVAPGGGSSEKKKSAPRKRAAKKSPPSAEAGL
(1777) DNA topoisomerase 1 [Citrobacter rodentium ICC168]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGDALPLQVTHQNDKPFRPVNREQTQAAVSLLEKARYTVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDSFGKKYLPDSPNQYASKENSQEAHEAIRPSDVTVLAETLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLVELIPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHEAEWKAVLDNFFSDFTQQLDKAEQDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTLVRFSRKTKQQYVAAEKDGKATGWSAFYVDGKWVEGKK
(814) DNA topoisomerase 1 [Buchnera aphidicola str. Ua (Uroleucon ambrosiae)]
1
MSKSLVIVESPAKAKTINKYLGNEYIVKSSIGHVRDLITRKFKKPTHKSQKYSQSYSLNNKQKTYFIENIGIDPYKDWKAEYSILPGKEKIISELKNIAHKVDHIYLATDLDREGEAIAWHLKEVIGGDSTKFSRVVFNEITKHAIKKAFKNITKINMHRVHAQQARRFMDRIVGYMISPLLWEKISRGLSAGRVQSVAVRIIAEREDIIKKFIPEEYWKLNVSFVLKNQNKIIMDVTHFNNKKFRPNNQNELNIAIEEIKKSSFFIKKFEKKIIYKQAPAPFITATLQQSASLILGFSVKKTMFLAQKLYEEGYITYIRTDSCYLSLNAINKVRKYIKKFYGDAYLSNKYYIHTNKKHSQEAHEAIRPSDIKVKNINTNTINLDAEKLYLLIWNQFIASQMKPAQYQFITIKIFSHLFQLQKQLKIVLFDGWTKMFKEKNENITQIPIIDIGSILNIDNIIINQKFTKPLPRFTEASLVRELEKKGIGRPSTYSVITSKIQERGYVTIKKNKFYAEKMGSILTIRLKKSFSNLIDYNFTANMEKKLDQIAENKLSWINVLNSFFKDFSEKLDQAKKNPEEGGMELNNIVFTSIKCPTCFKKMGIKNAITGVFLSCLGYQDNLKKRCKQTINLIPLNDVLKKKQNNEVTSGFTKLINKCEKCNMFMDSYFINKNIQLHICINNPSCIGYKVEKGNFKIPIWLSKTVECDKCYSNMLLKKGPFGKFFICVNIKCKNTRKILPNGEISDPKLEPIPFPELLCKKSNASFVLREGVSGIFFAASTFPKSRETRSPFIEELAKFQYLLPKKIYYLSKAPIVDDKGNKTIVCFNRKNKEYYVTSKKKGKFTGWSAVFIKNKWCVINQ
(1021) DNA topoisomerase 3 [Rahnella sp. Y9602]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGNDQVVTWCVGHLLEQAQPDAYDSRFARWSLADLPIIPEKWQLQPRSSVAKQLNVIKRLLLEASQVVHAGDPDREGQLLVDEVLDYLELTPEKRHATQRCLINDLNPQAVERAIERLRDNRDFIPLCVSALARARADWLYGINMTRAYTILGRNAGYNGVLSVGRVQTPVLGLVVRRDEDIENFVPKDFFEVKAHIVTPAEERFVALWQPSDSCEPYQDEEGRLLHRPLADHVVARIAGQPAMVTGYNDKRENDIAPLPFSLSTLQIEGSKAFGLSAQQILDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAIGVHRPDLMPQPAVDTDLRNRCWDDKKVDAHHAIIPTARSSNVNLTDDERKIYGLVARQYLMQFCPDAVYRKCVIDLDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGTPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFRREFLYKKGRYIHSSDTGRALIHSLPDIAARPDMTADWESTLTRISEKSCRYQDFMQPLVATLQNLIMQAKTNRVSSAFRSLPSKPAGAVAKGKSAPKRRKASTKGKEANSDE
(936) DNA topoisomerase 1 [Rahnella sp. Y9602]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKTADSTEEKTKKKVKKDEKTALVNRMGVDPYHGWEAQYEILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKEPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLLAKKETALQMEVTHHLEKPFKPVNKEQTHAAVSLLEKARYTVVDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVEMVRGYIGENFGDKYLPKAPLQYSNKENSQEAHEAIRPSDVAVISEQLKDMEADAQRLYQLIWRQFVACQMTPAQYDSTTLTVKAGDYSLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIEVGTDLELQQLLPTQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMEDGLDQVANNKAEWKAVLDEFFTEFSKQLETAEKDPEEGGMRPNQMVLTSIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGDEAEANALRAKRRCVKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELKRFKDRLPEKLSYLADAPVADPEGNKSMVRFSRKTKQQYVSSEKDGKATGWTAFFVDGKWVEGKK
(418) DNA topoisomerase 3 [Rahnella aquatilis CIP 78.65 = ATCC 33071]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGNDQVVTWCVGHLLEQAQPDAYDSRFARWSLADLPIIPEKWQLQPRSSVAKQLNVIKRLLLEASQVVHAGDPDREGQLLVDEVLDYLELTPEKRQATQRCLINDLNPQAVERAIERLRDNRDFIPLCVSALARARADWLYGINMTRAYTILGRNAGYNGVLSVGRVQTPVLGLVVRRDEDIENFVPKDFFEVKAHIVTPAEERFVALWQPSDSCEPYQDEEGRLLHRPLADHVVARIAGQPAMVTGYNDKRENDIAPLPFSLSTLQIEGSKAFGLSAQQILDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAIGVHRPDLMPQPAVDTDLRNRCWDDKKVDAHHAIIPTARSSNVNLSDDERKIYGLVARQYLMQFCPDAVYRKCVIDLDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGTPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFRREFLYKKGRYIHSSDTGRALIHSLPDIAARPDMTADWESTLTRISEKSCRYQDFMQPLVATLQNLIMQAKTNRVSSAFRSLPSKPAAAKGKSAPKRRKASTKGKEANSDE
(1587) DNA topoisomerase 1 [Rahnella aquatilis CIP 78.65 = ATCC 33071]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKTADSTEEKTKKKVKKDEKTALVNRMGVDPYHGWAAQYEILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKEPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLLAKKETALQMEVTHHLEKPFKPVNKEQTHAAVSLLEKARYTVVDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVEMVRGYIGENFGDKYLPKAPLQYSNKENSQEAHEAIRPSDVAVTSEQLKDMEADAQRLYQLIWRQFVACQMTPAQYDSTTLTVKAGDYSLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIEVGTDLELQQLLPTQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVHVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMEDGLDQVANNKAEWKAVLDEFFTEFSKQLETAEKDPEEGGMRPNQMVLTSIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGDEAETNALRAKRRCVKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELKRFKDRLPEKLSYLADAPVADPEGNKSMVRFSRKTKQQYVSSEKDGKATGWTAFFVDGKWVEGKK
(1337) DNA topoisomerase 3 [Pantoea ananatis PA13]
10
MRLFIAEKPSLGRAIADVLPKPHRRGEGFIACGNDQIVTWCVGHLLEQAQPDVYDSRYARWSLVDLPIIPEKWRLQPRPSVAKQLKVVEGLLAQADEVVHAGDPDREGQLLVDEVLDYLQLPAEKRSKVQRCLINDLNPQAVERAINRLRENREFIPLCVSALARARADWLYGINMTRAWTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIANFVPKDYFEVKAHIVTPDESRFTANWIPSEACEPWQDEEGRLLKRSLAEHVVARISGQPAIVTAYSDKRENDIAPLPFSLSSLQIEAAKRFGLSAQAVLDICQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAIQSHQPDLTPPADFDADRKNRCWDDKKVDAHHAIIPTARASAVKLNENEQQIYGLVARQYLMQFCPDAVFRKCTIDLDIAGGKFVAKARFLAEAGWRALLGGKERDEENDGMPLPVVAKDDELLCERGEVLAKQTQPPRHFTDATLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFRRSFLHKKGRYIHSTDAGKALIHSLPDLAARPDMTAQWESTLTRISEKACRYDEFMQPLVQTLSGLIQQARQQPSGQAFRGLPSTGQKRPPRKAGRKTKETE
(130) DNA topoisomerase 1 [Pantoea ananatis PA13]
9
MGKALVIVESPAKAKTINKYLGSGYVVKSSVGHIRDLPTSGSTAKKSAETSTDKKVKKVKKDEKAALVSRMGVDPYHGWEADYQILPNKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIRQAFDTPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELSANLTTPKGDDLAMDVTHAGDKPFRPVNHEQTHAALALLEKARFAVTDREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYIEGNFGKKYLPDNANTFASKENSQEAHEAIRPSDVDVVAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVTAGDYKLKAKGRTLRFDGWTKVMPALRKNDEDRTLPPVNVGDELSLQALLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMESSLDQVANNQAEWKAVLDRFFSDFSQQLEQAEKDPEEGGMQPNQMVLTTIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNGRKLHVCGNNPECDGYEIEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFHDRLPEKLKYLAEAPATDPEGNKTLVRFSRKTKQQYVASEKEGKATGWSAFYIDGKWQEAKK
(1818) DNA topoisomerase [Pantoea ananatis PA13]
4
MRLFLCEKPSQGRDLAAVLGASRRGEGFMTGNGVTVTWAVGHLLETAPPEVYGQQYGKPWSLSALPILPSRWQVVVKKDTQDQFKVIEKLLRQADEVVIATDADREGEVIARELLDYCGWDGRILRLWFSALDELSVRAALSDLRPGQASVGMYHAGLGRSRADWLIGMNLSRLYTLRAAEAGFEGVVSVGRVQTPTLALVARRDREIAAFVPKPYWQVKATLSASGVSFQASWVPAAVYADEEKRCIHQNIAQQVAQLCRQAGVSTVTEYETKREKEAAPLAFSLGTLQRACGKMWNMSPQKVLDTAQSLYETHKATTYPRTDCGWLPKSMREEIPAVFDAMARTDPSPEFASLLSQLDRGFASRIWNDKKITAHHGIIPTRNAVQLSSLTETERQVYLLIRRNYLAQFLPLCESDATRISFDIGGQLFRTTGRTEVLKGWKVLFTKDEEDKDTAEEDIAGSLPPLSKGAQCGVTDAEVKQLMTQPPAHYTFDTLIGAMMNAAAYVTDLQLRKILKENAGLGTEATRAGIIEQLLSRRFITLKGSKLLATDLGADVIDALPPQLTDPGMTALWEQALDEVAAGRMNLNDFLQRQTAWTSTLVSQGMQQRISIRVPPSPPCPLCGSKTALRRSPKGEFRSCTRYPECKGIISLDSGRRKSPARAKSPKTKKN
(536) DNA topoisomerase 3 [Pantoea sp. At-9b]
10
MRLFIAEKPSLGRAIADVLPKPHRRGEGYIACGNDQVVTWCVGHLLEQAQPDSYDSRYARWNLADLPIIPEKWQLQPRPSVAKQLKVIEGLLAQATEVVHAGDPDREGQLLVDEVIDYLQLPAEKRQKVQRCLINDLNPQAVERAVSRLRENREFIPLCVSALARARADWLYGINMTRAWTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFIPKDYFEVKAHIVTPKDERFVASWVPSDACEPWQDEEGRLLHRPLADHVLERINGQPARVTAYNDKRESEIAPLPFSLSSLQIEAAKRFGLSAQNVLDCCQRLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIQAHQPDMTPPADFNPEQRNRCWDDKKVDAHHAIIPTARASKVNLSENEANIYGLIARQYLMQFCPDAVFRKCVIDLDIAGGKFVAKARFLAEAGWRALLGSKERDEENDGTPLPVVSKGDELLCERGEVLAKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFRRTFLVKQGRYIHSTQAGRALIHALPEMAARPDMTAHWESTLTRISEKACRYDEFMQPLVSTLIGLIGQARQQPSLQAFRGIAASGSASEKKRTRKPARRKMKETE
(702) DNA topoisomerase 1 [Pantoea sp. At-9b]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTARKSADGEKTKPAGKKVKKDEKAALVNRMGVDPWHGWQADYQILPGKEKVVSELKSLAADADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIRQAFEKPGELNIERVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDADLVTPKGDALAMQVTHQGDKAFRPVNREQTYAAVALLQKARYDVLDREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAIAMARSYIDKNFGANYLPAAPNTYASKDNSQEAHEAIRPSDVAVAAEKLKDMEADAQKLYQLIWRQFVACQMVPAQYDSTTLTVGAGDFKLKAKGRTLRFDGWTRVMPALRKNDEDLTLPPVNVGDVLDLKEVLPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDSLDQVANNQAEWKGVLDSFFSDFSQQLDQAEKEPEEGGMQPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNVLEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPECDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFADRLPEKLKYLAEAPAADPEGNKTMVRFSRKTKQQYVASEKEGKATGWSAFYVDGSWQEAKK
(715) DNA topoisomerase 3 [Pantoea vagans C9-1]
10
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIACGNDQIVTWCVGHLLEQAQPDSYDSRYARWSLNDLPIIPEKWQLKPRPSVAKQLKVVEGLLAQASEVVHAGDPDREGQLLVDEVLDYLNLPPEKRSKVQRCLINDLNPQAVDRAVNRLRENREFIPLCVSALARARADWLYGINMTRAWTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVPKDYFEVKAHILTPDGARFVASWIPSEACEPWQDEEGRLLKRALADHVVARITGQPAIVTAYSDKRENDVAPLPFSLSSLQIEAAKRYGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPEEHFAGRRTVLKAIQAHQPQLTPPADFNADRRNRCWDDKKVDAHHAIIPTARSSAVKLSENEQHIYELVARQYLMQFCPDAVFRKCVIDLDIAGGKFMAKARFLAEAGWRALLGSKERDEENDGMPLPVVAKGDELLCERGEVLAKQTQPPRPFTDATILSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFRRGFLVKKGRYINSTDAGRALIHSLPDLAARPDMTAQWESTLTRISEKACRYDEFMQPLVQTLTGLIQQARQQPAAHAFRGLPSTGQKRPVRKTRRKVKETE
(582) DNA topoisomerase 1 [Pantoea vagans C9-1]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTAKKSADASTDKKVKDASTDKKVKKVKKDEKAALVSRMGVDPYHGWEADYQILPGKEKVVAELKALAANADHIYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVNAALTTPKGDELSMDVTHKGDKAFRPVNRDETYAAVALLEKARYEIVDREDKPTSSKPGAPYITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVAMARGYIESNFGKKYLPETAITYASKENSQEAHEAIRPSDVEVVAEKLKDMEADAQKLYQLIWRQFVACQMTPAKYDSSTITAAAGEFKLKAKGRILRFDGWTKVMPALRKNDEDRTLPAVSVGDVLDLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYAAITSTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESNLDQVANNEAQWKAVLDHFFADFTQQLELAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNERKLHVCGNNPECDGYEIEKGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRSGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFKDRLPEKLKYLADAPAADPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWQEAKK
(885) DNA topoisomerase 1 [Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum)]
9
MGKSLVIVESPAKAKTINKYLGSHYVVKSSVGHIRDLPKSGSNNKKNASEIIKKQKTEKKMFQDHQSSLIKRMGIDPYHGWKAQYEILSGKEKVVSELKALAAKADHIYLATDLDREGEAIAWHLREVIGGDPQRFSRVIFNEITQNAIQQAFKKPGELNMNRIHAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPQEYWHLEANLLTPQKIMIPMMVSHFEGEPFKPLNREQTYAAVNDLEDAQYVVLDRKDKPTSSKAGAPFITSTLQQAASTRLGFGVKKTMLMAQRLYEAGHITYMRTDSTHLSQDALSMVRNYIQKHFGNRYLISPAYEYGNKKNAQEAHEAIRPSNVDVFSEQLEDMEPDARKLYQLIWRQFVACQMTPAQYDVTTLIVEAKNYQLRAKGRTLRFDGWTKVMPALRKGDEEETLPIIAVGTSMHLEKLIPSQHFTKPPGRYSEASLVKELEKRSIGRPSTYATIISTVQERGYVRIENRRFYAEKMGEIVTNRLEENFRELMNYDFTARMENALDQIAQHQAEWKKVLDEFFSEFSEQLNIAEKDPSEGGMRPNSMVIMDINCPACGQKMGIRTASTGVFLGCSSYALPPKERCKTTLNLISENEILNLLDGDEAETNALRSRRRCEKCETAMDSYLLDTARKLHICGNNPICDGYQMEQGEFRIKGYEGPIVECDKCAHEMHLKVGRFGKYMGCTNEECKNTRKILRNGEVAPPKENPVPLPELLCEKSDAYFVLRDGAAGLFLAANTFPRSRETRAPRVEELQRFKDRLPEKWHYLVEAPLKDTEGNKTFLRFSRKTKEQYISSEKSGKATGWCAFYIDGQWVEGKKRPLVKS
(1163) DNA topoisomerase 3 [Escherichia fergusonii ATCC 35469]
10
MPWLRFVKSMRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDTYDSRYARWNLTDLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNNKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRCIVAPDGGEGNKKTSSRKRAAKKSPPADEAGSGAIA
(1194) DNA topoisomerase 1 [Escherichia fergusonii ATCC 35469]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDANTTTPSGDALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPAGNKSMVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEGKK
(824) DNA topoisomerase 3 [Escherichia coli NA114]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETYKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGGGEGKKKDSPRKRAPKKSPPSEEAGNGVII
(307) DNA topoisomerase 1 [Escherichia coli NA114]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(1300) DNA topoisomerase 3 [Cronobacter turicensis z3032]
10
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIECGNGQVVTWCVGHLLEQAQPDAYDSRYGRWNLADLPIVPEKWQLQPKPSVAKQLNVIKKLLREAQEIVHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDKLRENREFVPLSTSALARARADWLYGINMTRAYTLLGQNAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFVAKDFFEVKAHIVTPAQERFTALWQPSEACEPYQDEEGRLLNRALAEHVVKRIEGQPARVTSYNDKREGEAAPLPFSLSTLQIEASKRFNLSAQAVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVLKAIGVHASDLLPQPAVDPERRNRCWDDKKVDAHHAIIPTARSAPASLSDGEAKIYGLIARQYLMQFCQDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGAKERDEENDGTPLPVVAKGDELHCERGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKQGRYIHSTPAGKALIHALPELAARPDMTAQWESTLTQISEKQCRYQDFMQPLVHTLYTLIDQARSAPVRQFRGLVAPQQAQKRRAGKGGKKPAARKRSGAQPATE
(1760) DNA topoisomerase 1 [Cronobacter turicensis z3032]
9
MGKALVIVESPAKAKTINKYLGKDFVVKSSVGHIRDLPTSGSAPKKSAESAPTKPAKKVKKDERGALVNRMGVDPWHNWEAQYEVLPGKEKVVSELKSLAEKADHIYLATDLDREGEAIAWHLREVIGGDETRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDALLSTPKSDQLSVQVTHHKDKPFRPVNRQDTEAAVALLKAASYQIVEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVSMVRNYIGEEFGKKYLPENPNQYASKENSQEAHEAIRPSDVSVLAESLKDMENDAQKLYQLIWRQFVACQMTPAQYDSTTLTVAAGDFRLKARGRILRFDGWTRVMPALRKGDEDRTLPAVNQGDKLSLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFPELMNFDFTAQMEDSLDQVANHEAEWRGVLDTFFDDFSRQLDTAEKDPEEGGMRPNQMVLTSIDCPTCGRPMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEVEEGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFRDRLPEKLLYLADAPAQDPEGNPAVVRFSRKTKQQYVASEKDGKATGWSAFYVDGKWAEGKK
(1411) DNA topoisomerase 1 [Candidatus Moranella endobia PCIT]
9
MGTALVIVESPAKAKTINKYLGKGYVVKSSVGHIRDLPKKSPASKNKNNTCIPDQHTVLIKRMGIDPFHSWKARYEILPGKEKLVTELRALAEEADHVYLATDLDREGEAIAWHLREAIGGDEKRFRRVVFNEITRNAVTQAFENPVVLNMNRVNAQQARRFMDRIVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKSFMPAEYWELHVALQTSQAAQLMMKVTHQQEKPFKPAKQQQLQAAISILEHTDYIVSNRDDKITTSKPGSPFTTSTLQQAASLHLGYRVKKTMLLAQRLYEAGHITYMRTDSTHLSRNALNMARCYISAAFGHSYLPTQPKEYVSKNNSQEAHEAIRPSDVSALAEQLNNMEAEAQKLYQLIWRQFVACQMKPAQYNYTILTVNAGEFQLSAHGRQLMFDGWTKVMPTQHTEKDKRTLPTVKEGNNLTLNKILPSQHFTKPPARYSEASLVKELEKRGIGRPSTYVSIISTIQERGYVHADNRRFYAEKIGEIVTDRLEENFSELMSYDFTAKMEATLDQVATNQQDWKSVLDAFFSKFSQQLKNAEQNPVDGGMRLNQMIMTSINCLVCDRPMGIRTASTGVFLGCSGYQLPPKDRCKNTIHLIPESETLNRFTVGDEETNALRARRRCVKCRTAMDNYVIDSKRKIHVCGKNPLCDGYNIEQGEFIVVAYNGRVVECEKCGFNMQLKFGRFGKYIACTNNNCKNTRKILRNGDVAPPKEDPVLLPELPCYGHSDAYFVLREGAVGVFLAANTFPKYRETRKPLVAELARFRERLPVKLQYLADAPIEDDEGNSTLVRFSRKTKQQYISSEKDGKATGWTAFYVNGKWQVNRKSSGCGP
(462) DNA topoisomerase 3 [Enterobacter cloacae EcWSU1]
10
MRSVNSMRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLNDLPIVPEKWRLQPRPSVTKQLNVIKRFLHDATEVIHAGDPDREGQLLVDEVLDYLELAPEKRQQVQRCLINDLNPQAVERAISRLRANSEFIPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPKDERFTAVWQPSDACESYQDEEGRLLHRPLAEHVVNRITGQPAIVTSYNDKRESEPAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHSVMNAIAVHAPDLLPQPVVNPDIHNRCWDDKKVDAHHAIIPTARASNVNLTENEAKVYNLVARQYLMQFCPDAVFRKCVIELEIAKGKFIAKARFLAEAGWRTLLGNKERDEENDGTPLPVVAKDDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKKGRYIHSTEPGRALIHSLPELAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYELINQARNTPVKQFRGMVAPGGAPKKPFKKKKSAA
(542) DNA topoisomerase 1 [Enterobacter cloacae EcWSU1]
9
MNMGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERSALVNRMGVNPWHNWDAQYEVLPGKEKVVNELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDANVTTPGGDALPLQVSHQNDKPFRPENRDQTMAAVALLEKARYQVLEREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPESANQYASKENSQEAHEAIRPSDVSVLAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDELSLVDLVPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEANFRELMNYDFTAQMEDSLDQVASHQAEWKKVLDSFFSDFTNQLEKAEKDPEEGGMLPNQMVLTSIDCPTCGRKMGIRTATTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELHRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKEGKATGWSAFFVDGKWVEGKK
(78) DNA topoisomerase 3 [Dickeya dadantii 3937]
10
MRLFIAEKPSLARAIADVLPKPHRRSDGFIACGEQDVVTWCVGHLLEQAQPDVYDARYARWSLADLPIVPQKWLLQPRPSVSKQLNVIKKLLNQADEIIHAGDPDREGQLLVDEVLEYLSLPEEKRQHVGRCLINDLNPQAVERAVSRLRENREFVPLCVSALARSRADWLYGINMTRAYTLLGRNAGYEGVLSVGRVQTPVLGLVVRRDEEIDNFVSRDYFEVKAHIVTPADERFIALWQPSESCEPYQDEEGRLLHRPLAEHVVKRIEGQPAWVTAYNDKRESETAPLPYSLSALQIEAAKRFGLSAQQVLDVCQRLYETHKLITYPRSDCRYLPEEHFAGRQAVLNAIAAHQPDLLPQPAVDPERRNRCWDDGKVDAHHAIIPTARSARTSLTESESQVYGLIARQYLMQFCADAMFRKCVIDLDIAGGKFVAKARFLAEAGWRTLLGNKERDEENEGMPLPVVEKGDELLCERGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKALKKILRETDGLGTEATRAGIIELLFKRAFLVKKGRYIHSTEAGKALIHALPPMAAHPDMTAHWEATLTQISEKRCRYQDFMQPLTQSLHELIQQARQSGNITAFRGLPPVKRAPPAGRKRRQSRSASTKE
(253) DNA topoisomerase 1 [Dickeya dadantii 3937]
9
MGKALVIVESPAKAKTINKYLGNDFVVKSSVGHVRDLPTSGSGSASKKSAEANGEKAKKAVKKDEKTALVNRMGVDPYRGWQANYEILPGKEKVVSELKTLAQNADHVYLATDLDREGEAIAWHLREIIGGDDKRFSRVVFNEITKNAIRQAFENPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWELHADLLANPDIALQMQVTHHNGKPFRPVNQAQTQAAVSLLEKASYVVAEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALAMARDYIQDEFGKRYLPEAPNLYTSKENSQEAHEAIRPSDVKVLADQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLVVSAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPAIDVGQSLSLEKLLPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMENSLDLVANSQAEWKAVLDEFFAEFSKQLETAEQEPDEGGMKPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLIPEAEVLNVLEGDEAETNALRARRRCSKCGTAMDSYLIDNQRKLHVCGNNPSCDGYEIEQGEFRLKGYDGPVVECEKCSSEMHLKMGRFGKYMACTNESCGNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFRDRLPEKLRYLAEAPVTDPEGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYVDGKWVESSR
(459) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(305) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFLPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEEIYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(348) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Gallinarum/pullorum str. RKS5078]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(192) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Gallinarum/pullorum str. RKS5078]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(985) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEERLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAEETGRQTE
(867) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(771) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLSVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(226) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(205) DNA topoisomerase [Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12]
4
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA
(424) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1382) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAEETGRQTE
(110) DNA topoisomerase 3 [Serratia proteamaculans 568]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGNNDVVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNAIKKLLHEADEVVHAGDPDREGQLLVDEVLDYLALSPEKRHSVRRCLINDLNPQAVERAIERLRDNRDFIPLCVSALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVSKDFFEVKAHIVTPKDERFVALWQPSDSCEPYQDEEGRLLHRSLAEHVLKRIEGQPALVTSYNDKRESDTAPLPFSLSTLQIEASKRFNLSAQQVLDVCQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISVHQPDLYPQPVIDSDRRNRCWDDKKVDAHHAIIPTARASKVSLSQDELNVYGLVARQYLMQFCPDAMFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKDDQLLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKALKKILRATDGLGTEATRAGIIELLFKRAFLYKKGRYIHSSETGRALIHSLPDIAARPDMTANWEATLTQISEKSCRYQDFMQPLVGTLQELIYQAKQSRASMAFRGLPPSPSGGAKKRKKSAGKAREKSE
(93) DNA topoisomerase 1 [Serratia proteamaculans 568]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDPTTALVNRMGVDPYHGWKAHYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQNAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKGDTALQMEVTHAHDKPFKPVNREQTHAALNVLEKARYTVLDREDKPTSSKPGAPYITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALEMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAADYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMENGLDQVANNQAEWKAVLDEFFAEFSEQLETAEKEPEEGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNESCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADAEGNKTLVRFSRKTKQQYVSAEKDGKATGWSAFYIDGKWVEGKK
(1256) DNA topoisomerase [Serratia proteamaculans 568]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMTVKKETADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRATLQKGGIAFPASWVPAANYCDEEKRCIQQNVAQAVVQLCQQTGHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQALSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTQSGSVARLDRTFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEVVAGWKVLFQHDVSEAKEESTDTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKAQAVKFTAPPSPPCPTCSGTMRRRAGKKGSGAFWGCSNYPTCQGIINIDAKGGRKAKRYKAKSPAKNKTTKSE
(1882) DNA topoisomerase [Serratia proteamaculans 568]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAVKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDITNFISKPYWQVRATLQKGGITFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQYLSLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILDTLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
(1573) DNA topoisomerase 3 [Pectobacterium atrosepticum SCRI1043]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGQNDVVTWCVGHLLEQAQPDVYDARYARWSLADLPIIPQKWLLQPRPSVSKQLSAIKKLLNDASEVIHAGDPDREGQLLVDEVLDYLSLPEEKRQQVRRCLINDLNPQAVERAVSRLRENREFIPLCVSALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVSKDYFEVKAHIVTPADERFVAIWQPSESCEPYQDEEGRLLHRSLADHVVKRIDGQPAFVTSYNDKRESETAPLPYSLSTLQIEAAKRFGLSAQQVLDVCQKLYETHKLITYPRSDSRYLPEEHFTGRHAVLNAIAVHQPDLLPQPVMDIDRRNRCWDDGKVDAHHAIIPTARSASASLTENERKVYGLVARQYIMQFCPDAVFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGGKERNEENEGMPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRTFLFKKARYIHASEAGRALIHSLPASAAHPDMTAHWEATLTQISEKKCRYQDFMQPLTNSLQELIQQAKQNGAVRAFKGFSAPPSGASKRRKPQAKKAKEQDQ
(380) DNA topoisomerase [Pectobacterium atrosepticum SCRI1043]
7
MMRLFLCEKPSQGRDIARFIGATQRGKGFLSGTGTVVTWAFGHLLEVASPEEYGAQFGKPWRMDVLPILPTEWKMVVKQSSADQFAVISRLLKQADEVVIATDADREGEVLARELLDYCHFTGNVKRLWLSALDDASIRKGLDNLLPGEKTVRLYYAGMGRSKADWLIGMNLTRIYTLKASEQGIDELLSIGRVQTPTLALVVQRDSDIENFSPKPYWQVFADIEKAGMTFRAQWVPAAGYCDDEKRCIQHNAALAVEQLCKQTATTSVVDVLLKREKTPAPLCFSLSVLQKACSDKWGMIAQKVLEIAQSLYEVHKATTYPRTDCGYLPESMKGEVSDVLSAILQSDPAATSLIKDADRSFVSRIWNDKKISAHHAIIPTKQPFDISKLSDDELNVYQLIRLHYFAQFFPLHESDVTDVTFNLGGQLFKTRGRVSVVIGWKKLFFNDKEPDIQSDENGSQGSLPVLHNGDICNVLDCEVKAQQTKPPSRFTDGTLIDAMKNSASFISDPTLKKILRDNAGLGTEATRANILDVLFKRNYLKRREKFIYSTQLARELISQLPEALTNPGMTALWEQALDDVAEGRMSLDAFLQKQKEWTLRLVDRGRQQAIKLTAPVSPLCPQCGGIMRKRNSDNGVFWGCVKYPLCKGIISEGTKGKRGKKNLKTKNKPAT
(835) DNA topoisomerase 1 [Pectobacterium atrosepticum SCRI1043]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSVSKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWEANYEILPGKEKVVSELKALAENADHIYLATDLDREGEAIAWHLREIIGGDDQRFSRVVFNEITKNAITQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHNGKPFKPVNKEQTHAAVSLLENARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPEAATGYSNKENSQEAHEAIRPSDVGVLADSLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEGLSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRAENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALPPKERCKTTINLIPETEVLNVLEGDEAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTGETCSNTRKILRNGDVAPPKEDPVPLPELSCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELDRFKDRLPEKLRYLADAPVADKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(317) DNA topoisomerase 1 [Sodalis glossinidius str. 'morsitans']
9
MGKALVIVESPAKAKTINKYLGKDYVVKSSVGHIRDLPTSGSASQKSTDASKKKKGKPDAQLALVNRMGIDPYHGWKARYEILPGKEKVVTELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITRNAITQAFEQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELHADLKTAQAAPLAMQVTHQREKPFKPVNQQQIQAALDGLENADYVVSDRDDKPTSSKPGAPFTTSTLQQAASTRLGYGVKKTMTLAQRLYEAGHITYMRTDSTNLSQDALNMARGYISASFGSPYLPKQANDYASKNNAQEAHEAIRPSDVNALAEQLKDMEADVQKLYQLIWRQFVACQMTPAQYDSTTLTVTAGEFQLRARGRTLRFDGWTKVMPALRKGDEDRTLPAVEAGQTLTLIKLLPSQHFTKPPARYSEASLVKELEKRGIGRPSTYVSIISTIQDRGYVHAENRRFYAEKMGEIVTDRLEENFRELMNYNFTAKMEDTLDQVAANQQEWKQVLDAFFQEFSQQLENAEKDPEDGGMRPNQMVMASINCPVCGRKMGIRTASTGVFLGCSGYALPPKERCKNTINLIPESETLNVLEGDDAETNALRARRRCGKCGTAMDSYVIDGQRKLHVCGNNPLCDGYDIEQGEFRIKGYDGPVVECEKCGADMHLKLGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELLCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVAELARFRDRLPENLRYLADAPVKDDEGDSTLVRFSRKTKQQYVSSEKDGKATGWTAFYIDGEWQVTKK
(649) DNA topoisomerase 3 [Sodalis glossinidius str. 'morsitans']
10
MQLFIAEKPSLARAIADVLPKPHRRGDGYIACGPDHVVTWCIGHLLEQAQPDVYDGRYARWSLADLPIIPEKWRLQPRPSVQKQLDVIKTLLAKAERVIHAGDPDREGQLLVDEVLDYLALDEAKRRDAKRCLVNDLNPQAVSKAVSRLRENSEFVPLCVSALARARADWLYGINMTRAYTLIGLNAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFIPKAYFEVKAHIVTPSQERFIALWVPSDACESWQDEEGRLLHRPLAEHVVARITSQPAYVMLYQDKRESEAAPLPFSLSALQIEAAKRFGLSAQQVLDTCQRLYETHKLITYPRSDCRYLSEEHFAGRQAVLAAIAAHQPALMTQGQLNTDQRNRCWNDKKVDAHHAIIPTARTSRATLNDSEQKIYALVARQYLMQFCADAVFRRCIIELDIAGGKFFVRARFLAEAGWRALLGAKERDEEDEGTPLPVVAKGDALLCECGEVVARETQPPRPFTDASLLSAMTGIARFVQDKALKKILRATDGLGTEATRAGIIELLFKRGFLFKQGRYIHASETGRGLIHALPPSAASPDMTAQWEASLTQISEKQCRYQDFMQPLTHTLQQLIEQARQQPAPSSLRGLPPASEKPALKQARRKRKPP
(1531) DNA topoisomerase 1 [Pectobacterium carotovorum subsp. carotovorum PC1]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSVSKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWQANYEILPGKEKVVSELKTLAENADHIYLATDLDREGEAIAWHLREIIGGEDERFSRVVFNEITKNAIKQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHSGKPFKPVNKEQTQAAVSLLENARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPESANLYSSKENSQEAHEAIRPSDVGVLADSLKDMETDAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEALSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALSPKERCKTTINLIPENEVLNVLEGDDAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIETGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTSETCSNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLAEAPVVDKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(1549) DNA topoisomerase 3 [Pectobacterium carotovorum subsp. carotovorum PC1]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGQNDVVTWCVGHLLEQAQPDVYDARYARWSLADLPIIPQKWLLQPRPSVSKQLNTIKKLLNDANEVIHAGDPDREGQLLVDEVLEYLALPEEKRQQVRRCLINDLNPQAVERAVSRLRENREFIPLCVSALARSRADWLYGINMTRAYTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVAKDYFEVKAHIVTPADERFVALWQPSESCEPYQDEEGRLLHRSLAEHVVKRIEGQPAFVTSYNDKRESETAPLPYSLSTLQIEAAKRFGLSAQQVLDVCQKLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAISVHQPDLLPQPVMDVDRRNRCWDDGKVDAHHAIIPTARSASASLTENERKVYGLVARQYIMQFCPDAVFRKCVIELDIAGGKFITKARFLAEAGWRTLLGGKERDEENEGMPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRTFLFKKARYIHASEAGRALIHSLPASAAHPDMTAHWEATLTQISEKKCRYQDFMQPLTHSLQELIQQAKQNGAVRAFKGLSAPQSGAAKRRKPQTKKAKEQEQ
(1645) DNA topoisomerase 3 [Yersinia pseudotuberculosis IP 32953]
10
MMRLFIAEKPSLARAIADILPKPHRRGGGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALWQPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEGKVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPSGAPKKRKKISSKAKESKS
(1341) DNA topoisomerase 1 [Yersinia pseudotuberculosis IP 32953]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSANSAEEKAKKDDKPKKKVKKDEKVALVNRMGVDPYHGWKAQYEILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNISRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLVAKGDIPIQMEVTHAHGKPFKPVNREQTHAALTLLENARYKVLDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPATPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQRLYQLIWRQFVACQMPPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSDLDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKTVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPDAEILNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVVDKEGNKTLVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEAKK
(1569) DNA topoisomerase [Xenorhabdus bovienii SS-2004]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDDCDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVTFTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTALPALKKEEICPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLLARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVTGSRKTRRGNSPD
(143) DNA topoisomerase 3 [Xenorhabdus bovienii SS-2004]
10
MRLFIAEKPSLARAIADILPKPHRRGDGFIECGNNQFVTWCVGHLLEQAEPDTYDSRYARWVLSDLPIIPEKWRLKPRAAVAKQLNTIKSLLEKADEVIHAGDPDREGQLLVDEVLDFLNLRDDKKQNVQRCLINDLNPQAVIKAVERLRSNREFIPLCVSALARARADWLYGINMTRAYTLLGQNAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFVPKDFFEVKAYIVTPNEEQFTALWQPSESCIDFQDEEGRLIHQPLAEHVVARITGQPAYVTAYQDKRESETAPLPFSLSSLQIEAAKRFGLSAQNVLDICQRLYETHKLITYPRSDCRYLPEEHFVGRHAVLNAISIHSSDLLPQDALESDKKNRCWDDKKVDAHHAIVPTARSSQVNLTENERQIYGLIARQYLMQFLPDAVFRKCTIELDIAGGKFIAKARFLAEAGWRTLLGNKERDEENEGTPLPVVAKGDELLCEKGEVVERQTQPPRPFSDATLLSAMTGIARFVQDKSLKKVLRATDGLGTEATRAGIIELLFKREFLYKKGRNIHATPAGRALIHVLPDMAVLPDMTAHWESKLTQISEKQFRYQDFMLPLQETLQQLIWQAKQYRNLKAFRDLPPVPMKGKKGKTKQVKKGKEKVNKTE
(1819) DNA topoisomerase 1 [Xenorhabdus bovienii SS-2004]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGAASQKSSNSSTDKNKKKKDEKTALVNRMGVDPYHGWEADYQILPGKEKVVAELKMLAEKADHIYLATDLDREGEAIAWHLREVIGGGEARFSRVVFNEITKNAITQAFDNPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWQLHADLMAKGDIDLHMEVTHEGGKPFKPINAQQTQAAVSLLEKARYKVLDREDRPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALDMVRGYINDQFGDKYLPKTANIYSNKENSQEAHEAIRPSSVDVMAEELKDMEADAQKLYQLIWRQFIACQMMPAKYDSTTLTIQAGNFELRAKGRTLRFDGWTKVMPALRKGDEDHTLPVVEVGTELDLKQLSPSQHFTKPSARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRGENRRFYAEKMGEIVNDRLEENFNELMSYDFTARMEDQLDHVANNEANWKGVLDEFFTNFSEQLDVASKDPDEGGMRPNPMVSTSIDCPTCSRPMGIRTATTGVFLGCSGYTLSPKERCKQTINLIPENEILNILEGDEAETNALRARHRCKECGTAMDSYLIDNQRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGSEMHLKMGRFGKYMGCTSEECKNTRKILRSGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAASTFPKSRETRAPLVEELVKFKDRLPEKLCYLAKAPVADPEGHKTVVRFSRKTKQQYVSSEKNGKATGWAAFFVDGAWVVKEK
(1568) DNA topoisomerase [Xenorhabdus bovienii SS-2004]
4
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDDCDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVTFTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTALPALKKEEICPVLRAEIQPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLLARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANAVTGSRKTRRGNSPD
(1336) DNA topoisomerase 3 [Edwardsiella tarda EIB202]
10
MRLFIAEKPSLGRAIADVLPKPHRRADGYIQCGDGDVVTWCVGHLLEQAEPDAYDARYARWNLADLPIVPQKWQLRPKASSAKQLKVIEHLLRDAQQVVHAGDPDREGQLLVDEVLDFLALAPEKRRQVQRCLINDLNPQAVARALERLRDNHEFMPLCVSALARARADWLYGINMTRAYTLLGRNAGYNGVLSVGRVQTPVLGLVVRRDEEIAHFVAKDYYEVRAHIVTPAGERFWAQWQPSEACEPHQDEEGRLLNRALAEHVIARIQDKPARVTGYNDKRESEVAPLPFSLSALQIEAAKRFAMSAQQVLDTCQRLYETHKLLTYPRSDSRYLPEEHFAGRHAVMAAIAAHAPTLANLESVDVQRRNRCWDDSKVDAHHAIIPTARAGSVALNEDERNIYQLVARQYLMQFCPDAQYRKCVIDLEIEGGIFIAKARFLSQAGWRALLGAKERDDEDEGMPLPVVARDDLLHCERGELMARQTQPPRHFTDASLLSAMTGIARFVQDKSLKKILRATDGLGTEATRAGIIELLFRRGFLHKKGRYIHASPAGSALIHCLPEMAGRPDMTAHWEATLTKISERGCRYQDFMHPLVETLQQLIHQARTAVNPRAFRDLPPAESARPRRAKGASTASNKRKKA
(1290) DNA topoisomerase 1 [Edwardsiella tarda EIB202]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKGAASADDKAKTKAKKNERDALVNRMGVDPYHGWQAHYEVLPGKEKVVSELKSLAEKADHIYLATDLDREGEAIAWHLREVIGGDDSRYSRVVFNEITKNAIQQAFSQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLIVEREREIKAFVPEEYWELRADLAVGAEVSFQAQVTHCNDKPFKPVNAAQSQAAVAALEHARFAVREREDKPTSSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALNMVRAYIGDNFGAEYLPADANVYASKDNSQEAHEAIRPSDVNVLADDLKGMEADALKLYQLIWRQFVACQMTAAKYDASTITVQAADYTLKARGRTLRFDGWTRVLPQLRKGDEDRALPAVESGRALDLLQLQPSQHFTKPPARFSEASLVRELEKRGIGRPSTYAAIISTIQDRGYVRTDNRRFYAEKMGEIVTDRLEENFRELMSYDFTAHMEDGLDRVASAQADWKVMLDGFFSDFSQQLEVAEKPPEEGGMRPNPMVLTSIACPTCERQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPEAEVLNVLEGDDAETNALRAKRRCPKCGTAMDSYLIDNHRKLHVCGNNPACDGYEVEEGEFRIKGYDGPIVECDKCGAEMHLKMGRFGKYMGCTNEACKNTRKILRNGEVAPPKEDPVPLPELACEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLAEAPQQDEQGNATLVRFSRKTKQQYVSSEKEGKATGWTAFFIDGKWVVSEKK
(772) DNA topoisomerase 3 [Klebsiella oxytoca KCTC 1686]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDARYARWNLLDLPIVPEKWQLQPKPSVTKQLNVIKRLLGDAQEVIHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPKDERFVATWVPSEACEPYQDEEGRLLHRSLAEHVVKRIEGQPATVTAYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIGVHAADLLPQPVVDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLSDNEEKVYGLIARQYLMQFCPDAVFRKCQIDLDIANGKFVAKARFLAEAGWRTLLGNKERDEENDGMPLPVVAKDDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESILTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRRFRGIVAPGDGKKSFSKGKGRAKAKDKKSAAGPAAESPQ
(60) DNA topoisomerase 1 [Klebsiella oxytoca KCTC 1686]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTSTKGAKKPKKDERGALVNRMGVDPWHDWNAHYEILPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDEQRYSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWEVDASTTTPGGDALPLQVTHNGDKPFRPVNRDETMAAVALLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYIGDNFGKKYLPESANQYASKENSQEAHEAIRPSDVNVLAETLKDMESDAQKLYQLIWRQFVACQMTPAQYDSTTLTVKAGDFKLKARGRTLRFDGWTKVMPALRKGDEDRTLPMVNKGDSLSLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRDLMNYDFTAQMEDRLDQVANHQAEWKQVLDSFFGDFTSQLQTAEKDPEEGGMQPNPMVLTTIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCKKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLAEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVASEKDGKATGWSAFYIDGKWTEAKK
(1188) DNA topoisomerase 3 [Erwinia billingiae Eb661]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGQDQMVTWCVGHLLEQAQPDSYNSRFARWSLADLPIVPEKWQLKPRPSVAKQLNVIKGLLEQATEVVHAGDPDREGQLLVDEVLDYLSLPPEKRANVQRCLINDLNPSAVERAVSRLRENKEFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYDGLLSVGRVQTPVLGLVVRRDEEIENFIAKDFFEVKAHIVTPKDERFVALWQPSDSCEPYQDEEGRLLHRPLADHVLARIGGQPANVTSYNDKRENDTAPLPFSLSSLQIEAGKRFGMSAQTVLDTCQKLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINAHQPDLTPPADFDSDRRNRCWDDKKVDAHHAIVPTARSSQVRLTENESTIYRLIATQYLMQFCPDAVYRKCVIELDIAGGKFVAKARFLAEAGWRSLLGSKERDEENDGTPLPVVAKGDELLCERGEVVEKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRAFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFMLPLVETLHNLIYQARQQPAAHAFRGLPAAEPKKPRRKATKAKETE
(686) DNA topoisomerase 1 [Erwinia billingiae Eb661]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKPAKKVKKDEKAALVSRMGVDPFHGWEADYQILPGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDSRFSRVVFNEITKNAIRQAFEKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFTPEEYWELHADLNTPKGTGLPMEVTHQHDKPFRPVNGEQTHAAVSLLEKARYVVADREDKPTSSKPGAPFITSTLQQAASTRLGYGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDAVSMVRGYIETEFGAKYLPKAANVYSSKENSQEAHEAIRPSDVAIQSEQLKDMEADAQKLYQLIWRQFVACQMMPAQYDSTTLTVAAGDFKLKAKGRTLRFDGWTAVMPALRKGDEDRTLPPVEVGEELKLQQLKPSQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEANFRELMNYDFTAHMEDNLDKVANNEAQWKGVLDQFFADFSQQLEKADKDPEEGGMQPNQMILTSIDCPTCNRKMGIRTASTGVFLGCSGYALPPKERCKQTINLIPENEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPGCDGYEIEQGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGDVAPPKEDPVPLPELTCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELQRFRDRLPEKLSYLADAPVSDEEGNKAVVRFSRKTKQQYVSTEKDGKATGWSAFYVDGKWEVASKATATKAAPVKAAANKATATKATAKKAAKK
(935) DNA topoisomerase 3 [Serratia sp. AS12]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGNNDVVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPSVSKQLNAIKKLLHDADEVVHAGDPDREGQLLVDEVLDYLALTPEKRHSVRRCLINDLNPQAVERAIDRLRDNRDFIPLCVSALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPKEERFVALWQPSDSCEPYQDEEGRLLHRPLAEHVLKRIEGQPALVTSYNDKRESDTAPLPFSLSTLQIEASKRFNLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAISAHQPDLYPQPVIDSDRRNRCWDDKKVDAHHAIIPTARASKVSLSQDELNVYGLVARQYLMQFCPDAMFRKCVIELDIAGGKFVAKARFLAEAGWRTLLGSKERDEENEGSPLPVVAKDDELLCERGEVVERQTQPPRPFTDASLLSAMTGIARFVQDKALKKILRATDGLGTEATRAGIIELLFKRAFLYKKGRYIHSSETGRALIHSLPDIAARPDMTANWEATLTQISEKSCRYQDFMQPLVGTLQELIYQAKQSRASMAFRGLPPSPSAGAKKRKKSAGKAREKSE
(1639) DNA topoisomerase 1 [Serratia sp. AS12]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSADSTEDKAKKKVKKDEKTALVNRMGVDPYHGWKADYEILPGKEKVVAELKSLAENADHIYLATDLDREGEAIAWHLREVIGGDEKRFSRVVFNEITKNAIQQAFKQPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVERERDIKAFVPEEYWELHADLLAKNDTALQMEVTHAHDKPFKPVNREQTHAALKLLEKARYTVLDREDKPTSSKPGAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALNMVRGYIGDNFGDKYLPKAPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLSVKAGDYQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPYVEVGSDLELQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVESRRFYAEKMGEIVTDRLEENFRELMNYDFTARMEDGLDQVANNHAEWKAVLDEFFAEFSEQLETAEKDPEDGGMRPNQMVMTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPETEVLNILEGDDAETNALRARHRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEEGEFRLKGYDGPVVECDKCGSEMHLKMGRFGKYMGCTNETCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELARFKDRLPEKLRYLADAPVADGEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(40) DNA topoisomerase [Serratia sp. AS12]
4
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANYCDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFWGCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE
(15) DNA topoisomerase 3 [Dickeya zeae Ech1591]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGDQDTVTWCVGHLLEQAQPDAYDARYARWSLTDLPIVPQKWLLQPRPSVSKQLNVIKKLLTQADEIIHAGDPDREGQLLVDEVLEYLALSEEKRQHVRRCLINDLNPQAVERAVSRLRENREFVPLCVSALARSRADWLYGINMTRAYTLLGKNAGYEGVLSVGRVQTPVLGLVVRRDEEIDNFVPRDYFEVKAHIVTPANERFVALWQPSESCEPYQDDEGRLLHRPLAEHVVKRIEGQPAWVTAYNDKRESETAPLPYSLSALQIEAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRQAVLNAIATHRPDLLPQPAVDPERRNRCWDDGKVDAHHAIIPTARSARTSLTEQESQVYGLVARQYLMQFCADAVFRKCVIDLDIAGGKFVAKARFLAEAGWRTLLGNKERDEENEGMPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKALKKILRETDGLGTEATRAGIIELLFKRAFLIKKGRYIHSTDAGKALIHALPPIAAHPDMTAHWEATLTQISEKRCRYQDFMQPLTQSLYELIQQARQSGNIQAFRGLPAVKRATPEKRKRRQSRSASTKE
(1778) DNA topoisomerase 1 [Dickeya zeae Ech1591]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSGSASKKSAEANGEKAKKAVKKDERTALVNRMGVDPYRGWQAHYEILPGKEKVVSELKMLAQNADHVYLATDLDREGEAIAWHLREIIGGDEKRFSRVVFNEITKNAIRQAFENPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEYWELHADLLANAETALQMQVTHHHGKPFRPVNQAQTQAAVSLLEKASYVVNEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMARDYIQGEFGKRYLPDAPNLYTSKENSQEAHEAIRPSDVSVLADQLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLVVSAADYQLRAKGRTLRFDGWTKVMPALRKSDEDRTLPAVEIGQSLSLEKLSPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEDNFRELMNYDFTARMENSLDLVANSQAEWKAVLDEFFAEFSQQLETAEQEPDEGGMKPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLIPEAEVLNVLEGDEAETNALRARRRCSKCGTAMDSYLIDNQRKLHVCGNNPSCDGYEIEQGEFRLKGYDGPVVECEKCGSEMHLKMGRFGKYMACTSDSCGNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFRDRLPEKLRYLADAPVTDPQGNKTLVRFSRKTKQQYVSSEKEGKATGWSAFYVDNKWVETAR
(1586) DNA topoisomerase [Dickeya zeae Ech1591]
4
MRLFLCEKPSQGKDIGRVLGTTQRGNGCLTGSGITVTWCIGHLVEAAPPETYGEQYKRWSIEQLPIIPECWRVEVKSKTASQFNVVKELLSKATELVIATDADREGELIAREIIELCGYRGPIQRLWLSALNDTSIRKALSVLRPSDETLPMYFSALARSRADWLIGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWAVEVVLSSAGQHFTAAWLAPDTAADNAGRCLQEPIARQATERMRVTGSAQVTSVETEHMREGPPLPFDLGTLQEVCSRQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPIVFDSLLKTDPDLRPIVDLLDRNQRSRAWNDSKVTAHHGIIPTLEPANLAAMSDKERAVYTLIRTHYLAQFLPHHEFDHTTAYLSCAGEMLQAVGKQVVLVGWRRVLTEPKPDDDGDTTSRSQVLPPLNEGLSCQITGIDCKALKTSPPRPYTQGELVKSMKSVAKLVSDPRLKQTLKDTTGIGTEATRANIIKGLLDRGYLLKKGRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIESGQLTLDVFIDKQSAWIAQLIQQYRGASLSIQMPLGPACPECGTPMHQRPGKNGAFWSCPRYPDCRGSLPIDSGKRKRTTPRKRNSSLQAS
(1641) DNA topoisomerase 3 [Shigella dysenteriae Sd197]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRYLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSGFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKARIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGRKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEAGSGAIV
(1216) DNA topoisomerase 1 [Shigella dysenteriae Sd197]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSYFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPENLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(897) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKASYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1734) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(358) DNA topoisomerase 3 [Erwinia pyrifoliae Ep1/96]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNSRFARWSLDDLPIVPEKWRLQPRPSVAKQLNVIKGLLAQASVVVHAGDPDREGQLLVDEVLDYLTLPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAYTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVRAHIVTPADERFVALWQPSASCEPYQDEEGRLLHRPLAEHVVARIGGHPAHVTSYNDKRENETAPLPFSLSALQIEAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINVHQPNLSPPGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQVSLSDNEQQIYRLIATQYLMQFCPDAVYRKCVIELDIAGGKFVAKARFLAEAGWRALLGSKERDEENDGTPLPVVTKGDELLCERGEVQEKQTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFMSPLVDTLHSLIQQARQQPAAHAFRGLPAPATDKTKRPRRKTAQKKESET
(1770) DNA topoisomerase 1 [Erwinia pyrifoliae Ep1/96]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSTVKKSADSTTSKTTKKVKKDEKTALVNRMGVDPFHGWEANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGDESRYSRVVFNEITKNAIRQAFDRPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLVVDREREIKAFVPEEYWELNADLTTPKGVDLPMQVTHQHDKPFRPINREQTYAAVSLLEKARYVVVDREDKPTGSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALSMVRGYVEEEFGAKYLPKTANLYSSKENSQEAHEAIRPSDVKVQSEQLKDMDADAQKLYQLIWRQFVACQMVPAQFDSTTLTVEAADFKLKAKGRTLRFDGWTRVMPALRKGDDDRTLPAVEVGSELSLQQLLPGQHFTKPPARFSEASLVRELEKRGIGRPSTYASIISTIQDRGYVKVESRRFYAEKMGEIVTDRLEENFRELMNYDFTAHMEDNLDKVANNEAQWKAVLDQFFGDFSQQLEQAEKDPEEGGMQPNQMVLTSIECPTCSRQMGIRTASTGVFLGCSGYALSPKERCKQTINLIPENEVLNILEGDDAETNALRARRRCGKCGTAMDSYLIDNQRKLHVCGNNPECDGYDIEQGEFRIKGYDGPVVECEKCGSEMHLKMGRFGKYMACTNDDCKNTRKILRNGDVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPQVEELQRFRDRLPEKLRYLADAPAKDADGNKAVVRFSRKTKQQYVSTEKDGKASGWSAFYVDGKWEVTKK
(787) DNA topoisomerase 3 [Pectobacterium wasabiae WPP163]
10
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGQNDVVTWCVGHLLEQAQPDVYDARYARWSLADLPIIPQKWLLQPRPSVSKQLSAIKKLLNDASEVIHAGDPDREGQLLVDEVLEYLSLSEEKRQQVRRCLINDLNPQAVERAVSRLRENREFIPLCVSALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVSKDYFEVKAHIVTPADERFVAIWQPSESCEPYQDEEGRLLHRSLADHVVKRIEGQPAFVTSYNDKRESEIAPLPYSLSTLQIEAAKRFGLSAQQVLDVCQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAISVHQPDLLPQPVMDVDRRNRCWDDGKVDAHHAIIPTARSASASLTENERKVYGLVARQYIMQFCPDAVFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGGKERDEENEGMPLPVVAKGDELLCERGEVVERQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRTFLFKKARYIHASEAGRALIHSLPDSAAHPDMTAHWEATLTQISEKKCRYQDFMQPLTNSLQELIQQAKQNGAVRAFKGLSAPPSGASKRRKPQAKKAKEQKQ
(1350) DNA topoisomerase 1 [Pectobacterium wasabiae WPP163]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHVRDLPTSGSASKKSADSTTKDKTKKKVKKDEKSALVNRMGVDPYHGWKANYEILPGKEKVVSELKTLAENADHIYLATDLDREGEAIAWHLREIIGGDDRRFSRVVFNEITKNAITQAFEKPDTLNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLIVDREREIKAFVPEEYWELHADLLAGSDIQLQMQVTHHNGKPFKPVNKAQTHAAVSLLENARYIVADREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDALTMVRGYIGEEFGKRYLPEAAIAYSSKENSQEAHEAIRPSDVGVLADSLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLIVEAADYQLRAKGRTLRFDGWTKVMPALRKNDEDRTLPTVAVGEALSLQKLLPGQHFTKPPARYSDASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESRLDQVANNQAEWKAVLDEFFNEFSQQLEKAEQDPEEGGMRPNAMVLTSIDCPTCSRQMGIRTASTGVFLGCSGYALSPKERCKTTINLIPETEVLNVLEGDEAETNALRARRRCEKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIETGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMSCTGETCSNTRKILRNGDVAPPKEDPVPLPELSCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPEVDKDGNKTQVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEGKK
(556) DNA topoisomerase [Pectobacterium wasabiae WPP163]
4
MCEKPSQGKDIGRVLGATQRGNGCLAGSGITVTWCIGHLVEAAPPETYGEQYKRWSIEQLPIIPERWRVEVKSKTASQFNVVKNLLSKATELVIATDADREGELIAREIIELCGYHGPIQRLWLSALNDASIRKALAALRPSGETLPMYFSALARSRADWLIGMNLSRLFTVMGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTVETVLSSAGQSFTAGWLAPDTATDDAGRCLQEPIARQAAERMRIAGSAQVTSVETERLREGPPLPFDLGTLQEICSKQLGLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPVVLDSLLKTDPGLRPIVDQLDRNQRSRAWNDSKVTAHHGIIPTLEPANLTAMSDKEQAVYKLIRAHYLAQFLPQHEFDRTTACLSCTGETLQAVGKQIVVIGWRQVLTEPRPDEDGETTLRSQVLPALHEGLSCQITGIDCKALKTSPPRPYTQGELVKAMKGVAKLVSDPRLKQKLKDTTGIGTEATRANIIKGLLDRGYLLKKSRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWITQLVQQYRGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDSGKHKRAMPRKRSRSSREP
(551) DNA topoisomerase [Pectobacterium wasabiae WPP163]
4
MRLFICEKPSQARDIAAVLGATKRGQGFLSAPGITITWARGHLLETASPEVYGTQFEKPWRIDVLPVLPPVWQMVVKSESSDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYCGWRGPVFRLWLSALDESSIRAALAAIKPGSETKPLYYAGLGRSRADWLIGMNLTRLYTVKARDKGYDGLLSVGRVQTPVLAMVVNREREIATFVPKPYWQVWVALQSNGVRFSAQWVPAKMYVDEEKRCIHQDIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRLWDMSPQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQALISQLDTRFVSRIWDDKKMTAHHGIIPTRHVCDMSKMSDQEKQVYVLIRRHYLAQFFPLHEVDFTRLSLNIGGQLFQTTGRVVVVPGWKRLFSQDDGEHKEAAADEKDQSLPMLVKGDNCGVAGSEVKALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLLARNFISIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGRMTLDSFMSRQTQWICQLVSLGTQQDVVVRVPPTPACPLCGSKTRLRKGAKGAFYGCEKYPDCKGMINVPGQSKNAASKTRKKKQN
(120) DNA topoisomerase 3 [Proteus mirabilis HI4320]
10
MRLFIAEKPSLARAIADVLPKPHKRGDGFIVCGDNQYVTWCVGHLLEQAEPDAYDPRYARWSLDDLPIIPNKWQLKPRADVKKQLDTINTLLKQADEVIHAGDPDREGQLLVDEVLNYLNISDAQRKQARRCLINDLNPAAVSRAIDKLRYNHEFIPLCVSALARARADWLYGINMTRAYTLLGQRNGYQGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPADERFTAIWQPSEHCEPWQDEEGRLLHRKLAEHVVDRIAGKPANVTDYQDKQESEIAPLPFSLSALQIEAAKRFGLSAQQVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVMNAISVHDNSLLPQETLDIDKKNRCWDDKKVDAHHAIIPTAKTGNISLSENEKNIYYLIARQYLMQFMPDAVYRKCVIELDIENGKFIAKARFLAQAGWRTLLGSKEQDAENDGSALPIVAKGDELLCEKGEIVAKQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRGFLQKKGRAINSTPAGRALIHVLPDMATLPDMTAHWESILTQISEKQFKYQDFMMPLSNTLFELITQAKRRPNIQAFRNLPAPAQNKKRKGATKKSAQGKSRSAQSQSTNRNIKSDA
(1301) DNA topoisomerase [Proteus mirabilis HI4320]
4
MKLFLCEKPSQAKDIARVIGAHQRRDNFFQGNGVQVAWARGHLLEQAEPEAYGAQFAAPWRQSALPVIPEQWKMVVKKDAVSLFQTIKQLLSQATEVVIATDADREGEVIARELLEACHYRKKVQRLWLSALDEASIRQALNNLLPGEKTASLYSAGLGRARADWLIGMNMTRLFTLKARELGFGGILSVGRVQTPTLALIVRREREITHFVSKPFWRVTASLQHQGIIFQAHWRPASQYCDDEHRCIHVQAAQAVEQLCRQAGKATVCTVNETKGKALPPLPFDLGTLQQAASRRWGYSADKVLEIAQSLYEKHKATTYPRTDCGYLPVSMRADIPVVLDALSQSDPALQNVLAQLQPARISRVWNDAKITAHHAIIPTRQTPDLNAMNEAELNVYKLIRAHYLAQFLPDQEWDATEVFLDIGGQQFVAKGKVERVKGWSVLFVKHEDDPPVKEEAETGLEAGTETLPSLHEGEFCVVQEAKVVQLATSPPKPYTDGTLIAAMKNASSFITDPTLKKVLKENAGLGTEATRAGIITTLENRKLIVRQKKTLRATDTGCQLIDALPAACTDPGMTALWEQSLEQVAQGNLSLDVFMQKQISWLAHLIKKGGEMPLALDLPPMPSCPSCHGKMVLRESSKGRFWSCQRYPDCKGSVPLPEKMQGVTRGMNKRKKAVKKSITGLFT
(1656) DNA topoisomerase 1 [Proteus mirabilis HI4320]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPKSGSGSQKSENSSATKGVKKVKKDEKSALVSRMGVDPYNGWHANYQILPGKEKVVAELKALAEKADHIYLATDLDREGEAIAWHLREVIGGEDDRFSRVVFNEITKNAITQAFQTPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKVARGLSAGRVQSVAVRLLVEREREIKAFVPEEYWQLHASLLTPDEQPLRMEVTHYQDNAFKPVSSEETQVAVKALQNATFIVKNREDRPTSSKPSAPLITSTLQQAASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDAIQMARDYIHDKFGAKYLPKEPNVYSSKENSQEAHEAIRPSDINVTAESLKDMDSDAKRLYQLIWDQFVACQMTPAKYDSTTLTVVSGDYKLRAKGRTLRFAGWTKVMPAMRSKDEDKTLPAVDVGAQLALAELSPTQHFTKPPARFSEATLVKELEKRGIGRPSTYASIISTIQDRGYVKVENRRFYAEKMGEIVTDRLEENFSDLMNYDFTAQMEDHLDHVANNQENWKAVLDAFFTDFSQQLEVAEKDPEEGGMRPNPMVITSIECPTCSRHMGIRTATTGVFLGCSGYALPPKERCKQTINLIPEDELLNILEGDDAETNALRARRRCPKCGTAMDSYLIDTHRKLHVCGNNPACDGYEVEEGEFRLKGYEGPVIECDKCGAEMHLKMGRFGKYMGCTNEECKNTRKILKSGEIAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPKVAELVRFKDRLSEKMRYLAQAPVTDPEGNPTIVRFSRKTKQQYVSSEKEGKATGWSAFYIDGKWVEKSK
(514) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Heidelberg str. SL476]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPPAEETGRQTE
(1555) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Heidelberg str. SL476]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(725) DNA topoisomerase 3 [Salmonella enterica subsp. enterica serovar Agona str. SL483]
10
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVDTLYQLIEQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPPAEETGRQTE
(1136) DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Agona str. SL483]
9
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNINRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPTSSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQLIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTLPAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALSPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFVDGKWVEGKK
(1869) DNA topoisomerase 1 [Shigella sonnei Ss046]
9
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTIGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKIGEIVTDRLEENFRELMNYDFTAQMENSLDLVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
(131) DNA topoisomerase 3 [Shigella sonnei Ss046]
10
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIIPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERALDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLLQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDVVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEVGSGAIA
Family distribution
Taxonomy tree
Enterobacteriales